Hub : Genes

Cmtr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Cmtr1 0.09 0.09 7.1e-07 0.05 0.05 0.05 0.05 1.8e-06 2.6e-06 4.9e-06 3.4e-06
2 Liver mRNA stability Cmtr1 0.09 0.07 1.8e-12 0.11 0.11 0.1 0.12 1.2e-12 3.1e-12 1.4e-11 1.2e-12
3 NAcc mRNA stability Cmtr1 0.12 0.08 4.8e-13 0.11 0.11 0.11 0.12 2.1e-12 1.1e-12 9.2e-13 2.8e-13
4 OFC mRNA stability Cmtr1 0.24 0.17 6.4e-05 0.1 0.12 0.1 0.13 2.1e-03 1.0e-03 2.7e-03 6.3e-04
5 PL mRNA stability Cmtr1 0.12 0.08 1.8e-14 0.12 0.13 0.13 0.14 2.5e-13 1.4e-14 4.6e-14 9.9e-15
6 Brain mRNA stability Cmtr1 0.07 0.06 2.1e-06 0.04 0.04 0.04 0.04 5.9e-05 5.1e-05 5.2e-05 1.4e-04
7 BLA mRNA stability Cmtr1 0.14 0.1 9.6e-08 0.1 0.13 0.11 0.12 3.8e-06 1.9e-07 1.5e-06 6.3e-07
8 BLA gene expression Cmtr1 0.15 0.08 1.3e-10 0.14 0.2 0.18 0.18 3.7e-08 7.0e-11 1.0e-09 9.9e-10
9 NAcc gene expression Cmtr1 0.01 0.01 1.0e-02 0 0 0 0 7.3e-02 3.0e-01 2.9e-01 2.3e-01
10 Adipose mRNA stability Cmtr1 0.06 0.05 1.5e-08 0.06 0.07 0.06 0.06 1.5e-07 6.5e-08 1.2e-07 3.3e-07
11 Brain gene expression Cmtr1 0.03 0.02 1.9e-03 0.02 0.02 0.01 0.01 1.0e-02 5.8e-03 1.3e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.91.51.81.41.21.21.31.31.21.2-1.21.01.1-1.2
Area under the delay curve1.41.52.8-1.1-1.7-1.1-1.1-1.2-1.2-1.11.2-1.1-1.21.2
BMI with tail3.09.810.8-3.3-3.3-3.2-3.2-3.3-3.1-3.03.1-3.0-3.03.0
BMI without tail1.83.74.5-1.9-2.1-1.9-1.9-1.9-2.0-1.91.9-2.0-1.91.9
Body weight7.129.632.4-5.6-5.7-5.4-5.6-5.6-5.3-5.45.4-4.9-5.45.4
Weight adjusted by age3.53.95.8-1.9-1.6-2.3-1.7-1.8-2.2-2.02.1-2.4-1.81.7
Bone surface0.00.00.0-0.0-0.1-0.0-0.00.0-0.10.00.0-0.2-0.00.0
Bone volume0.00.00.00.1-0.1-0.10.10.1-0.00.00.1-0.2-0.10.1
Breakpoint value in progressive ratio session0.40.40.60.60.60.70.60.70.70.6-0.70.80.7-0.7
Number of licking bursts0.50.60.80.80.90.70.80.80.70.8-0.70.60.8-0.8
Context. condit. distance diff. score0.20.30.50.40.40.60.40.40.50.5-0.50.70.5-0.5
Locomotion velocity, session 11.41.53.11.00.81.41.01.01.41.2-1.31.71.2-1.1
Locomotion distance, session 13.54.54.92.22.12.22.22.22.12.1-2.12.02.1-2.1
Locomotion velocity, session 20.20.30.40.70.40.50.60.60.50.5-0.50.40.5-0.5
Locomotion distance, session 20.81.11.31.11.11.01.11.11.01.0-1.00.91.0-1.0
Locomotion velocity, session 30.00.00.1-0.1-0.10.1-0.2-0.20.0-0.20.10.2-0.20.3
Locomotion distance, session 30.60.60.80.80.90.90.70.80.90.7-0.80.90.7-0.7
Stereotopy head waving bouts, day 31.51.72.0-1.3-1.3-1.3-1.4-1.4-1.3-1.41.3-1.0-1.41.4
Stereotopy head waving duration, day 30.30.30.4-0.6-0.6-0.6-0.5-0.5-0.6-0.60.6-0.6-0.60.6
Locomotion velocity, session 70.20.20.50.70.70.20.60.60.20.3-0.2-0.00.2-0.2
Locomotion distance, session 71.11.42.41.41.51.01.41.41.01.1-1.00.71.0-1.0
Stereotopy head waving bouts, day 70.10.10.2-0.3-0.5-0.2-0.4-0.4-0.3-0.40.4-0.1-0.40.5
Stereotopy head waving duration, day 70.70.81.0-0.8-0.9-0.8-0.9-0.9-0.9-0.90.9-0.8-1.01.0
Locomotion velocity, session 80.00.00.10.1-0.00.20.10.10.20.1-0.10.40.1-0.1
