Cfap54

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_27393147_27394543 0.04 0.02 1.8e-04 0.05 0.03 0.04 0.04 1.7e-06 7.5e-05 1.5e-05 2.8e-05
2 Brain isoform ratio XM_039080089.1 0.05 0.03 3.9e-05 0.06 0.05 0.04 0.06 7.9e-06 2.5e-05 3.2e-04 6.6e-06
3 PL gene expression Cfap54 0.22 0.09 0.0e+00 0.18 0.18 0.18 0.17 2.5e-19 4.9e-19 5.3e-19 1.4e-18
4 OFC isoform ratio XM_039080089.1 0.24 0.13 1.6e-03 0.1 0.11 0.05 0.12 2.3e-03 1.4e-03 2.2e-02 1.0e-03
5 PL isoform ratio XM_039080084.1 0.04 0.02 1.5e-03 0.03 0.01 0.02 0.01 2.8e-04 4.6e-02 2.7e-03 9.0e-03
6 LHb gene expression Cfap54 0.47 0.13 2.7e-06 0.22 0.07 0.04 0.2 5.5e-06 8.2e-03 5.0e-02 1.4e-05
7 Eye gene expression Cfap54 0.67 0.12 7.1e-05 -0.01 0.03 -0.01 0.01 4.6e-01 1.2e-01 5.2e-01 2.2e-01
8 BLA isoform ratio XM_039080089.1 0.22 0.13 6.7e-05 0.05 0.07 0.09 0.05 1.7e-03 1.7e-04 2.5e-05 8.3e-04
9 NAcc intron excision ratio chr7_27492385_27496701 0.11 0.04 2.8e-10 0.09 0.09 0.1 0.1 3.5e-10 3.7e-10 3.4e-11 1.1e-11
10 IL isoform ratio XM_039080086.1 0.25 0.1 8.9e-05 0.1 0.18 0.16 0.17 2.5e-03 4.1e-05 1.4e-04 8.6e-05
11 Brain intron excision ratio chr7_27492385_27496701 0.13 0.05 5.5e-10 0.09 0.12 0.11 0.12 4.3e-09 2.0e-11 3.2e-10 3.7e-11
12 Brain intron excision ratio chr7_27492385_27495660 0.12 0.05 2.3e-09 0.09 0.11 0.1 0.11 6.7e-09 9.6e-11 1.5e-09 1.6e-10
13 pVTA gene expression Cfap54 0.13 0.06 7.2e-04 0.09 0.03 0.04 0.05 7.5e-05 1.3e-02 5.6e-03 2.4e-03
14 Adipose gene expression Cfap54 0.11 0.04 2.3e-09 0.08 0.07 0.07 0.08 4.1e-09 1.1e-08 1.0e-08 3.0e-09
15 IL gene expression Cfap54 0.23 0.13 4.8e-03 0.11 0.11 0.13 0.13 1.3e-03 1.2e-03 4.3e-04 6.3e-04
16 OFC gene expression Cfap54 0.37 0.12 8.7e-06 0.13 0.09 0.14 0.15 5.9e-04 3.5e-03 3.1e-04 1.9e-04
17 Brain gene expression Cfap54 0.19 0.07 7.7e-14 0.14 0.13 0.14 0.13 8.8e-13 4.5e-12 3.8e-13 4.6e-12
18 IL isoform ratio XM_039080089.1 0.42 0.12 2.2e-08 0.32 0.34 0.34 0.33 2.2e-08 5.9e-09 5.0e-09 9.6e-09
19 BLA gene expression Cfap54 0.11 0.06 4.4e-04 0.05 0.06 0.05 0.05 1.2e-03 3.4e-04 1.1e-03 8.0e-04
20 PL isoform ratio XM_039080089.1 0.23 0.08 0.0e+00 0.19 0.2 0.2 0.15 3.0e-20 2.1e-21 2.5e-21 2.0e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.61.02.01.0-0.5-1.1-0.8-1.2-1.11.20.2-1.10.8-0.80.8-1.31.2-1.41.2-1.10.90.9-0.8
Area under the delay curve0.50.51.9-0.4-0.21.00.30.41.0-0.90.41.0-0.51.4-1.30.9-0.70.8-0.50.2-0.20.2-0.3
BMI with tail0.72.24.21.0-0.3-2.0-0.9-1.1-1.72.00.1-1.80.8-1.31.4-1.71.3-1.62.0-1.80.91.7-1.8
BMI without tail0.40.92.00.20.8-1.20.4-0.1-1.11.4-1.2-1.1-0.3-0.70.7-1.00.3-0.81.1-1.4-0.31.0-1.2
Body weight0.93.713.8-2.03.1-1.51.92.1-1.42.3-3.7-1.5-2.1-2.22.2-1.60.1-0.51.5-2.3-1.8-0.1-0.5
Weight adjusted by age0.60.72.4-0.51.4-0.70.90.3-0.61.0-1.2-0.5-0.1-1.61.5-0.8-0.0-0.30.5-0.4-0.3-0.30.8
Bone surface0.30.61.30.8-0.8-0.7-1.0-0.8-0.80.60.5-0.70.7-0.10.1-0.70.9-0.90.9-0.80.71.2-1.1
Bone volume0.91.62.31.1-1.0-1.4-1.3-1.2-1.51.40.6-1.51.0-0.80.8-1.31.4-1.51.5-1.41.11.4-1.5
Breakpoint value in progressive ratio session0.70.82.91.1-1.7-0.7-1.4-1.0-0.70.01.3-0.60.80.2-0.2-0.20.8-0.70.5-0.50.80.9-1.2
Number of licking bursts0.40.50.90.2-0.2-0.7-0.4-0.5-0.70.90.2-0.70.7-0.90.9-0.90.7-0.80.9-0.60.60.3-0.1
Context. condit. distance diff. score0.40.51.5-0.91.1-0.40.61.2-0.40.6-1.2-0.4-0.2-1.11.0-0.2-0.20.20.20.2-0.6-0.30.7
Locomotion velocity, session 10.70.71.6-0.6-0.21.10.20.51.1-1.30.21.2-0.51.3-1.31.1-0.71.0-0.90.7-0.6-0.30.3
Locomotion distance, session 10.10.10.2-0.0-0.10.40.1-0.00.4-0.30.50.50.20.4-0.40.4-0.20.3-0.1-0.00.10.2-0.1
Locomotion velocity, session 20.91.01.8-1.30.81.10.91.31.1-0.8-0.71.1-1.10.7-0.61.3-1.11.3-1.00.9-1.1-1.00.7
Locomotion distance, session 20.20.20.90.3-0.3-0.1-0.2-0.1-0.10.60.8-0.10.60.00.10.20.10.10.7-0.90.50.9-0.8
Locomotion velocity, session 30.10.10.6-0.5-0.3-0.1-0.40.4-0.10.2-0.3-0.1-0.1-0.40.40.2-0.20.1-0.10.4-0.8-0.0-0.0
Locomotion distance, session 30.40.51.8-1.30.1-0.50.11.2-0.50.9-0.4-0.5-0.0-1.31.3-0.40.00.10.5-0.5-0.4-0.40.3
Stereotopy head waving bouts, day 31.01.12.71.5-1.5-0.8-1.6-1.4-0.70.31.6-0.81.40.3-0.2-0.10.9-0.80.7-0.51.41.4-1.3
Stereotopy head waving duration, day 30.50.61.51.2-1.0-0.1-1.0-1.1-0.0-0.41.0-0.10.71.0-0.90.30.3-0.3-0.10.20.61.0-1.1
