Hub : Genes

Clu

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Clu 0.14 0.07 1.6e-15 0.07 0.07 0.14 0.14 3.8e-08 6.3e-09 8.7e-16 2.2e-15
2 Adipose mRNA stability Clu 0.05 0.04 2.4e-04 0.03 0.02 0.02 0.02 3.9e-04 1.7e-03 9.6e-04 9.2e-04
3 IL gene expression Clu 0.29 0.16 1.3e-03 0.06 0.05 0.1 0.08 1.8e-02 2.1e-02 2.2e-03 4.9e-03
4 BLA gene expression Clu 0.28 0.13 1.6e-10 0.15 0.14 0.15 0.16 2.2e-08 9.9e-08 1.4e-08 6.8e-09
5 OFC gene expression Clu 0.3 0.17 1.2e-03 0.04 0.07 0.07 0.06 3.3e-02 7.8e-03 1.1e-02 1.3e-02
6 Brain gene expression Clu 0.29 0.11 0.0e+00 0.25 0.32 0.32 0.32 2.3e-23 3.6e-30 3.8e-30 2.1e-30
7 PL gene expression Clu 0.24 0.12 0.0e+00 0.17 0.19 0.2 0.09 5.7e-18 7.0e-21 3.6e-21 9.8e-10
8 LHb mRNA stability Clu 0.6 0.14 1.1e-11 0.26 0.32 0.31 0.3 8.0e-07 2.0e-08 4.6e-08 7.8e-08
9 Liver gene expression Clu 0.26 0.13 0.0e+00 0.22 0.23 0.22 0.22 1.6e-24 2.9e-25 2.5e-24 1.3e-24
10 IL mRNA stability Clu 0.89 0.07 0.0e+00 0.41 0.25 0.42 0.11 6.5e-11 1.1e-06 3.7e-11 1.4e-03
11 Brain mRNA stability Clu 0.53 0.11 0.0e+00 0.62 0.64 0.64 0.65 4.9e-74 4.6e-78 5.3e-78 1.3e-79
12 NAcc mRNA stability Clu 0.35 0.1 0.0e+00 0.39 0.1 0.38 0.39 1.2e-47 4.5e-12 5.6e-47 5.9e-48
13 BLA mRNA stability Clu 0.48 0.12 0.0e+00 0.31 0.29 0.31 0.05 5.6e-17 5.8e-16 5.9e-17 1.4e-03
14 NAcc intron excision ratio chr15_40190726_40192310 0.04 0.02 1.2e-04 0.02 0 0 0 5.5e-03 1.2e-01 1.3e-01 2.5e-01
15 OFC mRNA stability Clu 0.62 0.14 6.0e-12 0.25 0.24 0.22 0.24 1.1e-06 2.2e-06 4.6e-06 2.1e-06
16 PL mRNA stability Clu 0.5 0.1 0.0e+00 0.61 0.62 0.62 0.59 7.5e-85 3.8e-86 1.5e-87 2.2e-80
17 pVTA mRNA stability Clu 0.6 0.13 1.7e-16 0.3 0.34 0.36 0.35 1.5e-13 2.8e-15 2.4e-16 8.6e-16
18 pVTA gene expression Clu 0.13 0.08 3.2e-04 0.06 0.08 0.07 0.05 9.0e-04 3.5e-04 8.3e-04 2.3e-03
19 Adipose gene expression Clu 0.73 0.11 0.0e+00 0.16 0.24 0.24 0.24 3.2e-17 2.0e-26 4.4e-26 5.9e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.01.62.80.81.41.0-0.4-0.8-0.61.3-1.21.71.5-1.5-1.51.21.61.61.51.31.31.0
Area under the delay curve0.20.21.60.20.40.4-0.9-0.3-0.40.2-0.1-0.1-0.20.30.2-0.30.1-0.3-0.2-0.5-0.7-1.3
BMI with tail0.61.92.5-1.3-1.5-1.31.31.21.2-1.51.4-1.5-1.61.51.4-1.5-1.5-1.6-1.5-1.5-0.5-1.2
BMI without tail0.20.52.4-1.10.1-0.81.61.11.1-0.60.60.1-0.10.10.2-0.2-0.4-0.2-0.3-0.31.3-0.2
Body weight0.10.21.40.40.10.1-0.6-0.5-0.6-0.1-0.1-0.5-0.40.50.3-0.3-0.4-0.5-0.4-0.5-1.2-0.1
Weight adjusted by age0.60.73.51.50.01.1-1.9-1.3-1.10.3-0.7-0.20.10.1-0.1-0.20.10.10.10.1-1.60.3
Bone surface1.11.92.61.31.51.5-1.0-1.3-1.21.5-1.51.61.6-1.5-1.51.31.51.51.51.30.50.7
Bone volume1.22.03.11.41.61.8-1.0-1.3-1.31.7-1.51.71.6-1.5-1.61.41.61.51.51.40.60.4
Breakpoint value in progressive ratio session0.20.30.70.1-0.50.1-0.0-0.2-0.10.7-0.40.70.4-0.6-0.70.40.80.60.70.80.50.1
Number of licking bursts0.30.40.9-0.9-0.7-0.51.00.91.0-0.60.7-0.3-0.40.30.4-0.4-0.5-0.4-0.4-0.50.7-0.6
Context. condit. distance diff. score3.54.211.3-3.2-1.5-2.83.43.13.0-2.32.2-1.0-1.31.11.3-1.3-1.4-1.3-1.4-1.32.3-0.5
Locomotion velocity, session 10.90.91.91.20.01.4-1.0-0.9-1.11.1-1.00.90.9-1.0-1.01.01.01.01.01.2-0.10.3
Locomotion distance, session 12.83.57.82.51.22.8-2.2-2.0-2.22.2-2.11.51.7-1.6-1.81.71.81.81.82.0-0.70.3
Locomotion velocity, session 21.41.63.81.80.61.9-1.6-1.5-1.61.5-1.41.01.1-1.1-1.21.21.11.21.11.3-0.7-0.0
Locomotion distance, session 23.95.511.13.11.53.3-2.7-2.5-2.72.7-2.52.02.2-2.1-2.32.32.22.32.22.5-0.80.6
Locomotion velocity, session 31.61.82.6-1.3-1.5-1.50.71.21.0-1.61.4-1.6-1.51.51.5-1.4-1.6-1.5-1.6-1.4-0.6-0.7
Locomotion distance, session 30.80.81.2-1.1-0.9-1.00.81.11.1-1.11.0-0.8-0.80.90.9-1.0-0.9-0.8-0.9-0.90.1-0.8
Stereotopy head waving bouts, day 30.10.10.50.4-0.5-0.0-0.6-0.4-0.60.1-0.2-0.2-0.0-0.1-0.10.40.10.10.10.3-0.60.7
Stereotopy head waving duration, day 30.40.53.00.4-0.7-0.0-0.9-0.4-0.6-0.30.1-1.0-0.70.70.6-0.3-0.6-0.7-0.7-0.4-1.7-0.2
Locomotion velocity, session 73.43.712.6-3.2-0.8-2.83.63.02.9-1.82.0-0.4-0.90.60.9-0.8-1.0-0.9-0.9-0.93.00.2
