Colgalt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Colgalt1 0.07 0.05 4.5e-05 0.02 0.05 0.04 0.04 9.4e-03 3.4e-05 2.2e-04 1.5e-04
2 Liver intron excision ratio chr16_18354025_18354854 0.06 0.04 5.8e-05 0.03 0.03 0.02 0.03 4.7e-04 2.0e-04 1.0e-03 3.5e-04
3 NAcc mRNA stability Colgalt1 0.11 0.07 3.4e-11 0.08 0.07 0.07 0.07 1.4e-11 2.2e-11 5.6e-11 4.5e-11
4 Liver intron excision ratio chr16_18354964_18355594 0.06 0.04 3.4e-04 0.03 0.03 0.02 0.03 1.3e-04 8.2e-04 2.0e-03 5.5e-04
5 Liver mRNA stability Colgalt1 0.08 0.05 5.2e-08 0.08 0.06 0.07 0.07 5.8e-09 1.3e-07 7.0e-08 3.0e-08
6 pVTA mRNA stability Colgalt1 0.18 0.09 5.1e-10 0.14 0.13 0.13 0.14 1.4e-11 1.4e-10 2.7e-10 4.1e-11
7 PL mRNA stability Colgalt1 0.07 0.04 9.4e-07 0.04 0.06 0.06 0.03 5.9e-05 1.1e-06 8.2e-07 3.9e-04
8 NAcc intron excision ratio chr16_18354025_18354854 0.03 0.03 2.8e-04 0.01 0.02 0.01 0.02 2.6e-03 6.9e-04 3.9e-03 1.0e-03
9 NAcc intron excision ratio chr16_18354964_18355594 0.03 0.02 6.8e-04 0.01 0.01 0.01 0.01 5.9e-03 1.9e-03 9.9e-03 3.0e-03
10 Brain mRNA stability Colgalt1 0.03 0.03 8.3e-03 0.02 0.01 0.02 0.01 1.1e-02 7.6e-02 1.2e-02 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.83.14.6-2.0-2.11.71.71.81.71.6-1.91.90.0
Area under the delay curve0.91.11.40.81.0-1.2-1.1-1.1-0.9-1.21.2-1.20.0
BMI with tail2.17.29.6-3.1-3.03.03.03.13.12.5-2.32.20.0
BMI without tail1.95.711.6-3.4-2.92.62.52.82.91.6-1.61.50.0
Body weight5.423.736.9-6.1-5.85.35.35.55.24.1-4.24.10.0
Weight adjusted by age1.21.83.9-2.0-1.71.41.31.31.51.1-1.01.00.0
Bone surface1.73.04.2-1.5-1.91.71.71.81.81.9-2.12.00.0
Bone volume2.13.85.2-2.1-2.32.02.02.02.11.9-2.02.00.0
Breakpoint value in progressive ratio session0.81.02.3-0.4-0.90.90.80.81.01.1-1.51.50.0
Number of licking bursts0.10.20.20.50.5-0.5-0.5-0.3-0.3-0.40.4-0.40.0
Context. condit. distance diff. score0.10.10.1-0.3-0.30.30.30.30.00.1-0.20.20.0
Locomotion velocity, session 13.74.06.9-0.6-1.62.02.12.12.02.6-2.52.50.0
Locomotion distance, session 11.31.74.20.4-0.61.21.21.11.22.1-1.71.80.0
Locomotion velocity, session 22.12.43.2-1.7-1.81.71.71.71.81.4-1.41.40.0
Locomotion distance, session 20.71.03.20.7-0.30.90.90.60.91.8-1.31.40.0
Locomotion velocity, session 30.00.10.20.1-0.10.00.10.10.30.4-0.40.40.0
Locomotion distance, session 30.30.40.90.1-0.30.40.50.60.60.9-0.80.90.0
Stereotopy head waving bouts, day 30.10.10.20.0-0.2-0.1-0.10.20.10.3-0.50.50.0
Stereotopy head waving duration, day 30.10.10.2-0.3-0.30.10.10.20.30.2-0.40.40.0
Locomotion velocity, session 70.50.51.81.31.1-0.7-0.5-0.6-0.5-0.30.6-0.60.0
Locomotion distance, session 71.41.83.41.91.7-1.4-1.3-1.4-1.4-1.01.3-1.20.0
Stereotopy head waving bouts, day 72.42.73.6-1.4-1.81.61.61.81.81.8-1.91.90.0
Stereotopy head waving duration, day 72.22.63.7-1.8-1.91.61.61.81.71.5-1.81.70.0
