Hub : Genes

Clu

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Clu 0.27 0.13 1.7e-10 0.19 0.16 0.16 0.17 3.7e-10 9.2e-09 5.9e-09 1.6e-09
2 IC gene expression Clu 0.3 0.12 8.3e-11 0.19 0.22 0.21 0.22 2.1e-08 1.2e-09 2.2e-09 1.1e-09
3 pVTA gene expression Clu 0.04 0.03 6.1e-03 0 0.01 0.01 0.01 1.4e-01 6.1e-02 2.8e-02 2.8e-02
4 NAcc gene expression Clu 0.18 0.08 0.0e+00 0.16 0.13 0.18 0.17 3.0e-24 3.6e-19 3.5e-26 1.2e-25
5 OFC gene expression Clu 0.39 0.18 6.6e-05 0.12 0.12 0.11 0.12 9.0e-04 9.9e-04 1.6e-03 1.1e-03
6 LHb mRNA stability Clu 0.58 0.15 3.9e-11 0.26 0.32 0.29 0.3 7.5e-07 2.7e-08 1.1e-07 5.8e-08
7 Brain gene expression Clu 0.29 0.1 0.0e+00 0.23 0.33 0.32 0.33 7.2e-21 1.2e-31 2.7e-30 9.7e-32
8 PL gene expression Clu 0.2 0.09 0.0e+00 0.22 0.23 0.22 0.06 1.3e-23 2.7e-24 4.8e-24 2.1e-07
9 Liver gene expression Clu 0.29 0.15 0.0e+00 0.21 0.24 0.25 0.24 2.6e-23 7.0e-27 4.4e-27 2.2e-26
10 Adipose isoform ratio NM_053021.3 0.04 0.04 3.3e-04 0.02 0.03 0.03 0.03 1.9e-03 2.7e-04 8.4e-04 1.3e-04
11 PL mRNA stability Clu 0.53 0.1 0.0e+00 0.62 0.63 0.63 0.58 4.6e-87 6.9e-89 1.0e-89 8.5e-77
12 Adipose isoform ratio XM_006252094.5 0.04 0.03 7.2e-04 0.02 0.03 0.02 0.03 3.2e-03 5.4e-04 1.4e-03 2.4e-04
13 pVTA mRNA stability Clu 0.52 0.11 0.0e+00 0.41 0.25 0.43 0.19 5.1e-35 4.5e-20 5.3e-37 5.4e-15
14 RMTg alternative TSS NM_053021.3 0.13 0.09 5.5e-03 0.06 0.07 0.04 0.06 1.1e-02 5.4e-03 3.5e-02 1.0e-02
15 BLA mRNA stability Clu 0.48 0.12 0.0e+00 0.32 0.31 0.31 0.32 1.9e-17 4.2e-17 4.8e-17 1.6e-17
16 RMTg alternative TSS XM_006252094.5 0.15 0.09 3.5e-03 0.07 0.09 0.05 0.07 8.0e-03 2.9e-03 1.9e-02 7.1e-03
17 IC mRNA stability Clu 0.54 0.14 0.0e+00 0.44 0.28 0.37 0.05 3.4e-20 2.4e-12 2.6e-16 2.9e-03
18 NAcc isoform ratio NM_053021.3 0.02 0.02 4.9e-03 0 0 0 0 8.3e-02 2.0e-01 2.2e-01 3.1e-01
19 NAcc isoform ratio XM_006252094.5 0.03 0.04 5.7e-03 0 0 0 -0 8.7e-02 2.9e-01 2.9e-01 5.9e-01
20 Brain mRNA stability Clu 0.49 0.1 0.0e+00 0.63 0.64 0.63 0.63 6.2e-75 2.6e-76 7.3e-76 3.6e-76
21 NAcc mRNA stability Clu 0.32 0.09 0.0e+00 0.41 0.1 0.4 0.03 1.7e-67 4.8e-15 3.7e-64 1.6e-05
22 IC intron excision ratio chr15_44366276_44367860 0.11 0.07 2.4e-04 0.07 0.05 0.06 0.05 7.3e-04 2.6e-03 2.2e-03 4.9e-03
23 OFC mRNA stability Clu 0.66 0.14 4.6e-12 0.24 0.24 0.25 0.27 2.0e-06 1.8e-06 1.1e-06 4.3e-07
24 IL mRNA stability Clu 0.81 0.11 1.1e-16 0.41 0.33 0.41 0.3 7.7e-11 1.3e-08 5.4e-11 6.8e-08
25 Adipose gene expression Clu 0.75 0.11 0.0e+00 0.16 0.23 0.22 0.23 2.4e-17 1.9e-25 1.8e-24 2.2e-25
26 Adipose mRNA stability Clu 0.04 0.04 4.4e-04 0.01 0.02 0.02 0.02 8.3e-03 3.3e-03 1.6e-03 5.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.11.93.7-0.2-0.50.2-0.9-0.2-1.2-0.8-1.21.7-1.9-1.61.9-1.6-1.7-1.61.7-1.5-1.61.6-1.6-1.5-1.4-1.7-1.51.7-1.1
Area under the delay curve0.40.42.3-1.1-0.4-0.6-0.2-1.1-0.1-0.4-0.1-0.21.50.3-1.50.40.30.4-0.30.50.3-0.30.30.40.00.80.1-1.1-0.4
BMI with tail0.20.71.00.90.80.40.80.80.90.90.9-1.00.51.0-0.50.90.90.9-0.90.90.9-0.90.90.91.00.80.8-0.60.7
BMI without tail0.51.63.51.91.81.51.71.71.51.71.6-1.10.61.3-0.61.21.01.3-1.01.21.2-1.21.11.21.30.61.0-0.50.3
Body weight0.10.31.4-0.9-0.7-1.2-0.6-1.0-0.1-0.5-0.1-0.60.30.5-0.30.40.50.3-0.50.30.3-0.30.50.40.40.90.3-0.9-0.0
Weight adjusted by age0.50.84.4-2.1-1.5-2.0-1.2-2.1-0.7-1.1-0.7-0.3-0.50.00.5-0.10.20.0-0.20.2-0.20.20.0-0.1-0.10.60.2-0.11.3
Bone surface1.32.43.9-1.0-1.3-0.7-1.5-0.8-1.6-1.3-1.61.7-2.0-1.72.0-1.7-1.7-1.71.7-1.6-1.71.7-1.7-1.7-1.6-1.5-1.61.5-1.1
Bone volume1.32.44.2-0.8-1.2-0.6-1.4-0.8-1.6-1.3-1.51.7-2.1-1.72.1-1.7-1.7-1.71.7-1.6-1.71.7-1.7-1.6-1.6-1.5-1.51.6-0.9
Breakpoint value in progressive ratio session0.10.10.5-0.1-0.2-0.2-0.3-0.2-0.20.0-0.20.10.7-0.2-0.7-0.1-0.1-0.10.10.3-0.20.2-0.1-0.2-0.2-0.2-0.1-0.10.3
Number of licking bursts0.20.31.00.90.91.00.81.00.60.80.6-0.10.20.3-0.10.30.20.4-0.20.30.4-0.40.30.40.4-0.00.30.00.3
Context. condit. distance diff. score3.13.712.63.53.33.53.03.52.32.92.3-0.80.81.3-0.81.30.91.3-0.91.31.3-1.31.11.41.60.11.2-0.20.2
Locomotion velocity, session 10.80.81.2-0.9-0.8-0.8-1.0-0.9-1.0-1.1-1.00.8-0.8-1.00.8-1.0-0.8-1.00.8-1.1-1.11.1-1.0-1.0-0.8-0.8-0.61.00.3
Locomotion distance, session 12.53.25.3-2.2-2.1-2.1-2.3-2.1-2.1-2.3-2.11.5-1.1-1.81.1-1.9-1.5-1.91.5-1.9-1.91.9-1.7-1.9-1.4-1.2-1.51.2-0.7
Locomotion velocity, session 21.21.42.7-1.6-1.5-1.5-1.6-1.4-1.4-1.5-1.40.9-0.9-1.20.8-1.2-0.9-1.20.9-1.2-1.31.3-1.1-1.2-0.9-0.7-0.90.8-0.1
Locomotion distance, session 23.65.08.2-2.6-2.5-2.4-2.8-2.6-2.6-2.9-2.61.9-1.8-2.21.8-2.3-1.9-2.31.9-2.5-2.52.5-2.2-2.4-1.8-1.6-2.01.6-0.8
Locomotion velocity, session 31.71.92.80.61.20.71.20.51.51.01.5-1.61.51.6-1.51.51.61.5-1.61.31.4-1.41.61.51.71.41.5-1.21.3
Locomotion distance, session 30.80.81.50.81.21.11.10.71.01.01.1-0.80.91.0-0.90.90.81.0-0.81.00.9-0.90.90.81.10.60.8-0.40.7
Stereotopy head waving bouts, day 30.10.10.5-0.6-0.4-0.7-0.4-0.4-0.2-0.4-0.2-0.20.2-0.0-0.2-0.00.2-0.1-0.2-0.2-0.10.10.10.10.10.20.2-0.10.5
Stereotopy head waving duration, day 30.60.71.5-0.8-0.4-1.1-0.2-0.60.3-0.20.3-1.11.10.8-1.10.81.10.6-1.10.50.7-0.70.90.90.81.20.9-1.10.9