Locomotion velocity, session 70.60.62.4-1.50.50.60.81.50.8-0.5-0.50.7-0.90.1-0.10.7-0.90.9-0.50.1-1.2-0.70.5
Locomotion distance, session 70.91.13.8-1.90.81.01.12.01.1-0.7-0.71.0-1.00.3-0.20.8-1.11.3-0.80.5-1.3-1.00.9
Stereotopy head waving bouts, day 71.21.42.5-1.00.91.01.31.21.1-1.1-1.11.0-1.30.7-0.81.3-1.31.2-1.41.6-1.4-1.20.9
Stereotopy head waving duration, day 70.70.82.2-0.50.50.70.90.80.7-0.8-0.90.7-1.10.5-0.51.1-1.00.9-1.21.5-1.1-1.00.7
Locomotion velocity, session 81.21.43.3-1.61.41.11.41.81.1-0.7-1.21.1-1.10.6-0.61.2-1.51.5-0.80.7-1.4-0.70.8
Locomotion distance, session 80.40.71.9-0.70.8-0.70.31.0-0.81.3-0.5-0.70.3-1.41.4-0.50.1-0.11.2-1.1-0.10.5-0.2
Degree of sensitization distance1.21.22.3-0.50.81.41.10.51.4-1.5-0.61.4-1.01.5-1.51.1-1.11.1-1.21.2-0.9-0.70.7
Degree of sensitization stereotypy1.92.03.8-1.41.11.21.61.51.3-1.2-1.41.2-1.60.5-0.61.4-1.61.5-1.71.9-1.7-1.81.4
Conditioned locomotion0.91.02.00.6-0.8-1.3-1.0-0.4-1.40.80.7-1.30.6-1.00.9-1.31.4-1.11.0-1.21.00.5-0.7
Cocaine response after cond. corrected3.23.65.4-2.02.22.22.31.72.2-1.6-1.72.2-2.21.4-1.41.6-1.92.1-1.81.6-1.8-2.01.7
Cocaine response after cond. not corrected2.42.74.3-1.61.62.11.81.32.1-1.5-1.12.1-1.71.5-1.41.5-1.71.9-1.61.4-1.5-1.51.3
Cocaine response before conditioning1.21.44.11.3-2.0-1.0-1.9-1.2-0.90.51.7-1.01.5-0.30.3-0.81.1-1.00.8-0.91.11.4-1.3
Saline control response0.30.31.0-0.5-0.40.60.00.40.5-0.80.50.6-0.51.0-0.91.0-0.60.8-0.50.3-0.30.1-0.4
Bone: connectivity density0.30.51.4-0.21.10.70.7-0.00.6-0.4-1.20.7-0.70.6-0.60.6-0.60.4-0.60.8-0.6-0.60.8
Bone: cortical apparent density0.91.14.6-0.91.2-1.01.00.9-1.01.4-1.0-1.0-0.2-2.12.1-0.70.0-0.40.9-0.80.0-0.70.9
Bone: cortical area0.50.81.90.1-0.1-1.2-0.7-0.2-1.21.3-0.3-1.20.2-1.41.4-1.31.0-1.00.9-0.80.00.2-0.4
Bone: cortical porosity0.40.52.20.2-0.60.5-0.2-0.00.6-1.00.10.5-0.71.5-1.50.2-0.10.4-0.90.3-0.60.1-0.8
Bone: cortical porosity0.30.31.50.5-1.10.0-0.6-0.50.1-0.50.50.0-0.21.1-1.0-0.20.4-0.1-0.3-0.2-0.10.6-1.2
Bone: cortical thickness0.20.31.1-0.40.2-0.7-0.20.2-0.70.8-0.5-0.7-0.4-1.01.0-0.90.6-0.50.4-0.4-0.2-0.40.0
Bone: cortical thickness0.40.41.0-0.80.60.50.50.70.5-0.5-0.90.5-1.00.4-0.40.2-0.20.4-0.80.7-0.9-1.00.7
Bone: cortical tissue density0.81.14.3-0.91.3-0.91.10.9-0.91.3-1.1-0.9-0.2-2.12.0-0.6-0.0-0.40.8-0.8-0.0-0.70.9
Condit. Reinf. active minus inactive responses2.12.45.82.1-2.1-0.8-2.3-2.0-0.70.42.4-0.72.00.4-0.3-0.81.7-1.21.0-0.82.02.1-1.6
Condit. Reinf. active-inactive response ratio2.22.45.12.1-2.1-0.9-2.2-1.9-1.00.62.3-1.02.00.1-0.1-1.11.9-1.41.0-0.92.01.9-1.7
Condit. Reinf. active responses1.72.16.12.2-2.20.2-2.2-1.90.3-0.72.50.31.61.7-1.60.30.9-0.40.10.01.41.9-1.6
Condit. Reinf. inactive responses0.91.13.50.6-0.61.3-0.4-0.41.4-1.50.61.3-0.21.9-1.81.4-0.80.9-1.11.1-0.4-0.1-0.0
Incentive salience index mean2.02.45.42.2-2.0-0.7-2.2-2.0-0.60.52.3-0.72.10.5-0.4-0.81.6-1.11.1-1.11.82.3-1.9
Condit. Reinf. lever presses0.71.02.51.5-0.9-0.5-1.1-1.4-0.50.71.0-0.51.30.10.0-0.71.0-0.91.0-1.01.01.6-1.2
Condit. Reinf. active minus inactive responses0.81.01.91.0-1.2-1.1-1.4-0.9-1.20.80.9-1.10.8-0.70.7-1.01.4-1.10.7-0.40.90.7-0.8
Condit. Reinf. active-inactive response ratio0.10.10.50.3-0.3-0.2-0.5-0.2-0.30.20.4-0.20.1-0.10.1-0.50.7-0.40.10.20.20.1-0.3
Condit. Reinf. active responses1.72.33.91.2-1.6-1.8-2.0-1.1-1.81.41.4-1.81.5-1.41.4-1.52.0-1.61.4-1.21.51.2-1.2
Condit. Reinf. inactive responses0.91.11.70.7-1.1-1.3-1.3-0.7-1.20.91.0-1.31.1-1.11.1-1.01.2-1.01.1-1.21.10.7-0.5
Condit. Reinf. lever presses0.10.20.6-0.8-0.0-0.3-0.00.8-0.30.1-0.4-0.3-0.7-0.50.5-0.10.10.1-0.1-0.3-0.4-0.70.2
Condit. Reinf. lever reinforcers received1.31.93.21.1-1.4-1.6-1.8-1.0-1.71.31.2-1.61.3-1.41.4-1.31.7-1.41.2-1.01.31.0-1.0
Conditioned reinforcement - actives1.71.73.51.7-1.3-1.2-1.3-1.9-1.01.01.2-1.11.3-0.60.7-1.31.4-1.51.2-1.51.31.3-1.3
Conditioned reinforcement - inactives0.91.01.7-0.20.71.20.90.31.2-1.0-0.71.1-1.01.0-1.01.3-1.31.1-1.20.7-1.1-0.80.6
Conditioned locomotion0.00.00.4-0.0-0.2-0.10.1-0.20.10.1-0.1-0.1-0.0-0.10.1-0.2-0.0-0.10.0-0.6-0.30.1-0.2
Patch foraging indifference point 0 sec0.30.51.0-0.20.70.60.60.00.6-0.9-0.70.6-1.00.8-0.80.9-0.70.6-0.91.0-0.8-0.70.4
