Hub : Genes

Cgrrf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Cgrrf1 0.07 0.04 8.9e-03 -0 0.01 -0 -0 9.0e-01 1.3e-01 6.1e-01 5.4e-01
2 Brain gene expression Cgrrf1 0.08 0.04 4.1e-09 0.08 0.1 0.1 0.09 4.5e-08 1.7e-09 2.6e-09 4.8e-09
3 pVTA intron excision ratio chr15_22582670_22588012 0.1 0.08 3.5e-05 0.05 0.06 0.06 0.06 6.9e-05 1.1e-05 1.4e-05 7.3e-06
4 pVTA mRNA stability Cgrrf1 0.03 0.02 9.3e-04 0.03 0.03 0.02 0.02 1.1e-03 9.2e-04 4.5e-03 4.7e-03
5 NAcc intron excision ratio chr15_22582670_22588012 0.07 0.03 2.3e-15 0.1 0.1 0.1 0.1 8.7e-15 1.6e-15 1.9e-14 1.4e-14
6 Brain intron excision ratio chr15_22582670_22588012 0.04 0.02 5.3e-04 0.04 0.03 0.04 0.04 1.7e-04 4.4e-04 1.9e-04 1.7e-04
7 Liver gene expression Cgrrf1 0.02 0.02 9.2e-03 -0 0 -0 -0 7.5e-01 2.0e-01 9.6e-01 5.9e-01
8 Adipose gene expression Cgrrf1 0.04 0.02 3.6e-04 0.03 0.02 0.02 0.03 4.0e-04 1.3e-03 1.0e-03 3.4e-04
9 NAcc gene expression Cgrrf1 0.07 0.03 1.7e-09 0.08 0.06 0.06 0.07 9.0e-12 1.5e-09 7.5e-10 2.0e-11
10 NAcc isoform ratio NM_053899.2 0.04 0.02 1.9e-05 0.04 0.03 0.02 0.02 4.6e-06 5.8e-05 1.0e-03 1.9e-04
11 NAcc isoform ratio XM_039092952.1 0.04 0.03 1.3e-05 0.03 0.03 0.02 0.02 7.9e-06 8.4e-05 2.0e-04 2.9e-04
12 PL intron excision ratio chr15_22582670_22588012 0.03 0.01 1.0e-03 0.04 0.02 0.03 0.04 1.9e-05 1.2e-03 1.8e-04 9.9e-05
13 Brain mRNA stability Cgrrf1 0.11 0.05 1.2e-05 0.06 0.05 0.04 0.05 1.8e-06 1.8e-05 6.7e-05 8.1e-06
14 pVTA isoform ratio NM_053899.2 0.04 0.02 7.4e-04 0.04 0.04 0.03 0.04 2.5e-04 7.3e-04 1.7e-03 7.7e-04
15 Liver isoform ratio NM_053899.2 0.02 0.01 8.2e-03 0.02 0.01 0.01 0.01 1.1e-03 2.4e-02 6.9e-02 8.9e-03
16 NAcc mRNA stability Cgrrf1 0.03 0.01 6.6e-05 0.03 0.03 0.03 0.03 6.7e-06 1.2e-05 4.5e-05 1.0e-05
17 PL gene expression Cgrrf1 0.04 0.02 6.6e-04 0.02 0.03 0.03 0.03 5.8e-03 4.1e-04 3.5e-04 8.8e-04
18 Eye alternative TSS NM_053899.2 0.4 0.16 6.6e-03 -0.01 -0 -0.01 0.02 4.7e-01 3.4e-01 5.4e-01 1.8e-01
19 BLA intron excision ratio chr15_22582670_22588012 0.11 0.06 1.9e-03 0.03 0.05 0 0.02 1.7e-02 9.2e-04 1.8e-01 3.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.91.63.21.61.6-1.8-1.4-1.3-0.7-1.21.5-1.21.3-1.31.30.81.20.81.5-1.60.4-0.5
Area under the delay curve0.20.32.9-0.40.10.3-0.10.2-0.4-0.31.40.2-0.20.2-0.3-0.2-0.2-0.6-0.3-0.2-1.7-0.6
BMI with tail0.41.45.0-2.2-2.01.41.41.40.81.0-1.80.8-0.80.8-1.0-0.7-1.0-0.8-1.00.4-0.40.2
BMI without tail0.31.45.3-2.3-1.41.31.41.40.91.3-0.00.9-0.90.9-1.1-0.2-1.2-0.5-0.70.8-2.3-0.2
Body weight2.08.913.0-3.5-3.63.23.43.43.33.0-2.83.0-3.03.0-3.1-2.8-3.1-2.9-3.12.3-1.12.2
Weight adjusted by age0.20.72.3-1.4-1.21.51.10.80.61.1-0.30.6-0.70.7-0.5-0.4-0.4-0.4-0.51.40.30.2
Bone surface0.10.20.90.70.4-0.8-0.2-0.20.50.00.9-0.30.3-0.30.4-0.40.1-0.40.8-0.60.40.5
Bone volume0.20.51.50.80.6-1.2-0.6-0.5-0.0-0.40.7-0.60.7-0.70.80.10.50.10.9-1.20.50.1
Breakpoint value in progressive ratio session0.40.77.3-1.4-0.20.40.60.70.50.80.8-0.20.1-0.10.2-0.30.3-0.40.40.6-2.7-0.7
Number of licking bursts0.10.41.30.30.2-0.9-0.6-0.5-0.8-0.7-0.5-0.70.6-0.60.50.60.50.60.3-1.20.6-0.4
Context. condit. distance diff. score0.30.41.30.20.5-0.3-0.7-0.6-0.7-0.9-0.2-0.60.5-0.50.40.60.50.60.7-0.5-0.4-1.1
Locomotion velocity, session 10.60.72.0-0.7-0.80.60.90.91.01.0-0.30.8-0.70.7-0.7-0.9-0.7-0.8-1.40.7-0.31.0
Locomotion distance, session 10.50.63.30.4-0.30.40.40.41.20.4-0.50.8-0.70.7-0.8-0.8-0.8-0.7-1.80.50.81.3
Locomotion velocity, session 20.20.20.90.20.5-0.3-0.4-0.4-0.5-0.30.9-0.40.4-0.40.50.40.70.5-0.50.1-0.1-0.5
Locomotion distance, session 20.60.94.30.0-0.50.50.70.71.00.80.30.9-0.90.9-0.9-1.0-1.0-1.0-2.10.80.51.4
Locomotion velocity, session 30.10.10.40.2-0.00.10.20.20.60.30.20.4-0.20.2-0.2-0.4-0.2-0.5-0.30.40.00.4
Locomotion distance, session 31.21.42.11.21.3-1.4-1.3-1.3-1.3-1.31.1-1.11.2-1.21.31.11.31.10.9-1.3-0.4-1.0
Stereotopy head waving bouts, day 30.70.81.6-0.4-0.80.70.90.91.30.8-0.90.9-0.90.9-1.0-1.1-1.2-1.1-0.80.60.61.1
Stereotopy head waving duration, day 31.11.32.6-1.1-1.11.21.31.21.51.4-0.71.0-1.01.0-1.1-1.2-1.3-1.1-1.01.60.11.0