Locomotion velocity, session 73.03.314.03.73.23.72.93.72.02.82.1-0.20.10.9-0.10.90.30.9-0.30.91.1-1.10.71.00.8-0.50.50.2-0.6
Locomotion distance, session 71.62.110.63.12.43.32.02.81.01.81.00.8-1.1-0.21.1-0.1-0.7-0.10.8-0.10.1-0.1-0.4-0.1-0.2-1.6-0.51.2-1.2
Stereotopy head waving bouts, day 70.40.52.0-1.2-0.9-1.4-0.7-1.1-0.2-0.7-0.2-0.70.80.4-0.80.40.70.3-0.70.10.3-0.30.50.40.41.10.5-0.80.7
Stereotopy head waving duration, day 71.11.33.2-1.0-0.4-1.2-0.1-0.80.5-0.10.5-1.41.61.2-1.61.11.41.0-1.40.91.0-1.01.31.11.21.81.2-1.41.3
Locomotion velocity, session 80.50.61.00.81.00.70.80.80.90.80.8-0.70.90.7-0.80.60.70.7-0.70.60.6-0.60.70.71.00.60.9-0.40.9
Locomotion distance, session 80.20.30.80.80.80.90.30.8-0.00.2-0.00.6-0.4-0.40.4-0.5-0.5-0.50.5-0.6-0.60.6-0.5-0.50.2-0.8-0.40.8-0.5
Degree of sensitization distance2.02.05.42.31.32.31.02.20.10.90.11.5-1.9-1.11.9-0.9-1.5-1.01.5-0.9-0.70.7-1.2-0.8-1.1-2.1-1.21.6-1.9
Degree of sensitization stereotypy0.60.71.8-0.7-0.4-0.9-0.1-0.60.3-0.10.3-1.01.20.8-1.20.81.00.7-1.00.60.7-0.70.90.80.71.30.8-1.10.7
Conditioned locomotion0.30.41.71.31.21.21.01.10.70.80.7-0.10.10.2-0.10.20.10.2-0.10.20.2-0.20.10.20.5-0.40.30.50.4
Cocaine response after cond. corrected1.92.24.82.02.22.02.12.01.82.01.8-1.20.91.3-0.91.31.11.4-1.11.41.3-1.31.21.41.30.71.4-0.41.5
Cocaine response after cond. not corrected0.91.12.71.51.61.51.41.71.21.51.2-0.70.60.8-0.60.80.70.9-0.70.90.8-0.80.70.81.00.30.8-0.11.0
Cocaine response before conditioning2.12.53.6-1.5-1.8-1.6-1.9-1.5-1.9-1.8-1.91.5-1.3-1.61.2-1.6-1.5-1.61.5-1.6-1.61.6-1.5-1.6-1.5-1.2-1.60.9-1.5
Saline control response1.21.63.0-1.6-1.7-1.5-1.6-1.7-1.4-1.7-1.40.9-1.0-1.11.0-1.1-1.0-1.21.0-1.3-1.21.2-1.0-1.1-1.4-0.6-1.10.6-0.9
Bone: connectivity density1.82.85.50.40.00.9-0.60.5-1.2-0.6-1.22.1-2.3-1.92.3-1.9-2.0-1.82.0-1.9-1.91.9-2.0-1.8-1.5-2.2-1.72.3-1.2
Bone: cortical apparent density1.11.52.81.31.41.41.71.31.61.51.6-1.20.61.3-0.61.41.11.3-1.11.11.4-1.41.21.41.01.01.2-0.80.4
Bone: cortical area0.20.31.2-1.1-1.1-1.1-0.9-0.9-0.6-0.7-0.60.2-0.1-0.30.1-0.2-0.2-0.30.2-0.2-0.30.3-0.2-0.3-0.40.2-0.4-0.4-0.5
Bone: cortical porosity0.30.41.9-1.4-1.0-1.3-0.9-1.2-0.5-0.8-0.5-0.20.5-0.0-0.5-0.10.2-0.0-0.20.0-0.10.10.1-0.1-0.10.50.0-0.50.3
Bone: cortical porosity0.50.63.1-1.8-1.4-1.7-1.2-1.5-0.7-1.0-0.7-0.20.4-0.1-0.4-0.10.2-0.1-0.2-0.1-0.20.20.0-0.2-0.30.6-0.1-0.60.1
Bone: cortical thickness0.10.20.7-0.5-0.4-0.5-0.2-0.40.1-0.00.1-0.40.50.4-0.50.40.40.4-0.40.50.4-0.40.40.40.10.70.3-0.8-0.1
Bone: cortical thickness0.81.01.51.11.21.11.11.11.21.21.2-0.90.81.0-0.81.00.91.0-0.91.01.0-1.01.01.01.00.80.8-0.80.5
Bone: cortical tissue density1.41.83.31.51.61.51.81.41.71.61.7-1.30.71.4-0.61.51.21.4-1.21.21.5-1.51.31.51.21.11.3-0.90.5
Condit. Reinf. active minus inactive responses0.30.31.4-1.1-1.0-1.2-0.9-1.0-0.7-1.0-0.70.2-0.3-0.30.3-0.3-0.2-0.40.2-0.6-0.40.4-0.3-0.4-0.30.1-0.2-0.00.1
Condit. Reinf. active-inactive response ratio0.30.31.10.10.3-0.10.30.30.40.30.4-0.60.70.5-0.70.50.70.5-0.70.30.5-0.50.60.50.80.60.7-0.51.0
Condit. Reinf. active responses1.41.73.1-1.7-1.8-1.6-1.7-1.6-1.6-1.8-1.51.1-1.2-1.21.2-1.2-1.1-1.31.1-1.4-1.31.3-1.2-1.2-1.3-0.6-1.00.7-0.6
Condit. Reinf. inactive responses3.94.86.1-2.0-2.3-1.6-2.3-2.0-2.5-2.4-2.42.2-2.3-2.22.3-2.2-2.2-2.22.2-2.2-2.32.3-2.2-2.2-2.5-1.7-2.11.6-1.9
Incentive salience index mean0.81.03.9-1.9-1.8-2.0-1.6-1.8-1.2-1.6-1.20.3-0.5-0.50.5-0.6-0.4-0.60.3-0.9-0.60.6-0.5-0.6-0.70.2-0.4-0.00.1
Condit. Reinf. lever presses1.42.05.7-2.3-2.4-2.3-2.1-2.2-1.7-2.1-1.70.7-1.0-1.11.0-1.1-0.8-1.10.8-1.3-1.11.1-0.9-1.1-1.3-0.1-0.80.2-0.2
Condit. Reinf. active minus inactive responses0.50.61.0-0.3-0.6-0.3-0.7-0.4-0.8-0.6-0.91.0-0.5-1.00.5-0.9-0.9-0.90.9-0.7-1.01.0-0.9-1.0-0.9-1.0-0.80.8-0.6
Condit. Reinf. active-inactive response ratio0.20.20.70.50.40.30.40.40.50.50.4-0.40.80.4-0.80.40.50.5-0.50.50.4-0.40.40.40.40.20.3-0.40.1
Condit. Reinf. active responses0.81.11.7-0.4-0.6-0.1-0.8-0.5-1.0-0.7-1.01.3-1.0-1.21.0-1.2-1.2-1.11.2-1.0-1.21.2-1.2-1.2-1.2-1.3-1.11.1-1.0
Condit. Reinf. inactive responses1.92.54.3-0.4-0.7-0.0-1.0-0.4-1.5-1.1-1.41.9-2.1-1.82.1-1.7-1.9-1.71.9-1.7-1.71.7-1.8-1.8-1.7-1.9-1.51.8-1.3
Condit. Reinf. lever presses0.70.92.0-1.4-1.4-1.3-1.3-1.4-1.1-1.3-1.10.7-0.6-0.80.6-0.8-0.7-0.90.7-0.8-0.80.8-0.7-0.8-0.9-0.4-0.90.2-0.9
Condit. Reinf. lever reinforcers received0.50.71.1-0.4-0.6-0.2-0.7-0.5-0.9-0.6-0.91.1-0.7-1.00.6-1.0-1.0-0.91.0-0.7-1.01.0-1.0-1.0-0.9-1.0-0.90.8-1.0
Conditioned reinforcement - actives0.20.42.11.30.81.00.61.50.20.60.20.5-0.2-0.40.1-0.3-0.5-0.30.5-0.4-0.20.2-0.3-0.2-0.2-0.8-0.40.4-0.7
Conditioned reinforcement - inactives0.91.32.30.4-0.30.1-0.50.5-1.0-0.6-0.91.4-1.5-1.31.5-1.2-1.3-1.41.3-1.3-1.11.1-1.2-1.1-1.2-1.3-1.31.0-1.5
Conditioned locomotion0.81.12.91.41.21.21.21.71.11.51.0-0.61.20.8-1.20.90.80.9-0.81.10.9-0.90.90.90.90.50.6-1.1-0.2
Patch foraging indifference point 0 sec5.09.213.0-3.1-3.5-2.8-3.6-3.0-3.6-3.5-3.63.1-1.8-3.11.8-3.2-2.9-3.12.9-3.0-3.13.1-3.0-3.2-3.2-2.5-3.31.7-3.1