Locomotion velocity, session 81.11.32.70.1-0.71.31.31.11.11.6-1.41.40.0
Locomotion distance, session 81.21.73.6-0.1-0.91.51.51.31.21.9-1.51.60.0
Degree of sensitization distance1.92.02.71.31.6-1.4-1.4-1.4-1.6-1.51.6-1.60.0
Degree of sensitization stereotypy2.93.23.9-1.6-1.91.81.92.02.01.9-1.91.90.0
Conditioned locomotion0.10.20.30.40.4-0.5-0.5-0.4-0.4-0.40.3-0.30.0
Cocaine response after cond. corrected3.23.96.40.71.6-2.3-2.3-2.2-2.2-2.52.2-2.20.0
Cocaine response after cond. not corrected2.63.04.41.01.6-2.0-2.0-2.0-2.0-2.11.8-1.80.0
Cocaine response before conditioning0.60.81.80.4-0.31.01.00.70.91.3-1.11.10.0
Saline control response1.11.42.5-0.6-1.11.31.31.31.31.6-1.41.40.0
Bone: connectivity density1.11.72.6-1.3-1.51.31.31.31.21.3-1.61.60.0
Bone: cortical apparent density0.00.00.10.20.2-0.1-0.2-0.3-0.2-0.10.1-0.10.0
Bone: cortical area6.29.515.2-3.9-3.63.53.63.63.52.5-2.42.30.0
Bone: cortical porosity1.01.12.2-0.0-0.61.31.31.11.21.5-1.21.20.0
Bone: cortical porosity1.21.42.6-0.2-0.81.41.41.21.31.6-1.31.30.0
Bone: cortical thickness6.410.614.9-3.8-3.73.73.73.93.62.9-2.82.70.0
Bone: cortical thickness3.03.65.4-2.3-2.22.12.12.32.11.6-1.51.50.0
Bone: cortical tissue density0.10.10.20.40.3-0.2-0.3-0.4-0.3-0.20.2-0.20.0
Condit. Reinf. active minus inactive responses2.32.63.4-1.3-1.71.71.71.81.91.7-1.71.70.0
Condit. Reinf. active-inactive response ratio0.40.40.6-0.7-0.70.70.60.70.80.5-0.60.50.0
Condit. Reinf. active responses3.03.74.7-1.6-2.02.12.12.12.22.0-2.02.00.0
Condit. Reinf. inactive responses0.60.81.1-0.8-0.91.11.11.01.00.9-0.80.80.0
Incentive salience index mean5.97.39.1-2.1-2.82.92.92.93.03.0-3.03.00.0
Condit. Reinf. lever presses9.112.816.5-2.6-3.63.93.93.93.94.1-4.04.00.0
Condit. Reinf. active minus inactive responses0.30.40.8-0.1-0.40.50.60.70.60.9-0.80.80.0
Condit. Reinf. active-inactive response ratio0.50.61.0-0.9-0.80.90.90.91.00.7-0.60.60.0
Condit. Reinf. active responses0.10.10.70.80.4-0.2-0.1-0.00.00.5-0.20.30.0
Condit. Reinf. inactive responses1.62.04.32.11.8-1.6-1.6-1.5-1.5-0.81.1-1.00.0
Condit. Reinf. lever presses0.00.00.0-0.1-0.1-0.1-0.10.10.1-0.10.0-0.00.0
Condit. Reinf. lever reinforcers received0.10.10.30.50.4-0.4-0.3-0.2-0.20.10.1-0.10.0
Conditioned reinforcement - actives0.10.21.1-1.1-0.50.30.30.30.2-0.20.3-0.30.0
Conditioned reinforcement - inactives1.11.67.5-2.7-1.81.21.31.11.20.0-0.20.10.0
Conditioned locomotion0.30.41.2-0.80.0-0.3-0.4-0.3-0.5-1.01.0-1.10.0
Patch foraging indifference point 0 sec1.22.35.4-2.3-2.11.61.51.51.40.8-1.41.30.0
Patch foraging indifference point AUC0.30.40.90.30.4-0.9-0.9-0.8-0.6-0.80.4-0.40.0
Delay disc. indifference point, 0s delay1.31.53.01.71.5-1.4-1.3-1.2-1.2-0.81.0-1.00.0
Delay disc. indifference point, 16s delay4.55.06.31.92.4-2.4-2.4-2.3-2.5-2.52.4-2.40.0
Delay disc. indifference point, 2s delay0.10.10.30.50.1-0.00.10.00.20.4-0.40.40.0
