Hub : Genes

Coq10b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_039083296.1 0.13 0.11 6.7e-03 0.03 0.02 0.02 0.03 5.1e-04 1.1e-02 7.4e-03 5.7e-04
2 Brain alternative TSS NM_001009671.1 0.17 0.12 7.6e-03 0.03 0.01 0.01 0.03 9.0e-04 1.2e-02 2.0e-02 1.1e-03
3 Brain gene expression Coq10b 0.14 0.07 2.1e-14 0.14 0.13 0.14 0.14 6.3e-13 7.7e-12 2.1e-13 7.3e-13
4 BLA gene expression Coq10b 0.06 0.04 1.7e-03 0.04 0.05 0.04 0.04 4.9e-03 1.5e-03 2.1e-03 2.1e-03
5 Adipose mRNA stability Coq10b 0.02 0.01 7.2e-03 0.01 0.01 0.01 0.01 2.3e-02 1.1e-02 3.2e-02 3.4e-02
6 NAcc mRNA stability Coq10b 0.04 0.04 2.2e-03 0.02 0.02 0.02 0.02 1.9e-03 4.8e-03 5.0e-03 5.5e-03
7 BLA isoform ratio XM_039083296.1 0.07 0.05 1.9e-03 0.04 0.03 0.02 0.03 4.8e-03 7.1e-03 4.3e-02 1.2e-02
8 pVTA gene expression Coq10b 0.14 0.1 7.3e-05 0.1 0.09 0.09 0.09 3.6e-05 1.2e-04 1.0e-04 9.4e-05
9 LHb gene expression Coq10b 0.79 0.16 1.1e-04 0.1 0.06 0.05 0.07 2.6e-03 1.7e-02 2.3e-02 8.5e-03
10 Adipose gene expression Coq10b 0.05 0.04 1.8e-05 0.04 0.04 0.04 0.04 1.4e-05 5.2e-05 2.2e-05 2.2e-05
11 PL gene expression Coq10b 0.06 0.04 1.9e-06 0.05 0.04 0.04 0.05 2.9e-06 6.6e-05 2.1e-05 6.8e-06
12 BLA isoform ratio NM_001009671.1 0.07 0.06 2.2e-03 0.04 0.03 0.02 0.03 5.0e-03 7.3e-03 4.3e-02 1.3e-02
13 NAcc gene expression Coq10b 0.03 0.02 1.1e-03 0.01 0.01 0.01 0.01 1.6e-02 1.7e-02 3.0e-02 4.0e-02
14 Brain isoform ratio XM_039083296.1 0.05 0.04 1.0e-04 0.04 0.04 0.04 0.04 1.5e-04 5.4e-05 1.3e-04 9.1e-05
15 Brain isoform ratio NM_001009671.1 0.05 0.04 1.0e-04 0.04 0.04 0.04 0.04 2.1e-04 5.9e-05 1.8e-04 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density6.510.914.23.2-3.22.9-3.1-3.73.83.33.33.33.33.3-3.33.3-3.33.3
Area under the delay curve0.10.10.2-0.20.2-0.50.40.1-0.0-0.3-0.3-0.4-0.3-0.40.3-0.3-0.20.2
BMI with tail3.712.013.7-3.23.2-3.63.73.6-3.6-3.6-3.6-3.7-3.6-3.73.7-3.72.7-2.7
BMI without tail0.20.41.3-1.01.00.20.00.6-0.50.20.20.20.20.1-0.00.01.1-1.1
Body weight1.04.05.82.1-2.12.4-2.3-1.81.72.22.22.12.21.9-2.12.1-1.11.1
Weight adjusted by age0.70.71.41.1-1.10.5-0.7-1.11.10.60.60.70.60.8-0.60.6-1.21.2
Bone surface6.211.014.03.2-3.23.0-3.2-3.73.73.33.33.33.33.3-3.33.3-3.23.2
Bone volume6.611.315.23.3-3.32.9-3.1-3.83.93.33.33.33.33.3-3.33.3-3.53.5
Breakpoint value in progressive ratio session0.10.10.20.5-0.5-0.0-0.0-0.1-0.1-0.2-0.2-0.2-0.2-0.20.2-0.2-0.40.4
Number of licking bursts0.70.81.2-0.40.4-1.11.00.7-0.7-1.1-1.1-1.1-1.1-1.11.1-1.10.2-0.2
Context. condit. distance diff. score1.11.42.9-1.41.4-0.70.91.5-1.5-0.9-0.9-0.9-0.9-0.90.8-0.81.7-1.7
Locomotion velocity, session 11.11.23.5-1.91.9-1.11.21.0-0.7-0.8-0.8-0.8-0.8-0.80.9-0.90.9-0.9
Locomotion distance, session 10.20.31.1-1.01.0-0.40.40.6-0.4-0.2-0.2-0.2-0.20.00.3-0.30.7-0.7
Locomotion velocity, session 20.60.72.5-1.61.6-1.01.00.7-0.4-0.6-0.6-0.6-0.6-0.60.7-0.70.5-0.5
Locomotion distance, session 20.10.20.4-0.60.6-0.30.40.5-0.5-0.2-0.2-0.2-0.2-0.20.4-0.40.5-0.5
Locomotion velocity, session 30.30.30.6-0.30.30.7-0.50.2-0.20.50.50.60.50.8-0.50.50.8-0.8
Locomotion distance, session 30.00.00.2-0.30.30.1-0.00.2-0.2-0.0-0.00.0-0.00.1-0.00.00.4-0.4
Stereotopy head waving bouts, day 31.21.43.2-1.61.6-0.60.81.5-1.5-0.8-0.8-0.8-0.8-0.70.9-0.91.8-1.8
Stereotopy head waving duration, day 30.30.31.4-0.80.80.2-0.00.7-0.70.10.10.10.10.2-0.00.01.2-1.2
Locomotion velocity, session 70.70.82.7-1.71.7-1.11.00.6-0.3-0.6-0.6-0.6-0.6-0.60.6-0.60.5-0.5
Locomotion distance, session 70.00.10.1-0.40.4-0.40.30.10.0-0.2-0.2-0.2-0.2-0.30.2-0.20.0-0.0