Locomotion velocity, session 70.30.31.6-0.8-0.20.60.40.4-0.10.21.00.4-0.40.4-0.3-0.1-0.2-0.2-0.70.7-1.3-0.5
Locomotion distance, session 70.20.21.8-0.5-0.10.30.30.40.40.31.30.4-0.20.20.0-0.50.1-0.5-0.10.6-1.0-0.1
Stereotopy head waving bouts, day 70.40.51.41.20.8-0.7-0.7-0.8-1.0-0.60.3-0.70.6-0.60.40.50.40.50.6-0.51.0-0.1
Stereotopy head waving duration, day 70.40.51.30.70.7-0.5-0.6-0.8-1.1-0.60.2-0.80.8-0.80.50.80.50.80.5-0.20.8-0.7
Locomotion velocity, session 80.20.20.7-0.2-0.10.90.30.30.50.30.20.5-0.50.5-0.4-0.5-0.2-0.5-0.10.8-0.50.0
Locomotion distance, session 80.10.10.80.40.20.3-0.1-0.10.0-0.10.40.4-0.50.5-0.5-0.2-0.4-0.2-0.90.5-0.00.2
Degree of sensitization distance2.42.63.8-1.4-1.51.91.71.71.91.7-0.31.8-1.81.8-1.7-1.9-1.6-1.8-1.21.8-0.11.5
Degree of sensitization stereotypy0.91.02.81.10.9-0.9-0.9-1.1-1.7-0.80.2-1.21.1-1.10.91.00.91.00.7-0.51.1-0.6
Conditioned locomotion0.50.62.00.40.6-1.0-0.8-0.7-0.6-0.90.4-0.70.6-0.60.80.80.90.80.1-1.4-0.5-0.7
Cocaine response after cond. corrected0.10.20.7-0.8-0.70.40.50.50.20.3-0.80.1-0.10.1-0.0-0.4-0.1-0.4-0.50.50.10.0
Cocaine response after cond. not corrected0.00.00.2-0.2-0.10.10.20.20.30.2-0.20.00.0-0.00.2-0.40.0-0.40.10.50.10.1
Cocaine response before conditioning0.40.53.01.51.4-0.5-0.7-0.60.1-0.21.7-0.10.2-0.20.2-0.10.2-0.01.10.10.20.4
Saline control response1.62.26.62.62.5-1.8-1.8-1.6-1.0-1.42.3-1.01.1-1.11.10.81.20.81.5-1.3-0.3-0.5
Bone: connectivity density0.20.42.41.00.9-0.7-0.6-0.50.2-0.41.5-0.30.3-0.30.4-0.10.2-0.10.9-0.50.30.2
Bone: cortical apparent density4.26.710.03.23.1-2.9-3.0-2.9-2.3-2.91.5-2.62.7-2.72.72.33.02.32.6-2.31.6-1.8
Bone: cortical area4.06.48.72.22.1-2.9-2.7-2.8-2.8-2.60.6-2.82.8-2.82.82.82.72.81.7-2.82.3-2.1
Bone: cortical porosity0.00.00.30.30.1-0.1-0.1-0.20.1-0.2-0.10.2-0.20.2-0.30.1-0.20.1-0.20.20.50.0
Bone: cortical porosity0.10.10.20.30.0-0.10.10.00.30.0-0.00.4-0.40.4-0.5-0.2-0.4-0.2-0.40.30.50.3
Bone: cortical thickness7.412.415.63.53.7-3.9-4.0-4.0-3.8-3.92.0-3.73.8-3.83.83.73.73.72.7-3.31.7-3.1
Bone: cortical thickness4.45.48.11.22.0-2.4-2.2-2.2-2.9-2.11.6-2.62.7-2.72.52.52.72.62.8-2.2-0.3-2.6
Bone: cortical tissue density3.75.89.13.02.9-2.7-2.8-2.7-2.2-2.71.5-2.42.5-2.52.52.12.82.12.5-2.11.4-1.7
Condit. Reinf. active minus inactive responses0.40.41.30.90.0-0.3-0.10.10.6-0.3-1.00.5-0.50.5-0.6-0.7-0.6-0.7-0.2-0.61.21.1
Condit. Reinf. active-inactive response ratio0.40.42.50.4-0.1-0.5-0.4-0.20.1-0.7-1.6-0.10.1-0.10.1-0.10.0-0.10.7-1.11.40.1
Condit. Reinf. active responses0.60.83.31.20.1-0.3-0.00.30.8-0.0-0.50.9-1.01.0-1.1-1.0-1.0-1.0-1.3-0.40.91.8
Condit. Reinf. inactive responses1.11.45.80.7-0.00.20.50.71.00.70.71.3-1.41.4-1.5-1.2-1.3-1.2-2.40.6-0.62.0
Incentive salience index mean0.50.63.21.00.1-0.00.20.30.80.3-0.20.8-0.80.8-0.9-0.9-0.9-0.9-0.50.01.01.8
Condit. Reinf. lever presses0.81.24.50.60.00.50.80.71.01.31.21.0-1.11.1-1.2-1.2-1.2-1.2-1.01.20.12.1
Condit. Reinf. active minus inactive responses0.30.41.91.40.5-0.6-0.4-0.30.3-0.40.40.4-0.50.5-0.6-0.2-0.6-0.3-0.6-0.50.91.1
Condit. Reinf. active-inactive response ratio0.10.21.30.6-0.1-0.2-0.1-0.00.4-0.2-0.30.3-0.30.3-0.3-0.2-0.3-0.2-0.1-0.51.10.8
Condit. Reinf. active responses0.20.32.01.40.9-0.9-0.6-0.50.1-0.50.70.1-0.00.0-0.2-0.1-0.2-0.20.2-0.70.30.6
Condit. Reinf. inactive responses0.20.31.71.01.0-0.6-0.6-0.5-0.3-0.41.3-0.00.2-0.20.10.10.10.10.6-0.3-0.7-0.1
Condit. Reinf. lever presses0.10.10.40.40.3-0.2-0.1-0.1-0.10.00.60.2-0.10.1-0.20.1-0.20.0-0.60.1-0.20.3
Condit. Reinf. lever reinforcers received0.20.32.01.40.9-0.9-0.6-0.50.0-0.50.80.1-0.00.0-0.1-0.0-0.2-0.10.0-0.50.10.6
Conditioned reinforcement - actives0.10.41.5-1.0-0.80.81.00.80.51.2-0.20.3-0.40.4-0.4-1.0-0.4-0.2-0.20.7-0.50.4
Conditioned reinforcement - inactives0.41.11.9-1.4-1.31.41.21.31.01.2-0.60.9-0.90.9-0.8-1.3-0.9-1.2-1.00.7-0.50.7
Conditioned locomotion0.20.31.1-0.60.0-0.40.30.2-0.40.80.7-0.70.8-0.80.4-0.40.40.20.20.4-1.0-0.2
Patch foraging indifference point 0 sec0.20.52.71.11.2-0.8-0.7-0.7-0.6-0.41.6-0.60.5-0.50.50.50.60.20.7-0.6-0.5-0.1
