Hub : Genes

Cpeb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg mRNA stability Cpeb3 0.18 0.17 6.2e-03 0.03 0.06 0.04 0.05 7.2e-02 1.0e-02 3.3e-02 1.6e-02
2 PL mRNA stability Cpeb3 0.05 0.03 5.7e-06 0.05 0.05 0.05 0.05 2.1e-06 3.2e-06 5.6e-06 2.7e-06
3 Liver intron excision ratio chr1_234774205_234783376 0.05 0.04 2.0e-04 0.03 0.03 0.03 0.03 9.3e-05 5.3e-04 1.3e-04 6.5e-04
4 Liver intron excision ratio chr1_234783490_234795956 0.06 0.05 7.6e-05 0.04 0.03 0.02 0.03 4.0e-05 3.6e-04 1.4e-03 2.8e-04
5 NAcc mRNA stability Cpeb3 0.06 0.04 5.7e-06 0.05 0.05 0.04 0.05 2.3e-06 2.2e-06 5.3e-06 4.9e-06
6 pVTA mRNA stability Cpeb3 0.17 0.1 9.0e-07 0.16 0.15 0.15 0.16 1.7e-07 3.3e-07 5.5e-07 1.4e-07
7 Adipose mRNA stability Cpeb3 0.07 0.05 2.0e-07 0.04 0.04 0.04 0.04 9.3e-06 1.1e-05 6.9e-05 6.9e-05
8 NAcc alternative TSS NM_001419824.1 0.02 0.02 5.7e-03 0.02 0.01 0.02 0.02 1.1e-03 6.3e-03 4.2e-03 2.7e-03
9 NAcc alternative TSS NM_001419824.1 0.02 0.02 3.8e-03 0.01 0.02 0.02 0.02 1.0e-02 4.0e-03 1.2e-03 3.3e-03
10 BLA gene expression Cpeb3 0.09 0.06 4.3e-03 0.03 0.03 0.03 0.02 1.1e-02 6.3e-03 9.3e-03 2.2e-02
11 Brain mRNA stability Cpeb3 0.16 0.09 4.3e-11 0.11 0.11 0.12 0.12 3.7e-10 1.1e-10 3.5e-11 4.4e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density6.911.518.7-4.23.4-3.73.7-3.2-3.94.03.14.30.00.1
Area under the delay curve0.50.50.91.0-0.80.7-0.70.60.7-0.6-0.8-0.90.4-0.5
BMI with tail0.10.30.6-0.70.4-0.40.4-0.3-0.80.80.70.8-0.10.3
BMI without tail0.10.10.3-0.50.1-0.10.1-0.1-0.30.30.30.5-0.40.5
Body weight1.04.36.7-1.72.4-2.52.5-2.6-2.11.92.51.11.4-1.2
Weight adjusted by age0.20.30.7-0.1-0.70.7-0.70.9-0.00.2-0.6-0.1-0.30.3
Bone surface3.86.711.7-3.32.6-2.82.8-2.5-2.72.72.43.4-0.70.8
Bone volume4.98.312.2-3.43.0-3.33.3-2.9-3.13.22.83.50.2-0.0
Breakpoint value in progressive ratio session0.91.02.2-0.51.0-0.90.9-1.0-1.11.10.80.11.4-1.5
Number of licking bursts2.12.54.22.0-2.01.9-1.91.91.6-1.6-1.6-0.90.0-0.1
Context. condit. distance diff. score2.22.63.5-1.11.7-1.81.8-1.9-1.71.61.70.11.8-1.7
Locomotion velocity, session 13.33.65.61.0-2.32.0-2.02.41.7-1.8-1.80.4-2.42.2
Locomotion distance, session 10.20.30.70.3-0.80.5-0.50.70.4-0.3-0.50.2-0.60.6
Locomotion velocity, session 20.80.91.60.8-1.30.9-0.91.11.0-1.0-0.80.0-1.11.0
Locomotion distance, session 20.20.30.80.9-0.70.4-0.40.40.6-0.7-0.6-0.60.3-0.3
Locomotion velocity, session 30.20.20.4-0.20.6-0.60.6-0.6-0.30.10.5-0.30.4-0.5
Locomotion distance, session 31.01.12.3-0.11.1-1.11.1-1.3-0.60.40.9-0.71.5-1.5
Stereotopy head waving bouts, day 30.40.51.8-0.4-0.30.3-0.30.50.2-0.1-0.20.9-1.31.3
Stereotopy head waving duration, day 30.30.31.1-0.4-0.40.4-0.40.60.00.1-0.20.5-1.01.0
Locomotion velocity, session 70.91.03.70.00.6-0.70.7-0.8-1.00.90.7-0.41.9-1.9
Locomotion distance, session 70.91.13.0-0.30.8-0.80.8-1.0-1.11.10.7-0.31.7-1.7
Stereotopy head waving bouts, day 70.20.20.8-0.1-0.10.1-0.10.10.5-0.5-0.30.2-0.80.9
Stereotopy head waving duration, day 70.40.52.1-0.60.4-0.30.3-0.20.3-0.40.10.7-1.41.4
