Hub : Genes

Coch

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Coch 0.31 0.18 8.8e-03 0 0.03 -0 0.02 3.2e-01 1.3e-01 3.6e-01 1.8e-01
2 NAcc gene expression Coch 0.24 0.13 0.0e+00 0.17 0.17 0.17 0.17 1.6e-25 1.6e-25 1.6e-25 1.8e-25
3 NAcc mRNA stability Coch 0.08 0.05 5.7e-07 0.03 0.03 0.04 0.04 5.9e-05 7.1e-06 4.3e-06 3.2e-06
4 IL gene expression Coch 0.23 0.14 4.2e-04 0.12 0.08 0.04 0.07 8.8e-04 6.1e-03 3.5e-02 1.1e-02
5 NAcc alternative TSS NM_001108710.2 0.02 0.02 1.5e-03 0.02 0.01 0.01 0.01 1.6e-03 5.8e-03 2.2e-03 5.6e-03
6 Brain mRNA stability Coch 0.03 0.03 6.9e-03 0.02 0.01 0.01 0.01 1.1e-02 1.3e-02 3.2e-02 2.8e-02
7 pVTA gene expression Coch 0.09 0.05 6.9e-07 0.07 0.07 0.08 0.07 2.2e-06 1.4e-06 1.1e-06 2.7e-06
8 LHb gene expression Coch 0.14 0.1 6.0e-03 0.01 0.07 0.01 0.03 1.4e-01 1.1e-02 2.1e-01 6.5e-02
9 IC gene expression Coch 0.32 0.12 9.9e-12 0.25 0.27 0.25 0.26 7.2e-11 1.4e-11 8.5e-11 3.6e-11
10 PL gene expression Coch 0.17 0.07 0.0e+00 0.18 0.18 0.19 0.19 7.2e-19 1.0e-19 2.8e-20 5.4e-20
11 Brain gene expression Coch 0.59 0.12 0.0e+00 0.48 0.58 0.58 0.58 5.0e-51 1.6e-65 1.3e-65 2.5e-65
12 OFC alternative TSS XM_063262103.1 0.21 0.15 2.4e-03 0.09 0.1 0.09 0.1 4.5e-03 2.8e-03 3.7e-03 3.0e-03
13 Liver alternative TSS XM_063262102.1 0.02 0.02 9.9e-03 0.01 0.02 0.01 0.01 2.8e-02 5.6e-03 3.9e-02 2.7e-02
14 OFC alternative TSS XM_063262103.1 0.17 0.12 6.2e-03 0.05 0.06 0.05 0.07 2.2e-02 1.3e-02 3.1e-02 9.2e-03
15 Brain isoform ratio XM_063262102.1 0.06 0.04 2.0e-04 0.02 0.04 0.03 0.03 5.0e-03 6.9e-05 2.1e-03 9.4e-04
16 Liver gene expression Coch 0.47 0.13 0.0e+00 0.45 0.46 0.46 0.46 4.9e-55 5.3e-56 1.3e-56 1.2e-56
17 Brain isoform ratio NM_001108710.2 0.07 0.05 6.8e-05 0.01 0.05 0.03 0.03 5.6e-02 3.3e-05 3.6e-04 1.1e-03
18 BLA gene expression Coch 0.35 0.13 5.6e-17 0.29 0.29 0.26 0.29 1.2e-15 1.6e-15 6.1e-14 8.4e-16
19 OFC gene expression Coch 0.25 0.15 5.8e-04 0.18 0.08 0.14 0.13 5.5e-05 7.3e-03 4.4e-04 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.52.75.4-2.3-2.3-0.8-2.3-1.6-1.6-2.2-2.0-2.0-2.1-1.9-1.5-1.5-1.2-0.5-0.70.6-0.8-0.6
Area under the delay curve1.41.63.50.10.1-1.50.2-1.5-1.60.60.80.81.00.91.31.41.6-1.91.51.91.80.6
BMI with tail1.13.85.8-1.7-1.71.6-1.70.20.4-2.1-2.3-2.3-2.0-2.3-2.4-2.4-2.41.4-2.2-1.4-2.3-2.1
BMI without tail2.37.011.0-2.6-2.61.6-2.5-0.00.1-3.0-3.2-3.2-3.1-3.3-3.3-3.3-2.81.8-2.8-1.8-3.0-2.8
Body weight1.77.614.9-3.9-3.8-0.5-3.8-2.5-2.4-3.8-3.5-3.6-3.3-3.5-2.8-2.7-1.7-0.5-1.50.5-1.6-1.4
Weight adjusted by age0.40.63.20.90.91.80.91.21.20.80.50.40.70.5-0.00.0-0.20.8-0.3-0.7-0.1-0.0
Bone surface1.12.06.0-1.4-1.4-2.4-1.4-2.4-2.3-1.0-0.4-0.5-0.7-0.40.40.40.9-2.01.32.01.11.3
Bone volume1.22.15.4-2.0-1.9-1.8-1.9-2.3-2.3-1.6-1.2-1.2-1.3-1.1-0.4-0.3-0.1-1.70.51.70.40.6
Breakpoint value in progressive ratio session1.61.94.2-2.1-1.9-1.0-1.9-1.9-1.8-1.8-1.5-1.6-1.6-1.4-1.0-0.9-0.6-1.1-0.21.1-0.2-0.1
Number of licking bursts0.00.10.10.30.30.40.30.30.40.20.20.20.20.20.10.00.00.3-0.1-0.3-0.1-0.1
Context. condit. distance diff. score0.70.83.0-0.4-0.21.5-0.20.60.7-0.5-0.8-0.8-0.6-0.6-1.2-1.1-1.70.8-1.3-0.8-0.9-0.9
Locomotion velocity, session 10.10.10.3-0.10.0-0.50.0-0.5-0.40.00.10.10.10.20.10.2-0.0-0.60.30.60.50.4
Locomotion distance, session 11.01.22.61.61.60.71.61.51.41.51.21.21.31.20.80.70.20.80.1-0.80.10.2
Locomotion velocity, session 22.22.54.21.91.8-0.41.80.50.52.12.12.11.92.01.91.91.5-0.61.40.51.41.5
Locomotion distance, session 21.82.65.52.32.20.32.21.51.52.22.02.01.91.91.71.51.10.50.8-0.50.70.8
Locomotion velocity, session 31.92.23.81.91.9-0.41.91.10.81.91.91.91.71.91.71.61.3-0.11.20.01.11.1
Locomotion distance, session 30.50.62.20.90.70.70.71.51.30.50.40.40.10.30.1-0.1-0.11.2-0.4-1.3-0.7-0.7
Stereotopy head waving bouts, day 32.12.54.11.82.0-0.52.00.50.42.02.02.02.02.01.71.81.3-0.61.40.61.61.5
Stereotopy head waving duration, day 31.82.13.41.51.7-0.71.70.30.11.71.81.81.81.81.61.71.3-0.81.40.81.61.5
Locomotion velocity, session 72.73.07.70.70.62.60.62.52.50.1-0.4-0.4-0.2-0.5-1.3-1.4-1.62.8-2.1-2.8-2.2-2.1
