Hub : Genes

Cerk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Cerk 0.19 0.13 1.0e-03 0.15 -0.01 0.12 -0.01 2.3e-04 5.8e-01 8.8e-04 5.0e-01
2 Liver intron excision ratio chr7_119112248_119115176 0.03 0.02 8.4e-04 0 0.01 0.01 0.01 1.2e-01 9.8e-03 4.7e-02 6.9e-02
3 Liver intron excision ratio chr7_119115328_119117149 0.03 0.02 1.4e-03 0.01 0.01 0.01 0.01 5.0e-02 7.1e-03 3.0e-02 3.2e-02
4 Adipose gene expression Cerk 0.2 0.1 0.0e+00 0.17 0.18 0.18 0.18 5.0e-19 1.2e-19 1.3e-19 6.1e-20
5 IC intron excision ratio chr7_119117223_119120822 0.07 0.05 3.0e-03 0.06 0.04 0.03 0.05 2.1e-03 1.2e-02 2.9e-02 2.8e-03
6 IC intron excision ratio chr7_119120967_119122323 0.08 0.06 1.2e-03 0.08 0.05 0.05 0.07 2.4e-04 3.2e-03 3.7e-03 8.9e-04
7 Brain gene expression Cerk 0.03 0.03 7.2e-03 0.02 0.01 -0 0 5.2e-03 5.0e-02 4.2e-01 3.6e-01
8 Brain mRNA stability Cerk 0.04 0.03 2.3e-03 0.04 0.03 0.03 0.03 7.7e-05 3.7e-04 6.9e-04 5.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.50.91.1-0.8-1.01.1-1.00.9-0.9-1.0-0.9
Area under the delay curve3.64.14.7-2.2-2.22.1-2.12.2-2.2-1.8-1.5
BMI with tail2.37.810.43.12.8-2.72.8-2.92.93.21.7
BMI without tail0.61.93.01.21.2-1.21.2-1.71.71.31.4
Body weight2.19.29.92.93.1-3.13.0-3.03.03.13.1
Weight adjusted by age1.52.33.41.51.3-1.21.2-1.81.81.21.8
Bone surface0.20.30.6-0.7-0.70.7-0.70.4-0.4-0.3-0.4
Bone volume0.40.60.9-0.9-0.90.9-0.90.7-0.7-0.6-0.5
Breakpoint value in progressive ratio session0.30.41.60.80.4-0.20.4-0.30.30.4-1.3
Number of licking bursts0.10.20.3-0.6-0.40.3-0.40.4-0.4-0.60.5
Context. condit. distance diff. score0.91.11.81.21.2-1.11.4-0.80.81.30.4
Locomotion velocity, session 11.41.52.90.91.2-1.31.3-1.21.20.91.7
Locomotion distance, session 10.20.30.8-0.9-0.50.4-0.40.5-0.5-0.50.2
Locomotion velocity, session 23.74.35.62.02.3-2.42.1-1.91.91.82.3
Locomotion distance, session 20.10.20.3-0.3-0.50.5-0.50.3-0.3-0.2-0.6
Locomotion velocity, session 32.02.35.61.11.6-1.81.6-0.90.91.22.4
Locomotion distance, session 30.10.20.9-0.10.2-0.40.10.3-0.3-0.00.9
Stereotopy head waving bouts, day 30.50.61.40.40.7-0.70.6-0.70.71.20.9
Stereotopy head waving duration, day 31.72.04.30.91.2-1.21.3-1.51.52.11.3
Locomotion velocity, session 71.11.22.80.71.1-1.21.1-0.70.71.41.7
Locomotion distance, session 70.30.30.80.60.7-0.80.60.1-0.10.20.9
Stereotopy head waving bouts, day 71.11.31.80.81.1-1.21.2-1.01.01.31.4
Stereotopy head waving duration, day 70.40.50.80.40.6-0.70.7-0.50.50.90.9
Locomotion velocity, session 85.66.77.92.82.7-2.72.8-2.62.62.71.6
Locomotion distance, session 80.50.71.30.91.0-1.01.1-0.60.60.70.6