Patch foraging indifference point AUC2.84.15.21.92.11.62.31.72.22.22.2-1.92.12.1-2.12.22.12.1-2.02.12.3-2.32.12.22.11.62.0-1.71.1
Delay disc. indifference point, 0s delay2.32.64.1-1.9-1.7-1.3-1.8-1.9-1.9-2.0-1.91.7-0.9-1.80.9-1.7-1.6-1.71.6-1.7-1.71.7-1.6-1.7-1.7-1.1-1.60.9-1.1
Delay disc. indifference point, 16s delay0.40.42.6-0.30.50.40.6-0.20.40.20.4-0.31.60.6-1.60.60.40.5-0.40.60.6-0.60.50.50.40.50.0-0.9-0.9
Delay disc. indifference point, 2s delay1.31.54.8-2.2-1.7-1.9-1.7-2.2-1.5-1.9-1.60.90.3-1.1-0.3-1.0-0.7-1.00.7-1.1-1.01.0-0.9-1.0-0.9-0.2-0.8-0.1-0.1
Delay disc. indifference point, 24s delay0.60.74.3-0.00.50.20.6-0.10.60.10.5-0.62.00.5-2.10.70.70.6-0.70.30.8-0.80.70.80.50.90.3-1.4-0.4
Delay disc. indifference point, 4s delay0.91.02.5-0.9-0.1-0.60.2-1.00.60.00.6-1.21.11.1-1.11.11.11.0-1.11.11.1-1.11.11.10.81.61.0-1.40.9
Delay disc. indifference point, 8s delay0.40.41.5-0.5-0.0-0.00.3-0.30.30.40.4-0.41.20.7-1.20.70.50.8-0.51.10.6-0.60.60.60.20.80.4-1.1-0.3
Indifference point function ln k1.22.14.2-2.1-1.6-1.3-1.7-1.8-1.6-1.8-1.61.2-1.5-1.31.4-1.5-1.3-1.31.3-1.4-1.61.6-1.4-1.4-1.3-0.8-1.31.0-0.8
Indifference point function log k1.22.14.2-2.1-1.6-1.3-1.7-1.8-1.6-1.8-1.61.2-1.5-1.31.4-1.5-1.3-1.31.3-1.4-1.61.6-1.4-1.4-1.3-0.8-1.31.0-0.8
Patch foraging total patch changes 0 sec4.48.212.6-3.2-3.5-3.0-3.6-3.2-3.4-3.4-3.42.8-1.7-2.81.6-2.9-2.6-2.92.6-2.8-2.82.8-2.7-2.9-3.0-2.1-3.11.3-2.9
Patch foraging total patch changes 12 sec0.81.01.7-1.1-1.3-1.1-1.2-1.2-1.3-1.2-1.31.10.1-1.1-0.1-0.9-0.9-1.00.9-0.8-0.80.8-0.9-1.0-1.1-0.8-1.20.1-1.3
Patch foraging total patch changes 18 sec0.10.21.3-0.1-0.2-0.0-0.3-0.3-0.5-0.4-0.50.70.2-0.4-0.2-0.4-0.5-0.40.5-0.3-0.30.3-0.4-0.4-0.4-0.4-0.6-0.1-1.1
Patch foraging total patch changes 24 sec0.91.63.8-1.8-1.9-1.9-1.9-1.6-1.6-1.5-1.71.20.1-1.1-0.1-1.1-0.9-1.10.9-0.8-1.01.0-1.0-1.1-1.1-0.5-1.4-0.2-1.4
Patch foraging total patch changes 6 sec0.20.30.9-0.3-0.7-0.5-0.6-0.3-0.7-0.5-0.70.7-0.1-0.60.0-0.5-0.5-0.60.5-0.4-0.40.4-0.5-0.5-0.8-0.6-0.7-0.0-1.0
Patch foraging time to switch 0 sec0.51.01.70.1-0.40.2-0.50.1-0.8-0.5-0.81.2-1.1-1.31.1-1.1-1.2-1.11.2-1.1-1.11.1-1.2-1.1-1.3-1.3-1.01.3-0.2
Patch foraging water rate 0 sec0.10.31.2-1.1-0.6-1.0-0.6-1.1-0.2-0.7-0.2-0.30.40.2-0.40.10.40.1-0.4-0.0-0.00.00.30.10.40.60.1-0.6-0.1
Patch foraging water rate 12 sec0.20.42.4-1.4-1.0-1.3-1.0-1.5-0.6-1.1-0.6-0.0-0.5-0.10.5-0.2-0.0-0.20.0-0.4-0.40.4-0.1-0.2-0.20.4-0.1-0.10.2
Patch foraging water rate 18 sec1.82.86.0-0.80.2-0.80.6-0.71.30.51.3-2.21.52.1-1.42.02.11.9-2.11.81.8-1.82.11.91.92.41.7-2.21.2
Patch foraging water rate 24 sec0.70.91.80.51.10.71.00.21.10.71.2-1.20.31.3-0.21.11.01.1-1.00.91.1-1.11.11.01.31.11.1-0.60.9
Patch foraging water rate 6 sec0.71.04.5-2.0-1.0-1.8-0.9-2.1-0.2-1.1-0.3-0.90.80.6-0.80.60.90.4-0.90.30.4-0.40.70.50.61.60.7-1.30.4
Seeking ratio, delayed vs. immediate footshock2.22.63.7-0.8-1.7-1.4-1.8-0.5-1.8-1.5-1.81.7-1.8-1.81.7-1.8-1.6-1.91.6-1.9-1.91.9-1.7-1.7-1.5-1.3-1.51.3-1.0
Distance traveled before self-admin0.40.52.5-1.2-1.1-1.6-0.8-1.3-0.3-0.7-0.3-0.50.60.2-0.60.30.50.3-0.50.40.3-0.30.40.40.20.90.4-0.90.6
Distance traveled after self-admin0.80.92.9-1.5-0.6-1.1-0.2-1.70.2-0.60.2-1.01.50.8-1.50.81.00.6-1.00.50.6-0.60.80.80.71.30.9-1.30.7
Extensor digitorum longus weight5.019.741.7-1.40.5-2.21.4-1.33.11.63.0-5.66.54.8-6.54.75.54.6-5.54.74.6-4.65.04.64.95.84.6-5.34.8
Bone: elastic displacement1.82.13.4-1.7-1.8-1.6-1.8-1.6-1.7-1.8-1.71.3-1.2-1.51.2-1.4-1.3-1.61.2-1.5-1.41.4-1.4-1.5-1.2-0.9-1.30.9-0.8
Bone: elastic work2.83.77.6-2.8-2.7-2.6-2.7-2.6-2.4-2.6-2.41.5-1.3-1.71.3-1.8-1.5-1.91.5-1.7-1.81.8-1.6-1.8-1.6-0.8-1.60.8-0.9
Bone: endosteal estimation0.30.71.1-0.9-1.0-0.8-1.0-1.0-1.0-0.9-0.90.8-0.8-0.80.7-0.8-0.8-0.80.8-0.6-0.80.8-0.8-0.8-0.8-0.6-0.80.5-0.5
Bone: endosteal perimeter1.22.53.7-1.6-1.8-1.5-1.9-1.5-1.9-1.8-1.91.6-1.4-1.71.4-1.7-1.5-1.71.5-1.6-1.71.7-1.6-1.7-1.4-1.3-1.51.1-0.9
Epididymis fat weight0.10.51.1-0.3-0.10.2-0.3-0.4-0.6-0.6-0.60.9-0.6-0.70.6-0.7-0.9-0.80.9-0.8-0.80.8-0.9-0.7-0.8-0.8-0.80.8-1.1
Delta time in closed arm before/after self-admin0.80.81.70.20.00.4-0.30.1-0.7-0.4-0.61.2-1.0-1.01.0-1.0-1.1-0.91.1-0.9-1.01.0-1.0-1.0-0.6-1.3-0.91.3-0.9
Delta time in open arm before/after self-admin0.10.10.30.60.0-0.10.10.30.30.40.2-0.30.10.3-0.10.40.40.3-0.40.50.3-0.30.40.20.20.30.3-0.30.4
Diff in mean of infusions in LGA sessions0.50.63.0-1.7-1.0-1.1-0.9-1.5-0.7-1.1-0.7-0.0-1.0-0.41.0-0.3-0.2-0.50.2-0.5-0.50.5-0.3-0.3-0.40.20.00.50.8
Delay discount exponential model param0.70.83.41.10.30.7-0.01.1-0.20.2-0.20.6-1.8-0.71.8-0.8-0.7-0.80.7-0.9-0.70.7-0.7-0.8-0.4-1.2-0.41.60.1
Extinction: sum of active levers before priming0.60.61.7-0.7-0.5-0.1-0.6-0.5-0.7-0.7-0.71.0-0.7-0.70.6-0.8-0.9-0.90.9-0.8-0.80.8-0.9-0.8-0.8-0.8-1.00.6-1.3
Active lever presses in extinction session 60.70.71.81.11.31.31.21.11.11.01.1-0.50.50.8-0.40.70.60.7-0.60.60.7-0.70.70.90.60.20.5-0.4-0.0
Bone: final force0.10.20.9-0.9-0.9-0.9-0.7-0.9-0.4-0.5-0.50.10.0-0.2-0.0-0.1-0.1-0.10.10.1-0.10.1-0.1-0.2-0.50.1-0.2-0.3-0.1
