Hub : Genes

Cenpm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Cenpm 0.08 0.04 1.0e-10 0.11 0.11 0.11 0.1 2.0e-10 2.9e-10 1.3e-10 8.5e-10
2 LHb gene expression Cenpm 0.13 0.08 6.8e-03 0.03 0.05 0.04 0.03 6.5e-02 2.3e-02 4.7e-02 6.4e-02
3 NAcc isoform ratio NM_001130504.1 0.04 0.02 5.1e-05 0.04 0.04 0.04 0.04 2.8e-05 1.9e-05 3.1e-05 1.5e-05
4 pVTA isoform ratio NM_001130504.1 0.13 0.09 7.0e-05 0.13 0.08 0.12 0.13 4.2e-06 1.8e-04 7.2e-06 2.7e-06
5 BLA gene expression Cenpm 0.09 0.05 2.3e-03 0.03 0.04 0.04 0.03 6.2e-03 3.1e-03 4.7e-03 8.0e-03
6 pVTA intron excision ratio chr7_113753971_113758674 0.14 0.08 2.7e-06 0.1 0.12 0.11 0.1 3.7e-05 8.3e-06 2.5e-05 3.2e-05
7 pVTA isoform ratio XM_008765720.3 0.14 0.1 4.9e-05 0.15 0.09 0.12 0.14 4.0e-07 1.6e-04 4.7e-06 1.5e-06
8 Brain isoform ratio NM_001130504.1 0.05 0.03 4.0e-06 0.07 0.07 0.06 0.07 4.7e-07 6.2e-07 6.1e-06 8.5e-07
9 PL intron excision ratio chr7_113756281_113758674 0.03 0.02 1.9e-03 0.01 0.01 -0 0.01 1.1e-02 1.5e-02 4.4e-01 6.8e-02
10 BLA isoform ratio NM_001130504.1 0.11 0.07 1.9e-04 0.05 0.04 0.04 0.04 7.7e-04 3.7e-03 4.6e-03 2.1e-03
11 PL gene expression Cenpm 0.08 0.05 4.0e-06 0.06 0.05 0.04 0.05 8.6e-07 3.1e-06 1.5e-05 4.9e-06
12 Liver intron excision ratio chr7_113756281_113758674 0.04 0.03 2.2e-03 0.01 0.01 0 0.01 1.1e-02 3.0e-02 2.8e-01 3.6e-02
13 pVTA intron excision ratio chr7_113756281_113758674 0.12 0.1 7.2e-03 0.07 0.02 0.03 0.04 6.1e-04 3.6e-02 2.0e-02 1.1e-02
14 PL isoform ratio NM_001130504.1 0.07 0.04 1.8e-08 0.07 0.06 0.05 0.05 1.8e-08 1.5e-07 2.7e-06 2.3e-06
15 Brain mRNA stability Cenpm 0.08 0.04 1.7e-06 0.02 0.06 0.04 0.04 5.9e-03 4.4e-06 5.3e-05 8.1e-05
16 PL intron excision ratio chr7_113753971_113756189 0.02 0.01 9.4e-03 0 0.02 0 0.01 1.0e-01 6.7e-03 2.4e-01 7.1e-02
17 Brain intron excision ratio chr7_113753971_113756189 0.05 0.03 2.7e-04 0.02 0.04 0.02 0.03 3.8e-03 2.6e-04 2.4e-03 2.0e-03
18 PL mRNA stability Cenpm 0.05 0.03 1.3e-04 0.06 0.03 0.03 0.05 5.9e-07 1.4e-04 1.0e-04 2.7e-06
19 Liver intron excision ratio chr7_113753971_113756189 0.08 0.04 1.6e-07 0.03 0.04 0.03 0.03 1.3e-04 8.3e-06 2.6e-04 1.1e-04
20 Liver gene expression Cenpm 0.06 0.05 1.3e-03 0.03 0.02 0.01 0.02 3.2e-04 2.6e-03 4.2e-02 5.9e-03
21 Liver mRNA stability Cenpm 0.12 0.08 3.0e-06 0.05 0.03 0.04 0.05 1.5e-06 1.4e-04 3.6e-05 6.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.20.40.7-0.70.8-0.5-0.30.80.8-0.20.80.80.8-0.80.60.60.7-0.7-0.5-0.30.3-0.20.1-0.1
Area under the delay curve0.20.20.6-0.80.7-0.6-0.70.60.5-0.80.20.20.2-0.80.70.50.60.1-0.30.1-0.1-0.1-0.4-0.2
BMI with tail1.55.08.02.3-2.32.72.8-1.1-2.42.8-2.5-2.6-2.50.9-0.7-2.5-2.12.52.42.3-2.42.1-1.9-0.9
BMI without tail0.10.21.40.3-0.40.71.1-0.3-0.41.2-0.2-0.3-0.20.6-0.3-0.50.10.30.2-0.1-0.50.10.20.6
Body weight1.35.610.52.9-2.83.03.2-2.1-2.83.2-2.6-2.7-2.71.9-1.8-3.0-2.42.02.11.8-0.71.5-1.0-0.6
Weight adjusted by age0.50.62.20.2-0.2-0.1-0.2-1.0-0.0-0.20.10.10.21.3-1.2-0.1-0.2-0.9-0.7-0.91.5-1.01.30.8
Bone surface0.30.62.7-0.20.2-0.6-0.6-0.20.4-0.60.60.60.60.1-0.80.60.3-1.6-0.7-0.81.3-0.81.40.8
Bone volume0.10.10.80.00.1-0.1-0.1-0.20.2-0.10.20.20.20.1-0.60.20.0-0.9-0.4-0.40.6-0.50.70.4
Breakpoint value in progressive ratio session0.20.20.6-0.10.1-0.1-0.10.70.1-0.10.20.20.4-0.60.70.10.20.30.40.3-0.80.6-0.5-0.8
Number of licking bursts0.40.41.1-0.90.6-0.9-1.00.40.6-1.10.70.70.7-0.30.30.70.7-0.5-0.6-0.60.3-0.40.40.4
Context. condit. distance diff. score5.46.512.03.5-3.13.02.9-3.0-3.02.9-3.1-3.1-3.12.7-2.8-2.8-3.22.01.81.4-0.10.9-0.3-0.5
Locomotion velocity, session 10.60.72.10.1-0.4-0.4-0.8-1.0-0.1-0.90.10.10.10.7-1.30.0-0.1-1.4-0.5-0.71.4-0.91.41.3
Locomotion distance, session 12.43.16.8-1.91.6-2.2-2.60.71.7-2.61.91.91.9-0.70.41.71.7-2.0-1.9-1.81.3-1.71.51.4
Locomotion velocity, session 20.30.31.30.6-0.70.60.4-0.9-0.60.4-0.7-0.7-0.70.5-1.1-0.5-0.6-0.40.10.1-0.1-0.10.50.7
Locomotion distance, session 22.13.06.0-2.32.0-2.1-2.32.31.9-2.31.91.91.9-2.42.01.81.9-1.2-0.9-0.5-0.4-0.2-0.2-0.2
Locomotion velocity, session 30.50.52.10.5-0.50.30.0-1.2-0.30.0-0.4-0.4-0.41.1-1.5-0.3-0.3-0.8-0.5-0.50.9-0.91.11.1
Locomotion distance, session 31.51.73.1-1.21.1-1.5-1.70.01.3-1.81.31.31.30.1-0.01.01.2-1.2-1.7-1.61.2-1.71.31.4
Stereotopy head waving bouts, day 30.60.71.21.1-1.11.11.1-0.9-1.01.1-1.0-1.0-1.00.5-1.1-1.0-1.1-0.10.70.70.30.40.1-0.2