Degree of sensitization distance0.90.91.81.31.1-0.91.0-1.01.00.70.2
Degree of sensitization stereotypy0.70.70.90.70.9-0.90.9-0.80.81.00.8
Conditioned locomotion0.10.10.30.30.3-0.30.3-0.20.20.50.3
Cocaine response after cond. corrected0.30.30.60.70.7-0.80.8-0.30.30.20.6
Cocaine response after cond. not corrected0.20.20.40.30.5-0.60.60.3-0.3-0.00.6
Cocaine response before conditioning0.40.50.9-0.8-0.60.5-0.60.9-0.9-0.6-0.2
Saline control response0.20.20.60.80.5-0.40.5-0.30.3-0.3-0.1
Bone: connectivity density0.20.40.5-0.6-0.70.7-0.70.6-0.6-0.5-0.1
Bone: cortical apparent density1.42.02.3-1.5-1.51.5-1.51.3-1.3-1.4-1.1
Bone: cortical area2.23.44.91.91.8-1.71.8-2.22.21.71.0
Bone: cortical porosity1.41.52.61.61.3-1.21.2-1.61.60.60.3
Bone: cortical porosity1.71.83.01.61.3-1.21.2-1.71.70.70.6
Bone: cortical thickness0.10.20.50.70.3-0.20.2-0.70.70.2-0.3
Bone: cortical thickness2.02.44.31.81.4-1.21.4-2.12.11.40.2
Bone: cortical tissue density1.11.51.8-1.3-1.31.3-1.31.1-1.1-1.2-1.0
Condit. Reinf. active minus inactive responses0.30.30.9-0.5-0.50.5-0.60.1-0.1-0.9-0.6
Condit. Reinf. active-inactive response ratio1.21.31.8-1.2-1.21.2-1.30.8-0.8-1.3-1.2
Condit. Reinf. active responses0.60.81.7-1.0-0.80.7-0.90.8-0.8-1.3-0.4
Condit. Reinf. inactive responses0.20.20.6-0.4-0.20.0-0.20.8-0.8-0.60.3
Incentive salience index mean0.20.30.50.20.5-0.60.3-0.70.7-0.30.7
Condit. Reinf. lever presses1.72.45.01.11.6-1.71.4-1.61.60.82.2
Condit. Reinf. active minus inactive responses0.60.81.61.00.8-0.70.5-1.31.30.7-0.2
Condit. Reinf. active-inactive response ratio0.10.10.40.30.2-0.20.0-0.60.60.3-0.5
Condit. Reinf. active responses1.82.54.11.71.6-1.41.3-2.02.01.60.6
Condit. Reinf. inactive responses2.83.74.71.91.9-1.81.9-2.02.02.21.5
Condit. Reinf. lever presses0.71.02.60.71.0-0.90.9-1.01.01.60.5
Condit. Reinf. lever reinforcers received1.21.72.81.41.3-1.21.1-1.71.71.30.3
Conditioned reinforcement - actives0.10.20.40.70.5-0.50.5-0.00.0-0.4-0.1
Conditioned reinforcement - inactives0.40.51.61.30.9-0.81.0-0.40.4-0.0-0.0
Conditioned locomotion1.62.13.21.51.7-1.81.8-1.01.00.91.5
Patch foraging indifference point 0 sec0.00.00.1-0.0-0.00.00.0-0.20.2-0.20.3
Patch foraging indifference point AUC0.30.51.1-1.1-0.70.7-0.70.7-0.7-0.6-0.2
Delay disc. indifference point, 0s delay0.10.10.20.50.2-0.20.10.2-0.20.10.4
Delay disc. indifference point, 16s delay4.24.75.4-2.1-2.32.3-2.32.3-2.3-1.9-1.9
Delay disc. indifference point, 2s delay0.70.81.1-0.9-0.91.0-1.10.8-0.8-0.9-0.5
Delay disc. indifference point, 24s delay0.10.10.2-0.1-0.10.2-0.1-0.30.3-0.1-0.5