Locomotion distance, session 71.51.910.7-2.10.0-1.52.72.02.1-0.60.90.80.2-0.5-0.20.30.20.30.20.13.30.6
Stereotopy head waving bouts, day 70.40.42.90.6-0.40.3-1.0-0.5-0.7-0.10.0-0.8-0.60.60.5-0.3-0.5-0.6-0.5-0.3-1.7-0.4
Stereotopy head waving duration, day 70.91.14.30.1-1.1-0.5-0.7-0.0-0.2-0.90.6-1.6-1.31.31.2-1.1-1.1-1.3-1.2-1.0-2.1-0.5
Locomotion velocity, session 80.60.71.5-0.8-1.2-0.60.81.10.9-0.80.9-0.8-0.80.80.8-0.7-0.8-0.7-0.8-0.60.0-1.0
Locomotion distance, session 80.20.21.1-0.4-0.10.10.80.70.5-0.00.00.50.4-0.5-0.40.40.30.50.30.61.1-0.1
Degree of sensitization distance1.61.69.7-1.11.0-0.62.01.01.10.4-0.01.51.0-1.3-1.01.11.01.01.00.83.11.1
Degree of sensitization stereotypy0.50.62.20.1-0.4-0.1-0.5-0.0-0.2-0.40.4-1.0-0.91.00.8-0.8-0.8-0.9-0.8-0.8-1.5-0.8
Conditioned locomotion0.30.31.0-0.9-1.0-0.80.90.80.8-0.50.4-0.0-0.20.00.0-0.20.1-0.0-0.10.11.00.2
Cocaine response after cond. corrected2.52.85.9-2.2-2.4-2.02.02.12.1-1.81.9-1.3-1.61.31.4-1.3-1.4-1.4-1.4-1.30.9-0.9
Cocaine response after cond. not corrected1.21.33.5-1.6-1.9-1.31.51.51.5-1.21.3-0.8-1.00.80.9-0.8-0.9-0.9-0.9-0.70.8-0.7
Cocaine response before conditioning2.42.84.02.02.02.0-1.7-2.0-1.91.9-1.91.61.7-1.6-1.61.61.71.71.61.6-0.21.0
Saline control response0.91.11.81.31.41.2-1.2-1.3-1.31.3-1.20.91.0-0.9-1.00.91.01.01.01.0-0.30.6
Bone: connectivity density1.62.55.70.41.30.30.1-0.5-0.41.1-1.32.01.8-2.0-1.91.71.92.01.91.82.32.4
Bone: cortical apparent density1.82.44.0-2.0-1.2-2.01.71.71.8-1.71.8-1.2-1.51.41.5-1.4-1.5-1.6-1.4-1.70.6-0.9
Bone: cortical area0.20.31.90.60.71.0-0.5-0.5-0.40.4-0.20.10.00.20.1-0.30.0-0.2-0.1-0.3-0.8-1.4
Bone: cortical porosity0.50.62.31.20.31.0-1.4-1.1-1.20.6-0.7-0.10.20.0-0.20.00.30.20.20.3-1.5-0.3
Bone: cortical porosity0.70.72.61.40.61.2-1.6-1.3-1.30.8-0.8-0.00.3-0.0-0.20.10.40.20.20.3-1.6-0.4
Bone: cortical thickness0.20.42.80.00.40.4-0.00.00.2-0.10.4-0.4-0.50.70.6-0.8-0.6-0.7-0.6-0.8-0.7-1.7
Bone: cortical thickness0.91.04.2-1.1-0.5-0.41.21.11.2-0.81.1-0.6-0.80.91.0-1.1-0.9-0.9-0.9-1.10.2-2.0
Bone: cortical tissue density2.12.84.5-2.1-1.3-2.11.81.91.9-1.81.9-1.4-1.61.51.6-1.5-1.7-1.7-1.6-1.80.6-1.0
Condit. Reinf. active minus inactive responses0.40.41.21.00.50.8-1.1-1.0-1.00.6-0.70.20.4-0.3-0.30.40.30.30.30.3-0.80.3
Condit. Reinf. active-inactive response ratio0.20.31.3-0.2-1.2-0.50.10.30.1-0.60.4-0.7-0.60.50.5-0.4-0.5-0.5-0.5-0.3-0.50.0
Condit. Reinf. active responses1.61.93.21.81.61.8-1.7-1.8-1.81.5-1.61.21.3-1.2-1.21.31.21.21.21.1-0.60.6
Condit. Reinf. inactive responses4.45.310.12.43.22.6-2.1-2.4-2.32.6-2.52.42.5-2.3-2.32.32.22.32.32.10.21.2
Incentive salience index mean1.01.23.51.71.01.5-1.9-1.7-1.71.1-1.10.40.6-0.5-0.60.70.50.50.50.5-1.40.2
Condit. Reinf. lever presses1.92.55.72.41.62.3-2.3-2.2-2.21.9-1.71.01.2-1.0-1.11.31.01.01.11.1-1.40.4
Condit. Reinf. active minus inactive responses0.50.60.90.80.50.9-0.4-0.6-0.50.9-0.80.80.8-0.8-0.90.61.00.90.90.90.30.3
Condit. Reinf. active-inactive response ratio0.40.40.8-0.6-0.9-0.50.60.70.8-0.70.7-0.7-0.60.60.6-0.6-0.5-0.5-0.6-0.5-0.1-0.5
Condit. Reinf. active responses0.71.01.50.81.01.0-0.5-0.7-0.61.1-1.11.21.2-1.1-1.20.91.21.21.21.10.70.6
Condit. Reinf. inactive responses2.32.84.41.21.81.3-0.7-1.2-1.21.8-1.72.12.0-2.0-2.01.81.91.92.01.91.31.5
Condit. Reinf. lever presses1.01.32.71.61.41.4-1.5-1.6-1.51.3-1.30.81.0-0.8-0.90.90.80.90.90.8-0.80.5
Condit. Reinf. lever reinforcers received0.50.71.00.81.00.9-0.6-0.7-0.60.9-0.91.01.0-0.8-1.00.61.01.01.00.90.30.4
Conditioned reinforcement - actives0.30.31.8-0.50.7-0.21.20.50.50.4-0.00.70.5-0.4-0.40.20.30.40.40.31.30.2
Conditioned reinforcement - inactives1.51.64.40.82.10.6-0.1-0.8-0.91.4-1.21.51.5-1.4-1.31.41.41.31.31.30.91.7
Conditioned locomotion0.20.31.3-0.80.6-0.91.10.70.6-0.00.30.20.10.10.0-0.3-0.0-0.0-0.0-0.20.8-0.1
Patch foraging indifference point 0 sec6.310.115.63.73.93.6-3.2-3.6-3.53.5-3.63.03.4-3.0-3.22.83.13.23.13.0-0.22.1
Patch foraging indifference point AUC4.24.96.2-2.2-2.4-1.81.92.32.2-2.32.4-2.3-2.42.32.3-2.2-2.3-2.4-2.3-2.2-0.6-2.5
Delay disc. indifference point, 0s delay2.83.04.01.81.61.9-1.9-1.7-1.92.0-1.91.71.8-1.8-1.82.01.61.71.81.90.11.2