Stereotopy head waving bouts, day 70.20.20.40.0-0.00.3-0.3-0.50.60.50.50.50.50.6-0.40.4-0.40.4
Stereotopy head waving duration, day 70.10.10.3-0.40.40.3-0.3-0.20.30.50.50.50.50.6-0.40.40.1-0.1
Locomotion velocity, session 80.60.71.7-1.21.2-1.31.20.5-0.2-0.9-0.9-0.8-0.9-0.80.9-0.9-0.00.0
Locomotion distance, session 81.01.52.9-1.71.7-0.91.01.5-1.4-0.9-0.9-0.9-1.0-0.70.9-0.91.6-1.6
Degree of sensitization distance0.20.20.70.4-0.4-0.30.1-0.40.5-0.1-0.1-0.1-0.1-0.30.1-0.1-0.80.8
Degree of sensitization stereotypy0.20.30.70.3-0.30.1-0.2-0.70.80.40.40.40.40.4-0.30.3-0.80.9
Conditioned locomotion1.41.64.12.0-2.01.2-1.2-1.31.01.01.01.01.00.9-1.01.0-1.31.3
Cocaine response after cond. corrected1.71.96.11.7-1.70.3-0.6-1.81.80.70.70.70.70.7-0.80.8-2.52.5
Cocaine response after cond. not corrected2.62.97.31.8-1.80.7-1.0-2.22.21.21.21.21.21.2-1.31.3-2.72.7
Cocaine response before conditioning0.10.10.3-0.50.50.1-0.00.3-0.20.10.10.10.10.2-0.10.10.5-0.5
Saline control response0.20.20.8-0.30.30.00.10.6-0.7-0.3-0.3-0.3-0.3-0.20.3-0.30.9-0.9
Bone: connectivity density3.25.07.12.1-2.11.9-2.0-2.62.72.22.22.22.22.2-2.22.2-2.42.4
Bone: cortical apparent density7.59.911.6-2.72.7-3.23.23.3-3.4-3.4-3.4-3.4-3.4-3.43.4-3.42.4-2.4
Bone: cortical area0.20.30.40.6-0.60.5-0.5-0.50.50.50.50.50.50.6-0.50.5-0.50.5
Bone: cortical porosity5.15.67.42.0-2.02.6-2.6-2.32.32.62.62.62.62.7-2.62.6-1.41.4
Bone: cortical porosity7.27.89.52.6-2.63.0-3.0-2.82.73.03.03.03.03.1-3.03.0-1.91.9
Bone: cortical thickness1.32.22.8-1.21.2-1.51.51.6-1.7-1.6-1.6-1.6-1.6-1.51.6-1.61.2-1.2
Bone: cortical thickness1.61.93.3-0.90.9-1.81.71.0-1.0-1.6-1.6-1.6-1.6-1.51.6-1.60.1-0.1
Bone: cortical tissue density7.710.111.8-2.72.7-3.23.33.3-3.4-3.4-3.4-3.4-3.4-3.43.4-3.42.5-2.5
Condit. Reinf. active minus inactive responses0.40.41.61.1-1.1-0.30.1-0.60.5-0.2-0.2-0.2-0.2-0.30.2-0.2-1.21.2
Condit. Reinf. active-inactive response ratio0.10.10.50.3-0.3-0.40.3-0.30.3-0.2-0.2-0.2-0.2-0.20.2-0.2-0.70.7
Condit. Reinf. active responses1.01.23.61.9-1.90.2-0.4-1.31.10.30.30.30.30.2-0.30.3-1.91.9
Condit. Reinf. inactive responses0.40.41.61.3-1.30.2-0.3-0.70.60.20.20.20.20.1-0.20.2-1.11.1
Incentive salience index mean0.70.83.21.5-1.5-0.30.1-0.90.8-0.2-0.2-0.2-0.2-0.20.2-0.2-1.81.8
Condit. Reinf. lever presses0.50.71.91.4-1.40.2-0.4-1.00.80.20.20.20.20.2-0.30.3-1.41.4
Condit. Reinf. active minus inactive responses3.54.49.43.0-3.01.2-1.5-2.52.31.41.41.41.41.3-1.51.5-3.13.1
Condit. Reinf. active-inactive response ratio1.01.03.91.6-1.6-0.0-0.2-1.21.00.20.20.20.20.1-0.20.2-2.02.0
Condit. Reinf. active responses2.02.87.62.6-2.60.7-0.9-2.01.80.80.80.80.80.8-0.90.9-2.82.8
Condit. Reinf. inactive responses0.20.30.70.6-0.60.2-0.3-0.70.70.30.30.30.30.4-0.40.4-0.80.8
Condit. Reinf. lever presses0.71.02.00.3-0.3-1.41.20.0-0.1-1.1-1.1-1.1-1.1-1.21.1-1.1-1.11.1
Condit. Reinf. lever reinforcers received1.92.78.22.5-2.50.5-0.7-2.01.80.70.70.70.70.6-0.70.7-2.92.9
Conditioned reinforcement - actives0.20.20.4-0.40.40.6-0.30.2-0.20.50.40.50.50.4-0.50.50.7-0.7
Conditioned reinforcement - inactives0.10.10.3-0.00.00.4-0.4-0.20.40.50.50.40.50.3-0.50.50.1-0.0
Conditioned locomotion0.50.61.10.0-0.0-0.70.70.7-0.9-0.9-0.9-0.9-0.9-1.10.9-0.90.3-0.3
Patch foraging indifference point 0 sec1.11.83.9-0.60.6-2.01.80.6-0.6-1.6-1.6-1.6-1.6-1.51.6-1.6-0.50.5
Patch foraging indifference point AUC0.10.10.30.3-0.30.3-0.3-0.40.60.40.40.40.40.3-0.50.5-0.20.2
Delay disc. indifference point, 0s delay1.92.12.7-1.31.3-1.61.61.4-1.4-1.6-1.6-1.6-1.6-1.61.5-1.51.0-0.9