Stereotopy head waving duration, day 32.83.46.02.5-2.42.32.2-2.2-2.22.2-2.2-2.2-2.21.8-2.4-1.9-2.20.31.31.00.50.60.3-0.0
Locomotion velocity, session 70.10.20.60.2-0.20.30.3-0.7-0.20.3-0.4-0.4-0.40.4-0.6-0.70.0-0.0-0.3-0.1-0.1-0.50.40.8
Locomotion distance, session 70.40.51.7-0.80.8-0.4-0.30.90.5-0.30.20.20.2-1.31.0-0.20.70.5-0.10.6-1.20.3-1.0-0.4
Stereotopy head waving bouts, day 72.93.39.32.4-2.21.61.6-2.9-1.81.5-1.5-1.5-1.52.5-3.1-1.6-2.0-0.70.4-0.22.1-0.61.91.1
Stereotopy head waving duration, day 72.22.77.22.1-1.91.61.7-2.6-1.61.7-1.3-1.3-1.32.5-2.7-1.3-1.6-0.50.2-0.31.9-0.71.71.3
Locomotion velocity, session 82.12.55.92.2-2.21.61.1-1.6-2.01.1-1.9-1.9-1.91.7-1.6-1.5-2.41.11.71.1-0.31.1-0.3-1.0
Locomotion distance, session 80.71.12.41.5-1.31.10.9-1.3-1.20.9-1.3-1.3-1.31.0-1.4-0.9-1.50.50.60.40.10.2-0.0-0.2
Degree of sensitization distance3.43.45.71.4-1.32.02.20.0-1.62.2-1.9-1.9-1.9-0.40.3-1.7-1.42.22.12.4-2.32.2-2.3-1.9
Degree of sensitization stereotypy2.12.36.81.9-1.71.21.1-2.5-1.41.1-1.1-1.1-1.12.3-2.6-1.3-1.5-0.60.1-0.52.1-0.81.81.2
Conditioned locomotion0.60.72.11.0-0.80.80.7-1.4-0.80.7-1.0-1.0-1.01.4-1.3-0.8-0.90.3-0.1-0.10.8-0.50.30.4
Cocaine response after cond. corrected0.10.10.40.2-0.20.20.2-0.5-0.10.2-0.0-0.0-0.00.6-0.6-0.1-0.1-0.2-0.2-0.3-0.0-0.30.50.6
Cocaine response after cond. not corrected0.10.20.70.2-0.20.30.2-0.6-0.10.2-0.1-0.1-0.10.6-0.80.2-0.1-0.4-0.3-0.40.2-0.50.60.8
Cocaine response before conditioning0.00.10.3-0.20.2-0.1-0.20.10.2-0.2-0.0-0.0-0.0-0.4-0.10.60.2-0.3-0.3-0.20.2-0.20.00.2
Saline control response0.60.83.40.5-0.60.1-0.1-1.3-0.3-0.1-0.5-0.5-0.51.3-1.70.3-0.5-0.9-0.5-0.91.8-1.01.21.0
Bone: connectivity density0.10.20.6-0.50.5-0.3-0.00.60.50.00.50.60.5-0.80.40.20.4-0.5-0.2-0.10.4-0.00.0-0.3
Bone: cortical apparent density0.60.81.5-1.21.1-1.1-1.20.91.0-1.20.90.90.9-1.00.90.71.2-0.6-0.6-0.30.2-0.30.00.0
Bone: cortical area1.21.93.11.7-1.81.71.6-1.3-1.71.6-1.6-1.6-1.61.3-1.4-1.6-1.21.01.31.1-0.40.9-0.3-0.3
Bone: cortical porosity0.50.51.20.9-0.81.01.1-0.8-0.81.1-1.0-1.0-1.00.8-0.9-0.6-0.50.30.40.30.30.10.00.1
Bone: cortical porosity1.11.22.71.4-1.31.51.6-1.2-1.21.6-1.4-1.3-1.41.2-1.3-1.2-0.90.50.80.60.30.40.00.0
Bone: cortical thickness0.61.03.10.1-0.40.70.70.7-0.70.7-0.6-0.6-0.6-0.50.8-0.8-0.11.61.41.4-1.71.6-1.6-1.4
Bone: cortical thickness0.91.03.40.3-0.60.60.50.4-0.80.4-0.7-0.7-0.7-0.20.7-0.7-0.51.81.41.3-1.91.5-1.5-1.4
Bone: cortical tissue density0.50.71.4-1.21.0-1.0-1.10.90.9-1.20.90.90.9-1.10.90.71.1-0.6-0.6-0.30.2-0.3-0.0-0.1
Condit. Reinf. active minus inactive responses0.30.32.0-0.60.6-0.3-0.50.90.4-0.50.20.20.2-1.40.70.30.5-0.20.00.5-0.90.4-0.5-0.4
Condit. Reinf. active-inactive response ratio0.20.20.30.5-0.50.50.4-0.4-0.50.3-0.6-0.6-0.6-0.1-0.5-0.6-0.4-0.00.40.5-0.20.3-0.0-0.0
Condit. Reinf. active responses1.11.33.8-1.61.5-1.1-1.31.71.3-1.31.01.01.0-1.91.31.41.3-0.6-0.6-0.1-0.8-0.1-0.4-0.1
Condit. Reinf. inactive responses2.02.44.4-2.12.1-1.7-1.71.91.9-1.71.71.71.7-1.81.72.01.8-0.8-1.2-0.8-0.1-0.6-0.10.2
Incentive salience index mean0.60.83.8-1.11.0-0.7-0.81.40.8-0.80.50.50.5-2.01.20.60.9-0.1-0.10.5-1.20.4-0.8-0.6
Condit. Reinf. lever presses0.60.93.4-1.21.3-0.9-0.91.31.0-0.90.70.70.7-1.81.00.91.1-0.5-0.60.1-0.9-0.1-0.5-0.1
Condit. Reinf. active minus inactive responses0.40.41.7-0.1-0.0-0.2-0.40.8-0.2-0.5-0.1-0.1-0.0-1.10.8-0.1-0.20.30.81.0-0.81.1-0.9-1.3
Condit. Reinf. active-inactive response ratio0.60.72.30.0-0.10.10.11.0-0.30.1-0.0-0.00.0-1.41.0-0.4-0.20.41.11.3-1.01.4-1.0-1.5
Condit. Reinf. active responses0.40.51.10.9-0.90.50.1-0.4-0.90.0-0.9-0.9-0.90.0-0.4-0.7-1.10.41.01.0-0.40.9-0.5-0.9
Condit. Reinf. inactive responses0.70.91.91.2-1.20.90.5-1.3-1.20.4-1.4-1.4-1.41.1-1.3-0.9-1.20.50.60.5-0.10.2-0.10.1
Condit. Reinf. lever presses0.20.31.6-0.30.5-0.6-0.61.00.4-0.60.50.50.5-1.30.70.60.1-0.50.10.30.20.5-0.2-0.7
Condit. Reinf. lever reinforcers received0.20.31.00.6-0.60.2-0.00.0-0.6-0.1-0.6-0.6-0.6-0.5-0.1-0.4-0.80.10.91.0-0.30.9-0.5-1.0
Conditioned reinforcement - actives0.30.30.90.4-0.60.2-0.2-0.8-0.6-0.4-0.7-0.7-0.70.9-0.8-0.6-0.60.40.20.3-0.00.0-0.00.2
Conditioned reinforcement - inactives0.40.41.2-0.30.2-0.2-0.50.80.0-0.6-0.0-0.0-0.1-1.00.90.20.10.50.60.8-1.00.9-1.0-1.1
Conditioned locomotion1.61.92.91.5-1.51.51.3-1.0-1.61.1-1.6-1.6-1.60.9-0.8-1.7-1.61.51.51.6-1.31.2-1.0-0.9