Delay disc. indifference point, 16s delay0.30.32.2-0.60.0-0.1-0.20.40.3-0.40.5-0.4-0.50.60.6-0.6-0.1-0.6-0.5-0.9-0.2-1.5
Delay disc. indifference point, 2s delay1.71.94.71.90.71.9-2.2-1.7-1.91.7-1.50.91.0-1.0-1.01.21.11.01.01.1-1.10.1
Delay disc. indifference point, 24s delay0.40.42.1-0.5-0.7-0.1-0.10.40.2-0.40.6-0.6-0.80.70.7-0.5-0.3-0.8-0.6-0.8-0.5-1.4
Delay disc. indifference point, 4s delay0.60.61.5-0.1-0.60.0-0.70.0-0.1-0.60.5-0.9-0.90.90.9-0.8-0.6-1.0-0.9-1.0-1.2-1.2
Delay disc. indifference point, 8s delay0.50.51.9-0.40.4-0.4-0.30.10.4-0.40.4-0.5-0.60.80.7-1.1-0.5-0.8-0.6-1.2-0.5-1.4
Indifference point function ln k1.72.44.61.81.81.6-2.2-1.9-1.81.6-1.81.41.6-1.4-1.41.31.51.61.41.3-0.21.2
Indifference point function log k1.72.44.61.81.81.6-2.2-1.9-1.81.6-1.81.41.6-1.4-1.41.31.51.61.41.3-0.21.2
Patch foraging total patch changes 0 sec5.69.114.33.63.83.5-3.2-3.5-3.43.3-3.42.83.1-2.7-2.92.62.93.02.82.8-0.51.8
Patch foraging total patch changes 12 sec0.81.12.11.31.11.5-1.0-1.2-1.11.3-1.21.01.0-0.9-1.00.91.01.01.00.9-0.3-0.0
Patch foraging total patch changes 18 sec0.20.21.20.31.10.6-0.0-0.3-0.30.5-0.40.60.6-0.5-0.40.40.40.50.40.40.3-0.2
Patch foraging total patch changes 24 sec1.62.04.72.01.52.2-1.6-1.8-1.71.6-1.61.11.3-1.0-1.20.91.21.21.21.2-0.9-0.0
Patch foraging total patch changes 6 sec0.20.30.90.60.90.6-0.1-0.5-0.60.7-0.50.50.6-0.5-0.50.50.50.50.50.40.00.4
Patch foraging time to switch 0 sec0.71.21.90.60.50.6-0.1-0.6-0.61.1-1.01.41.2-1.4-1.31.31.31.21.31.21.11.3
Patch foraging water rate 0 sec0.20.31.50.60.10.6-0.9-0.4-0.5-0.0-0.1-0.5-0.20.40.3-0.3-0.4-0.2-0.4-0.2-1.2-0.8
Patch foraging water rate 12 sec0.20.31.50.90.40.7-1.2-0.9-0.90.4-0.5-0.10.10.1-0.1-0.00.10.10.00.1-1.1-0.2
Patch foraging water rate 18 sec2.02.74.8-0.5-0.9-0.7-0.40.50.5-1.51.3-2.1-1.82.22.0-2.2-2.0-1.9-2.0-2.1-2.2-2.1
Patch foraging water rate 24 sec0.81.11.7-1.2-0.5-1.30.71.00.9-1.31.2-1.1-1.01.21.2-1.0-1.2-1.1-1.3-1.2-0.1-0.8
Patch foraging water rate 6 sec0.60.95.00.90.10.8-1.7-0.9-1.0-0.0-0.1-0.9-0.50.80.6-0.5-0.6-0.6-0.6-0.6-2.2-1.3
Seeking ratio, delayed vs. immediate footshock2.22.54.11.51.81.0-1.0-1.5-1.61.8-1.71.51.7-1.6-1.61.81.71.61.72.00.21.8
Distance traveled before self-admin0.30.31.90.5-0.40.2-0.7-0.5-0.60.2-0.1-0.5-0.30.40.4-0.3-0.3-0.3-0.3-0.2-1.4-0.8
Distance traveled after self-admin0.60.61.8-0.2-0.9-0.2-0.50.30.1-0.50.6-1.0-0.90.90.9-0.6-0.8-0.9-0.8-1.0-1.2-1.3
Extensor digitorum longus weight4.316.933.5-1.0-5.2-1.4-0.41.31.1-3.53.3-5.4-4.85.14.6-4.7-4.6-4.6-4.7-4.3-5.8-5.0
Bone: elastic displacement2.22.54.12.01.52.0-1.9-1.8-1.91.7-1.81.31.5-1.5-1.51.71.61.51.51.6-0.50.7
Bone: elastic work3.64.69.52.92.33.1-2.8-2.7-2.72.3-2.41.61.9-1.6-1.81.81.91.91.81.8-1.20.3
Bone: endosteal estimation0.20.40.80.90.50.9-0.8-0.8-0.70.7-0.70.60.6-0.6-0.60.60.70.60.50.5-0.20.2
Bone: endosteal perimeter1.02.13.51.81.11.9-1.5-1.6-1.61.6-1.61.31.4-1.4-1.51.51.61.41.41.5-0.30.7
Epididymis fat weight0.30.71.90.01.30.20.2-0.2-0.30.6-0.71.21.0-1.0-1.00.91.00.91.00.51.41.1
Delta time in closed arm before/after self-admin0.10.10.8-0.10.6-0.2-0.2-0.0-0.20.1-0.30.30.4-0.4-0.40.40.30.30.30.30.40.9
Delta time in open arm before/after self-admin0.30.21.6-0.6-0.3-0.71.30.50.7-0.20.20.20.1-0.2-0.10.00.20.20.20.21.00.4
Diff in mean of infusions in LGA sessions0.30.32.10.7-0.40.4-1.5-0.7-0.80.1-0.4-0.2-0.1-0.0-0.10.20.10.00.10.2-1.00.5
Delay discount exponential model param0.40.42.50.0-0.1-0.20.70.10.20.2-0.30.50.5-0.7-0.60.70.30.70.60.91.01.6
Extinction: sum of active levers before priming1.01.02.20.21.40.50.2-0.1-0.10.8-0.71.31.1-1.2-1.01.31.11.11.11.11.50.8
Active lever presses in extinction session 60.20.20.7-0.8-0.1-0.60.60.70.7-0.30.50.0-0.1-0.00.20.1-0.2-0.2-0.1-0.30.80.1
Bone: final force0.10.10.90.40.30.6-0.5-0.4-0.20.3-0.1-0.1-0.10.20.2-0.2-0.1-0.2-0.1-0.3-0.6-0.9
Bone: final moment0.20.41.20.90.81.1-1.0-0.9-0.70.7-0.50.20.3-0.1-0.10.10.20.10.1-0.1-0.8-0.8
Food consumed during 24 hour testing period0.30.42.80.61.70.4-0.9-0.8-0.70.3-0.4-0.10.20.20.2-0.0-0.2-0.2-0.1-0.3-1.1-0.5