Locomotion distance, session 80.71.01.21.11.01.11.11.10.90.9-0.90.91.0-1.0
Degree of sensitization distance0.10.10.5-0.1-0.0-0.5-0.1-0.1-0.4-0.30.4-0.7-0.30.2
Degree of sensitization stereotypy0.20.20.20.50.30.50.40.40.50.4-0.40.50.3-0.3
Conditioned locomotion2.02.42.6-1.6-1.4-1.6-1.6-1.5-1.5-1.61.6-1.4-1.61.6
Cocaine response after cond. corrected1.92.22.7-1.7-1.5-1.5-1.5-1.6-1.5-1.51.4-1.3-1.31.3
Cocaine response after cond. not corrected1.61.82.4-1.5-1.5-1.3-1.4-1.5-1.3-1.31.2-1.1-1.21.2
Cocaine response before conditioning0.10.20.40.50.20.50.40.30.50.4-0.40.60.3-0.3
Saline control response0.40.60.8-0.8-0.9-0.6-0.8-0.9-0.6-0.80.7-0.4-0.80.8
Bone: connectivity density0.71.11.21.10.91.11.11.01.01.1-1.00.91.0-1.0
Bone: cortical apparent density0.10.10.20.40.10.20.40.30.20.3-0.20.20.2-0.2
Bone: cortical area0.81.21.8-1.1-1.4-1.1-1.1-1.1-1.1-1.11.1-1.1-1.01.0
Bone: cortical porosity0.00.00.1-0.3-0.2-0.1-0.2-0.2-0.1-0.10.1-0.1-0.10.1
Bone: cortical porosity0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.3-0.10.1
Bone: cortical thickness0.00.00.10.1-0.30.00.1-0.00.10.1-0.10.00.1-0.1
Bone: cortical thickness0.00.00.0-0.00.1-0.0-0.10.1-0.0-0.10.1-0.0-0.10.1
Bone: cortical tissue density0.00.00.10.30.00.10.30.20.10.2-0.10.10.1-0.1
Condit. Reinf. active minus inactive responses1.21.41.71.11.01.31.01.11.31.2-1.21.31.2-1.2
Condit. Reinf. active-inactive response ratio0.10.10.20.20.10.40.20.20.30.3-0.30.40.3-0.3
Condit. Reinf. active responses0.70.81.30.80.71.00.80.81.00.9-1.01.10.9-0.8
Condit. Reinf. inactive responses0.81.01.21.00.91.00.91.01.11.0-1.01.10.9-0.9
Incentive salience index mean0.50.60.80.70.60.90.70.70.90.8-0.80.90.8-0.8
Condit. Reinf. lever presses0.00.00.00.1-0.00.20.10.10.20.2-0.20.10.2-0.2
Condit. Reinf. active minus inactive responses1.41.73.61.01.01.51.00.91.51.2-1.41.91.3-1.3
Condit. Reinf. active-inactive response ratio0.50.51.40.30.40.80.30.30.80.7-0.81.20.8-0.8
Condit. Reinf. active responses1.31.83.51.11.11.61.11.01.51.3-1.41.91.3-1.2
Condit. Reinf. inactive responses0.00.10.20.20.20.40.20.20.30.1-0.20.40.00.0
Condit. Reinf. lever presses4.76.38.42.32.52.82.32.32.72.4-2.62.92.4-2.4
Condit. Reinf. lever reinforcers received2.23.15.31.51.52.01.51.41.91.7-1.82.31.7-1.6
Conditioned reinforcement - actives0.50.50.8-0.9-0.5-0.6-0.9-0.9-0.6-0.70.6-0.4-0.70.7
Conditioned reinforcement - inactives0.40.40.60.70.80.70.60.50.70.6-0.70.60.6-0.6
Conditioned locomotion0.70.91.1-1.0-0.6-1.0-1.0-1.0-0.9-0.90.9-0.9-0.90.9
Patch foraging indifference point 0 sec0.30.50.8-0.6-0.2-0.8-0.7-0.8-0.8-0.80.8-0.9-0.80.8
Patch foraging indifference point AUC0.10.10.30.20.40.40.20.20.40.3-0.40.50.3-0.3
Delay disc. indifference point, 0s delay1.21.31.9-1.3-1.1-1.2-1.2-1.4-1.2-1.01.1-1.2-0.90.9
Delay disc. indifference point, 16s delay0.10.10.60.0-0.80.3-0.0-0.00.20.0-0.00.5-0.20.2
Delay disc. indifference point, 2s delay0.10.10.3-0.1-0.1-0.4-0.1-0.2-0.4-0.20.3-0.5-0.20.1