Patch foraging indifference point AUC0.30.81.70.10.4-0.8-0.6-0.6-1.0-0.7-0.6-1.31.3-1.31.20.61.20.50.9-0.80.5-1.0
Delay disc. indifference point, 0s delay0.50.51.60.2-0.50.60.10.40.4-0.3-1.20.8-0.70.7-1.0-0.6-1.1-1.2-1.1-0.40.30.7
Delay disc. indifference point, 16s delay0.20.31.8-0.10.4-0.4-0.4-0.1-0.3-0.61.3-0.30.1-0.10.20.00.4-0.10.4-0.9-1.1-0.7
Delay disc. indifference point, 2s delay0.10.11.1-0.5-0.30.30.20.4-0.10.0-0.10.2-0.10.1-0.2-0.5-0.4-0.7-0.3-0.2-1.1-0.1
Delay disc. indifference point, 24s delay1.01.65.80.31.3-0.8-1.1-0.9-1.2-1.12.4-1.01.2-1.21.11.31.30.71.5-0.8-1.5-1.7
Delay disc. indifference point, 4s delay0.70.72.5-0.3-0.51.00.50.60.30.30.40.9-1.11.1-1.3-0.9-1.4-1.1-1.60.6-0.40.5
Delay disc. indifference point, 8s delay0.30.43.6-0.30.10.30.00.3-0.2-0.21.40.5-0.50.5-0.6-0.3-0.4-0.5-0.5-0.2-1.9-0.3
Indifference point function ln k0.10.31.31.10.8-0.1-0.3-0.50.3-0.11.10.4-0.50.5-0.10.2-0.10.30.10.00.40.6
Indifference point function log k0.10.31.31.10.8-0.1-0.3-0.50.3-0.11.10.4-0.50.5-0.10.2-0.10.30.10.00.40.6
Patch foraging total patch changes 0 sec0.20.62.21.11.2-0.8-0.8-0.8-0.7-0.61.5-0.70.6-0.60.70.60.70.30.8-0.9-0.5-0.3
Patch foraging total patch changes 12 sec0.71.01.80.21.0-0.6-0.7-0.7-1.0-0.51.3-1.21.2-1.21.20.91.20.71.1-0.7-1.2-1.2
Patch foraging total patch changes 18 sec0.81.83.40.91.3-1.8-1.3-1.1-1.5-1.10.8-1.71.7-1.71.70.91.60.91.4-1.6-0.6-1.1
Patch foraging total patch changes 24 sec0.20.61.30.70.6-1.1-0.7-0.7-0.9-0.6-0.1-0.90.9-0.90.90.41.00.40.7-1.00.4-0.3
Patch foraging total patch changes 6 sec0.71.22.50.81.3-0.8-1.1-1.0-1.2-0.81.6-1.31.2-1.21.20.91.40.81.1-0.9-0.6-1.0
Patch foraging time to switch 0 sec0.31.02.0-0.9-1.01.30.91.00.70.7-0.41.2-1.11.1-1.4-0.8-1.3-1.0-1.40.8-0.80.6
Patch foraging water rate 0 sec0.83.04.91.61.7-2.2-1.9-1.9-2.1-1.90.6-1.71.7-1.72.12.01.61.91.5-1.90.5-1.6
Patch foraging water rate 12 sec0.31.12.61.21.1-1.2-1.0-1.3-1.5-0.80.3-1.21.1-1.11.01.30.91.60.4-0.30.7-0.9
Patch foraging water rate 18 sec0.81.93.81.71.2-1.3-1.6-1.7-1.6-1.70.2-0.90.8-0.80.91.90.61.81.3-1.71.5-1.0
Patch foraging water rate 24 sec1.52.13.91.71.3-1.4-1.6-1.8-1.3-1.60.4-1.21.3-1.31.41.81.12.01.4-1.51.8-0.9
Patch foraging water rate 6 sec0.40.61.80.70.7-1.2-0.9-0.8-0.8-1.1-0.3-0.40.4-0.40.91.10.60.70.5-1.3-0.2-0.8
Seeking ratio, delayed vs. immediate footshock0.40.61.90.7-0.20.40.20.20.40.2-0.01.0-1.21.2-1.0-0.2-1.0-0.1-0.9-0.31.01.4
Distance traveled before self-admin0.51.12.61.20.6-1.4-1.1-1.1-1.0-1.3-0.7-0.81.0-1.00.90.90.91.00.9-1.51.6-0.4
Distance traveled after self-admin1.01.83.31.11.1-1.2-1.4-1.4-1.8-1.50.5-1.51.5-1.51.31.71.41.31.2-1.20.9-1.3
Extensor digitorum longus weight0.20.76.3-0.20.6-0.9-0.4-0.2-0.4-0.21.2-0.70.7-0.70.50.30.40.30.6-0.7-2.5-0.8
Bone: elastic displacement0.81.05.42.31.8-0.7-1.3-1.3-1.0-1.01.7-0.20.1-0.10.10.80.20.80.6-0.20.70.1
Bone: elastic work0.91.26.52.61.6-1.0-1.4-1.5-0.8-1.21.0-0.30.2-0.20.20.70.10.70.7-0.71.90.4
Bone: endosteal estimation1.23.06.2-2.0-2.51.62.11.91.82.1-2.11.6-1.71.7-1.7-1.4-1.7-1.5-1.01.00.81.8
Bone: endosteal perimeter1.43.36.1-1.7-2.51.62.11.81.82.1-1.91.7-1.91.9-1.9-1.4-1.8-1.5-2.21.21.12.1
Epididymis fat weight1.57.410.7-2.9-3.32.93.13.12.82.8-2.42.9-2.82.8-2.8-2.6-2.7-2.8-2.72.2-0.42.3
Delta time in closed arm before/after self-admin0.40.43.3-0.3-0.80.50.30.10.30.1-1.70.10.1-0.1-0.2-0.3-0.3-0.1-0.4-0.01.80.3
Delta time in open arm before/after self-admin0.20.30.70.30.5-0.8-0.5-0.4-0.2-0.5-0.0-0.70.7-0.70.60.40.60.10.7-0.4-0.2-0.5
Diff in mean of infusions in LGA sessions1.42.55.3-1.8-1.52.31.61.71.61.4-0.31.8-1.91.9-1.5-1.4-1.4-1.5-1.71.4-1.20.9
Delay discount exponential model param0.30.42.80.5-0.0-0.4-0.1-0.30.30.1-1.4-0.30.4-0.40.50.30.30.70.40.01.70.4
Extinction: sum of active levers before priming0.20.31.00.20.5-0.2-0.1-0.10.40.30.3-0.70.7-0.70.7-0.70.90.01.00.4-0.10.2
Active lever presses in extinction session 60.20.20.9-0.9-0.50.80.60.3-0.00.60.10.2-0.30.3-0.10.40.0-0.1-0.00.8-0.6-0.4
Bone: final force0.50.82.00.70.5-1.4-0.8-0.9-1.1-0.80.4-0.90.9-0.90.90.90.60.80.5-1.31.1-0.4
Bone: final moment0.91.43.21.20.9-1.8-1.2-1.3-1.3-1.10.5-1.21.2-1.21.31.11.01.00.8-1.61.4-0.5