Delay disc. indifference point, 4s delay6.46.78.3-2.9-2.92.9-2.92.7-2.7-1.7-1.8
Delay disc. indifference point, 8s delay3.44.04.7-2.2-2.22.1-2.02.1-2.1-1.6-1.5
Indifference point function ln k2.54.45.62.42.3-2.32.2-2.12.11.71.7
Indifference point function log k2.54.45.62.42.3-2.32.2-2.12.11.71.7
Patch foraging total patch changes 0 sec0.00.10.2-0.4-0.40.3-0.30.2-0.2-0.40.1
Patch foraging total patch changes 12 sec0.00.00.2-0.4-0.10.1-0.1-0.00.0-0.00.4
Patch foraging total patch changes 18 sec0.30.40.8-0.9-0.70.7-0.70.5-0.5-0.90.1
Patch foraging total patch changes 24 sec0.10.10.3-0.5-0.20.1-0.00.5-0.5-0.10.5
Patch foraging total patch changes 6 sec0.60.81.6-1.3-1.11.1-1.00.8-0.8-0.7-0.3
Patch foraging time to switch 0 sec0.20.50.8-0.6-0.80.9-0.80.5-0.5-0.3-0.8
Patch foraging water rate 0 sec0.40.81.30.60.8-0.80.8-1.11.10.90.6
Patch foraging water rate 12 sec0.61.32.71.11.1-1.21.2-1.11.10.21.7
Patch foraging water rate 18 sec0.30.41.00.10.5-0.50.5-1.01.00.00.7
Patch foraging water rate 24 sec0.70.91.51.21.0-1.01.0-1.11.10.60.3
Patch foraging water rate 6 sec0.10.20.8-0.20.1-0.20.2-0.20.2-0.70.9
Seeking ratio, delayed vs. immediate footshock1.41.82.2-1.1-1.41.4-1.51.4-1.4-1.2-1.3
Distance traveled before self-admin0.10.10.40.20.4-0.50.4-0.00.0-0.30.6
Distance traveled after self-admin0.50.70.90.90.9-0.80.9-1.01.00.40.3
Extensor digitorum longus weight0.41.72.11.41.4-1.41.5-1.11.11.41.2
Bone: elastic displacement0.60.71.40.70.8-0.90.9-0.80.80.11.2
Bone: elastic work3.95.17.12.42.3-2.22.3-2.72.72.01.5
Bone: endosteal estimation2.24.85.82.02.3-2.32.3-2.12.12.42.0
Bone: endosteal perimeter3.77.99.22.72.9-2.92.9-3.03.02.62.5
Epididymis fat weight0.62.14.12.01.6-1.51.5-1.41.41.00.8
Delta time in closed arm before/after self-admin0.00.00.10.3-0.00.1-0.1-0.30.3-0.1-0.0
Delta time in open arm before/after self-admin0.40.42.7-0.30.2-0.40.20.2-0.2-0.11.6
Diff in mean of infusions in LGA sessions1.11.32.41.61.2-1.11.2-1.31.30.7-0.7
Delay discount exponential model param3.84.24.92.22.2-2.12.2-2.12.11.81.5
Extinction: sum of active levers before priming0.20.21.10.60.2-0.10.4-0.10.10.2-1.0
Active lever presses in extinction session 61.21.22.21.41.2-1.11.2-0.90.91.50.1
Bone: final force0.81.32.21.41.0-0.91.1-1.31.31.5-0.1
Bone: final moment1.11.72.81.51.1-0.91.2-1.61.61.7-0.2
Food consumed during 24 hour testing period4.76.59.62.32.6-2.52.4-3.13.12.41.8
Glucose0.20.20.60.50.3-0.30.2-0.80.8-0.5-0.2
Heart weight1.52.35.21.71.4-1.31.3-1.41.42.30.8
Delay discount hyperbolic model param4.14.55.42.32.3-2.22.2-2.22.21.91.5