Bone: final moment0.30.62.0-1.4-1.4-1.3-1.1-1.4-0.8-0.9-0.90.3-0.3-0.50.3-0.4-0.4-0.40.4-0.2-0.40.4-0.4-0.5-0.90.0-0.4-0.1-0.3
Food consumed during 24 hour testing period0.20.31.2-1.0-1.0-1.0-0.7-1.1-0.3-0.7-0.3-0.20.00.2-0.00.10.2-0.0-0.2-0.10.1-0.10.20.1-0.10.8-0.1-0.8-0.9
Glucose1.42.33.61.21.41.11.61.11.71.71.7-1.41.31.8-1.21.71.51.8-1.51.91.7-1.71.61.71.61.41.2-1.50.3
Heart weight0.30.51.40.2-0.10.4-0.10.3-0.4-0.2-0.40.8-1.2-0.71.2-0.6-0.8-0.70.8-0.8-0.70.7-0.7-0.7-0.9-0.8-0.41.1-0.4
Delay discount hyperbolic model param0.60.72.61.30.50.80.21.3-0.10.4-0.00.5-1.6-0.61.6-0.6-0.6-0.60.6-0.7-0.60.6-0.6-0.6-0.4-1.1-0.41.4-0.0
Intermittent access intake day 1-15 change0.10.30.70.00.30.80.1-0.2-0.3-0.3-0.30.7-0.5-0.70.5-0.6-0.7-0.70.7-0.6-0.40.4-0.7-0.6-0.5-0.7-0.50.9-0.6
Intermittent access intake escalation0.10.20.7-0.10.30.70.1-0.3-0.3-0.2-0.30.6-0.5-0.60.5-0.5-0.6-0.60.6-0.4-0.20.2-0.6-0.6-0.4-0.6-0.40.8-0.4
Intermittent access intake escalation 20.10.10.6-0.20.40.80.4-0.20.1-0.00.10.1-0.4-0.10.4-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.20.10.60.1
Intermitt. access day 1 inactive lever presses0.20.73.61.00.40.90.41.60.00.60.00.5-1.9-0.71.9-0.5-0.6-0.60.6-0.5-0.40.4-0.6-0.5-0.6-1.0-0.31.40.3
Intermitt. access day 15 inactive lever presses0.61.11.70.91.31.01.20.91.21.11.3-1.2-0.81.20.91.11.11.0-1.11.21.1-1.11.11.11.10.91.3-0.20.9
Intermitt. access escalation Index0.40.61.10.4-0.6-0.5-0.80.2-0.8-0.5-0.80.8-0.6-0.90.6-1.0-0.9-0.90.9-0.9-1.11.1-0.9-0.8-0.8-0.9-0.90.7-0.6
Intermittent access day 1 total infusions0.20.41.70.40.1-0.20.30.30.40.30.3-0.31.20.5-1.20.50.50.5-0.50.20.4-0.40.60.60.70.60.0-1.3-0.8
Intermittent access day 15 total infusions0.10.20.80.80.80.90.70.70.30.40.30.20.1-0.0-0.10.0-0.1-0.10.1-0.10.1-0.1-0.00.00.3-0.3-0.20.0-0.7
Intermittent access terminal intake (last 3 days)0.70.92.11.21.41.31.41.21.11.11.1-0.60.70.9-0.71.00.80.8-0.80.81.0-1.00.90.91.20.50.7-0.8-0.2
Intermittent access total infusions0.40.52.21.51.21.21.11.50.70.90.70.00.40.3-0.40.40.10.3-0.10.10.3-0.30.30.40.6-0.20.1-0.3-0.6
Intermittent access day 1 locomotion0.30.41.1-0.2-0.8-0.7-0.70.2-0.7-0.4-0.70.70.1-0.7-0.1-0.6-0.6-0.60.6-0.7-0.70.7-0.5-0.5-0.5-0.5-0.8-0.2-1.0
Intermittent access day 15 total locomotion0.50.91.50.71.10.91.20.51.10.91.2-0.90.51.1-0.51.10.91.0-0.91.01.2-1.21.11.11.10.90.9-0.90.1
Intermittent access total locomotion0.10.10.30.40.10.20.40.60.20.40.3-0.10.00.2-0.00.30.20.2-0.20.30.2-0.20.30.30.20.10.2-0.4-0.3
Intermittent access standard deviation0.91.83.1-0.20.60.30.9-0.21.30.71.3-1.51.11.7-1.11.61.61.6-1.61.41.6-1.61.71.61.61.81.6-1.60.5
Left kidney weight0.10.31.7-0.8-1.3-1.2-0.9-0.8-0.4-0.4-0.4-0.1-0.50.20.50.10.20.2-0.20.40.0-0.00.20.1-0.10.50.1-0.6-0.3
Right kidney weight0.42.06.0-2.0-2.5-2.2-2.1-1.9-1.7-1.7-1.61.0-1.5-1.11.5-1.1-0.9-1.10.9-0.9-1.21.2-0.9-1.0-1.3-0.5-1.00.4-1.1
Cocaine induced anxiety1.11.54.2-1.4-2.1-2.0-1.9-1.5-1.6-1.6-1.60.9-0.6-1.10.6-1.1-0.9-1.00.9-1.0-1.21.2-1.0-1.1-1.2-0.7-0.90.4-0.5
Post-drug Anxiety4.54.86.6-1.5-2.3-1.6-2.4-1.5-2.6-2.1-2.52.3-1.7-2.31.7-2.4-2.4-2.32.4-2.1-2.52.5-2.4-2.5-2.4-2.3-2.12.0-1.4
Baseline Anxiety0.40.51.00.30.30.90.10.3-0.4-0.1-0.31.0-0.5-0.70.5-0.7-0.9-0.80.9-0.7-0.70.7-0.8-0.8-0.6-1.0-0.81.0-0.9
Tail length0.31.32.6-0.9-1.1-0.7-1.2-0.8-1.3-1.1-1.21.2-1.2-1.11.2-1.2-1.2-1.11.2-1.0-1.21.2-1.1-1.1-1.4-1.0-1.30.7-1.6
Length with tail0.62.85.4-2.3-2.2-2.0-2.3-2.2-2.0-2.2-1.91.4-1.5-1.51.4-1.6-1.4-1.61.3-1.6-1.71.7-1.4-1.5-1.7-0.8-1.40.8-1.1
Length without tail0.41.36.9-2.5-2.0-2.6-1.8-2.4-0.9-1.6-1.0-0.30.0-0.1-0.1-0.10.3-0.2-0.3-0.3-0.20.20.1-0.1-0.20.9-0.2-0.90.2
Times rat made contact with spout0.10.10.30.50.40.60.50.50.40.40.4-0.2-0.00.40.00.30.20.3-0.20.20.4-0.40.30.30.30.30.2-0.3-0.5
Lifetime Intake0.40.51.91.31.00.91.01.40.70.80.7-0.20.70.4-0.70.50.30.4-0.30.20.4-0.40.50.50.80.10.2-0.6-0.5
Liver weight, left0.61.05.6-2.1-1.9-2.4-1.5-1.9-0.6-1.1-0.6-0.6-0.20.20.20.20.50.1-0.50.10.1-0.10.30.20.01.20.2-0.90.6
Liver weight, right1.52.74.40.30.6-0.11.00.11.61.11.5-2.01.82.0-1.81.92.01.9-2.01.81.9-1.91.91.91.52.11.5-2.10.8
Locomotor activity2.64.114.0-3.7-3.4-3.7-3.1-3.6-2.4-3.2-2.40.9-0.8-1.30.8-1.3-0.9-1.50.9-1.6-1.51.5-1.1-1.3-1.5-0.0-1.00.0-0.6
Locomotor testing distance6.211.217.2-3.8-3.9-3.3-4.1-3.6-3.9-4.2-3.93.1-2.4-3.52.3-3.4-3.1-3.53.1-3.6-3.63.6-3.3-3.4-3.5-2.4-3.02.1-2.0
Locomotor testing rearing7.615.323.2-4.1-4.6-3.9-4.8-4.1-4.6-4.8-4.63.6-2.9-4.12.8-4.0-3.6-4.23.6-4.3-4.24.2-3.9-4.0-4.1-2.7-3.72.4-2.4
Locomotion in novel chamber0.10.11.30.1-0.00.30.00.3-0.10.1-0.10.40.7-0.1-0.7-0.2-0.30.00.30.1-0.10.1-0.2-0.1-0.3-0.4-0.5-0.2-1.1
Locomotion in novel chamber post-restriction0.50.74.0-0.10.3-0.20.3-0.30.50.30.4-0.62.00.8-2.00.71.00.9-1.00.90.8-0.80.80.71.00.70.5-1.30.1
Fecal boli incidents, locomotor time 11.01.54.2-0.6-0.2-0.50.5-0.90.90.30.9-1.51.31.3-1.31.61.41.4-1.41.51.3-1.31.41.60.61.81.1-2.1-0.2
Change in fecal boli incidents, locomotor task0.40.41.70.90.60.70.40.90.20.30.3-0.0-1.2-0.01.2-0.3-0.2-0.10.2-0.40.0-0.0-0.2-0.4-0.0-0.70.11.31.0