Locomotion velocity, session 80.30.30.5-0.60.7-0.70.7-0.6-0.70.70.50.20.3-0.3
Locomotion distance, session 80.60.82.80.00.5-0.70.7-0.8-0.80.70.5-0.51.7-1.7
Degree of sensitization distance0.30.30.40.5-0.60.7-0.70.6-0.00.3-0.6-0.50.6-0.6
Degree of sensitization stereotypy0.20.20.6-0.50.6-0.50.5-0.50.1-0.20.10.4-0.70.8
Conditioned locomotion0.50.60.9-0.60.8-0.90.9-0.8-1.00.90.80.30.9-0.8
Cocaine response after cond. corrected0.00.00.1-0.20.3-0.20.2-0.0-0.00.2-0.10.1-0.30.3
Cocaine response after cond. not corrected0.20.20.3-0.00.6-0.50.5-0.5-0.10.20.1-0.40.6-0.5
Cocaine response before conditioning0.30.41.20.8-0.1-0.10.1-0.20.4-0.6-0.1-1.11.0-1.0
Saline control response0.40.51.50.8-0.40.4-0.40.40.10.0-0.2-1.01.1-1.2
Bone: connectivity density4.16.413.9-3.52.4-2.52.5-2.0-2.93.12.03.7-0.60.8
Bone: cortical apparent density1.82.33.41.3-1.51.8-1.81.81.6-1.4-1.8-1.4-1.01.0
Bone: cortical area3.04.57.9-1.72.6-2.72.7-2.8-1.91.72.41.11.4-1.2
Bone: cortical porosity0.10.10.20.5-0.50.4-0.40.40.3-0.3-0.3-0.40.2-0.2
Bone: cortical porosity0.00.00.00.0-0.0-0.10.1-0.1-0.10.00.2-0.00.2-0.2
Bone: cortical thickness0.30.51.00.10.7-0.80.8-1.0-0.20.10.6-0.31.0-1.0
Bone: cortical thickness0.50.61.61.1-0.80.7-0.70.60.7-0.7-0.8-1.30.5-0.5
Bone: cortical tissue density1.82.43.51.3-1.61.9-1.91.91.6-1.4-1.9-1.4-1.01.0
Condit. Reinf. active minus inactive responses0.80.81.91.4-1.10.9-0.90.81.1-1.2-0.6-0.90.2-0.4
Condit. Reinf. active-inactive response ratio0.91.01.70.9-1.11.1-1.11.01.2-1.3-0.9-0.3-0.90.9
Condit. Reinf. active responses0.30.41.60.7-0.1-0.10.1-0.30.1-0.30.3-0.71.1-1.3
Condit. Reinf. inactive responses0.91.12.4-0.30.8-1.11.1-1.1-1.00.91.10.11.5-1.6
Incentive salience index mean1.21.53.51.9-1.10.9-0.90.71.3-1.4-0.7-1.80.9-1.1
Condit. Reinf. lever presses1.51.94.42.0-1.31.2-1.21.01.4-1.5-1.1-2.10.9-1.0
Condit. Reinf. active minus inactive responses0.70.83.10.30.7-0.60.6-0.9-0.40.30.4-0.91.8-1.7
Condit. Reinf. active-inactive response ratio0.20.30.90.50.10.1-0.1-0.10.1-0.1-0.1-0.90.9-0.9
Condit. Reinf. active responses1.41.93.4-0.81.6-1.61.6-1.9-1.31.21.40.21.5-1.4
Condit. Reinf. inactive responses1.41.83.0-1.21.5-1.71.7-1.7-1.21.11.51.20.5-0.5
Condit. Reinf. lever presses0.10.10.3-0.20.1-0.50.5-0.4-0.30.10.50.60.0-0.0
Condit. Reinf. lever reinforcers received0.81.21.9-0.51.2-1.21.2-1.4-1.00.81.10.01.4-1.3
Conditioned reinforcement - actives2.42.43.4-1.81.6-1.71.7-1.7-1.81.91.81.20.5-0.4
Conditioned reinforcement - inactives2.42.74.5-2.11.4-1.71.7-1.6-1.92.01.82.00.10.2
Conditioned locomotion1.41.73.9-2.01.3-1.21.2-1.1-1.31.51.41.3-0.80.9
Patch foraging indifference point 0 sec0.10.20.8-0.20.3-0.20.2-0.10.3-0.2-0.00.4-0.90.9
Patch foraging indifference point AUC1.01.22.91.4-0.71.0-1.00.81.3-1.4-1.1-1.70.1-0.1
Delay disc. indifference point, 0s delay0.91.04.70.8-0.10.1-0.1-0.1-0.20.4-0.3-1.22.0-2.2
Delay disc. indifference point, 16s delay0.00.00.1-0.20.1-0.20.2-0.1-0.20.10.20.2-0.20.1