Patch foraging indifference point AUC1.01.12.9-1.31.70.91.71.31.0-0.6-1.40.9-1.30.7-0.70.8-1.01.0-0.50.9-1.0-0.80.8
Delay disc. indifference point, 0s delay0.40.41.90.0-0.40.6-0.30.10.7-0.80.70.6-0.21.4-1.30.7-0.30.6-0.4-0.20.00.5-0.8
Delay disc. indifference point, 16s delay0.30.31.00.1-0.8-0.1-0.4-0.1-0.00.30.8-0.10.50.4-0.3-0.30.4-0.30.5-0.60.60.9-1.0
Delay disc. indifference point, 2s delay0.80.91.6-1.10.41.30.81.11.2-1.2-0.21.3-0.81.3-1.31.1-1.11.1-0.80.4-0.7-0.20.3
Delay disc. indifference point, 24s delay0.40.41.60.8-0.6-0.1-0.3-1.0-0.10.20.5-0.10.40.6-0.6-0.30.3-0.50.5-0.70.31.3-1.1
Delay disc. indifference point, 4s delay1.61.74.0-0.70.31.80.90.71.6-1.7-0.31.8-1.42.0-2.01.6-1.41.5-1.50.7-1.0-0.70.3
Delay disc. indifference point, 8s delay0.40.41.2-0.40.30.70.60.50.7-0.7-0.20.7-0.81.1-1.00.8-0.90.8-0.50.3-0.3-0.1-0.1
Indifference point function ln k0.20.21.30.4-1.1-0.0-0.9-0.8-0.0-0.30.7-0.00.20.00.0-0.10.4-0.2-0.2-0.90.10.0-0.3
Indifference point function log k0.20.21.30.4-1.1-0.0-0.9-0.8-0.0-0.30.7-0.00.20.00.0-0.10.4-0.2-0.2-0.90.10.0-0.3
Patch foraging total patch changes 0 sec0.30.51.1-0.30.80.60.70.10.6-0.8-0.80.6-1.10.6-0.60.8-0.70.6-0.80.9-0.8-0.80.5
Patch foraging total patch changes 12 sec0.70.93.8-1.21.90.31.61.10.4-0.2-1.70.3-1.40.1-0.10.3-0.60.5-0.30.6-0.9-0.90.7
Patch foraging total patch changes 18 sec0.50.61.7-1.01.00.71.11.30.5-0.7-0.70.7-1.10.3-0.40.4-0.40.6-0.40.7-0.6-1.00.8
Patch foraging total patch changes 24 sec0.81.02.3-0.91.31.01.10.91.0-1.1-1.20.9-1.51.1-1.20.8-0.80.9-0.80.8-1.2-0.80.5
Patch foraging total patch changes 6 sec0.20.31.20.40.10.3-0.0-0.30.2-0.70.10.3-0.41.1-1.10.7-0.40.4-0.50.6-0.20.2-0.4
Patch foraging time to switch 0 sec1.11.72.71.6-0.7-1.6-1.2-1.1-1.61.40.7-1.71.3-1.21.2-1.61.4-1.61.1-0.51.61.0-0.9
Patch foraging water rate 0 sec0.30.52.50.0-0.3-0.6-0.4-0.5-0.40.80.4-0.50.5-0.60.7-0.60.7-0.51.0-1.60.30.8-0.7
Patch foraging water rate 12 sec0.20.31.2-0.90.20.60.30.60.4-0.4-0.50.6-0.60.8-0.80.5-0.40.6-0.5-0.4-1.10.2-0.4
Patch foraging water rate 18 sec0.71.02.11.1-1.2-0.9-1.2-1.4-1.01.01.1-1.01.3-1.01.0-0.50.5-0.80.7-1.20.60.8-0.8
Patch foraging water rate 24 sec0.81.15.00.00.0-1.0-0.2-0.3-1.11.3-0.0-1.00.6-1.61.6-1.20.9-0.91.3-2.20.20.6-0.4
Patch foraging water rate 6 sec1.42.16.7-0.50.2-1.6-0.30.2-1.52.1-0.4-1.60.7-2.22.3-1.81.3-1.22.0-2.60.30.8-0.7
Seeking ratio, delayed vs. immediate footshock0.50.62.0-0.70.11.30.40.71.1-1.00.01.1-0.81.4-1.30.8-0.50.7-0.4-0.1-0.4-0.3-0.1
Distance traveled before self-admin0.60.62.7-0.11.1-0.60.60.0-0.91.0-0.8-0.90.4-1.61.6-0.6-0.0-0.30.40.50.1-0.41.0
Distance traveled after self-admin0.30.31.4-1.20.60.30.71.00.20.4-0.30.1-0.1-0.70.70.0-0.30.50.10.2-0.4-0.50.6
Extensor digitorum longus weight1.56.010.52.7-2.7-2.8-3.2-2.7-2.82.22.1-2.72.3-0.91.0-1.92.8-2.52.1-2.42.12.7-3.0
Bone: elastic displacement0.40.51.7-0.1-0.60.8-0.50.30.8-1.10.60.8-0.11.3-1.30.8-0.30.7-0.90.8-0.2-0.1-0.0
Bone: elastic work0.40.51.70.3-1.20.5-0.9-0.40.6-1.00.80.50.01.3-1.30.60.10.2-0.80.7-0.10.2-0.4
Bone: endosteal estimation1.02.33.71.9-1.4-1.5-1.7-1.7-1.51.51.3-1.51.9-0.90.9-1.41.7-1.61.5-1.11.61.7-1.4
Bone: endosteal perimeter0.50.92.00.7-0.1-1.1-0.8-0.6-1.21.40.1-1.10.7-1.31.3-1.20.9-1.01.3-1.20.60.7-0.6
Epididymis fat weight0.92.16.1-2.52.2-0.31.62.2-0.40.9-2.4-0.3-1.0-1.91.80.1-1.00.8-0.00.6-1.5-1.31.5
Delta time in closed arm before/after self-admin0.10.10.20.50.30.10.4-0.20.10.1-0.50.10.00.1-0.1-0.50.0-0.1-0.30.4-0.20.00.1
Delta time in open arm before/after self-admin0.80.82.0-0.90.50.80.60.50.8-1.0-0.40.8-1.11.1-1.11.4-1.21.0-0.80.9-0.8-0.60.1
Diff in mean of infusions in LGA sessions1.01.13.71.3-1.90.4-1.4-1.20.3-1.21.70.30.41.7-1.61.00.2-0.0-0.60.10.40.7-1.1
Delay discount exponential model param0.60.61.90.6-0.0-1.1-0.6-0.5-1.11.0-0.1-1.10.7-1.41.3-1.00.9-0.90.6-0.30.4-0.00.2
Extinction: sum of active levers before priming0.70.73.00.6-0.70.9-0.4-0.90.8-1.10.80.90.31.7-1.71.1-0.40.3-0.60.50.10.7-0.6
Active lever presses in extinction session 60.70.72.61.4-0.8-0.4-0.5-1.5-0.20.10.7-0.30.61.0-0.90.00.4-0.60.4-0.60.61.6-1.5
Bone: final force0.81.22.90.9-1.1-1.2-1.1-1.0-1.21.10.5-1.20.8-0.80.8-1.71.6-1.51.1-0.80.70.8-1.1
Bone: final moment0.71.23.00.9-1.3-1.1-1.2-0.9-1.11.00.7-1.10.8-0.60.6-1.71.7-1.51.0-0.90.70.9-1.2