Locomotion distance, session 72.93.67.9-0.1-0.22.4-0.22.12.2-0.8-1.2-1.2-1.4-1.3-1.8-2.0-1.92.8-2.5-2.8-2.6-2.6
Stereotopy head waving bouts, day 70.60.71.30.30.4-1.10.4-0.6-0.70.60.70.70.60.80.80.90.7-1.01.11.01.11.1
Stereotopy head waving duration, day 71.61.93.31.01.1-1.41.1-0.4-0.51.31.51.51.41.61.61.71.4-1.31.71.31.81.7
Locomotion velocity, session 80.30.40.80.30.5-0.60.50.0-0.30.60.60.60.90.80.50.60.3-0.60.70.70.90.9
Locomotion distance, session 80.30.40.90.80.90.70.90.90.90.70.50.50.50.60.10.2-0.30.6-0.3-0.6-0.1-0.0
Degree of sensitization distance0.40.40.6-0.6-0.60.6-0.6-0.20.0-0.7-0.8-0.8-0.7-0.8-0.8-0.8-0.70.3-0.8-0.3-0.6-0.7
Degree of sensitization stereotypy0.50.51.5-0.7-0.6-1.2-0.6-1.2-1.2-0.4-0.2-0.2-0.4-0.10.20.30.3-1.10.71.10.70.7
Conditioned locomotion1.82.13.41.61.7-0.71.70.40.51.81.81.81.71.81.61.61.5-0.51.40.51.41.3
Cocaine response after cond. corrected0.20.30.70.20.10.80.10.70.8-0.0-0.2-0.2-0.2-0.2-0.4-0.4-0.50.8-0.7-0.8-0.7-0.6
Cocaine response after cond. not corrected1.01.22.2-0.5-0.61.1-0.60.70.8-0.8-1.0-1.0-1.0-1.1-1.3-1.3-1.31.3-1.5-1.3-1.5-1.4
Cocaine response before conditioning1.01.21.9-0.9-1.00.7-1.00.30.2-1.1-1.3-1.3-1.2-1.3-1.3-1.4-1.20.9-1.3-0.9-1.3-1.3
Saline control response0.91.22.5-1.6-1.5-0.3-1.5-1.0-1.1-1.4-1.4-1.4-1.0-1.3-1.1-1.1-0.8-0.3-0.50.3-0.5-0.6
Bone: connectivity density3.25.09.8-3.1-3.1-1.2-3.1-2.0-1.9-3.0-2.8-2.8-3.0-2.7-2.1-2.1-1.3-0.5-1.10.4-1.4-1.1
Bone: cortical apparent density1.11.54.80.0-0.12.2-0.11.31.3-0.2-0.7-0.7-0.5-0.7-1.3-1.2-1.71.6-1.7-1.6-1.5-1.5
Bone: cortical area1.62.46.9-1.2-1.3-2.4-1.3-2.6-2.5-0.8-0.2-0.2-0.6-0.20.80.81.6-2.31.72.21.41.5
Bone: cortical porosity1.51.63.30.30.3-1.80.3-1.0-1.20.61.01.00.81.01.51.41.8-1.61.71.51.61.5
Bone: cortical porosity1.51.74.00.30.2-2.00.2-1.0-1.30.61.01.00.71.01.61.52.0-1.51.81.51.61.5
Bone: cortical thickness0.20.41.0-0.8-1.0-0.4-1.0-0.9-0.7-0.8-0.6-0.6-0.8-0.7-0.2-0.30.1-0.30.00.3-0.2-0.1
Bone: cortical thickness0.10.10.50.40.30.60.30.70.60.30.20.20.30.1-0.0-0.0-0.30.5-0.2-0.5-0.3-0.1
Bone: cortical tissue density1.11.54.90.0-0.02.2-0.01.31.3-0.2-0.7-0.7-0.4-0.7-1.3-1.2-1.81.6-1.7-1.6-1.5-1.4
Condit. Reinf. active minus inactive responses1.31.44.3-1.4-1.5-2.1-1.5-2.0-1.8-1.2-0.7-0.7-1.2-0.80.1-0.00.7-1.30.71.30.40.4
Condit. Reinf. active-inactive response ratio0.20.20.4-0.5-0.6-0.6-0.6-0.6-0.4-0.5-0.4-0.4-0.5-0.4-0.1-0.2-0.0-0.30.10.3-0.0-0.1
Condit. Reinf. active responses1.82.27.8-1.4-1.5-2.8-1.5-2.4-2.3-1.1-0.5-0.5-1.0-0.50.50.41.3-1.91.31.90.91.0
Condit. Reinf. inactive responses0.60.83.2-0.5-0.5-1.8-0.5-1.2-1.3-0.30.10.0-0.20.00.60.51.3-1.21.01.10.80.8
Incentive salience index mean1.72.18.4-1.1-1.3-2.9-1.3-2.3-2.2-0.9-0.2-0.2-0.9-0.40.80.61.7-1.91.51.81.11.0
Condit. Reinf. lever presses0.50.73.3-0.1-0.3-1.8-0.3-1.0-0.9-0.10.40.3-0.20.21.00.81.7-0.91.20.80.80.7
Condit. Reinf. active minus inactive responses0.10.10.30.50.5-0.10.50.50.50.40.40.40.30.40.30.30.30.30.1-0.30.1-0.0
Condit. Reinf. active-inactive response ratio0.30.40.60.80.8-0.10.80.40.40.80.70.70.70.80.60.60.6-0.00.50.00.50.5
Condit. Reinf. active responses0.10.20.40.60.6-0.30.60.60.60.50.50.50.30.50.40.30.50.30.2-0.30.1-0.0
Condit. Reinf. inactive responses0.20.30.6-0.3-0.30.1-0.30.40.4-0.4-0.5-0.5-0.5-0.6-0.6-0.6-0.50.6-0.7-0.6-0.7-0.8
Condit. Reinf. lever presses0.50.62.2-1.1-1.0-1.5-1.0-1.1-1.2-0.8-0.7-0.6-0.6-0.6-0.3-0.20.3-0.80.20.80.10.1
Condit. Reinf. lever reinforcers received0.20.31.8-0.1-0.1-1.4-0.1-0.5-0.6-0.00.20.2-0.00.20.50.50.9-0.70.70.60.60.5
Conditioned reinforcement - actives1.01.87.5-1.2-1.1-2.7-1.0-2.1-2.1-0.7-0.3-0.3-0.7-0.20.50.51.0-1.91.21.91.00.8
Conditioned reinforcement - inactives1.42.04.6-2.1-2.0-1.9-2.0-1.5-1.7-1.7-1.6-1.6-1.4-1.5-1.1-1.0-0.8-0.9-0.30.9-0.4-0.6
Conditioned locomotion0.10.10.6-0.2-0.3-0.7-0.3-0.2-0.3-0.2-0.0-0.0-0.5-0.10.20.10.3-0.30.30.20.10.3
Patch foraging indifference point 0 sec1.42.58.6-1.2-1.3-2.9-1.3-2.8-2.4-0.9-0.2-0.2-0.8-0.20.80.71.4-2.21.62.11.31.6
Patch foraging indifference point AUC2.33.311.80.10.1-3.40.1-1.7-2.00.71.21.20.91.12.01.92.5-2.32.52.22.11.8