Delay disc. indifference point, 2s delay0.20.30.70.4-0.70.7-0.70.80.3-0.1-0.8-0.3-0.20.1
Delay disc. indifference point, 24s delay0.90.92.31.5-0.70.8-0.80.51.3-1.3-0.7-0.70.5-0.7
Delay disc. indifference point, 4s delay0.50.51.70.9-0.40.3-0.30.20.4-0.2-0.6-1.11.1-1.3
Delay disc. indifference point, 8s delay2.22.33.31.7-1.81.7-1.71.71.7-1.6-1.8-1.1-0.40.3
Indifference point function ln k1.41.92.6-1.61.4-1.51.5-1.5-1.61.61.51.50.3-0.3
Indifference point function log k1.41.92.6-1.61.4-1.51.5-1.5-1.61.61.51.50.3-0.3
Patch foraging total patch changes 0 sec0.10.20.9-0.30.4-0.30.3-0.20.2-0.20.10.5-0.90.9
Patch foraging total patch changes 12 sec1.21.62.31.3-1.11.3-1.31.41.5-1.4-1.5-1.0-0.90.8
Patch foraging total patch changes 18 sec0.20.30.40.6-0.60.6-0.60.60.6-0.6-0.5-0.1-0.40.3
Patch foraging total patch changes 24 sec0.30.31.60.60.00.2-0.2-0.00.7-0.9-0.5-1.30.2-0.1
Patch foraging total patch changes 6 sec0.71.12.30.9-0.60.8-0.80.81.5-1.5-1.0-0.6-1.31.3
Patch foraging time to switch 0 sec0.81.22.01.1-1.31.4-1.41.41.0-0.9-1.3-0.8-0.40.3
Patch foraging water rate 0 sec0.30.50.8-0.60.7-0.90.9-0.9-0.60.70.80.40.3-0.3
Patch foraging water rate 12 sec0.60.91.8-1.00.8-1.11.1-1.1-0.90.71.21.3-0.00.1
Patch foraging water rate 18 sec1.11.52.6-1.11.4-1.61.6-1.4-1.21.11.30.90.7-0.6
Patch foraging water rate 24 sec1.52.03.1-0.81.5-1.81.8-1.7-1.31.21.70.31.4-1.4
Patch foraging water rate 6 sec0.20.20.5-0.70.2-0.40.4-0.3-0.30.20.50.7-0.60.6
Seeking ratio, delayed vs. immediate footshock0.10.10.50.10.2-0.10.1-0.4-0.10.20.2-0.30.7-0.6
Distance traveled before self-admin0.30.40.90.9-0.30.5-0.50.30.6-0.5-0.4-0.90.6-0.7
Distance traveled after self-admin0.30.41.6-0.7-0.1-0.00.00.4-0.80.80.21.3-0.40.5
Extensor digitorum longus weight0.62.37.40.21.1-1.11.1-1.6-0.80.70.9-1.52.7-2.7
Bone: elastic displacement2.83.25.50.9-2.22.1-2.12.41.4-1.3-2.10.1-1.91.8
Bone: elastic work1.62.13.70.3-1.81.6-1.61.90.9-0.7-1.80.6-1.81.7
Bone: endosteal estimation4.39.312.9-3.63.6-3.53.5-3.4-3.33.23.32.90.3-0.1
Bone: endosteal perimeter4.810.014.0-3.73.6-3.63.6-3.4-3.53.43.63.10.3-0.1
Epididymis fat weight0.20.51.40.10.5-0.70.7-0.6-0.50.40.90.21.2-1.1
Delta time in closed arm before/after self-admin0.50.51.81.10.00.3-0.30.10.9-1.0-0.2-1.30.3-0.5
Delta time in open arm before/after self-admin0.10.10.20.2-0.30.4-0.40.4-0.10.4-0.4-0.20.4-0.4
Diff in mean of infusions in LGA sessions0.30.41.10.10.6-0.60.6-0.6-0.40.30.6-0.40.9-1.0
Delay discount exponential model param0.50.61.1-1.00.8-0.70.7-0.7-0.80.70.80.9-0.40.5
Extinction: sum of active levers before priming0.40.40.6-0.10.7-0.70.7-0.8-0.30.40.7-0.40.7-0.8
Active lever presses in extinction session 61.31.32.7-0.61.1-0.90.9-0.9-1.41.50.90.01.6-1.6
Bone: final force0.91.52.8-1.21.6-1.71.7-1.7-1.00.91.30.70.4-0.2
Bone: final moment0.91.42.6-1.31.5-1.61.6-1.5-1.00.91.21.1-0.10.2
Food consumed during 24 hour testing period0.10.10.40.3-0.1-0.20.2-0.10.3-0.60.2-0.0-0.30.2
Glucose0.10.20.5-0.30.6-0.60.6-0.7-0.1-0.10.4-0.00.2-0.1
