Hub : Genes

Celsr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Celsr1 0.22 0.15 2.6e-04 0.04 0.04 0.02 0.04 3.4e-03 5.2e-03 3.4e-02 4.7e-03
2 PL mRNA stability Celsr1 0.07 0.04 2.7e-07 0.04 0.06 0.05 0.05 4.7e-05 7.8e-07 1.7e-06 2.1e-06
3 IL mRNA stability Celsr1 0.13 0.09 5.6e-03 0.09 0.09 0.05 0.04 3.3e-03 3.3e-03 2.9e-02 4.7e-02
4 Adipose mRNA stability Celsr1 0.12 0.06 9.9e-15 0.1 0.1 0.09 0.1 3.2e-11 3.5e-11 1.2e-10 7.9e-11
5 NAcc gene expression Celsr1 0.07 0.04 8.3e-09 0.07 0.06 0.06 0.06 8.4e-11 4.3e-09 6.7e-10 6.0e-10
6 IC gene expression Celsr1 0.19 0.1 1.4e-06 0.11 0.08 0.14 0.09 1.9e-05 3.1e-04 1.7e-06 1.1e-04
7 NAcc mRNA stability Celsr1 0.04 0.03 1.6e-07 0.05 0.04 0.04 0.04 5.7e-08 3.9e-07 1.7e-07 2.9e-06
8 pVTA mRNA stability Celsr1 0.03 0.02 4.3e-03 0.02 0.01 -0 0 1.5e-02 8.4e-02 6.2e-01 1.9e-01
9 Brain mRNA stability Celsr1 0.22 0.09 0.0e+00 0.2 0.21 0.21 0.2 1.6e-18 1.3e-19 3.2e-19 8.8e-19
10 RMTg mRNA stability Celsr1 0.25 0.19 2.4e-03 0.13 0.06 0.12 -0 2.9e-04 8.9e-03 6.1e-04 4.1e-01
11 LHb gene expression Celsr1 0.24 0.14 5.8e-04 0.05 0.07 0.08 0.08 3.1e-02 9.1e-03 5.8e-03 6.4e-03
12 pVTA gene expression Celsr1 0.19 0.1 3.3e-07 0.05 0.07 0.06 0.05 1.4e-04 1.1e-06 2.5e-05 6.4e-05
13 Brain gene expression Celsr1 0.21 0.1 8.1e-15 0.1 0.15 0.17 0.1 1.8e-09 5.1e-14 1.2e-15 6.0e-10
14 PL gene expression Celsr1 0.04 0.02 2.4e-03 0.01 0.02 0.01 0.01 7.8e-03 2.9e-03 1.6e-02 1.1e-02
15 BLA gene expression Celsr1 0.14 0.09 4.4e-04 0.04 0.04 0 0.03 2.8e-03 6.1e-03 1.9e-01 1.4e-02
16 IL gene expression Celsr1 0.31 0.18 1.2e-04 0.18 0.18 0.14 0.16 3.8e-05 5.2e-05 2.6e-04 9.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.40.61.70.81.10.80.90.90.90.91.20.91.30.6-0.00.30.1-0.10.4
Area under the delay curve2.73.15.32.32.12.32.32.12.01.82.01.71.41.51.71.60.91.2-0.0
BMI with tail2.37.810.6-3.0-2.7-2.6-3.1-2.8-3.3-3.3-3.0-3.0-2.6-3.0-2.2-2.8-2.6-1.6-2.7
BMI without tail0.51.54.1-1.1-1.4-1.5-2.0-1.7-1.5-1.4-1.0-0.8-0.6-1.3-0.7-1.4-0.8-0.4-0.5
Body weight1.46.011.4-2.8-3.3-2.8-3.4-2.8-2.9-3.2-2.7-2.4-2.6-2.4-0.8-1.8-1.1-0.4-1.1
Weight adjusted by age1.31.94.5-1.0-1.5-1.7-2.0-2.1-1.6-1.5-1.2-1.1-0.7-1.4-1.0-1.6-0.7-1.2-0.3
Bone surface0.10.31.00.70.70.50.40.50.60.50.60.71.00.10.20.10.3-0.20.4
Bone volume0.20.40.80.90.90.70.60.70.80.70.80.80.90.40.40.40.40.10.4
Breakpoint value in progressive ratio session0.81.03.3-0.9-0.0-0.7-0.3-0.5-0.8-0.3-0.4-0.9-0.3-0.7-1.8-1.3-1.7-1.6-1.2
