Hub : Genes

Cenpk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Cenpk 0.09 0.09 8.5e-03 0.08 0.05 0.02 0.05 4.5e-03 1.6e-02 8.8e-02 1.6e-02
2 OFC alternative TSS NM_001399198.1 0.17 0.14 2.4e-03 0.05 -0.01 0.06 -0 2.4e-02 5.4e-01 1.5e-02 3.7e-01
3 OFC alternative TSS XM_008760667.3 0.17 0.14 3.2e-03 0.05 -0.01 0.04 -0.01 2.7e-02 5.9e-01 4.7e-02 4.6e-01
4 OFC alternative TSS XM_008760667.3 0.18 0.14 3.3e-03 0.05 -0.01 0.05 -0.01 2.1e-02 6.0e-01 2.8e-02 4.6e-01
5 IL alternative TSS NM_001399198.1 0.24 0.24 5.1e-03 0.05 0.06 0.03 0.07 2.2e-02 1.6e-02 8.1e-02 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5
Bone: apparent density0.71.11.3-1.01.0-1.1-1.11.2
Area under the delay curve0.60.70.90.7-1.01.01.0-0.1
BMI with tail2.06.57.2-2.32.6-2.6-2.62.7
BMI without tail0.30.61.0-1.00.7-0.6-0.60.9
Body weight1.66.68.12.8-2.52.52.5-2.6
Weight adjusted by age0.30.30.60.3-0.50.50.5-0.8
Bone surface0.00.10.2-0.10.2-0.2-0.20.5
Bone volume0.10.20.5-0.40.4-0.5-0.50.7
Breakpoint value in progressive ratio session2.52.83.9-1.51.6-1.6-1.62.0
Number of licking bursts3.64.24.2-2.12.0-2.1-2.12.0
Context. condit. distance diff. score1.82.12.41.5-1.51.61.6-1.0
Locomotion velocity, session 10.40.40.70.8-0.60.70.7-0.5
Locomotion distance, session 10.70.91.01.0-1.01.01.0-0.7
Locomotion velocity, session 24.04.74.92.2-2.12.12.1-2.2
Locomotion distance, session 20.60.91.21.1-1.00.90.9-0.7
Locomotion velocity, session 34.65.46.62.6-2.32.32.3-2.2
Locomotion distance, session 37.37.98.83.0-2.82.82.8-2.6
Stereotopy head waving bouts, day 30.30.30.60.4-0.50.50.5-0.8
Stereotopy head waving duration, day 30.00.00.0-0.20.2-0.2-0.2-0.1
Locomotion velocity, session 70.10.10.20.4-0.20.10.1-0.4
Locomotion distance, session 70.30.40.60.7-0.60.60.6-0.7
Stereotopy head waving bouts, day 70.10.10.1-0.10.3-0.3-0.3-0.1
Stereotopy head waving duration, day 70.00.10.20.2-0.10.10.1-0.5
Locomotion velocity, session 82.63.13.21.8-1.71.71.7-1.8
Locomotion distance, session 84.16.06.72.6-2.52.52.5-2.0
Degree of sensitization distance3.43.44.1-2.01.9-1.9-1.91.5
Degree of sensitization stereotypy0.10.10.1-0.00.3-0.3-0.30.0
Conditioned locomotion0.10.10.1-0.20.3-0.3-0.30.3
Cocaine response after cond. corrected1.82.02.31.3-1.41.51.5-1.3
Cocaine response after cond. not corrected2.52.83.31.6-1.71.81.8-1.3
Cocaine response before conditioning0.30.40.50.7-0.70.70.7-0.4
Saline control response1.31.72.01.4-1.31.31.3-1.0
Bone: connectivity density0.10.10.1-0.30.3-0.3-0.30.4
Bone: cortical apparent density0.10.20.30.3-0.40.50.5-0.6
Bone: cortical area0.10.10.20.3-0.30.30.3-0.5
Bone: cortical porosity1.82.02.5-1.31.5-1.6-1.60.8
Bone: cortical porosity1.92.12.6-1.31.6-1.6-1.60.9
Bone: cortical thickness0.10.20.60.2-0.20.30.3-0.7
Bone: cortical thickness0.81.01.01.0-1.01.01.0-0.9
Bone: cortical tissue density0.20.20.40.3-0.40.50.5-0.6