Food consumed during 24 hour testing period2.02.44.1-2.01.01.81.31.91.8-1.6-0.91.8-1.71.1-1.11.8-1.81.9-1.61.0-1.7-1.51.3
Glucose0.10.10.5-0.10.0-0.3-0.1-0.1-0.30.40.1-0.30.2-0.20.3-0.60.4-0.40.6-0.70.30.3-0.3
Heart weight0.10.20.6-0.50.00.5-0.20.20.2-0.2-0.40.4-0.60.4-0.30.4-0.10.4-0.50.3-0.8-0.3-0.1
Delay discount hyperbolic model param0.80.82.10.7-0.1-1.2-0.7-0.7-1.21.10.0-1.20.9-1.41.4-1.11.1-1.00.8-0.30.60.20.1
Intermittent access intake day 1-15 change1.41.32.31.5-1.2-1.2-1.4-1.5-1.10.91.2-1.31.3-0.50.6-1.01.2-1.20.9-0.61.21.3-1.4
Intermittent access intake escalation0.50.50.90.9-1.0-0.7-0.9-0.9-0.60.40.9-0.80.8-0.10.2-0.40.7-0.70.3-0.00.70.8-1.0
Intermittent access intake escalation 20.90.92.81.4-1.2-0.7-1.3-1.7-0.60.21.3-0.70.90.0-0.0-0.51.0-1.00.5-0.31.01.0-1.1
Intermitt. access day 1 inactive lever presses5.45.814.1-1.50.03.00.81.73.0-3.5-0.02.9-1.83.8-3.73.1-2.22.8-2.92.2-1.8-1.30.7
Intermitt. access day 15 inactive lever presses4.75.18.7-2.10.92.81.52.22.5-3.0-1.12.6-2.12.5-2.52.7-2.32.6-2.62.3-2.4-1.71.5
Intermitt. access escalation Index0.20.10.5-0.30.30.30.20.50.1-0.3-0.50.0-0.2-0.20.10.2-0.10.3-0.60.7-0.3-0.60.7
Intermittent access day 1 total infusions0.20.30.90.00.50.80.80.10.9-0.5-0.00.8-0.10.8-0.70.4-0.70.3-0.2-0.1-0.10.30.2
Intermittent access day 15 total infusions0.20.21.00.7-0.10.10.1-0.50.20.10.5-0.10.60.3-0.30.0-0.1-0.20.2-0.10.41.0-0.7
Intermittent access terminal intake (last 3 days)0.30.41.71.0-0.2-0.1-0.1-1.00.10.40.7-0.20.80.2-0.2-0.20.2-0.50.6-0.50.71.3-0.9
Intermittent access total infusions0.20.21.10.80.10.40.3-0.60.60.00.60.40.60.6-0.50.2-0.3-0.10.3-0.30.51.1-0.5
Intermittent access day 1 locomotion1.71.83.6-1.41.51.61.91.61.8-1.1-1.31.5-1.40.9-0.91.2-1.71.3-1.00.5-1.3-1.11.2
Intermittent access day 15 total locomotion0.10.20.4-0.20.30.50.60.30.6-0.5-0.20.4-0.30.6-0.60.3-0.50.3-0.3-0.0-0.40.1-0.0
Intermittent access total locomotion0.30.31.0-0.30.40.80.70.21.0-0.6-0.20.8-0.40.8-0.80.6-0.70.6-0.50.2-0.5-0.00.1
Intermittent access standard deviation0.20.20.70.30.5-0.00.5-0.50.30.50.10.10.6-0.10.1-0.1-0.1-0.30.6-0.30.60.8-0.2
Left kidney weight0.41.04.3-1.51.6-0.61.11.2-0.71.0-2.1-0.6-1.1-1.31.2-0.4-0.10.10.3-0.0-1.3-0.50.3
Right kidney weight0.51.34.8-2.21.7-0.21.31.9-0.20.5-2.1-0.2-1.5-1.11.0-0.1-0.50.60.00.3-1.6-1.10.7
Cocaine induced anxiety2.22.54.3-1.71.81.31.91.71.1-0.9-1.91.2-1.6-0.1-0.01.4-1.81.6-1.61.7-1.8-2.12.1
Post-drug Anxiety0.70.82.2-0.91.10.61.11.00.4-0.2-1.00.5-0.7-0.60.60.7-1.00.8-0.71.1-0.8-1.31.5
Baseline Anxiety1.01.01.81.2-1.2-1.1-1.4-1.0-1.00.71.1-1.01.1-0.50.5-1.11.3-1.21.0-0.61.20.9-0.8
Tail length1.34.016.4-2.83.5-0.23.03.0-0.31.0-4.0-0.2-2.8-1.51.4-0.4-1.20.70.1-0.8-2.7-1.41.1
Length with tail2.38.330.2-4.44.90.34.14.50.20.9-5.50.3-3.9-2.12.0-0.0-1.81.4-0.2-0.8-3.8-2.62.1
Length without tail1.22.68.8-3.02.40.21.82.80.30.4-2.80.2-2.1-1.41.30.1-0.80.8-0.0-0.5-2.0-1.71.2
Times rat made contact with spout1.01.22.81.2-1.6-0.4-1.3-1.6-0.40.11.7-0.41.10.7-0.6-0.50.8-0.90.8-1.11.21.6-1.7
Lifetime Intake0.30.31.10.8-0.1-0.20.1-0.60.00.70.6-0.20.9-0.30.4-0.50.2-0.60.8-0.80.81.1-0.5
Liver weight, left0.81.33.2-1.31.80.91.71.10.8-0.6-1.70.9-1.30.1-0.10.9-1.21.0-0.90.6-1.5-1.11.2
Liver weight, right1.22.05.3-0.50.8-1.90.40.3-1.92.3-1.0-1.90.6-2.32.3-1.71.0-1.21.5-1.50.30.6-0.4
Locomotor activity0.60.91.9-0.0-0.2-1.3-0.6-0.2-1.40.8-0.3-1.3-0.1-0.80.7-1.41.2-1.21.2-1.2-0.00.9-1.3
Locomotor testing distance0.61.02.51.0-1.2-1.1-1.3-1.0-1.10.30.7-1.10.5-0.10.1-1.11.2-1.31.0-1.00.41.3-1.6
Locomotor testing rearing0.61.02.01.3-1.1-0.9-1.0-1.2-0.70.00.8-1.00.70.2-0.3-1.31.4-1.40.9-0.80.81.1-1.1
Locomotion in novel chamber0.20.30.90.3-0.60.5-0.1-0.20.7-0.50.70.60.21.0-0.90.20.00.10.2-0.40.10.8-0.6
Locomotion in novel chamber post-restriction0.60.72.0-0.21.20.91.40.21.0-0.5-1.10.7-0.60.7-0.70.8-1.10.7-0.81.1-0.7-0.40.7
Fecal boli incidents, locomotor time 10.20.20.7-0.30.6-0.10.60.4-0.20.5-0.6-0.1-0.4-0.10.2-0.30.1-0.30.7-0.80.10.1-0.2
Change in fecal boli incidents, locomotor task0.30.30.80.3-0.70.3-0.7-0.20.3-0.70.70.30.40.4-0.50.6-0.30.6-0.80.9-0.10.00.2
Time >=10cm from walls, locomotor time 10.00.10.4-0.1-0.1-0.1-0.0-0.0-0.2-0.2-0.1-0.1-0.2-0.1-0.0-0.00.3-0.2-0.20.7-0.1-0.30.2