Delay disc. indifference point, 16s delay0.00.00.1-0.10.1-0.30.3-0.10.1-0.2-0.2-0.2-0.2-0.20.2-0.2-0.30.3
Delay disc. indifference point, 2s delay1.51.73.1-0.20.2-1.71.50.7-0.9-1.6-1.6-1.6-1.6-1.81.6-1.6-0.20.2
Delay disc. indifference point, 24s delay0.30.30.6-0.70.7-0.30.40.7-0.6-0.4-0.4-0.4-0.4-0.40.5-0.50.8-0.8
Delay disc. indifference point, 4s delay0.80.81.1-0.90.9-1.11.10.9-0.8-1.0-1.0-1.0-1.0-0.91.0-1.00.5-0.5
Delay disc. indifference point, 8s delay0.30.30.60.1-0.10.5-0.5-0.60.80.70.70.70.70.6-0.70.7-0.40.4
Indifference point function ln k1.52.23.5-0.90.9-1.91.81.0-1.0-1.8-1.8-1.7-1.8-1.71.8-1.80.1-0.1
Indifference point function log k1.52.23.5-0.90.9-1.91.81.0-1.0-1.8-1.8-1.7-1.8-1.71.8-1.80.1-0.1
Patch foraging total patch changes 0 sec1.32.14.2-0.60.6-2.01.80.8-0.8-1.8-1.8-1.7-1.8-1.71.7-1.7-0.30.3
Patch foraging total patch changes 12 sec0.50.71.40.2-0.2-1.21.00.3-0.3-1.1-1.1-1.0-1.1-1.01.0-1.0-0.50.5
Patch foraging total patch changes 18 sec2.12.74.1-2.02.0-2.01.91.5-1.1-1.7-1.7-1.7-1.7-1.71.5-1.51.0-1.0
Patch foraging total patch changes 24 sec0.00.00.0-0.00.0-0.10.0-0.00.10.00.00.10.00.0-0.10.1-0.00.0
Patch foraging total patch changes 6 sec0.40.51.4-0.40.4-1.21.00.3-0.2-0.9-0.9-0.8-0.9-0.70.9-0.9-0.20.3
Patch foraging time to switch 0 sec0.30.50.9-0.40.41.0-0.70.00.00.90.90.90.90.8-0.70.70.8-0.8
Patch foraging water rate 0 sec0.10.10.60.7-0.7-0.1-0.1-0.30.2-0.1-0.1-0.1-0.1-0.1-0.00.0-0.60.6
Patch foraging water rate 12 sec0.91.43.00.1-0.1-1.71.40.2-0.3-1.5-1.5-1.5-1.5-1.51.3-1.3-0.90.9
Patch foraging water rate 18 sec0.40.62.21.5-1.5-0.1-0.1-0.70.3-0.1-0.1-0.1-0.1-0.00.1-0.1-1.31.3
Patch foraging water rate 24 sec0.10.10.3-0.00.00.4-0.4-0.10.10.40.40.40.40.6-0.40.40.1-0.1
Patch foraging water rate 6 sec0.10.10.50.7-0.7-0.20.1-0.0-0.2-0.4-0.4-0.3-0.4-0.30.2-0.2-0.30.3
Seeking ratio, delayed vs. immediate footshock1.61.92.81.7-1.71.2-1.3-1.51.41.31.21.21.21.3-1.21.2-1.41.4
Distance traveled before self-admin2.12.33.31.8-1.81.2-1.4-1.81.81.41.41.31.41.2-1.31.3-1.71.7
Distance traveled after self-admin0.50.61.10.0-0.0-0.80.80.6-0.8-0.9-0.9-1.0-0.9-1.10.9-0.90.2-0.2
Extensor digitorum longus weight1.76.510.8-3.03.0-1.82.13.1-3.0-2.1-2.1-2.1-2.1-2.12.1-2.13.3-3.3
Bone: elastic displacement0.70.81.3-0.00.0-1.11.00.5-0.7-1.1-1.1-1.1-1.1-1.11.1-1.1-0.20.2
Bone: elastic work0.91.22.11.4-1.40.8-0.9-1.31.20.80.80.80.80.9-0.80.8-1.41.4
Bone: endosteal estimation4.810.412.53.4-3.43.0-3.2-3.53.53.23.13.23.23.2-3.23.2-3.13.1
Bone: endosteal perimeter4.49.110.92.9-2.92.9-3.0-3.33.33.13.03.13.13.1-3.03.0-2.82.8
Epididymis fat weight1.84.16.52.1-2.12.5-2.4-1.71.52.22.22.22.22.0-2.32.3-0.90.9
Delta time in closed arm before/after self-admin0.40.41.5-1.11.10.10.10.7-0.50.10.10.10.10.1-0.20.21.2-1.2
Delta time in open arm before/after self-admin5.04.87.52.4-2.41.6-1.9-2.72.71.91.91.91.91.8-1.81.8-2.72.7
Diff in mean of infusions in LGA sessions0.20.31.00.6-0.6-0.0-0.1-0.70.70.10.10.10.10.3-0.30.3-1.01.0
Delay discount exponential model param0.10.10.20.1-0.10.4-0.4-0.10.00.30.30.30.30.4-0.30.30.2-0.2
Extinction: sum of active levers before priming1.00.92.31.5-1.50.9-1.0-1.00.80.70.70.80.70.9-0.70.7-1.01.0
Active lever presses in extinction session 60.40.41.21.1-1.10.4-0.4-0.70.50.20.20.20.20.0-0.20.2-1.11.0
Bone: final force1.83.04.61.9-1.92.1-2.1-1.51.31.81.81.81.81.9-1.81.8-0.80.8
Bone: final moment1.42.23.71.7-1.71.9-1.8-1.21.01.61.61.61.61.6-1.61.6-0.60.6
Food consumed during 24 hour testing period0.10.10.20.4-0.40.5-0.4-0.20.10.30.30.30.30.3-0.30.3-0.00.0