Delay disc. indifference point, 24s delay2.62.55.2-1.5-2.3-1.5-1.5-1.5-1.5-1.51.6-1.2-1.71.7
Delay disc. indifference point, 4s delay1.81.92.5-1.3-1.6-1.4-1.3-1.4-1.4-1.41.4-1.2-1.41.4
Delay disc. indifference point, 8s delay1.92.02.7-1.2-1.6-1.4-1.3-1.5-1.4-1.41.4-1.4-1.51.5
Indifference point function ln k0.00.10.10.20.4-0.10.20.3-0.00.2-0.0-0.40.1-0.2
Indifference point function log k0.00.10.10.20.4-0.10.20.3-0.00.2-0.0-0.40.1-0.2
Patch foraging total patch changes 0 sec0.30.50.9-0.6-0.1-0.8-0.7-0.7-0.8-0.80.8-1.0-0.80.7
Patch foraging total patch changes 12 sec0.00.00.3-0.20.50.1-0.2-0.10.1-0.0-0.10.20.1-0.0
Patch foraging total patch changes 18 sec0.30.40.6-0.5-0.4-0.5-0.6-0.5-0.5-0.70.6-0.5-0.80.8
Patch foraging total patch changes 24 sec0.10.20.50.30.70.40.40.30.40.4-0.40.20.5-0.5
Patch foraging total patch changes 6 sec0.00.10.1-0.3-0.0-0.2-0.3-0.4-0.2-0.30.2-0.2-0.30.3
Patch foraging time to switch 0 sec1.11.72.6-1.6-1.6-1.1-1.5-1.4-1.1-1.41.2-0.8-1.31.3
Patch foraging water rate 0 sec0.10.20.70.30.8-0.30.40.3-0.20.20.0-0.70.2-0.2
Patch foraging water rate 12 sec0.10.20.40.60.60.20.60.60.20.4-0.3-0.10.3-0.3
Patch foraging water rate 18 sec0.81.11.51.21.01.01.21.11.01.1-1.00.90.9-1.0
Patch foraging water rate 24 sec0.30.40.80.90.80.50.90.80.40.5-0.50.20.5-0.5
Patch foraging water rate 6 sec0.10.10.30.50.50.00.50.50.10.2-0.1-0.30.2-0.3
Seeking ratio, delayed vs. immediate footshock0.50.50.80.9-0.20.80.70.70.90.8-0.70.80.5-0.5
Distance traveled before self-admin1.01.11.5-1.2-0.7-1.2-1.1-1.1-1.1-1.01.0-1.0-1.00.9
Distance traveled after self-admin0.10.10.2-0.2-0.3-0.4-0.2-0.1-0.3-0.20.3-0.4-0.20.2
Extensor digitorum longus weight0.20.91.20.91.10.90.90.91.00.9-1.01.11.0-0.9
Bone: elastic displacement0.10.10.10.2-0.10.30.20.20.30.3-0.30.40.3-0.3
Bone: elastic work0.10.10.3-0.3-0.5-0.3-0.3-0.3-0.3-0.30.3-0.3-0.30.3
Bone: endosteal estimation3.57.78.2-2.9-2.6-2.7-2.8-2.7-2.8-2.82.8-2.6-2.82.8
Bone: endosteal perimeter2.45.05.9-2.4-2.3-2.2-2.4-2.3-2.2-2.22.2-2.1-2.22.2
Epididymis fat weight1.84.35.4-2.3-2.3-2.0-2.3-2.3-1.9-2.12.0-1.5-2.02.0
Delta time in closed arm before/after self-admin3.13.03.7-1.9-1.6-1.9-1.9-1.9-1.8-1.71.7-1.6-1.61.5
Delta time in open arm before/after self-admin1.01.01.11.11.01.01.00.91.01.0-1.01.00.9-0.9
Diff in mean of infusions in LGA sessions0.80.91.00.91.00.91.01.00.90.9-0.90.81.0-1.0
Delay discount exponential model param1.11.12.30.81.51.00.91.01.01.0-1.11.01.1-1.1
Extinction: sum of active levers before priming0.10.10.5-0.10.50.4-0.10.10.30.1-0.30.70.4-0.4
Active lever presses in extinction session 60.10.00.2-0.2-0.40.2-0.2-0.10.2-0.0-0.10.4-0.00.1
Bone: final force4.97.98.6-2.8-2.9-2.8-2.8-2.7-2.8-2.82.8-2.7-2.82.9
Bone: final moment4.26.87.3-2.6-2.7-2.6-2.6-2.5-2.6-2.62.6-2.5-2.72.7
Food consumed during 24 hour testing period0.70.91.2-1.0-1.1-0.9-1.0-1.0-0.9-0.90.9-0.8-0.90.9
Glucose0.30.50.6-0.7-0.8-0.7-0.6-0.7-0.7-0.60.6-0.7-0.50.5
Heart weight1.41.92.61.21.41.31.41.31.31.5-1.41.01.6-1.6