Time >=10cm from walls, locomotor time 11.21.23.5-0.8-1.0-0.5-1.0-0.2-1.1-0.6-1.01.1-1.9-0.91.9-1.2-1.2-0.91.2-0.8-1.11.1-1.1-1.2-1.4-1.3-1.01.4-0.6
Bouts of movement, locomotor time 10.80.94.10.40.60.20.70.40.90.80.8-1.11.00.7-1.00.91.11.0-1.11.10.8-0.81.00.90.80.91.3-0.62.0
Total resting periods, locomotor time 11.71.84.51.01.30.81.31.01.41.41.4-1.51.51.2-1.51.31.51.5-1.51.41.2-1.21.41.31.41.11.7-0.82.1
Rest time, locomotor task time 11.51.83.31.31.61.21.51.11.51.51.5-1.21.81.2-1.81.21.41.3-1.31.31.2-1.21.31.21.50.81.2-0.81.3
Distance moved, locomotor task time 10.91.32.7-0.5-0.9-0.5-1.0-0.3-1.2-0.8-1.11.3-1.7-1.11.6-1.2-1.4-1.21.4-1.1-1.11.1-1.3-1.3-1.3-1.2-1.31.1-1.1
Vertical activity count, locomotor time 10.81.85.2-2.1-2.2-2.3-2.0-1.9-1.7-1.9-1.70.8-0.7-1.00.7-1.1-0.9-1.10.9-1.1-0.90.9-1.0-1.0-1.1-0.4-1.20.1-0.9
Time >=10cm from walls, locomotor time 20.10.10.3-0.3-0.2-0.4-0.0-0.10.2-0.00.2-0.5-0.40.50.40.20.30.3-0.30.10.3-0.30.30.40.10.30.3-0.00.4
Bouts of movement, locomotor time 21.21.94.60.41.30.71.30.21.50.91.5-1.81.21.5-1.21.51.61.4-1.61.21.3-1.31.51.61.71.61.9-0.82.2
Total resting periods, locomotor time 22.13.66.20.81.81.01.80.62.11.52.1-2.41.62.1-1.52.12.22.0-2.21.81.8-1.82.12.22.22.12.4-1.22.5
Rest time, locomotor task time 27.29.212.61.62.51.82.91.43.22.83.2-3.23.53.4-3.53.43.33.5-3.33.53.3-3.33.33.33.13.02.9-3.01.7
Distance moved, locomotor task time 23.74.45.7-1.4-2.0-1.4-2.1-1.2-2.3-2.0-2.32.4-2.0-2.12.0-2.3-2.3-2.32.3-2.2-2.22.2-2.3-2.2-2.1-2.0-2.41.5-2.0
Vertical activity count, locomotor time 22.33.26.4-2.1-2.5-2.4-2.5-2.1-2.2-2.4-2.21.5-0.6-1.60.5-1.7-1.4-1.81.4-1.9-1.81.8-1.6-1.5-1.6-0.8-1.80.2-1.8
Light reinforcement 10.20.42.10.30.30.90.20.3-0.2-0.0-0.20.8-0.8-0.50.8-0.5-0.8-0.60.8-0.7-0.50.5-0.6-0.5-0.5-0.6-0.70.7-1.4
Light reinforcement 21.42.15.02.12.12.22.21.91.91.91.9-1.10.41.3-0.31.41.01.2-1.01.11.3-1.31.21.51.20.91.3-0.30.5
Bone: marrow area0.30.71.1-0.9-1.0-0.8-1.1-0.9-1.0-0.9-1.00.9-0.8-0.90.8-0.8-0.8-0.90.8-0.7-0.90.9-0.9-0.9-0.9-0.7-0.90.6-0.6
Bone: maximum diameter0.10.20.6-0.6-0.4-0.7-0.3-0.50.1-0.20.0-0.50.70.4-0.70.40.50.3-0.50.30.4-0.40.50.40.50.80.3-0.80.0
Bone: maximum force0.30.52.6-1.6-1.4-1.6-1.1-1.6-0.7-0.9-0.7-0.00.1-0.2-0.2-0.1-0.0-0.1-0.00.1-0.20.2-0.1-0.2-0.50.4-0.2-0.50.1
Bone: maximum moment0.61.14.4-2.1-2.0-2.0-1.6-2.0-1.1-1.4-1.10.3-0.2-0.50.2-0.4-0.3-0.50.3-0.2-0.50.5-0.4-0.5-0.90.2-0.5-0.3-0.2
Mean time between licks in bursts1.43.46.30.1-0.40.4-1.00.3-1.6-0.9-1.52.4-2.5-2.22.5-2.1-2.3-2.02.3-1.9-2.02.0-2.2-2.1-1.6-2.3-1.82.4-1.1
Mean num. licks in bursts0.00.10.4-0.5-0.5-0.5-0.4-0.6-0.2-0.4-0.2-0.1-0.10.10.1-0.00.0-0.1-0.0-0.10.0-0.00.1-0.0-0.00.3-0.1-0.3-0.5
Cd content in liver0.50.63.1-1.6-1.3-1.8-1.1-1.7-0.5-1.1-0.6-0.40.10.1-0.10.10.30.0-0.40.1-0.20.20.20.20.00.70.2-0.60.4
Co content in liver2.32.74.20.41.00.11.20.11.61.01.6-2.11.61.9-1.51.92.01.8-2.01.71.8-1.81.91.91.92.01.8-1.71.7
Cu content in liver0.80.91.70.30.70.20.70.41.00.91.0-1.10.81.1-0.81.11.21.1-1.21.21.0-1.01.11.21.31.11.0-1.00.7
Fe content in liver1.41.74.10.2-0.20.3-0.60.1-1.0-0.7-0.91.5-2.0-1.42.0-1.4-1.5-1.51.6-1.4-1.31.3-1.5-1.3-1.1-1.7-1.11.9-0.7
K content in liver0.50.52.01.21.11.40.71.40.20.70.30.5-0.9-0.30.9-0.4-0.5-0.30.5-0.4-0.30.3-0.4-0.30.1-0.7-0.11.10.0
Mg content in liver0.50.51.20.60.40.80.00.7-0.4-0.0-0.41.0-0.6-0.80.6-0.9-0.9-0.80.9-0.9-0.80.8-0.8-0.8-0.4-1.1-0.81.0-0.9
Mn content in liver1.31.53.50.0-0.40.2-0.7-0.2-1.1-0.9-1.11.6-0.6-1.40.6-1.4-1.5-1.41.5-1.5-1.31.3-1.4-1.4-1.1-1.5-1.61.1-1.9
Na content in liver1.11.15.9-2.4-1.9-2.4-1.5-2.4-0.9-1.6-0.9-0.40.00.1-0.0-0.00.4-0.1-0.4-0.1-0.00.00.2-0.1-0.11.10.2-0.70.4
Rb content in liver0.10.20.70.60.60.60.40.60.30.40.4-0.1-0.80.10.80.1-0.00.10.00.10.0-0.00.00.10.4-0.20.20.60.2
Se content in liver4.95.87.9-2.0-2.4-1.9-2.7-2.0-2.8-2.7-2.72.5-2.0-2.72.0-2.6-2.4-2.72.4-2.8-2.72.7-2.5-2.5-2.4-2.0-2.12.1-1.2
Sr content in liver0.80.71.7-0.3-0.5-0.3-0.7-0.6-0.8-0.8-0.80.7-1.1-0.91.1-0.9-0.8-1.00.8-1.0-0.90.9-0.9-0.9-0.7-0.8-0.51.30.4
Zn content in liver0.80.91.5-0.6-0.8-0.5-1.0-0.6-1.1-1.0-1.11.1-0.8-1.10.8-1.1-1.0-1.11.0-1.2-1.21.2-1.0-1.1-0.9-0.9-1.00.8-0.7
Bone: minimum diameter0.50.83.3-1.8-1.7-1.8-1.5-1.6-1.1-1.3-1.10.3-0.1-0.50.1-0.4-0.3-0.60.3-0.4-0.50.5-0.4-0.5-0.70.1-0.6-0.4-0.7
Time in familiar zone, hab. session 10.10.10.20.40.20.50.10.20.0-0.0-0.00.3-0.4-0.30.4-0.2-0.3-0.30.3-0.4-0.30.3-0.3-0.2-0.5-0.3-0.10.5-0.1
Time in novel zone, hab. session 12.12.13.00.30.80.11.10.41.41.11.4-1.71.71.7-1.71.61.71.6-1.71.61.7-1.71.61.61.71.61.5-1.61.1
Total zone transitions, hab. session 10.40.51.7-1.3-1.2-1.3-1.1-1.2-0.9-1.1-0.90.3-0.3-0.50.3-0.5-0.3-0.60.3-0.7-0.60.6-0.4-0.5-0.4-0.0-0.40.1-0.2
Total locomotion distance, hab. session 11.21.72.7-1.5-1.6-1.4-1.6-1.2-1.6-1.6-1.61.2-1.2-1.41.2-1.4-1.2-1.41.2-1.5-1.41.4-1.3-1.3-1.2-0.8-1.10.8-0.6
Locomotion velocity, hab. session 13.04.26.1-2.2-2.3-2.0-2.5-1.8-2.4-2.4-2.41.9-1.9-2.21.9-2.1-1.9-2.21.9-2.4-2.22.2-2.0-2.1-1.9-1.4-1.81.4-1.0