Patch foraging indifference point 0 sec0.30.41.6-0.60.7-0.5-0.41.20.6-0.30.70.70.7-1.31.00.80.6-0.50.10.10.20.4-0.2-0.5
Patch foraging indifference point AUC0.20.31.2-0.50.4-0.7-1.00.30.4-1.10.50.50.5-0.40.20.30.5-0.5-0.3-0.10.0-0.20.30.6
Delay disc. indifference point, 0s delay1.01.01.71.0-1.01.21.2-0.6-1.11.2-1.3-1.3-1.30.5-0.5-0.8-1.11.11.01.0-0.90.8-1.0-1.0
Delay disc. indifference point, 16s delay1.51.52.4-1.51.5-1.5-1.51.31.5-1.51.31.31.3-1.41.41.31.4-0.8-1.1-0.70.7-0.60.30.5
Delay disc. indifference point, 2s delay0.20.20.7-0.0-0.00.40.3-0.0-0.20.3-0.6-0.6-0.6-0.20.2-0.5-0.10.80.20.6-0.80.3-0.8-0.4
Delay disc. indifference point, 24s delay0.50.51.3-0.60.4-0.7-1.0-0.30.5-1.10.60.60.70.2-0.30.20.7-0.8-0.8-0.70.8-0.80.90.9
Delay disc. indifference point, 4s delay0.40.41.1-0.30.1-0.0-0.20.8-0.1-0.2-0.2-0.2-0.3-0.90.80.1-0.10.60.71.0-1.01.0-1.1-1.0
Delay disc. indifference point, 8s delay0.80.81.6-1.31.2-1.0-1.10.91.1-1.20.80.80.8-1.21.10.91.2-0.2-0.8-0.40.2-0.4-0.10.1
Indifference point function ln k0.91.32.51.5-1.31.41.5-1.0-1.21.6-1.3-1.3-1.30.9-1.0-1.3-1.60.70.90.7-0.10.5-0.3-1.0
Indifference point function log k0.91.32.51.5-1.31.41.5-1.0-1.21.6-1.3-1.3-1.30.9-1.0-1.3-1.60.70.90.7-0.10.5-0.3-1.0
Patch foraging total patch changes 0 sec0.30.61.8-0.80.8-0.7-0.61.30.8-0.50.90.90.9-1.31.11.00.7-0.5-0.0-0.00.30.3-0.1-0.4
Patch foraging total patch changes 12 sec0.10.10.5-0.10.00.10.00.5-0.00.00.10.00.1-0.70.30.10.0-0.20.40.6-0.20.6-0.40.1
Patch foraging total patch changes 18 sec0.20.31.4-0.30.3-0.4-0.41.00.2-0.50.20.20.2-1.20.80.40.0-0.00.50.6-0.40.8-0.6-0.7
Patch foraging total patch changes 24 sec0.20.30.5-0.50.5-0.6-0.60.50.6-0.60.70.70.7-0.30.40.60.7-0.6-0.3-0.30.1-0.20.20.6
Patch foraging total patch changes 6 sec0.20.30.9-0.50.3-0.5-0.80.90.3-0.70.50.50.5-0.80.60.70.2-0.30.40.2-0.40.6-0.10.3
Patch foraging time to switch 0 sec0.10.20.7-0.10.30.20.7-0.00.30.80.10.10.1-0.3-0.20.20.3-0.5-0.5-0.30.5-0.50.10.7
Patch foraging water rate 0 sec0.10.20.5-0.2-0.0-0.4-0.60.70.0-0.60.40.40.40.00.60.5-0.10.20.60.1-0.50.7-0.1-0.7
Patch foraging water rate 12 sec0.30.51.0-0.50.5-0.8-0.80.40.6-0.81.01.01.0-0.10.50.90.7-0.8-0.4-0.70.3-0.40.80.4
Patch foraging water rate 18 sec1.11.53.1-1.11.1-1.4-1.51.01.2-1.41.81.81.8-0.70.81.41.1-1.7-0.8-1.10.7-0.61.10.1
Patch foraging water rate 24 sec0.10.10.70.2-0.40.10.10.3-0.40.20.20.20.20.10.20.0-0.3-0.10.80.4-0.60.8-0.0-0.1
Patch foraging water rate 6 sec1.11.63.4-1.00.9-1.5-1.60.21.1-1.61.31.31.3-0.1-0.21.31.0-1.8-1.3-1.41.5-1.31.71.2
Seeking ratio, delayed vs. immediate footshock2.93.37.0-2.22.3-2.0-1.82.32.2-1.82.12.02.1-2.62.51.92.3-1.1-1.3-0.80.1-0.50.10.6
Distance traveled before self-admin0.91.03.6-0.20.40.20.31.20.00.3-0.3-0.3-0.2-1.51.7-0.30.11.30.81.3-1.81.3-1.9-1.0
Distance traveled after self-admin0.30.41.20.2-0.30.30.10.5-0.40.1-0.4-0.4-0.3-0.80.5-0.2-0.20.60.91.0-0.91.1-1.0-0.7
Extensor digitorum longus weight0.10.41.2-0.70.5-0.8-0.60.30.6-0.60.60.60.60.10.21.10.9-0.6-0.6-0.90.6-0.50.60.7
Bone: elastic displacement0.50.51.90.5-0.60.10.0-1.1-0.30.0-0.0-0.0-0.01.4-1.2-0.2-0.3-0.8-0.3-0.81.0-0.71.41.1
Bone: elastic work1.92.44.62.1-2.01.92.0-1.5-1.92.1-1.6-1.6-1.61.5-1.6-1.6-1.90.81.51.0-0.41.0-0.0-0.4
Bone: endosteal estimation1.32.810.12.2-1.81.31.1-2.7-1.41.1-1.3-1.3-1.32.5-3.2-0.9-1.6-1.3-0.1-0.61.9-1.02.01.6
Bone: endosteal perimeter2.04.212.92.7-2.32.01.9-3.4-1.91.9-1.9-1.9-1.93.0-3.6-1.7-1.9-0.70.1-0.31.8-1.01.81.7
Epididymis fat weight2.65.910.63.3-2.82.92.9-3.1-2.72.9-2.8-2.9-2.92.8-2.8-3.0-2.81.61.31.2-0.50.4-0.30.9
Delta time in closed arm before/after self-admin1.51.42.51.3-1.11.10.6-0.6-1.20.5-1.5-1.5-1.60.5-0.4-1.2-1.51.61.21.4-1.31.1-1.4-0.9
Delta time in open arm before/after self-admin0.50.51.4-0.40.4-0.4-0.2-0.30.5-0.20.70.70.70.3-0.40.40.3-1.0-0.9-1.11.0-1.01.20.5
Diff in mean of infusions in LGA sessions0.40.51.3-1.20.8-0.7-0.80.90.7-0.80.70.70.6-0.91.00.70.3-0.1-0.3-0.0-0.40.0-0.4-0.5
Delay discount exponential model param0.30.30.80.8-0.70.70.8-0.6-0.60.9-0.3-0.3-0.30.8-0.6-0.5-0.7-0.00.4-0.0-0.00.20.30.1
Extinction: sum of active levers before priming0.10.10.3-0.10.0-0.1-0.20.3-0.0-0.3-0.0-0.00.0-0.30.4-0.0-0.10.30.20.3-0.60.3-0.3-0.6
Active lever presses in extinction session 60.20.20.60.2-0.40.30.20.0-0.40.2-0.5-0.5-0.50.1-0.0-0.3-0.40.50.60.5-0.80.6-0.5-0.8
Bone: final force1.42.34.11.4-1.41.71.7-0.2-1.61.7-1.6-1.6-1.60.0-0.4-1.8-1.51.62.02.0-1.21.9-1.5-1.7