Food consumed during 24 hour testing period0.00.10.70.1-0.10.20.10.10.30.10.10.2-0.20.2-0.2-0.3-0.3-0.2-0.8-0.00.10.4
Glucose0.50.84.1-0.6-1.30.80.60.60.60.0-2.00.8-0.80.8-0.9-0.5-1.1-0.6-0.8-0.21.60.6
Heart weight0.71.12.9-1.7-1.31.21.21.20.91.0-0.21.0-1.01.0-1.0-0.7-1.3-0.7-1.40.9-1.10.2
Delay discount hyperbolic model param0.40.53.30.80.2-0.7-0.4-0.60.0-0.2-1.2-0.60.6-0.60.70.60.60.90.6-0.31.80.2
Intermittent access intake day 1-15 change0.10.51.3-0.4-0.70.70.70.60.60.5-0.70.9-0.90.9-0.9-0.8-0.9-0.6-1.10.40.30.7
Intermittent access intake escalation0.21.01.7-0.7-1.01.01.00.91.01.0-0.81.2-1.11.1-1.1-1.1-1.1-0.8-1.31.00.31.0
Intermittent access intake escalation 20.30.41.0-0.0-0.40.50.60.50.80.70.10.9-0.80.8-0.7-0.6-0.9-0.5-1.00.70.10.9
Intermitt. access day 1 inactive lever presses0.10.73.6-0.10.6-1.0-0.5-0.2-1.0-0.30.6-1.11.0-1.00.90.31.00.40.4-0.8-1.9-0.7
Intermitt. access day 15 inactive lever presses0.10.40.8-0.2-0.30.30.60.60.40.80.80.6-0.70.7-0.5-0.7-0.6-0.3-0.90.8-0.60.8
Intermitt. access escalation Index1.03.14.61.22.0-2.1-1.6-1.7-1.9-1.11.6-2.12.1-2.12.01.91.92.01.9-0.7-0.4-1.7
Intermittent access day 1 total infusions0.41.23.8-1.9-1.21.01.51.51.11.80.10.6-0.50.5-0.5-1.2-0.4-1.0-0.10.9-1.80.5
Intermittent access day 15 total infusions0.82.05.6-2.4-1.61.51.81.81.41.9-0.31.1-1.01.0-1.1-1.3-0.9-1.1-0.81.5-1.80.5
Intermittent access terminal intake (last 3 days)0.71.33.7-1.9-1.11.11.41.41.11.70.50.9-0.80.8-0.6-1.3-0.6-0.8-0.40.9-1.90.5
Intermittent access total infusions1.01.24.7-2.0-1.11.11.41.40.91.70.30.6-0.50.5-0.4-1.1-0.3-0.70.10.9-2.20.2
Intermittent access day 1 locomotion0.91.65.3-2.1-1.31.21.81.70.92.30.10.7-0.50.5-0.7-1.3-0.5-0.9-0.21.6-1.70.7
Intermittent access day 15 total locomotion1.03.98.7-2.9-2.72.22.62.51.62.7-1.61.7-1.51.5-1.7-2.0-1.7-1.7-1.62.0-0.91.3
Intermittent access total locomotion1.11.44.5-2.1-1.31.21.61.60.61.90.00.6-0.50.5-0.8-1.3-0.7-0.6-0.41.1-2.10.5
Intermittent access standard deviation0.31.66.1-1.7-1.11.11.31.41.11.30.91.2-1.21.2-1.1-1.2-1.2-1.2-1.20.9-2.50.3
Left kidney weight0.22.03.8-1.0-1.21.71.41.31.51.2-1.11.6-1.51.5-1.9-1.3-1.8-1.6-1.41.6-0.21.1
Right kidney weight0.53.25.50.0-1.21.71.31.22.11.1-1.72.1-2.12.1-2.3-1.7-2.1-2.0-2.01.81.52.2
Cocaine induced anxiety0.20.63.9-0.50.6-0.3-0.5-0.2-0.2-0.51.4-0.70.7-0.70.60.10.70.80.5-0.3-2.0-1.2
Post-drug Anxiety0.10.10.40.10.40.0-0.4-0.20.4-0.6-0.0-0.30.2-0.20.2-0.10.40.1-0.1-0.2-0.6-0.5
Baseline Anxiety0.30.54.11.20.3-0.1-0.6-0.7-0.1-0.9-1.50.0-0.10.10.20.60.1-0.2-0.3-0.32.00.1
Tail length0.42.23.7-1.0-0.71.41.51.41.91.80.71.7-1.61.6-1.7-1.2-1.8-1.6-1.21.8-1.81.2
Length with tail1.46.110.6-1.8-2.22.32.62.63.22.6-1.52.7-2.72.7-2.6-2.7-2.6-2.9-2.62.3-0.72.6
Length without tail0.73.85.3-1.6-2.11.72.12.02.12.0-2.22.0-2.02.0-1.8-2.2-1.7-2.3-2.31.70.12.0
Times rat made contact with spout0.40.40.90.00.3-0.8-0.4-0.4-0.5-0.10.5-0.90.9-0.91.00.51.00.60.5-0.8-0.1-0.4
Lifetime Intake1.82.25.1-2.3-1.61.61.91.91.62.2-0.21.2-1.21.2-1.0-1.8-0.9-1.3-0.51.3-1.80.9
Liver weight, left0.10.21.30.60.4-0.2-0.2-0.5-1.00.11.1-0.10.1-0.10.10.9-0.10.60.00.10.5-0.0
Liver weight, right0.20.42.7-1.0-1.10.60.80.60.70.6-1.60.2-0.00.0-0.3-0.1-0.1-0.20.4-0.00.90.2
Locomotor activity0.50.83.70.41.1-1.0-0.6-0.5-0.3-0.21.9-0.90.8-0.80.80.10.60.30.5-0.3-1.9-0.6
Locomotor testing distance0.30.72.61.31.2-1.6-0.9-0.8-0.2-0.51.2-1.11.0-1.00.80.00.50.10.4-0.6-0.10.0
Locomotor testing rearing0.41.44.11.81.8-1.7-1.3-1.4-0.7-0.92.0-1.31.3-1.31.20.50.90.50.9-0.30.2-0.4
Locomotion in novel chamber0.10.20.70.40.6-0.5-0.6-0.3-0.2-0.70.9-0.20.2-0.20.00.4-0.10.4-0.3-0.5-0.7-0.3
Locomotion in novel chamber post-restriction0.31.02.70.41.1-1.0-0.7-0.8-0.5-0.31.2-1.11.4-1.41.40.61.31.11.6-0.3-0.4-1.0
Fecal boli incidents, locomotor time 10.20.51.60.70.5-1.0-0.6-0.7-0.5-0.5-0.2-0.80.8-0.80.80.40.90.71.3-0.60.9-0.3
Change in fecal boli incidents, locomotor task0.91.03.10.61.1-0.5-1.0-0.9-1.3-1.11.8-0.80.7-0.71.00.91.10.80.5-1.3-0.6-1.3
Time >=10cm from walls, locomotor time 10.60.72.30.20.7-0.5-0.6-0.6-0.4-0.30.9-0.71.0-1.01.00.81.11.01.5-0.6-0.7-1.0