Glucose1.92.94.1-2.0-1.0-1.81.81.82.0-1.91.9-1.4-1.61.71.7-2.0-1.7-1.7-1.7-1.80.3-1.5
Heart weight0.10.11.40.11.2-0.1-0.3-0.3-0.3-0.0-0.20.00.20.00.0-0.0-0.0-0.0-0.0-0.1-0.20.3
Delay discount hyperbolic model param0.40.42.2-0.3-0.1-0.41.10.40.50.0-0.10.50.5-0.6-0.60.60.20.60.50.81.21.5
Intermittent access intake day 1-15 change0.20.20.70.30.80.4-0.3-0.3-0.10.3-0.50.50.5-0.4-0.50.20.50.50.50.30.40.8
Intermittent access intake escalation0.00.00.10.20.30.3-0.2-0.10.10.1-0.20.20.2-0.1-0.2-0.00.30.20.20.10.20.3
Intermittent access intake escalation 20.10.10.40.30.40.3-0.5-0.2-0.10.1-0.20.10.2-0.2-0.20.20.30.20.20.20.00.7
Intermitt. access day 1 inactive lever presses0.50.54.2-0.6-0.3-1.30.60.40.30.10.00.30.3-0.5-0.40.50.40.40.40.71.12.1
Intermitt. access day 15 inactive lever presses0.10.21.1-0.3-0.1-1.0-0.10.10.1-0.40.2-0.4-0.20.30.3-0.2-0.2-0.3-0.3-0.2-0.30.8
Intermitt. access escalation Index0.10.10.5-0.1-0.5-0.30.70.20.20.30.2-0.0-0.1-0.10.00.3-0.1-0.1-0.00.40.1-0.1
Intermittent access day 1 total infusions1.11.32.7-1.30.0-1.21.21.11.0-1.11.1-1.0-1.01.21.2-1.3-1.3-1.2-1.2-1.1-0.3-1.6
Intermittent access day 15 total infusions0.60.61.3-1.10.0-1.11.11.01.1-0.80.8-0.5-0.60.70.7-0.9-0.7-0.6-0.7-0.70.4-0.6
Intermittent access terminal intake (last 3 days)1.61.82.9-1.4-0.5-1.21.41.31.5-1.51.4-1.2-1.31.51.4-1.7-1.4-1.4-1.4-1.5-0.2-1.4
Intermittent access total infusions1.21.43.0-1.6-0.1-1.41.71.51.5-1.21.3-0.7-0.91.01.0-1.3-1.1-1.0-1.1-1.10.6-1.1
Intermittent access day 1 locomotion0.10.11.5-0.31.2-0.30.3-0.0-0.10.3-0.20.40.4-0.1-0.2-0.00.10.20.10.00.2-0.4
Intermittent access day 15 total locomotion0.50.61.7-1.20.7-1.30.80.80.8-0.90.7-0.4-0.40.60.7-0.7-0.6-0.7-0.7-0.90.3-0.3
Intermittent access total locomotion0.10.11.0-0.61.0-0.80.40.30.2-0.20.10.00.00.20.2-0.5-0.2-0.2-0.2-0.40.1-0.2
Intermittent access standard deviation0.30.30.60.10.50.3-0.6-0.00.2-0.70.3-0.6-0.50.70.6-0.7-0.6-0.6-0.7-0.7-0.8-0.7
Left kidney weight0.41.13.30.10.8-0.6-0.1-0.2-0.1-0.90.5-1.4-1.01.51.3-1.5-1.3-1.3-1.3-1.4-1.8-0.4
Right kidney weight0.72.17.61.92.81.3-1.7-2.0-1.91.2-1.60.91.3-0.8-1.00.70.91.01.00.9-0.91.6
Cocaine induced anxiety0.91.02.91.30.90.5-1.3-1.6-1.71.2-1.20.50.8-0.6-0.70.70.60.70.70.8-1.20.5
Post-drug Anxiety2.32.53.71.01.50.6-0.8-1.3-1.21.6-1.71.91.8-1.9-1.91.71.81.91.91.81.21.9
Baseline Anxiety1.41.52.90.61.21.2-0.1-0.4-0.21.0-1.01.61.4-1.5-1.41.41.41.41.41.31.71.1
Tail length0.82.36.91.22.61.3-0.8-1.3-1.41.5-1.61.71.8-1.6-1.51.61.51.61.51.40.71.4
Length with tail0.52.04.01.91.71.4-2.0-1.9-2.01.4-1.60.91.2-1.0-1.11.21.01.11.11.0-1.01.3
Length without tail0.51.06.81.2-0.60.5-1.9-1.2-1.2-0.0-0.3-1.0-0.60.80.6-0.5-0.5-0.6-0.6-0.5-2.6-0.3
Times rat made contact with spout0.10.20.4-0.50.6-0.20.50.50.6-0.30.4-0.1-0.20.30.3-0.4-0.3-0.3-0.3-0.50.3-0.6
Lifetime Intake0.60.61.6-1.20.4-1.11.21.00.9-0.70.8-0.4-0.50.70.7-0.8-0.8-0.7-0.7-0.70.4-0.8
Liver weight, left3.04.87.9-1.1-1.5-1.60.31.01.1-2.32.0-2.8-2.52.82.7-2.7-2.8-2.6-2.7-2.8-2.3-1.7
Liver weight, right1.42.33.8-0.6-1.3-0.70.20.80.9-1.41.4-1.9-1.81.91.8-1.8-1.8-1.8-1.8-1.8-1.7-1.9
Locomotor activity2.94.612.03.21.92.9-3.5-3.2-3.22.2-2.41.01.4-1.1-1.41.31.51.21.41.0-2.40.4
Locomotor testing distance6.611.016.54.13.23.9-3.9-4.0-3.93.7-3.83.03.2-3.0-3.23.13.33.23.33.0-0.81.9
Locomotor testing rearing11.017.024.34.93.74.5-4.3-4.7-4.74.6-4.63.74.1-3.9-4.24.04.24.14.24.3-0.63.1
Locomotion in novel chamber0.10.10.5-0.10.70.20.00.10.1-0.10.2-0.1-0.10.40.4-0.5-0.5-0.3-0.4-0.6-0.2-0.7
Locomotion in novel chamber post-restriction0.60.72.6-0.5-0.8-0.50.10.60.4-0.70.7-1.0-0.81.00.9-0.9-1.0-0.8-0.9-0.8-1.0-1.6
Fecal boli incidents, locomotor time 11.31.43.8-0.40.0-0.4-0.20.10.6-0.80.9-1.2-1.31.61.4-1.9-0.8-1.6-1.2-1.9-1.4-1.9
Change in fecal boli incidents, locomotor task0.40.41.6-0.8-1.0-1.30.70.50.2-0.50.3-0.0-0.0-0.3-0.10.7-0.40.3-0.10.40.81.2
Time >=10cm from walls, locomotor time 11.11.12.31.11.51.0-0.8-1.0-0.71.0-1.21.21.3-1.0-1.00.91.21.31.00.90.51.3