Glucose0.40.62.9-0.30.30.4-0.11.1-1.3-0.2-0.2-0.2-0.2-0.30.2-0.21.7-1.7
Heart weight0.20.20.40.3-0.3-0.60.4-0.0-0.1-0.6-0.6-0.5-0.6-0.50.4-0.4-0.60.6
Delay discount hyperbolic model param0.20.20.40.3-0.30.7-0.6-0.30.20.50.50.50.50.7-0.60.60.1-0.1
Intermittent access intake day 1-15 change0.40.41.1-0.30.3-0.30.50.8-1.1-0.6-0.6-0.5-0.6-0.40.6-0.60.8-0.8
Intermittent access intake escalation0.30.30.9-0.20.2-0.30.40.7-0.9-0.5-0.5-0.4-0.5-0.40.5-0.50.7-0.7
Intermittent access intake escalation 20.10.10.30.5-0.50.3-0.3-0.1-0.10.10.10.30.10.4-0.10.1-0.10.1
Intermitt. access day 1 inactive lever presses1.01.12.2-1.01.0-0.60.81.4-1.4-0.7-0.7-0.9-0.7-0.90.7-0.71.5-1.5
Intermitt. access day 15 inactive lever presses0.10.10.1-0.30.3-0.20.20.3-0.3-0.2-0.2-0.2-0.2-0.20.2-0.20.4-0.4
Intermitt. access escalation Index1.00.82.00.7-0.71.4-1.2-0.30.11.11.11.01.11.1-1.11.10.3-0.3
Intermittent access day 1 total infusions0.80.92.21.5-1.51.1-1.1-0.80.60.80.80.80.80.7-0.80.8-0.70.7
Intermittent access day 15 total infusions0.30.31.31.1-1.10.9-0.7-0.1-0.20.40.40.40.40.4-0.40.40.0-0.0
Intermittent access terminal intake (last 3 days)0.20.21.11.0-1.00.5-0.4-0.0-0.30.10.10.10.10.1-0.10.1-0.10.0
Intermittent access total infusions0.70.82.41.5-1.51.1-1.0-0.60.30.70.70.70.70.7-0.70.7-0.50.4
Intermittent access day 1 locomotion0.00.00.10.4-0.4-0.00.00.1-0.2-0.1-0.2-0.2-0.1-0.30.1-0.1-0.00.0
Intermittent access day 15 total locomotion0.50.61.71.3-1.30.7-0.7-0.80.60.50.50.50.50.4-0.50.5-0.80.8
Intermittent access total locomotion0.20.20.90.9-0.90.5-0.5-0.30.10.30.30.30.30.2-0.30.3-0.30.3
Intermittent access standard deviation0.30.31.30.2-0.2-0.10.30.7-1.1-0.5-0.5-0.4-0.5-0.50.5-0.50.6-0.7
Left kidney weight0.10.40.80.9-0.90.5-0.6-0.80.60.50.40.50.50.3-0.40.4-0.90.9
Right kidney weight0.10.40.90.8-0.80.4-0.4-0.80.70.40.40.50.40.5-0.30.3-1.01.0
Cocaine induced anxiety0.10.10.3-0.10.1-0.30.30.4-0.6-0.4-0.4-0.3-0.4-0.20.4-0.40.3-0.3
Post-drug Anxiety0.10.10.20.1-0.1-0.50.30.00.0-0.3-0.3-0.4-0.3-0.30.3-0.3-0.30.3
Baseline Anxiety0.20.20.70.4-0.40.2-0.3-0.70.80.40.40.20.40.3-0.40.4-0.70.7
Tail length11.033.444.74.9-4.96.7-6.5-5.45.36.46.56.56.46.3-6.36.3-3.33.2
Length with tail11.341.551.65.9-5.97.2-7.1-6.36.27.06.97.06.96.8-6.96.9-4.34.3
Length without tail1.32.84.52.1-2.11.6-1.7-1.81.71.51.51.41.51.4-1.61.6-1.71.7
Times rat made contact with spout0.10.10.2-0.20.20.5-0.40.1-0.00.40.40.40.40.4-0.40.40.5-0.5
Lifetime Intake0.30.31.01.0-1.00.9-0.7-0.2-0.10.50.50.50.50.5-0.50.50.0-0.0
Liver weight, left1.52.43.21.5-1.51.4-1.5-1.71.81.51.51.61.51.6-1.61.6-1.51.5
Liver weight, right1.22.02.51.2-1.21.4-1.4-1.51.61.51.51.51.51.4-1.51.5-1.21.2
Locomotor activity0.10.20.50.7-0.70.4-0.5-0.40.30.40.40.30.40.4-0.30.3-0.40.4
Locomotor testing distance0.10.20.40.5-0.5-0.50.3-0.20.1-0.3-0.3-0.4-0.3-0.30.5-0.5-0.60.6
Locomotor testing rearing0.20.30.50.7-0.70.7-0.7-0.50.40.70.70.60.70.6-0.40.4-0.40.4
Locomotion in novel chamber1.51.82.3-1.01.0-1.41.41.4-1.5-1.5-1.5-1.5-1.5-1.51.5-1.50.9-0.9
Locomotion in novel chamber post-restriction1.11.42.1-1.51.5-1.01.11.3-1.2-1.0-1.0-1.1-1.0-1.21.1-1.11.2-1.2
Fecal boli incidents, locomotor time 12.12.34.31.3-1.30.9-1.1-1.92.11.31.31.41.31.4-1.31.3-2.12.1
Change in fecal boli incidents, locomotor task0.20.10.4-0.00.0-0.20.20.5-0.6-0.4-0.4-0.4-0.5-0.30.4-0.40.4-0.4
Time >=10cm from walls, locomotor time 10.50.52.2-0.10.1-0.90.7-0.71.0-0.3-0.3-0.3-0.1-0.40.3-0.3-1.51.5
Bouts of movement, locomotor time 10.10.10.50.3-0.3-0.10.0-0.40.50.00.00.10.10.2-0.00.0-0.70.7