Heart weight0.50.73.0-0.40.3-0.20.2-0.00.4-0.70.20.9-1.71.7
Delay discount hyperbolic model param0.50.61.0-1.00.8-0.80.8-0.8-0.80.60.90.8-0.20.3
Intermittent access intake day 1-15 change2.92.86.4-2.52.0-1.81.8-1.7-1.81.81.70.9-0.80.9
Intermittent access intake escalation2.92.86.5-2.51.9-1.71.7-1.6-1.81.71.61.0-1.11.2
Intermittent access intake escalation 21.21.23.0-1.71.4-1.01.0-1.0-1.21.20.90.3-0.80.9
Intermitt. access day 1 inactive lever presses0.40.42.6-0.3-0.50.3-0.30.50.1-0.1-0.31.6-0.80.8
Intermitt. access day 15 inactive lever presses2.42.610.1-2.11.0-1.11.1-0.8-1.51.61.23.2-1.31.5
Intermitt. access escalation Index0.20.20.70.8-0.00.3-0.30.10.3-0.4-0.3-0.10.7-0.8
Intermittent access day 1 total infusions1.01.11.6-0.81.0-1.11.1-1.1-1.31.21.20.91.0-0.9
Intermittent access day 15 total infusions5.05.68.5-2.92.7-2.72.7-2.7-2.62.52.72.10.10.1
Intermittent access terminal intake (last 3 days)2.93.25.3-2.32.0-1.91.9-1.8-2.12.01.91.7-0.10.3
Intermittent access total infusions2.32.63.7-1.71.7-1.71.7-1.8-1.91.81.81.40.7-0.5
Intermittent access day 1 locomotion0.50.50.9-0.60.6-0.80.8-0.9-0.70.70.90.60.6-0.5
Intermittent access day 15 total locomotion1.71.83.8-1.91.3-1.41.4-1.2-1.41.51.41.5-0.70.8
Intermittent access total locomotion0.30.40.8-0.70.5-0.50.5-0.6-0.90.90.70.50.4-0.4
Intermittent access standard deviation1.71.82.8-1.71.6-1.51.5-1.4-1.31.11.51.4-0.50.6
Left kidney weight0.51.33.1-0.51.6-1.61.6-1.8-0.50.31.30.20.9-0.9
Right kidney weight0.20.61.40.21.1-0.90.9-1.20.4-0.60.6-0.80.5-0.5
Cocaine induced anxiety0.50.61.20.9-0.50.7-0.70.50.3-0.2-0.6-1.11.1-1.1
Post-drug Anxiety0.40.40.90.5-0.80.9-0.91.00.4-0.3-0.8-0.1-0.10.1
Baseline Anxiety0.20.21.1-0.3-0.20.0-0.00.20.1-0.1-0.10.4-1.01.0
Tail length0.41.32.9-0.41.4-1.31.3-1.7-0.70.51.1-0.61.4-1.2
Length with tail1.24.38.4-1.22.6-2.62.6-2.9-1.71.42.30.32.0-1.8
Length without tail1.83.96.1-0.82.2-2.32.3-2.4-1.61.52.10.12.5-2.5
Times rat made contact with spout0.30.41.40.7-0.80.4-0.40.4-0.10.1-0.1-0.21.0-1.2
Lifetime Intake1.82.13.2-1.61.6-1.61.6-1.5-1.81.61.61.40.5-0.4
Liver weight, left2.74.36.8-1.32.2-2.42.4-2.6-1.91.82.30.72.1-2.0
Liver weight, right0.91.63.9-0.11.3-1.01.0-1.4-0.90.81.0-1.12.0-1.9
Locomotor activity0.40.61.00.6-0.90.9-0.91.00.7-0.7-0.8-0.4-0.70.6
Locomotor testing distance0.60.91.30.7-1.01.1-1.11.11.0-1.0-1.0-0.3-1.00.9
Locomotor testing rearing0.10.20.60.10.5-0.20.2-0.2-0.30.20.2-0.20.7-0.8
Locomotion in novel chamber1.21.52.6-1.61.2-1.21.2-1.1-1.61.61.21.40.3-0.3
Locomotion in novel chamber post-restriction2.32.74.0-1.12.0-1.81.8-2.0-1.61.41.80.51.8-1.7
Fecal boli incidents, locomotor time 10.20.21.00.20.0-0.00.0-0.0-0.10.4-0.0-0.11.0-1.0
Change in fecal boli incidents, locomotor task0.10.10.30.1-0.10.1-0.10.00.3-0.5-0.2-0.3-0.40.4
Time >=10cm from walls, locomotor time 13.23.36.8-1.02.2-2.12.1-2.6-1.41.21.7-0.02.1-1.9
Bouts of movement, locomotor time 10.40.51.0-0.60.8-0.50.5-0.6-0.81.00.60.90.6-0.4