Bouts of movement, locomotor time 10.80.82.4-0.2-1.60.00.50.80.8-0.90.9-1.2-1.11.10.9-1.3-0.8-0.9-0.9-0.7-0.8-0.7
Total resting periods, locomotor time 11.82.04.7-1.0-2.2-0.71.21.51.5-1.51.5-1.6-1.61.61.4-1.7-1.3-1.4-1.4-1.2-0.5-1.1
Rest time, locomotor task time 12.22.45.6-1.4-2.4-1.11.21.71.6-1.61.7-1.7-1.71.61.6-1.7-1.6-1.4-1.6-1.2-0.4-1.6
Distance moved, locomotor task time 11.41.52.21.11.51.1-0.7-1.1-1.01.2-1.31.51.4-1.4-1.41.31.31.31.31.10.71.2
Vertical activity count, locomotor time 12.52.65.42.31.42.2-2.1-2.2-2.31.8-1.81.11.3-1.2-1.31.61.11.21.21.3-1.10.5
Time >=10cm from walls, locomotor time 20.10.10.20.2-0.3-0.2-0.4-0.2-0.3-0.2-0.0-0.2-0.10.10.20.1-0.3-0.2-0.3-0.0-0.50.3
Bouts of movement, locomotor time 21.61.84.9-1.1-2.2-0.70.51.31.1-1.61.4-1.5-1.51.31.4-1.1-1.6-1.4-1.5-1.1-0.4-1.3
Total resting periods, locomotor time 23.43.67.0-1.7-2.6-1.41.01.91.7-2.22.1-2.1-2.22.02.0-1.8-2.2-2.1-2.1-1.8-0.5-1.8
Rest time, locomotor task time 28.49.714.0-2.8-2.4-2.22.02.92.9-3.33.3-3.3-3.33.53.5-3.7-3.4-3.3-3.4-3.6-1.0-3.6
Distance moved, locomotor task time 24.55.27.02.42.32.2-1.9-2.3-2.32.4-2.52.42.4-2.5-2.42.62.12.32.32.40.51.9
Vertical activity count, locomotor time 24.14.47.82.81.72.5-2.4-2.6-2.82.5-2.41.81.9-1.9-1.92.41.61.71.82.2-1.00.8
Light reinforcement 10.40.72.7-0.31.4-0.10.40.20.30.4-0.41.10.8-0.9-0.80.80.70.60.90.71.70.9
Light reinforcement 21.62.15.3-2.3-0.7-1.92.22.12.0-1.61.6-0.8-1.10.91.1-1.0-1.1-1.2-1.0-1.31.4-0.6
Bone: marrow area0.20.50.90.90.60.9-0.8-0.8-0.70.8-0.80.70.7-0.6-0.60.70.80.70.60.6-0.10.3
Bone: maximum diameter0.20.42.50.2-0.20.5-0.20.00.1-0.30.4-0.6-0.60.70.6-0.7-0.4-0.6-0.7-0.6-1.1-1.6
Bone: maximum force0.30.52.30.90.41.3-1.0-0.8-0.60.6-0.3-0.1-0.00.30.1-0.3-0.1-0.2-0.1-0.4-1.2-1.5
Bone: maximum moment0.50.93.11.51.01.8-1.5-1.4-1.21.0-0.80.30.4-0.1-0.20.10.30.20.2-0.1-1.4-1.3
Mean time between licks in bursts2.33.25.30.71.60.8-0.2-0.8-0.81.4-1.62.32.1-2.3-2.22.12.12.22.12.22.12.1
Mean num. licks in bursts0.10.11.00.51.00.3-0.5-0.5-0.50.3-0.30.10.2-0.1-0.10.10.10.10.10.1-0.40.0
Cd content in liver0.10.20.60.30.80.2-0.2-0.4-0.30.4-0.40.50.4-0.4-0.40.40.40.40.40.20.30.6
Co content in liver2.22.65.3-1.5-2.3-1.60.91.41.2-1.61.7-1.8-1.91.71.7-1.6-1.6-1.7-1.7-1.5-0.9-1.9
Cu content in liver1.01.22.8-1.1-1.2-1.70.50.80.7-1.11.0-1.3-1.21.21.1-1.1-1.1-1.2-1.1-1.1-0.7-0.7
Fe content in liver0.30.42.2-0.30.9-0.50.40.20.2-0.1-0.20.50.5-0.6-0.50.50.50.50.50.41.21.5
K content in liver0.20.21.1-0.30.2-0.10.50.40.20.1-0.10.60.5-0.6-0.50.60.40.50.40.61.00.5
Mg content in liver0.20.20.7-0.30.4-0.10.40.30.20.1-0.20.50.5-0.5-0.50.50.40.50.40.60.90.4
Mn content in liver1.72.03.40.51.50.7-0.1-0.5-0.71.3-1.21.81.7-1.8-1.71.81.61.71.61.81.51.2
Na content in liver2.52.69.52.61.42.2-3.1-2.5-2.51.4-1.60.20.8-0.4-0.60.60.60.70.60.7-2.6-0.0
Rb content in liver0.50.62.0-1.2-0.3-1.41.21.01.1-1.00.8-0.3-0.40.40.5-0.4-0.5-0.4-0.5-0.50.90.5
Se content in liver4.85.97.62.42.21.8-2.3-2.6-2.72.7-2.82.32.5-2.5-2.62.62.62.52.62.7-0.02.2
Sr content in liver0.90.81.80.30.50.0-0.2-0.4-0.50.8-0.81.01.0-1.1-1.11.11.11.11.11.30.81.3
Zn content in liver0.80.83.31.30.60.5-1.8-1.5-1.60.9-1.00.10.4-0.2-0.40.40.40.40.40.4-1.60.2
Bone: minimum diameter0.51.03.01.51.11.7-1.5-1.4-1.31.1-0.90.40.5-0.3-0.40.40.60.30.40.2-1.3-0.9
Time in familiar zone, hab. session 10.10.10.3-0.1-0.10.30.30.20.10.3-0.00.40.2-0.3-0.30.30.20.30.30.30.5-0.4
Time in novel zone, hab. session 12.02.03.0-1.0-1.4-1.40.50.90.9-1.61.4-1.7-1.71.61.6-1.6-1.6-1.7-1.6-1.7-1.0-0.9
Total zone transitions, hab. session 10.60.93.41.40.61.8-1.3-1.1-1.31.1-0.90.50.6-0.5-0.60.70.50.60.50.6-1.0-0.9
Total locomotion distance, hab. session 11.62.35.41.91.42.3-1.6-1.6-1.81.9-1.61.31.4-1.3-1.41.41.41.41.41.4-0.5-0.1
Locomotion velocity, hab. session 13.65.09.92.82.13.1-2.3-2.4-2.62.7-2.42.12.2-2.1-2.22.22.12.22.22.2-0.40.5
Time in familiar zone, hab. session 21.21.23.8-1.5-1.9-1.31.41.41.5-1.11.2-0.7-1.00.70.8-0.8-0.8-0.8-0.8-0.90.7-0.5
Time in novel zone, hab. session 20.70.71.51.21.21.2-1.1-1.1-1.20.9-0.90.60.7-0.6-0.60.60.60.60.60.7-0.60.1