Condit. Reinf. active minus inactive responses1.72.02.7-1.61.5-1.5-1.50.8
Condit. Reinf. active-inactive response ratio1.81.92.6-1.61.5-1.4-1.40.9
Condit. Reinf. active responses0.20.30.5-0.70.6-0.6-0.60.1
Condit. Reinf. inactive responses1.21.51.61.3-1.21.21.2-1.1
Incentive salience index mean1.21.52.0-1.41.3-1.3-1.30.8
Condit. Reinf. lever presses0.40.50.6-0.70.7-0.7-0.70.7
Condit. Reinf. active minus inactive responses3.64.45.02.2-2.12.12.1-2.0
Condit. Reinf. active-inactive response ratio2.12.22.81.4-1.41.41.4-1.7
Condit. Reinf. active responses1.21.72.01.4-1.21.31.3-1.3
Condit. Reinf. inactive responses0.10.10.20.4-0.30.40.4-0.2
Condit. Reinf. lever presses1.72.42.51.6-1.51.61.6-1.4
Condit. Reinf. lever reinforcers received1.72.42.81.7-1.51.51.5-1.5
Conditioned reinforcement - actives2.52.63.01.7-1.61.61.6-1.5
Conditioned reinforcement - inactives0.30.30.40.4-0.60.60.6-0.6
Conditioned locomotion0.60.71.11.0-0.80.80.8-0.8
Patch foraging indifference point 0 sec4.57.37.92.3-2.82.82.8-2.7
Patch foraging indifference point AUC0.91.01.5-0.71.0-1.0-1.01.2
Delay disc. indifference point, 0s delay0.10.10.2-0.40.4-0.4-0.40.3
Delay disc. indifference point, 16s delay1.01.01.21.1-1.11.11.1-0.4
Delay disc. indifference point, 2s delay0.10.10.1-0.40.4-0.4-0.4-0.0
Delay disc. indifference point, 24s delay1.01.01.40.9-1.21.21.2-0.1
Delay disc. indifference point, 4s delay0.00.00.0-0.2-0.20.20.2-0.1
Delay disc. indifference point, 8s delay0.40.40.50.4-0.70.70.70.4
Indifference point function ln k4.46.16.72.1-2.52.52.5-2.6
Indifference point function log k4.46.16.72.1-2.52.52.5-2.6
Patch foraging total patch changes 0 sec5.48.79.62.6-3.03.03.0-3.1
Patch foraging total patch changes 12 sec0.00.00.0-0.00.0-0.0-0.00.2
Patch foraging total patch changes 18 sec0.00.00.0-0.1-0.00.10.1-0.2
Patch foraging total patch changes 24 sec0.81.01.10.8-1.01.01.0-1.0
Patch foraging total patch changes 6 sec0.91.31.40.9-1.21.21.2-1.2
Patch foraging time to switch 0 sec6.09.310.6-3.13.0-3.0-3.03.3
Patch foraging water rate 0 sec5.28.49.82.8-2.92.82.8-3.1
Patch foraging water rate 12 sec5.17.89.02.5-2.82.82.8-3.0
Patch foraging water rate 18 sec6.08.18.22.9-2.92.82.8-2.9
Patch foraging water rate 24 sec2.53.54.81.9-1.71.71.7-2.2
Patch foraging water rate 6 sec14.020.420.94.4-4.64.64.6-4.5
Seeking ratio, delayed vs. immediate footshock1.41.61.7-1.21.3-1.3-1.31.2
Distance traveled before self-admin1.81.92.01.3-1.41.41.4-1.4
Distance traveled after self-admin1.51.71.71.2-1.31.31.3-1.3
Extensor digitorum longus weight4.116.017.0-4.04.1-4.1-4.13.7
Bone: elastic displacement1.61.82.0-1.21.4-1.4-1.41.2
Bone: elastic work0.81.01.1-0.91.0-1.1-1.11.1
Bone: endosteal estimation0.20.50.70.7-0.80.80.8-0.4
Bone: endosteal perimeter0.00.00.2-0.1-0.0-0.0-0.00.4
Epididymis fat weight0.00.10.10.10.3-0.3-0.3-0.3
Delta time in closed arm before/after self-admin3.73.66.1-1.81.7-1.7-1.72.5