Delay disc. indifference point, 0s delay0.50.51.7-0.2-0.1-0.4-0.1-1.0-1.00.30.30.31.00.40.40.60.2-1.20.81.30.91.1
Delay disc. indifference point, 16s delay1.61.83.60.40.4-1.40.5-1.4-1.30.91.11.01.11.11.51.51.8-1.81.71.81.91.1
Delay disc. indifference point, 2s delay0.30.31.1-0.3-0.4-1.1-0.3-1.0-1.0-0.00.10.10.30.10.40.40.6-0.90.60.90.60.1
Delay disc. indifference point, 24s delay2.22.55.8-0.20.0-2.30.1-2.0-2.20.40.80.80.90.91.51.51.9-2.41.92.42.21.2
Delay disc. indifference point, 4s delay0.60.71.10.90.9-0.01.00.20.01.01.01.01.11.01.00.91.0-0.30.90.31.00.4
Delay disc. indifference point, 8s delay0.30.41.2-0.3-0.3-1.1-0.2-0.9-1.0-0.10.10.1-0.10.10.60.50.9-0.90.60.80.7-0.6
Indifference point function ln k0.40.71.9-0.3-0.41.4-0.40.50.6-0.6-0.8-0.8-0.7-0.7-1.0-1.0-1.10.9-1.1-0.9-1.0-0.7
Indifference point function log k0.40.71.9-0.3-0.41.4-0.40.50.6-0.6-0.8-0.8-0.7-0.7-1.0-1.0-1.10.9-1.1-0.9-1.0-0.7
Patch foraging total patch changes 0 sec1.63.010.3-1.2-1.3-3.2-1.3-3.0-2.6-0.9-0.1-0.1-0.7-0.11.00.91.6-2.41.92.41.51.9
Patch foraging total patch changes 12 sec2.33.012.4-1.1-1.2-3.5-1.3-2.8-2.7-0.8-0.0-0.0-0.6-0.11.11.01.9-2.41.92.31.51.5
Patch foraging total patch changes 18 sec0.61.04.5-0.5-0.6-2.1-0.5-1.5-1.4-0.30.10.1-0.5-0.00.80.61.4-1.21.21.10.90.8
Patch foraging total patch changes 24 sec0.81.46.9-0.5-0.7-2.6-0.6-1.6-1.7-0.20.30.3-0.10.21.00.91.6-1.61.51.51.11.2
Patch foraging total patch changes 6 sec1.72.511.5-1.3-1.4-3.4-1.4-2.6-2.3-0.9-0.3-0.3-0.8-0.30.80.71.4-2.11.52.11.21.2
Patch foraging time to switch 0 sec6.312.834.40.70.75.90.74.84.8-0.3-1.5-1.5-1.0-1.6-3.3-3.3-4.45.2-4.7-5.2-4.4-4.2
Patch foraging water rate 0 sec2.04.312.0-0.2-0.3-3.5-0.3-2.8-2.50.31.00.90.61.02.02.02.7-2.92.82.82.42.6
Patch foraging water rate 12 sec0.61.42.8-1.7-1.6-1.2-1.6-1.6-1.4-1.5-1.2-1.3-1.5-1.2-0.7-0.7-0.2-0.80.00.8-0.1-0.0
Patch foraging water rate 18 sec0.71.03.1-0.8-1.0-1.3-0.9-1.8-1.6-0.5-0.2-0.2-0.3-0.10.30.40.8-1.61.01.60.91.2
Patch foraging water rate 24 sec0.60.82.4-0.6-0.7-1.6-0.6-1.5-1.3-0.4-0.1-0.1-0.4-0.20.50.41.0-1.21.01.20.80.9
Patch foraging water rate 6 sec2.73.910.9-0.9-0.9-3.3-0.8-3.0-3.1-0.40.40.3-0.10.41.51.42.3-2.92.42.92.22.3
Seeking ratio, delayed vs. immediate footshock1.01.32.51.61.40.11.40.70.61.31.41.41.21.31.41.21.50.20.9-0.20.70.5
Distance traveled before self-admin0.20.31.20.40.3-0.60.3-0.1-0.30.50.50.50.40.40.80.61.1-0.40.60.30.5-0.2
Distance traveled after self-admin0.10.10.90.10.01.00.00.40.30.1-0.1-0.10.2-0.1-0.3-0.2-0.30.3-0.5-0.3-0.4-0.7
Extensor digitorum longus weight3.011.722.3-4.7-4.5-0.0-4.5-2.6-2.4-4.5-4.4-4.4-4.1-4.2-3.8-3.6-3.0-0.3-2.40.4-2.3-2.2
Bone: elastic displacement1.21.42.7-0.9-0.90.6-0.90.60.5-1.0-1.3-1.3-1.2-1.3-1.5-1.5-1.21.2-1.5-1.2-1.6-1.5
Bone: elastic work2.33.05.5-1.6-1.70.4-1.70.20.2-1.9-2.0-2.0-2.3-2.2-1.9-2.1-1.31.3-1.9-1.3-2.3-2.0
Bone: endosteal estimation2.45.39.70.70.8-2.60.8-2.1-1.91.31.91.91.62.02.62.72.8-2.93.12.93.13.1
Bone: endosteal perimeter3.16.612.50.30.2-3.50.2-2.8-2.71.01.71.71.31.82.82.83.3-3.53.53.53.43.4
Epididymis fat weight0.62.13.8-0.9-0.91.8-1.00.70.9-1.1-1.5-1.5-1.1-1.5-1.9-1.8-2.01.4-1.9-1.3-1.8-1.5
Delta time in closed arm before/after self-admin0.50.41.0-0.9-1.0-0.5-1.0-0.4-0.7-0.9-0.8-0.8-1.0-0.9-0.5-0.6-0.10.0-0.2-0.0-0.4-0.2
Delta time in open arm before/after self-admin0.20.21.1-0.5-0.30.1-0.30.10.3-0.3-0.5-0.5-0.1-0.4-0.7-0.6-1.00.1-0.6-0.1-0.3-0.6
Diff in mean of infusions in LGA sessions0.30.40.80.80.90.80.90.80.80.90.70.70.80.60.40.40.10.2-0.1-0.20.1-0.1
Delay discount exponential model param1.31.53.2-0.3-0.31.4-0.41.31.4-0.7-0.9-0.9-1.0-1.0-1.4-1.4-1.71.7-1.5-1.6-1.8-0.5
Extinction: sum of active levers before priming3.94.39.4-2.7-3.0-0.9-3.0-1.4-1.4-2.9-2.6-2.6-3.1-2.7-1.9-2.1-1.00.2-1.2-0.2-1.7-1.2
Active lever presses in extinction session 63.23.26.6-2.5-2.6-1.5-2.5-1.7-1.7-2.5-2.1-2.1-2.3-2.2-1.4-1.5-1.0-0.6-0.60.5-0.9-0.6
Bone: final force0.00.00.10.1-0.00.0-0.0-0.2-0.10.10.20.20.10.10.30.20.3-0.20.30.20.20.4
Bone: final moment0.10.10.30.1-0.0-0.1-0.0-0.3-0.30.10.20.20.20.20.40.40.4-0.50.50.40.40.5