Delay discount hyperbolic model param0.80.81.70.71.30.90.80.90.90.8-0.90.90.9-0.9
Intermittent access intake day 1-15 change0.00.00.10.1-0.30.0-0.1-0.10.1-0.10.10.2-0.30.3
Intermittent access intake escalation0.10.10.3-0.2-0.6-0.1-0.4-0.4-0.1-0.30.30.1-0.50.5
Intermittent access intake escalation 20.80.81.70.90.81.00.80.81.00.8-0.91.30.8-0.7
Intermitt. access day 1 inactive lever presses0.10.10.3-0.50.3-0.4-0.4-0.5-0.4-0.30.3-0.4-0.10.1
Intermitt. access day 15 inactive lever presses0.30.30.7-0.5-0.8-0.3-0.7-0.7-0.3-0.60.5-0.0-0.60.7
Intermitt. access escalation Index0.30.30.40.60.20.50.60.70.50.6-0.50.40.5-0.6
Intermittent access day 1 total infusions0.40.40.50.70.50.60.60.70.70.6-0.70.50.6-0.6
Intermittent access day 15 total infusions0.00.00.10.2-0.00.20.10.10.20.1-0.10.20.1-0.0
Intermittent access terminal intake (last 3 days)0.10.10.2-0.3-0.2-0.3-0.4-0.3-0.3-0.30.3-0.2-0.30.3
Intermittent access total infusions0.10.10.20.50.40.30.30.40.40.4-0.40.20.3-0.3
Intermittent access day 1 locomotion0.20.20.3-0.4-0.3-0.5-0.5-0.5-0.4-0.40.4-0.5-0.40.4
Intermittent access day 15 total locomotion2.12.33.2-1.5-1.8-1.3-1.7-1.7-1.3-1.51.4-1.0-1.61.7
Intermittent access total locomotion0.60.61.0-0.7-1.0-0.7-0.9-0.9-0.6-0.80.8-0.4-0.90.9
Intermittent access standard deviation0.80.91.2-1.0-0.6-1.0-1.1-1.1-0.9-1.00.9-0.8-0.90.9
Left kidney weight2.98.19.5-3.1-2.9-2.9-3.0-2.9-2.7-2.82.8-2.5-2.82.8
Right kidney weight3.59.810.7-3.3-3.2-3.1-3.3-3.2-3.0-3.13.1-2.9-3.23.2
Cocaine induced anxiety0.30.40.60.80.50.70.70.70.70.6-0.60.60.5-0.5
Post-drug Anxiety0.60.71.00.80.61.00.80.80.90.9-0.91.00.9-0.8
Baseline Anxiety0.00.00.1-0.30.1-0.1-0.1-0.1-0.2-0.10.0-0.10.1-0.1
Tail length0.92.83.1-1.6-1.6-1.7-1.7-1.6-1.7-1.71.7-1.7-1.71.7
Length with tail1.96.97.7-2.7-2.7-2.6-2.8-2.6-2.6-2.72.6-2.2-2.72.7
Length without tail1.63.44.2-2.0-2.0-1.8-2.0-2.0-1.7-1.81.8-1.3-1.81.9
Times rat made contact with spout4.35.05.72.22.42.32.22.22.32.2-2.22.22.1-2.1
Lifetime Intake0.00.00.1-0.1-0.0-0.2-0.2-0.2-0.2-0.20.2-0.3-0.10.2
Liver weight, left3.35.36.7-2.1-2.1-2.2-2.2-2.2-2.3-2.42.4-2.1-2.62.6
Liver weight, right2.13.65.0-1.7-1.3-2.0-1.7-1.6-2.0-1.92.0-2.2-2.02.0
Locomotor activity0.10.20.3-0.2-0.2-0.4-0.1-0.1-0.5-0.40.5-0.6-0.50.5
Locomotor testing distance0.10.20.6-0.2-0.2-0.6-0.1-0.2-0.6-0.40.5-0.7-0.40.4
Locomotor testing rearing1.21.82.2-1.3-1.3-1.5-1.2-1.2-1.4-1.41.4-1.5-1.41.4
Locomotion in novel chamber0.10.10.20.40.1-0.10.40.3-0.10.2-0.1-0.40.2-0.3
Locomotion in novel chamber post-restriction1.92.32.6-1.4-1.5-1.5-1.4-1.4-1.6-1.51.6-1.6-1.61.6
Fecal boli incidents, locomotor time 10.00.00.10.1-0.1-0.10.10.1-0.1-0.00.1-0.3-0.10.1
Change in fecal boli incidents, locomotor task2.52.43.5-1.8-0.8-1.8-1.5-1.5-1.8-1.61.5-1.9-1.21.2
Time >=10cm from walls, locomotor time 12.82.84.1-1.6-1.5-1.7-1.6-1.4-1.8-1.71.7-2.0-1.61.6
Bouts of movement, locomotor time 10.50.50.70.60.70.70.60.60.80.7-0.70.80.7-0.7
Total resting periods, locomotor time 10.30.30.50.40.50.60.40.50.60.5-0.60.70.5-0.4