Bouts of movement, locomotor time 10.20.30.70.80.4-0.6-0.7-0.6-0.4-0.8-0.4-0.20.6-0.60.30.80.30.40.4-0.80.8-0.2
Total resting periods, locomotor time 10.50.61.41.10.8-1.0-1.0-0.9-0.5-1.10.2-0.40.8-0.80.50.90.50.60.4-1.20.5-0.3
Rest time, locomotor task time 10.50.92.00.81.2-0.9-1.0-0.9-0.6-0.81.4-1.11.2-1.21.10.60.80.60.8-1.0-0.6-0.8
Distance moved, locomotor task time 10.20.61.6-0.6-1.00.40.80.80.60.7-1.30.9-0.70.7-0.9-0.7-0.7-0.8-0.0-0.00.51.0
Vertical activity count, locomotor time 10.11.01.8-1.2-1.11.01.11.10.61.0-0.41.1-1.31.3-1.3-0.6-1.1-0.7-0.70.5-1.10.6
Time >=10cm from walls, locomotor time 20.10.30.70.10.1-0.6-0.3-0.3-0.3-0.1-0.4-0.40.8-0.80.70.50.90.50.6-0.60.6-0.2
Bouts of movement, locomotor time 20.30.82.00.2-0.40.50.60.71.40.5-0.01.3-1.01.0-1.1-1.1-1.3-1.1-1.20.30.11.3
Total resting periods, locomotor time 20.20.61.50.3-0.30.50.40.51.20.40.01.2-0.90.9-1.0-0.9-1.2-0.9-1.00.30.31.2
Rest time, locomotor task time 20.30.50.80.20.7-0.5-0.6-0.5-0.9-0.50.9-0.80.8-0.80.70.60.60.70.7-0.3-0.7-0.8
Distance moved, locomotor task time 20.20.21.50.30.1-0.8-0.5-0.4-0.5-0.5-0.4-0.30.3-0.30.20.40.30.20.6-1.20.2-0.3
Vertical activity count, locomotor time 20.10.10.8-0.4-0.2-0.3-0.2-0.0-0.3-0.4-0.1-0.1-0.10.1-0.10.30.10.10.2-0.9-0.7-0.5
Light reinforcement 10.10.30.8-0.4-0.40.50.60.60.70.7-0.20.6-0.50.5-0.4-0.5-0.5-0.90.10.4-0.50.5
Light reinforcement 20.40.81.4-0.8-1.11.21.11.01.21.0-0.90.9-1.01.0-1.0-0.8-0.8-1.0-0.40.40.00.9
Bone: marrow area1.22.95.9-1.9-2.41.62.01.91.82.0-2.01.6-1.61.6-1.7-1.4-1.7-1.5-0.91.00.61.7
Bone: maximum diameter0.51.06.3-1.7-1.90.41.00.80.30.8-2.50.10.0-0.0-0.1-0.0-0.1-0.0-1.1-0.31.40.2
Bone: maximum force0.40.82.20.90.5-1.3-0.9-0.9-0.9-0.90.0-0.90.9-0.90.80.80.60.70.7-1.51.3-0.3
Bone: maximum moment0.71.42.91.40.9-1.7-1.3-1.3-1.0-1.20.1-1.11.2-1.21.20.90.90.81.0-1.71.7-0.4
Mean time between licks in bursts0.10.41.20.90.8-0.8-0.8-0.6-0.2-0.81.0-0.30.4-0.40.50.20.50.20.7-1.10.6-0.0
Mean num. licks in bursts0.00.10.5-0.10.10.40.20.20.50.40.70.10.0-0.00.1-0.20.2-0.20.00.5-0.40.1
Cd content in liver0.50.51.10.20.6-0.6-0.7-0.6-0.8-0.70.8-0.50.6-0.60.70.80.60.70.8-0.7-1.0-1.1
Co content in liver2.83.24.51.71.8-2.0-1.9-2.1-2.0-1.80.8-2.02.0-2.01.92.01.82.01.7-1.40.5-1.8
Cu content in liver0.60.71.4-0.3-0.20.70.70.71.10.91.20.7-0.80.8-0.8-0.8-0.8-0.9-0.91.2-1.20.7
Fe content in liver0.40.51.91.21.4-0.7-0.9-0.7-0.3-0.71.2-0.50.5-0.50.60.20.60.20.7-0.1-0.6-0.3
K content in liver0.40.41.41.20.9-0.7-0.8-0.8-0.3-0.70.6-0.70.5-0.50.40.50.40.50.5-0.50.6-0.1
Mg content in liver0.80.84.10.71.1-0.9-0.6-0.8-0.9-0.32.0-1.10.9-0.90.71.00.70.90.9-0.2-0.7-0.8
Mn content in liver0.60.71.4-0.6-0.90.80.90.91.20.7-0.80.8-0.90.9-1.0-1.1-1.0-1.1-0.60.30.10.8
Na content in liver0.40.51.60.4-0.20.70.30.20.20.3-1.00.5-0.80.8-0.8-0.5-0.7-0.4-0.81.21.30.9
Rb content in liver0.40.53.50.70.8-0.5-0.2-0.00.40.11.90.3-0.20.2-0.2-0.4-0.4-0.5-0.0-0.2-1.60.4
Se content in liver0.10.10.50.50.30.2-0.00.10.6-0.10.40.1-0.20.2-0.1-0.6-0.1-0.70.00.4-0.10.3
Sr content in liver1.00.92.6-1.6-1.51.11.31.10.11.3-1.10.5-0.90.9-0.9-0.4-0.9-0.4-0.80.6-0.20.4
Zn content in liver1.01.13.40.10.9-1.3-0.7-0.5-0.6-0.41.8-1.31.3-1.31.10.81.10.71.0-0.7-1.6-1.1
Bone: minimum diameter0.51.02.81.10.7-1.5-1.0-1.1-0.7-0.9-0.2-1.01.0-1.01.00.90.90.90.7-1.21.7-0.3
Time in familiar zone, hab. session 10.70.82.4-0.5-0.20.80.80.70.91.11.60.7-0.80.8-0.9-1.0-0.9-1.0-0.51.4-1.00.7
Time in novel zone, hab. session 10.50.61.80.20.1-0.8-0.6-0.5-0.7-0.7-1.3-0.60.8-0.80.90.70.90.70.8-1.30.8-0.5
Total zone transitions, hab. session 10.20.21.50.80.4-0.3-0.4-0.5-0.4-0.30.4-0.30.2-0.20.20.40.30.50.1-0.31.20.2
Total locomotion distance, hab. session 10.10.21.10.60.6-0.5-0.4-0.5-0.4-0.31.1-0.40.4-0.40.40.30.40.3-0.2-0.40.0-0.1
Locomotion velocity, hab. session 10.20.31.70.90.8-0.5-0.5-0.6-0.6-0.31.3-0.40.4-0.40.40.30.40.4-0.3-0.20.3-0.1
Time in familiar zone, hab. session 20.60.72.81.21.1-1.2-1.0-0.8-0.7-0.91.7-0.60.6-0.60.60.40.60.4-0.2-0.80.3-0.1
Time in novel zone, hab. session 20.50.53.5-1.2-1.00.90.80.60.50.6-1.90.3-0.30.3-0.2-0.1-0.3-0.10.40.6-0.1-0.2