Food consumed during 24 hour testing period0.40.61.7-0.8-0.9-1.2-0.9-1.3-1.3-0.6-0.3-0.3-0.4-0.30.20.10.6-1.00.61.00.50.4
Glucose2.03.16.4-2.5-2.5-1.3-2.5-2.0-1.9-2.3-2.1-2.1-2.2-2.0-1.4-1.4-0.7-0.9-0.50.9-0.7-0.6
Heart weight0.71.13.0-1.5-1.3-1.6-1.4-1.7-1.6-1.2-0.9-0.9-1.0-0.8-0.3-0.30.4-1.10.51.10.20.6
Delay discount hyperbolic model param1.21.32.8-0.3-0.31.4-0.41.21.3-0.6-0.9-0.9-0.9-0.9-1.4-1.3-1.61.5-1.4-1.5-1.7-0.5
Intermittent access intake day 1-15 change1.32.75.0-2.2-2.2-0.2-2.2-0.7-1.1-2.0-2.1-2.1-1.8-2.1-1.9-1.8-1.40.1-1.3-0.1-1.3-1.7
Intermittent access intake escalation1.02.03.6-1.9-1.9-0.3-1.8-0.5-0.9-1.7-1.8-1.8-1.5-1.8-1.6-1.5-1.10.1-1.0-0.1-1.0-1.6
Intermittent access intake escalation 21.41.63.6-1.5-1.5-0.6-1.4-0.2-0.3-1.6-1.6-1.6-1.9-1.7-1.4-1.5-1.00.6-1.0-0.6-1.2-1.3
Intermitt. access day 1 inactive lever presses0.10.52.0-1.0-1.00.1-0.9-1.0-1.4-0.8-0.8-0.8-0.5-0.8-0.3-0.40.4-0.6-0.10.6-0.0-0.5
Intermitt. access day 15 inactive lever presses0.91.96.8-1.2-1.1-1.5-1.2-2.2-2.6-0.2-0.2-0.20.5-0.00.30.60.7-2.41.12.51.31.3
Intermitt. access escalation Index0.00.00.2-0.0-0.10.4-0.0-0.3-0.1-0.1-0.1-0.1-0.4-0.1-0.1-0.1-0.2-0.0-0.10.00.10.2
Intermittent access day 1 total infusions0.50.74.1-0.4-0.7-2.0-0.7-1.2-1.2-0.40.10.1-0.5-0.10.80.51.4-0.91.00.90.50.4
Intermittent access day 15 total infusions1.11.64.0-1.7-2.0-1.8-1.9-1.2-1.5-1.5-1.3-1.3-1.4-1.4-0.6-0.80.2-0.6-0.10.5-0.4-0.9
Intermittent access terminal intake (last 3 days)1.11.45.5-1.6-1.7-2.3-1.7-1.3-1.6-1.3-1.1-1.0-1.4-1.2-0.3-0.50.6-0.70.30.7-0.1-0.5
Intermittent access total infusions0.91.03.1-1.3-1.5-1.7-1.5-1.1-1.3-1.2-0.9-0.9-1.2-1.0-0.3-0.40.5-0.60.20.5-0.2-0.6
Intermittent access day 1 locomotion1.11.44.1-0.6-0.9-2.0-0.8-1.7-1.8-0.40.10.0-0.40.00.90.71.7-1.61.41.51.11.1
Intermittent access day 15 total locomotion0.61.12.8-1.3-1.4-0.3-1.3-0.6-0.5-1.5-1.3-1.3-1.7-1.3-1.0-1.1-0.50.1-0.6-0.1-0.8-0.8
Intermittent access total locomotion0.70.92.3-1.3-1.4-0.8-1.4-1.0-1.0-1.3-1.1-1.1-1.5-1.0-0.5-0.70.3-0.3-0.00.3-0.3-0.4
Intermittent access standard deviation0.61.22.8-1.7-1.6-1.2-1.6-1.2-1.6-1.2-1.2-1.2-1.0-1.1-0.7-0.7-0.1-0.9-0.00.9-0.0-0.6
Left kidney weight0.52.14.4-2.1-1.90.4-1.9-1.2-1.4-1.7-1.9-1.9-1.2-1.6-1.9-1.5-1.7-0.6-1.00.7-0.7-0.6
Right kidney weight0.42.04.0-1.8-1.70.9-1.6-0.7-0.7-1.5-1.9-1.9-1.0-1.7-2.0-1.7-1.90.1-1.40.0-1.0-1.1
Cocaine induced anxiety2.13.06.31.11.4-2.01.3-0.6-0.81.61.81.81.71.82.02.12.0-1.62.21.52.02.5
Post-drug Anxiety2.62.86.10.81.1-2.10.9-0.9-1.01.41.61.61.61.61.91.91.9-1.82.21.82.02.5
Baseline Anxiety0.50.61.5-0.5-0.60.9-0.60.30.4-0.6-0.7-0.7-0.7-0.7-0.9-0.9-1.10.7-1.1-0.7-0.9-1.2
Tail length1.03.98.0-2.8-2.8-0.9-2.7-2.0-2.1-2.8-2.5-2.5-2.7-2.4-1.8-1.8-0.7-0.6-0.80.6-0.9-1.1
Length with tail1.25.212.2-3.3-3.2-2.3-3.1-3.4-3.5-2.8-2.3-2.3-2.2-2.1-1.1-1.10.2-2.10.42.10.20.4
Length without tail0.82.78.0-1.4-1.3-2.3-1.4-2.8-2.8-0.8-0.3-0.4-0.2-0.20.50.71.1-2.61.62.61.51.7
Times rat made contact with spout0.60.62.80.30.31.70.31.11.10.0-0.2-0.2-0.0-0.2-0.6-0.6-1.01.1-0.9-1.1-0.9-0.9
Lifetime Intake0.91.12.5-1.4-1.6-1.5-1.5-1.0-1.1-1.3-1.1-1.0-1.3-1.1-0.5-0.60.2-0.5-0.00.4-0.4-0.7
Liver weight, left2.64.47.6-2.7-2.70.4-2.7-1.5-1.4-2.7-2.7-2.7-2.6-2.6-2.3-2.3-1.70.1-1.5-0.0-1.5-1.8
Liver weight, right2.95.18.4-2.0-2.12.0-2.00.30.4-2.2-2.6-2.7-2.1-2.6-2.9-2.8-2.81.6-2.7-1.6-2.5-2.5
Locomotor activity4.16.514.2-3.6-3.4-3.1-3.4-3.6-3.8-3.2-2.4-2.5-2.8-2.4-1.2-1.1-0.2-2.30.42.30.20.4
Locomotor testing distance3.05.411.4-3.4-3.3-2.1-3.3-2.5-2.7-3.1-2.7-2.7-3.0-2.7-1.8-1.7-1.0-1.1-0.51.1-0.8-0.3
Locomotor testing rearing3.57.113.7-3.5-3.6-1.3-3.6-1.6-1.6-3.5-3.3-3.3-3.7-3.4-2.7-2.7-1.90.2-1.7-0.2-2.1-2.0
Locomotion in novel chamber1.01.34.71.11.10.90.92.22.10.70.40.50.30.2-0.1-0.3-0.61.9-1.0-1.9-1.1-1.0
Locomotion in novel chamber post-restriction1.11.83.11.71.6-0.21.50.40.41.71.81.81.71.71.81.61.5-0.31.10.31.20.6
Fecal boli incidents, locomotor time 11.92.85.1-2.2-2.20.3-2.3-0.8-0.9-2.2-2.2-2.2-2.2-2.1-1.9-1.9-1.50.2-1.3-0.2-1.4-0.8
Change in fecal boli incidents, locomotor task0.10.10.2-0.2-0.1-0.0-0.1-0.20.1-0.2-0.2-0.2-0.4-0.2-0.3-0.2-0.20.1-0.3-0.1-0.3-0.5