Rest time, locomotor task time 10.20.30.6-0.8-0.2-0.6-0.6-0.6-0.5-0.50.5-0.4-0.40.4
Distance moved, locomotor task time 10.00.00.2-0.1-0.40.1-0.3-0.3-0.0-0.10.10.1-0.10.2
Vertical activity count, locomotor time 10.40.40.8-0.6-0.9-0.5-0.7-0.7-0.6-0.60.6-0.4-0.70.7
Time >=10cm from walls, locomotor time 211.412.015.5-3.4-2.9-3.7-3.3-3.2-3.7-3.53.6-3.9-3.33.3
Bouts of movement, locomotor time 20.10.10.40.4-0.10.50.30.30.30.1-0.20.70.00.0
Total resting periods, locomotor time 20.30.30.70.60.30.70.60.50.50.4-0.40.90.4-0.3
Rest time, locomotor task time 20.10.10.2-0.5-0.1-0.4-0.4-0.5-0.2-0.20.2-0.0-0.20.1
Distance moved, locomotor task time 21.72.02.3-1.3-1.4-1.3-1.4-1.4-1.4-1.51.4-1.5-1.51.5
Vertical activity count, locomotor time 21.01.11.4-0.9-1.0-1.1-0.9-0.8-1.2-1.21.2-1.1-1.11.1
Light reinforcement 12.24.04.3-2.0-1.8-2.0-2.0-1.9-2.1-2.12.1-2.0-2.02.0
Light reinforcement 22.43.33.6-1.7-1.9-1.8-1.7-1.7-1.8-1.81.9-1.7-1.91.9
Bone: marrow area3.67.98.4-2.9-2.7-2.7-2.9-2.7-2.8-2.92.8-2.7-2.92.9
Bone: maximum diameter0.91.72.2-1.4-1.5-1.2-1.3-1.3-1.3-1.21.3-1.3-1.21.2
Bone: maximum force1.93.33.5-1.8-1.9-1.7-1.8-1.7-1.8-1.81.8-1.8-1.91.9
Bone: maximum moment1.42.52.7-1.6-1.6-1.5-1.6-1.5-1.6-1.61.6-1.5-1.61.7
Mean time between licks in bursts0.50.80.90.90.70.90.90.90.90.9-0.90.80.9-0.9
Mean num. licks in bursts0.50.50.80.70.70.80.70.70.80.7-0.70.90.6-0.6
Cd content in liver0.60.60.8-0.7-0.8-0.8-0.8-0.7-0.8-0.80.8-0.8-0.90.9
Co content in liver2.53.03.2-1.8-1.6-1.8-1.8-1.8-1.7-1.81.7-1.6-1.71.7
Cu content in liver2.83.44.52.02.11.72.02.01.71.9-1.81.41.9-1.9
Fe content in liver3.23.84.3-1.9-2.0-1.9-1.9-1.9-1.9-2.02.0-1.8-2.12.1
K content in liver0.80.81.30.81.10.90.90.80.80.9-0.90.81.0-1.0
Mg content in liver1.41.52.01.11.41.11.21.11.11.2-1.21.01.4-1.4
Mn content in liver0.00.00.00.00.20.00.10.0-0.00.1-0.1-0.10.1-0.2
Na content in liver0.20.30.40.40.70.50.40.40.50.5-0.50.50.6-0.6
Rb content in liver0.30.30.4-0.6-0.4-0.6-0.6-0.6-0.6-0.50.5-0.5-0.50.5
Se content in liver2.12.63.11.61.71.61.61.61.51.7-1.61.41.7-1.8
Sr content in liver0.00.00.00.00.00.00.10.1-0.00.0-0.0-0.00.1-0.1
Zn content in liver3.33.74.8-1.9-1.7-2.0-1.8-1.8-2.1-1.92.0-2.2-1.81.8
Bone: minimum diameter2.44.65.2-2.3-2.3-2.1-2.2-2.2-2.1-2.12.1-2.1-2.02.0
Time in familiar zone, hab. session 10.10.10.50.1-0.00.40.10.10.50.3-0.40.70.3-0.3
Time in novel zone, hab. session 10.70.71.3-0.6-0.6-0.9-0.6-0.6-1.0-0.80.9-1.1-0.80.8
Total zone transitions, hab. session 13.24.54.92.12.22.12.12.12.12.1-2.12.12.1-2.1
Total locomotion distance, hab. session 12.13.13.51.71.71.81.71.71.81.7-1.81.91.8-1.7
Locomotion velocity, hab. session 11.92.73.11.61.61.71.61.61.61.6-1.71.81.7-1.7
Time in familiar zone, hab. session 21.11.11.71.31.10.91.31.30.91.0-1.00.71.0-1.0
Time in novel zone, hab. session 20.80.81.2-1.1-0.9-0.7-1.1-1.1-0.7-1.00.8-0.4-0.91.0
Total zone transitions, hab. session 20.30.40.80.80.90.50.70.70.40.5-0.50.30.5-0.6