Bone: final moment1.62.54.51.5-1.61.81.7-0.4-1.81.7-1.7-1.7-1.70.2-0.6-1.8-1.51.62.12.0-1.22.0-1.4-1.7
Food consumed during 24 hour testing period1.51.82.91.0-1.41.61.7-0.6-1.51.7-1.5-1.5-1.50.4-0.4-1.7-1.21.51.61.5-1.11.4-1.1-1.0
Glucose0.20.31.1-0.60.8-0.5-0.21.00.8-0.10.60.60.6-1.00.80.80.7-0.4-0.4-0.1-0.3-0.0-0.20.2
Heart weight2.83.96.62.3-2.22.22.0-0.8-2.32.0-2.1-2.1-2.10.7-0.5-1.7-2.42.62.62.1-1.52.3-1.8-1.7
Delay discount hyperbolic model param0.20.20.40.6-0.50.40.6-0.4-0.40.6-0.0-0.0-0.00.6-0.5-0.3-0.5-0.20.2-0.20.2-0.00.50.2
Intermittent access intake day 1-15 change0.30.30.8-0.50.6-0.9-0.80.60.6-0.80.50.50.4-0.60.70.70.7-0.2-0.3-0.20.2-0.1-0.10.4
Intermittent access intake escalation0.40.40.9-0.60.7-1.0-0.90.70.6-0.90.60.60.4-0.70.70.80.7-0.3-0.3-0.30.3-0.1-0.10.4
Intermittent access intake escalation 20.20.20.5-0.20.3-0.7-0.60.20.3-0.70.30.30.2-0.20.10.70.5-0.3-0.3-0.40.7-0.30.10.3
Intermitt. access day 1 inactive lever presses1.01.13.50.6-0.60.80.90.5-0.80.9-0.6-0.6-0.6-0.60.5-0.4-1.11.11.51.4-1.71.6-1.2-1.9
Intermitt. access day 15 inactive lever presses2.12.36.20.6-0.80.80.60.9-1.10.5-1.0-1.0-1.1-1.11.1-0.8-1.21.92.12.2-2.52.4-2.3-2.4
Intermitt. access escalation Index0.10.10.5-0.20.1-0.10.00.60.10.00.10.10.0-0.60.70.10.00.30.40.5-0.20.5-0.6-0.6
Intermittent access day 1 total infusions0.91.01.70.9-1.01.10.9-0.5-1.10.8-1.1-1.1-1.00.5-0.3-1.3-0.91.21.21.2-1.21.1-0.9-0.9
Intermittent access day 15 total infusions0.20.20.6-0.10.0-0.2-0.30.5-0.1-0.4-0.0-0.0-0.1-0.40.7-0.00.20.50.50.6-0.50.7-0.7-0.4
Intermittent access terminal intake (last 3 days)0.00.00.10.2-0.20.0-0.2-0.1-0.2-0.3-0.3-0.3-0.30.2-0.0-0.2-0.00.40.20.3-0.10.2-0.3-0.0
Intermittent access total infusions0.30.30.60.3-0.40.50.4-0.1-0.50.3-0.5-0.5-0.50.10.1-0.6-0.30.80.70.8-0.60.7-0.7-0.6
Intermittent access day 1 locomotion0.50.51.20.4-0.50.70.7-0.1-0.60.6-0.7-0.7-0.70.20.0-0.8-0.80.90.81.0-1.10.8-0.9-1.1
Intermittent access day 15 total locomotion0.10.10.70.2-0.30.30.2-0.1-0.30.2-0.2-0.2-0.30.0-0.1-0.4-0.40.30.40.4-0.30.4-0.4-0.8
Intermittent access total locomotion0.50.61.20.4-0.50.70.70.1-0.60.6-0.6-0.6-0.6-0.30.2-0.9-0.71.00.91.1-1.11.0-0.9-1.0
Intermittent access standard deviation0.80.91.71.0-0.80.90.90.0-0.90.9-1.0-1.0-0.9-0.10.3-0.8-0.61.31.21.3-1.01.3-1.2-0.7
Left kidney weight10.128.545.26.7-6.76.35.8-4.9-6.75.6-6.3-6.3-6.44.3-4.7-6.3-6.34.15.44.6-1.93.9-2.3-2.3
Right kidney weight11.131.047.86.9-6.96.55.8-4.9-6.95.7-6.6-6.6-6.64.2-4.5-6.5-6.74.75.85.0-2.74.3-2.8-2.5
Cocaine induced anxiety1.01.22.90.6-0.81.21.40.4-1.01.5-0.8-0.8-0.7-0.40.6-0.8-0.61.41.61.5-1.41.7-1.3-0.8
Post-drug Anxiety0.30.31.00.3-0.50.60.90.3-0.50.9-0.3-0.3-0.3-0.20.3-0.1-0.30.61.00.7-0.61.0-0.5-0.4
Baseline Anxiety1.11.22.2-1.11.0-1.2-1.20.11.2-1.21.11.10.90.0-0.01.21.1-1.4-1.5-1.41.4-1.41.10.8
Tail length0.20.61.6-0.50.5-0.6-0.4-0.10.7-0.30.90.90.90.5-0.20.60.9-0.9-0.9-1.21.2-1.01.10.8
Length with tail0.20.91.91.4-1.21.01.1-1.3-1.01.1-0.8-0.8-0.81.2-1.4-1.2-1.0-0.10.40.21.1-0.00.5-0.0
Length without tail0.71.62.91.7-1.51.51.2-1.0-1.51.1-1.5-1.5-1.50.4-0.9-1.7-1.70.61.31.50.01.1-0.6-0.9
Times rat made contact with spout0.70.81.80.6-1.00.70.5-0.3-1.00.4-1.1-1.1-1.10.4-0.2-0.9-1.01.41.21.0-1.21.1-1.0-0.9
Lifetime Intake1.11.22.60.7-0.81.00.80.1-1.00.8-1.0-1.0-1.0-0.10.4-1.1-0.81.61.41.6-1.41.5-1.5-1.4
Liver weight, left0.81.43.91.5-1.11.11.1-1.9-0.91.1-1.0-1.0-1.01.7-2.0-1.2-1.0-0.4-0.2-0.21.2-0.81.11.0
Liver weight, right2.13.58.52.3-2.02.02.1-2.9-1.82.1-2.1-2.1-2.12.7-2.9-2.1-1.70.30.20.21.2-0.60.61.4
Locomotor activity1.52.54.21.9-2.12.02.0-1.9-1.92.0-1.7-1.7-1.71.8-1.9-1.9-1.70.51.20.70.30.50.30.1
Locomotor testing distance0.00.00.2-0.30.1-0.1-0.1-0.00.1-0.10.20.20.2-0.1-0.0-0.10.4-0.4-0.2-0.20.5-0.20.30.2
Locomotor testing rearing1.11.72.71.5-1.61.61.5-1.6-1.51.4-1.6-1.6-1.61.6-1.5-1.5-1.41.00.90.8-0.20.4-0.40.1
Locomotion in novel chamber1.61.95.0-0.00.3-1.0-1.0-1.20.6-1.10.70.70.81.7-1.41.10.4-1.5-1.7-2.12.2-2.12.21.9
Locomotion in novel chamber post-restriction0.81.01.7-0.91.3-1.1-1.10.61.2-1.11.21.11.2-0.40.61.01.2-0.9-1.3-1.10.7-1.10.60.8
Fecal boli incidents, locomotor time 10.20.30.6-0.80.7-0.6-0.40.60.6-0.40.60.60.6-0.20.60.60.5-0.5-0.4-0.4-0.1-0.20.30.0
Change in fecal boli incidents, locomotor task0.50.51.70.6-0.80.30.2-1.3-0.60.1-0.3-0.3-0.31.2-1.3-0.8-0.3-0.2-0.0-0.21.1-0.50.60.9