Total resting periods, locomotor time 10.30.30.8-0.40.4-0.90.80.2-0.2-0.7-0.7-0.7-0.7-0.60.7-0.7-0.30.3
Rest time, locomotor task time 10.20.20.4-0.30.3-0.30.40.5-0.6-0.5-0.5-0.5-0.4-0.30.5-0.50.5-0.5
Distance moved, locomotor task time 10.10.20.60.4-0.40.0-0.1-0.50.60.20.20.20.20.1-0.20.2-0.80.8
Vertical activity count, locomotor time 10.20.20.7-0.80.8-0.00.10.5-0.4-0.0-0.0-0.1-0.1-0.10.0-0.00.8-0.8
Time >=10cm from walls, locomotor time 21.01.14.81.3-1.3-0.30.0-1.31.30.10.10.10.30.0-0.10.1-2.22.2
Bouts of movement, locomotor time 21.01.12.2-0.40.4-1.51.30.6-0.6-1.3-1.3-1.3-1.2-1.31.3-1.3-0.30.3
Total resting periods, locomotor time 21.11.22.4-0.40.4-1.51.40.6-0.6-1.3-1.3-1.4-1.2-1.31.3-1.3-0.30.3
Rest time, locomotor task time 20.10.20.6-0.60.60.00.10.5-0.5-0.1-0.1-0.10.0-0.00.1-0.10.8-0.8
Distance moved, locomotor task time 20.20.21.10.5-0.5-0.30.1-0.60.70.00.00.00.1-0.1-0.00.0-1.11.1
Vertical activity count, locomotor time 20.30.30.5-0.40.4-0.70.70.5-0.5-0.7-0.7-0.7-0.6-0.70.7-0.70.2-0.2
Light reinforcement 12.03.76.4-0.80.8-1.61.82.1-2.5-2.2-2.2-2.1-2.2-2.12.0-2.01.6-1.6
Light reinforcement 20.50.61.31.2-1.2-0.60.5-0.1-0.2-0.8-0.8-0.7-0.8-0.80.7-0.7-0.90.9
Bone: marrow area4.59.711.73.3-3.32.9-3.0-3.43.43.03.03.13.03.1-3.03.0-3.03.0
Bone: maximum diameter0.81.62.01.3-1.31.1-1.1-1.41.41.21.21.21.21.3-1.21.2-1.31.3
Bone: maximum force3.05.26.62.4-2.42.6-2.6-2.22.02.42.42.42.42.4-2.42.4-1.51.5
Bone: maximum moment2.34.05.32.2-2.22.3-2.3-1.91.72.12.12.12.12.1-2.12.1-1.31.2
Mean time between licks in bursts0.30.51.9-1.01.00.10.10.9-0.8-0.1-0.1-0.1-0.1-0.20.1-0.11.4-1.4
Mean num. licks in bursts0.40.50.90.2-0.20.9-0.8-0.40.40.90.90.90.90.9-0.90.90.1-0.1
Cd content in liver0.70.71.70.2-0.21.3-1.1-0.30.31.01.01.01.01.1-1.01.00.5-0.5
Co content in liver0.60.71.6-1.11.1-0.50.61.1-1.1-0.6-0.6-0.6-0.6-0.50.6-0.61.3-1.3
Cu content in liver0.10.10.50.6-0.6-0.0-0.1-0.40.40.00.00.00.00.1-0.00.0-0.70.7
Fe content in liver1.92.24.02.0-2.01.4-1.5-1.61.51.31.31.31.31.3-1.31.3-1.61.6
K content in liver0.00.00.00.1-0.1-0.10.1-0.00.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.20.2
Mg content in liver0.20.20.50.7-0.70.3-0.3-0.50.50.30.30.30.30.3-0.30.3-0.60.6
Mn content in liver1.82.02.3-1.41.4-1.41.41.5-1.4-1.5-1.5-1.5-1.5-1.41.5-1.51.3-1.3
Na content in liver0.90.92.41.2-1.20.4-0.6-1.21.20.60.60.60.60.5-0.60.6-1.51.5
Rb content in liver0.81.03.31.2-1.20.2-0.4-1.31.30.50.50.50.50.5-0.50.5-1.81.8
Se content in liver0.20.20.90.9-0.9-0.10.0-0.1-0.2-0.4-0.4-0.4-0.4-0.40.4-0.4-0.40.4
Sr content in liver0.50.51.5-0.00.01.0-0.70.5-0.70.60.60.60.60.6-0.60.61.2-1.2
Zn content in liver0.00.00.1-0.20.20.2-0.20.10.00.20.20.20.20.1-0.20.20.3-0.3
Bone: minimum diameter0.81.62.71.6-1.61.2-1.2-1.31.21.11.11.11.11.2-1.11.1-1.31.3
Time in familiar zone, hab. session 10.30.20.5-0.70.70.4-0.30.2-0.00.40.40.40.40.5-0.50.50.7-0.7
Time in novel zone, hab. session 10.20.20.40.5-0.5-0.40.3-0.1-0.0-0.4-0.4-0.4-0.4-0.50.5-0.5-0.60.6
Total zone transitions, hab. session 10.10.10.4-0.50.5-0.60.5-0.00.2-0.3-0.3-0.3-0.2-0.30.4-0.4-0.30.3
Total locomotion distance, hab. session 10.20.41.50.8-0.8-0.30.2-0.60.5-0.1-0.1-0.1-0.1-0.00.3-0.3-1.21.2
Locomotion velocity, hab. session 10.30.51.21.1-1.10.3-0.4-0.80.70.40.40.40.40.5-0.20.2-1.11.1
Time in familiar zone, hab. session 21.41.41.9-1.11.1-1.31.31.2-1.2-1.2-1.2-1.2-1.2-1.31.4-1.40.8-0.8
Time in novel zone, hab. session 20.60.61.11.0-1.00.9-0.9-0.70.50.80.80.80.80.9-0.60.6-0.50.5