Delay disc. indifference point, 24s delay0.60.61.20.20.7-0.7-0.7-0.7-0.9-1.01.1-1.10.0
Delay disc. indifference point, 4s delay0.30.30.5-0.3-0.50.60.60.60.70.7-0.60.60.0
Delay disc. indifference point, 8s delay1.61.93.30.51.1-1.7-1.6-1.5-1.2-1.81.6-1.60.0
Indifference point function ln k0.30.51.1-0.6-0.51.11.01.00.70.6-0.10.10.0
Indifference point function log k0.30.51.1-0.6-0.51.11.01.00.70.6-0.10.10.0
Patch foraging total patch changes 0 sec1.52.87.5-2.7-2.31.81.71.71.60.8-1.31.20.0
Patch foraging total patch changes 12 sec0.20.21.2-1.1-0.70.00.00.00.4-0.3-0.10.10.0
Patch foraging total patch changes 18 sec0.20.30.70.30.3-0.8-0.8-0.6-0.7-0.70.2-0.20.0
Patch foraging total patch changes 24 sec0.20.30.7-0.8-0.80.30.30.40.40.3-0.70.70.0
Patch foraging total patch changes 6 sec0.81.23.4-1.9-1.61.01.01.00.90.4-1.00.90.0
Patch foraging time to switch 0 sec0.10.21.11.10.7-0.5-0.4-0.3-0.50.10.00.00.0
Patch foraging water rate 0 sec0.91.93.1-1.7-1.61.81.51.41.71.2-1.00.90.0
Patch foraging water rate 12 sec0.30.61.2-0.8-0.71.11.01.00.90.9-0.30.30.0
Patch foraging water rate 18 sec0.50.71.80.0-0.51.11.00.80.91.3-1.01.00.0
Patch foraging water rate 24 sec2.53.66.1-1.2-1.72.52.42.02.22.3-1.71.60.0
Patch foraging water rate 6 sec0.30.41.0-1.0-0.60.90.70.61.00.40.1-0.10.0
Seeking ratio, delayed vs. immediate footshock0.10.20.40.60.40.40.40.2-0.10.50.4-0.40.0
Distance traveled before self-admin0.91.21.8-1.4-1.31.21.21.01.40.9-1.11.00.0
Distance traveled after self-admin2.32.83.8-1.8-1.91.81.71.61.81.7-1.81.70.0
Extensor digitorum longus weight0.72.73.9-2.0-1.91.71.71.91.81.5-1.41.40.0
Bone: elastic displacement0.80.91.9-0.2-0.71.11.11.01.11.4-1.01.10.0
Bone: elastic work2.02.64.1-2.0-1.81.91.91.82.01.3-1.11.10.0
Bone: endosteal estimation0.51.01.80.50.9-0.9-0.9-1.2-0.9-1.31.3-1.30.0
Bone: endosteal perimeter0.10.20.6-0.8-0.30.40.40.20.4-0.30.3-0.40.0
Epididymis fat weight0.93.14.3-1.9-2.02.12.12.02.01.5-1.51.40.0
Delta time in closed arm before/after self-admin0.90.81.80.40.7-0.9-1.1-1.0-0.9-1.31.0-1.00.0
Delta time in open arm before/after self-admin0.10.10.40.70.4-0.2-0.1-0.3-0.30.1-0.10.10.0
Diff in mean of infusions in LGA sessions0.40.51.2-1.1-0.90.70.70.50.80.2-0.50.50.0
Delay discount exponential model param0.50.50.9-0.4-0.60.80.80.80.71.0-0.90.90.0
Extinction: sum of active levers before priming0.91.02.20.0-0.71.00.90.80.81.3-1.41.50.0
Active lever presses in extinction session 60.00.00.10.30.20.1-0.2-0.20.10.00.1-0.10.0
Bone: final force3.96.214.5-3.8-3.12.72.72.73.01.4-1.51.40.0
Bone: final moment2.94.612.1-3.5-2.72.32.42.42.61.0-1.11.00.0
Food consumed during 24 hour testing period0.91.22.7-0.1-0.80.90.91.21.21.6-1.41.50.0
Glucose0.81.32.3-1.5-1.31.31.31.31.30.6-0.90.80.0
Heart weight3.25.06.4-2.4-2.52.42.52.52.32.2-2.22.10.0