Time >=10cm from walls, locomotor time 10.00.00.20.2-0.10.30.4-0.1-0.10.4-0.1-0.1-0.1-0.0-0.2-0.20.0-0.10.10.3-0.00.1-0.3-0.2
Bouts of movement, locomotor time 10.10.10.6-0.1-0.10.40.4-0.1-0.20.4-0.2-0.2-0.2-0.30.0-0.80.00.50.10.4-0.50.2-0.2-0.0
Total resting periods, locomotor time 10.20.20.7-0.40.30.30.40.50.10.40.00.0-0.0-0.80.7-0.50.30.70.20.6-0.80.4-0.6-0.5
Rest time, locomotor task time 10.91.03.10.2-0.10.81.00.6-0.41.0-0.6-0.6-0.7-0.81.0-0.7-0.31.60.91.3-1.81.2-1.6-1.2
Distance moved, locomotor task time 10.50.61.91.0-0.90.50.4-1.2-0.80.3-0.9-0.9-0.91.3-1.4-0.5-1.0-0.20.20.00.4-0.20.4-0.0
Vertical activity count, locomotor time 10.00.00.30.1-0.2-0.2-0.2-0.1-0.1-0.2-0.1-0.1-0.10.2-0.30.1-0.2-0.40.0-0.10.5-0.00.1-0.1
Time >=10cm from walls, locomotor time 20.10.10.3-0.20.4-0.2-0.2-0.00.4-0.10.30.30.30.2-0.10.20.6-0.5-0.6-0.40.5-0.50.40.3
Bouts of movement, locomotor time 20.70.81.90.1-0.20.81.00.4-0.51.0-0.6-0.6-0.6-0.70.7-1.2-0.51.30.91.2-1.41.1-1.4-0.9
Total resting periods, locomotor time 20.70.71.9-0.1-0.10.60.80.6-0.40.8-0.5-0.5-0.5-0.80.9-1.0-0.41.30.91.2-1.31.2-1.4-1.0
Rest time, locomotor task time 20.10.20.5-0.60.5-0.3-0.30.60.4-0.30.40.40.4-0.70.70.20.40.2-0.00.1-0.40.2-0.20.0
Distance moved, locomotor task time 20.81.01.91.3-1.10.90.8-1.3-1.10.8-1.4-1.4-1.41.3-1.3-1.0-1.00.50.40.3-0.30.0-0.0-0.3
Vertical activity count, locomotor time 20.40.41.20.9-0.90.50.6-0.9-0.80.6-0.8-0.8-0.91.1-0.9-0.7-0.60.20.40.20.00.10.1-0.2
Light reinforcement 10.30.62.40.8-0.50.1-0.2-1.2-0.3-0.2-0.4-0.4-0.40.8-1.50.1-0.1-1.0-0.4-0.51.4-0.81.20.7
Light reinforcement 20.50.61.31.0-0.81.01.0-1.1-0.91.0-1.1-1.1-1.10.5-1.1-1.0-0.40.20.30.60.20.0-0.30.1
Bone: marrow area1.42.910.62.2-1.91.41.1-2.7-1.51.1-1.4-1.4-1.42.5-3.3-0.9-1.7-1.3-0.0-0.51.9-0.92.01.5
Bone: maximum diameter3.36.110.83.3-3.23.02.8-2.9-3.12.8-2.9-2.9-2.92.7-3.0-2.7-2.61.22.11.50.01.10.0-0.2
Bone: maximum force2.44.26.02.2-2.32.42.3-1.0-2.42.3-2.3-2.3-2.30.9-1.2-2.3-2.22.02.52.3-1.62.1-1.5-1.6
Bone: maximum moment2.74.66.72.4-2.52.62.4-1.2-2.52.4-2.4-2.4-2.41.1-1.4-2.4-2.32.02.62.3-1.62.2-1.4-1.6
Mean time between licks in bursts0.40.61.2-1.10.9-1.0-1.00.70.9-0.90.80.80.8-0.40.91.11.0-0.1-0.7-0.60.3-0.5-0.10.2
Mean num. licks in bursts1.51.72.51.6-1.51.51.4-1.1-1.61.4-1.6-1.6-1.61.0-0.9-1.5-1.61.41.31.2-0.81.0-0.8-0.7
Cd content in liver1.11.25.21.3-1.41.10.8-1.5-1.30.8-1.1-1.1-1.12.3-1.1-0.9-1.41.30.7-0.00.00.2-0.00.5
Co content in liver0.50.61.70.6-0.80.80.5-0.3-0.80.5-0.8-0.8-0.81.0-0.0-0.5-0.71.31.00.6-0.60.9-0.9-1.1
Cu content in liver3.34.06.3-2.22.5-2.4-2.22.02.4-2.12.42.52.4-1.81.62.42.2-2.0-1.9-1.41.0-1.20.70.5
Fe content in liver0.20.20.80.6-0.40.40.4-0.5-0.20.4-0.2-0.2-0.20.5-0.90.1-0.3-0.9-0.1-0.30.8-0.30.90.2
K content in liver0.60.61.7-0.60.8-0.8-0.81.30.7-0.80.80.80.8-1.11.00.80.4-0.8-0.00.2-0.60.4-0.3-0.6
Mg content in liver1.11.24.2-0.91.2-1.0-0.91.91.0-0.91.01.11.0-2.11.61.20.8-0.7-0.00.5-0.60.6-0.7-0.8
Mn content in liver0.20.30.70.8-0.40.3-0.0-0.9-0.3-0.1-0.5-0.5-0.50.8-0.7-0.3-0.8-0.1-0.2-0.10.4-0.40.40.7
Na content in liver2.22.33.8-1.71.9-1.8-1.61.71.9-1.61.91.91.9-1.51.51.81.5-1.3-1.3-1.10.4-0.80.40.1
Rb content in liver0.10.10.2-0.0-0.0-0.0-0.20.4-0.1-0.2-0.1-0.1-0.1-0.40.40.1-0.0-0.10.40.4-0.10.5-0.3-0.4
Se content in liver0.70.92.1-0.81.0-1.0-1.00.31.0-1.01.10.91.1-0.00.11.00.9-1.4-1.2-1.00.6-1.11.00.9
Sr content in liver0.70.71.4-1.20.9-1.0-1.00.60.9-1.11.01.00.9-0.20.80.91.10.2-0.8-0.9-0.3-0.60.00.3
Zn content in liver1.11.21.8-1.01.1-1.3-1.20.51.2-1.21.31.31.3-0.20.31.31.0-1.3-1.2-1.21.3-1.11.00.7
Bone: minimum diameter0.61.23.91.4-1.31.11.1-1.7-1.11.1-1.0-1.0-1.01.5-2.0-0.8-0.8-0.40.2-0.00.8-0.30.91.0
Time in familiar zone, hab. session 10.10.10.30.1-0.2-0.1-0.3-0.6-0.2-0.3-0.2-0.2-0.20.6-0.4-0.3-0.1-0.1-0.2-0.20.0-0.30.50.6
Time in novel zone, hab. session 10.80.71.61.2-1.11.11.2-0.9-0.91.3-0.7-0.7-0.71.3-1.0-0.4-1.20.60.6-0.00.40.20.1-0.1
Total zone transitions, hab. session 13.34.69.3-2.42.1-2.7-3.01.02.3-3.12.32.32.3-1.00.82.22.1-2.3-2.3-2.11.6-2.01.71.5
Total locomotion distance, hab. session 12.53.57.4-1.21.2-1.9-2.2-0.41.5-2.31.61.61.60.1-0.81.71.2-2.7-2.3-2.42.2-2.42.62.4
Locomotion velocity, hab. session 12.43.47.1-1.51.5-2.1-2.40.21.7-2.41.71.71.7-0.5-0.31.91.5-2.7-2.2-2.11.8-2.12.22.0
Time in familiar zone, hab. session 20.60.62.60.1-0.1-0.1-0.0-1.20.10.0-0.0-0.0-0.01.3-1.00.10.3-0.4-1.0-1.11.1-1.41.21.6
