Hub : Genes

Clu

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Clu 0.27 0.13 1.7e-10 0.19 0.16 0.16 0.17 3.7e-10 9.2e-09 5.9e-09 1.5e-09
2 IC gene expression Clu 0.3 0.12 8.3e-11 0.19 0.22 0.21 0.22 2.1e-08 1.2e-09 2.2e-09 1.1e-09
3 NAcc gene expression Clu 0.18 0.08 0.0e+00 0.16 0.13 0.18 0.17 3.0e-24 3.6e-19 3.5e-26 1.1e-25
4 OFC gene expression Clu 0.39 0.18 6.6e-05 0.12 0.12 0.11 0.12 9.0e-04 9.9e-04 1.6e-03 1.1e-03
5 LHb mRNA stability Clu 0.58 0.15 3.9e-11 0.26 0.32 0.29 0.3 7.5e-07 2.7e-08 1.2e-07 5.8e-08
6 Brain gene expression Clu 0.29 0.1 0.0e+00 0.23 0.33 0.32 0.33 7.2e-21 1.2e-31 2.7e-30 9.1e-32
7 PL gene expression Clu 0.2 0.09 0.0e+00 0.22 0.23 0.22 0.06 1.3e-23 2.7e-24 5.3e-24 2.0e-07
8 Liver gene expression Clu 0.29 0.15 0.0e+00 0.21 0.24 0.25 0.24 2.6e-23 7.0e-27 4.5e-27 2.0e-26
9 Adipose isoform ratio NM_053021.3 0.04 0.04 3.3e-04 0.02 0.03 0.03 0.03 1.9e-03 2.7e-04 8.4e-04 1.3e-04
10 PL mRNA stability Clu 0.53 0.1 0.0e+00 0.62 0.63 0.63 0.58 4.6e-87 6.9e-89 9.8e-90 6.9e-77
11 Adipose isoform ratio XM_006252094.5 0.04 0.03 7.2e-04 0.02 0.03 0.02 0.03 3.2e-03 5.4e-04 1.4e-03 2.6e-04
12 pVTA mRNA stability Clu 0.52 0.11 0.0e+00 0.41 0.25 0.43 0.19 5.1e-35 4.5e-20 5.1e-37 5.3e-15
13 RMTg alternative TSS NM_053021.3 0.13 0.09 5.5e-03 0.06 0.07 0.04 0.06 1.1e-02 5.4e-03 3.5e-02 1.1e-02
14 BLA mRNA stability Clu 0.48 0.12 0.0e+00 0.32 0.31 0.31 0.32 1.9e-17 4.2e-17 5.0e-17 1.6e-17
15 RMTg alternative TSS XM_006252094.5 0.15 0.09 3.5e-03 0.07 0.09 0.05 0.07 8.0e-03 2.9e-03 1.9e-02 6.7e-03
16 IC mRNA stability Clu 0.54 0.14 0.0e+00 0.44 0.28 0.37 0.05 3.4e-20 2.4e-12 2.5e-16 2.9e-03
17 NAcc isoform ratio NM_053021.3 0.02 0.02 4.9e-03 0 0 0 0 8.3e-02 2.0e-01 2.2e-01 3.0e-01
18 NAcc isoform ratio XM_006252094.5 0.03 0.04 5.7e-03 0 0 0 -0 8.7e-02 2.9e-01 2.9e-01 5.7e-01
19 Brain mRNA stability Clu 0.49 0.1 0.0e+00 0.63 0.64 0.63 0.63 6.2e-75 2.6e-76 7.4e-76 3.8e-76
20 NAcc mRNA stability Clu 0.32 0.09 0.0e+00 0.41 0.1 0.4 0.03 1.7e-67 4.8e-15 3.7e-64 1.7e-05
21 IC intron excision ratio chr15_44366276_44367860 0.11 0.07 2.4e-04 0.07 0.05 0.06 0.05 7.3e-04 2.6e-03 2.2e-03 4.6e-03
22 OFC mRNA stability Clu 0.66 0.14 4.6e-12 0.24 0.24 0.25 0.27 2.0e-06 1.8e-06 1.1e-06 4.3e-07
23 pVTA gene expression Clu 0.04 0.03 6.1e-03 0 0.01 0.01 0.01 1.4e-01 6.1e-02 2.8e-02 3.0e-02
24 IL mRNA stability Clu 0.81 0.11 1.1e-16 0.41 0.33 0.41 0.3 7.7e-11 1.3e-08 5.4e-11 6.3e-08
25 Adipose gene expression Clu 0.75 0.11 0.0e+00 0.16 0.23 0.22 0.23 2.4e-17 1.9e-25 1.7e-24 2.1e-25
26 Adipose mRNA stability Clu 0.04 0.04 4.4e-04 0.01 0.02 0.02 0.02 8.3e-03 3.3e-03 1.6e-03 6.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.12.03.70.2-0.50.90.2-1.2-0.8-1.2-1.7-1.91.61.91.6-1.7-1.61.71.51.6-1.6-1.61.51.4-1.7-1.11.51.71.1
Area under the delay curve0.30.42.31.1-0.40.21.1-0.1-0.4-0.10.21.5-0.3-1.5-0.40.30.4-0.3-0.5-0.30.30.3-0.4-0.00.80.5-0.1-1.10.4
BMI with tail0.20.71.0-0.90.8-0.8-0.80.90.90.91.00.5-1.0-0.5-0.90.90.9-0.9-0.9-0.90.90.9-0.9-1.00.80.1-0.8-0.6-0.7
BMI without tail0.31.53.5-1.91.8-1.7-1.71.51.71.61.10.6-1.3-0.6-1.21.01.3-1.0-1.2-1.21.21.1-1.2-1.30.6-1.0-1.0-0.5-0.3
Body weight0.10.31.50.9-0.70.61.0-0.1-0.5-0.10.60.3-0.5-0.3-0.40.50.3-0.5-0.3-0.30.30.5-0.4-0.40.91.2-0.3-0.90.0
Weight adjusted by age0.30.84.42.1-1.51.22.1-0.7-1.1-0.70.3-0.5-0.00.50.10.20.0-0.2-0.20.2-0.20.00.10.10.61.9-0.2-0.1-1.3
Bone surface1.22.43.91.0-1.31.50.8-1.6-1.3-1.6-1.7-2.01.72.01.7-1.7-1.71.71.61.7-1.7-1.71.71.6-1.5-0.31.61.51.1
Bone volume1.22.44.20.8-1.21.40.8-1.6-1.3-1.5-1.7-2.11.72.11.7-1.7-1.71.71.61.7-1.7-1.71.61.6-1.5-0.31.51.60.9
Breakpoint value in progressive ratio session0.00.10.50.1-0.20.30.2-0.20.0-0.2-0.10.70.2-0.70.1-0.1-0.10.1-0.30.2-0.2-0.10.20.2-0.20.60.1-0.1-0.3
Number of licking bursts0.10.31.0-0.90.9-0.8-1.00.60.80.60.10.2-0.3-0.1-0.30.20.4-0.2-0.3-0.40.40.3-0.4-0.4-0.0-1.0-0.30.0-0.3
Context. condit. distance diff. score3.03.612.6-3.53.3-3.0-3.52.32.92.30.80.8-1.3-0.8-1.30.91.3-0.9-1.3-1.31.31.1-1.4-1.60.1-3.1-1.2-0.2-0.2
Locomotion velocity, session 10.70.81.20.9-0.81.00.9-1.0-1.1-1.0-0.8-0.81.00.81.0-0.8-1.00.81.11.1-1.1-1.01.00.8-0.80.70.61.0-0.3
Locomotion distance, session 12.43.15.32.2-2.12.32.1-2.1-2.3-2.1-1.5-1.11.81.11.9-1.5-1.91.51.91.9-1.9-1.71.91.4-1.21.61.51.20.7
Locomotion velocity, session 21.11.42.71.6-1.51.61.4-1.4-1.5-1.4-0.9-0.91.20.81.2-0.9-1.20.91.21.3-1.3-1.11.20.9-0.71.30.90.80.1
Locomotion distance, session 23.54.98.22.6-2.52.82.6-2.6-2.9-2.6-1.9-1.82.21.82.3-1.9-2.31.92.52.5-2.5-2.22.41.8-1.61.82.01.60.8
Locomotion velocity, session 31.61.92.8-0.61.2-1.2-0.51.51.01.51.61.5-1.6-1.5-1.51.61.5-1.6-1.3-1.41.41.6-1.5-1.71.40.1-1.5-1.2-1.3
Locomotion distance, session 30.70.81.5-0.81.2-1.1-0.71.01.01.10.80.9-1.0-0.9-0.90.81.0-0.8-1.0-0.90.90.9-0.8-1.10.6-0.7-0.8-0.4-0.7
Stereotopy head waving bouts, day 30.10.11.20.6-0.40.40.4-0.2-0.4-0.20.20.20.0-0.2-0.00.2-0.1-0.20.20.1-0.10.1-0.1-0.10.21.1-0.2-0.1-0.5