Delay discount hyperbolic model param0.20.20.3-0.2-0.30.50.50.50.30.6-0.50.50.0
Intermittent access intake day 1-15 change0.20.50.6-0.6-0.80.80.80.80.60.8-0.80.80.0
Intermittent access intake escalation0.20.40.6-0.4-0.60.70.70.70.60.8-0.70.70.0
Intermittent access intake escalation 20.30.30.5-0.7-0.70.60.60.70.60.5-0.50.40.0
Intermitt. access day 1 inactive lever presses0.00.10.3-0.6-0.40.30.30.40.40.1-0.0-0.00.0
Intermitt. access day 15 inactive lever presses0.00.00.10.20.2-0.1-0.1-0.1-0.0-0.00.2-0.20.0
Intermitt. access escalation Index0.60.81.21.11.1-0.9-1.0-1.0-0.9-0.70.9-0.90.0
Intermittent access day 1 total infusions0.61.02.5-0.10.6-0.8-0.8-1.0-0.9-1.61.4-1.40.0
Intermittent access day 15 total infusions0.10.10.2-0.20.2-0.2-0.1-0.2-0.4-0.50.5-0.50.0
Intermittent access terminal intake (last 3 days)0.20.30.70.10.4-0.6-0.5-0.6-0.7-0.90.6-0.70.0
Intermittent access total infusions0.40.51.5-0.50.2-0.5-0.4-0.6-0.8-1.20.9-1.00.0
Intermittent access day 1 locomotion0.20.30.9-0.8-0.2-0.1-0.1-0.2-0.5-1.00.7-0.70.0
Intermittent access day 15 total locomotion0.00.10.2-0.10.0-0.2-0.2-0.2-0.4-0.40.0-0.00.0
Intermittent access total locomotion0.20.21.1-1.0-0.50.10.10.0-0.4-0.70.2-0.20.0
Intermittent access standard deviation0.00.10.2-0.30.1-0.1-0.1-0.1-0.2-0.30.4-0.50.0
Left kidney weight0.94.45.9-2.3-2.42.32.32.42.02.0-2.12.00.0
Right kidney weight1.67.39.9-3.1-3.13.03.03.12.82.3-2.52.40.0
Cocaine induced anxiety0.30.41.6-1.2-0.90.50.40.50.40.0-0.40.40.0
Post-drug Anxiety0.00.00.1-0.2-0.10.10.00.10.20.00.1-0.10.0
Baseline Anxiety0.50.62.61.61.2-0.6-0.6-0.6-0.40.10.6-0.60.0
Tail length0.83.15.6-2.4-2.22.01.92.11.91.3-1.41.30.0
Length with tail2.39.915.6-3.9-3.93.43.33.43.12.5-3.02.90.0
Length without tail2.16.810.1-3.2-3.22.92.92.72.32.3-2.62.60.0
Times rat made contact with spout0.00.00.20.40.2-0.2-0.2-0.00.00.2-0.10.10.0
Lifetime Intake0.30.31.0-1.0-0.2-0.00.0-0.2-0.4-0.90.7-0.80.0
Liver weight, left0.81.32.9-0.2-0.81.11.21.41.11.7-1.41.40.0
Liver weight, right1.12.03.1-1.8-1.71.61.61.81.41.2-1.11.10.0
Locomotor activity3.96.19.2-1.3-2.22.72.72.82.63.0-2.82.80.0
Locomotor testing distance0.91.63.2-0.3-1.01.31.31.61.31.8-1.51.50.0
Locomotor testing rearing1.01.94.2-0.2-1.11.31.31.41.21.8-2.02.00.0
Locomotion in novel chamber0.50.71.0-0.7-0.90.80.60.90.81.0-0.90.90.0
Locomotion in novel chamber post-restriction2.03.25.7-0.9-1.71.81.71.91.82.1-2.42.40.0
Fecal boli incidents, locomotor time 10.71.01.41.01.1-1.0-1.0-1.1-0.7-1.01.2-1.20.0
Change in fecal boli incidents, locomotor task0.40.40.60.70.7-0.8-0.7-0.8-0.7-0.60.5-0.50.0
Time >=10cm from walls, locomotor time 10.50.50.90.50.7-0.6-0.7-0.9-0.7-0.90.8-0.80.0
Bouts of movement, locomotor time 10.10.10.40.60.3-0.4-0.6-0.2-0.30.1-0.30.30.0
Total resting periods, locomotor time 10.30.31.01.00.7-0.6-0.8-0.6-0.7-0.1-0.00.10.0