Total resting periods, locomotor time 10.50.61.2-0.70.8-0.60.6-0.7-0.91.10.60.90.8-0.6
Rest time, locomotor task time 10.20.20.7-0.6-0.10.3-0.30.3-0.50.8-0.10.8-0.10.2
Distance moved, locomotor task time 10.70.82.91.2-0.30.1-0.1-0.21.0-1.3-0.6-1.70.7-0.8
Vertical activity count, locomotor time 10.10.10.30.20.1-0.50.5-0.30.3-0.40.10.0-0.20.1
Time >=10cm from walls, locomotor time 20.70.82.70.50.5-0.30.3-0.7-0.0-0.1-0.1-1.51.7-1.6
Bouts of movement, locomotor time 21.82.03.51.7-1.61.8-1.81.91.2-1.0-1.5-1.10.1-0.1
Total resting periods, locomotor time 21.92.03.31.7-1.61.8-1.81.81.2-1.0-1.6-1.30.3-0.3
Rest time, locomotor task time 20.20.21.00.20.00.2-0.2-0.1-0.10.3-0.2-0.51.0-1.0
Distance moved, locomotor task time 20.20.20.80.40.1-0.30.3-0.50.3-0.5-0.0-0.90.5-0.7
Vertical activity count, locomotor time 20.20.20.60.3-0.60.2-0.20.50.5-0.5-0.40.3-0.80.7
Light reinforcement 10.20.51.5-1.00.3-0.20.2-0.0-0.81.10.21.2-0.40.5
Light reinforcement 22.53.36.51.0-2.32.3-2.32.51.4-1.1-2.2-0.1-1.61.5
Bone: marrow area4.59.713.8-3.73.6-3.63.6-3.4-3.43.33.43.00.3-0.0
Bone: maximum diameter7.914.619.6-4.24.4-4.44.4-4.3-4.24.14.43.31.1-0.8
Bone: maximum force2.23.96.0-2.22.4-2.42.4-2.4-1.91.82.21.70.10.1
Bone: maximum moment2.23.75.6-2.42.2-2.32.3-2.2-1.81.72.02.0-0.40.6
Mean time between licks in bursts1.01.42.80.6-1.01.0-1.01.01.4-1.4-1.10.2-1.71.7
Mean num. licks in bursts1.41.72.4-1.51.4-1.51.5-1.5-1.51.51.30.60.6-0.6
Cd content in liver0.30.31.10.2-0.20.3-0.30.20.7-0.8-0.20.1-1.01.1
Co content in liver1.41.64.6-0.1-1.11.0-1.01.40.7-0.6-0.91.2-2.12.1
Cu content in liver2.83.45.20.8-2.12.0-2.02.31.6-1.5-2.00.1-2.32.2
Fe content in liver3.74.47.02.2-2.22.2-2.22.12.6-2.5-2.6-1.6-1.11.0
K content in liver1.01.01.61.1-1.11.1-1.11.00.4-0.2-1.1-1.31.0-1.0
Mg content in liver1.51.62.11.4-1.41.5-1.51.41.2-1.1-1.5-1.40.0-0.1
Mn content in liver1.61.82.61.6-1.51.5-1.51.51.5-1.4-1.5-1.4-0.10.1
Na content in liver2.42.55.02.2-1.81.7-1.71.61.4-1.3-1.7-1.61.0-1.1
Rb content in liver0.20.31.10.10.2-0.10.1-0.3-0.10.10.1-1.10.8-0.9
Se content in liver20.124.632.64.9-5.65.5-5.55.75.7-5.6-5.6-3.3-3.12.8
Sr content in liver1.11.03.5-1.30.3-0.30.3-0.0-0.60.60.41.9-1.51.6
Zn content in liver8.89.813.33.6-3.53.5-3.53.43.5-3.4-3.6-2.9-0.70.5
Bone: minimum diameter7.213.421.1-3.74.5-4.54.5-4.6-3.53.34.32.71.3-1.0
Time in familiar zone, hab. session 10.30.21.0-0.50.0-0.10.10.0-0.30.30.21.0-0.80.7
Time in novel zone, hab. session 10.60.61.50.9-0.70.8-0.80.60.8-0.8-0.8-1.20.4-0.3
Total zone transitions, hab. session 10.00.10.3-0.3-0.1-0.10.1-0.0-0.30.20.30.5-0.10.2
Total locomotion distance, hab. session 10.60.82.01.1-1.41.0-1.01.10.8-0.8-1.1-0.40.2-0.3
Locomotion velocity, hab. session 10.91.32.51.5-1.61.3-1.31.31.0-1.0-1.3-0.90.4-0.5
Time in familiar zone, hab. session 20.40.41.20.1-0.70.5-0.50.70.4-0.4-0.40.5-1.11.0
Time in novel zone, hab. session 20.00.00.1-0.20.3-0.20.2-0.2-0.10.10.0-0.10.1-0.1
Total zone transitions, hab. session 20.40.51.10.4-0.50.5-0.50.50.8-1.1-0.5-0.7-0.91.0