Stereotopy head waving duration, day 30.60.72.70.8-0.40.20.60.3-0.20.31.11.1-0.8-1.1-0.81.10.6-1.1-0.5-0.70.70.9-0.9-0.81.21.6-0.9-1.1-0.9
Locomotion velocity, session 73.03.314.0-3.73.2-2.9-3.72.02.82.10.20.1-0.9-0.1-0.90.30.9-0.3-0.9-1.11.10.7-1.0-0.8-0.5-3.7-0.50.20.6
Locomotion distance, session 71.72.112.6-3.12.4-2.0-2.81.01.81.0-0.8-1.10.21.10.1-0.7-0.10.80.1-0.10.1-0.40.10.2-1.6-3.50.51.21.2
Stereotopy head waving bouts, day 70.50.53.11.2-0.90.71.1-0.2-0.7-0.20.70.8-0.4-0.8-0.40.70.3-0.7-0.1-0.30.30.5-0.4-0.41.11.8-0.5-0.8-0.7
Stereotopy head waving duration, day 71.11.43.21.0-0.40.10.80.5-0.10.51.41.6-1.2-1.6-1.11.41.0-1.4-0.9-1.01.01.3-1.1-1.21.81.8-1.2-1.4-1.3
Locomotion velocity, session 80.50.61.0-0.81.0-0.8-0.80.90.80.80.70.9-0.7-0.8-0.60.70.7-0.7-0.6-0.60.60.7-0.7-1.00.6-0.3-0.9-0.4-0.9
Locomotion distance, session 80.20.31.1-0.80.8-0.3-0.8-0.00.2-0.0-0.6-0.40.40.40.5-0.5-0.50.50.60.6-0.6-0.50.5-0.2-0.8-1.00.40.80.5
Degree of sensitization distance2.02.28.9-2.31.3-1.0-2.20.10.90.1-1.5-1.91.11.90.9-1.5-1.01.50.90.7-0.7-1.20.81.1-2.1-3.01.21.61.9
Degree of sensitization stereotypy0.60.71.80.7-0.40.10.60.3-0.10.31.01.2-0.8-1.2-0.81.00.7-1.0-0.6-0.70.70.9-0.8-0.71.31.2-0.8-1.1-0.7
Conditioned locomotion0.30.31.7-1.31.2-1.0-1.10.70.80.70.10.1-0.2-0.1-0.20.10.2-0.1-0.2-0.20.20.1-0.2-0.5-0.4-0.8-0.30.5-0.4
Cocaine response after cond. corrected1.42.24.8-2.02.2-2.1-2.01.82.01.81.20.9-1.3-0.9-1.31.11.4-1.1-1.4-1.31.31.2-1.4-1.30.7-1.3-1.4-0.4-1.5
Cocaine response after cond. not corrected0.71.02.7-1.51.6-1.4-1.71.21.51.20.70.6-0.8-0.6-0.80.70.9-0.7-0.9-0.80.80.7-0.8-1.00.3-0.9-0.8-0.1-1.0
Cocaine response before conditioning2.02.43.61.5-1.81.91.5-1.9-1.8-1.9-1.5-1.31.61.21.6-1.5-1.61.51.61.6-1.6-1.51.61.5-1.21.01.60.91.5
Saline control response1.11.53.01.6-1.71.61.7-1.4-1.7-1.4-0.9-1.01.11.01.1-1.0-1.21.01.31.2-1.2-1.01.11.4-0.60.91.10.60.9
Bone: connectivity density1.82.95.5-0.40.00.6-0.5-1.2-0.6-1.2-2.1-2.31.92.31.9-2.0-1.82.01.91.9-1.9-2.01.81.5-2.2-1.71.72.31.2
Bone: cortical apparent density1.01.52.8-1.31.4-1.7-1.31.61.51.61.20.6-1.3-0.5-1.41.11.3-1.1-1.1-1.41.41.2-1.4-1.01.0-1.3-1.2-0.8-0.4
Bone: cortical area0.20.31.21.1-1.10.90.9-0.6-0.7-0.6-0.2-0.10.30.10.2-0.2-0.30.20.20.3-0.3-0.20.30.40.20.60.4-0.40.5
Bone: cortical porosity0.40.42.41.4-1.00.91.2-0.5-0.8-0.50.20.50.0-0.50.10.2-0.0-0.2-0.00.1-0.10.10.10.10.51.5-0.0-0.5-0.3
Bone: cortical porosity0.50.63.11.8-1.41.21.5-0.7-1.0-0.70.20.40.1-0.40.10.2-0.1-0.20.10.2-0.20.00.20.30.61.70.1-0.6-0.1
Bone: cortical thickness0.10.20.70.5-0.40.20.40.1-0.00.10.40.5-0.4-0.5-0.40.40.4-0.4-0.5-0.40.40.4-0.4-0.10.70.4-0.3-0.80.1
Bone: cortical thickness0.81.01.5-1.11.2-1.1-1.11.21.21.20.90.8-1.0-0.8-1.00.91.0-0.9-1.0-1.01.01.0-1.0-1.00.8-0.9-0.8-0.8-0.5
Bone: cortical tissue density1.11.83.3-1.51.6-1.8-1.41.71.61.71.30.7-1.4-0.6-1.51.21.4-1.2-1.2-1.51.51.3-1.5-1.21.1-1.4-1.3-0.9-0.5
Condit. Reinf. active minus inactive responses0.30.31.31.1-1.00.91.0-0.7-1.0-0.7-0.2-0.30.30.30.3-0.2-0.40.20.60.4-0.4-0.30.40.30.11.00.2-0.0-0.1
Condit. Reinf. active-inactive response ratio0.30.31.1-0.10.3-0.3-0.30.40.30.40.60.7-0.5-0.7-0.50.70.5-0.7-0.3-0.50.50.6-0.5-0.80.60.6-0.7-0.5-1.0
Condit. Reinf. active responses1.31.73.11.7-1.81.71.6-1.6-1.8-1.5-1.1-1.21.21.21.2-1.1-1.31.11.41.3-1.3-1.21.21.3-0.61.01.00.70.6
Condit. Reinf. inactive responses3.64.76.12.0-2.32.32.0-2.5-2.4-2.4-2.2-2.32.22.32.2-2.2-2.22.22.22.3-2.3-2.22.22.5-1.70.42.11.61.9
Incentive salience index mean0.81.03.81.9-1.81.61.8-1.2-1.6-1.2-0.3-0.50.50.50.6-0.4-0.60.30.90.6-0.6-0.50.60.70.21.60.4-0.0-0.1
Condit. Reinf. lever presses1.31.95.72.3-2.42.12.2-1.7-2.1-1.7-0.7-1.01.11.01.1-0.8-1.10.81.31.1-1.1-0.91.11.3-0.11.70.80.20.2
Condit. Reinf. active minus inactive responses0.40.61.00.3-0.60.70.4-0.8-0.6-0.9-1.0-0.51.00.50.9-0.9-0.90.90.71.0-1.0-0.91.00.9-1.0-0.10.80.80.6
Condit. Reinf. active-inactive response ratio0.10.20.7-0.50.4-0.4-0.40.50.50.40.40.8-0.4-0.8-0.40.50.5-0.5-0.5-0.40.40.4-0.4-0.40.2-0.1-0.3-0.4-0.1
Condit. Reinf. active responses0.81.11.70.4-0.60.80.5-1.0-0.7-1.0-1.3-1.01.21.01.2-1.2-1.11.21.01.2-1.2-1.21.21.2-1.3-0.31.11.11.0
Condit. Reinf. inactive responses1.72.54.30.4-0.71.00.4-1.5-1.1-1.4-1.9-2.11.82.11.7-1.9-1.71.91.71.7-1.7-1.81.81.7-1.9-0.61.51.81.3
Condit. Reinf. lever presses0.60.92.01.4-1.41.31.4-1.1-1.3-1.1-0.7-0.60.80.60.8-0.7-0.90.70.80.8-0.8-0.70.80.9-0.40.90.90.20.9
Condit. Reinf. lever reinforcers received0.50.71.10.4-0.60.70.5-0.9-0.6-0.9-1.1-0.71.00.61.0-1.0-0.91.00.71.0-1.0-1.01.00.9-1.0-0.20.90.81.0
Conditioned reinforcement - actives0.10.42.1-1.30.8-0.6-1.50.20.60.2-0.5-0.20.40.20.3-0.5-0.30.50.40.2-0.2-0.30.20.2-0.8-1.10.40.40.7
Conditioned reinforcement - inactives0.51.32.3-0.4-0.30.5-0.5-1.0-0.6-0.9-1.4-1.51.31.51.2-1.3-1.41.31.31.1-1.1-1.21.11.2-1.3-0.71.31.01.5
Conditioned locomotion0.71.02.9-1.41.2-1.2-1.71.11.51.00.61.2-0.8-1.2-0.90.80.9-0.8-1.1-0.90.90.9-0.9-0.90.5-0.8-0.6-1.10.2
Patch foraging indifference point 0 sec3.29.013.03.1-3.53.63.0-3.6-3.5-3.6-3.1-1.83.11.83.2-2.9-3.12.93.03.1-3.1-3.03.23.2-2.51.53.31.73.1