Bouts of movement, locomotor time 10.60.71.50.6-0.2-1.2-0.4-0.5-1.01.20.3-1.20.9-1.11.1-0.90.6-0.80.8-0.60.80.6-0.5
Total resting periods, locomotor time 10.60.61.20.6-0.4-1.1-0.5-0.5-1.01.10.4-1.10.9-1.01.1-0.90.7-0.80.7-0.50.80.5-0.4
Rest time, locomotor task time 10.10.21.11.1-0.1-0.0-0.2-1.0-0.1-0.1-0.1-0.00.10.4-0.4-0.10.2-0.4-0.20.40.10.2-0.3
Distance moved, locomotor task time 10.60.72.00.5-1.2-0.6-1.3-0.7-0.60.21.4-0.60.90.1-0.0-0.50.8-0.60.7-0.90.91.1-1.1
Vertical activity count, locomotor time 11.41.52.30.3-1.1-1.5-1.5-0.2-1.51.21.3-1.51.1-1.11.1-1.21.2-1.01.3-1.51.01.3-1.3
Time >=10cm from walls, locomotor time 20.20.20.6-0.1-0.30.5-0.20.10.5-0.70.50.5-0.10.7-0.70.6-0.20.4-0.40.80.0-0.10.0
Bouts of movement, locomotor time 20.91.02.21.5-0.7-1.1-0.7-1.5-1.20.80.4-1.10.8-0.10.1-1.10.8-1.30.7-1.20.91.3-1.2
Total resting periods, locomotor time 21.61.73.11.8-1.0-1.5-1.1-1.7-1.61.10.7-1.51.2-0.40.4-1.41.2-1.61.1-1.31.31.7-1.5
Rest time, locomotor task time 22.93.36.62.6-1.6-2.0-1.9-2.3-2.01.71.3-2.02.0-1.21.2-1.92.0-2.21.5-1.11.81.7-1.6
Distance moved, locomotor task time 21.21.44.4-2.11.11.11.11.71.1-1.0-0.81.1-1.20.5-0.51.2-1.31.5-1.00.6-1.2-1.31.0
Vertical activity count, locomotor time 20.30.32.1-1.40.2-0.2-0.11.3-0.40.1-0.0-0.2-0.7-0.10.2-0.10.10.40.3-1.1-0.3-0.1-0.7
Light reinforcement 10.81.54.2-1.81.7-0.21.51.8-0.20.6-2.1-0.1-0.7-1.71.6-0.1-0.60.4-0.10.7-1.4-1.41.7
Light reinforcement 20.40.50.9-0.70.40.60.70.90.6-0.7-0.70.7-0.60.5-0.50.9-0.90.8-0.81.0-0.8-0.80.8
Bone: marrow area1.02.13.51.9-1.3-1.4-1.6-1.7-1.51.51.2-1.41.8-0.80.9-1.31.6-1.51.5-1.01.61.7-1.3
Bone: maximum diameter0.50.91.80.8-0.2-1.2-0.8-0.6-1.21.3-0.0-1.20.6-1.31.3-1.21.0-1.11.2-1.10.40.7-0.6
Bone: maximum force0.61.12.21.0-1.4-1.1-1.2-1.1-1.10.90.7-1.10.8-0.60.7-1.31.5-1.40.9-0.50.70.8-1.0
Bone: maximum moment0.71.22.91.1-1.7-1.1-1.5-1.1-1.10.81.0-1.10.9-0.40.5-1.41.6-1.40.9-0.60.80.9-1.2
Mean time between licks in bursts2.02.74.11.3-1.5-1.9-1.5-1.0-1.91.81.4-1.91.6-1.31.3-1.71.8-1.71.9-2.01.71.7-1.7
Mean num. licks in bursts0.60.72.50.7-1.20.6-0.7-0.50.6-1.01.30.60.21.6-1.50.8-0.20.4-0.60.20.30.8-1.0
Cd content in liver3.53.87.60.2-0.6-2.4-1.3-0.2-2.42.80.7-2.41.5-2.52.6-2.72.1-1.92.7-2.41.71.2-1.3
Co content in liver0.40.51.3-1.11.10.41.11.10.4-0.1-0.90.4-0.9-0.20.20.2-0.50.6-0.1-0.5-0.6-0.70.7
Cu content in liver0.20.30.9-0.70.70.20.80.70.2-0.3-0.90.2-0.90.5-0.50.2-0.40.4-0.2-0.2-0.7-0.2-0.2
Fe content in liver0.40.51.11.0-0.6-0.7-0.2-1.1-0.70.60.4-0.70.6-0.50.5-0.90.8-1.00.6-0.70.50.7-0.7
K content in liver0.40.41.50.20.10.60.4-0.30.6-0.9-0.10.6-0.71.2-1.20.8-0.50.4-0.70.3-0.3-0.0-0.3
Mg content in liver0.20.20.80.5-0.40.2-0.1-0.50.3-0.70.30.2-0.30.9-0.90.5-0.20.1-0.40.0-0.00.3-0.5
Mn content in liver1.01.22.41.4-1.5-1.0-1.4-1.3-1.00.41.2-1.00.90.00.0-0.91.3-1.20.7-0.81.01.2-1.5
Na content in liver0.91.02.0-0.21.00.90.80.11.0-1.2-1.11.0-1.40.9-1.01.0-1.10.8-1.31.3-1.1-0.90.7
Rb content in liver1.01.22.5-0.70.81.21.00.61.2-1.2-0.91.2-1.21.3-1.31.6-1.31.3-1.30.8-1.1-0.80.5
Se content in liver0.10.10.5-0.7-0.20.40.30.60.4-0.50.10.4-0.20.1-0.1-0.30.10.2-0.00.3-0.3-0.20.2
Sr content in liver2.32.13.4-1.61.41.51.31.71.5-1.0-1.51.5-1.31.0-0.91.7-1.71.8-1.61.6-1.8-1.11.0
Zn content in liver0.10.10.5-0.40.70.20.70.40.20.0-0.70.2-0.5-0.00.00.2-0.40.3-0.1-0.2-0.5-0.20.1
Bone: minimum diameter1.52.76.40.1-0.3-2.1-0.9-0.1-2.22.4-0.1-2.20.9-2.52.5-2.41.8-1.72.0-1.70.70.9-0.9
Time in familiar zone, hab. session 10.50.41.7-1.30.60.60.41.10.6-0.2-0.60.5-0.7-0.10.10.6-0.60.8-0.40.6-0.7-0.80.7
Time in novel zone, hab. session 10.50.51.11.1-0.8-0.7-0.6-1.0-0.70.40.8-0.70.8-0.30.3-0.50.6-0.80.4-0.30.90.5-0.6
Total zone transitions, hab. session 13.65.18.91.5-2.0-2.4-2.3-1.5-2.42.22.0-2.32.3-1.31.3-2.52.6-2.22.6-3.02.12.8-2.7
Total locomotion distance, hab. session 14.66.511.52.6-2.3-2.6-2.7-2.6-2.62.22.5-2.62.8-1.21.2-2.22.6-2.62.8-3.02.53.4-3.0
Locomotion velocity, hab. session 15.78.115.63.0-2.8-2.8-3.1-2.9-2.82.32.9-2.83.2-1.11.1-2.53.0-2.93.1-3.32.73.9-3.5
Time in familiar zone, hab. session 20.00.00.20.10.1-0.10.10.1-0.10.2-0.3-0.1-0.00.0-0.00.4-0.30.2-0.20.5-0.30.1-0.1