Total locomotion distance, hab. session 22.22.93.71.91.91.71.91.91.51.6-1.61.41.6-1.6
Locomotion velocity, hab. session 22.63.54.62.12.11.82.12.11.71.8-1.71.51.8-1.8
Novel to familiar place preference ratio0.60.61.0-1.0-0.8-0.8-0.9-1.0-0.8-0.80.7-0.6-0.70.7
Novelty place preference0.50.50.8-0.9-0.7-0.6-0.8-0.8-0.6-0.70.6-0.5-0.60.6
Time in novel zone, NPP test0.40.50.8-0.9-0.7-0.6-0.9-0.9-0.6-0.70.6-0.3-0.60.6
Total zone transitions, NPP test1.21.72.61.41.61.21.41.41.11.2-1.21.01.3-1.3
Total locomotion distance, NPP test0.91.22.01.21.41.01.21.20.91.0-1.00.81.1-1.1
Locomotion velocity, NPP test1.31.83.01.51.71.11.61.61.11.3-1.20.81.3-1.4
Intraocular pressure0.81.11.5-1.1-1.2-0.9-1.2-1.2-0.9-1.01.0-0.6-1.21.2
Delta distance traveled before/after self-admin0.60.60.90.90.60.80.80.90.80.8-0.80.70.8-0.8
Delta ambulatory time before/after self-admin1.01.11.61.20.81.11.11.21.01.0-1.00.91.0-1.0
Parametrial fat weight0.71.42.0-1.3-1.3-0.9-1.4-1.3-0.9-1.21.1-0.7-1.41.4
Pavlov. Cond. lever latency0.20.20.3-0.5-0.5-0.3-0.6-0.5-0.4-0.50.4-0.2-0.50.5
Pavlov. Cond. magazine entry latency0.20.30.50.50.70.60.60.60.50.6-0.50.50.5-0.5
Pavlov. Cond. change in total contacts0.30.30.6-0.7-0.7-0.4-0.7-0.7-0.4-0.50.4-0.2-0.50.6
Pavlov. Cond. index score0.00.00.00.10.20.10.20.20.10.1-0.1-0.00.1-0.1
Pavlov. Cond. latency score0.00.00.1-0.00.0-0.10.00.0-0.1-0.00.1-0.3-0.10.0
Pavlov. Cond. lever contacts0.10.10.20.40.30.30.40.40.30.4-0.30.20.4-0.4
Pavlov. Cond. magazine entry number0.60.70.8-0.8-0.8-0.9-0.8-0.8-0.8-0.90.9-0.8-0.90.9
Pavlov. Cond. intertrial magazine entries0.20.30.60.40.40.60.30.30.60.5-0.60.80.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.10.10.10.10.10.10.1-0.1-0.00.1-0.1
Pavlov. Cond. response bias0.91.11.40.91.01.21.01.01.11.1-1.11.21.1-1.1
Pavlov. Cond. lever latency2.93.94.8-2.0-2.0-2.1-2.0-2.0-2.1-1.92.0-2.2-1.81.8
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.30.1-0.1-0.20.1-0.1-0.00.3-0.10.2
Pavlov. Cond. change in total contacts2.12.94.01.71.81.81.61.61.81.6-1.72.01.6-1.6
Pavlov. Cond. index score1.21.52.51.21.21.41.11.11.41.1-1.21.61.1-1.0
Pavlov. Cond. latency score0.81.01.70.90.91.10.90.81.10.9-1.01.30.9-0.8
Pavlov. Cond. lever contacts2.63.64.71.92.02.01.81.82.01.8-1.92.21.7-1.6
Pavlov. Cond. magazine entry number0.00.00.1-0.2-0.1-0.2-0.1-0.1-0.2-0.10.1-0.3-0.00.0
Pavlov. Cond. intertrial magazine entries0.50.71.20.91.10.80.91.00.70.8-0.70.60.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.81.01.81.00.91.10.90.91.10.9-1.01.30.8-0.8
Pavlov. Cond. response bias1.92.63.81.61.61.81.61.51.71.5-1.61.91.4-1.3
Time in closed arm before self-admin0.10.10.40.20.60.00.30.5-0.10.2-0.1-0.50.3-0.3
Time in closed arm after self-admin0.50.50.8-0.9-0.5-0.7-0.8-0.7-0.7-0.70.7-0.7-0.60.6
Time in open arm before self-admin1.21.31.71.30.81.21.21.21.31.2-1.21.21.0-1.0
Time in open arm after self-admin3.53.95.12.21.82.02.22.02.02.0-1.91.81.8-1.8
Bone: periosteal estimation2.85.86.3-2.5-2.5-2.3-2.5-2.4-2.4-2.42.4-2.3-2.42.4