Rest time, locomotor task time 10.70.81.30.60.9-1.0-1.2-0.9-0.7-0.81.1-1.10.0
Distance moved, locomotor task time 10.00.00.10.10.1-0.10.0-0.1-0.2-0.30.0-0.00.0
Vertical activity count, locomotor time 10.41.01.5-0.6-1.01.21.21.20.91.1-1.11.10.0
Time >=10cm from walls, locomotor time 20.81.22.41.31.4-0.8-0.9-1.0-0.9-0.91.5-1.50.0
Bouts of movement, locomotor time 20.40.61.5-0.4-0.70.60.50.70.21.0-1.21.20.0
Total resting periods, locomotor time 20.20.41.3-0.4-0.70.40.30.50.00.8-1.11.10.0
Rest time, locomotor task time 20.10.20.5-0.7-0.60.40.30.40.20.2-0.40.40.0
Distance moved, locomotor task time 20.80.91.60.81.1-0.9-0.9-0.9-0.9-0.91.3-1.30.0
Vertical activity count, locomotor time 20.10.10.6-0.3-0.30.50.40.40.80.40.0-0.00.0
Light reinforcement 10.30.71.10.50.8-0.9-0.9-0.9-0.7-1.10.8-0.90.0
Light reinforcement 22.74.17.90.81.6-2.4-2.2-2.1-2.3-2.82.2-2.20.0
Bone: marrow area0.41.01.70.60.9-0.9-0.9-1.2-0.9-1.31.2-1.20.0
Bone: maximum diameter1.42.75.7-2.4-2.02.02.01.81.80.9-1.00.90.0
Bone: maximum force6.210.917.8-4.2-3.93.83.83.64.02.6-2.52.40.0
Bone: maximum moment4.57.913.8-3.7-3.33.23.33.13.42.1-2.01.90.0
Mean time between licks in bursts0.82.03.9-2.0-1.61.71.71.71.70.9-0.80.70.0
Mean num. licks in bursts0.10.20.4-0.3-0.40.40.40.40.40.6-0.60.60.0
Cd content in liver0.20.20.7-0.8-0.20.10.1-0.00.1-0.60.7-0.70.0
Co content in liver0.00.00.1-0.3-0.30.10.10.20.00.2-0.30.30.0
Cu content in liver1.31.53.50.4-0.61.11.21.10.91.9-1.81.80.0
Fe content in liver0.70.91.81.11.1-0.9-1.0-1.3-1.1-0.70.8-0.70.0
K content in liver1.91.83.31.81.7-1.4-1.4-1.6-1.5-1.01.2-1.10.0
Mg content in liver0.10.10.20.40.3-0.2-0.2-0.3-0.3-0.20.2-0.20.0
Mn content in liver0.40.40.7-0.3-0.50.70.80.80.80.7-0.60.60.0
Na content in liver0.30.31.91.40.7-0.3-0.3-0.2-0.10.6-0.30.30.0
Rb content in liver0.70.82.1-0.70.2-0.6-0.7-0.8-0.8-1.41.2-1.30.0
Se content in liver0.40.40.80.0-0.40.80.80.40.60.9-0.80.80.0
Sr content in liver0.40.30.50.70.6-0.7-0.6-0.7-0.6-0.40.4-0.40.0
Zn content in liver0.10.20.30.1-0.20.50.50.20.30.5-0.50.50.0
Bone: minimum diameter1.22.24.2-2.1-1.81.81.81.81.71.0-1.00.90.0
Time in familiar zone, hab. session 10.00.00.1-0.3-0.30.30.20.10.20.1-0.20.20.0
Time in novel zone, hab. session 10.00.00.0-0.00.0-0.00.00.10.1-0.00.1-0.10.0
Total zone transitions, hab. session 10.20.31.00.4-0.10.60.60.30.61.0-0.70.80.0
Total locomotion distance, hab. session 10.60.82.10.8-0.20.80.90.50.81.4-1.21.30.0
Locomotion velocity, hab. session 10.50.71.80.9-0.00.70.70.40.61.3-1.11.10.0
Time in familiar zone, hab. session 20.00.00.1-0.1-0.0-0.00.00.0-0.3-0.10.1-0.10.0
Time in novel zone, hab. session 20.20.20.30.20.4-0.5-0.5-0.5-0.1-0.50.5-0.50.0
Total zone transitions, hab. session 20.10.10.20.30.00.40.30.10.10.5-0.30.30.0