Delta time in open arm before/after self-admin0.00.00.0-0.0-0.10.10.10.1
Diff in mean of infusions in LGA sessions0.10.20.3-0.40.3-0.4-0.40.5
Delay discount exponential model param0.60.60.9-0.70.9-0.9-0.90.1
Extinction: sum of active levers before priming1.11.12.1-1.10.9-0.9-0.91.4
Active lever presses in extinction session 62.01.92.3-1.11.4-1.4-1.41.5
Bone: final force0.60.91.11.1-1.01.01.0-0.8
Bone: final moment0.81.21.51.2-1.21.11.1-1.0
Food consumed during 24 hour testing period0.91.11.41.0-1.01.01.0-1.2
Glucose1.01.51.9-1.31.3-1.4-1.40.5
Heart weight0.40.60.7-0.70.8-0.9-0.90.6
Delay discount hyperbolic model param0.40.40.6-0.50.8-0.8-0.80.2
Intermittent access intake day 1-15 change0.10.10.2-0.0-0.20.20.2-0.5
Intermittent access intake escalation0.20.20.40.1-0.30.30.3-0.7
Intermittent access intake escalation 20.00.00.0-0.10.1-0.1-0.1-0.1
Intermitt. access day 1 inactive lever presses2.62.83.6-1.91.7-1.7-1.71.5
Intermitt. access day 15 inactive lever presses3.03.33.8-2.01.8-1.8-1.81.8
Intermitt. access escalation Index0.20.20.60.8-0.30.30.3-0.3
Intermittent access day 1 total infusions0.80.91.31.2-0.80.80.8-1.0
Intermittent access day 15 total infusions1.61.82.71.2-1.31.31.3-1.6
Intermittent access terminal intake (last 3 days)0.70.81.00.8-0.80.80.8-1.0
Intermittent access total infusions1.92.12.61.4-1.41.41.4-1.6
Intermittent access day 1 locomotion2.22.32.91.7-1.41.41.4-1.7
Intermittent access day 15 total locomotion1.81.93.11.3-1.31.31.3-1.8
Intermittent access total locomotion4.55.16.52.2-2.22.22.2-2.6
Intermittent access standard deviation0.50.60.7-0.50.9-0.9-0.90.6
Left kidney weight1.02.93.41.8-1.71.71.7-1.6
Right kidney weight0.30.91.41.2-0.90.90.9-0.7
Cocaine induced anxiety0.91.01.31.0-1.11.11.1-0.5
Post-drug Anxiety1.41.61.81.2-1.41.41.4-1.0
Baseline Anxiety0.00.00.0-0.0-0.10.10.1-0.2
Tail length8.525.727.04.7-5.15.25.2-5.1
Length with tail12.144.245.26.7-6.66.66.6-6.7
Length without tail6.915.218.94.3-3.83.73.7-4.0
Times rat made contact with spout0.40.50.6-0.80.7-0.7-0.70.7
Lifetime Intake1.61.82.31.4-1.31.31.3-1.5
Liver weight, left0.40.62.20.6-0.50.50.5-1.5
Liver weight, right0.00.10.2-0.20.3-0.3-0.30.4
Locomotor activity0.40.60.70.8-0.80.80.8-0.4
Locomotor testing distance0.20.30.9-0.60.3-0.3-0.31.0
Locomotor testing rearing0.10.20.5-0.50.3-0.3-0.30.7
Locomotion in novel chamber0.81.01.3-1.11.0-0.9-0.91.1
Locomotion in novel chamber post-restriction0.10.10.4-0.30.1-0.1-0.10.6
Fecal boli incidents, locomotor time 12.22.43.9-1.21.5-1.5-1.52.0
Change in fecal boli incidents, locomotor task0.20.20.3-0.60.5-0.4-0.4-0.3
Time >=10cm from walls, locomotor time 11.71.72.8-1.71.3-1.2-1.21.2
Bouts of movement, locomotor time 10.30.30.5-0.70.4-0.4-0.40.7
Total resting periods, locomotor time 10.10.10.3-0.30.1-0.1-0.10.6
Rest time, locomotor task time 11.71.92.6-1.31.3-1.3-1.31.6
Distance moved, locomotor task time 11.92.13.51.3-1.31.31.3-1.9