Time >=10cm from walls, locomotor time 10.30.31.3-0.5-0.3-0.8-0.3-1.1-0.8-0.4-0.2-0.2-0.6-0.10.10.10.4-0.70.50.70.40.3
Bouts of movement, locomotor time 10.91.03.3-0.5-0.3-1.2-0.3-1.7-1.50.00.30.20.30.50.60.80.6-1.81.11.81.11.5
Total resting periods, locomotor time 11.11.34.0-0.4-0.1-1.4-0.1-1.8-1.60.10.40.40.40.60.71.00.8-2.01.32.01.41.4
Rest time, locomotor task time 11.92.35.20.30.6-1.50.6-1.7-1.60.71.21.20.91.41.51.71.5-2.31.92.32.11.9
Distance moved, locomotor task time 10.71.12.2-0.4-0.50.9-0.40.71.2-0.7-0.9-0.9-0.8-1.0-1.2-1.3-1.31.5-1.2-1.5-1.4-1.0
Vertical activity count, locomotor time 10.81.93.3-0.9-1.10.9-1.10.50.9-1.1-1.4-1.4-1.2-1.5-1.7-1.7-1.71.5-1.7-1.5-1.8-1.6
Time >=10cm from walls, locomotor time 20.60.92.0-1.3-1.3-1.2-1.3-1.2-1.1-1.2-1.1-1.1-1.4-1.2-0.6-0.70.2-0.30.10.3-0.40.0
Bouts of movement, locomotor time 20.20.30.60.30.3-0.60.2-0.5-0.40.40.60.60.30.50.80.80.8-0.70.70.70.70.2
Total resting periods, locomotor time 20.10.20.40.40.4-0.10.3-0.3-0.20.40.50.50.30.50.60.60.5-0.40.50.40.50.1
Rest time, locomotor task time 20.00.00.4-0.1-0.00.6-0.1-0.1-0.1-0.1-0.1-0.10.1-0.0-0.2-0.1-0.3-0.1-0.30.1-0.0-0.4
Distance moved, locomotor task time 20.20.21.6-0.1-0.0-1.30.0-0.6-0.1-0.00.10.1-0.20.10.30.30.4-0.30.60.30.40.7
Vertical activity count, locomotor time 20.10.10.20.40.3-0.40.30.20.40.40.30.40.20.30.30.20.10.20.3-0.20.00.3
Light reinforcement 10.51.32.6-1.2-1.30.2-1.3-0.1-0.2-1.5-1.4-1.4-1.6-1.5-1.3-1.4-1.00.6-1.1-0.7-1.2-1.2
Light reinforcement 21.32.14.11.41.3-0.51.2-0.0-0.21.51.71.71.51.61.91.82.0-0.91.70.91.61.5
Bone: marrow area2.45.39.80.70.8-2.70.8-2.2-1.91.21.91.91.62.02.62.72.8-3.03.13.03.13.1
Bone: maximum diameter4.07.415.4-0.2-0.3-3.9-0.3-3.5-3.20.61.51.41.01.42.72.73.5-3.93.73.93.43.5
Bone: maximum force0.40.71.30.10.0-0.90.0-0.9-0.90.30.50.50.40.50.90.91.1-1.11.11.11.11.1
Bone: maximum moment0.50.81.70.10.1-1.00.1-0.9-0.90.40.60.60.50.71.01.01.1-1.31.31.31.31.3
Mean time between licks in bursts0.00.10.5-0.4-0.10.0-0.1-0.3-0.2-0.1-0.2-0.20.30.0-0.5-0.2-0.7-0.4-0.10.50.20.2
Mean num. licks in bursts0.20.30.6-0.5-0.50.5-0.50.1-0.0-0.6-0.6-0.6-0.6-0.6-0.7-0.6-0.80.3-0.6-0.2-0.5-0.5
Cd content in liver1.41.62.9-1.4-1.50.5-1.5-0.4-0.3-1.6-1.5-1.5-1.7-1.6-1.4-1.4-1.30.5-1.2-0.5-1.2-1.1
Co content in liver0.50.61.0-0.9-0.9-0.1-0.9-0.3-0.2-0.9-0.9-0.9-0.9-1.0-0.8-0.9-0.70.3-0.7-0.3-0.8-0.8
Cu content in liver0.50.62.20.90.80.90.81.51.40.60.30.40.40.2-0.1-0.2-0.31.2-0.6-1.2-0.6-0.6
Fe content in liver0.70.92.70.60.71.60.71.51.50.40.00.00.30.0-0.6-0.5-0.91.3-1.1-1.3-0.9-0.9
K content in liver7.16.814.33.83.60.93.62.72.43.53.33.33.13.12.72.41.90.91.4-0.91.31.2
Mg content in liver5.45.511.83.43.31.53.32.82.63.22.82.82.82.72.01.91.01.20.8-1.20.80.8
Mn content in liver4.55.08.12.52.5-0.82.50.60.32.72.82.82.82.82.72.72.0-1.02.31.02.32.3
Na content in liver2.62.78.52.11.92.11.92.92.71.61.11.21.21.00.40.2-0.22.2-0.7-2.2-0.8-0.9
Rb content in liver1.82.14.22.02.01.42.02.12.01.81.41.51.71.40.80.70.01.2-0.1-1.20.10.0
Se content in liver2.42.96.52.62.31.32.32.52.42.11.81.81.51.61.21.00.71.60.0-1.6-0.1-0.1
Sr content in liver0.70.61.2-0.9-1.0-0.1-1.0-0.3-0.3-1.0-1.0-1.0-1.1-1.0-0.9-0.9-0.70.3-0.7-0.3-0.8-0.8
Zn content in liver0.40.41.01.00.7-0.20.70.50.50.70.90.90.40.61.00.70.90.30.5-0.30.30.3
Bone: minimum diameter1.32.46.3-0.7-0.8-2.5-0.8-2.3-2.2-0.20.30.3-0.10.31.21.21.8-2.31.92.31.71.8
Time in familiar zone, hab. session 11.01.01.5-0.8-0.90.8-0.90.30.3-1.0-1.1-1.1-1.1-1.1-1.2-1.2-1.00.9-1.2-0.9-1.2-1.2
Time in novel zone, hab. session 10.50.51.10.10.4-0.90.4-0.7-0.70.40.50.50.80.60.60.70.6-1.00.91.11.00.9
Total zone transitions, hab. session 12.53.55.92.42.4-0.62.41.00.92.42.42.42.22.42.22.11.8-0.31.60.31.51.6
Total locomotion distance, hab. session 11.72.45.32.32.31.12.32.01.92.11.81.81.81.71.11.10.41.00.3-1.00.30.4
Locomotion velocity, hab. session 12.43.47.02.62.60.32.61.71.62.42.32.42.12.32.01.81.20.51.1-0.51.01.1
Time in familiar zone, hab. session 21.81.94.1-0.5-0.62.0-0.61.11.2-0.8-1.2-1.2-0.8-1.2-1.7-1.6-1.91.6-1.9-1.5-1.7-1.7