Total locomotion distance, hab. session 20.50.61.20.8-0.90.7-0.70.81.0-1.1-1.0-0.6-0.40.4
Locomotion velocity, hab. session 20.50.71.11.0-0.90.8-0.80.81.0-1.0-1.1-0.90.0-0.0
Novel to familiar place preference ratio0.60.61.6-0.70.5-0.50.5-0.5-1.01.30.40.70.9-0.9
Novelty place preference0.70.71.9-0.90.6-0.60.6-0.5-1.11.40.40.90.8-0.8
Time in novel zone, NPP test0.40.51.3-0.70.4-0.40.4-0.4-0.91.10.30.70.8-0.8
Total zone transitions, NPP test0.60.81.61.3-0.90.8-0.80.71.1-1.2-0.7-1.30.2-0.1
Total locomotion distance, NPP test1.52.13.51.9-1.91.5-1.51.51.5-1.6-1.6-1.20.1-0.3
Locomotion velocity, NPP test1.42.03.71.9-1.81.4-1.41.41.4-1.5-1.5-1.40.5-0.6
Intraocular pressure0.30.51.5-1.00.3-0.60.6-0.6-0.80.70.51.2-0.40.5
Delta distance traveled before/after self-admin1.41.53.6-1.70.7-1.11.1-0.7-1.61.71.21.9-0.20.3
Delta ambulatory time before/after self-admin2.32.54.4-2.01.1-1.61.6-1.1-2.02.11.72.10.20.0
Parametrial fat weight0.30.61.3-0.31.1-0.80.8-1.1-0.60.40.80.20.8-0.8
Pavlov. Cond. lever latency0.91.23.4-1.60.7-0.60.6-0.4-0.50.60.41.4-1.71.8
Pavlov. Cond. magazine entry latency0.91.22.91.7-1.10.9-0.90.81.4-1.7-0.8-1.20.2-0.4
Pavlov. Cond. change in total contacts1.01.12.71.6-1.00.9-0.90.71.5-1.7-0.8-1.1-0.1-0.0
Pavlov. Cond. index score1.01.33.21.8-0.70.6-0.60.30.9-1.1-0.3-1.61.5-1.6
Pavlov. Cond. latency score1.21.64.11.9-0.70.5-0.50.20.8-0.9-0.3-1.81.9-2.0
Pavlov. Cond. lever contacts1.21.43.11.8-0.80.7-0.70.40.8-1.0-0.5-1.71.6-1.8
Pavlov. Cond. magazine entry number0.30.31.1-1.00.5-0.30.3-0.2-0.81.10.10.50.00.1
Pavlov. Cond. intertrial magazine entries0.40.50.9-0.40.6-0.80.8-0.8-0.70.80.70.11.0-0.9
Pavlov. Cond. lever-magazine prob. diff.1.31.64.12.0-1.00.8-0.80.51.2-1.4-0.6-1.71.4-1.5
Pavlov. Cond. response bias0.81.02.41.6-1.10.9-0.90.81.3-1.6-0.7-0.90.1-0.2
Pavlov. Cond. lever latency0.20.21.00.10.3-0.10.1-0.2-0.40.40.1-0.41.0-1.0
Pavlov. Cond. magazine entry latency0.60.71.51.2-0.90.8-0.80.71.1-1.1-0.7-1.00.1-0.2
Pavlov. Cond. change in total contacts0.20.30.60.8-0.60.3-0.30.20.5-0.6-0.2-0.70.5-0.6
Pavlov. Cond. index score0.10.10.20.5-0.30.1-0.10.00.4-0.5-0.0-0.40.2-0.2
Pavlov. Cond. latency score0.00.00.10.3-0.1-0.10.1-0.10.2-0.30.2-0.30.3-0.2
Pavlov. Cond. lever contacts0.10.10.3-0.1-0.1-0.10.1-0.00.3-0.30.00.1-0.50.5
Pavlov. Cond. magazine entry number1.41.73.2-1.81.4-1.31.3-1.1-1.61.71.21.5-0.10.2
Pavlov. Cond. intertrial magazine entries0.91.12.4-0.41.0-1.01.0-1.1-1.01.01.00.11.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.7-0.40.2-0.20.10.5-0.6-0.1-0.70.4-0.4
Pavlov. Cond. response bias0.40.61.31.0-0.80.7-0.70.61.0-1.1-0.6-0.8-0.20.1
Time in closed arm before self-admin0.20.20.60.2-0.70.7-0.70.8-0.0-0.1-0.60.00.2-0.2
Time in closed arm after self-admin1.41.53.21.8-0.90.9-0.90.81.0-1.2-0.9-1.81.3-1.4
Time in open arm before self-admin0.20.20.9-0.2-0.2-0.10.10.10.2-0.00.10.5-0.90.9
Time in open arm after self-admin0.70.71.9-1.20.5-0.60.6-0.4-1.01.30.71.4-0.50.6
Bone: periosteal estimation5.210.715.3-3.63.9-3.93.9-3.8-3.43.33.72.80.8-0.6