Time in novel zone, hab. session 20.10.10.30.2-0.50.0-0.4-0.50.0-0.20.6-0.00.20.3-0.3-0.50.5-0.40.2-0.50.50.1-0.2
Total zone transitions, hab. session 22.12.74.11.4-1.7-1.7-1.6-1.4-1.71.71.7-1.72.0-1.31.4-1.61.7-1.61.7-1.81.51.8-1.5
Total locomotion distance, hab. session 25.87.710.82.9-3.0-2.7-3.0-2.9-2.72.23.3-2.73.3-1.41.5-2.22.7-2.72.9-2.93.13.2-2.9
Locomotion velocity, hab. session 25.67.511.02.8-2.9-2.7-2.9-2.8-2.72.33.2-2.73.3-1.51.6-2.32.7-2.72.9-3.03.03.2-2.8
Novel to familiar place preference ratio3.53.65.5-1.81.82.32.11.52.3-2.3-1.42.3-2.31.9-1.91.7-2.01.9-1.71.3-1.7-1.71.5
Novelty place preference3.94.06.0-1.91.72.42.01.62.4-2.4-1.42.4-2.42.0-2.11.9-2.12.1-1.91.4-1.9-1.81.6
Time in novel zone, NPP test3.53.65.5-1.81.62.31.91.52.3-2.3-1.42.2-2.31.9-1.91.8-2.01.9-1.81.4-1.8-1.81.4
Total zone transitions, NPP test0.20.31.0-0.0-0.4-0.8-0.30.3-0.80.60.3-0.70.3-0.70.7-0.50.4-0.30.8-1.00.30.5-0.6
Total locomotion distance, NPP test1.72.44.11.5-1.8-1.4-1.7-1.4-1.41.02.0-1.41.8-0.50.5-1.21.5-1.41.8-1.81.72.0-1.9
Locomotion velocity, NPP test1.92.64.81.8-2.0-1.4-1.8-1.6-1.40.92.2-1.41.9-0.40.5-1.21.6-1.51.7-1.81.82.1-1.9
Intraocular pressure1.62.24.1-1.21.42.01.41.21.9-1.6-0.51.9-0.81.2-1.21.8-1.61.7-1.41.6-0.7-1.41.9
Delta distance traveled before/after self-admin0.10.10.7-0.7-0.80.2-0.20.50.3-0.10.60.2-0.10.2-0.1-0.20.30.10.1-0.5-0.1-0.0-0.5
Delta ambulatory time before/after self-admin0.30.31.2-0.6-1.10.4-0.50.40.5-0.51.00.4-0.10.7-0.60.30.10.4-0.2-0.4-0.10.1-0.7
Parametrial fat weight0.00.10.3-0.10.4-0.40.10.2-0.30.2-0.6-0.2-0.2-0.20.2-0.20.1-0.0-0.0-0.2-0.4-0.00.0
Pavlov. Cond. lever latency0.60.72.3-1.11.50.21.21.30.20.1-1.50.3-1.0-0.40.40.3-0.90.6-0.40.3-0.9-0.91.0
Pavlov. Cond. magazine entry latency2.73.55.61.3-1.9-2.1-2.1-1.0-2.01.81.9-2.12.2-1.71.7-2.22.4-2.01.9-1.81.91.5-1.3
Pavlov. Cond. change in total contacts2.02.14.51.4-1.9-1.2-1.8-1.3-1.20.92.1-1.21.9-0.80.8-1.51.8-1.41.3-1.21.81.3-1.2
Pavlov. Cond. index score0.91.12.40.9-1.4-0.9-1.3-0.9-0.80.71.6-0.91.4-0.50.6-1.01.3-1.01.0-0.91.21.0-0.9
Pavlov. Cond. latency score0.81.02.71.0-1.5-0.8-1.4-1.0-0.60.61.7-0.81.4-0.30.4-0.81.2-0.90.9-0.81.21.0-1.0
Pavlov. Cond. lever contacts0.30.41.00.8-1.0-0.1-0.8-0.8-0.1-0.01.0-0.10.70.4-0.3-0.40.7-0.40.4-0.50.50.8-0.9
Pavlov. Cond. magazine entry number2.43.04.8-1.11.62.01.80.91.9-1.8-1.62.0-2.01.9-1.92.0-2.21.8-1.81.6-1.8-1.20.9
Pavlov. Cond. intertrial magazine entries0.10.20.50.1-0.00.70.2-0.10.6-0.60.20.7-0.20.6-0.60.4-0.30.3-0.30.2-0.0-0.10.0
Pavlov. Cond. lever-magazine prob. diff.1.11.32.61.0-1.5-1.0-1.5-0.8-0.90.91.6-1.01.5-0.60.7-1.21.5-1.11.2-1.01.31.2-1.1
Pavlov. Cond. response bias1.62.03.31.3-1.7-1.3-1.8-1.0-1.31.01.8-1.31.8-0.80.8-1.51.8-1.41.4-1.31.51.4-1.3
Pavlov. Cond. lever latency0.10.10.50.70.4-0.20.0-0.7-0.20.3-0.3-0.20.50.3-0.3-0.10.1-0.30.20.20.10.7-0.4
Pavlov. Cond. magazine entry latency0.20.31.10.20.2-0.60.0-0.1-0.50.80.2-0.60.5-1.11.0-0.40.3-0.40.7-0.40.70.10.2
Pavlov. Cond. change in total contacts0.20.21.5-0.1-0.7-0.2-0.5-0.2-0.30.30.8-0.20.1-0.30.4-0.20.2-0.20.6-1.20.50.4-0.5
Pavlov. Cond. index score0.10.20.8-0.3-0.1-0.30.10.2-0.30.40.4-0.3-0.0-0.90.9-0.30.1-0.20.6-0.70.5-0.30.3
Pavlov. Cond. latency score0.10.10.4-0.2-0.2-0.2-0.00.2-0.20.20.5-0.2-0.0-0.60.6-0.10.1-0.10.4-0.60.5-0.20.2
Pavlov. Cond. lever contacts0.10.10.6-0.8-0.3-0.10.00.6-0.10.00.2-0.1-0.5-0.60.6-0.1-0.00.10.1-0.40.0-0.60.2
Pavlov. Cond. magazine entry number0.91.12.8-0.60.21.10.20.71.1-1.3-0.61.1-0.91.7-1.61.1-0.81.1-1.51.3-1.3-0.50.0
Pavlov. Cond. intertrial magazine entries0.20.31.3-0.40.5-0.70.20.4-0.70.5-1.1-0.7-0.4-0.80.7-0.50.2-0.3-0.10.4-0.6-0.40.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.20.0-0.30.10.1-0.30.30.3-0.3-0.0-0.80.8-0.20.1-0.20.5-0.60.5-0.20.3
Pavlov. Cond. response bias0.20.31.2-0.6-0.0-0.40.10.5-0.40.50.1-0.4-0.2-1.11.1-0.60.3-0.30.6-0.80.4-0.50.3
Time in closed arm before self-admin1.11.33.20.2-0.9-1.4-1.2-0.0-1.41.30.6-1.40.9-1.81.8-1.31.5-1.01.2-1.20.70.2-0.4
Time in closed arm after self-admin0.60.61.60.20.4-0.80.00.2-1.11.2-0.6-1.00.5-1.31.3-1.30.8-0.70.5-0.30.10.2-0.1
Time in open arm before self-admin0.40.41.10.9-0.80.7-0.4-0.90.6-0.80.80.60.31.1-1.10.00.2-0.0-0.30.10.30.5-0.3