Patch foraging indifference point AUC1.74.05.2-1.92.1-2.3-1.72.22.22.21.92.1-2.1-2.1-2.22.12.1-2.0-2.1-2.32.32.1-2.2-2.11.6-0.7-2.0-1.7-1.1
Delay disc. indifference point, 0s delay2.22.54.11.9-1.71.81.9-1.9-2.0-1.9-1.7-0.91.80.91.7-1.6-1.71.61.71.7-1.7-1.61.71.7-1.10.61.60.91.1
Delay disc. indifference point, 16s delay0.30.42.60.30.5-0.60.20.40.20.40.31.6-0.6-1.6-0.60.40.5-0.4-0.6-0.60.60.5-0.5-0.40.5-0.3-0.0-0.90.9
Delay disc. indifference point, 2s delay1.31.54.82.2-1.71.72.2-1.5-1.9-1.6-0.90.31.1-0.31.0-0.7-1.00.71.11.0-1.0-0.91.00.9-0.21.70.8-0.10.1
Delay disc. indifference point, 24s delay0.40.74.20.00.5-0.60.10.60.10.50.62.0-0.5-2.1-0.70.70.6-0.7-0.3-0.80.80.7-0.8-0.50.90.1-0.3-1.40.4
Delay disc. indifference point, 4s delay0.91.02.50.9-0.1-0.21.00.60.00.61.21.1-1.1-1.1-1.11.11.0-1.1-1.1-1.11.11.1-1.1-0.81.61.0-1.0-1.4-0.9
Delay disc. indifference point, 8s delay0.20.41.50.5-0.0-0.30.30.30.40.40.41.2-0.7-1.2-0.70.50.8-0.5-1.1-0.60.60.6-0.6-0.20.8-0.2-0.4-1.10.3
Indifference point function ln k0.72.04.22.1-1.61.71.8-1.6-1.8-1.6-1.2-1.51.31.41.5-1.3-1.31.31.41.6-1.6-1.41.41.3-0.80.71.31.00.8
Indifference point function log k0.72.04.22.1-1.61.71.8-1.6-1.8-1.6-1.2-1.51.31.41.5-1.3-1.31.31.41.6-1.6-1.41.41.3-0.80.71.31.00.8
Patch foraging total patch changes 0 sec2.78.012.63.2-3.53.63.2-3.4-3.4-3.4-2.8-1.72.81.62.9-2.6-2.92.62.82.8-2.8-2.72.93.0-2.11.73.11.32.9
Patch foraging total patch changes 12 sec0.71.01.71.1-1.31.21.2-1.3-1.2-1.3-1.10.11.1-0.10.9-0.9-1.00.90.80.8-0.8-0.91.01.1-0.80.81.20.11.3
Patch foraging total patch changes 18 sec0.10.21.30.1-0.20.30.3-0.5-0.4-0.5-0.70.20.4-0.20.4-0.5-0.40.50.30.3-0.3-0.40.40.4-0.4-0.30.6-0.11.1
Patch foraging total patch changes 24 sec0.51.53.71.8-1.91.91.6-1.6-1.5-1.7-1.20.11.1-0.11.1-0.9-1.10.90.81.0-1.0-1.01.11.1-0.51.51.4-0.21.4
Patch foraging total patch changes 6 sec0.20.30.90.3-0.70.60.3-0.7-0.5-0.7-0.7-0.10.60.00.5-0.5-0.60.50.40.4-0.4-0.50.50.8-0.60.40.7-0.01.0
Patch foraging time to switch 0 sec0.21.01.7-0.1-0.40.5-0.1-0.8-0.5-0.8-1.2-1.11.31.11.1-1.2-1.11.21.11.1-1.1-1.21.11.3-1.3-0.41.01.30.2
Patch foraging water rate 0 sec0.10.31.21.1-0.60.61.1-0.2-0.7-0.20.30.4-0.2-0.4-0.10.40.1-0.40.00.0-0.00.3-0.1-0.40.61.0-0.1-0.60.1
Patch foraging water rate 12 sec0.10.42.41.4-1.01.01.5-0.6-1.1-0.60.0-0.50.10.50.2-0.0-0.20.00.40.4-0.4-0.10.20.20.41.00.1-0.1-0.2
Patch foraging water rate 18 sec1.32.86.00.80.2-0.60.71.30.51.32.21.5-2.1-1.4-2.02.11.9-2.1-1.8-1.81.82.1-1.9-1.92.41.2-1.7-2.2-1.2
Patch foraging water rate 24 sec0.70.91.8-0.51.1-1.0-0.21.10.71.21.20.3-1.3-0.2-1.11.01.1-1.0-0.9-1.11.11.1-1.0-1.31.1-0.6-1.1-0.6-0.9
Patch foraging water rate 6 sec0.71.04.52.0-1.00.92.1-0.2-1.1-0.30.90.8-0.6-0.8-0.60.90.4-0.9-0.3-0.40.40.7-0.5-0.61.61.7-0.7-1.3-0.4
Seeking ratio, delayed vs. immediate footshock1.82.63.70.8-1.71.80.5-1.8-1.5-1.8-1.7-1.81.81.71.8-1.6-1.91.61.91.9-1.9-1.71.71.5-1.30.31.51.31.0
Distance traveled before self-admin0.20.53.41.2-1.10.81.3-0.3-0.7-0.30.50.6-0.2-0.6-0.30.50.3-0.5-0.4-0.30.30.4-0.4-0.20.91.9-0.4-0.9-0.6
Distance traveled after self-admin0.51.02.91.5-0.60.21.70.2-0.60.21.01.5-0.8-1.5-0.81.00.6-1.0-0.5-0.60.60.8-0.8-0.71.31.4-0.9-1.3-0.7
Extensor digitorum longus weight5.120.441.81.40.4-1.41.33.11.63.05.66.5-4.8-6.5-4.75.54.6-5.5-4.7-4.64.65.0-4.6-4.95.84.9-4.6-5.3-4.8
Bone: elastic displacement1.62.03.41.7-1.81.81.6-1.7-1.8-1.7-1.3-1.21.51.21.4-1.3-1.61.21.51.4-1.4-1.41.51.2-0.91.01.30.90.8
Bone: elastic work2.73.57.62.8-2.72.72.6-2.4-2.6-2.4-1.5-1.31.71.31.8-1.5-1.91.51.71.8-1.8-1.61.81.6-0.81.71.60.80.9
Bone: endosteal estimation0.30.61.10.9-1.01.01.0-1.0-0.9-0.9-0.8-0.80.80.70.8-0.8-0.80.80.60.8-0.8-0.80.80.8-0.60.30.80.50.5
Bone: endosteal perimeter1.02.43.71.6-1.81.91.5-1.9-1.8-1.9-1.6-1.41.71.41.7-1.5-1.71.51.61.7-1.7-1.61.71.4-1.30.91.51.10.9
Epididymis fat weight0.10.51.10.3-0.10.30.4-0.6-0.6-0.6-0.9-0.60.70.60.7-0.9-0.80.90.80.8-0.8-0.90.70.8-0.8-0.90.80.81.1
Delta time in closed arm before/after self-admin0.80.81.7-0.20.00.3-0.1-0.7-0.4-0.6-1.2-1.01.01.01.0-1.1-0.91.10.91.0-1.0-1.01.00.6-1.3-0.90.91.30.9
Delta time in open arm before/after self-admin0.10.10.3-0.60.0-0.1-0.30.30.40.20.30.1-0.3-0.1-0.40.40.3-0.4-0.5-0.30.30.4-0.2-0.20.30.3-0.3-0.3-0.4
Diff in mean of infusions in LGA sessions0.30.63.01.7-1.00.91.5-0.7-1.1-0.70.0-1.00.41.00.3-0.2-0.50.20.50.5-0.5-0.30.30.40.21.3-0.00.5-0.8
Delay discount exponential model param0.60.83.4-1.10.30.0-1.1-0.20.2-0.2-0.6-1.80.71.80.8-0.7-0.80.70.90.7-0.7-0.70.80.4-1.2-0.70.41.6-0.1
Extinction: sum of active levers before priming0.40.61.70.7-0.50.60.5-0.7-0.7-0.7-1.0-0.70.70.70.8-0.9-0.90.90.80.8-0.8-0.90.80.8-0.8-0.51.00.61.3
Active lever presses in extinction session 60.70.71.7-1.11.3-1.2-1.11.11.01.10.50.5-0.8-0.4-0.70.60.7-0.6-0.6-0.70.70.7-0.9-0.60.2-1.3-0.5-0.40.0
Bone: final force0.10.20.90.9-0.90.70.9-0.4-0.5-0.5-0.10.00.2-0.00.1-0.1-0.10.1-0.10.1-0.1-0.10.20.50.10.50.2-0.30.1
Bone: final moment0.30.52.01.4-1.41.11.4-0.8-0.9-0.9-0.3-0.30.50.30.4-0.4-0.40.40.20.4-0.4-0.40.50.90.00.80.4-0.10.3