Total zone transitions, hab. session 20.91.13.31.8-0.01.8-1.8-1.4-1.61.0-1.00.20.4-0.3-0.50.50.40.50.40.7-1.7-0.6
Total locomotion distance, hab. session 20.70.92.51.40.21.6-1.3-1.1-1.31.1-0.90.60.7-0.6-0.70.80.70.70.70.9-0.8-0.3
Locomotion velocity, hab. session 20.81.13.61.60.21.9-1.6-1.3-1.51.2-1.00.50.7-0.6-0.70.70.70.70.70.9-1.2-0.6
Novel to familiar place preference ratio0.70.81.41.11.11.2-0.9-1.1-0.91.1-0.90.90.9-0.8-0.80.70.80.80.80.7-0.10.0
Novelty place preference0.91.01.61.11.11.2-1.0-1.2-1.01.2-1.11.11.0-0.9-1.00.81.01.01.00.80.00.3
Time in novel zone, NPP test0.91.01.61.20.91.3-1.0-1.2-1.11.2-1.11.01.0-0.9-1.00.71.01.01.00.9-0.10.2
Total zone transitions, NPP test1.92.75.11.91.32.3-1.6-1.6-1.81.9-1.81.51.7-1.6-1.71.61.71.71.61.9-0.10.4
Total locomotion distance, NPP test5.37.29.92.42.62.8-1.7-2.1-2.33.0-2.83.03.0-3.0-3.02.93.03.03.03.11.21.7
Locomotion velocity, NPP test4.15.87.72.12.52.6-1.5-1.9-2.02.7-2.52.82.7-2.7-2.72.82.62.72.72.81.21.4
Intraocular pressure1.11.62.60.90.91.0-0.6-0.8-0.81.2-1.21.51.4-1.6-1.51.51.41.51.51.61.01.4
Delta distance traveled before/after self-admin1.01.02.5-1.0-1.6-0.80.31.00.8-1.21.1-1.2-1.21.01.1-0.8-1.1-1.1-1.1-1.1-0.4-0.7
Delta ambulatory time before/after self-admin0.60.71.9-0.6-1.4-0.4-0.20.70.4-0.90.8-1.0-1.10.80.9-0.5-0.9-1.0-0.9-0.9-0.6-0.8
Parametrial fat weight1.32.57.4-0.01.20.60.4-0.10.01.3-1.12.31.8-2.1-1.91.81.91.92.01.62.71.0
Pavlov. Cond. lever latency0.50.71.6-1.2-1.3-1.01.21.21.2-0.90.8-0.4-0.50.40.4-0.7-0.3-0.3-0.4-0.40.9-0.3
Pavlov. Cond. magazine entry latency0.10.10.70.10.9-0.3-0.2-0.2-0.2-0.1-0.1-0.1-0.00.20.2-0.1-0.2-0.2-0.2-0.2-0.30.6
Pavlov. Cond. change in total contacts0.80.94.61.40.71.2-1.7-1.3-1.40.5-0.5-0.4-0.20.40.3-0.2-0.3-0.4-0.3-0.3-2.1-0.8
Pavlov. Cond. index score0.20.31.30.81.00.4-1.0-0.8-0.80.3-0.4-0.20.00.20.20.0-0.2-0.2-0.2-0.1-1.10.2
Pavlov. Cond. latency score0.30.41.40.91.20.6-1.0-1.0-0.90.5-0.50.00.20.0-0.00.2-0.0-0.00.00.0-1.00.3
Pavlov. Cond. lever contacts0.30.41.60.91.30.5-1.0-1.0-1.00.5-0.60.00.20.0-0.10.2-0.00.00.10.1-1.00.3
Pavlov. Cond. magazine entry number0.20.31.3-0.3-0.40.00.60.40.30.2-0.10.60.4-0.7-0.60.50.60.60.60.51.20.1
Pavlov. Cond. intertrial magazine entries1.62.03.11.61.41.8-1.5-1.6-1.61.6-1.61.41.4-1.4-1.41.51.41.41.41.3-0.20.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.70.70.80.3-1.0-0.7-0.80.1-0.2-0.4-0.20.40.3-0.2-0.4-0.4-0.3-0.3-1.3-0.0
Pavlov. Cond. response bias0.40.41.50.10.5-0.3-0.5-0.2-0.2-0.50.3-0.8-0.60.90.8-0.8-0.9-0.8-0.8-0.8-1.2-0.2
Pavlov. Cond. lever latency0.40.53.3-0.9-0.4-0.51.41.01.0-0.00.30.60.2-0.5-0.30.30.40.30.30.41.80.3
Pavlov. Cond. magazine entry latency0.40.41.60.91.20.8-1.0-1.0-1.00.5-0.70.20.4-0.3-0.30.50.30.20.30.2-0.90.1
Pavlov. Cond. change in total contacts0.71.05.60.8-0.10.4-1.5-0.8-0.8-0.40.0-1.1-0.71.00.8-0.9-0.8-0.8-0.9-1.0-2.4-0.8
Pavlov. Cond. index score0.50.73.31.20.70.8-1.6-1.2-1.30.4-0.6-0.30.10.20.00.1-0.1-0.1-0.1-0.1-1.8-0.1
Pavlov. Cond. latency score0.60.82.91.41.01.0-1.7-1.4-1.50.6-0.9-0.00.4-0.1-0.20.40.20.20.20.2-1.60.2
Pavlov. Cond. lever contacts0.71.04.01.60.81.2-1.9-1.6-1.60.7-0.8-0.20.20.0-0.10.30.00.10.10.0-2.0-0.2
Pavlov. Cond. magazine entry number0.60.71.7-1.1-1.3-1.21.11.11.2-0.80.9-0.6-0.70.60.6-0.8-0.6-0.5-0.6-0.50.6-0.1
Pavlov. Cond. intertrial magazine entries4.15.39.11.02.11.30.2-0.9-0.82.4-2.03.02.7-2.8-2.72.52.82.72.82.82.92.4
Pavlov. Cond. lever-magazine prob. diff.0.40.63.21.10.50.8-1.4-1.1-1.20.2-0.5-0.4-0.10.30.20.0-0.2-0.2-0.2-0.2-1.8-0.2
Pavlov. Cond. response bias0.81.14.31.70.91.4-2.0-1.6-1.70.8-0.9-0.10.3-0.0-0.10.40.10.10.10.1-2.1-0.4
Time in closed arm before self-admin0.30.31.3-0.3-1.2-0.5-0.30.20.1-0.50.5-0.7-0.60.60.5-0.5-0.6-0.5-0.5-0.4-0.7-0.5
Time in closed arm after self-admin0.20.20.90.3-0.30.1-0.9-0.4-0.80.4-0.40.10.2-0.4-0.30.70.20.20.30.5-0.40.6
Time in open arm before self-admin0.40.41.90.90.31.4-1.2-0.7-0.70.8-0.60.60.5-0.4-0.50.30.60.50.50.2-0.2-0.2
Time in open arm after self-admin0.10.20.9-0.40.1-0.30.90.50.6-0.10.10.30.2-0.2-0.10.00.40.20.20.10.90.4