Vertical activity count, locomotor time 11.21.32.41.1-1.01.01.0-1.6
Time >=10cm from walls, locomotor time 20.90.91.4-1.20.8-0.9-0.91.1
Bouts of movement, locomotor time 20.20.20.30.5-0.50.40.4-0.2
Total resting periods, locomotor time 20.00.00.00.00.0-0.1-0.10.2
Rest time, locomotor task time 23.74.24.5-2.02.1-2.0-2.02.0
Distance moved, locomotor task time 22.22.62.81.7-1.61.51.5-1.7
Vertical activity count, locomotor time 20.40.41.10.6-0.50.50.5-1.1
Light reinforcement 12.64.75.52.0-2.22.12.1-2.3
Light reinforcement 20.10.10.2-0.30.4-0.4-0.40.3
Bone: marrow area0.20.50.60.7-0.80.80.8-0.3
Bone: maximum diameter0.50.80.9-0.90.9-0.9-0.91.0
Bone: maximum force0.10.20.20.5-0.50.40.4-0.2
Bone: maximum moment0.20.40.50.7-0.70.60.6-0.4
Mean time between licks in bursts0.10.10.2-0.50.3-0.3-0.30.3
Mean num. licks in bursts2.22.72.71.6-1.61.61.6-1.6
Cd content in liver0.50.50.60.8-0.70.70.7-0.7
Co content in liver0.10.20.30.5-0.40.40.4-0.2
Cu content in liver0.20.20.70.4-0.40.40.4-0.8
Fe content in liver1.51.82.41.2-1.31.31.3-1.5
K content in liver3.23.13.92.0-1.91.91.9-1.1
Mg content in liver0.70.71.21.1-0.90.90.9-0.1
Mn content in liver0.30.40.50.7-0.50.50.5-0.6
Na content in liver0.20.20.40.6-0.50.40.4-0.3
Rb content in liver0.70.91.11.0-0.90.90.9-1.1
Se content in liver0.10.10.2-0.40.4-0.4-0.40.2
Sr content in liver2.52.33.4-1.31.4-1.4-1.41.8
Zn content in liver0.10.10.1-0.0-0.30.30.30.2
Bone: minimum diameter2.03.84.21.9-2.02.02.0-1.8
Time in familiar zone, hab. session 14.34.04.72.2-1.91.91.9-2.0
Time in novel zone, hab. session 16.16.06.7-2.62.4-2.4-2.42.4
Total zone transitions, hab. session 10.00.00.10.3-0.20.10.10.0
Total locomotion distance, hab. session 10.10.10.40.6-0.30.30.30.2
Locomotion velocity, hab. session 10.10.10.30.6-0.30.20.20.1
Time in familiar zone, hab. session 21.71.72.21.5-1.31.31.3-1.2
Time in novel zone, hab. session 22.22.22.5-1.61.5-1.5-1.51.3
Total zone transitions, hab. session 20.10.20.30.6-0.40.40.4-0.3
Total locomotion distance, hab. session 20.00.10.30.20.0-0.0-0.00.5
Locomotion velocity, hab. session 20.10.10.30.5-0.30.30.30.1
Novel to familiar place preference ratio2.32.42.6-1.61.5-1.6-1.61.5
Novelty place preference1.81.82.0-1.41.3-1.4-1.41.2
Time in novel zone, NPP test1.92.02.1-1.41.4-1.4-1.41.3
Total zone transitions, NPP test1.62.32.71.6-1.51.51.5-1.4
Total locomotion distance, NPP test0.10.20.50.7-0.40.40.4-0.1
Locomotion velocity, NPP test0.71.01.41.2-1.01.01.0-0.7
Intraocular pressure3.65.05.6-2.42.4-2.4-2.41.7
Delta distance traveled before/after self-admin0.50.50.70.8-0.70.70.7-0.6
Delta ambulatory time before/after self-admin0.50.60.80.9-0.80.70.7-0.6
Parametrial fat weight0.00.00.1-0.20.2-0.2-0.2-0.2
Pavlov. Cond. lever latency0.10.10.1-0.30.3-0.3-0.30.1
Pavlov. Cond. magazine entry latency2.53.23.71.8-1.91.91.9-1.3