Time in familiar zone, hab. session 20.80.92.11.31.41.41.40.91.11.21.1-0.60.60.7-0.60.80.60.8-0.61.00.9-0.90.70.80.70.20.9-0.01.3
Time in novel zone, hab. session 20.50.51.3-1.1-1.1-1.1-1.1-0.7-0.9-1.0-0.90.4-0.6-0.50.5-0.6-0.5-0.70.5-0.9-0.70.7-0.5-0.6-0.5-0.1-0.60.1-0.7
Total zone transitions, hab. session 20.70.93.8-1.9-1.5-1.9-1.5-1.8-1.0-1.5-1.00.00.1-0.4-0.1-0.5-0.1-0.50.1-0.6-0.60.6-0.3-0.5-0.10.3-0.2-0.10.6
Total locomotion distance, hab. session 20.50.71.7-1.3-1.1-1.3-1.2-1.0-1.0-1.2-1.00.4-0.5-0.80.5-0.8-0.5-0.80.5-1.0-0.90.9-0.6-0.7-0.4-0.1-0.40.40.4
Locomotion velocity, hab. session 20.60.82.7-1.6-1.3-1.6-1.4-1.4-1.1-1.4-1.10.3-0.4-0.70.3-0.7-0.4-0.70.4-0.9-0.90.9-0.6-0.7-0.40.0-0.30.20.5
Novel to familiar place preference ratio0.60.71.3-0.9-1.0-0.8-0.9-0.8-0.9-0.9-0.90.7-1.2-0.81.2-0.7-0.8-0.80.8-0.8-0.80.8-0.8-0.7-1.0-0.5-0.80.5-0.6
Novelty place preference0.90.91.7-0.9-1.1-0.8-1.1-0.9-1.0-1.1-1.00.8-1.3-0.91.3-0.9-0.9-0.90.9-1.0-0.90.9-0.9-0.9-1.2-0.7-0.90.7-0.5
Time in novel zone, NPP test0.90.91.4-1.0-1.2-1.0-1.1-1.0-1.1-1.1-1.10.8-1.2-0.91.2-0.9-0.9-0.90.9-1.0-0.90.9-0.9-0.9-1.1-0.6-0.80.7-0.3
Total zone transitions, NPP test1.82.63.5-1.5-1.5-1.3-1.8-1.5-1.8-1.9-1.81.5-1.4-1.71.4-1.8-1.5-1.81.5-1.9-1.81.8-1.7-1.8-1.3-1.3-1.51.4-0.9
Total locomotion distance, NPP test5.37.210.3-1.3-1.8-0.9-2.3-1.1-2.8-2.4-2.73.0-3.0-3.13.0-3.1-2.9-3.03.0-3.2-3.13.1-3.0-3.0-2.7-2.8-2.72.6-2.1
Locomotion velocity, NPP test4.15.78.1-1.2-1.6-0.8-2.0-0.9-2.4-2.1-2.42.7-2.8-2.72.7-2.7-2.7-2.72.7-2.8-2.82.8-2.7-2.7-2.3-2.6-2.52.3-2.0
Intraocular pressure1.31.92.9-0.5-0.6-0.2-1.0-0.5-1.4-1.1-1.31.7-1.5-1.51.5-1.6-1.6-1.71.6-1.6-1.61.6-1.6-1.6-1.0-1.6-1.31.7-0.6
Delta distance traveled before/after self-admin0.50.51.0-0.30.60.20.7-0.40.80.20.7-1.00.70.8-0.70.80.90.6-0.90.30.7-0.70.80.80.80.80.8-0.50.9
Delta ambulatory time before/after self-admin0.40.51.1-0.70.4-0.10.5-0.90.6-0.20.6-1.01.00.8-1.00.80.90.5-0.90.10.7-0.70.70.80.70.90.7-0.70.6
Parametrial fat weight1.53.56.7-0.0-0.60.5-0.90.1-1.6-0.8-1.52.5-1.3-2.21.3-2.1-2.4-2.12.4-2.0-2.12.1-2.3-2.1-2.2-2.6-2.42.0-2.5
Pavlov. Cond. lever latency0.30.41.51.11.21.20.91.00.60.90.6-0.00.40.2-0.40.20.10.3-0.10.50.3-0.30.10.20.5-0.30.30.40.5
Pavlov. Cond. magazine entry latency0.00.00.3-0.3-0.3-0.2-0.2-0.2-0.1-0.2-0.10.0-0.20.10.2-0.0-0.0-0.00.0-0.2-0.10.1-0.0-0.0-0.20.2-0.2-0.2-0.6
Pavlov. Cond. change in total contacts0.80.94.6-1.9-1.7-2.1-1.2-1.9-0.5-1.2-0.6-0.60.40.3-0.40.30.50.2-0.5-0.00.1-0.10.40.2-0.11.20.3-1.00.3
Pavlov. Cond. index score0.20.31.2-1.1-1.0-1.1-0.7-1.0-0.3-0.7-0.3-0.30.00.2-0.00.10.20.1-0.3-0.10.0-0.00.20.1-0.10.70.1-0.7-0.3
Pavlov. Cond. latency score0.20.31.3-1.1-1.1-1.1-0.8-1.0-0.4-0.8-0.4-0.1-0.20.00.2-0.00.0-0.1-0.1-0.3-0.20.20.0-0.0-0.30.5-0.1-0.5-0.4
Pavlov. Cond. lever contacts0.20.31.1-1.0-1.0-1.0-0.8-0.9-0.5-0.8-0.50.0-0.4-0.10.4-0.2-0.1-0.20.1-0.5-0.20.2-0.1-0.2-0.40.4-0.3-0.4-0.6
Pavlov. Cond. magazine entry number0.30.41.10.70.50.70.20.6-0.20.1-0.20.7-0.6-0.70.6-0.6-0.7-0.60.7-0.5-0.50.5-0.7-0.6-0.4-1.1-0.51.0-0.0
Pavlov. Cond. intertrial magazine entries1.51.82.9-1.5-1.5-1.3-1.5-1.6-1.6-1.7-1.51.2-1.3-1.41.3-1.3-1.3-1.41.3-1.4-1.31.3-1.3-1.4-1.3-1.0-1.21.0-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.31.3-1.1-1.0-1.1-0.6-1.0-0.2-0.6-0.2-0.50.20.4-0.20.30.40.3-0.40.00.2-0.20.40.3-0.00.90.2-0.8-0.1
Pavlov. Cond. response bias0.30.31.1-0.6-0.4-0.6-0.1-0.50.3-0.10.2-0.70.50.7-0.50.60.70.6-0.70.40.6-0.60.70.60.41.00.4-1.0-0.1
Pavlov. Cond. lever latency0.50.73.31.81.41.81.11.80.61.10.60.4-0.5-0.20.5-0.1-0.4-0.00.4-0.1-0.10.1-0.3-0.1-0.1-0.8-0.00.8-0.1
Pavlov. Cond. magazine entry latency0.20.31.4-1.0-0.9-1.0-0.8-1.2-0.6-0.9-0.50.1-0.3-0.10.3-0.2-0.1-0.30.1-0.3-0.10.1-0.1-0.2-0.10.3-0.3-0.2-0.5
Pavlov. Cond. change in total contacts0.71.23.4-1.7-1.0-1.7-0.6-1.80.1-0.70.1-1.21.21.0-1.20.91.10.8-1.20.90.8-0.81.00.80.91.60.8-1.40.8
Pavlov. Cond. index score0.40.63.1-1.7-1.3-1.7-1.0-1.8-0.5-1.1-0.5-0.40.40.2-0.40.20.40.0-0.40.10.1-0.10.30.10.20.90.1-0.80.1
Pavlov. Cond. latency score0.50.63.2-1.7-1.4-1.7-1.2-1.8-0.8-1.2-0.7-0.10.2-0.1-0.2-0.10.1-0.2-0.2-0.1-0.10.10.0-0.1-0.00.6-0.1-0.5-0.1
Pavlov. Cond. lever contacts0.50.73.4-1.8-1.5-1.8-1.1-1.8-0.6-1.1-0.6-0.40.40.2-0.40.10.40.0-0.40.10.0-0.00.30.10.10.80.0-0.8-0.0
Pavlov. Cond. magazine entry number0.40.41.51.01.01.00.91.20.81.00.8-0.40.50.4-0.50.50.40.6-0.40.60.5-0.50.40.50.40.10.5-0.10.6
Pavlov. Cond. intertrial magazine entries4.26.411.20.5-0.70.6-1.20.6-2.0-1.1-2.03.2-3.1-3.03.1-2.8-3.1-2.83.1-2.8-2.82.8-2.9-2.8-3.0-3.3-2.72.9-2.4
Pavlov. Cond. lever-magazine prob. diff.0.40.62.8-1.6-1.2-1.6-0.9-1.7-0.4-0.9-0.4-0.50.50.3-0.50.30.50.1-0.50.20.3-0.30.40.20.31.00.2-0.80.2
Pavlov. Cond. response bias0.50.74.0-1.9-1.5-1.9-1.2-2.0-0.7-1.3-0.7-0.30.40.1-0.40.00.3-0.0-0.30.0-0.00.00.2-0.00.00.8-0.0-0.7-0.1
Time in closed arm before self-admin0.20.31.5-0.00.30.00.40.20.50.40.5-0.8-0.10.50.10.50.60.4-0.60.40.5-0.50.50.40.50.70.8-0.21.2
Time in closed arm after self-admin0.40.41.1-0.3-0.2-0.1-0.3-0.3-0.6-0.7-0.50.6-0.9-0.80.9-0.7-0.7-0.80.7-1.0-0.70.7-0.8-0.6-0.6-0.7-0.41.00.2