Number of licking bursts0.61.03.30.50.20.50.50.50.80.60.61.10.51.01.51.11.41.81.3
Context. condit. distance diff. score1.01.22.9-1.3-1.0-1.0-0.6-0.8-0.9-1.5-1.7-1.7-1.7-1.0-1.1-0.7-0.7-0.5-0.3
Locomotion velocity, session 10.60.72.3-0.8-1.5-1.4-1.0-1.3-0.6-0.7-0.4-0.3-0.6-0.40.2-0.60.60.80.7
Locomotion distance, session 10.50.61.60.80.20.40.40.40.80.70.70.80.50.81.00.71.31.11.1
Locomotion velocity, session 21.82.16.0-1.7-2.5-2.0-1.9-1.9-1.5-1.6-1.5-0.9-1.7-1.10.3-0.80.20.6-0.1
Locomotion distance, session 20.10.10.50.40.50.30.10.40.10.50.60.10.3-0.1-0.1-0.1-0.3-0.4-0.7
Locomotion velocity, session 31.51.74.7-1.0-1.9-1.2-0.7-1.0-0.4-0.9-1.4-0.3-1.8-0.11.40.41.72.21.9
Locomotion distance, session 30.90.94.00.2-0.40.10.30.30.60.40.40.90.11.01.61.11.62.01.3
Stereotopy head waving bouts, day 30.80.93.2-0.4-0.8-0.8-0.8-0.7-0.6-1.3-1.6-1.2-1.8-1.2-0.1-0.7-0.2-0.8-0.1
Stereotopy head waving duration, day 32.22.77.0-1.0-1.4-1.5-1.5-1.5-1.3-2.2-2.4-2.1-2.6-2.0-0.7-1.4-0.7-1.5-0.5
Locomotion velocity, session 70.91.02.9-0.7-1.3-0.7-1.0-0.6-0.7-1.3-1.6-0.7-1.7-0.60.90.30.71.10.6
Locomotion distance, session 70.10.20.8-0.6-0.6-0.1-0.30.2-0.2-0.1-0.40.0-0.10.30.40.60.50.90.3
Stereotopy head waving bouts, day 70.80.93.3-0.9-1.2-1.0-0.9-1.0-0.7-1.3-1.3-1.0-1.8-0.80.1-0.40.20.40.5
Stereotopy head waving duration, day 70.30.41.8-0.5-0.7-0.5-0.5-0.6-0.4-1.0-1.0-0.7-1.3-0.50.2-0.10.20.40.4
Locomotion velocity, session 84.75.68.0-2.7-2.6-2.8-2.5-2.6-2.5-2.6-2.5-2.7-2.8-2.5-1.9-2.3-1.6-1.2-1.4
Locomotion distance, session 80.30.51.4-1.0-1.0-0.8-0.6-0.6-0.6-0.8-0.9-0.9-1.2-0.5-0.5-0.4-0.20.2-0.0
Degree of sensitization distance1.51.63.3-1.4-0.8-1.0-1.0-1.0-1.3-1.0-1.1-1.4-0.8-1.3-1.8-1.3-1.7-1.5-1.4
Degree of sensitization stereotypy0.50.51.3-0.8-0.9-0.9-0.8-0.9-0.6-0.9-0.7-0.7-1.2-0.7-0.2-0.5-0.10.20.4
Conditioned locomotion0.10.10.2-0.2-0.3-0.2-0.4-0.2-0.4-0.5-0.2-0.3-0.2-0.2-0.1-0.1-0.1-0.3-0.2
Cocaine response after cond. corrected0.20.20.7-0.7-0.8-0.5-0.1-0.30.1-0.3-0.00.30.70.30.30.10.50.50.6
Cocaine response after cond. not corrected0.40.51.2-0.4-0.7-0.00.30.20.5-0.00.20.70.80.80.90.71.01.11.0
Cocaine response before conditioning0.50.61.00.70.50.80.80.90.80.70.60.80.41.00.80.90.90.80.6
Saline control response0.20.31.5-0.7-0.3-0.5-0.4-0.4-0.30.30.80.10.80.4-1.2-0.5-0.5-0.20.7
Bone: connectivity density0.30.40.90.70.60.60.50.60.70.70.70.81.00.50.40.40.50.30.9