Time in novel zone, hab. session 20.40.41.70.3-0.40.20.00.6-0.4-0.0-0.2-0.2-0.2-0.40.4-0.2-0.80.51.10.9-0.71.2-0.8-1.3
Total zone transitions, hab. session 20.60.83.2-1.00.8-1.3-1.70.90.9-1.80.80.80.8-0.90.61.10.6-1.0-0.5-0.30.3-0.20.1-0.2
Total locomotion distance, hab. session 20.50.71.7-0.90.8-1.1-1.30.70.9-1.30.90.90.9-0.80.51.10.6-0.9-0.6-0.6-0.0-0.40.30.3
Locomotion velocity, hab. session 21.01.33.0-1.31.2-1.5-1.71.01.3-1.71.21.21.2-1.10.71.51.0-1.3-1.0-0.80.1-0.70.50.5
Novel to familiar place preference ratio2.32.44.92.1-2.01.71.7-2.0-1.71.7-1.4-1.4-1.42.2-1.9-1.7-2.10.71.00.21.20.30.8-0.1
Novelty place preference3.13.26.72.3-2.32.02.0-2.4-2.02.0-1.7-1.7-1.72.6-2.2-2.0-2.30.91.10.21.20.30.80.1
Time in novel zone, NPP test3.83.98.02.6-2.62.22.2-2.6-2.32.2-1.9-1.9-1.92.8-2.4-2.3-2.61.11.40.41.10.40.8-0.0
Total zone transitions, NPP test2.53.59.2-1.91.7-2.5-3.00.91.9-3.02.02.02.0-0.90.72.11.5-2.0-1.8-1.81.3-1.51.41.1
Total locomotion distance, NPP test1.11.63.6-1.31.2-1.7-1.90.81.3-1.91.51.51.5-0.90.51.51.0-1.4-1.1-1.10.5-0.90.90.6
Locomotion velocity, NPP test1.92.74.9-1.81.7-2.1-2.21.01.8-2.21.91.91.9-1.20.71.91.6-1.8-1.7-1.50.7-1.41.11.1
Intraocular pressure0.20.30.90.6-0.60.60.5-0.8-0.60.5-0.5-0.5-0.50.5-0.7-1.0-0.50.40.20.1-0.1-0.10.1-0.1
Delta distance traveled before/after self-admin0.60.73.30.9-1.10.30.0-1.4-0.8-0.1-0.5-0.5-0.51.5-1.8-0.4-0.8-0.60.2-0.30.9-0.31.00.4
Delta ambulatory time before/after self-admin0.70.83.70.9-1.30.3-0.1-1.4-1.0-0.2-0.5-0.5-0.61.7-1.9-0.3-0.9-0.70.4-0.31.0-0.11.10.2
Parametrial fat weight0.20.41.10.3-0.30.70.70.1-0.40.7-0.6-0.6-0.6-0.20.3-0.6-0.51.00.60.8-0.80.7-1.1-0.9
Pavlov. Cond. lever latency0.81.12.51.6-1.41.01.0-1.4-1.21.0-0.9-0.9-0.91.5-1.1-1.1-1.40.70.70.10.70.20.3-0.1
Pavlov. Cond. magazine entry latency0.91.22.9-1.71.3-0.9-1.01.71.1-1.00.80.80.8-1.71.70.91.30.2-0.30.2-1.40.3-1.0-0.4
Pavlov. Cond. change in total contacts1.31.44.0-1.61.3-1.0-1.11.91.1-1.20.90.90.9-2.01.71.01.20.2-0.10.4-1.70.6-1.1-0.8
Pavlov. Cond. index score0.70.93.2-1.31.0-0.5-0.51.60.7-0.60.30.30.3-1.71.50.40.90.50.20.7-1.80.7-1.4-0.8
Pavlov. Cond. latency score0.60.82.6-1.20.9-0.4-0.51.50.6-0.50.30.30.3-1.51.40.40.90.40.20.6-1.60.7-1.2-0.7
Pavlov. Cond. lever contacts1.11.33.5-1.71.6-1.1-1.11.71.3-1.10.90.90.9-1.91.61.11.4-0.3-0.60.0-1.20.0-0.7-0.2
Pavlov. Cond. magazine entry number0.70.92.41.5-1.10.70.8-1.5-0.90.8-0.5-0.5-0.51.5-1.5-0.5-1.1-0.50.1-0.31.5-0.41.10.4
Pavlov. Cond. intertrial magazine entries0.80.91.6-1.31.0-1.2-1.21.31.0-1.21.21.21.2-0.91.11.21.1-0.7-0.4-0.40.5-0.10.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.03.1-1.51.2-0.7-0.81.60.9-0.80.50.50.5-1.81.60.61.20.3-0.10.5-1.60.5-1.2-0.6
Pavlov. Cond. response bias1.11.34.1-1.71.4-0.8-0.91.81.1-0.90.60.60.6-2.01.70.71.30.2-0.30.5-1.60.4-1.2-0.6
Pavlov. Cond. lever latency0.60.92.50.6-1.01.00.8-1.4-1.00.8-1.1-1.1-1.11.6-0.9-1.3-0.51.40.30.2-0.4-0.1-0.30.6
Pavlov. Cond. magazine entry latency3.43.910.7-2.32.3-2.0-1.73.32.1-1.62.42.42.4-2.92.92.02.0-1.2-0.5-0.0-0.10.5-0.6-1.3
Pavlov. Cond. change in total contacts1.11.56.0-0.50.8-0.6-0.42.30.6-0.40.80.80.8-2.41.90.80.2-0.50.91.2-0.51.6-1.1-2.3
Pavlov. Cond. index score2.02.67.4-1.71.8-1.7-1.42.71.7-1.41.91.81.9-2.72.31.81.3-1.2-0.30.10.10.6-0.4-1.3
Pavlov. Cond. latency score2.53.19.0-1.92.0-1.8-1.63.01.8-1.52.02.02.0-2.92.51.91.5-1.2-0.30.1-0.10.6-0.6-1.4
Pavlov. Cond. lever contacts0.70.93.6-0.61.0-0.9-0.71.60.9-0.61.01.01.0-1.91.11.20.5-1.3-0.10.10.30.40.0-0.9
Pavlov. Cond. magazine entry number2.02.47.31.6-1.81.51.2-2.7-1.61.2-1.9-1.9-1.92.6-2.4-1.4-1.31.00.1-0.30.2-0.70.61.5
Pavlov. Cond. intertrial magazine entries2.93.88.31.8-2.02.01.7-1.1-2.21.6-2.4-2.4-2.41.0-0.6-1.9-2.12.92.11.8-2.31.8-2.0-1.3
Pavlov. Cond. lever-magazine prob. diff.2.02.67.1-1.71.9-1.7-1.42.71.7-1.31.91.91.9-2.62.21.81.4-1.4-0.4-0.00.20.4-0.3-1.2
Pavlov. Cond. response bias0.91.34.8-0.91.2-1.0-0.82.01.1-0.71.21.21.2-2.21.61.20.7-1.10.10.30.10.7-0.3-1.3
Time in closed arm before self-admin4.14.68.5-2.62.6-2.2-1.92.32.6-1.72.52.52.4-2.32.22.92.9-1.8-1.8-1.61.3-1.10.91.3
Time in closed arm after self-admin0.50.51.10.8-0.60.80.7-0.5-0.70.8-1.0-1.0-1.00.5-0.4-0.4-0.60.90.50.6-0.40.4-0.80.4
Time in open arm before self-admin0.20.20.70.2-0.00.0-0.1-0.70.1-0.1-0.0-0.00.10.7-0.7-0.3-0.1-0.4-0.6-0.50.2-0.80.70.6