Time in novel zone, hab. session 21.91.95.5-0.2-0.0-2.3-0.0-1.8-1.90.20.70.70.40.71.31.31.7-2.01.82.01.61.6
Total zone transitions, hab. session 24.76.19.83.03.0-0.83.00.90.93.13.13.13.03.12.92.92.4-0.72.20.72.32.2
Total locomotion distance, hab. session 23.24.17.02.52.5-0.32.50.90.82.62.62.62.72.62.42.31.8-0.41.70.41.81.8
Locomotion velocity, hab. session 24.05.48.82.92.8-0.52.81.00.92.93.03.03.02.92.82.72.1-0.52.00.52.12.0
Novel to familiar place preference ratio0.70.82.5-0.0-0.1-1.6-0.1-1.1-1.00.20.50.50.60.40.90.91.2-1.11.11.10.91.0
Novelty place preference1.41.54.9-0.3-0.4-2.2-0.4-1.7-1.70.00.40.40.50.41.11.11.5-1.71.51.71.31.4
Time in novel zone, NPP test1.01.13.8-0.5-0.6-1.9-0.6-1.6-1.6-0.20.20.20.30.10.80.81.2-1.61.21.51.01.1
Total zone transitions, NPP test1.52.13.61.91.8-0.51.80.60.61.81.91.91.61.81.91.71.4-0.31.30.31.31.2
Total locomotion distance, NPP test1.92.64.52.12.0-0.32.00.70.72.12.12.11.92.12.01.91.4-0.31.40.31.41.4
Locomotion velocity, NPP test1.52.13.71.91.8-0.21.80.80.81.81.91.91.71.81.81.71.3-0.11.10.11.11.1
Intraocular pressure1.11.52.9-1.7-1.6-0.2-1.6-0.8-0.7-1.6-1.6-1.6-1.5-1.6-1.5-1.4-0.90.0-0.8-0.0-1.0-0.9
Delta distance traveled before/after self-admin0.10.10.70.10.00.80.00.30.30.0-0.1-0.10.3-0.1-0.3-0.2-0.60.3-0.5-0.3-0.4-0.3
Delta ambulatory time before/after self-admin0.20.31.70.30.41.30.40.60.80.20.00.00.40.0-0.4-0.3-0.80.6-0.6-0.6-0.5-0.4
Parametrial fat weight4.610.917.3-2.9-3.01.9-3.00.70.8-3.4-3.8-3.8-3.5-3.9-4.2-4.1-4.12.6-3.9-2.6-3.9-3.5
Pavlov. Cond. lever latency0.60.72.3-0.7-0.41.1-0.40.20.3-0.6-0.9-0.9-0.4-0.7-1.3-1.1-1.50.6-1.2-0.5-0.9-0.9
Pavlov. Cond. magazine entry latency1.21.63.71.91.60.51.61.41.61.61.51.51.21.31.31.11.10.80.4-0.90.20.2
Pavlov. Cond. change in total contacts0.80.81.50.90.8-0.70.8-0.1-0.01.01.11.11.01.01.21.11.2-0.61.10.61.01.1
Pavlov. Cond. index score1.11.42.81.61.3-0.41.30.70.81.41.51.51.11.31.61.41.70.11.1-0.10.80.8
Pavlov. Cond. latency score1.11.42.91.51.2-0.51.20.50.61.41.51.51.11.31.61.41.7-0.11.20.00.90.9
Pavlov. Cond. lever contacts0.20.21.20.50.1-0.70.10.0-0.00.30.50.50.10.30.80.61.1-0.10.60.10.30.3
Pavlov. Cond. magazine entry number1.41.83.8-2.0-1.7-0.0-1.7-1.0-1.2-1.7-1.8-1.8-1.4-1.5-1.6-1.4-1.5-0.4-0.90.4-0.7-0.7
Pavlov. Cond. intertrial magazine entries1.51.83.2-1.6-1.50.6-1.5-0.3-0.4-1.5-1.7-1.7-1.6-1.6-1.8-1.6-1.80.4-1.4-0.4-1.3-1.2
Pavlov. Cond. lever-magazine prob. diff.1.01.22.51.61.2-0.21.20.80.81.31.41.41.01.21.51.21.50.20.9-0.20.70.7
Pavlov. Cond. response bias1.01.32.51.61.3-0.31.30.70.81.41.51.51.11.31.51.31.60.11.0-0.20.70.7
Pavlov. Cond. lever latency0.91.24.31.21.02.11.01.71.90.70.40.40.10.3-0.1-0.2-0.71.6-0.9-1.6-0.9-0.7
Pavlov. Cond. magazine entry latency0.00.00.20.10.1-0.30.1-0.0-0.10.20.20.20.40.20.20.20.4-0.10.30.10.20.0
Pavlov. Cond. change in total contacts1.11.85.5-1.8-1.6-2.3-1.6-1.9-2.3-1.3-1.0-1.0-0.8-0.8-0.3-0.20.6-1.60.81.60.60.5
Pavlov. Cond. index score0.81.13.7-1.2-1.2-1.9-1.2-1.5-1.8-0.8-0.6-0.6-0.4-0.5-0.1-0.00.7-1.30.71.30.60.4
Pavlov. Cond. latency score0.81.14.2-1.0-1.0-2.1-1.0-1.5-1.8-0.6-0.4-0.4-0.2-0.30.20.21.0-1.40.91.40.80.6
Pavlov. Cond. lever contacts0.71.03.2-1.3-1.1-1.8-1.1-1.5-1.7-0.8-0.6-0.6-0.2-0.4-0.1-0.00.5-1.40.61.40.60.5
Pavlov. Cond. magazine entry number0.60.72.60.50.41.60.41.21.30.1-0.1-0.1-0.3-0.2-0.5-0.5-1.01.3-1.0-1.3-1.0-0.7
Pavlov. Cond. intertrial magazine entries0.20.30.70.60.80.40.80.70.80.60.50.50.50.50.10.2-0.50.4-0.2-0.3-0.00.1
Pavlov. Cond. lever-magazine prob. diff.0.91.13.5-1.3-1.2-1.8-1.2-1.6-1.9-0.9-0.6-0.6-0.4-0.5-0.1-0.00.6-1.40.71.40.60.4
Pavlov. Cond. response bias0.50.72.4-1.1-0.9-1.6-0.9-1.3-1.5-0.7-0.5-0.5-0.1-0.4-0.2-0.10.3-1.20.51.20.50.4
Time in closed arm before self-admin1.01.23.91.61.51.01.41.62.01.11.01.00.70.80.70.50.51.3-0.1-1.3-0.4-0.2
Time in closed arm after self-admin0.50.61.61.00.80.50.81.31.20.70.60.60.30.30.40.20.51.1-0.2-1.1-0.6-0.2
Time in open arm before self-admin0.40.41.1-0.0-0.2-1.1-0.1-0.6-0.90.00.30.30.30.20.60.60.9-0.80.80.70.61.0
Time in open arm after self-admin0.30.40.70.60.8-0.70.80.20.20.90.70.80.80.80.60.70.2-0.30.50.20.60.4