Total zone transitions, hab. session 20.20.30.7-0.30.30.7-0.5-0.10.00.60.60.70.60.8-0.50.50.4-0.4
Total locomotion distance, hab. session 20.50.71.40.6-0.61.1-1.0-0.50.41.01.01.01.01.2-0.80.8-0.10.1
Locomotion velocity, hab. session 20.81.12.20.6-0.61.4-1.2-0.70.61.31.31.31.31.5-1.11.1-0.10.1
Novel to familiar place preference ratio2.02.15.12.3-2.31.3-1.4-1.51.21.21.21.21.21.1-1.11.1-1.61.5
Novelty place preference2.12.24.92.2-2.21.4-1.5-1.51.31.21.21.21.21.2-1.11.1-1.51.5
Time in novel zone, NPP test1.71.74.42.1-2.11.2-1.3-1.41.11.01.01.01.00.9-0.90.9-1.41.4
Total zone transitions, NPP test0.10.20.2-0.40.4-0.40.40.5-0.5-0.4-0.4-0.4-0.4-0.20.4-0.40.4-0.4
Total locomotion distance, NPP test0.20.30.70.2-0.2-0.60.60.4-0.6-0.7-0.7-0.7-0.7-0.50.8-0.8-0.10.1
Locomotion velocity, NPP test0.20.30.50.1-0.1-0.50.50.4-0.6-0.6-0.6-0.6-0.6-0.40.7-0.70.1-0.1
Intraocular pressure3.24.55.2-2.12.1-2.12.22.3-2.3-2.2-2.2-2.2-2.2-2.02.2-2.21.8-1.8
Delta distance traveled before/after self-admin1.82.03.3-0.90.9-1.31.41.6-1.8-1.5-1.5-1.5-1.5-1.41.5-1.51.3-1.3
Delta ambulatory time before/after self-admin1.31.42.7-0.20.2-1.01.11.3-1.7-1.4-1.4-1.4-1.4-1.21.3-1.31.0-1.0
Parametrial fat weight0.00.00.00.1-0.10.1-0.10.0-0.10.00.00.00.0-0.00.0-0.00.0-0.0
Pavlov. Cond. lever latency0.60.72.6-1.41.40.20.10.9-0.70.10.10.10.10.2-0.10.11.6-1.6
Pavlov. Cond. magazine entry latency0.50.62.41.2-1.2-0.40.2-0.80.7-0.3-0.3-0.3-0.3-0.40.2-0.2-1.51.5
Pavlov. Cond. change in total contacts0.80.92.20.8-0.8-1.10.8-0.40.3-0.9-0.9-0.9-0.9-0.90.8-0.8-1.51.5
Pavlov. Cond. index score0.50.72.31.5-1.5-0.2-0.0-0.80.6-0.2-0.2-0.2-0.2-0.30.1-0.1-1.51.5
Pavlov. Cond. latency score0.81.03.31.7-1.7-0.1-0.2-1.10.90.00.00.00.0-0.1-0.00.0-1.81.8
Pavlov. Cond. lever contacts0.50.62.11.4-1.4-0.2-0.0-0.80.6-0.2-0.2-0.2-0.2-0.30.1-0.1-1.51.5
Pavlov. Cond. magazine entry number0.50.62.2-1.11.10.20.00.9-0.80.00.00.00.00.10.0-0.01.5-1.5
Pavlov. Cond. intertrial magazine entries1.01.21.71.2-1.21.3-1.3-1.01.01.21.21.21.21.1-1.21.2-0.60.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.91.2-1.2-0.40.2-0.60.5-0.4-0.4-0.4-0.4-0.50.3-0.3-1.41.4
Pavlov. Cond. response bias0.30.41.41.1-1.1-0.1-0.1-0.70.5-0.1-0.1-0.1-0.1-0.20.0-0.0-1.21.2
Pavlov. Cond. lever latency0.60.82.00.6-0.61.4-1.3-0.30.21.01.01.01.01.0-1.11.10.4-0.5
Pavlov. Cond. magazine entry latency0.20.21.1-1.01.0-0.40.40.3-0.1-0.1-0.1-0.1-0.1-0.20.2-0.20.5-0.4
Pavlov. Cond. change in total contacts0.50.71.8-0.10.1-1.31.1-0.10.2-0.9-0.9-0.9-0.9-0.90.9-0.9-1.11.1
Pavlov. Cond. index score0.40.51.3-0.50.5-1.11.00.2-0.0-0.8-0.8-0.8-0.8-0.80.8-0.8-0.50.5
Pavlov. Cond. latency score0.30.40.9-0.40.4-1.00.80.1-0.0-0.6-0.6-0.6-0.6-0.60.7-0.7-0.40.4
Pavlov. Cond. lever contacts0.60.81.8-0.10.1-1.31.1-0.10.1-0.9-0.9-0.9-0.9-0.91.0-1.0-1.01.1
Pavlov. Cond. magazine entry number0.10.10.3-0.20.2-0.10.10.5-0.6-0.3-0.3-0.3-0.3-0.30.2-0.20.6-0.6
Pavlov. Cond. intertrial magazine entries0.10.20.30.5-0.5-0.30.20.1-0.4-0.4-0.4-0.4-0.4-0.50.4-0.4-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.50.5-1.21.00.2-0.1-0.8-0.8-0.8-0.8-0.80.8-0.8-0.50.5
Pavlov. Cond. response bias0.20.31.20.0-0.0-0.70.5-0.50.6-0.2-0.2-0.2-0.2-0.30.3-0.3-1.11.1
Time in closed arm before self-admin5.15.77.42.7-2.72.1-2.3-2.72.72.22.22.22.22.2-2.32.3-2.42.4
Time in closed arm after self-admin0.70.81.70.9-0.90.3-0.5-1.11.30.60.60.60.60.6-0.70.7-1.31.3
Time in open arm before self-admin5.35.810.0-2.42.4-1.62.03.0-3.2-2.1-2.1-2.1-2.1-2.22.2-2.23.0-3.0
Time in open arm after self-admin0.40.40.60.8-0.80.7-0.7-0.70.70.60.60.60.60.5-0.60.6-0.60.6