Intermittent access intake day 1-15 change1.12.23.71.91.6-1.51.6-1.71.70.40.6
Intermittent access intake escalation0.51.01.71.31.1-1.11.0-1.11.1-0.10.5
Intermittent access intake escalation 20.70.81.61.10.7-0.60.7-1.31.3-0.6-0.1
Intermitt. access day 1 inactive lever presses0.10.20.60.80.4-0.20.3-0.70.70.3-0.2
Intermitt. access day 15 inactive lever presses1.22.53.41.81.7-1.61.7-1.91.91.00.6
Intermitt. access escalation Index0.10.20.4-0.3-0.40.4-0.30.4-0.4-0.6-0.6
Intermittent access day 1 total infusions1.93.05.01.92.0-2.22.1-0.80.81.02.2
Intermittent access day 15 total infusions2.23.35.42.32.2-2.32.2-1.11.10.41.9
Intermittent access terminal intake (last 3 days)4.45.89.33.12.8-2.92.8-1.91.90.82.2
Intermittent access total infusions3.74.37.52.72.5-2.52.5-1.41.40.72.0
Intermittent access day 1 locomotion0.60.81.60.91.0-1.21.00.1-0.1-0.11.3
Intermittent access day 15 total locomotion2.34.26.72.22.5-2.62.5-1.31.31.12.3
Intermittent access total locomotion3.13.75.72.32.3-2.42.3-1.31.30.81.9
Intermittent access standard deviation1.63.45.72.42.0-1.92.0-1.91.91.01.0
Left kidney weight12.357.266.17.77.8-7.77.8-7.57.58.16.1
Right kidney weight12.054.765.97.87.6-7.47.5-7.47.48.15.5
Cocaine induced anxiety0.30.50.80.90.6-0.40.5-0.80.80.9-0.2
Post-drug Anxiety0.40.42.4-0.1-0.50.6-0.50.2-0.2-0.3-1.5
Baseline Anxiety0.50.61.2-0.8-0.60.5-0.51.1-1.1-1.0-0.4
Tail length0.20.72.3-0.9-0.40.1-0.50.1-0.1-1.51.3
Length with tail0.62.46.11.11.6-1.81.4-1.41.40.72.5
Length without tail1.65.26.92.62.5-2.52.4-2.12.12.31.6
Times rat made contact with spout0.60.61.20.50.8-0.90.7-0.60.61.11.1
Lifetime Intake3.44.16.72.62.4-2.52.4-1.41.40.72.0
Liver weight, left2.13.54.61.92.1-2.12.1-1.41.41.62.0
Liver weight, right1.11.95.20.91.5-1.71.4-0.70.70.92.3
Locomotor activity3.96.18.92.22.5-2.62.4-2.42.42.23.0
Locomotor testing distance0.40.71.70.60.8-0.80.9-0.70.70.61.3
Locomotor testing rearing0.71.52.00.91.2-1.31.3-1.11.11.31.4
Locomotion in novel chamber0.60.82.6-1.5-0.30.1-0.40.8-0.8-0.31.6
Locomotion in novel chamber post-restriction0.20.30.7-0.8-0.50.5-0.30.7-0.7-0.0-0.5
Fecal boli incidents, locomotor time 10.10.10.40.30.4-0.50.40.0-0.00.60.3
Change in fecal boli incidents, locomotor task0.10.10.4-0.6-0.20.2-0.2-0.40.4-0.10.3
Time >=10cm from walls, locomotor time 10.20.21.4-0.00.0-0.00.1-0.20.21.2-0.1
Bouts of movement, locomotor time 10.40.40.91.00.8-0.70.8-0.40.40.50.1
Total resting periods, locomotor time 10.20.20.40.60.4-0.30.5-0.20.20.5-0.3
Rest time, locomotor task time 10.60.71.70.50.8-0.81.0-0.40.41.31.1