Bone: periosteal estimation2.85.911.80.10.1-3.20.1-2.9-2.60.71.51.51.01.62.62.63.1-3.43.33.43.23.3
Bone: periosteal perimeter2.13.68.2-0.4-0.5-2.9-0.5-2.6-2.50.10.80.70.30.71.81.72.4-2.82.52.72.32.4
Bone: post-yield work0.81.12.70.10.3-1.20.3-0.9-1.20.50.70.70.90.91.01.11.0-1.51.51.51.61.4
Progressive ratio test 1 active lever presses1.11.45.9-1.3-1.3-2.4-1.3-1.8-2.0-0.9-0.5-0.5-0.7-0.50.20.20.8-1.50.91.50.70.6
Progressive ratio test 1 breakpoint1.31.56.3-1.3-1.3-2.5-1.3-1.9-2.1-0.9-0.5-0.4-0.6-0.40.30.30.9-1.61.01.60.80.7
Progressive ratio test 1 inactive lever presses1.01.44.8-1.4-1.4-2.2-1.2-1.9-2.0-1.1-0.7-0.7-1.0-0.70.1-0.00.8-1.40.71.30.50.4
Progressive ratio test 2 active lever presses0.20.21.70.20.1-1.30.2-0.00.00.20.40.4-0.00.20.60.50.8-0.20.50.20.3-0.2
Progressive ratio test 2 breakpoint0.10.21.60.10.0-1.30.10.00.00.10.30.3-0.10.20.50.40.7-0.10.40.10.2-0.3
Progressive ratio test 2 inactive lever presses0.40.74.3-0.9-0.9-2.1-0.8-1.1-1.2-0.5-0.3-0.3-0.5-0.30.20.20.5-1.10.51.00.4-0.2
Incentive Sensitization - Responses1.42.05.62.01.80.72.02.32.41.51.31.31.01.00.80.50.61.6-0.2-1.7-0.3-0.9
Incentive Sensitization - Breakpoint1.31.75.21.71.60.71.72.22.31.31.11.10.80.80.60.40.41.6-0.3-1.7-0.4-1.0
Sum of active levers in priming session hrs 5-61.81.63.5-1.8-1.7-0.8-1.7-1.2-1.2-1.7-1.5-1.5-1.9-1.5-1.2-1.1-1.0-0.3-0.50.3-0.90.1
Progressive ratio1.32.05.71.72.11.02.10.80.82.01.71.72.41.90.91.3-0.1-0.30.60.41.21.0
Food seeking constrained by brief footshock0.60.71.70.80.9-0.21.0-0.1-0.11.01.01.01.31.10.81.00.5-0.70.80.71.10.7
Seeking ratio, punishment vs. effort0.40.61.4-1.0-1.2-0.9-1.1-0.6-0.6-1.0-0.9-0.9-1.2-1.0-0.5-0.60.0-0.0-0.2-0.0-0.5-0.5
Retroperitoneal fat weight2.711.519.6-1.9-2.23.6-2.21.92.1-2.6-3.4-3.4-2.7-3.5-4.2-4.2-4.33.7-4.4-3.6-4.4-4.0
Reaction time number correct0.30.51.0-0.5-0.60.0-0.60.40.4-0.6-0.8-0.8-0.6-0.9-0.8-0.9-0.70.8-0.8-0.8-1.0-0.9
Reaction time mean minus median2.66.313.73.63.70.93.62.52.43.43.13.23.13.02.42.31.70.91.1-0.91.11.0
Reaction time mean minus median AUC1.74.39.82.93.10.43.02.11.92.82.52.62.72.41.91.81.30.70.9-0.70.90.7
Reaction time num false alarms0.40.51.60.00.2-0.80.2-0.5-0.60.40.40.40.90.50.50.70.4-1.00.91.01.11.3
Reaction time num false alarms AUC0.40.72.20.20.4-0.80.4-0.5-0.60.60.60.61.10.70.70.90.4-1.11.01.11.31.5
Reaction time trials correct on left0.30.51.0-0.5-0.60.0-0.60.40.4-0.6-0.8-0.8-0.6-0.9-0.8-0.9-0.70.8-0.8-0.8-1.0-0.9
Reaction time trials on left0.20.40.8-0.4-0.50.0-0.50.40.4-0.5-0.7-0.6-0.4-0.8-0.7-0.8-0.60.7-0.7-0.7-0.9-0.8
Reaction time mean0.71.13.41.31.31.11.31.81.71.20.70.81.30.70.10.1-0.31.2-0.5-1.2-0.4-0.3
Reaction time mean AUC0.71.23.91.21.31.21.22.01.81.10.60.61.10.5-0.1-0.1-0.51.4-0.7-1.4-0.6-0.6
Median of all reaction times0.40.61.70.30.31.00.31.31.10.2-0.2-0.20.4-0.2-0.7-0.6-1.01.1-0.9-1.1-0.8-0.7
Reaction time omissions3.24.611.32.62.7-0.12.71.10.92.92.72.73.42.72.22.41.3-0.61.60.71.91.8
Reaction time false alarm rate0.70.92.50.10.3-0.80.3-0.9-0.90.50.60.61.00.80.81.00.6-1.41.21.41.51.6
Reaction time premature initiation rate0.50.72.6-0.6-0.6-1.6-0.5-1.2-1.3-0.4-0.0-0.0-0.4-0.00.50.41.2-1.11.01.10.80.8
Reaction time premature initiations0.30.52.5-0.7-0.8-1.6-0.7-0.8-1.0-0.6-0.3-0.3-0.6-0.40.10.00.8-0.60.60.60.30.4
Std. dev. reaction times2.34.28.82.93.00.92.82.11.92.82.52.52.92.41.81.81.10.70.8-0.70.90.8
Reaction time trials completed0.20.40.8-0.4-0.50.0-0.50.40.4-0.5-0.7-0.6-0.4-0.8-0.7-0.8-0.60.7-0.7-0.7-0.9-0.8
Reaction time trials AUC0.30.61.1-0.7-0.80.1-0.70.30.3-0.7-0.9-0.9-0.7-1.0-0.9-1.0-0.80.8-0.9-0.8-1.0-0.9
Run reversals in cocaine runway, females2.02.03.71.61.71.21.70.50.51.71.71.61.91.91.21.40.7-0.51.10.61.51.9
Run reversals in cocaine runway, males0.10.10.90.0-0.1-1.0-0.10.10.1-0.20.00.0-0.3-0.20.30.10.60.20.2-0.3-0.20.2
Latency to leave start box in cocaine runway0.20.21.20.30.41.10.40.70.70.20.00.00.10.0-0.3-0.3-0.40.6-0.5-0.6-0.3-0.2
Latency to leave start box in cocaine runway, F0.40.42.50.50.81.60.80.80.90.50.20.20.70.3-0.3-0.2-0.50.6-0.5-0.6-0.2-0.0