Food consumed during 24 hour testing period0.10.31.21.0-1.00.71.1-0.3-0.7-0.30.20.0-0.2-0.0-0.10.2-0.0-0.20.1-0.10.10.2-0.10.10.80.30.1-0.80.9
Glucose1.42.33.6-1.21.4-1.6-1.11.71.71.71.41.3-1.8-1.2-1.71.51.8-1.5-1.9-1.71.71.6-1.7-1.61.4-0.9-1.2-1.5-0.3
Heart weight0.30.51.4-0.2-0.10.1-0.3-0.4-0.2-0.4-0.8-1.20.71.20.6-0.8-0.70.80.80.7-0.7-0.70.70.9-0.8-1.00.41.10.4
Delay discount hyperbolic model param0.50.72.6-1.30.5-0.2-1.3-0.10.4-0.0-0.5-1.60.61.60.6-0.6-0.60.60.70.6-0.6-0.60.60.4-1.1-0.90.41.40.0
Intermittent access intake day 1-15 change0.10.31.6-0.00.3-0.10.2-0.3-0.3-0.3-0.7-0.50.70.50.6-0.7-0.70.70.60.4-0.4-0.70.60.5-0.7-1.30.50.90.6
Intermittent access intake escalation0.00.31.40.10.3-0.10.3-0.3-0.2-0.3-0.6-0.50.60.50.5-0.6-0.60.60.40.2-0.2-0.60.60.4-0.6-1.20.40.80.4
Intermittent access intake escalation 20.10.11.10.20.4-0.40.20.1-0.00.1-0.1-0.40.10.40.1-0.1-0.10.10.1-0.10.1-0.10.1-0.1-0.2-1.0-0.10.6-0.1
Intermitt. access day 1 inactive lever presses0.10.73.6-1.00.4-0.4-1.60.00.60.0-0.5-1.90.71.90.5-0.6-0.60.60.50.4-0.4-0.60.50.6-1.0-0.90.31.4-0.3
Intermitt. access day 15 inactive lever presses0.21.11.7-0.91.3-1.2-0.91.21.11.31.2-0.8-1.20.9-1.11.11.0-1.1-1.2-1.11.11.1-1.1-1.10.9-0.8-1.3-0.2-0.9
Intermitt. access escalation Index0.20.61.1-0.4-0.60.8-0.2-0.8-0.5-0.8-0.8-0.60.90.61.0-0.9-0.90.90.91.1-1.1-0.90.80.8-0.90.10.90.70.6
Intermittent access day 1 total infusions0.10.41.7-0.40.1-0.3-0.30.40.30.30.31.2-0.5-1.2-0.50.50.5-0.5-0.2-0.40.40.6-0.6-0.70.60.2-0.0-1.30.8
Intermittent access day 15 total infusions0.10.21.4-0.80.8-0.7-0.70.30.40.3-0.20.10.0-0.1-0.0-0.1-0.10.10.1-0.10.1-0.0-0.0-0.3-0.3-1.20.20.00.7
Intermittent access terminal intake (last 3 days)0.50.92.1-1.21.4-1.4-1.21.11.11.10.60.7-0.9-0.7-1.00.80.8-0.8-0.8-1.01.00.9-0.9-1.20.5-1.2-0.7-0.80.2
Intermittent access total infusions0.40.52.2-1.51.2-1.1-1.50.70.90.7-0.00.4-0.3-0.4-0.40.10.3-0.1-0.1-0.30.30.3-0.4-0.6-0.2-1.2-0.1-0.30.6
Intermittent access day 1 locomotion0.20.41.10.2-0.80.7-0.2-0.7-0.4-0.7-0.70.10.7-0.10.6-0.6-0.60.60.70.7-0.7-0.50.50.5-0.50.50.8-0.21.0
Intermittent access day 15 total locomotion0.20.91.5-0.71.1-1.2-0.51.10.91.20.90.5-1.1-0.5-1.10.91.0-0.9-1.0-1.21.21.1-1.1-1.10.9-0.8-0.9-0.9-0.1
Intermittent access total locomotion0.10.10.3-0.40.1-0.4-0.60.20.40.30.10.0-0.2-0.0-0.30.20.2-0.2-0.3-0.20.20.3-0.3-0.20.1-0.2-0.2-0.40.3
Intermittent access standard deviation0.31.83.10.20.6-0.90.21.30.71.31.51.1-1.7-1.1-1.61.61.6-1.6-1.4-1.61.61.7-1.6-1.61.8-0.4-1.6-1.6-0.5
Left kidney weight0.00.21.70.8-1.30.90.8-0.4-0.4-0.40.1-0.5-0.20.5-0.10.20.2-0.2-0.4-0.00.00.2-0.10.10.50.7-0.1-0.60.3
Right kidney weight0.31.96.02.0-2.52.11.9-1.7-1.7-1.6-1.0-1.51.11.51.1-0.9-1.10.90.91.2-1.2-0.91.01.3-0.51.41.00.41.1
Cocaine induced anxiety0.51.54.21.4-2.11.91.5-1.6-1.6-1.6-0.9-0.61.10.61.1-0.9-1.00.91.01.2-1.2-1.01.11.2-0.71.70.90.40.5
Post-drug Anxiety4.24.76.61.5-2.32.41.5-2.6-2.1-2.5-2.3-1.72.31.72.4-2.4-2.32.42.12.5-2.5-2.42.52.4-2.30.82.12.01.4
Baseline Anxiety0.30.52.0-0.30.3-0.1-0.3-0.4-0.1-0.3-1.0-0.50.70.50.7-0.9-0.80.90.70.7-0.7-0.80.80.6-1.0-1.40.81.00.9
Tail length0.21.32.60.9-1.11.20.8-1.3-1.1-1.2-1.2-1.21.11.21.2-1.2-1.11.21.01.2-1.2-1.11.11.4-1.0-0.21.30.71.6
Length with tail0.62.75.42.3-2.22.32.2-2.0-2.2-1.9-1.4-1.51.51.41.5-1.4-1.61.31.61.7-1.7-1.41.51.7-0.81.11.40.81.1
Length without tail0.21.36.42.5-2.01.82.4-0.9-1.6-1.00.30.00.1-0.10.10.3-0.2-0.30.30.2-0.20.10.10.20.92.50.2-0.9-0.2
Times rat made contact with spout0.10.21.0-0.50.4-0.5-0.50.40.40.40.2-0.0-0.40.0-0.30.20.3-0.2-0.2-0.40.40.3-0.3-0.30.3-1.0-0.2-0.30.5
Lifetime Intake0.40.51.9-1.31.0-1.0-1.40.70.80.70.20.7-0.4-0.6-0.50.30.4-0.3-0.2-0.40.40.5-0.5-0.80.1-0.9-0.2-0.60.5
Liver weight, left0.50.94.52.1-1.91.51.9-0.6-1.1-0.60.6-0.2-0.20.2-0.20.50.1-0.5-0.1-0.10.10.3-0.2-0.01.22.1-0.2-0.9-0.6
Liver weight, right1.52.74.4-0.30.6-1.0-0.11.61.11.52.01.8-2.0-1.8-1.92.01.9-2.0-1.8-1.91.91.9-1.9-1.52.10.4-1.5-2.1-0.8
Locomotor activity2.54.014.03.7-3.43.13.6-2.4-3.2-2.4-0.9-0.81.30.81.3-0.9-1.50.91.61.5-1.5-1.11.31.5-0.03.21.00.00.6
Locomotor testing distance4.410.917.23.8-3.94.13.6-3.9-4.2-3.9-3.1-2.43.52.33.4-3.1-3.53.13.63.6-3.6-3.33.43.5-2.42.13.02.12.0
Locomotor testing rearing4.115.023.24.1-4.64.84.1-4.6-4.8-4.6-3.6-2.94.12.84.0-3.6-4.23.64.34.2-4.2-3.94.04.1-2.72.43.72.42.4
Locomotion in novel chamber0.10.11.3-0.1-0.0-0.0-0.3-0.10.1-0.1-0.40.70.1-0.70.2-0.30.00.3-0.10.1-0.1-0.20.10.3-0.4-0.50.5-0.21.1
Locomotion in novel chamber post-restriction0.30.84.00.10.3-0.30.30.50.30.40.62.0-0.8-2.0-0.71.00.9-1.0-0.9-0.80.80.8-0.7-1.00.70.6-0.5-1.3-0.1
Fecal boli incidents, locomotor time 10.61.54.20.6-0.2-0.50.90.90.30.91.51.3-1.3-1.3-1.61.41.4-1.4-1.5-1.31.31.4-1.6-0.61.70.5-1.1-2.10.2
Change in fecal boli incidents, locomotor task0.30.31.7-0.90.6-0.4-0.90.20.30.30.0-1.20.01.20.3-0.2-0.10.20.4-0.00.0-0.20.40.0-0.7-0.2-0.11.3-1.0
Time >=10cm from walls, locomotor time 11.01.23.50.8-1.01.00.2-1.1-0.6-1.0-1.1-1.90.91.91.2-1.2-0.91.20.81.1-1.1-1.11.21.4-1.3-0.31.01.40.6