Bone: periosteal estimation3.06.17.22.7-2.72.3-2.4-2.72.62.42.42.42.42.5-2.42.4-2.42.4
Bone: periosteal perimeter2.23.64.62.1-2.11.8-1.8-2.12.01.81.81.81.81.9-1.81.8-1.91.9
Bone: post-yield work1.41.92.91.5-1.51.7-1.6-1.21.11.51.51.51.51.5-1.51.5-0.70.7
Progressive ratio test 1 active lever presses0.20.20.60.2-0.20.8-0.60.0-0.10.60.50.60.60.4-0.60.60.5-0.5
Progressive ratio test 1 breakpoint0.20.20.60.3-0.30.8-0.6-0.1-0.00.50.50.60.50.5-0.50.50.3-0.3
Progressive ratio test 1 inactive lever presses1.51.76.9-1.31.30.40.21.8-2.1-0.1-0.1-0.2-0.1-0.20.1-0.12.6-2.6
Progressive ratio test 2 active lever presses0.50.61.40.2-0.21.2-0.9-0.20.10.90.91.00.90.9-0.90.90.4-0.4
Progressive ratio test 2 breakpoint0.10.10.30.0-0.00.6-0.30.2-0.40.30.30.40.30.3-0.30.30.6-0.6
Progressive ratio test 2 inactive lever presses0.10.20.7-0.20.20.3-0.00.6-0.70.0-0.0-0.10.0-0.1-0.00.00.8-0.8
Incentive Sensitization - Responses0.80.81.50.5-0.51.2-1.1-0.60.61.01.11.21.01.1-1.01.0-0.10.1
Incentive Sensitization - Breakpoint0.70.71.30.4-0.41.2-1.0-0.50.51.01.01.11.01.0-1.01.0-0.00.0
Sum of active levers in priming session hrs 5-61.11.01.71.3-1.30.9-1.0-1.21.10.80.80.80.80.8-0.80.8-1.31.3
Progressive ratio0.70.82.1-1.51.5-0.50.61.0-0.9-0.4-0.4-0.5-0.4-0.90.5-0.51.3-1.3
Food seeking constrained by brief footshock0.10.10.3-0.20.20.4-0.3-0.00.10.30.30.40.30.5-0.40.40.3-0.3
Seeking ratio, punishment vs. effort1.01.22.31.3-1.31.1-1.1-1.21.10.90.91.10.91.5-1.01.0-1.01.0
Retroperitoneal fat weight0.10.21.01.0-1.00.7-0.6-0.0-0.40.20.20.20.20.1-0.20.20.1-0.1
Reaction time number correct0.50.81.2-0.50.5-1.01.00.7-0.8-1.1-1.1-1.1-1.1-0.91.0-1.00.2-0.2
Reaction time mean minus median0.91.12.51.3-1.31.6-1.4-0.70.41.11.11.11.11.2-1.11.1-0.10.1
Reaction time mean minus median AUC0.40.51.10.9-0.91.0-0.9-0.50.30.70.70.80.70.8-0.70.7-0.20.2
Reaction time num false alarms3.14.25.4-2.32.3-1.82.02.3-2.2-2.0-2.0-2.0-2.0-1.81.8-1.82.1-2.1
Reaction time num false alarms AUC3.54.86.7-2.62.6-1.92.02.5-2.4-2.1-2.1-2.0-2.1-1.91.8-1.82.4-2.4
Reaction time trials correct on left0.50.81.2-0.50.5-1.01.00.7-0.8-1.1-1.1-1.1-1.1-0.91.0-1.00.2-0.2
Reaction time trials on left0.40.61.0-0.50.5-1.00.90.7-0.7-1.0-1.0-1.0-1.0-0.90.9-0.90.2-0.2
Reaction time mean2.23.05.01.6-1.62.2-2.1-1.41.41.91.92.01.91.9-2.02.0-0.70.7
Reaction time mean AUC1.72.34.31.4-1.42.1-1.9-1.11.01.71.71.71.71.7-1.81.8-0.40.4
Median of all reaction times2.02.74.11.4-1.42.0-1.9-1.41.41.81.81.91.81.8-1.91.9-0.70.7
Reaction time omissions0.60.81.51.2-1.21.2-1.1-0.70.50.90.90.80.90.9-0.80.8-0.30.3
Reaction time false alarm rate1.52.23.7-1.91.9-1.11.21.7-1.6-1.3-1.3-1.2-1.3-1.11.1-1.11.9-1.8
Reaction time premature initiation rate3.04.07.5-0.50.5-2.72.41.1-1.2-2.5-2.5-2.5-2.5-2.52.5-2.5-0.40.4
Reaction time premature initiations3.85.39.5-0.80.8-3.12.81.5-1.6-2.8-2.8-2.9-2.8-2.82.8-2.8-0.10.1
Std. dev. reaction times1.82.53.91.8-1.82.0-1.9-1.41.21.71.71.71.71.7-1.71.7-0.90.8
Reaction time trials completed0.40.61.0-0.50.5-1.00.90.7-0.7-1.0-1.0-1.0-1.0-0.90.9-0.90.2-0.2
Reaction time trials AUC0.50.71.0-0.50.5-0.90.90.7-0.8-1.0-1.0-1.0-1.0-0.90.9-0.90.3-0.3
Run reversals in cocaine runway, females0.30.30.8-0.90.90.4-0.10.3-0.10.30.30.60.30.4-0.30.30.7-0.7
Run reversals in cocaine runway, males0.60.61.00.2-0.2-1.00.80.1-0.2-1.0-1.0-0.9-1.0-0.91.0-1.0-0.60.6
Latency to leave start box in cocaine runway6.16.68.1-2.72.7-2.52.62.8-2.8-2.6-2.6-2.4-2.6-2.42.5-2.52.4-2.4
Latency to leave start box in cocaine runway, F4.95.47.4-2.72.7-2.12.32.6-2.6-2.1-2.1-2.0-2.1-2.12.1-2.12.4-2.4