Total zone transitions, hab. session 21.11.43.21.31.4-1.4-1.1-1.2-1.0-0.61.8-1.41.4-1.41.41.11.41.10.4-0.50.2-0.6
Total locomotion distance, hab. session 21.11.53.10.91.3-1.4-1.1-1.2-1.4-0.71.8-1.51.5-1.51.41.21.21.30.3-0.7-0.7-1.0
Locomotion velocity, hab. session 21.01.33.40.81.3-1.3-1.0-1.1-1.3-0.51.8-1.41.4-1.41.41.11.31.20.3-0.6-0.7-0.9
Novel to familiar place preference ratio1.41.93.9-2.0-1.81.81.61.61.41.3-1.51.3-1.21.2-1.1-1.4-1.1-1.4-0.91.2-0.70.5
Novelty place preference1.41.83.7-1.9-1.81.81.61.61.31.4-1.41.3-1.11.1-1.1-1.4-1.1-1.4-1.01.3-0.60.5
Time in novel zone, NPP test1.11.32.6-1.6-1.51.51.41.41.21.2-1.31.1-1.01.0-0.9-1.2-1.0-1.2-0.81.0-0.50.5
Total zone transitions, NPP test0.20.21.50.50.6-0.5-0.3-0.5-0.10.01.2-0.60.5-0.50.60.20.70.30.1-0.20.1-0.1
Total locomotion distance, NPP test0.10.10.3-0.00.2-0.20.0-0.1-0.10.30.5-0.50.5-0.50.50.10.40.2-0.30.0-0.2-0.1
Locomotion velocity, NPP test0.10.20.6-0.4-0.10.30.40.30.20.70.7-0.10.1-0.10.2-0.20.0-0.1-0.70.7-0.40.1
Intraocular pressure0.20.32.2-1.1-0.5-0.00.30.60.6-0.0-0.60.00.1-0.10.1-0.60.1-0.5-0.3-0.2-1.5-0.5
Delta distance traveled before/after self-admin0.20.21.1-0.60.10.2-0.1-0.0-0.5-0.10.8-0.60.4-0.40.30.60.30.40.10.2-1.1-0.9
Delta ambulatory time before/after self-admin0.20.31.7-0.8-0.10.50.10.2-0.50.01.0-0.1-0.10.1-0.10.7-0.10.2-0.40.3-1.3-0.7
Parametrial fat weight7.617.827.3-4.2-4.64.74.64.64.24.3-2.54.6-4.54.5-4.6-3.7-4.6-4.3-5.24.0-1.53.5
Pavlov. Cond. lever latency0.30.41.0-1.0-0.90.80.50.60.50.1-0.90.8-0.70.7-0.6-0.5-0.6-0.6-0.30.3-0.4-0.3
Pavlov. Cond. magazine entry latency0.20.20.80.70.5-0.4-0.4-0.4-0.5-0.10.5-0.60.5-0.50.50.40.50.4-0.3-0.50.90.3
Pavlov. Cond. change in total contacts1.01.03.60.91.3-1.1-0.7-0.9-1.00.01.9-1.31.3-1.31.21.01.11.00.80.0-0.2-0.3
Pavlov. Cond. index score0.81.01.91.21.2-1.1-0.9-1.0-1.0-0.31.1-1.41.3-1.31.21.01.21.00.6-0.50.6-0.1
Pavlov. Cond. latency score0.40.51.10.90.9-0.7-0.5-0.6-0.50.11.0-0.90.8-0.80.70.60.80.70.3-0.20.50.3
Pavlov. Cond. lever contacts0.60.71.50.81.1-1.0-0.6-0.7-0.9-0.11.2-1.21.1-1.11.00.91.00.90.7-0.4-0.0-0.2
Pavlov. Cond. magazine entry number0.40.51.0-0.9-0.90.70.60.70.70.3-0.81.0-0.90.9-0.8-0.7-0.8-0.7-0.10.3-0.60.0
Pavlov. Cond. intertrial magazine entries1.01.22.7-0.2-0.60.50.71.11.60.4-0.51.4-1.41.4-1.5-1.7-1.4-1.6-0.80.4-0.51.4
Pavlov. Cond. lever-magazine prob. diff.1.11.42.61.21.3-1.1-1.0-1.2-1.4-0.61.1-1.61.5-1.51.31.31.31.30.7-0.70.8-0.4
Pavlov. Cond. response bias0.91.12.31.01.2-1.1-1.0-1.0-1.2-0.60.9-1.51.3-1.31.31.11.21.20.7-0.80.3-0.5
Pavlov. Cond. lever latency0.30.43.7-0.9-0.90.60.20.30.2-0.3-1.90.0-0.30.3-0.20.1-0.10.10.3-0.60.7-0.4
Pavlov. Cond. magazine entry latency0.10.20.80.1-0.1-0.30.30.40.70.5-0.00.3-0.10.1-0.1-0.60.0-0.70.30.0-0.00.9
Pavlov. Cond. change in total contacts0.10.20.90.30.6-0.3-0.2-0.2-0.40.00.9-0.20.3-0.30.30.30.50.20.40.2-0.9-0.2
Pavlov. Cond. index score0.20.31.20.60.7-0.8-0.3-0.2-0.20.11.1-0.30.6-0.60.60.10.60.10.3-0.1-0.70.1
Pavlov. Cond. latency score0.20.30.90.70.7-0.9-0.3-0.3-0.20.10.9-0.40.6-0.60.70.10.70.10.3-0.1-0.40.2
Pavlov. Cond. lever contacts0.30.54.90.81.0-0.6-0.2-0.3-0.30.32.2-0.10.4-0.40.3-0.10.2-0.1-0.20.6-1.10.2
Pavlov. Cond. magazine entry number0.10.10.5-0.4-0.30.70.10.1-0.1-0.3-0.30.3-0.50.5-0.50.1-0.70.2-0.4-0.0-0.1-0.5
Pavlov. Cond. intertrial magazine entries0.10.21.30.80.6-0.2-0.6-0.5-0.6-0.61.10.0-0.10.1-0.30.4-0.40.5-0.2-0.4-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.80.50.5-0.6-0.1-0.1-0.00.20.9-0.20.4-0.40.40.00.5-0.10.20.0-0.50.3
Pavlov. Cond. response bias0.20.32.90.70.9-0.7-0.2-0.2-0.10.21.7-0.10.4-0.40.4-0.10.3-0.10.10.3-1.00.2
Time in closed arm before self-admin0.61.04.70.61.2-1.1-0.8-0.7-1.2-0.62.2-0.80.7-0.70.91.30.80.90.8-0.3-1.5-0.9
Time in closed arm after self-admin0.10.10.30.1-0.00.1-0.0-0.2-0.50.00.3-0.00.3-0.30.20.60.10.4-0.3-0.10.4-0.1
Time in open arm before self-admin0.30.44.30.70.1-0.1-0.5-0.7-0.5-0.5-0.6-0.00.1-0.10.40.30.40.70.3-0.72.1-0.0
Time in open arm after self-admin0.40.50.80.70.7-0.9-0.8-0.7-0.6-0.8-0.3-0.70.6-0.60.60.50.60.50.9-0.80.7-0.5