Bouts of movement, locomotor time 10.70.94.1-0.40.5-0.7-0.40.90.80.81.11.0-0.7-1.0-0.91.11.0-1.1-1.1-0.80.81.0-0.9-0.80.90.5-1.3-0.6-2.0
Total resting periods, locomotor time 11.61.84.5-1.01.3-1.3-1.01.41.41.41.51.5-1.2-1.5-1.31.51.5-1.5-1.4-1.21.21.4-1.3-1.41.10.1-1.7-0.8-2.1
Rest time, locomotor task time 11.11.83.3-1.31.6-1.5-1.11.51.51.51.21.8-1.2-1.8-1.21.41.3-1.3-1.3-1.21.21.3-1.2-1.50.8-0.5-1.2-0.8-1.3
Distance moved, locomotor task time 10.51.32.70.5-0.91.00.3-1.2-0.8-1.1-1.3-1.71.11.61.2-1.4-1.21.41.11.1-1.1-1.31.31.3-1.2-0.11.31.11.1
Vertical activity count, locomotor time 10.31.84.92.1-2.22.01.9-1.7-1.9-1.7-0.8-0.71.00.71.1-0.9-1.10.91.10.9-0.9-1.01.01.1-0.42.01.20.10.9
Time >=10cm from walls, locomotor time 20.00.10.30.3-0.20.00.10.2-0.00.20.5-0.4-0.50.4-0.20.30.3-0.3-0.1-0.30.30.3-0.4-0.10.30.5-0.3-0.0-0.4
Bouts of movement, locomotor time 20.61.94.6-0.41.3-1.3-0.21.50.91.51.81.2-1.5-1.2-1.51.61.4-1.6-1.2-1.31.31.5-1.6-1.71.60.3-1.9-0.8-2.2
Total resting periods, locomotor time 20.93.66.2-0.81.8-1.8-0.62.11.52.12.41.6-2.1-1.5-2.12.22.0-2.2-1.8-1.81.82.1-2.2-2.22.10.0-2.4-1.2-2.5
Rest time, locomotor task time 25.49.112.6-1.62.5-2.9-1.43.22.83.23.23.5-3.4-3.5-3.43.33.5-3.3-3.5-3.33.33.3-3.3-3.13.0-0.8-2.9-3.0-1.7
Distance moved, locomotor task time 23.24.35.71.4-2.02.11.2-2.3-2.0-2.3-2.4-2.02.12.02.3-2.3-2.32.32.22.2-2.2-2.32.22.1-2.00.32.41.52.0
Vertical activity count, locomotor time 21.33.16.42.1-2.52.52.1-2.2-2.4-2.2-1.5-0.61.60.51.7-1.4-1.81.41.91.8-1.8-1.61.51.6-0.81.81.80.21.8
Light reinforcement 10.10.53.5-0.30.3-0.2-0.3-0.2-0.0-0.2-0.8-0.80.50.80.5-0.8-0.60.80.70.5-0.5-0.60.50.5-0.6-1.90.70.71.4
Light reinforcement 20.92.15.4-2.12.1-2.2-1.91.91.91.91.10.4-1.3-0.3-1.41.01.2-1.0-1.1-1.31.31.2-1.5-1.20.9-2.3-1.3-0.3-0.5
Bone: marrow area0.30.71.10.9-1.01.10.9-1.0-0.9-1.0-0.9-0.80.90.80.8-0.8-0.90.80.70.9-0.9-0.90.90.9-0.70.20.90.60.6
Bone: maximum diameter0.10.20.60.6-0.40.30.50.1-0.20.00.50.7-0.4-0.7-0.40.50.3-0.5-0.3-0.40.40.5-0.4-0.50.80.7-0.3-0.8-0.0
Bone: maximum force0.20.52.61.6-1.41.11.6-0.7-0.9-0.70.00.10.2-0.20.1-0.0-0.1-0.0-0.10.2-0.2-0.10.20.50.41.20.2-0.5-0.1
Bone: maximum moment0.51.04.42.1-2.01.62.0-1.1-1.4-1.1-0.3-0.20.50.20.4-0.3-0.50.30.20.5-0.5-0.40.50.90.21.40.5-0.30.2
Mean time between licks in bursts0.63.46.3-0.1-0.41.0-0.3-1.6-0.9-1.5-2.4-2.52.22.52.1-2.3-2.02.31.92.0-2.0-2.22.11.6-2.3-1.31.82.41.1
Mean num. licks in bursts0.00.10.40.5-0.50.40.6-0.2-0.4-0.20.1-0.1-0.10.10.00.0-0.1-0.00.1-0.00.00.10.00.00.30.30.1-0.30.5
Cd content in liver0.60.64.21.6-1.31.11.7-0.5-1.1-0.60.40.1-0.1-0.1-0.10.30.0-0.4-0.10.2-0.20.2-0.2-0.00.72.1-0.2-0.6-0.4
Co content in liver2.32.74.2-0.40.9-1.2-0.11.61.01.62.11.6-1.9-1.5-1.92.01.8-2.0-1.7-1.81.81.9-1.9-1.92.00.9-1.8-1.7-1.7
Cu content in liver0.80.91.7-0.30.7-0.7-0.41.00.91.01.10.8-1.1-0.8-1.11.21.1-1.2-1.2-1.01.01.1-1.2-1.31.10.4-1.0-1.0-0.7
Fe content in liver1.41.74.1-0.2-0.20.6-0.1-1.0-0.7-0.9-1.5-2.01.42.01.4-1.5-1.51.61.41.3-1.3-1.51.31.1-1.7-0.91.11.90.7
K content in liver0.50.52.3-1.21.1-0.7-1.40.20.70.3-0.5-0.90.30.90.4-0.5-0.30.50.40.3-0.3-0.40.3-0.1-0.7-1.50.11.1-0.0
Mg content in liver0.50.61.5-0.60.4-0.0-0.7-0.4-0.0-0.4-1.0-0.60.80.60.9-0.9-0.80.90.90.8-0.8-0.80.80.4-1.1-1.20.81.00.9
Mn content in liver1.31.53.5-0.0-0.40.70.2-1.1-0.9-1.1-1.6-0.61.40.61.4-1.5-1.41.51.51.3-1.3-1.41.41.1-1.5-0.81.61.11.9
Na content in liver1.01.15.92.4-1.91.52.4-0.9-1.6-0.90.40.0-0.1-0.00.00.4-0.1-0.40.10.0-0.00.20.10.11.12.3-0.2-0.7-0.4
Rb content in liver0.10.20.7-0.60.6-0.4-0.60.30.40.40.1-0.8-0.10.8-0.1-0.00.10.0-0.1-0.00.00.0-0.1-0.4-0.2-0.6-0.20.6-0.2
Se content in liver4.85.77.92.0-2.42.72.0-2.8-2.7-2.7-2.5-2.02.72.02.6-2.4-2.72.42.82.7-2.7-2.52.52.4-2.01.12.12.11.2
Sr content in liver0.80.71.70.3-0.50.70.6-0.8-0.8-0.8-0.7-1.10.91.10.9-0.8-1.00.81.00.9-0.9-0.90.90.7-0.80.30.51.3-0.4
Zn content in liver0.80.91.50.6-0.81.00.6-1.1-1.0-1.1-1.1-0.81.10.81.1-1.0-1.11.01.21.2-1.2-1.01.10.9-0.90.41.00.80.7
Bone: minimum diameter0.40.83.21.8-1.71.51.6-1.1-1.3-1.1-0.3-0.10.50.10.4-0.3-0.60.30.40.5-0.5-0.40.50.70.11.30.6-0.40.7
Time in familiar zone, hab. session 10.10.10.2-0.40.2-0.1-0.20.0-0.0-0.0-0.3-0.40.30.40.2-0.3-0.30.30.40.3-0.3-0.30.20.5-0.3-0.40.10.50.1
Time in novel zone, hab. session 11.92.13.0-0.30.8-1.1-0.41.41.11.41.71.7-1.7-1.7-1.61.71.6-1.7-1.6-1.71.71.6-1.6-1.71.60.5-1.5-1.6-1.1
Total zone transitions, hab. session 10.30.51.61.3-1.21.11.2-0.9-1.1-0.9-0.3-0.30.50.30.5-0.3-0.60.30.70.6-0.6-0.40.50.4-0.01.00.40.10.2
Total locomotion distance, hab. session 11.21.72.71.5-1.61.61.2-1.6-1.6-1.6-1.2-1.21.41.21.4-1.2-1.41.21.51.4-1.4-1.31.31.2-0.80.91.10.80.6
Locomotion velocity, hab. session 12.94.16.12.2-2.32.51.8-2.4-2.4-2.4-1.9-1.92.21.92.1-1.9-2.21.92.42.2-2.2-2.02.11.9-1.41.11.81.41.0
Time in familiar zone, hab. session 20.70.82.0-1.31.4-1.4-0.91.11.21.10.60.6-0.7-0.6-0.80.60.8-0.6-1.0-0.90.90.7-0.8-0.70.2-1.1-0.9-0.0-1.3