Time in open arm after self-admin0.70.82.6-0.40.6-0.6-0.3-0.40.7-0.30.90.90.90.4-0.60.20.4-1.3-1.3-1.41.1-1.51.60.9
Bone: periosteal estimation1.53.18.92.4-2.31.91.8-2.6-1.91.8-1.8-1.8-1.82.4-3.0-1.5-1.8-0.30.80.31.1-0.11.20.9
Bone: periosteal perimeter3.15.211.23.1-2.82.72.6-3.3-2.62.6-2.5-2.5-2.52.9-3.3-2.5-2.30.51.10.60.70.00.90.9
Bone: post-yield work0.40.61.60.7-0.60.60.40.1-0.70.4-0.7-0.7-0.7-0.1-0.0-0.4-1.10.91.11.0-1.31.1-0.9-1.0
Progressive ratio test 1 active lever presses0.80.82.70.4-0.40.50.30.3-0.70.2-0.6-0.6-0.7-0.50.6-0.8-0.71.31.11.3-1.61.3-1.5-1.4
Progressive ratio test 1 breakpoint0.50.51.80.3-0.30.30.10.2-0.4-0.0-0.5-0.5-0.6-0.40.5-0.7-0.51.10.71.0-1.30.9-1.2-1.1
Progressive ratio test 1 inactive lever presses1.92.06.80.5-0.40.80.81.1-0.70.7-0.9-0.9-1.0-1.21.4-0.6-0.81.91.72.0-2.62.1-2.4-2.2
Progressive ratio test 2 active lever presses0.50.61.5-0.40.2-0.3-0.61.0-0.0-0.70.00.00.0-1.11.2-0.00.20.80.71.0-1.21.1-1.1-0.9
Progressive ratio test 2 breakpoint0.70.72.7-0.2-0.00.0-0.41.0-0.2-0.5-0.2-0.2-0.2-1.11.2-0.20.01.11.01.2-1.61.4-1.4-1.1
Progressive ratio test 2 inactive lever presses1.11.34.0-0.70.6-0.6-0.81.80.3-0.90.30.30.3-1.92.00.50.40.90.91.2-1.81.5-1.6-1.3
Incentive Sensitization - Responses0.50.51.5-0.60.4-0.4-0.81.10.3-0.80.30.30.3-1.21.20.40.50.40.50.6-0.90.8-0.7-0.8
Incentive Sensitization - Breakpoint0.50.51.4-0.50.2-0.2-0.51.10.1-0.60.10.10.1-1.21.10.20.30.60.70.8-1.11.1-0.9-0.9
Sum of active levers in priming session hrs 5-60.00.00.1-0.00.2-0.00.10.30.20.10.20.20.2-0.10.30.2-0.4-0.1-0.1-0.1-0.30.0-0.0-0.3
Progressive ratio0.10.10.5-0.40.3-0.2-0.10.70.2-0.00.30.20.3-0.60.60.50.3-0.10.20.2-0.30.4-0.3-0.2
Food seeking constrained by brief footshock1.41.73.81.2-1.51.71.8-1.1-1.51.7-1.5-1.5-1.40.9-0.9-1.9-1.11.11.21.3-0.80.9-0.9-0.8
Seeking ratio, punishment vs. effort0.60.71.80.9-0.91.00.9-0.8-1.00.8-1.0-1.0-1.00.6-0.6-1.3-0.80.90.60.8-0.60.4-0.6-0.7
Retroperitoneal fat weight3.09.715.53.9-3.43.93.9-3.0-3.53.9-3.8-3.8-3.82.5-2.7-3.9-3.52.52.52.5-1.51.6-1.4-0.5
Reaction time number correct1.72.43.9-1.41.3-1.7-1.80.01.5-1.91.61.61.6-0.10.01.01.6-1.9-2.0-1.91.5-2.01.91.8
Reaction time mean minus median0.20.31.50.4-0.70.50.4-0.9-0.50.4-0.4-0.4-0.41.2-0.8-0.2-0.50.60.1-0.40.8-0.20.20.6
Reaction time mean minus median AUC0.60.81.70.7-1.01.21.3-1.1-1.01.3-0.8-0.8-0.81.3-0.8-0.9-0.91.20.50.10.20.1-0.30.5
Reaction time num false alarms0.60.82.90.2-0.2-0.0-0.1-1.10.0-0.10.10.10.11.3-1.20.40.2-0.9-0.8-1.11.7-1.21.31.5
Reaction time num false alarms AUC0.60.93.00.1-0.1-0.3-0.5-1.00.1-0.50.30.30.31.2-1.20.70.3-1.1-0.9-1.21.7-1.31.51.6
Reaction time trials correct on left1.72.43.9-1.41.3-1.7-1.80.01.5-1.91.61.61.6-0.10.01.01.6-1.9-2.0-1.91.5-2.01.91.8
Reaction time trials on left1.82.64.2-1.41.3-1.7-1.90.01.5-1.91.61.61.6-0.10.01.11.6-2.0-2.0-1.91.6-2.02.01.9
Reaction time mean0.10.10.4-0.50.3-0.3-0.30.30.3-0.30.50.50.5-0.10.50.70.40.0-0.1-0.30.4-0.1-0.10.3
Reaction time mean AUC0.10.10.4-0.50.3-0.2-0.30.30.3-0.30.50.50.5-0.20.50.60.40.0-0.2-0.30.2-0.1-0.10.3
Median of all reaction times0.30.40.9-0.80.7-0.6-0.60.80.6-0.50.80.80.8-0.60.90.90.7-0.2-0.3-0.30.2-0.1-0.20.1
Reaction time omissions0.30.51.6-0.60.4-0.8-0.9-0.10.5-0.90.60.60.60.3-0.10.70.3-0.3-0.7-1.00.9-0.80.71.2
Reaction time false alarm rate0.20.31.10.7-0.70.60.5-0.8-0.60.6-0.6-0.6-0.61.0-0.90.1-0.40.20.2-0.10.6-0.00.10.5
Reaction time premature initiation rate0.30.41.4-0.50.4-0.3-0.31.20.4-0.20.50.50.5-1.20.80.60.7-0.80.40.5-0.20.7-0.2-0.8
Reaction time premature initiations0.50.71.7-0.90.8-0.9-0.91.00.9-0.91.01.01.0-1.10.70.81.2-1.3-0.4-0.20.4-0.10.50.0
Std. dev. reaction times0.30.41.40.6-0.90.80.6-1.0-0.80.6-0.6-0.6-0.61.2-0.8-0.5-0.70.70.40.00.70.1-0.10.3
Reaction time trials completed1.82.64.2-1.41.3-1.7-1.90.01.5-1.91.61.61.6-0.10.01.11.6-2.0-2.0-1.91.6-2.02.01.9
Reaction time trials AUC1.42.13.6-1.31.2-1.5-1.6-0.01.3-1.71.51.51.5-0.1-0.10.91.4-1.9-1.8-1.71.5-1.81.91.7
Run reversals in cocaine runway, females1.31.33.2-0.70.8-1.0-1.1-0.41.0-1.10.80.80.80.5-0.70.80.8-1.6-1.7-1.51.4-1.81.51.5
Run reversals in cocaine runway, males0.50.52.10.6-0.90.3-0.0-1.3-0.7-0.2-0.4-0.4-0.41.4-1.4-0.8-0.6-0.10.1-0.20.4-0.30.71.0
Latency to leave start box in cocaine runway0.20.20.60.5-0.40.60.7-0.3-0.40.8-0.5-0.5-0.50.6-0.2-0.3-0.40.50.30.3-0.30.3-0.3-0.0