Bone: periosteal estimation0.20.41.30.90.71.2-0.8-0.8-0.60.7-0.60.50.4-0.3-0.30.30.50.30.30.2-0.5-0.7
Bone: periosteal perimeter0.61.02.51.30.91.6-1.0-1.1-1.11.2-1.10.90.9-0.9-0.90.91.10.90.90.9-0.3-0.0
Bone: post-yield work1.92.66.9-1.8-0.9-1.01.71.71.8-1.31.8-1.1-1.51.51.6-1.7-1.6-1.7-1.6-1.90.3-2.6
Progressive ratio test 1 active lever presses3.13.34.8-2.2-1.2-2.02.12.02.1-1.92.0-1.6-1.71.81.8-1.9-1.8-1.8-1.8-1.80.1-1.9
Progressive ratio test 1 breakpoint3.33.55.2-2.3-1.3-2.02.22.12.3-2.02.1-1.6-1.71.81.9-2.0-1.8-1.8-1.9-1.80.3-1.9
Progressive ratio test 1 inactive lever presses0.20.31.2-0.60.2-0.80.50.30.40.1-0.00.50.4-0.5-0.40.50.40.30.40.51.10.7
Progressive ratio test 2 active lever presses2.12.33.6-1.9-0.1-1.91.61.71.7-1.71.6-1.3-1.31.51.6-1.6-1.7-1.6-1.6-1.70.2-1.0
Progressive ratio test 2 breakpoint1.61.82.5-1.60.3-1.61.31.41.4-1.51.4-1.2-1.21.41.5-1.4-1.6-1.5-1.5-1.6-0.0-0.8
Progressive ratio test 2 inactive lever presses0.40.42.1-1.00.8-1.40.80.60.7-0.60.5-0.3-0.30.60.6-0.6-0.6-0.5-0.6-0.60.10.2
Incentive Sensitization - Responses0.30.31.8-0.01.3-0.3-0.4-0.10.0-0.30.1-0.4-0.20.60.5-0.5-0.6-0.5-0.6-0.7-0.60.1
Incentive Sensitization - Breakpoint0.20.22.40.11.5-0.2-0.5-0.1-0.1-0.1-0.0-0.2-0.10.40.4-0.4-0.5-0.4-0.4-0.6-0.60.2
Sum of active levers in priming session hrs 5-60.50.52.1-1.2-0.6-0.71.11.11.1-0.60.70.1-0.3-0.00.20.1-0.0-0.2-0.1-0.31.4-0.1
Progressive ratio0.20.21.20.50.00.5-0.6-0.3-0.4-0.10.1-0.6-0.40.40.4-0.2-0.2-0.4-0.4-0.4-1.1-0.5
Food seeking constrained by brief footshock2.93.68.0-2.3-2.8-2.02.22.62.2-2.32.2-1.8-1.91.51.7-1.3-1.7-1.7-1.7-1.20.7-0.3
Seeking ratio, punishment vs. effort0.91.22.2-1.5-1.5-1.31.41.51.5-1.31.2-0.7-0.90.80.8-0.9-1.0-0.8-0.8-0.60.8-0.1
Retroperitoneal fat weight0.10.32.3-0.80.3-0.50.80.60.5-0.10.10.60.3-0.5-0.40.50.40.30.40.11.50.5
Reaction time number correct0.20.31.7-0.7-1.3-0.80.40.70.6-0.60.6-0.4-0.40.30.3-0.2-0.4-0.3-0.3-0.10.40.1
Reaction time mean minus median0.30.41.10.90.10.5-1.0-0.9-0.90.5-0.70.30.4-0.5-0.50.70.40.50.50.6-0.50.8
Reaction time mean minus median AUC0.20.20.50.50.10.2-0.7-0.5-0.60.3-0.40.20.3-0.4-0.30.70.20.30.30.6-0.20.7
Reaction time num false alarms0.60.91.81.10.61.1-1.4-1.0-1.11.0-1.00.80.9-0.9-0.91.10.90.90.90.9-0.20.5
Reaction time num false alarms AUC0.30.41.80.80.50.8-1.3-0.8-0.90.7-0.60.40.5-0.5-0.40.70.50.40.50.4-0.4-0.0
Reaction time trials correct on left0.20.31.7-0.7-1.3-0.80.40.70.6-0.60.6-0.4-0.40.30.3-0.2-0.4-0.3-0.3-0.10.40.1
Reaction time trials on left0.20.31.6-0.7-1.3-0.80.50.70.6-0.50.6-0.3-0.40.20.3-0.1-0.3-0.3-0.3-0.00.50.2
Reaction time mean0.00.10.50.0-0.2-0.4-0.1-0.1-0.3-0.10.0-0.3-0.20.10.10.2-0.1-0.2-0.1-0.0-0.30.7
Reaction time mean AUC0.10.10.60.3-0.2-0.2-0.4-0.4-0.50.1-0.2-0.2-0.1-0.00.00.3-0.0-0.1-0.00.1-0.50.8
Median of all reaction times0.10.10.5-0.3-0.3-0.70.30.20.0-0.30.3-0.5-0.40.30.40.0-0.3-0.5-0.3-0.3-0.20.7
Reaction time omissions1.11.53.10.50.80.40.0-0.6-0.51.1-1.01.61.3-1.6-1.41.61.51.41.41.41.61.8
Reaction time false alarm rate0.30.41.10.71.00.8-1.0-0.8-0.70.7-0.60.50.5-0.4-0.40.50.50.40.40.3-0.3-0.1
Reaction time premature initiation rate0.40.61.3-0.4-0.9-0.60.00.50.6-0.90.6-1.0-0.81.00.8-1.1-0.9-0.7-0.8-0.7-0.7-0.4
Reaction time premature initiations0.71.02.6-0.8-1.6-1.00.30.90.9-1.11.0-1.1-1.01.11.0-1.2-1.1-1.0-1.0-0.8-0.4-0.5
Std. dev. reaction times0.00.00.20.1-0.1-0.2-0.2-0.2-0.3-0.1-0.1-0.1-0.10.00.10.2-0.1-0.1-0.10.0-0.20.5
Reaction time trials completed0.20.31.6-0.7-1.3-0.80.50.70.6-0.50.6-0.3-0.40.20.3-0.1-0.3-0.3-0.3-0.00.50.2
Reaction time trials AUC0.20.31.4-0.7-1.2-0.80.40.60.6-0.50.5-0.3-0.30.20.3-0.1-0.3-0.3-0.3-0.00.50.1
Run reversals in cocaine runway, females0.40.41.6-0.11.30.20.60.20.00.4-0.40.80.8-0.7-0.70.50.60.70.60.41.00.2
Run reversals in cocaine runway, males3.43.37.7-0.5-1.0-0.9-0.20.50.6-1.51.4-2.4-2.02.42.2-2.2-2.3-2.1-2.2-2.0-2.8-2.3
Latency to leave start box in cocaine runway0.70.81.8-0.6-1.3-1.40.40.50.3-0.80.8-1.2-1.01.01.0-0.7-1.0-0.8-1.0-0.4-1.0-0.3
Latency to leave start box in cocaine runway, F1.21.32.9-0.4-1.7-1.20.10.40.2-1.01.0-1.6-1.41.41.4-0.9-1.5-1.3-1.4-0.8-1.7-0.5