Latency to leave start box in cocaine runway, M1.21.11.5-1.01.0-1.21.21.0-0.9-1.2-1.2-1.0-1.2-1.11.2-1.20.6-0.6
Std. dev. time between licks in bursts3.13.75.4-1.41.4-1.71.82.2-2.3-2.1-2.1-2.1-2.1-2.02.1-2.11.8-1.8
Total sessions with >9 infusions0.60.71.9-0.90.9-0.20.51.2-1.3-0.5-0.6-0.5-0.5-0.50.5-0.51.4-1.4
Short access day 1 total inactive lever presses0.40.51.00.9-0.9-0.60.40.1-0.4-0.7-0.7-0.9-0.7-1.00.7-0.7-0.40.4
Short access day 10 total inactive lever presses0.00.10.1-0.20.2-0.10.20.3-0.3-0.2-0.1-0.3-0.2-0.30.2-0.20.3-0.3
Short access day 1 total infusions0.10.10.50.3-0.30.10.00.4-0.7-0.2-0.2-0.2-0.2-0.00.2-0.20.5-0.5
Short access day 10 total infusions0.50.52.41.6-1.60.6-0.6-0.60.30.30.30.30.30.3-0.30.3-0.70.7
Short access total infusions0.10.10.40.4-0.40.00.10.4-0.6-0.3-0.3-0.3-0.3-0.20.3-0.30.3-0.4
Short access day 1 locomotion0.20.20.8-0.40.40.20.00.6-0.60.0-0.10.00.0-0.1-0.00.00.9-0.9
Short access day 10 total locomotion0.30.30.50.6-0.6-0.60.4-0.0-0.1-0.6-0.7-0.7-0.6-0.70.6-0.6-0.60.6
Short access total locomotion0.20.20.50.4-0.40.7-0.6-0.20.10.50.50.50.50.5-0.50.50.1-0.1
One hour access (0.3 mA shock)0.30.31.81.3-1.30.3-0.4-0.30.00.0-0.00.10.00.0-0.00.0-0.60.5
Compulsive drug intake0.10.10.2-0.50.5-0.30.30.3-0.2-0.2-0.2-0.2-0.2-0.30.2-0.20.3-0.3
One hour access (shock baseline)0.80.93.51.9-1.90.9-0.9-0.80.50.50.50.60.50.5-0.50.5-0.90.9
Social response proportion4.14.47.22.7-2.71.9-2.1-2.32.01.91.91.91.92.0-1.91.9-2.12.1
Social responses1.41.84.32.1-2.11.6-1.6-1.10.61.31.31.21.31.4-1.21.2-0.70.7
Social time0.50.61.31.1-1.11.1-1.0-0.50.20.80.80.70.80.8-0.70.7-0.20.2
Soleus weight0.10.30.80.9-0.90.2-0.4-0.70.70.30.30.30.30.3-0.40.4-0.90.9
Bone: stiffness3.96.19.02.2-2.23.0-2.9-2.22.12.82.82.72.82.8-2.82.8-1.11.1
Tibialis anterior weight0.51.72.9-1.71.7-1.01.11.5-1.4-1.1-1.1-1.0-1.1-1.01.1-1.11.6-1.6
Time to tail flick, vehicle, before self-admin0.30.31.5-1.21.20.10.10.4-0.20.10.10.10.10.1-0.10.10.7-0.7
Time to tail flick, vehicle, after self-admin0.20.20.4-0.40.40.4-0.4-0.30.50.60.60.60.60.6-0.50.5-0.00.0
Time to tail flick, test, before self-admin0.70.71.1-0.70.7-1.01.00.7-0.7-1.0-1.0-1.0-1.0-1.01.0-1.00.3-0.3
Time to tail flick, test, after self-admin0.70.72.1-1.01.0-0.20.41.1-1.1-0.4-0.4-0.4-0.4-0.40.5-0.51.5-1.5
Delta time to tail flick, vehicle, before/after SA0.00.00.10.4-0.40.1-0.2-0.1-0.00.10.10.10.1-0.0-0.00.0-0.10.1
Delta time to tail flick, test, before/after SA0.20.20.8-0.50.5-0.00.10.6-0.6-0.1-0.1-0.1-0.1-0.10.2-0.20.9-0.9
Tibia length6.017.121.63.2-3.24.6-4.6-3.94.14.64.64.74.64.6-4.64.6-2.42.4
Ambulatory time before self-admin0.90.91.41.2-1.20.7-0.9-1.11.20.90.90.80.90.7-0.80.8-1.11.1
Ambulatory time after self-admin1.61.83.0-0.10.1-1.41.41.2-1.4-1.7-1.7-1.7-1.7-1.71.6-1.60.5-0.5
Bone: tissue strength1.41.43.00.4-0.41.7-1.6-0.50.51.41.41.41.41.4-1.41.40.5-0.6
Total heroin consumption0.00.00.10.2-0.20.3-0.3-0.20.20.20.20.20.20.2-0.20.2-0.20.2
Bone: trabecular number4.26.58.62.2-2.22.4-2.5-2.82.92.72.72.72.72.7-2.72.7-2.32.3
Bone: trabecular spacing0.50.71.2-1.11.1-0.90.90.8-0.7-0.7-0.7-0.8-0.7-0.90.7-0.70.7-0.7
Bone: trabecular thickness1.82.13.31.6-1.61.1-1.2-1.81.81.31.31.31.31.3-1.31.3-1.81.8
Bone: trabecular tissue density0.20.31.1-0.50.50.10.00.7-0.7-0.2-0.2-0.2-0.2-0.20.2-0.21.0-1.0
Water consumed over 24 hours0.70.81.1-0.70.7-1.11.00.8-0.8-1.0-1.0-1.0-1.0-1.01.0-1.00.5-0.5
Number of responses in last shaping day0.91.03.6-1.51.50.20.21.2-1.2-0.0-0.0-0.0-0.0-0.10.0-0.01.9-1.9