Total locomotion distance, hab. session 21.21.63.3-0.2-0.91.51.41.11.31.8-1.51.50.0
Locomotion velocity, hab. session 21.21.63.5-0.1-0.91.51.41.11.31.9-1.51.60.0
Novel to familiar place preference ratio0.91.02.00.40.8-1.1-1.2-1.0-1.0-1.41.2-1.20.0
Novelty place preference1.21.32.20.61.0-1.3-1.3-1.1-1.1-1.51.3-1.30.0
Time in novel zone, NPP test1.31.42.10.81.2-1.3-1.3-1.2-1.2-1.41.3-1.30.0
Total zone transitions, NPP test0.40.51.50.5-0.20.70.60.40.61.2-1.01.00.0
Total locomotion distance, NPP test1.01.43.70.6-0.51.11.10.91.11.9-1.51.60.0
Locomotion velocity, NPP test0.70.92.80.7-0.30.90.90.60.91.7-1.31.30.0
Intraocular pressure0.20.21.3-1.1-0.50.10.20.3-0.1-0.60.4-0.50.0
Delta distance traveled before/after self-admin0.80.91.2-1.0-1.11.00.91.00.91.0-1.01.00.0
Delta ambulatory time before/after self-admin0.20.30.4-0.5-0.60.50.50.50.50.6-0.70.70.0
Parametrial fat weight0.41.02.4-1.5-0.2-0.5-0.5-0.3-0.3-1.41.4-1.50.0
Pavlov. Cond. lever latency5.87.310.51.92.7-2.9-2.8-3.0-2.7-3.23.2-3.20.0
Pavlov. Cond. magazine entry latency0.20.30.6-0.7-0.60.60.60.70.40.5-0.40.30.0
Pavlov. Cond. change in total contacts4.14.35.6-2.2-2.42.32.32.42.12.1-2.12.00.0
Pavlov. Cond. index score2.22.84.3-1.1-1.61.81.81.91.62.1-1.91.90.0
Pavlov. Cond. latency score3.34.16.4-1.3-2.02.22.12.32.02.5-2.32.40.0
Pavlov. Cond. lever contacts4.85.78.0-1.8-2.42.52.52.72.42.8-2.72.70.0
Pavlov. Cond. magazine entry number0.40.50.80.90.8-0.9-0.8-0.9-0.6-0.70.6-0.50.0
Pavlov. Cond. intertrial magazine entries1.41.72.6-0.7-1.21.31.31.31.51.6-1.61.60.0
Pavlov. Cond. lever-magazine prob. diff.1.82.23.3-1.1-1.51.61.61.71.41.8-1.61.60.0
Pavlov. Cond. response bias1.31.62.4-1.1-1.31.51.41.51.21.4-1.31.30.0
Pavlov. Cond. lever latency0.50.61.71.31.1-0.6-0.6-0.9-0.9-0.40.6-0.60.0
Pavlov. Cond. magazine entry latency0.40.51.7-1.3-1.00.30.30.60.60.3-0.60.60.0
Pavlov. Cond. change in total contacts0.60.92.2-1.5-1.30.80.81.11.10.7-0.80.80.0
Pavlov. Cond. index score0.60.82.6-1.6-1.30.60.61.01.00.4-0.70.70.0
Pavlov. Cond. latency score0.50.61.9-1.4-1.10.50.50.90.80.4-0.70.70.0
Pavlov. Cond. lever contacts0.50.71.6-1.3-1.10.60.61.00.90.5-0.70.70.0
Pavlov. Cond. magazine entry number0.81.03.41.81.5-0.8-0.8-1.1-1.1-0.50.7-0.70.0
Pavlov. Cond. intertrial magazine entries0.40.62.61.61.2-0.5-0.6-0.9-0.7-0.20.5-0.50.0
Pavlov. Cond. lever-magazine prob. diff.0.71.03.0-1.7-1.40.70.71.11.10.5-0.80.70.0
Pavlov. Cond. response bias0.60.82.1-1.4-1.20.70.71.01.10.5-0.70.70.0
Time in closed arm before self-admin2.53.28.7-3.0-2.41.81.92.01.71.1-1.11.00.0
Time in closed arm after self-admin0.60.62.4-1.5-0.5-0.1-0.2-0.0-0.1-1.21.0-1.00.0
Time in open arm before self-admin1.21.32.90.2-0.71.01.01.01.21.6-1.71.70.0
Time in open arm after self-admin3.03.37.40.0-1.21.71.91.71.72.7-2.42.50.0
Bone: periosteal estimation0.71.63.6-1.9-1.51.51.51.41.50.6-0.60.50.0