Bone: periosteal perimeter1.52.43.0-1.7-1.7-1.5-1.6-1.6-1.5-1.51.5-1.4-1.51.5
Bone: post-yield work0.20.30.4-0.6-0.4-0.4-0.6-0.5-0.5-0.50.5-0.5-0.50.5
Progressive ratio test 1 active lever presses0.00.00.0-0.10.1-0.0-0.1-0.10.0-0.0-0.0-0.00.0-0.0
Progressive ratio test 1 breakpoint0.00.00.1-0.20.1-0.2-0.2-0.2-0.1-0.20.1-0.3-0.00.1
Progressive ratio test 1 inactive lever presses0.50.61.2-0.9-0.8-0.6-1.0-1.1-0.5-0.70.6-0.2-0.70.7
Progressive ratio test 2 active lever presses0.20.20.70.20.40.50.10.10.50.3-0.50.80.4-0.3
Progressive ratio test 2 breakpoint0.20.20.60.40.40.60.30.40.60.4-0.50.70.4-0.3
Progressive ratio test 2 inactive lever presses0.91.11.61.01.11.10.90.91.11.0-1.01.31.0-1.0
Incentive Sensitization - Responses2.12.13.11.31.31.61.31.41.61.4-1.51.81.4-1.3
Incentive Sensitization - Breakpoint1.61.62.61.21.11.41.11.21.41.2-1.31.61.2-1.1
Sum of active levers in priming session hrs 5-60.40.40.60.30.50.70.40.40.70.7-0.70.70.8-0.8
Progressive ratio1.31.52.7-1.0-1.6-1.1-1.1-1.2-1.1-1.31.2-0.8-1.41.5
Food seeking constrained by brief footshock0.00.00.10.3-0.10.10.30.30.10.2-0.10.10.1-0.1
Seeking ratio, punishment vs. effort0.50.61.20.51.10.60.70.80.60.8-0.70.40.9-1.0
Retroperitoneal fat weight1.75.56.8-2.6-2.2-2.3-2.5-2.5-2.3-2.42.3-2.0-2.32.3
Reaction time number correct0.10.20.3-0.4-0.3-0.3-0.6-0.4-0.2-0.40.3-0.0-0.50.5
Reaction time mean minus median0.20.20.70.5-0.00.60.40.40.60.4-0.40.80.2-0.2
Reaction time mean minus median AUC0.10.10.40.3-0.30.40.20.20.40.2-0.30.60.1-0.0
Reaction time num false alarms0.20.30.80.40.90.30.40.40.50.5-0.50.40.5-0.5
Reaction time num false alarms AUC0.60.81.90.81.40.70.80.80.80.9-0.90.71.0-1.0
Reaction time trials correct on left0.10.20.3-0.4-0.3-0.3-0.6-0.4-0.2-0.40.3-0.0-0.50.5
Reaction time trials on left0.10.10.3-0.4-0.3-0.3-0.5-0.4-0.2-0.40.30.0-0.50.5
Reaction time mean0.10.10.2-0.3-0.4-0.1-0.3-0.2-0.2-0.30.20.1-0.40.4
Reaction time mean AUC0.20.20.5-0.5-0.7-0.3-0.5-0.4-0.3-0.50.4-0.0-0.60.6
Median of all reaction times0.20.30.4-0.6-0.6-0.5-0.6-0.5-0.5-0.60.5-0.2-0.60.6
Reaction time omissions0.30.41.00.60.20.80.60.60.80.6-0.61.00.5-0.4
Reaction time false alarm rate0.71.01.81.01.30.81.01.00.81.0-0.90.61.1-1.2
Reaction time premature initiation rate0.10.10.10.10.30.30.20.00.20.3-0.30.40.4-0.4
Reaction time premature initiations0.00.00.1-0.3-0.1-0.0-0.3-0.4-0.0-0.10.00.2-0.00.1
Std. dev. reaction times0.10.20.50.4-0.00.50.40.40.50.3-0.40.70.2-0.2
Reaction time trials completed0.10.10.3-0.4-0.3-0.3-0.5-0.4-0.2-0.40.30.0-0.50.5
Reaction time trials AUC0.10.10.3-0.4-0.3-0.3-0.5-0.4-0.2-0.40.30.0-0.50.5
Run reversals in cocaine runway, females0.00.00.10.0-0.20.20.0-0.10.2-0.0-0.00.3-0.10.2
Run reversals in cocaine runway, males1.00.91.81.30.41.21.11.21.00.9-0.81.20.6-0.6
Latency to leave start box in cocaine runway0.10.10.4-0.70.1-0.1-0.5-0.5-0.2-0.20.00.10.2-0.2
Latency to leave start box in cocaine runway, F0.10.10.3-0.5-0.00.0-0.4-0.3-0.1-0.2-0.00.20.1-0.1