Distance moved, locomotor task time 10.00.00.0-0.20.0-0.0-0.1-0.00.0-0.1-0.1
Vertical activity count, locomotor time 10.10.30.9-0.5-0.50.5-0.7-0.10.1-0.3-0.9
Time >=10cm from walls, locomotor time 20.30.40.80.70.4-0.30.4-0.90.90.8-0.3
Bouts of movement, locomotor time 20.71.11.9-0.8-1.11.2-1.00.8-0.8-1.0-1.4
Total resting periods, locomotor time 20.71.22.1-0.8-1.11.2-1.00.9-0.9-1.1-1.4
Rest time, locomotor task time 21.82.34.0-1.7-1.41.1-1.42.0-2.0-1.50.2
Distance moved, locomotor task time 22.42.83.51.91.8-1.71.8-1.91.91.60.7
Vertical activity count, locomotor time 22.12.84.81.81.6-1.51.5-2.22.21.60.4
Light reinforcement 10.61.53.70.51.1-1.21.0-0.90.91.61.9
Light reinforcement 23.75.76.82.52.6-2.62.5-2.32.32.32.0
Bone: marrow area2.14.75.62.02.3-2.32.3-2.02.02.41.9
Bone: maximum diameter7.013.116.03.73.7-3.73.7-4.04.03.42.6
Bone: maximum force1.01.83.11.51.2-0.91.2-1.61.61.8-0.2
Bone: maximum moment1.32.33.81.71.3-1.01.4-1.91.92.0-0.2
Mean time between licks in bursts0.51.22.2-1.5-1.21.1-1.11.2-1.2-0.9-0.1
Mean num. licks in bursts0.81.31.71.31.2-1.11.2-1.21.21.20.4
Cd content in liver0.10.10.3-0.10.1-0.00.0-0.40.40.60.0
Co content in liver0.10.10.5-0.30.0-0.1-0.1-0.20.20.10.7
Cu content in liver8.810.412.4-3.1-3.33.3-3.23.5-3.5-2.7-3.1
Fe content in liver0.20.30.60.70.4-0.30.5-0.60.60.5-0.4
K content in liver0.00.00.30.10.0-0.00.00.1-0.1-0.2-0.5
Mg content in liver0.20.21.2-0.1-0.30.4-0.20.4-0.4-0.3-1.1
Mn content in liver1.11.31.91.11.3-1.41.2-1.01.00.51.3
Na content in liver2.72.95.2-1.5-1.71.7-1.91.5-1.5-1.4-2.3
Rb content in liver0.60.73.3-0.4-0.70.9-0.60.3-0.3-0.1-1.8
Se content in liver0.10.10.2-0.1-0.0-0.00.20.5-0.5-0.3-0.2
Sr content in liver1.10.92.8-1.7-0.90.8-0.81.0-1.0-0.60.4
Zn content in liver0.10.10.4-0.6-0.30.2-0.10.5-0.50.10.0
Bone: minimum diameter2.13.84.51.92.1-2.12.0-2.02.01.61.8
Time in familiar zone, hab. session 11.31.32.31.11.1-1.11.1-0.90.91.51.1
Time in novel zone, hab. session 10.30.30.6-0.5-0.50.5-0.5-0.20.2-0.6-0.8
Total zone transitions, hab. session 12.23.13.7-1.8-1.81.8-1.81.7-1.7-1.6-1.9
Total locomotion distance, hab. session 10.10.10.3-0.5-0.20.2-0.20.4-0.4-0.40.0
Locomotion velocity, hab. session 10.10.10.3-0.5-0.20.1-0.20.4-0.4-0.40.2
Time in familiar zone, hab. session 20.10.10.40.30.5-0.60.5-0.20.20.20.3
Time in novel zone, hab. session 20.50.51.0-0.7-0.91.0-0.90.4-0.4-0.8-0.5
Total zone transitions, hab. session 20.20.20.40.40.3-0.20.4-0.50.50.5-0.6
Total locomotion distance, hab. session 20.10.10.10.20.3-0.30.3-0.40.40.1-0.3