Bone: periosteal perimeter4.98.111.7-2.83.3-3.43.4-3.4-3.02.93.32.11.3-1.1
Bone: post-yield work3.04.17.9-1.92.7-2.52.5-2.7-1.71.42.81.00.6-0.4
Progressive ratio test 1 active lever presses1.51.62.5-1.51.2-1.41.4-1.3-1.61.61.50.60.3-0.2
Progressive ratio test 1 breakpoint1.41.42.4-1.51.1-1.41.4-1.1-1.61.51.40.70.2-0.1
Progressive ratio test 1 inactive lever presses2.32.54.6-2.01.2-1.51.5-1.3-2.02.11.62.10.2-0.1
Progressive ratio test 2 active lever presses4.54.88.0-2.82.6-2.42.4-2.4-2.52.52.51.40.10.0
Progressive ratio test 2 breakpoint5.36.09.8-3.12.8-2.72.7-2.7-2.92.92.71.60.2-0.0
Progressive ratio test 2 inactive lever presses2.42.75.4-2.31.4-1.51.5-1.3-2.12.11.52.3-0.30.4
Incentive Sensitization - Responses4.64.78.1-2.82.6-2.22.2-2.2-2.52.52.32.1-0.00.2
Incentive Sensitization - Breakpoint4.84.98.3-2.92.6-2.32.3-2.3-2.52.62.32.3-0.00.2
Sum of active levers in priming session hrs 5-60.50.51.00.1-0.40.9-0.91.00.2-0.1-0.80.4-1.00.8
Progressive ratio0.60.71.8-0.10.8-0.80.8-1.0-0.50.30.70.31.3-1.3
Food seeking constrained by brief footshock2.43.05.7-1.52.1-2.22.2-2.4-1.41.32.20.90.9-0.7
Seeking ratio, punishment vs. effort0.10.10.3-0.30.2-0.30.3-0.30.10.00.3-0.2-0.50.6
Retroperitoneal fat weight0.10.40.9-0.40.8-0.80.8-0.8-0.70.30.90.10.5-0.4
Reaction time number correct0.91.32.7-1.21.2-1.01.0-1.1-1.51.61.20.30.9-0.8
Reaction time mean minus median0.70.93.1-1.10.4-0.60.6-0.5-0.30.50.71.8-1.31.3
Reaction time mean minus median AUC0.50.72.5-0.6-0.3-0.00.00.20.20.00.01.4-1.61.6
Reaction time num false alarms0.81.03.10.01.1-0.80.8-1.0-0.60.70.5-1.01.7-1.7
Reaction time num false alarms AUC0.50.72.20.20.9-0.60.6-0.9-0.30.30.3-1.11.5-1.4
Reaction time trials correct on left0.91.32.7-1.21.2-1.01.0-1.1-1.51.61.20.30.9-0.8
Reaction time trials on left0.91.22.6-1.11.2-1.01.0-1.1-1.51.61.20.30.9-0.8
Reaction time mean1.42.03.31.0-1.51.4-1.41.31.8-1.7-1.3-0.2-1.61.6
Reaction time mean AUC1.92.54.01.1-1.71.6-1.61.62.0-1.8-1.5-0.3-1.81.7
Median of all reaction times2.23.14.91.4-1.91.8-1.81.82.2-2.1-1.9-0.7-1.61.6
Reaction time omissions0.10.10.30.1-0.00.0-0.0-0.10.5-0.4-0.2-0.3-0.40.4
Reaction time false alarm rate0.20.31.00.50.4-0.30.3-0.50.2-0.2-0.0-0.91.0-0.9
Reaction time premature initiation rate1.21.62.4-1.01.3-1.51.5-1.4-1.31.21.61.10.9-0.7
Reaction time premature initiations2.83.95.7-1.82.1-2.22.2-2.2-2.22.32.41.31.4-1.2
Std. dev. reaction times0.60.93.5-0.2-0.40.1-0.10.20.7-0.7-0.11.1-1.91.9
Reaction time trials completed0.91.22.6-1.11.2-1.01.0-1.1-1.51.61.20.30.9-0.8
Reaction time trials AUC0.60.91.9-0.80.9-0.70.7-0.8-1.31.41.0-0.01.0-0.9
Run reversals in cocaine runway, females0.60.51.2-0.0-1.10.7-0.71.00.1-0.0-0.60.6-1.01.0
Run reversals in cocaine runway, males0.10.10.50.4-0.00.1-0.1-0.10.4-0.60.1-0.70.1-0.1
Latency to leave start box in cocaine runway0.40.40.8-0.60.9-0.80.8-0.8-0.60.80.40.40.4-0.4
Latency to leave start box in cocaine runway, F0.10.10.3-0.20.5-0.30.3-0.4-0.30.30.0-0.20.3-0.2