Bone: periosteal estimation0.20.42.7-0.2-0.5-0.5-0.1-0.2-0.3-0.1-1.1-0.40.4-0.40.30.60.30.50.2-0.91.70.1
Bone: periosteal perimeter0.20.43.3-0.3-0.8-0.10.2-0.1-0.30.1-1.1-0.0-0.10.1-0.10.50.10.5-1.0-0.51.80.2
Bone: post-yield work0.71.13.7-1.9-1.61.01.21.41.61.0-1.40.8-0.60.6-0.7-1.1-0.7-1.2-0.10.1-0.60.4
Progressive ratio test 1 active lever presses0.40.63.3-1.8-1.10.81.01.00.61.0-1.10.2-0.20.20.1-1.00.1-0.40.60.3-0.9-0.1
Progressive ratio test 1 breakpoint0.40.63.3-1.8-1.10.81.01.00.61.0-1.00.2-0.20.20.1-1.00.1-0.40.60.3-1.0-0.1
Progressive ratio test 1 inactive lever presses0.41.03.1-1.7-1.21.11.31.30.31.3-0.10.7-0.70.7-0.6-1.1-0.6-1.0-0.71.0-1.40.3
Progressive ratio test 2 active lever presses0.20.31.9-1.4-0.70.30.70.4-0.20.8-0.4-0.40.5-0.50.5-0.00.50.20.80.6-0.2-0.5
Progressive ratio test 2 breakpoint0.30.42.1-1.5-0.80.40.70.5-0.10.9-0.5-0.30.4-0.40.4-0.10.40.20.70.8-0.2-0.5
Progressive ratio test 2 inactive lever presses0.72.35.9-2.4-2.11.72.01.91.52.0-1.11.3-1.31.3-1.0-1.7-1.1-1.2-1.01.2-0.80.9
Incentive Sensitization - Responses0.30.82.00.30.4-0.7-0.5-0.8-1.1-0.5-0.1-1.11.2-1.21.00.90.91.00.9-0.01.4-0.8
Incentive Sensitization - Breakpoint0.30.72.10.20.4-0.7-0.5-0.7-1.1-0.4-0.1-1.11.2-1.20.90.90.91.00.80.11.4-0.8
Sum of active levers in priming session hrs 5-60.40.42.6-0.30.5-0.2-0.3-0.1-0.2-0.20.8-0.40.7-0.70.60.10.70.20.8-0.2-1.6-0.9
Progressive ratio0.10.32.0-0.7-0.70.30.30.60.90.1-1.40.3-0.10.10.4-0.80.5-0.80.2-0.10.40.1
Food seeking constrained by brief footshock0.30.42.00.80.2-0.5-0.7-0.5-1.3-1.00.4-0.0-0.10.1-0.10.6-0.40.0-0.2-1.40.6-0.1
Seeking ratio, punishment vs. effort0.40.93.01.31.0-1.0-0.9-1.0-1.7-0.81.4-0.70.4-0.4-0.11.3-0.31.10.1-1.1-0.1-0.4
Retroperitoneal fat weight4.921.929.4-4.8-5.45.15.25.24.94.7-3.65.0-5.05.0-4.9-4.4-5.0-4.8-5.03.8-0.94.1
Reaction time number correct0.51.83.51.31.6-1.7-1.5-1.4-1.2-1.31.0-1.31.4-1.41.60.91.21.41.9-1.4-0.5-1.1
Reaction time mean minus median0.00.21.7-0.2-0.1-0.20.40.20.40.7-0.4-0.30.6-0.60.2-0.40.2-0.1-0.11.30.20.2
Reaction time mean minus median AUC0.00.20.90.10.4-0.5-0.1-0.30.00.20.1-0.70.9-0.90.6-0.00.40.40.40.70.1-0.3
Reaction time num false alarms0.10.20.70.10.2-0.20.00.30.50.00.80.3-0.30.3-0.4-0.4-0.4-0.5-0.2-0.3-0.80.4
Reaction time num false alarms AUC0.00.10.6-0.10.1-0.10.10.20.30.10.60.2-0.20.2-0.2-0.3-0.2-0.4-0.1-0.2-0.80.2
Reaction time trials correct on left0.51.83.51.31.6-1.7-1.5-1.4-1.2-1.31.0-1.31.4-1.41.60.91.21.41.9-1.4-0.5-1.1
Reaction time trials on left0.51.63.31.21.5-1.6-1.4-1.3-1.1-1.20.9-1.31.4-1.41.50.91.11.31.8-1.3-0.5-1.1
Reaction time mean0.61.32.8-0.9-1.20.81.41.21.61.6-1.70.8-0.50.5-0.9-1.1-0.7-1.0-0.31.60.81.3
Reaction time mean AUC0.61.53.3-1.1-1.30.91.61.31.81.8-1.60.9-0.60.6-0.9-1.3-0.7-1.1-0.21.80.61.4
Median of all reaction times1.42.24.4-1.2-1.71.31.71.62.11.9-2.01.4-1.11.1-1.3-1.5-1.1-1.4-0.51.60.91.8
Reaction time omissions0.50.92.6-1.1-1.00.91.31.11.21.6-0.50.5-0.40.4-0.5-1.2-0.5-0.8-0.11.50.40.9
Reaction time false alarm rate0.50.71.4-0.7-0.80.70.80.90.90.70.10.9-0.90.9-1.1-0.7-0.9-1.1-1.20.5-0.20.8
Reaction time premature initiation rate0.30.41.60.90.7-0.7-0.7-0.8-1.0-0.51.3-0.30.1-0.10.11.10.20.7-0.1-0.30.0-0.4
Reaction time premature initiations0.61.83.11.51.6-1.5-1.5-1.6-1.8-1.31.8-1.11.0-1.01.01.70.91.71.0-1.1-0.3-1.2
Std. dev. reaction times0.10.42.0-0.5-0.60.10.70.40.70.8-1.4-0.10.4-0.4-0.0-0.5-0.0-0.3-0.11.21.00.4
Reaction time trials completed0.51.63.31.21.5-1.6-1.4-1.3-1.1-1.20.9-1.31.4-1.41.50.91.11.31.8-1.3-0.5-1.1
Reaction time trials AUC0.62.14.01.41.7-1.8-1.6-1.5-1.2-1.40.9-1.41.6-1.61.71.01.31.42.0-1.5-0.5-1.2
Run reversals in cocaine runway, females0.30.41.6-0.6-0.90.50.40.3-0.20.1-1.30.2-0.40.4-0.80.0-0.90.3-0.6-0.01.10.0
Run reversals in cocaine runway, males0.40.52.2-0.3-0.30.1-0.0-0.5-1.5-0.1-0.8-0.20.2-0.20.51.10.51.20.40.31.1-0.8
Latency to leave start box in cocaine runway3.24.410.22.02.7-2.8-1.9-2.1-1.8-1.23.2-2.52.2-2.22.12.12.12.51.9-0.8-0.9-1.4