Locomotion velocity, hab. session 20.00.10.10.10.2-0.20.3-0.30.30.0-0.3
Novel to familiar place preference ratio0.40.41.0-1.0-0.80.8-0.80.4-0.4-0.3-0.1
Novelty place preference0.20.20.6-0.8-0.50.5-0.50.1-0.1-0.00.2
Time in novel zone, NPP test0.20.30.8-0.9-0.60.6-0.60.1-0.10.00.2
Total zone transitions, NPP test1.11.62.6-1.0-1.21.3-1.01.6-1.6-1.2-1.1
Total locomotion distance, NPP test0.20.30.8-0.4-0.40.4-0.30.9-0.9-0.6-0.2
Locomotion velocity, NPP test0.30.41.2-0.5-0.40.4-0.31.1-1.1-0.6-0.2
Intraocular pressure0.71.03.20.81.1-1.21.0-0.20.20.81.8
Delta distance traveled before/after self-admin0.70.71.10.80.8-0.80.7-0.90.91.00.7
Delta ambulatory time before/after self-admin0.40.50.80.70.7-0.70.6-0.60.60.90.5
Parametrial fat weight0.51.12.4-1.1-0.80.7-0.91.5-1.5-0.90.6
Pavlov. Cond. lever latency1.72.13.8-1.3-1.41.5-1.41.5-1.5-0.4-2.0
Pavlov. Cond. magazine entry latency0.10.10.40.20.0-0.0-0.1-0.50.5-0.60.1
Pavlov. Cond. change in total contacts0.50.51.40.60.5-0.50.4-1.21.2-0.00.3
Pavlov. Cond. index score0.40.50.90.70.6-0.60.6-0.90.9-0.20.8
Pavlov. Cond. latency score0.60.81.20.90.8-0.80.8-1.11.10.10.9
Pavlov. Cond. lever contacts1.72.03.71.31.4-1.51.4-1.51.50.31.9
Pavlov. Cond. magazine entry number0.10.10.4-0.2-0.10.10.00.3-0.30.6-0.1
Pavlov. Cond. intertrial magazine entries1.01.21.9-1.0-1.01.0-1.01.1-1.1-1.4-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.60.50.5-0.50.4-0.80.8-0.30.8
Pavlov. Cond. response bias0.70.91.31.01.0-1.00.8-1.01.0-0.11.1
Pavlov. Cond. lever latency0.30.51.0-0.6-0.60.6-0.50.8-0.8-1.0-0.3
Pavlov. Cond. magazine entry latency1.41.75.8-0.7-1.21.4-1.21.0-1.0-0.6-2.4
Pavlov. Cond. change in total contacts0.20.41.10.20.00.2-0.2-0.80.80.5-1.1
Pavlov. Cond. index score0.10.21.1-0.1-0.30.4-0.3-0.00.00.2-1.1
Pavlov. Cond. latency score0.10.21.00.0-0.20.3-0.3-0.10.10.4-1.0
Pavlov. Cond. lever contacts0.20.30.60.60.5-0.40.4-0.70.70.70.1
Pavlov. Cond. magazine entry number0.50.62.40.50.7-0.90.8-0.40.40.21.5
Pavlov. Cond. intertrial magazine entries0.50.81.41.20.9-0.81.0-1.01.00.70.2
Pavlov. Cond. lever-magazine prob. diff.0.20.21.1-0.2-0.40.5-0.40.1-0.10.2-1.1
Pavlov. Cond. response bias0.10.10.5-0.0-0.10.2-0.2-0.20.20.2-0.7
Time in closed arm before self-admin0.91.23.6-0.7-1.01.0-0.91.0-1.0-1.9-1.0
Time in closed arm after self-admin0.20.21.0-0.2-0.40.4-0.40.4-0.4-1.00.1
Time in open arm before self-admin0.10.20.4-0.4-0.20.1-0.20.6-0.60.5-0.0
Time in open arm after self-admin0.10.10.3-0.20.0-0.1-0.00.5-0.50.40.3
Bone: periosteal estimation3.06.47.42.52.6-2.52.6-2.72.72.61.9