Time in novel zone, hab. session 20.50.51.21.1-1.11.10.7-0.9-1.0-0.9-0.4-0.60.50.50.6-0.5-0.70.50.90.7-0.7-0.50.60.5-0.10.90.60.10.7
Total zone transitions, hab. session 20.70.94.31.9-1.51.51.8-1.0-1.5-1.0-0.00.10.4-0.10.5-0.1-0.50.10.60.6-0.6-0.30.50.10.32.10.2-0.1-0.6
Total locomotion distance, hab. session 20.50.71.61.3-1.11.21.0-1.0-1.2-1.0-0.4-0.50.80.50.8-0.5-0.80.51.00.9-0.9-0.60.70.4-0.11.20.40.4-0.4
Locomotion velocity, hab. session 20.60.82.71.6-1.31.41.4-1.1-1.4-1.1-0.3-0.40.70.30.7-0.4-0.70.40.90.9-0.9-0.60.70.40.01.60.30.2-0.5
Novel to familiar place preference ratio0.50.71.30.9-1.00.90.8-0.9-0.9-0.9-0.7-1.20.81.20.7-0.8-0.80.80.80.8-0.8-0.80.71.0-0.50.40.80.50.6
Novelty place preference0.70.91.70.9-1.11.10.9-1.0-1.1-1.0-0.8-1.30.91.30.9-0.9-0.90.91.00.9-0.9-0.90.91.2-0.70.40.90.70.5
Time in novel zone, NPP test0.70.91.41.0-1.21.11.0-1.1-1.1-1.1-0.8-1.20.91.20.9-0.9-0.90.91.00.9-0.9-0.90.91.1-0.60.70.80.70.3
Total zone transitions, NPP test1.72.53.51.5-1.51.81.5-1.8-1.9-1.8-1.5-1.41.71.41.8-1.5-1.81.51.91.8-1.8-1.71.81.3-1.30.81.51.40.9
Total locomotion distance, NPP test5.17.110.31.3-1.82.31.1-2.8-2.4-2.7-3.0-3.03.13.03.1-2.9-3.03.03.23.1-3.1-3.03.02.7-2.8-0.12.72.62.1
Locomotion velocity, NPP test4.05.78.11.2-1.62.00.9-2.4-2.1-2.4-2.7-2.82.72.72.7-2.7-2.72.72.82.8-2.8-2.72.72.3-2.6-0.32.52.32.0
Intraocular pressure1.21.92.90.5-0.61.00.5-1.4-1.1-1.3-1.7-1.51.51.51.6-1.6-1.71.61.61.6-1.6-1.61.61.0-1.6-0.31.31.70.6
Delta distance traveled before/after self-admin0.40.51.00.30.6-0.70.40.80.20.71.00.7-0.8-0.7-0.80.90.6-0.9-0.3-0.70.70.8-0.8-0.80.80.2-0.8-0.5-0.9
Delta ambulatory time before/after self-admin0.30.51.10.70.3-0.50.90.6-0.20.61.01.0-0.8-1.0-0.80.90.5-0.9-0.1-0.70.70.7-0.8-0.70.90.5-0.7-0.7-0.6
Parametrial fat weight1.53.66.70.0-0.60.9-0.1-1.6-0.8-1.5-2.5-1.32.21.32.1-2.4-2.12.42.02.1-2.1-2.32.12.2-2.6-1.52.42.02.5
Pavlov. Cond. lever latency0.30.31.4-1.11.2-0.9-1.00.60.90.60.00.4-0.2-0.4-0.20.10.3-0.1-0.5-0.30.30.1-0.2-0.5-0.3-0.8-0.30.4-0.5
Pavlov. Cond. magazine entry latency0.00.00.30.3-0.30.20.2-0.1-0.2-0.1-0.0-0.2-0.10.20.0-0.0-0.00.00.20.1-0.1-0.00.00.20.2-0.20.2-0.20.6
Pavlov. Cond. change in total contacts0.80.84.11.9-1.71.21.9-0.5-1.2-0.60.60.4-0.3-0.4-0.30.50.2-0.50.0-0.10.10.4-0.20.11.22.0-0.3-1.0-0.3
Pavlov. Cond. index score0.20.21.11.1-1.00.71.0-0.3-0.7-0.30.30.0-0.2-0.0-0.10.20.1-0.30.1-0.00.00.2-0.10.10.70.8-0.1-0.70.3
Pavlov. Cond. latency score0.20.31.21.1-1.10.81.0-0.4-0.8-0.40.1-0.2-0.00.20.00.0-0.1-0.10.30.2-0.20.00.00.30.50.70.1-0.50.4
Pavlov. Cond. lever contacts0.20.31.11.0-1.00.80.9-0.5-0.8-0.5-0.0-0.40.10.40.2-0.1-0.20.10.50.2-0.2-0.10.20.40.40.60.3-0.40.6
Pavlov. Cond. magazine entry number0.30.31.1-0.70.5-0.2-0.6-0.20.1-0.2-0.7-0.60.70.60.6-0.7-0.60.70.50.5-0.5-0.70.60.4-1.1-0.60.51.00.0
Pavlov. Cond. intertrial magazine entries1.51.82.91.5-1.51.51.6-1.6-1.7-1.5-1.2-1.31.41.31.3-1.3-1.41.31.41.3-1.3-1.31.41.3-1.00.81.21.00.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.21.1-1.00.61.0-0.2-0.6-0.20.50.2-0.4-0.2-0.30.40.3-0.4-0.0-0.20.20.4-0.30.00.90.9-0.2-0.80.1
Pavlov. Cond. response bias0.30.31.10.6-0.40.10.50.3-0.10.20.70.5-0.7-0.5-0.60.70.6-0.7-0.4-0.60.60.7-0.6-0.41.00.5-0.4-1.00.1
Pavlov. Cond. lever latency0.50.73.8-1.81.4-1.1-1.80.61.10.6-0.4-0.50.20.50.1-0.4-0.00.40.10.1-0.1-0.30.10.1-0.8-1.90.00.80.1
Pavlov. Cond. magazine entry latency0.20.31.41.0-0.90.81.2-0.6-0.9-0.5-0.1-0.30.10.30.2-0.1-0.30.10.30.1-0.1-0.10.20.10.30.70.3-0.20.5
Pavlov. Cond. change in total contacts0.51.23.91.7-1.00.61.80.1-0.70.11.21.2-1.0-1.2-0.91.10.8-1.2-0.9-0.80.81.0-0.8-0.91.62.0-0.8-1.4-0.8
Pavlov. Cond. index score0.40.63.11.7-1.31.01.8-0.5-1.1-0.50.40.4-0.2-0.4-0.20.40.0-0.4-0.1-0.10.10.3-0.1-0.20.91.7-0.1-0.8-0.1
Pavlov. Cond. latency score0.40.63.21.7-1.41.21.8-0.8-1.2-0.70.10.20.1-0.20.10.1-0.2-0.20.10.1-0.10.00.10.00.61.70.1-0.50.1
Pavlov. Cond. lever contacts0.50.73.61.8-1.51.11.8-0.6-1.1-0.60.40.4-0.2-0.4-0.10.40.0-0.4-0.1-0.00.00.3-0.1-0.10.81.9-0.0-0.80.0
Pavlov. Cond. magazine entry number0.30.41.5-1.01.0-0.9-1.20.81.00.80.40.5-0.4-0.5-0.50.40.6-0.4-0.6-0.50.50.4-0.5-0.40.1-0.7-0.5-0.1-0.6
Pavlov. Cond. intertrial magazine entries3.06.511.2-0.5-0.71.2-0.6-2.0-1.1-2.0-3.2-3.13.03.12.8-3.1-2.83.12.82.8-2.8-2.92.83.0-3.3-1.72.72.92.4
Pavlov. Cond. lever-magazine prob. diff.0.40.62.91.6-1.20.91.7-0.4-0.9-0.40.50.5-0.3-0.5-0.30.50.1-0.5-0.2-0.30.30.4-0.2-0.31.01.7-0.2-0.8-0.2
Pavlov. Cond. response bias0.50.74.01.9-1.51.22.0-0.7-1.3-0.70.30.4-0.1-0.4-0.00.3-0.0-0.3-0.00.0-0.00.20.0-0.00.82.00.0-0.70.1
Time in closed arm before self-admin0.20.31.50.00.3-0.4-0.20.50.40.50.8-0.1-0.50.1-0.50.60.4-0.6-0.4-0.50.50.5-0.4-0.50.70.5-0.8-0.2-1.2
Time in closed arm after self-admin0.40.41.10.3-0.20.30.3-0.6-0.7-0.5-0.6-0.90.80.90.7-0.7-0.80.71.00.7-0.7-0.80.60.6-0.70.10.41.0-0.2
Time in open arm before self-admin0.70.91.61.3-1.00.91.1-1.1-1.1-1.1-1.0-0.01.1-0.01.1-1.0-1.01.01.01.1-1.1-1.10.91.0-0.90.31.00.70.5