Pavlov. Cond. change in total contacts3.53.74.21.9-2.02.02.0-1.7
Pavlov. Cond. index score0.70.91.10.9-1.01.01.0-0.6
Pavlov. Cond. latency score0.30.30.40.6-0.70.60.6-0.2
Pavlov. Cond. lever contacts0.60.70.80.8-0.90.90.9-0.5
Pavlov. Cond. magazine entry number2.63.33.9-1.92.0-1.9-1.91.2
Pavlov. Cond. intertrial magazine entries5.66.87.4-2.72.7-2.7-2.72.2
Pavlov. Cond. lever-magazine prob. diff.0.91.11.41.0-1.21.21.2-0.7
Pavlov. Cond. response bias2.53.03.41.8-1.81.81.8-1.3
Pavlov. Cond. lever latency1.92.52.7-1.61.6-1.6-1.61.4
Pavlov. Cond. magazine entry latency1.01.21.41.1-1.21.21.2-0.7
Pavlov. Cond. change in total contacts5.27.17.72.6-2.82.82.8-2.4
Pavlov. Cond. index score2.63.43.81.8-1.92.02.0-1.5
Pavlov. Cond. latency score2.73.43.91.8-1.92.02.0-1.5
Pavlov. Cond. lever contacts2.02.72.81.7-1.71.71.7-1.5
Pavlov. Cond. magazine entry number1.92.32.6-1.61.6-1.6-1.61.1
Pavlov. Cond. intertrial magazine entries0.10.10.30.3-0.10.10.1-0.5
Pavlov. Cond. lever-magazine prob. diff.2.83.64.01.9-2.02.02.0-1.5
Pavlov. Cond. response bias1.62.22.41.5-1.51.51.5-1.3
Time in closed arm before self-admin0.00.10.10.3-0.20.20.2-0.2
Time in closed arm after self-admin0.60.60.8-0.30.8-0.8-0.80.9
Time in open arm before self-admin0.00.00.10.1-0.20.20.2-0.1
Time in open arm after self-admin0.20.30.5-0.70.4-0.4-0.40.5
Bone: periosteal estimation0.20.30.40.5-0.60.60.6-0.4
Bone: periosteal perimeter0.00.10.10.2-0.30.30.3-0.0
Bone: post-yield work0.00.00.0-0.0-0.0-0.0-0.0-0.2
Progressive ratio test 1 active lever presses0.80.91.11.0-0.90.90.9-1.1
Progressive ratio test 1 breakpoint1.01.01.31.1-1.01.01.0-1.1
Progressive ratio test 1 inactive lever presses0.50.50.60.5-0.70.70.7-0.8
Progressive ratio test 2 active lever presses0.20.20.30.5-0.40.40.4-0.6
Progressive ratio test 2 breakpoint0.10.10.20.4-0.30.30.3-0.5
Progressive ratio test 2 inactive lever presses0.10.10.30.3-0.30.30.3-0.6
Incentive Sensitization - Responses0.60.60.70.7-0.80.80.8-0.7
Incentive Sensitization - Breakpoint0.30.40.40.5-0.60.60.6-0.6
Sum of active levers in priming session hrs 5-61.01.01.3-0.81.1-1.1-1.10.8
Progressive ratio0.00.00.0-0.1-0.00.00.00.2
Food seeking constrained by brief footshock2.12.62.81.6-1.71.71.7-1.5
Seeking ratio, punishment vs. effort0.50.70.90.8-0.80.80.8-1.0
Retroperitoneal fat weight0.72.33.0-1.31.7-1.7-1.71.0
Reaction time number correct8.712.613.33.6-3.53.53.5-3.5
Reaction time mean minus median0.10.10.20.4-0.20.30.3-0.2
Reaction time mean minus median AUC0.30.40.60.8-0.50.50.5-0.7
Reaction time num false alarms0.81.01.2-1.11.0-1.0-1.00.9
Reaction time num false alarms AUC1.31.82.0-1.41.4-1.4-1.41.2
Reaction time trials correct on left8.712.613.33.6-3.53.53.5-3.5
Reaction time trials on left8.912.813.43.7-3.53.53.5-3.6
Reaction time mean1.41.92.1-1.41.4-1.4-1.41.4
Reaction time mean AUC1.21.61.8-1.21.3-1.3-1.31.3
Median of all reaction times2.53.43.5-1.81.9-1.8-1.81.8