Bone: periosteal perimeter5.59.511.32.93.2-3.23.1-3.43.42.72.6
Bone: post-yield work0.71.01.7-1.1-1.21.3-1.30.6-0.60.1-1.3
Progressive ratio test 1 active lever presses0.70.81.71.01.1-1.21.10.1-0.10.11.3
Progressive ratio test 1 breakpoint0.60.71.60.90.9-1.11.00.2-0.2-0.01.3
Progressive ratio test 1 inactive lever presses0.81.22.51.21.2-1.31.3-0.30.30.81.6
Progressive ratio test 2 active lever presses0.50.61.91.41.0-0.91.0-0.20.20.2-0.2
Progressive ratio test 2 breakpoint0.50.51.71.30.9-0.91.0-0.10.10.1-0.0
Progressive ratio test 2 inactive lever presses0.50.82.51.61.1-1.11.2-0.20.20.10.3
Incentive Sensitization - Responses0.30.41.21.10.7-0.50.7-0.40.40.2-0.7
Incentive Sensitization - Breakpoint0.40.51.31.20.8-0.70.8-0.50.50.3-0.5
Sum of active levers in priming session hrs 5-60.20.11.10.0-0.10.2-0.10.0-0.00.1-1.1
Progressive ratio0.20.30.5-0.7-0.50.5-0.70.5-0.5-0.7-0.3
Food seeking constrained by brief footshock0.70.81.41.20.9-0.80.8-1.01.01.1-0.1
Seeking ratio, punishment vs. effort0.91.32.51.61.0-0.81.0-1.21.21.4-0.6
Retroperitoneal fat weight2.711.717.14.13.7-3.63.6-3.03.03.32.9
Reaction time number correct0.20.30.6-0.8-0.60.5-0.70.5-0.5-0.6-0.2
Reaction time mean minus median0.20.40.9-0.6-0.50.5-0.50.7-0.7-0.9-0.4
Reaction time mean minus median AUC0.10.20.7-0.4-0.30.2-0.20.9-0.9-0.20.1
Reaction time num false alarms0.10.20.80.20.4-0.60.4-0.10.1-0.30.9
Reaction time num false alarms AUC0.20.31.10.20.6-0.70.6-0.20.2-0.31.0
Reaction time trials correct on left0.20.30.6-0.8-0.60.5-0.70.5-0.5-0.6-0.2
Reaction time trials on left0.20.40.6-0.8-0.60.6-0.80.6-0.6-0.6-0.2
Reaction time mean2.13.34.2-1.5-1.92.0-1.81.8-1.8-1.8-2.0
Reaction time mean AUC2.43.84.3-1.7-2.02.1-1.92.0-2.0-1.9-2.1
Median of all reaction times2.73.85.5-1.6-2.02.2-1.91.8-1.8-1.8-2.3
Reaction time omissions1.01.52.1-1.3-1.41.4-1.51.2-1.2-1.0-1.0
Reaction time false alarm rate0.40.61.10.70.9-1.00.9-0.60.60.01.0
Reaction time premature initiation rate0.50.61.50.90.4-0.10.3-1.11.10.5-1.2
Reaction time premature initiations0.20.31.80.3-0.10.3-0.2-0.60.60.0-1.3
Std. dev. reaction times0.71.32.1-1.0-1.21.1-1.11.3-1.3-1.5-0.7
Reaction time trials completed0.20.40.6-0.8-0.60.6-0.80.6-0.6-0.6-0.2
Reaction time trials AUC0.10.10.3-0.5-0.40.3-0.50.3-0.3-0.3-0.1
Run reversals in cocaine runway, females0.30.31.0-1.0-0.50.4-0.50.0-0.0-0.50.8
Run reversals in cocaine runway, males1.11.14.00.41.0-1.11.0-0.60.60.72.0
Latency to leave start box in cocaine runway1.71.92.71.21.4-1.41.6-1.41.41.41.1
Latency to leave start box in cocaine runway, F1.51.72.31.31.4-1.41.5-1.31.31.40.9