Latency to leave start box in cocaine runway, M0.40.41.0-0.3-0.50.3-0.50.30.3-0.5-0.6-0.6-0.9-0.7-0.6-0.7-0.40.7-0.7-0.7-0.7-1.0
Std. dev. time between licks in bursts0.20.20.80.50.50.00.50.90.90.40.20.30.00.20.1-0.0-0.10.7-0.3-0.8-0.4-0.4
Total sessions with >9 infusions0.50.61.7-1.1-1.3-0.9-1.0-0.7-0.8-1.1-0.9-0.9-1.2-0.9-0.6-0.6-0.2-0.3-0.20.3-0.3-0.5
Short access day 1 total inactive lever presses5.57.213.8-3.4-3.3-1.0-3.3-1.1-1.3-3.5-3.4-3.4-3.7-3.4-3.0-3.0-2.10.6-2.1-0.6-2.4-2.4
Short access day 10 total inactive lever presses0.10.31.2-0.6-0.7-1.1-0.7-0.8-0.9-0.5-0.3-0.3-0.6-0.40.10.00.5-0.60.30.60.00.2
Short access day 1 total infusions2.33.16.1-2.4-2.4-1.1-2.4-1.3-1.2-2.3-2.2-2.2-2.5-2.1-1.8-1.7-1.3-0.1-1.00.1-1.3-1.0
Short access day 10 total infusions0.20.20.8-0.6-0.9-0.4-0.8-0.3-0.6-0.5-0.5-0.5-0.5-0.6-0.2-0.30.4-0.2-0.00.2-0.2-0.4
Short access total infusions0.91.22.8-1.3-1.5-0.8-1.4-0.4-0.4-1.4-1.3-1.3-1.7-1.3-1.0-1.1-0.50.3-0.7-0.3-1.1-1.2
Short access day 1 locomotion0.81.01.9-1.2-1.3-0.2-1.4-0.3-0.5-1.2-1.2-1.2-1.3-1.2-1.1-1.0-0.90.2-0.9-0.2-0.8-1.0
Short access day 10 total locomotion0.10.20.3-0.4-0.50.3-0.40.1-0.3-0.4-0.5-0.6-0.6-0.6-0.3-0.50.20.2-0.2-0.2-0.3-0.3
Short access total locomotion0.40.51.2-0.8-1.1-0.3-1.0-0.3-0.6-0.9-0.8-0.8-1.0-0.9-0.5-0.60.00.0-0.2-0.1-0.4-0.4
One hour access (0.3 mA shock)1.61.94.5-1.9-1.9-2.1-1.8-2.0-2.1-1.5-1.2-1.2-1.3-1.2-0.4-0.40.3-1.40.31.40.2-0.2
Compulsive drug intake1.72.04.10.81.2-0.51.3-1.0-0.71.31.41.31.71.61.31.60.9-1.71.51.82.02.0
One hour access (shock baseline)0.91.33.0-1.4-1.7-1.1-1.7-0.2-0.7-1.4-1.4-1.3-1.5-1.5-0.9-1.1-0.20.3-0.6-0.3-1.1-1.3
Social response proportion0.30.30.9-0.2-0.1-0.9-0.1-0.7-0.8-0.00.20.20.20.30.40.40.4-0.90.70.90.60.9
Social responses0.40.51.6-0.6-0.6-1.2-0.6-1.3-1.2-0.4-0.1-0.1-0.0-0.00.30.30.4-1.10.71.10.60.5
Social time1.41.94.4-2.1-1.9-1.4-1.9-1.5-1.7-1.8-1.6-1.6-1.4-1.4-1.2-1.0-0.9-0.9-0.20.9-0.4-0.3
Soleus weight0.72.06.1-1.1-1.1-2.0-1.1-2.2-2.5-0.6-0.1-0.2-0.00.00.60.71.2-2.21.52.21.51.4
Bone: stiffness1.42.33.81.41.3-0.61.3-0.3-0.21.51.81.81.61.81.91.91.7-1.21.81.11.91.9
Tibialis anterior weight3.512.024.2-4.9-4.8-0.8-4.8-2.9-2.9-4.6-4.4-4.4-4.2-4.2-3.6-3.5-2.5-0.7-2.10.7-2.1-1.9
Time to tail flick, vehicle, before self-admin0.80.81.20.81.0-0.91.0-0.3-0.01.01.11.10.81.11.11.10.9-0.61.10.61.01.0
Time to tail flick, vehicle, after self-admin1.31.84.60.80.6-1.10.6-0.7-0.90.91.31.21.31.21.71.62.2-1.31.81.31.71.6
Time to tail flick, test, before self-admin1.01.02.1-1.0-1.1-0.0-1.1-0.1-0.0-1.3-1.2-1.1-1.4-1.2-1.0-1.1-0.80.6-1.0-0.6-1.1-1.4
Time to tail flick, test, after self-admin1.01.12.3-1.5-1.3-0.9-1.3-1.3-1.1-1.3-1.1-1.1-1.2-1.0-0.9-0.7-0.9-0.8-0.40.8-0.2-0.8
Delta time to tail flick, vehicle, before/after SA0.70.71.50.50.3-0.40.4-0.4-0.60.60.80.70.90.81.01.01.2-0.91.10.91.21.0
Delta time to tail flick, test, before/after SA0.20.20.70.20.4-0.00.4-0.3-0.20.60.40.40.70.60.30.50.0-0.70.40.80.80.2
Tibia length0.72.07.2-1.4-1.6-1.4-1.6-2.7-2.6-1.1-0.5-0.6-0.8-0.50.30.40.8-2.11.12.11.10.9
Ambulatory time before self-admin0.20.30.90.20.2-0.80.1-0.4-0.60.30.40.40.30.40.70.61.0-0.60.60.60.60.0
Ambulatory time after self-admin0.30.31.2-0.1-0.01.1-0.00.40.5-0.2-0.4-0.4-0.2-0.4-0.6-0.6-0.70.6-0.9-0.6-0.8-0.9
Bone: tissue strength0.30.30.6-0.1-0.10.7-0.10.70.6-0.2-0.4-0.4-0.3-0.4-0.6-0.6-0.60.7-0.7-0.7-0.7-0.7
Total heroin consumption1.82.14.5-2.1-2.0-1.1-2.0-1.9-1.8-1.9-1.6-1.6-1.7-1.5-1.1-1.0-0.7-1.0-0.21.0-0.30.2
Bone: trabecular number2.64.37.6-2.7-2.7-0.2-2.7-1.1-1.3-2.7-2.7-2.7-2.7-2.6-2.3-2.3-1.90.2-1.6-0.2-1.7-1.5
Bone: trabecular spacing2.63.58.82.62.42.42.43.02.92.01.61.61.71.40.70.6-0.02.1-0.6-2.1-0.5-0.5
Bone: trabecular thickness1.21.53.3-1.8-1.7-0.6-1.7-1.6-1.4-1.6-1.4-1.4-1.3-1.3-1.1-0.9-0.9-0.9-0.30.9-0.2-0.1
Bone: trabecular tissue density2.23.35.92.32.20.02.21.00.92.42.32.32.42.32.12.01.6-0.41.60.41.61.6
Water consumed over 24 hours1.21.62.8-1.5-1.60.5-1.6-0.5-0.4-1.6-1.6-1.6-1.7-1.6-1.4-1.5-1.20.4-1.1-0.4-1.2-1.2
Number of responses in last shaping day0.70.82.0-1.1-1.4-0.3-1.4-0.0-0.7-1.0-1.2-1.2-1.0-1.3-0.9-1.0-0.40.3-0.5-0.3-0.8-0.4