Time in open arm after self-admin0.00.00.1-0.2-0.00.0-0.1-0.00.1-0.0-0.1-0.10.10.10.1-0.1-0.10.1-0.20.2-0.2-0.10.20.1-0.2-0.1-0.00.3-0.2
Bone: periosteal estimation0.20.51.41.2-1.21.11.0-0.9-0.9-0.9-0.6-0.50.60.40.6-0.6-0.60.60.40.6-0.6-0.60.60.7-0.30.50.70.10.6
Bone: periosteal perimeter0.71.32.31.4-1.51.51.3-1.4-1.5-1.4-1.0-1.01.21.01.2-1.0-1.31.01.21.2-1.2-1.11.21.0-0.70.71.10.70.6
Bone: post-yield work1.32.33.5-1.51.7-1.9-1.51.81.91.81.41.2-1.6-1.1-1.71.31.7-1.3-1.7-1.71.71.5-1.7-1.41.1-1.4-1.3-1.2-0.4
Progressive ratio test 1 active lever presses0.91.62.4-1.51.4-1.5-1.41.51.31.41.11.5-1.3-1.5-1.31.21.3-1.2-1.0-1.31.31.3-1.4-1.31.1-0.7-1.0-1.50.0
Progressive ratio test 1 breakpoint1.01.72.4-1.41.3-1.4-1.31.51.31.41.21.5-1.4-1.5-1.41.31.3-1.3-1.0-1.31.31.4-1.4-1.41.2-0.6-1.0-1.5-0.0
Progressive ratio test 1 inactive lever presses0.20.51.7-0.80.6-0.3-0.7-0.0-0.1-0.0-0.6-1.00.51.10.6-0.7-0.70.71.20.7-0.7-0.70.50.4-0.8-1.30.71.00.7
Progressive ratio test 2 active lever presses0.71.01.7-0.61.0-1.0-0.41.10.81.11.10.7-1.2-0.6-1.21.11.1-1.1-0.9-1.21.21.2-1.3-1.31.3-0.5-0.9-1.30.2
Progressive ratio test 2 breakpoint0.70.91.7-0.40.8-0.8-0.31.00.61.01.00.6-1.2-0.6-1.11.11.1-1.1-0.9-1.11.11.2-1.2-1.21.3-0.4-0.9-1.30.2
Progressive ratio test 2 inactive lever presses0.20.51.8-1.31.4-1.1-1.10.80.80.90.5-0.3-0.70.3-0.60.40.6-0.4-0.4-0.60.60.6-0.7-0.80.3-1.1-0.4-0.30.5
Incentive Sensitization - Responses0.10.32.01.4-0.60.51.4-0.2-0.7-0.20.4-0.2-0.40.2-0.30.40.3-0.4-0.2-0.30.30.4-0.4-0.30.90.5-0.2-0.80.5
Incentive Sensitization - Breakpoint0.10.31.91.4-0.60.61.4-0.3-0.7-0.20.3-0.2-0.30.2-0.20.30.3-0.3-0.2-0.20.20.3-0.3-0.30.80.4-0.1-0.70.7
Sum of active levers in priming session hrs 5-60.30.31.6-1.01.2-1.0-1.00.70.70.70.0-0.3-0.20.3-0.2-0.10.00.1-0.0-0.20.20.1-0.3-0.1-0.3-1.3-0.10.5-0.1
Progressive ratio0.20.61.90.7-0.30.10.70.3-0.20.31.10.6-0.7-0.6-0.70.90.7-0.9-0.5-0.90.90.8-0.7-0.91.40.9-0.9-0.8-1.3
Food seeking constrained by brief footshock2.93.67.6-2.12.8-2.4-2.42.32.32.42.00.9-1.8-0.9-1.71.81.7-1.8-1.6-1.71.71.8-1.8-2.51.2-0.8-2.2-0.3-2.5
Seeking ratio, punishment vs. effort0.40.83.0-1.41.7-1.5-1.51.21.41.20.60.4-0.7-0.4-0.70.60.8-0.6-0.9-0.50.50.6-0.7-1.00.0-0.9-0.80.2-0.6
Retroperitoneal fat weight0.31.22.2-0.1-0.10.3-0.2-0.8-0.5-0.8-1.5-0.81.30.81.2-1.4-1.21.41.31.3-1.3-1.31.11.4-1.5-1.31.21.21.3
Reaction time number correct0.00.10.8-0.40.8-0.5-0.40.50.40.50.3-0.2-0.30.2-0.20.30.2-0.3-0.1-0.10.10.2-0.2-0.40.0-0.4-0.30.3-0.9
Reaction time mean minus median0.10.41.31.0-0.90.81.1-0.7-0.9-0.6-0.2-0.80.40.80.5-0.4-0.50.40.30.5-0.5-0.50.50.4-0.31.00.20.6-0.4
Reaction time mean minus median AUC0.00.20.90.5-0.50.50.6-0.4-0.7-0.3-0.1-0.90.21.00.3-0.2-0.40.20.50.4-0.4-0.30.30.1-0.10.40.00.6-0.3
Reaction time num false alarms0.50.82.01.4-1.11.11.2-1.0-1.2-1.0-0.8-0.50.80.50.9-0.7-0.80.71.00.9-0.9-0.80.90.8-0.70.60.80.50.6
Reaction time num false alarms AUC0.20.42.11.4-1.00.81.3-0.7-1.0-0.7-0.3-0.20.30.20.4-0.3-0.40.30.60.4-0.4-0.40.40.5-0.20.70.5-0.00.6
Reaction time trials correct on left0.00.10.8-0.40.8-0.5-0.40.50.40.50.3-0.2-0.30.2-0.20.30.2-0.3-0.1-0.10.10.2-0.2-0.40.0-0.4-0.30.3-0.9
Reaction time trials on left0.00.10.7-0.40.8-0.5-0.50.50.40.50.2-0.2-0.20.3-0.20.20.1-0.2-0.0-0.10.10.1-0.2-0.4-0.1-0.4-0.30.4-0.8
Reaction time mean0.00.10.6-0.0-0.1-0.10.00.10.00.20.4-0.4-0.30.4-0.30.30.2-0.3-0.3-0.30.30.3-0.2-0.30.20.6-0.60.1-0.8
Reaction time mean AUC0.10.11.00.2-0.40.20.3-0.0-0.20.00.4-0.4-0.20.4-0.20.20.1-0.2-0.2-0.20.20.2-0.1-0.20.31.0-0.50.1-0.9
Median of all reaction times0.20.30.7-0.40.2-0.4-0.30.40.40.50.6-0.1-0.50.1-0.60.50.5-0.5-0.6-0.60.60.6-0.5-0.50.50.5-0.8-0.1-0.8
Reaction time omissions0.81.33.0-0.4-0.20.5-0.3-0.8-0.4-0.8-1.3-1.61.21.61.3-1.4-1.21.41.11.4-1.4-1.41.31.2-1.6-0.71.11.70.5
Reaction time false alarm rate0.20.31.21.1-0.90.70.9-0.6-0.7-0.6-0.4-0.10.30.10.4-0.3-0.30.30.40.3-0.3-0.30.40.5-0.20.50.5-0.10.9
Reaction time premature initiation rate0.40.61.30.20.5-0.40.00.70.50.70.90.7-1.0-0.7-0.81.01.0-1.0-1.0-0.70.70.9-0.8-1.10.90.5-1.0-0.6-1.0
Reaction time premature initiations0.30.92.0-0.20.9-0.8-0.21.00.71.01.10.7-1.1-0.7-1.01.21.1-1.1-1.0-0.80.81.0-1.0-1.30.90.2-1.2-0.5-1.4
Std. dev. reaction times0.00.10.30.1-0.10.00.2-0.0-0.10.10.2-0.5-0.10.5-0.10.10.1-0.1-0.2-0.00.00.1-0.0-0.30.00.6-0.30.3-0.6
Reaction time trials completed0.00.10.7-0.40.8-0.5-0.50.50.40.50.2-0.2-0.20.3-0.20.20.1-0.2-0.0-0.10.10.1-0.2-0.4-0.1-0.4-0.30.4-0.8
Reaction time trials AUC0.00.10.6-0.40.7-0.4-0.40.40.30.40.2-0.3-0.20.3-0.10.10.1-0.10.0-0.10.10.1-0.1-0.3-0.1-0.4-0.20.4-0.8
Run reversals in cocaine runway, females0.20.21.2-0.90.5-0.2-0.6-0.10.3-0.1-0.60.80.3-0.80.3-0.4-0.20.40.10.3-0.3-0.30.2-0.0-0.5-1.10.40.00.8
Run reversals in cocaine runway, males3.53.99.00.50.2-0.60.21.41.01.32.42.3-2.4-2.3-2.22.52.2-2.5-2.4-2.12.12.4-2.1-2.12.71.6-1.7-3.0-0.4
Latency to leave start box in cocaine runway0.40.61.8-0.40.3-0.3-0.10.70.30.61.10.4-0.9-0.3-0.71.10.8-1.0-0.4-0.70.70.9-0.8-1.31.10.7-1.0-0.7-1.2