Bone: periosteal perimeter2.03.48.1-2.9-2.32.12.12.12.00.9-1.00.90.0
Bone: post-yield work0.00.10.20.2-0.00.30.30.10.40.5-0.20.20.0
Progressive ratio test 1 active lever presses0.81.03.2-1.8-1.41.11.10.90.70.3-0.70.70.0
Progressive ratio test 1 breakpoint0.80.92.9-1.7-1.41.01.10.90.70.3-0.70.70.0
Progressive ratio test 1 inactive lever presses0.71.02.1-1.5-1.21.21.21.00.90.7-0.60.50.0
Progressive ratio test 2 active lever presses0.30.31.1-0.40.2-0.4-0.4-0.5-0.6-1.00.7-0.80.0
Progressive ratio test 2 breakpoint0.30.31.0-0.30.2-0.5-0.4-0.5-0.6-1.00.7-0.80.0
Progressive ratio test 2 inactive lever presses0.20.21.1-1.1-0.70.50.50.50.40.1-0.20.10.0
Incentive Sensitization - Responses2.23.14.91.21.7-1.9-1.8-1.8-1.8-2.22.0-2.00.0
Incentive Sensitization - Breakpoint2.73.65.31.41.9-2.0-2.0-2.0-1.9-2.32.1-2.10.0
Sum of active levers in priming session hrs 5-60.50.52.61.61.0-0.5-0.5-0.6-0.30.20.00.10.0
Progressive ratio0.40.61.00.50.7-1.0-0.8-0.7-0.8-0.90.8-0.80.0
Food seeking constrained by brief footshock0.20.20.60.50.5-0.6-0.5-0.5-0.8-0.40.2-0.20.0
Seeking ratio, punishment vs. effort0.30.40.90.0-0.40.70.50.40.60.9-0.80.80.0
Retroperitoneal fat weight0.72.99.9-3.1-2.21.91.92.01.70.6-0.40.30.0
Reaction time number correct1.73.46.5-0.6-1.52.12.11.81.72.6-2.12.20.0
Reaction time mean minus median0.00.10.3-0.0-0.2-0.1-0.10.1-0.10.1-0.50.50.0
Reaction time mean minus median AUC0.00.10.3-0.1-0.30.10.10.1-0.10.1-0.50.50.0
Reaction time num false alarms0.20.31.0-1.0-0.80.30.20.40.3-0.0-0.60.60.0
Reaction time num false alarms AUC0.10.10.5-0.7-0.60.20.10.20.2-0.2-0.40.40.0
Reaction time trials correct on left1.73.46.5-0.6-1.52.12.11.81.72.6-2.12.20.0
Reaction time trials on left1.93.66.7-0.6-1.52.22.21.91.82.6-2.22.20.0
Reaction time mean0.81.33.2-0.10.6-1.2-1.2-1.0-1.2-1.81.3-1.40.0
Reaction time mean AUC1.21.93.70.41.1-1.5-1.6-1.4-1.6-1.91.5-1.50.0
Median of all reaction times1.72.45.40.11.1-1.6-1.6-1.5-1.6-2.32.0-2.00.0
Reaction time omissions0.50.71.4-1.2-1.20.60.80.60.50.2-1.11.10.0
Reaction time false alarm rate0.20.31.1-0.7-0.2-0.5-0.5-0.3-0.3-1.10.3-0.40.0
Reaction time premature initiation rate1.01.43.1-0.3-1.01.11.01.00.91.6-1.71.80.0
Reaction time premature initiations2.23.97.2-0.7-1.72.12.01.81.72.7-2.62.70.0
Std. dev. reaction times0.10.10.4-0.6-0.60.00.10.3-0.0-0.1-0.50.50.0
Reaction time trials completed1.93.66.7-0.6-1.52.22.21.91.82.6-2.22.20.0
Reaction time trials AUC1.73.25.9-0.7-1.52.12.11.81.72.4-2.02.10.0
Run reversals in cocaine runway, females1.00.93.0-1.7-1.31.01.01.00.90.4-0.70.60.0
Run reversals in cocaine runway, males0.20.20.80.90.3-0.4-0.5-0.3-0.00.4-0.50.50.0
Latency to leave start box in cocaine runway0.10.10.10.20.2-0.3-0.2-0.3-0.3-0.20.3-0.30.0
Latency to leave start box in cocaine runway, F0.30.40.5-0.6-0.70.70.70.50.70.7-0.60.60.0