Latency to leave start box in cocaine runway, F1.21.55.81.41.5-1.9-0.9-1.2-0.9-0.12.4-1.41.1-1.11.11.11.11.61.1-0.00.1-0.1
Latency to leave start box in cocaine runway, M3.23.04.41.12.1-1.7-1.7-1.6-1.7-1.42.0-2.12.0-2.01.81.71.81.81.6-0.9-1.6-2.0
Std. dev. time between licks in bursts1.01.84.41.61.3-1.8-1.5-1.4-1.3-1.61.0-1.21.1-1.11.11.21.11.21.5-2.11.2-0.6
Total sessions with >9 infusions4.96.110.1-2.3-2.62.52.92.82.93.1-1.02.6-2.62.6-2.5-3.2-2.4-2.4-1.71.9-0.42.7
Short access day 1 total inactive lever presses0.40.72.3-1.1-0.70.61.11.11.01.50.40.3-0.30.3-0.5-1.3-0.4-0.7-0.70.8-1.00.8
Short access day 10 total inactive lever presses0.10.93.30.51.2-1.2-0.8-0.5-0.9-0.51.3-1.01.1-1.10.80.20.90.70.7-0.5-1.8-0.8
Short access day 1 total infusions3.46.711.4-2.5-2.52.63.12.93.13.4-0.82.6-2.62.6-2.4-3.2-2.5-2.8-1.92.5-1.12.6
Short access day 10 total infusions2.23.76.9-2.5-2.12.12.42.42.52.5-1.21.8-1.81.8-1.3-2.6-1.1-2.0-0.61.4-1.11.6
Short access total infusions3.14.48.2-2.2-2.02.12.52.42.72.7-0.52.1-2.12.1-1.8-2.9-1.8-2.2-1.11.7-1.42.0
Short access day 1 locomotion0.40.72.6-1.0-0.70.81.21.00.81.60.40.6-0.50.5-0.2-1.0-0.2-0.30.00.7-1.10.8
Short access day 10 total locomotion0.93.45.5-2.2-2.31.92.22.21.22.1-1.02.1-2.02.0-2.0-2.0-2.1-1.7-1.61.1-0.81.5
Short access total locomotion2.43.67.3-2.3-2.21.82.42.42.02.7-0.61.8-1.71.7-1.7-2.6-1.6-1.7-1.01.2-1.21.8
One hour access (0.3 mA shock)2.42.84.7-2.2-2.12.02.02.01.61.9-1.61.7-1.51.5-1.4-1.8-1.6-1.4-1.41.7-0.61.2
Compulsive drug intake0.00.10.40.40.30.0-0.2-0.1-0.0-0.20.30.00.1-0.1-0.1-0.0-0.30.2-0.70.1-0.40.0
One hour access (shock baseline)0.71.84.2-2.1-1.91.61.71.61.21.6-1.41.3-1.21.2-1.0-1.3-1.0-1.2-0.61.1-0.40.7
Social response proportion0.70.87.2-0.60.40.0-0.1-0.0-1.00.02.0-0.10.2-0.20.21.00.10.9-0.1-0.0-2.7-1.1
Social responses1.21.65.81.31.7-1.3-1.3-1.3-1.6-1.12.4-0.81.2-1.20.91.20.81.10.6-0.6-1.1-1.2
Social time0.71.17.7-0.70.7-0.00.1-0.0-0.40.72.8-0.50.6-0.60.50.40.50.61.10.8-2.7-1.0
Soleus weight1.44.19.3-0.00.5-2.2-1.4-1.5-2.4-1.6-1.0-2.52.5-2.52.42.32.32.32.2-3.00.5-2.2
Bone: stiffness0.61.13.60.20.2-1.2-0.8-0.8-1.0-1.0-0.4-1.21.2-1.21.30.91.10.91.2-1.91.0-0.8
Tibialis anterior weight0.10.54.0-1.4-0.80.10.60.80.50.6-0.20.1-0.00.00.0-0.3-0.2-0.3-0.0-0.5-2.0-0.2
Time to tail flick, vehicle, before self-admin0.30.42.9-0.3-0.80.60.30.20.40.1-1.50.30.1-0.10.20.00.1-0.1-0.40.01.70.2
Time to tail flick, vehicle, after self-admin0.81.72.5-1.2-1.61.41.41.41.41.3-1.31.3-1.31.3-1.2-1.2-1.1-1.2-1.31.40.81.2
Time to tail flick, test, before self-admin1.01.23.01.00.9-1.7-1.1-1.2-1.5-1.00.5-1.10.9-0.91.01.70.91.20.9-1.00.2-0.8
Time to tail flick, test, after self-admin0.30.31.4-0.3-0.50.80.40.4-0.10.40.10.5-0.50.5-0.50.3-0.8-0.0-1.20.70.20.4
Delta time to tail flick, vehicle, before/after SA1.21.32.2-1.0-1.11.21.21.20.91.1-0.51.0-1.31.3-1.5-1.0-1.4-1.2-1.31.4-0.21.0
Delta time to tail flick, test, before/after SA0.40.52.2-0.8-0.81.50.60.70.40.4-0.80.7-0.60.6-0.6-0.8-0.8-0.5-0.90.70.40.4
Tibia length0.10.20.9-0.20.10.20.30.40.70.50.70.2-0.20.2-0.2-0.5-0.3-0.5-0.51.0-0.90.2
Ambulatory time before self-admin0.10.30.80.60.3-0.8-0.5-0.5-0.5-0.6-0.5-0.50.7-0.70.60.10.60.30.7-0.50.9-0.2
Ambulatory time after self-admin1.52.44.61.01.4-1.3-1.7-1.6-2.1-1.81.3-1.71.8-1.81.62.01.51.61.3-1.20.1-1.8
Bone: tissue strength0.80.92.50.4-0.50.70.40.40.90.2-0.51.1-1.21.2-1.1-0.9-1.4-0.9-1.10.71.61.2
Total heroin consumption1.21.45.0-1.8-1.10.81.51.51.21.80.50.5-0.50.5-0.9-0.9-0.9-1.0-0.91.5-2.20.5
Bone: trabecular number0.20.41.41.20.9-1.0-0.7-0.6-0.0-0.41.1-0.30.3-0.30.40.20.40.20.9-0.70.70.3
Bone: trabecular spacing0.30.41.10.00.4-0.1-0.5-0.6-0.9-0.7-0.2-0.80.6-0.60.40.90.70.9-0.2-0.10.0-1.1
Bone: trabecular thickness1.72.34.21.91.6-2.0-1.8-1.7-1.1-1.70.6-1.51.7-1.71.71.11.51.11.3-2.01.0-0.8
Bone: trabecular tissue density0.81.42.31.10.9-1.2-1.2-1.2-1.1-1.3-0.8-1.21.3-1.31.31.11.51.11.2-1.21.2-0.8
Water consumed over 24 hours0.81.62.90.51.0-1.4-1.1-1.1-1.7-1.01.3-1.41.3-1.31.41.41.41.40.9-1.7-1.0-1.3
Number of responses in last shaping day4.55.99.8-3.0-2.82.83.02.82.43.1-1.52.3-2.22.2-2.2-2.7-2.2-2.4-2.12.2-0.71.9