Time in open arm after self-admin0.70.82.2-0.3-0.21.00.10.11.0-1.40.21.0-0.81.5-1.51.5-0.90.9-1.00.5-0.5-0.3-0.0
Bone: periosteal estimation0.81.72.71.3-0.9-1.5-1.4-1.2-1.51.60.5-1.51.2-1.41.4-1.61.5-1.51.4-1.10.91.1-0.9
Bone: periosteal perimeter0.40.61.20.6-0.3-0.9-0.9-0.5-1.01.00.2-0.90.4-0.90.9-1.10.9-0.91.0-0.90.40.6-0.7
Bone: post-yield work0.20.31.40.50.30.60.2-0.30.5-0.4-0.30.5-0.40.3-0.30.5-0.30.3-0.71.2-0.4-0.60.6
Progressive ratio test 1 active lever presses0.30.31.30.01.10.71.10.00.8-0.2-0.60.6-0.30.5-0.50.5-0.90.4-0.30.1-0.30.20.1
Progressive ratio test 1 breakpoint0.10.10.70.30.80.30.8-0.20.40.3-0.30.20.10.2-0.10.2-0.60.10.2-0.20.00.5-0.2
Progressive ratio test 1 inactive lever presses0.91.02.0-0.60.11.30.60.81.3-1.4-0.31.1-0.91.4-1.41.2-0.91.1-1.20.6-1.0-0.60.4
Progressive ratio test 2 active lever presses0.20.21.00.5-0.2-0.1-0.1-0.50.00.40.7-0.10.8-0.00.1-0.20.1-0.30.5-0.40.61.0-0.6
Progressive ratio test 2 breakpoint0.20.21.00.6-0.0-0.2-0.1-0.6-0.10.60.6-0.20.8-0.20.2-0.30.2-0.30.6-0.40.61.0-0.6
Progressive ratio test 2 inactive lever presses0.70.82.90.00.11.20.30.21.2-1.10.31.1-0.01.7-1.71.1-0.80.9-0.80.9-0.40.5-0.3
Incentive Sensitization - Responses0.10.10.30.1-0.40.2-0.2-0.20.3-0.10.50.30.30.4-0.30.2-0.00.10.10.10.10.5-0.5
Incentive Sensitization - Breakpoint0.10.10.20.0-0.30.3-0.1-0.10.3-0.30.40.40.10.5-0.40.3-0.20.2-0.10.2-0.00.4-0.4
Sum of active levers in priming session hrs 5-60.40.40.90.2-0.4-0.6-0.3-0.4-0.40.80.4-0.50.5-0.60.7-0.90.7-0.80.9-0.90.60.5-0.5
Progressive ratio0.20.21.31.1-0.8-0.0-0.2-1.10.1-0.20.50.00.6-0.10.1-0.10.2-0.4-0.10.30.3-0.10.4
Food seeking constrained by brief footshock0.10.20.7-0.6-0.20.50.20.80.5-0.50.10.5-0.40.5-0.40.3-0.20.5-0.3-0.3-0.3-0.2-0.1
Seeking ratio, punishment vs. effort0.30.41.9-1.20.40.60.21.40.5-0.4-0.10.6-0.70.8-0.70.5-0.40.8-0.3-0.3-0.4-0.1-0.4
Retroperitoneal fat weight0.31.13.1-1.20.5-1.1-0.30.9-1.51.3-0.7-1.1-0.1-1.81.8-1.00.6-0.41.2-1.5-0.30.2-0.3
Reaction time number correct0.00.00.40.1-0.4-0.0-0.1-0.2-0.0-0.20.1-0.0-0.10.1-0.1-0.00.1-0.1-0.0-0.7-0.20.2-0.3
Reaction time mean minus median0.20.30.70.8-0.8-0.2-0.8-0.9-0.1-0.20.7-0.30.40.5-0.5-0.20.3-0.60.2-0.20.60.4-0.5
Reaction time mean minus median AUC0.30.41.20.8-1.10.1-0.8-0.90.2-0.31.1-0.00.60.8-0.80.00.2-0.30.10.00.70.7-0.6
Reaction time num false alarms1.31.74.1-0.8-0.01.30.40.51.6-1.9-0.11.4-1.12.0-2.01.7-1.31.4-1.81.5-1.1-0.80.3
Reaction time num false alarms AUC1.52.15.4-0.8-0.21.50.30.51.7-2.2-0.01.6-1.22.3-2.31.9-1.31.5-1.91.5-1.2-0.80.3
Reaction time trials correct on left0.00.00.40.1-0.4-0.0-0.1-0.2-0.0-0.20.1-0.0-0.10.1-0.1-0.00.1-0.1-0.0-0.7-0.20.2-0.3
Reaction time trials on left0.00.10.40.2-0.5-0.0-0.2-0.3-0.0-0.20.1-0.1-0.10.2-0.2-0.00.1-0.1-0.0-0.6-0.20.2-0.3
Reaction time mean1.62.23.71.7-1.1-1.5-1.4-1.6-1.51.31.3-1.51.7-1.01.0-1.71.6-1.91.7-1.41.81.3-1.1
Reaction time mean AUC1.31.83.11.6-0.9-1.4-1.2-1.6-1.41.21.1-1.51.5-0.80.8-1.51.3-1.81.5-1.21.71.2-1.0
Median of all reaction times2.02.84.61.7-1.0-1.8-1.4-1.6-1.81.71.3-1.81.8-1.41.4-2.11.8-2.12.0-1.72.01.4-1.1
Reaction time omissions0.50.72.41.5-1.3-0.3-1.1-1.5-0.3-0.30.9-0.30.90.7-0.7-0.30.6-0.8-0.10.30.70.8-0.6
Reaction time false alarm rate0.81.13.1-0.3-0.31.0-0.00.11.2-1.50.31.1-0.61.8-1.81.4-0.91.0-1.41.5-0.5-0.40.2
Reaction time premature initiation rate4.25.68.32.1-1.9-2.9-2.1-1.9-2.72.61.5-2.72.3-2.72.7-2.82.7-2.72.5-2.62.01.6-1.5
Reaction time premature initiations2.63.65.91.6-1.6-2.3-1.7-1.5-2.12.01.1-2.21.7-2.22.2-2.32.3-2.22.0-2.41.41.2-1.2
Std. dev. reaction times0.60.92.11.5-1.2-0.9-1.3-1.4-0.80.41.0-0.91.0-0.10.1-0.80.9-1.20.7-0.51.10.8-0.8
Reaction time trials completed0.00.10.40.2-0.5-0.0-0.2-0.3-0.0-0.20.1-0.1-0.10.2-0.2-0.00.1-0.1-0.0-0.6-0.20.2-0.3
Reaction time trials AUC0.10.10.90.3-0.6-0.3-0.3-0.4-0.30.10.3-0.30.2-0.00.1-0.30.3-0.30.3-1.00.00.4-0.6
Run reversals in cocaine runway, females4.84.69.71.2-0.5-2.4-0.9-1.3-2.63.10.7-2.52.2-2.92.9-2.72.3-2.52.8-2.02.21.5-0.8
Run reversals in cocaine runway, males4.64.56.8-1.81.62.41.81.82.3-2.6-1.32.2-2.01.9-2.02.4-2.22.6-2.52.5-2.3-1.81.7
Latency to leave start box in cocaine runway0.10.10.30.10.2-0.5-0.0-0.2-0.50.4-0.3-0.50.0-0.50.4-0.0-0.2-0.00.1-0.5-0.20.2-0.3