Latency to leave start box in cocaine runway, M0.50.51.00.20.7-0.10.1-0.2-0.40.6-0.70.80.9-0.8-0.90.51.01.00.80.90.80.9
Std. dev. time between licks in bursts7.58.911.72.82.62.9-2.2-2.7-2.73.1-3.23.33.4-3.3-3.43.13.43.43.33.31.22.5
Total sessions with >9 infusions0.20.21.1-0.60.1-0.70.70.50.30.10.10.40.3-0.4-0.30.40.30.30.30.51.00.6
Short access day 1 total inactive lever presses1.71.92.8-1.60.4-1.61.61.41.3-1.41.4-1.2-1.11.51.4-1.7-1.4-1.4-1.4-1.6-0.1-1.3
Short access day 10 total inactive lever presses0.30.31.3-0.6-0.3-0.90.80.50.60.10.20.40.2-0.4-0.30.50.40.30.40.51.20.9
Short access day 1 total infusions1.11.13.4-1.6-0.6-1.91.51.31.1-1.11.1-0.8-0.90.80.9-0.8-1.0-0.9-1.0-0.80.4-0.3
Short access day 10 total infusions0.30.32.70.00.7-0.0-0.1-0.1-0.10.10.2-0.4-0.30.60.5-0.6-0.5-0.5-0.5-0.5-1.0-1.6
Short access total infusions0.20.30.5-0.60.7-0.70.50.40.3-0.40.4-0.4-0.30.50.5-0.5-0.6-0.5-0.6-0.5-0.2-0.7
Short access day 1 locomotion0.20.20.70.60.40.2-0.8-0.6-0.60.4-0.40.00.2-0.1-0.10.30.10.10.10.4-0.70.3
Short access day 10 total locomotion0.60.61.90.41.40.2-0.5-0.7-0.80.8-0.80.90.9-0.8-0.80.90.90.80.80.60.30.8
Short access total locomotion0.70.71.90.61.40.3-0.6-0.8-0.80.9-0.90.91.0-0.9-0.90.80.90.90.90.80.30.9
One hour access (0.3 mA shock)0.20.31.3-0.30.70.00.50.40.5-0.10.4-0.2-0.30.50.5-0.7-0.5-0.5-0.5-0.5-0.1-1.1
Compulsive drug intake0.60.61.70.80.30.7-0.2-0.6-0.81.3-0.70.90.7-0.8-0.81.00.80.80.81.00.20.3
One hour access (shock baseline)0.60.71.3-0.8-0.1-0.60.70.90.8-0.90.9-0.8-0.81.00.9-1.2-1.0-0.9-0.9-1.0-0.3-1.1
Social response proportion1.31.43.8-1.9-1.3-1.91.61.71.7-1.41.3-0.6-0.70.50.7-0.6-0.6-0.6-0.6-0.51.50.5
Social responses2.22.86.40.21.10.3-0.3-0.3-0.31.1-1.22.01.9-2.1-1.92.11.92.01.92.12.52.5
Social time1.21.62.51.41.61.1-1.2-1.4-1.41.3-1.41.21.3-1.2-1.41.11.51.31.41.20.01.2
Soleus weight0.51.43.8-0.8-1.9-0.80.61.00.9-1.21.2-1.3-1.41.31.2-1.2-1.3-1.2-1.3-1.0-0.8-1.2
Bone: stiffness0.30.51.1-0.3-0.6-0.20.20.30.5-0.50.6-0.8-0.80.90.8-0.9-0.7-0.8-0.8-0.8-0.7-1.0
Tibialis anterior weight2.79.222.8-0.4-3.7-0.8-0.90.60.5-2.52.2-4.1-3.53.83.4-3.4-3.4-3.4-3.5-3.1-4.8-3.7
Time to tail flick, vehicle, before self-admin0.20.21.20.61.10.6-0.3-0.6-0.50.5-0.50.50.5-0.4-0.40.30.40.50.40.3-0.00.3
Time to tail flick, vehicle, after self-admin1.41.57.1-0.8-2.7-0.90.40.91.0-1.21.2-1.4-1.41.31.2-1.5-1.2-1.0-1.2-0.9-0.7-1.0
Time to tail flick, test, before self-admin0.80.72.70.71.61.0-0.9-0.7-0.80.9-0.90.90.9-0.8-0.80.80.90.80.90.40.2-0.3
Time to tail flick, test, after self-admin1.51.610.1-1.00.3-0.31.41.00.90.1-0.11.41.0-1.4-1.11.31.21.21.20.83.21.5
Delta time to tail flick, vehicle, before/after SA1.61.63.8-1.5-2.0-1.51.01.31.4-1.41.3-1.2-1.31.11.2-1.3-1.2-1.1-1.1-1.30.2-0.9
Delta time to tail flick, test, before/after SA1.71.55.3-1.9-1.4-1.52.21.91.8-1.21.2-0.1-0.40.00.3-0.1-0.3-0.2-0.3-0.22.30.9
Tibia length2.87.815.43.33.92.9-3.0-3.4-3.23.0-3.12.52.8-2.5-2.62.62.62.52.62.4-0.52.3
Ambulatory time before self-admin0.20.21.20.40.20.3-0.3-0.4-0.50.3-0.0-0.3-0.20.40.3-0.3-0.2-0.3-0.3-0.2-1.1-0.7
Ambulatory time after self-admin0.80.92.90.0-1.00.1-0.80.1-0.1-0.50.5-1.2-1.11.11.0-0.8-0.9-1.0-1.0-1.1-1.7-1.5
Bone: tissue strength0.50.51.00.90.81.0-0.9-0.9-0.80.9-0.80.70.7-0.6-0.70.60.70.60.70.5-0.10.2
Total heroin consumption0.60.72.60.2-0.8-0.2-0.4-0.20.0-0.30.5-1.0-1.01.11.0-1.0-0.8-1.1-0.9-0.8-1.6-1.1
Bone: trabecular number1.32.03.40.71.60.9-0.2-0.7-0.61.3-1.31.81.7-1.7-1.71.41.71.71.71.51.61.4
Bone: trabecular spacing0.91.22.6-0.2-1.4-0.3-0.10.40.2-0.90.9-1.4-1.31.31.3-1.0-1.3-1.3-1.3-1.1-1.6-1.5
Bone: trabecular thickness0.60.71.80.81.31.1-0.7-0.8-0.71.1-0.81.00.9-0.7-0.80.50.90.80.80.50.20.0
Bone: trabecular tissue density0.40.61.5-0.0-0.7-0.2-0.2-0.00.1-0.60.5-0.9-0.91.00.9-1.0-0.9-0.9-0.9-0.9-1.2-0.9
Water consumed over 24 hours0.30.31.70.1-0.2-0.4-0.6-0.3-0.3-0.10.1-0.7-0.40.60.5-0.7-0.5-0.5-0.5-0.4-1.3-0.9
Number of responses in last shaping day0.60.62.11.20.71.1-1.5-1.2-1.20.7-0.80.30.5-0.4-0.40.50.40.40.40.5-1.00.0