Latency to leave start box in cocaine runway, M0.10.10.3-0.5-0.0-0.3-0.5-0.5-0.3-0.30.3-0.3-0.10.1
Std. dev. time between licks in bursts1.51.82.6-1.6-1.4-1.3-1.5-1.5-1.3-1.31.2-1.2-1.11.1
Total sessions with >9 infusions0.10.10.3-0.5-0.2-0.4-0.5-0.5-0.3-0.40.3-0.3-0.30.3
Short access day 1 total inactive lever presses0.10.10.10.30.30.30.30.30.30.3-0.30.10.4-0.4
Short access day 10 total inactive lever presses0.00.00.10.00.10.1-0.0-0.10.10.0-0.10.40.1-0.0
Short access day 1 total infusions0.50.51.30.61.10.70.70.70.70.7-0.70.30.8-0.8
Short access day 10 total infusions0.00.00.10.10.3-0.10.00.1-0.00.1-0.0-0.30.1-0.1
Short access total infusions0.10.10.3-0.30.0-0.4-0.3-0.3-0.3-0.30.3-0.5-0.20.2
Short access day 1 locomotion0.10.10.3-0.6-0.0-0.3-0.5-0.6-0.3-0.30.2-0.2-0.10.1
Short access day 10 total locomotion0.20.20.7-0.60.8-0.5-0.5-0.5-0.4-0.30.2-0.60.1-0.1
Short access total locomotion0.60.61.0-0.9-0.1-0.9-0.9-0.9-0.9-0.80.7-1.0-0.50.5
One hour access (0.3 mA shock)1.41.62.31.21.31.41.11.11.41.2-1.31.51.3-1.2
Compulsive drug intake0.90.91.60.71.20.70.90.80.81.0-1.00.81.2-1.3
One hour access (shock baseline)0.10.20.50.50.00.50.30.30.50.3-0.40.70.1-0.1
Social response proportion0.70.82.2-0.6-0.4-1.2-0.6-0.7-1.1-0.70.9-1.5-0.70.6
Social responses0.10.10.3-0.5-0.1-0.5-0.4-0.4-0.5-0.30.4-0.5-0.20.2
Social time0.30.40.70.40.70.60.40.50.70.7-0.70.80.7-0.6
Soleus weight0.82.32.7-1.6-1.4-1.6-1.6-1.6-1.6-1.51.5-1.6-1.31.3
Bone: stiffness1.42.22.5-1.5-1.4-1.4-1.5-1.3-1.5-1.51.5-1.5-1.61.6
Tibialis anterior weight0.72.53.41.31.61.61.41.41.61.6-1.61.91.7-1.6
Time to tail flick, vehicle, before self-admin0.60.61.5-0.5-1.2-0.5-0.7-0.7-0.6-0.70.7-0.4-1.01.0
Time to tail flick, vehicle, after self-admin0.00.00.1-0.10.0-0.20.00.2-0.2-0.00.1-0.30.0-0.1
Time to tail flick, test, before self-admin0.20.20.30.40.40.40.40.40.50.5-0.50.40.4-0.4
Time to tail flick, test, after self-admin0.80.81.51.20.51.11.21.20.90.8-0.80.90.6-0.5
Delta time to tail flick, vehicle, before/after SA0.20.20.40.40.70.30.50.60.30.5-0.40.20.6-0.6
Delta time to tail flick, test, before/after SA0.70.61.0-0.4-0.9-0.7-0.5-0.4-0.8-0.90.9-0.8-1.01.0
Tibia length2.16.06.4-2.4-2.5-2.5-2.4-2.4-2.4-2.52.5-2.4-2.52.5
Ambulatory time before self-admin0.40.40.8-0.9-0.4-0.7-0.7-0.7-0.5-0.60.5-0.4-0.60.6
Ambulatory time after self-admin0.30.40.70.70.40.50.60.80.60.6-0.60.50.6-0.6
Bone: tissue strength0.00.00.00.10.2-0.10.10.1-0.1-0.00.1-0.2-0.00.0
Total heroin consumption1.41.61.91.31.31.21.21.41.31.3-1.31.31.2-1.2
Bone: trabecular number1.42.22.71.61.41.51.61.61.41.5-1.41.21.4-1.4
Bone: trabecular spacing2.53.23.8-1.7-1.6-1.9-1.7-1.6-1.9-1.81.9-2.0-1.81.8
Bone: trabecular thickness0.00.10.1-0.1-0.3-0.2-0.2-0.2-0.1-0.20.2-0.1-0.30.4
Bone: trabecular tissue density0.00.00.10.20.20.10.20.20.20.2-0.20.20.1-0.1
Water consumed over 24 hours0.81.01.30.80.81.00.90.91.01.0-1.11.01.1-1.1
Number of responses in last shaping day0.20.20.5-0.70.4-0.5-0.5-0.5-0.4-0.20.2-0.50.2-0.2