Time in open arm before self-admin0.80.91.6-1.3-1.0-0.6-0.9-1.1-1.1-1.1-1.11.0-0.0-1.1-0.0-1.1-1.0-1.01.0-1.0-1.11.1-1.1-0.9-1.0-0.9-1.00.7-0.5
Time in open arm after self-admin0.00.00.10.2-0.00.0-0.00.1-0.00.1-0.00.1-0.1-0.10.1-0.1-0.1-0.10.10.2-0.20.2-0.1-0.2-0.1-0.20.00.30.2
Bone: periosteal estimation0.30.61.4-1.2-1.2-1.1-1.1-1.0-0.9-0.9-0.90.6-0.5-0.60.4-0.6-0.6-0.60.6-0.4-0.60.6-0.6-0.6-0.7-0.3-0.70.1-0.6
Bone: periosteal perimeter0.81.42.3-1.4-1.5-1.3-1.5-1.3-1.4-1.5-1.41.0-1.0-1.21.0-1.2-1.0-1.31.0-1.2-1.21.2-1.1-1.2-1.0-0.7-1.10.7-0.6
Bone: post-yield work1.62.33.51.51.71.51.91.51.81.91.8-1.41.21.6-1.11.71.31.7-1.31.71.7-1.71.51.71.41.11.3-1.20.4
Progressive ratio test 1 active lever presses1.31.72.41.51.41.01.51.41.51.31.4-1.11.51.3-1.51.31.21.3-1.21.01.3-1.31.31.41.31.11.0-1.5-0.0
Progressive ratio test 1 breakpoint1.41.72.41.41.30.91.41.31.51.31.4-1.21.51.4-1.51.41.31.3-1.31.01.3-1.31.41.41.41.21.0-1.50.0
Progressive ratio test 1 inactive lever presses0.30.51.40.80.61.00.30.7-0.0-0.1-0.00.6-1.0-0.51.0-0.6-0.7-0.70.7-1.2-0.70.7-0.7-0.5-0.4-0.8-0.71.0-0.7
Progressive ratio test 2 active lever presses0.91.01.70.61.00.41.00.41.10.81.1-1.10.71.2-0.61.21.11.1-1.10.91.2-1.21.21.31.31.30.9-1.3-0.2
Progressive ratio test 2 breakpoint0.80.91.70.40.80.30.80.31.00.61.0-1.00.61.2-0.61.11.11.1-1.10.91.1-1.11.21.21.21.30.9-1.3-0.2
Progressive ratio test 2 inactive lever presses0.30.51.81.31.41.11.11.10.80.80.9-0.5-0.30.70.30.60.40.6-0.40.40.6-0.60.60.70.80.30.4-0.3-0.5
Incentive Sensitization - Responses0.20.42.0-1.4-0.6-1.0-0.5-1.4-0.2-0.7-0.2-0.4-0.20.40.20.30.40.3-0.40.20.3-0.30.40.40.30.90.2-0.8-0.5
Incentive Sensitization - Breakpoint0.30.31.9-1.4-0.6-0.9-0.6-1.4-0.3-0.7-0.2-0.3-0.20.30.20.20.30.3-0.30.20.2-0.20.30.30.30.80.1-0.7-0.7
Sum of active levers in priming session hrs 5-60.40.32.31.01.21.51.01.00.70.70.7-0.0-0.30.20.30.2-0.10.00.10.00.2-0.20.10.30.1-0.30.10.50.1
Progressive ratio0.40.61.9-0.7-0.3-0.8-0.1-0.70.3-0.20.3-1.10.60.7-0.60.70.90.7-0.90.50.9-0.90.80.70.91.40.9-0.81.3
Food seeking constrained by brief footshock3.13.87.62.12.82.22.42.42.32.32.4-2.00.91.8-0.91.71.81.7-1.81.61.7-1.71.81.82.51.22.2-0.32.5
Seeking ratio, punishment vs. effort0.60.93.01.41.71.61.51.51.21.41.2-0.60.40.7-0.40.70.60.8-0.60.90.5-0.50.60.71.0-0.00.80.20.6
Retroperitoneal fat weight0.31.22.20.1-0.10.6-0.30.2-0.8-0.5-0.81.5-0.8-1.30.8-1.2-1.4-1.21.4-1.3-1.31.3-1.3-1.1-1.4-1.5-1.21.2-1.3
Reaction time number correct0.10.10.80.40.80.50.50.40.50.40.5-0.3-0.20.30.20.20.30.2-0.30.10.1-0.10.20.20.40.00.30.30.9
Reaction time mean minus median0.20.41.3-1.0-0.9-0.8-0.8-1.1-0.7-0.9-0.60.2-0.8-0.40.8-0.5-0.4-0.50.4-0.3-0.50.5-0.5-0.5-0.4-0.3-0.20.60.4
Reaction time mean minus median AUC0.10.20.9-0.5-0.5-0.4-0.5-0.6-0.4-0.7-0.30.1-0.9-0.21.0-0.3-0.2-0.40.2-0.5-0.40.4-0.3-0.3-0.1-0.1-0.00.60.3
Reaction time num false alarms0.60.82.0-1.4-1.1-1.0-1.1-1.2-1.0-1.2-1.00.8-0.5-0.80.5-0.9-0.7-0.80.7-1.0-0.90.9-0.8-0.9-0.8-0.7-0.80.5-0.6
Reaction time num false alarms AUC0.30.42.1-1.4-1.0-0.9-0.8-1.3-0.7-1.0-0.70.3-0.2-0.30.2-0.4-0.3-0.40.3-0.6-0.40.4-0.4-0.4-0.5-0.2-0.5-0.0-0.6
Reaction time trials correct on left0.10.10.80.40.80.50.50.40.50.40.5-0.3-0.20.30.20.20.30.2-0.30.10.1-0.10.20.20.40.00.30.30.9
Reaction time trials on left0.10.10.70.40.80.60.50.50.50.40.5-0.2-0.20.20.30.20.20.1-0.20.00.1-0.10.10.20.4-0.10.30.40.8
Reaction time mean0.10.10.60.0-0.1-0.30.1-0.00.10.00.2-0.4-0.40.30.40.30.30.2-0.30.30.3-0.30.30.20.30.20.60.10.8
Reaction time mean AUC0.10.10.8-0.2-0.4-0.6-0.2-0.3-0.0-0.20.0-0.4-0.40.20.40.20.20.1-0.20.20.2-0.20.20.10.20.30.50.10.9
Median of all reaction times0.20.20.70.40.2-0.10.40.30.40.40.5-0.6-0.10.50.10.60.50.5-0.50.60.6-0.60.60.50.50.50.8-0.10.8
Reaction time omissions0.91.33.00.4-0.20.4-0.50.3-0.8-0.4-0.81.3-1.6-1.21.6-1.3-1.4-1.21.4-1.1-1.41.4-1.4-1.3-1.2-1.6-1.11.7-0.5
Reaction time false alarm rate0.20.31.2-1.1-0.9-0.7-0.7-0.9-0.6-0.7-0.60.4-0.1-0.30.1-0.4-0.3-0.30.3-0.4-0.30.3-0.3-0.4-0.5-0.2-0.5-0.1-0.9
Reaction time premature initiation rate0.40.61.3-0.20.50.00.4-0.00.70.50.7-0.90.71.0-0.70.81.01.0-1.01.00.7-0.70.90.81.10.91.0-0.61.0
Reaction time premature initiations0.50.92.00.20.90.40.80.21.00.71.0-1.10.71.1-0.71.01.21.1-1.11.00.8-0.81.01.01.30.91.2-0.51.4
Std. dev. reaction times0.00.10.3-0.1-0.1-0.1-0.0-0.2-0.0-0.10.1-0.2-0.50.10.50.10.10.1-0.10.20.0-0.00.10.00.30.00.30.30.6
Reaction time trials completed0.10.10.70.40.80.60.50.50.50.40.5-0.2-0.20.20.30.20.20.1-0.20.00.1-0.10.10.20.4-0.10.30.40.8
Reaction time trials AUC0.10.10.60.40.70.50.40.40.40.30.4-0.2-0.30.20.30.10.10.1-0.1-0.00.1-0.10.10.10.3-0.10.20.40.8
Run reversals in cocaine runway, females0.20.20.80.90.50.80.20.6-0.10.3-0.10.60.8-0.3-0.8-0.3-0.4-0.20.4-0.1-0.30.3-0.3-0.20.0-0.5-0.40.0-0.8
Run reversals in cocaine runway, males3.83.89.0-0.50.2-1.00.6-0.21.41.01.3-2.42.32.4-2.32.22.52.2-2.52.42.1-2.12.42.12.12.71.7-3.00.4
Latency to leave start box in cocaine runway0.50.61.80.40.3-0.20.30.10.70.30.6-1.10.40.9-0.30.71.10.8-1.00.40.7-0.70.90.81.31.11.0-0.71.2