Reaction time omissions0.10.10.50.3-0.20.20.2-0.7
Reaction time false alarm rate6.49.09.6-3.13.0-3.0-3.02.9
Reaction time premature initiation rate4.05.35.62.3-2.42.42.4-2.1
Reaction time premature initiations11.416.116.84.1-4.04.04.0-3.8
Std. dev. reaction times0.10.10.2-0.20.4-0.4-0.40.2
Reaction time trials completed8.912.813.43.7-3.53.53.5-3.6
Reaction time trials AUC8.011.612.03.5-3.43.43.4-3.4
Run reversals in cocaine runway, females0.40.40.6-0.70.6-0.6-0.60.8
Run reversals in cocaine runway, males0.10.10.30.4-0.0-0.0-0.00.5
Latency to leave start box in cocaine runway2.42.63.2-1.51.6-1.6-1.61.8
Latency to leave start box in cocaine runway, F0.40.40.6-0.60.6-0.6-0.60.7
Latency to leave start box in cocaine runway, M2.62.52.9-1.41.6-1.6-1.61.7
Std. dev. time between licks in bursts1.01.21.4-0.91.1-1.1-1.11.2
Total sessions with >9 infusions0.70.71.61.2-0.70.70.7-0.8
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.20.20.2-0.3
Short access day 10 total inactive lever presses0.40.40.7-0.70.5-0.5-0.50.9
Short access day 1 total infusions1.01.11.41.0-1.01.01.0-1.2
Short access day 10 total infusions1.11.21.61.2-1.01.01.0-1.2
Short access total infusions1.51.72.11.4-1.21.21.2-1.4
Short access day 1 locomotion0.30.30.60.8-0.30.30.3-0.7
Short access day 10 total locomotion0.00.00.00.00.1-0.1-0.1-0.2
Short access total locomotion1.51.62.71.5-1.01.01.0-1.6
One hour access (0.3 mA shock)0.81.01.61.0-0.90.90.9-1.2
Compulsive drug intake0.20.20.2-0.40.4-0.4-0.40.3
One hour access (shock baseline)1.92.22.61.6-1.41.41.4-1.6
Social response proportion0.10.10.1-0.30.1-0.2-0.20.3
Social responses1.72.22.81.5-1.71.61.6-0.9
Social time0.00.00.0-0.2-0.00.10.1-0.1
Soleus weight0.20.70.9-0.90.9-0.9-0.90.3
Bone: stiffness0.30.50.70.8-0.80.80.8-0.4
Tibialis anterior weight2.48.28.5-2.92.9-2.9-2.92.7
Time to tail flick, vehicle, before self-admin5.05.15.32.3-2.32.32.3-2.2
Time to tail flick, vehicle, after self-admin1.92.02.41.3-1.61.51.5-1.1
Time to tail flick, test, before self-admin0.10.10.20.2-0.40.30.3-0.4
Time to tail flick, test, after self-admin0.80.91.2-0.81.1-1.1-1.10.3
Delta time to tail flick, vehicle, before/after SA1.21.21.7-1.21.0-1.0-1.01.3
Delta time to tail flick, test, before/after SA0.10.10.2-0.20.4-0.4-0.40.2
Tibia length6.016.919.64.1-4.04.04.0-4.4
Ambulatory time before self-admin0.70.70.80.7-0.80.90.9-0.8
Ambulatory time after self-admin1.01.11.21.1-1.11.11.1-0.9
Bone: tissue strength1.11.11.2-1.01.1-1.1-1.10.9
Total heroin consumption1.51.82.2-1.21.4-1.5-1.51.1
Bone: trabecular number0.00.00.1-0.10.1-0.2-0.20.3
Bone: trabecular spacing0.10.20.2-0.40.5-0.5-0.5-0.3
Bone: trabecular thickness0.91.12.0-1.10.9-0.9-0.91.4
Bone: trabecular tissue density2.33.23.3-1.81.8-1.8-1.81.7
Water consumed over 24 hours0.60.80.8-0.90.9-0.9-0.90.8
Number of responses in last shaping day0.50.50.6-0.60.8-0.8-0.80.6