Latency to leave start box in cocaine runway, M3.02.83.71.41.7-1.9-1.8-1.8-1.8-1.81.8-1.80.0
Std. dev. time between licks in bursts0.91.22.8-1.7-1.41.31.31.21.30.6-0.70.60.0
Total sessions with >9 infusions0.91.14.4-2.1-1.41.11.21.00.90.2-0.30.20.0
Short access day 1 total inactive lever presses0.50.62.1-0.60.3-0.5-0.4-0.5-0.4-1.11.4-1.40.0
Short access day 10 total inactive lever presses0.00.10.20.40.3-0.2-0.3-0.2-0.3-0.10.2-0.20.0
Short access day 1 total infusions1.11.44.4-2.1-1.51.41.51.21.10.6-0.30.30.0
Short access day 10 total infusions0.10.20.6-0.8-0.40.60.60.40.20.10.2-0.30.0
Short access total infusions0.20.31.5-1.2-0.50.50.60.30.2-0.30.4-0.50.0
Short access day 1 locomotion1.11.46.4-2.5-1.51.21.31.00.8-0.10.1-0.20.0
Short access day 10 total locomotion2.75.17.0-2.2-2.52.62.62.52.02.4-2.22.20.0
Short access total locomotion1.31.64.1-2.0-1.61.51.51.41.10.7-0.80.70.0
One hour access (0.3 mA shock)0.50.61.4-0.10.5-0.5-0.5-0.7-1.0-1.11.1-1.20.0
Compulsive drug intake1.72.02.71.61.7-1.5-1.5-1.5-1.5-1.31.4-1.40.0
One hour access (shock baseline)0.20.42.2-1.5-0.80.50.50.40.2-0.30.2-0.30.0
Social response proportion2.22.54.8-2.2-2.11.61.51.81.51.2-1.51.50.0
Social responses2.22.83.7-1.3-1.71.91.81.91.71.9-1.91.90.0
Social time0.60.81.3-0.7-0.91.11.21.11.00.9-0.90.90.0
Soleus weight0.20.41.2-0.9-0.1-0.4-0.4-0.6-0.1-1.10.9-1.00.0
Bone: stiffness4.37.012.5-3.5-3.13.03.02.93.01.9-2.01.90.0
Tibialis anterior weight1.24.15.7-1.5-2.02.02.02.32.22.4-2.32.30.0
Time to tail flick, vehicle, before self-admin1.41.52.20.91.2-1.2-1.4-1.5-1.3-1.51.2-1.20.0
Time to tail flick, vehicle, after self-admin0.10.10.3-0.6-0.40.20.40.40.60.30.1-0.10.0
Time to tail flick, test, before self-admin0.50.52.0-1.4-1.10.60.60.60.6-0.1-0.40.40.0
Time to tail flick, test, after self-admin3.03.14.01.61.9-1.9-1.9-2.0-1.7-2.01.9-1.90.0
Delta time to tail flick, vehicle, before/after SA0.80.71.5-0.5-0.80.80.91.11.11.2-0.70.70.0
Delta time to tail flick, test, before/after SA1.81.93.21.81.8-1.3-1.4-1.4-1.4-1.11.4-1.40.0
Tibia length0.82.23.5-1.9-1.81.61.61.61.51.3-1.41.30.0
Ambulatory time before self-admin1.21.72.9-1.7-1.61.41.41.31.51.1-1.21.10.0
Ambulatory time after self-admin4.24.96.7-2.4-2.62.42.32.22.32.2-2.32.30.0
Bone: tissue strength0.10.10.2-0.2-0.20.40.50.30.40.2-0.10.10.0
Total heroin consumption0.00.10.2-0.2-0.30.20.1-0.1-0.0-0.1-0.40.40.0
Bone: trabecular number2.13.55.0-2.1-2.21.91.91.81.91.7-2.02.00.0
Bone: trabecular spacing0.60.91.20.91.0-0.9-1.0-1.1-0.8-0.91.1-1.10.0
Bone: trabecular thickness2.32.93.6-1.6-1.91.81.81.91.91.7-1.81.80.0
Bone: trabecular tissue density0.20.20.70.60.10.50.50.30.60.8-0.40.40.0
Water consumed over 24 hours0.81.11.8-0.5-0.91.00.91.01.21.2-1.31.40.0
Number of responses in last shaping day0.40.40.9-0.6-0.60.80.90.70.50.8-0.50.50.0