Latency to leave start box in cocaine runway, F1.31.63.5-0.10.2-0.40.21.10.51.01.80.5-1.5-0.5-1.41.71.5-1.7-1.0-1.41.41.6-1.4-1.81.91.2-1.5-1.4-1.4
Latency to leave start box in cocaine runway, M0.10.10.4-0.20.00.3-0.0-0.2-0.2-0.2-0.3-0.20.30.20.5-0.3-0.40.30.50.6-0.6-0.40.5-0.0-0.3-0.10.10.6-0.4
Std. dev. time between licks in bursts4.99.212.61.9-2.42.91.9-3.3-2.9-3.2-3.4-3.63.53.53.4-3.3-3.33.33.23.4-3.4-3.43.53.0-3.00.22.93.21.2
Total sessions with >9 infusions0.10.21.0-0.80.4-0.5-1.00.50.50.40.20.3-0.2-0.3-0.30.30.2-0.30.0-0.30.30.3-0.3-0.50.1-0.2-0.2-0.3-0.0
Short access day 1 total inactive lever presses1.42.75.6-0.90.6-1.2-1.21.41.51.41.52.2-1.7-2.2-1.91.71.8-1.7-2.0-1.91.91.9-1.8-1.81.70.2-1.4-2.40.1
Short access day 10 total inactive lever presses0.00.10.2-0.1-0.1-0.0-0.3-0.10.1-0.1-0.3-0.20.30.20.2-0.2-0.20.20.10.1-0.1-0.20.20.4-0.4-0.40.30.30.3
Short access day 1 total infusions0.61.12.9-1.30.9-1.2-1.71.21.21.20.91.2-0.9-1.2-1.11.00.9-1.0-0.6-1.11.11.1-1.1-1.30.7-0.1-0.9-1.1-0.3
Short access day 10 total infusions0.30.52.60.5-0.60.30.60.1-0.40.00.51.4-0.5-1.5-0.50.70.5-0.7-0.2-0.40.40.7-0.5-0.61.01.1-0.2-1.60.5
Short access total infusions0.30.51.7-0.30.0-0.4-0.50.50.30.50.61.2-0.7-1.2-0.70.80.6-0.8-0.3-0.70.70.8-0.8-0.90.80.4-0.5-1.30.2
Short access day 1 locomotion0.20.31.70.8-0.90.40.5-0.0-0.4-0.10.40.6-0.3-0.6-0.40.60.2-0.6-0.0-0.30.30.5-0.4-0.40.91.3-0.1-1.20.2
Short access day 10 total locomotion0.00.10.60.3-0.80.3-0.0-0.4-0.3-0.3-0.3-0.40.40.40.2-0.3-0.30.30.50.3-0.3-0.20.20.5-0.20.40.10.10.1
Short access total locomotion0.10.11.00.7-1.00.60.3-0.3-0.4-0.30.00.20.1-0.2-0.00.1-0.1-0.10.10.1-0.10.1-0.00.10.31.00.0-0.60.2
One hour access (0.3 mA shock)0.20.22.8-0.30.1-0.2-0.40.10.20.0-0.30.90.1-0.9-0.1-0.0-0.00.0-0.1-0.10.10.1-0.1-0.30.1-0.50.5-0.91.7
Compulsive drug intake1.21.83.4-0.2-0.91.1-0.3-1.3-0.7-1.3-1.7-0.81.60.81.6-1.6-1.61.61.31.6-1.6-1.61.51.4-1.6-0.11.90.91.8
One hour access (shock baseline)0.20.40.9-0.40.8-0.8-0.40.70.50.70.50.9-0.6-0.9-0.70.70.6-0.7-0.5-0.70.70.7-0.7-1.00.5-0.3-0.6-0.80.0
Social response proportion0.81.03.8-1.61.9-1.5-1.91.21.51.30.7-0.8-0.60.8-0.50.40.6-0.4-0.4-0.40.40.4-0.7-0.80.1-1.7-0.80.8-0.9
Social responses2.63.58.60.00.30.6-0.2-1.2-0.8-1.1-2.0-2.61.92.62.1-2.2-2.12.22.32.1-2.1-2.12.01.6-2.3-2.11.62.91.0
Social time1.01.62.31.2-1.51.51.0-1.4-1.5-1.4-1.2-1.51.31.51.3-1.2-1.41.21.51.2-1.2-1.31.31.5-0.90.41.21.01.1
Soleus weight0.61.83.0-0.50.9-1.0-0.71.31.11.21.51.7-1.4-1.7-1.41.51.4-1.5-1.4-1.41.41.4-1.4-1.71.30.8-1.2-1.3-1.3
Bone: stiffness0.20.30.70.4-0.30.00.50.30.10.30.70.8-0.6-0.8-0.60.70.6-0.7-0.8-0.60.60.6-0.6-0.40.70.6-0.5-0.8-0.5
Tibialis anterior weight3.211.024.11.6-0.2-0.61.52.00.81.94.14.9-3.4-4.9-3.44.03.3-4.0-3.4-3.23.23.7-3.2-3.54.44.1-3.2-4.1-3.4
Time to tail flick, vehicle, before self-admin0.10.11.0-0.2-0.00.1-0.7-0.20.1-0.2-0.4-0.30.30.30.3-0.4-0.30.40.30.3-0.3-0.30.20.4-0.3-0.40.50.11.0
Time to tail flick, vehicle, after self-admin1.63.29.5-1.31.6-1.6-1.02.01.91.92.11.0-1.9-0.9-1.81.91.9-1.9-2.3-2.02.01.8-1.9-1.91.40.3-2.2-0.7-3.1
Time to tail flick, test, before self-admin1.61.84.60.5-0.40.70.2-1.2-0.7-1.2-1.9-0.61.50.61.5-1.7-1.51.71.31.5-1.5-1.61.71.5-1.7-1.31.61.22.1
Time to tail flick, test, after self-admin1.51.68.2-1.71.7-1.3-1.90.20.90.4-1.1-1.30.71.30.9-1.2-0.81.20.70.8-0.8-1.00.70.7-1.7-2.90.62.10.1
Delta time to tail flick, vehicle, before/after SA2.12.35.1-1.51.8-1.8-1.01.81.81.91.60.5-1.6-0.4-1.51.41.6-1.4-1.9-1.61.61.4-1.6-1.40.8-0.9-1.8-0.2-2.3
Delta time to tail flick, test, before/after SA1.31.65.4-2.32.2-2.0-2.31.51.81.60.7-0.6-0.80.7-0.60.50.7-0.5-0.7-0.80.80.6-0.9-0.8-0.2-1.8-0.90.8-1.6
Tibia length2.77.612.73.0-3.63.43.0-3.3-3.3-3.3-2.7-2.42.82.32.7-2.6-2.82.62.62.8-2.8-2.62.83.1-1.91.12.71.42.5
Ambulatory time before self-admin0.10.41.60.8-0.90.60.9-0.2-0.4-0.20.40.8-0.3-0.8-0.40.50.3-0.5-0.5-0.30.30.4-0.4-0.10.81.3-0.3-1.1-0.1
Ambulatory time after self-admin1.21.94.71.8-0.70.12.20.4-0.70.41.51.9-1.2-1.9-1.21.61.0-1.6-0.9-1.11.11.3-1.3-1.01.92.0-1.3-1.8-1.0
Bone: tissue strength0.30.30.70.8-0.90.70.7-0.7-0.6-0.7-0.5-0.60.50.60.5-0.6-0.50.60.40.5-0.5-0.60.50.7-0.50.30.60.30.6
Total heroin consumption1.51.84.50.4-0.4-0.10.20.90.60.81.61.3-1.4-1.3-1.51.61.5-1.6-1.6-1.51.51.6-1.5-1.02.01.5-1.3-2.1-1.0
Bone: trabecular number1.32.44.3-0.0-0.50.8-0.0-1.3-0.8-1.3-1.9-2.11.72.11.7-1.9-1.71.91.71.7-1.7-1.81.71.6-1.9-1.21.61.91.4
Bone: trabecular spacing1.21.73.30.10.3-0.60.21.00.51.01.61.8-1.5-1.8-1.41.61.4-1.6-1.3-1.41.41.5-1.3-1.61.61.3-1.4-1.5-1.3
Bone: trabecular thickness0.50.71.40.8-0.90.90.8-0.9-0.9-0.9-0.8-1.10.91.10.8-0.9-0.90.90.80.8-0.8-0.90.81.2-0.6-0.20.80.60.8
Bone: trabecular tissue density0.50.81.50.4-0.3-0.10.50.50.20.51.11.1-0.9-1.1-1.01.01.0-1.1-1.1-1.01.01.0-1.0-0.71.21.2-1.0-1.2-1.0
Water consumed over 24 hours0.30.61.50.7-0.40.20.70.3-0.10.20.81.0-0.7-1.0-0.70.90.6-0.9-0.6-0.60.60.8-0.6-0.71.20.9-0.8-1.0-0.9
Number of responses in last shaping day0.60.81.90.6-0.1-0.00.70.5-0.20.51.11.1-1.0-1.1-1.01.00.7-1.1-0.6-0.90.91.0-0.9-1.11.41.1-0.8-1.3-0.5