Latency to leave start box in cocaine runway, M0.40.40.60.40.6-0.60.7-0.80.80.50.6
Std. dev. time between licks in bursts0.10.10.3-0.3-0.40.5-0.4-0.10.1-0.1-0.1
Total sessions with >9 infusions2.73.34.31.82.0-2.12.0-1.41.41.52.1
Short access day 1 total inactive lever presses3.84.97.32.72.4-2.32.4-2.12.11.91.6
Short access day 10 total inactive lever presses0.51.11.51.21.0-1.01.1-1.21.20.81.0
Short access day 1 total infusions1.52.03.21.51.6-1.61.5-1.31.30.81.8
Short access day 10 total infusions2.93.75.32.22.2-2.32.2-1.41.41.02.2
Short access total infusions3.34.26.22.52.4-2.42.4-1.71.71.31.8
Short access day 1 locomotion0.10.10.20.50.5-0.50.5-0.30.30.00.3
Short access day 10 total locomotion0.40.84.5-0.20.6-0.80.70.2-0.20.12.1
Short access total locomotion0.70.91.80.91.1-1.21.1-0.40.40.41.3
One hour access (0.3 mA shock)1.72.04.32.11.7-1.71.7-0.80.80.80.9
Compulsive drug intake0.10.20.6-0.2-0.30.4-0.3-0.20.20.2-0.8
One hour access (shock baseline)1.72.64.92.22.0-2.12.0-0.90.90.61.5
Social response proportion1.92.13.01.51.4-1.41.3-1.71.71.51.1
Social responses2.02.64.21.11.5-1.61.5-1.71.71.52.1
Social time0.20.21.3-0.2-0.0-0.10.00.3-0.3-0.71.1
Soleus weight0.30.91.31.21.0-0.91.0-1.11.10.90.2
Bone: stiffness0.50.84.60.0-0.50.8-0.5-0.10.10.5-2.2
Tibialis anterior weight0.20.81.0-0.9-0.90.9-0.81.0-1.0-0.2-1.0
Time to tail flick, vehicle, before self-admin0.20.20.4-0.5-0.30.3-0.40.7-0.7-0.00.1
Time to tail flick, vehicle, after self-admin0.10.10.40.10.3-0.30.3-0.10.1-0.30.6
Time to tail flick, test, before self-admin1.92.03.01.21.3-1.41.4-1.51.51.21.7
Time to tail flick, test, after self-admin0.30.30.80.50.3-0.10.5-0.90.9-0.0-0.6
Delta time to tail flick, vehicle, before/after SA0.90.91.60.90.9-0.80.8-1.31.30.90.4
Delta time to tail flick, test, before/after SA1.71.84.6-1.0-1.31.4-1.20.9-0.9-1.5-2.1
Tibia length0.20.60.91.00.9-0.91.0-0.70.70.20.2
Ambulatory time before self-admin0.10.20.80.00.3-0.40.30.2-0.2-0.40.9
Ambulatory time after self-admin0.10.10.20.30.2-0.20.2-0.30.3-0.40.1
Bone: tissue strength0.40.41.4-0.2-0.60.7-0.50.3-0.3-0.3-1.2
Total heroin consumption0.60.71.51.00.8-0.60.8-0.40.41.2-1.1
Bone: trabecular number0.50.91.3-0.9-1.00.9-1.01.0-1.0-1.1-0.3
Bone: trabecular spacing2.83.76.41.71.9-1.91.8-2.02.02.51.3
Bone: trabecular thickness0.10.20.9-0.2-0.30.3-0.20.3-0.3-1.0-0.1
Bone: trabecular tissue density1.72.54.1-1.4-1.51.6-1.51.6-1.6-1.3-2.0
Water consumed over 24 hours1.41.93.21.11.3-1.31.2-1.81.81.31.0
Number of responses in last shaping day0.20.20.4-0.5-0.50.6-0.60.3-0.3-0.2-0.2