Latency to leave start box in cocaine runway, F0.20.30.5-0.50.6-0.5-0.40.30.6-0.40.50.50.5-0.00.20.70.7-0.6-0.6-0.60.4-0.50.40.7
Latency to leave start box in cocaine runway, M2.32.23.51.6-1.41.81.9-0.6-1.51.9-1.6-1.6-1.60.7-0.3-1.5-1.71.81.61.6-1.31.5-1.4-1.3
Std. dev. time between licks in bursts1.01.22.3-1.31.2-1.4-1.51.51.1-1.51.11.11.1-1.51.21.51.1-0.9-0.4-0.2-0.10.1-0.0-0.3
Total sessions with >9 infusions1.82.03.31.4-1.41.41.1-0.5-1.51.0-1.6-1.6-1.60.4-0.2-1.6-1.41.81.71.8-1.41.6-1.5-1.4
Short access day 1 total inactive lever presses1.31.52.91.4-1.41.20.9-0.4-1.50.8-1.2-1.2-1.30.4-0.4-1.3-1.61.21.71.5-1.01.6-1.1-1.3
Short access day 10 total inactive lever presses0.50.51.11.0-1.00.80.8-0.8-1.00.8-0.6-0.6-0.60.9-0.9-0.6-0.90.40.80.4-0.50.50.0-0.7
Short access day 1 total infusions2.22.33.81.6-1.51.51.2-0.4-1.71.1-1.8-1.8-1.70.3-0.2-1.4-1.61.91.92.0-1.41.8-1.6-1.8
Short access day 10 total infusions0.91.02.00.6-0.61.11.10.0-0.81.1-1.0-1.0-1.00.00.4-1.2-0.71.41.11.3-1.41.2-1.3-1.0
Short access total infusions3.23.66.41.6-1.51.91.7-0.1-1.81.6-2.0-2.0-2.00.10.3-1.9-1.72.52.32.5-2.32.3-2.4-2.3
Short access day 1 locomotion0.50.51.40.4-0.20.60.50.4-0.40.5-0.7-0.7-0.6-0.50.5-0.6-0.51.10.81.1-1.20.9-1.1-0.8
Short access day 10 total locomotion0.20.21.3-0.10.20.50.70.40.00.7-0.3-0.3-0.2-0.60.5-0.2-0.10.70.20.5-1.20.3-0.7-0.4
Short access total locomotion1.81.94.41.0-0.91.51.4-0.1-1.21.4-1.5-1.5-1.4-0.10.2-1.4-1.21.91.41.8-2.11.5-1.8-1.5
One hour access (0.3 mA shock)0.30.31.2-0.80.7-0.6-0.70.60.6-0.80.50.50.6-0.50.80.41.10.0-0.4-0.20.0-0.1-0.10.4
Compulsive drug intake2.02.04.2-1.51.3-1.8-2.01.01.4-2.01.71.71.8-0.81.01.31.6-1.3-1.1-1.21.2-0.81.11.1
One hour access (shock baseline)0.10.10.40.10.00.40.5-0.1-0.10.5-0.4-0.4-0.4-0.20.2-0.20.10.60.00.4-0.50.1-0.60.0
Social response proportion0.40.51.10.6-0.30.60.90.5-0.41.0-0.4-0.4-0.4-0.20.4-0.1-0.70.90.90.8-0.51.1-1.0-1.0
Social responses0.20.21.60.1-0.0-0.2-0.3-0.30.1-0.30.10.10.10.5-0.60.50.3-0.7-0.4-0.50.8-0.50.71.3
Social time1.41.83.3-1.81.7-1.5-1.51.61.6-1.51.51.51.5-1.61.61.61.5-0.7-1.0-0.7-0.3-0.5-0.00.5
Soleus weight0.10.41.4-0.40.4-0.8-1.20.80.4-1.20.40.40.4-0.40.70.7-0.2-0.00.10.2-0.50.4-0.4-0.9
Bone: stiffness1.52.43.71.6-1.61.91.9-0.7-1.71.9-1.7-1.7-1.70.6-0.8-1.7-1.41.61.81.8-1.41.6-1.3-1.2
Tibialis anterior weight0.51.74.1-1.91.5-1.5-1.51.91.4-1.41.41.41.4-1.22.01.61.80.1-0.4-0.4-0.40.2-0.7-0.4
Time to tail flick, vehicle, before self-admin0.30.31.00.2-0.4-0.1-0.2-0.6-0.2-0.2-0.0-0.0-0.11.0-1.00.2-0.6-0.6-0.2-0.50.7-0.41.00.6
Time to tail flick, vehicle, after self-admin2.22.45.9-0.80.7-1.1-1.0-0.71.1-0.91.31.31.31.3-1.01.21.4-2.0-1.9-2.22.1-2.22.42.3
Time to tail flick, test, before self-admin0.50.53.40.2-0.30.20.1-1.1-0.10.2-0.2-0.2-0.21.2-1.20.00.1-0.4-0.7-0.80.5-1.00.91.8
Time to tail flick, test, after self-admin1.01.11.7-1.01.2-1.1-0.80.61.3-0.71.21.21.1-0.60.61.21.0-1.1-1.3-1.11.2-1.10.90.9
Delta time to tail flick, vehicle, before/after SA0.10.10.8-0.40.4-0.20.10.50.40.10.50.50.5-0.30.60.10.9-0.1-0.2-0.20.0-0.0-0.00.4
Delta time to tail flick, test, before/after SA2.11.92.8-1.41.6-1.7-1.61.41.6-1.61.61.61.6-1.41.31.61.1-1.3-1.1-1.01.2-0.70.70.0
Tibia length0.51.52.81.7-1.71.31.2-1.2-1.61.1-1.3-1.4-1.30.8-1.2-1.6-1.60.71.41.10.41.0-0.3-0.8
Ambulatory time before self-admin0.60.72.5-0.10.30.10.11.00.00.1-0.2-0.2-0.1-1.31.3-0.30.21.10.61.0-1.61.0-1.5-0.9
Ambulatory time after self-admin0.20.30.7-0.80.3-0.6-0.80.60.4-0.80.50.50.6-0.70.40.50.6-0.50.0-0.10.10.20.10.2
Bone: tissue strength0.10.10.20.3-0.40.30.3-0.2-0.40.3-0.2-0.2-0.20.1-0.4-0.2-0.3-0.20.40.30.10.30.20.0
Total heroin consumption0.20.21.4-0.0-0.2-0.0-0.20.3-0.3-0.2-0.2-0.2-0.1-0.10.4-0.2-0.50.40.60.5-0.60.7-0.5-1.2
Bone: trabecular number0.10.20.7-0.10.10.00.3-0.40.20.30.10.20.10.2-0.4-0.20.3-0.5-0.6-0.50.8-0.70.50.6
Bone: trabecular spacing1.01.32.11.2-1.11.11.1-0.5-1.31.1-1.3-1.3-1.30.2-0.2-1.4-1.31.41.41.4-1.41.3-1.0-0.9
Bone: trabecular thickness0.10.10.5-0.30.5-0.3-0.10.40.5-0.10.40.40.4-0.20.20.70.4-0.6-0.4-0.30.3-0.30.20.1
Bone: trabecular tissue density1.01.33.2-1.51.3-1.2-1.21.81.3-1.11.41.41.4-1.01.61.81.3-0.6-0.3-0.50.00.1-0.1-0.5
Water consumed over 24 hours0.60.71.60.7-1.31.00.8-0.8-1.20.8-1.0-1.0-1.00.7-0.8-1.1-1.00.81.10.6-0.10.8-0.3-0.4
Number of responses in last shaping day1.01.13.9-0.91.0-0.7-0.81.90.7-0.80.30.30.3-2.02.00.90.60.50.30.7-1.21.0-1.4-0.8