Latency to leave start box in cocaine runway, M0.60.61.0-0.70.8-1.01.0-0.9-0.60.90.61.00.3-0.3
Std. dev. time between licks in bursts2.02.43.41.3-1.51.7-1.71.61.9-1.8-1.60.1-1.51.5
Total sessions with >9 infusions0.50.61.0-1.00.7-0.80.8-0.6-1.00.90.90.8-0.20.3
Short access day 1 total inactive lever presses1.51.76.0-1.90.5-0.60.6-0.2-1.41.60.72.4-1.21.4
Short access day 10 total inactive lever presses0.91.02.00.8-1.41.2-1.21.40.7-0.6-1.2-0.4-0.40.4
Short access day 1 total infusions0.00.00.1-0.20.1-0.10.1-0.1-0.30.20.20.2-0.20.2
Short access day 10 total infusions0.20.21.4-0.40.1-0.30.3-0.2-0.30.20.31.2-0.30.4
Short access total infusions0.91.01.7-1.21.0-1.11.1-1.0-1.31.21.11.00.3-0.1
Short access day 1 locomotion0.10.10.60.1-0.00.0-0.00.1-0.10.3-0.0-0.80.0-0.1
Short access day 10 total locomotion0.10.20.50.5-0.70.5-0.50.50.3-0.3-0.4-0.1-0.0-0.1
Short access total locomotion0.20.20.60.3-0.80.6-0.60.70.3-0.2-0.5-0.2-0.40.4
One hour access (0.3 mA shock)8.29.613.6-3.73.6-3.53.5-3.4-3.63.53.52.10.7-0.5
Compulsive drug intake0.90.91.6-0.71.0-1.11.1-1.3-0.90.81.01.00.8-0.7
One hour access (shock baseline)2.22.64.5-2.11.8-1.71.7-1.6-2.01.91.81.00.00.0
Social response proportion0.20.20.5-0.70.10.2-0.20.4-0.60.70.10.6-0.60.6
Social responses1.01.22.9-1.71.1-0.80.8-0.7-1.31.31.01.2-1.01.2
Social time0.50.61.00.8-0.80.9-0.90.91.0-0.9-0.7-0.7-0.40.5
Soleus weight0.92.65.5-2.11.5-1.71.7-1.5-1.61.61.72.3-0.60.7
Bone: stiffness2.94.57.9-1.62.7-2.62.6-2.8-2.01.82.50.11.7-1.5
Tibialis anterior weight0.93.011.30.30.8-0.90.9-1.3-1.11.10.9-1.73.4-3.3
Time to tail flick, vehicle, before self-admin0.91.02.00.4-1.31.1-1.11.40.6-0.4-1.10.5-1.01.0
Time to tail flick, vehicle, after self-admin1.21.35.00.10.5-0.60.6-0.9-0.70.90.6-0.82.2-2.2
Time to tail flick, test, before self-admin2.02.02.6-1.01.3-1.51.5-1.5-1.51.41.50.81.6-1.6
Time to tail flick, test, after self-admin0.30.30.60.5-0.70.8-0.80.70.3-0.3-0.7-0.6-0.0-0.0
Delta time to tail flick, vehicle, before/after SA3.93.910.1-0.51.8-1.81.8-2.2-1.61.51.8-0.93.2-3.1
Delta time to tail flick, test, before/after SA0.30.20.80.4-0.30.6-0.60.40.4-0.3-0.5-0.9-0.20.1
Tibia length0.10.30.6-0.50.8-0.70.7-0.8-0.20.10.60.3-0.30.3
Ambulatory time before self-admin1.01.12.71.4-0.81.0-1.00.91.1-1.0-1.0-1.60.2-0.3
Ambulatory time after self-admin0.40.41.3-0.70.1-0.20.20.2-0.91.10.41.1-0.00.1
Bone: tissue strength0.50.52.2-0.4-0.10.1-0.10.20.3-0.40.00.6-1.41.5
Total heroin consumption0.91.11.6-1.01.3-1.11.1-1.0-1.31.31.10.50.6-0.7
Bone: trabecular number5.38.316.0-3.72.8-3.13.1-2.6-3.23.32.74.0-0.50.6
Bone: trabecular spacing2.53.28.42.4-1.51.7-1.71.42.0-2.1-1.5-2.90.4-0.5
Bone: trabecular thickness4.55.310.7-2.82.3-2.62.6-2.3-2.42.52.13.3-0.00.1
Bone: trabecular tissue density1.21.73.4-1.31.2-1.31.3-1.1-1.81.81.50.90.9-0.8
Water consumed over 24 hours0.91.02.41.4-1.00.7-0.70.60.5-0.5-0.8-1.31.4-1.5
Number of responses in last shaping day1.81.83.8-2.01.6-1.41.4-1.3-1.51.51.50.9-0.40.4