Latency to leave start box in cocaine runway, F0.10.10.40.10.20.20.2-0.40.1-0.3-0.10.2-0.10.2-0.20.5-0.60.4-0.40.0-0.2-0.10.2
Latency to leave start box in cocaine runway, M0.40.41.2-1.00.7-0.70.41.1-0.50.8-1.0-0.6-0.6-0.90.9-0.30.00.00.3-0.4-0.7-0.3-0.1
Std. dev. time between licks in bursts0.50.61.10.2-0.9-0.9-0.7-0.3-0.90.90.7-0.90.7-1.11.1-0.80.9-0.80.7-1.00.60.3-0.4
Total sessions with >9 infusions0.20.20.80.40.70.10.9-0.40.50.6-0.10.20.4-0.30.3-0.1-0.4-0.20.5-0.30.30.50.1
Short access day 1 total inactive lever presses1.61.84.1-0.30.71.70.90.61.8-1.7-0.41.7-0.62.0-2.01.6-1.31.4-1.61.8-0.9-0.50.6
Short access day 10 total inactive lever presses1.82.04.0-1.4-0.01.70.31.41.6-2.0-0.41.6-1.41.7-1.71.7-1.11.6-1.81.0-1.4-1.30.8
Short access day 1 total infusions1.71.93.61.3-0.5-1.3-0.5-1.1-1.21.90.7-1.41.7-1.61.6-1.61.2-1.51.7-1.61.51.4-0.7
Short access day 10 total infusions0.30.31.00.00.80.61.00.20.9-0.3-0.30.6-0.40.8-0.80.4-0.70.3-0.1-0.4-0.30.5-0.2
Short access total infusions1.21.42.81.1-0.1-1.1-0.1-0.9-0.91.70.5-1.11.3-1.41.4-1.40.9-1.41.7-1.61.21.3-0.7
Short access day 1 locomotion0.00.00.20.10.10.20.30.10.30.1-0.00.00.10.2-0.10.0-0.20.20.0-0.4-0.20.4-0.4
Short access day 10 total locomotion0.10.10.6-0.5-0.60.1-0.30.40.5-0.10.80.20.30.3-0.30.2-0.00.30.1-0.20.30.2-0.3
Short access total locomotion0.30.31.1-0.70.40.70.90.91.0-0.3-0.20.7-0.30.6-0.50.5-0.70.7-0.1-0.2-0.4-0.10.1
One hour access (0.3 mA shock)1.31.53.41.4-1.1-0.9-1.0-1.2-0.61.11.6-0.81.7-0.70.7-1.01.1-1.31.6-1.11.61.9-1.2
Compulsive drug intake0.20.20.5-0.3-0.7-0.5-0.70.4-0.50.40.5-0.40.3-0.60.6-0.40.6-0.40.5-0.20.30.1-0.2
One hour access (shock baseline)0.10.10.70.7-0.20.10.1-0.60.30.10.50.10.60.2-0.20.0-0.0-0.20.2-0.10.30.8-0.3
Social response proportion1.92.04.60.7-0.5-1.9-0.5-0.8-1.92.10.2-1.90.9-1.81.9-1.51.0-1.31.7-1.90.71.2-1.5
Social responses3.24.26.32.0-2.0-2.4-1.8-1.9-2.52.01.4-2.51.7-1.61.7-2.11.9-2.12.1-2.31.52.1-2.4
Social time1.41.93.21.8-1.5-1.3-1.7-1.7-1.21.01.3-1.21.4-0.10.2-1.31.6-1.41.2-0.91.41.8-1.8
Soleus weight0.30.92.5-0.10.9-1.10.10.4-1.21.6-0.9-1.10.5-1.51.5-1.30.9-0.81.1-0.70.20.3-0.1
Bone: stiffness3.35.28.92.1-1.9-2.8-1.8-2.3-2.72.41.2-2.81.6-1.92.0-3.02.7-3.02.5-2.21.91.8-2.1
Tibialis anterior weight2.58.617.44.2-3.1-3.0-3.6-3.9-3.02.42.6-3.02.9-1.01.0-2.73.4-3.32.3-2.32.93.0-3.1
Time to tail flick, vehicle, before self-admin0.60.72.1-0.21.3-0.90.70.3-0.71.2-1.0-0.70.1-1.51.4-1.10.2-0.40.7-0.40.2-0.10.5
Time to tail flick, vehicle, after self-admin0.30.31.51.1-0.3-0.1-0.4-1.2-0.40.50.7-0.30.7-0.10.2-0.20.3-0.50.3-0.31.00.4-0.4
Time to tail flick, test, before self-admin0.20.20.7-0.20.70.00.80.30.20.2-0.80.0-0.4-0.40.40.2-0.40.2-0.20.5-0.6-0.50.5
Time to tail flick, test, after self-admin1.01.12.60.30.1-1.2-0.4-0.8-1.61.4-0.0-1.30.9-1.61.6-1.51.1-1.21.0-0.70.80.5-0.2
Delta time to tail flick, vehicle, before/after SA0.50.51.90.3-0.51.1-0.2-0.50.9-0.90.80.9-0.01.4-1.31.1-0.50.6-0.70.20.10.0-0.3
Delta time to tail flick, test, before/after SA0.30.30.7-0.1-0.2-0.4-0.6-0.3-0.70.40.4-0.50.5-0.60.6-0.90.8-0.50.5-0.60.50.2-0.2
Tibia length1.44.016.2-1.71.7-2.01.21.7-2.03.0-1.9-2.0-0.3-4.04.0-1.60.4-0.82.0-2.1-0.4-0.50.5
Ambulatory time before self-admin0.40.41.6-0.11.0-0.40.50.1-0.80.9-0.7-0.80.3-1.31.2-0.3-0.2-0.10.20.80.0-0.30.7
Ambulatory time after self-admin0.30.41.4-1.20.80.20.81.00.10.5-0.50.1-0.2-0.80.80.0-0.40.50.10.3-0.5-0.50.7
Bone: tissue strength1.00.91.81.2-1.4-1.1-1.1-1.3-1.10.60.9-1.10.5-0.50.5-1.01.0-1.30.8-0.60.90.6-1.0
Total heroin consumption0.30.40.9-0.60.00.60.30.20.5-0.9-0.40.5-0.70.7-0.70.7-0.50.6-0.70.9-0.9-0.40.3
Bone: trabecular number0.20.31.00.7-0.0-0.4-0.2-1.0-0.60.6-0.2-0.50.5-0.40.4-0.90.7-0.90.5-0.40.50.2-0.0
Bone: trabecular spacing0.71.02.2-0.60.51.10.60.71.2-1.2-0.31.1-0.91.0-1.01.5-1.11.3-1.21.2-0.9-0.70.7
Bone: trabecular thickness0.40.51.4-0.90.3-0.80.10.7-0.81.1-0.6-0.8-0.1-1.21.2-0.80.4-0.40.7-0.8-0.2-0.1-0.1
Bone: trabecular tissue density0.30.40.80.2-0.6-0.7-0.2-0.3-0.70.60.9-0.70.6-0.80.8-0.60.4-0.50.8-0.90.90.4-0.4
Water consumed over 24 hours0.60.71.9-1.40.40.90.71.20.9-0.6-0.40.9-0.80.5-0.41.1-1.11.2-0.7-0.1-0.8-0.80.5
Number of responses in last shaping day0.60.61.40.00.81.10.90.21.2-0.8-0.41.0-0.30.9-0.90.9-1.00.8-0.91.0-0.5-0.10.4