Latency to leave start box in cocaine runway, F1.41.63.40.10.2-0.60.4-0.21.10.51.0-1.80.51.5-0.51.41.71.5-1.71.01.4-1.41.61.41.81.91.5-1.41.4
Latency to leave start box in cocaine runway, M0.10.10.40.20.00.0-0.30.0-0.2-0.2-0.20.3-0.2-0.30.2-0.5-0.3-0.40.3-0.5-0.60.6-0.4-0.50.0-0.3-0.10.60.4
Std. dev. time between licks in bursts6.99.312.6-1.9-2.4-1.6-2.9-1.9-3.3-2.9-3.23.4-3.6-3.53.5-3.4-3.3-3.33.3-3.2-3.43.4-3.4-3.5-3.0-3.0-2.93.2-1.2
Total sessions with >9 infusions0.10.21.00.80.40.40.51.00.50.50.4-0.20.30.2-0.30.30.30.2-0.3-0.00.3-0.30.30.30.50.10.2-0.30.0
Short access day 1 total inactive lever presses2.02.75.60.90.60.21.21.21.41.51.4-1.52.21.7-2.21.91.71.8-1.72.01.9-1.91.91.81.81.71.4-2.4-0.1
Short access day 10 total inactive lever presses0.00.00.20.1-0.10.20.00.3-0.10.1-0.10.3-0.2-0.30.2-0.2-0.2-0.20.2-0.1-0.10.1-0.2-0.2-0.4-0.4-0.30.3-0.3
Short access day 1 total infusions0.91.22.91.30.90.81.21.71.21.21.2-0.91.20.9-1.21.11.00.9-1.00.61.1-1.11.11.11.30.70.9-1.10.3
Short access day 10 total infusions0.40.52.6-0.5-0.6-1.0-0.3-0.60.1-0.40.0-0.51.40.5-1.50.50.70.5-0.70.20.4-0.40.70.50.61.00.2-1.6-0.5
Short access total infusions0.40.51.70.30.0-0.20.40.50.50.30.5-0.61.20.7-1.20.70.80.6-0.80.30.7-0.70.80.80.90.80.5-1.3-0.2
Short access day 1 locomotion0.30.31.5-0.8-0.9-1.2-0.4-0.5-0.0-0.4-0.1-0.40.60.3-0.60.40.60.2-0.60.00.3-0.30.50.40.40.90.1-1.2-0.2
Short access day 10 total locomotion0.10.10.6-0.3-0.8-0.4-0.30.0-0.4-0.3-0.30.3-0.4-0.40.4-0.2-0.3-0.30.3-0.5-0.30.3-0.2-0.2-0.5-0.2-0.10.1-0.1
Short access total locomotion0.10.11.0-0.7-1.0-1.0-0.6-0.3-0.3-0.4-0.3-0.00.2-0.1-0.20.00.1-0.1-0.1-0.1-0.10.10.10.0-0.10.3-0.0-0.6-0.2
One hour access (0.3 mA shock)0.20.22.80.30.10.10.20.40.10.20.00.30.9-0.1-0.90.1-0.0-0.00.00.10.1-0.10.10.10.30.1-0.5-0.9-1.7
Compulsive drug intake1.51.83.40.2-0.9-0.4-1.10.3-1.3-0.7-1.31.7-0.8-1.60.8-1.6-1.6-1.61.6-1.3-1.61.6-1.6-1.5-1.4-1.6-1.90.9-1.8
One hour access (shock baseline)0.30.40.90.40.80.50.80.40.70.50.7-0.50.90.6-0.90.70.70.6-0.70.50.7-0.70.70.71.00.50.6-0.8-0.0
Social response proportion0.91.13.81.61.91.91.51.91.21.51.3-0.7-0.80.60.80.50.40.6-0.40.40.4-0.40.40.70.80.10.80.80.9
Social responses2.63.38.6-0.00.31.1-0.60.2-1.2-0.8-1.12.0-2.6-1.92.6-2.1-2.2-2.12.2-2.3-2.12.1-2.1-2.0-1.6-2.3-1.62.9-1.0
Social time1.21.72.3-1.2-1.5-1.2-1.5-1.0-1.4-1.5-1.41.2-1.5-1.31.5-1.3-1.2-1.41.2-1.5-1.21.2-1.3-1.3-1.5-0.9-1.21.0-1.1
Soleus weight0.61.83.00.50.90.21.00.71.31.11.2-1.51.71.4-1.71.41.51.4-1.51.41.4-1.41.41.41.71.31.2-1.31.3
Bone: stiffness0.20.30.7-0.4-0.3-0.5-0.0-0.50.30.10.3-0.70.80.6-0.80.60.70.6-0.70.80.6-0.60.60.60.40.70.5-0.80.5
Tibialis anterior weight3.110.624.0-1.6-0.1-2.20.6-1.52.00.81.9-4.14.93.4-4.93.44.03.3-4.03.43.2-3.23.73.23.54.43.2-4.13.4
Time to tail flick, vehicle, before self-admin0.10.11.00.2-0.00.2-0.10.7-0.20.1-0.20.4-0.3-0.30.3-0.3-0.4-0.30.4-0.3-0.30.3-0.3-0.2-0.4-0.3-0.50.1-1.0
Time to tail flick, vehicle, after self-admin2.53.39.51.31.60.91.61.02.01.91.9-2.11.01.9-0.91.81.91.9-1.92.32.0-2.01.81.91.91.42.2-0.73.1
Time to tail flick, test, before self-admin1.71.84.6-0.5-0.40.4-0.7-0.2-1.2-0.7-1.21.9-0.6-1.50.6-1.5-1.7-1.51.7-1.3-1.51.5-1.6-1.7-1.5-1.7-1.61.2-2.1
Time to tail flick, test, after self-admin1.51.57.01.71.72.61.31.90.20.90.41.1-1.3-0.71.3-0.9-1.2-0.81.2-0.7-0.80.8-1.0-0.7-0.7-1.7-0.62.1-0.1
Delta time to tail flick, vehicle, before/after SA2.42.35.11.51.81.51.81.01.81.81.9-1.60.51.6-0.41.51.41.6-1.41.91.6-1.61.41.61.40.81.8-0.22.3
Delta time to tail flick, test, before/after SA1.61.75.42.32.22.32.02.31.51.81.6-0.7-0.60.80.70.60.50.7-0.50.70.8-0.80.60.90.8-0.20.90.81.6
Tibia length2.87.812.7-3.0-3.6-2.8-3.4-3.0-3.3-3.3-3.32.7-2.4-2.82.3-2.7-2.6-2.82.6-2.6-2.82.8-2.6-2.8-3.1-1.9-2.71.4-2.5
Ambulatory time before self-admin0.20.41.5-0.8-0.9-1.2-0.6-0.9-0.2-0.4-0.2-0.40.80.3-0.80.40.50.3-0.50.50.3-0.30.40.40.10.80.3-1.10.1
Ambulatory time after self-admin1.51.84.7-1.8-0.7-1.5-0.1-2.20.4-0.70.4-1.51.91.2-1.91.21.61.0-1.60.91.1-1.11.31.31.01.91.3-1.81.0
Bone: tissue strength0.40.40.7-0.8-0.9-0.7-0.7-0.7-0.7-0.6-0.70.5-0.6-0.50.6-0.5-0.6-0.50.6-0.4-0.50.5-0.6-0.5-0.7-0.5-0.60.3-0.6
Total heroin consumption1.51.74.5-0.4-0.4-1.10.1-0.20.90.60.8-1.61.31.4-1.31.51.61.5-1.61.61.5-1.51.61.51.02.01.3-2.11.0
Bone: trabecular number1.42.44.30.0-0.50.3-0.80.0-1.3-0.8-1.31.9-2.1-1.72.1-1.7-1.9-1.71.9-1.7-1.71.7-1.8-1.7-1.6-1.9-1.61.9-1.4
Bone: trabecular spacing1.31.73.3-0.10.3-0.40.6-0.21.00.51.0-1.61.81.5-1.81.41.61.4-1.61.31.4-1.41.51.31.61.61.4-1.51.3
Bone: trabecular thickness0.60.71.4-0.8-0.9-0.5-0.9-0.8-0.9-0.9-0.90.8-1.1-0.91.1-0.8-0.9-0.90.9-0.8-0.80.8-0.9-0.8-1.2-0.6-0.80.6-0.8
Bone: trabecular tissue density0.60.81.5-0.4-0.3-0.80.1-0.50.50.20.5-1.11.10.9-1.11.01.01.0-1.11.11.0-1.01.01.00.71.21.0-1.21.0
Water consumed over 24 hours0.40.61.5-0.7-0.4-0.8-0.2-0.70.3-0.10.2-0.81.00.7-1.00.70.90.6-0.90.60.6-0.60.80.60.71.20.8-1.00.9
Number of responses in last shaping day0.70.81.9-0.6-0.1-0.90.0-0.70.5-0.20.5-1.11.11.0-1.11.01.00.7-1.10.60.9-0.91.00.91.11.40.8-1.30.5