Bone: cortical apparent density0.91.22.31.51.51.41.21.21.21.50.91.10.91.20.91.10.60.20.3
Bone: cortical area2.03.15.0-1.9-1.7-2.2-2.1-2.2-2.0-1.6-1.5-1.6-1.3-1.7-1.7-2.0-1.5-1.3-1.1
Bone: cortical porosity1.41.53.3-1.5-1.1-1.6-1.1-1.6-1.4-0.8-0.3-0.9-0.4-1.1-1.8-1.6-1.5-1.1-0.9
Bone: cortical porosity1.71.83.1-1.5-1.1-1.6-1.5-1.7-1.6-1.0-0.5-1.0-0.6-1.2-1.8-1.7-1.5-1.1-1.0
Bone: cortical thickness0.30.51.4-0.5-0.1-0.7-0.7-0.7-0.7-0.1-0.2-0.5-0.1-0.6-1.1-0.9-1.1-1.2-0.9
Bone: cortical thickness3.23.86.2-1.7-1.2-2.0-1.9-2.1-2.1-1.7-1.3-2.0-1.3-2.0-2.5-2.4-2.3-2.2-2.0
Bone: cortical tissue density0.70.91.81.31.31.21.01.11.11.30.80.90.81.00.81.00.50.20.3
Condit. Reinf. active minus inactive responses0.30.31.20.50.50.20.60.20.41.10.80.81.10.70.20.20.20.50.2
Condit. Reinf. active-inactive response ratio0.80.92.41.21.30.91.20.91.01.50.71.01.31.00.50.70.40.30.1
Condit. Reinf. active responses1.21.52.31.00.70.91.10.91.21.41.31.51.51.51.21.21.11.51.2
Condit. Reinf. inactive responses0.91.23.10.40.00.80.70.70.90.51.01.20.71.21.31.31.31.81.6
Incentive salience index mean0.40.41.9-0.2-0.6-0.6-0.2-0.7-0.10.40.50.70.90.60.50.10.61.41.0
Condit. Reinf. lever presses0.91.34.2-1.1-1.9-1.4-1.3-1.5-0.9-0.9-0.10.20.10.30.5-0.10.82.01.6
Condit. Reinf. active minus inactive responses0.71.02.2-0.8-0.6-1.1-0.8-1.3-0.8-0.2-0.5-0.6-0.4-1.2-1.4-1.4-1.1-1.5-0.7
Condit. Reinf. active-inactive response ratio0.20.21.0-0.2-0.2-0.4-0.3-0.6-0.20.00.0-0.10.2-0.6-0.7-0.6-0.4-1.0-0.0
Condit. Reinf. active responses2.02.74.1-1.6-1.4-1.8-1.7-2.0-1.7-1.2-1.4-1.5-1.2-1.9-1.9-2.0-1.7-1.8-1.2
Condit. Reinf. inactive responses2.73.44.4-2.0-1.9-2.0-2.1-2.0-2.1-2.0-2.0-2.0-1.9-2.0-1.6-1.9-1.6-1.1-1.3
Condit. Reinf. lever presses0.81.01.7-0.9-1.0-1.0-1.1-1.0-1.1-1.3-1.2-1.1-1.1-1.3-0.7-0.9-0.8-0.8-0.9
Condit. Reinf. lever reinforcers received1.41.93.0-1.4-1.1-1.5-1.4-1.6-1.4-0.9-0.9-1.1-0.9-1.7-1.6-1.7-1.5-1.7-1.0
Conditioned reinforcement - actives0.10.10.8-0.7-0.3-0.30.00.1-0.20.30.3-0.10.40.2-0.9-0.2-0.20.00.4
Conditioned reinforcement - inactives0.30.52.4-1.3-0.5-0.6-0.6-0.3-0.80.0-0.1-0.6-0.1-0.3-1.5-0.9-0.8-0.40.1
Conditioned locomotion0.60.83.0-1.6-1.7-1.2-1.0-0.9-0.9-0.9-0.8-0.6-0.5-0.4-0.3-0.30.10.40.3
Patch foraging indifference point 0 sec0.10.10.9-0.10.00.1-0.1-0.20.10.20.40.51.00.20.0-0.1-0.10.3-0.2
Patch foraging indifference point AUC0.40.51.70.70.50.70.60.70.50.40.90.80.30.71.00.80.61.30.4
Delay disc. indifference point, 0s delay0.00.00.1-0.0-0.2-0.00.20.2-0.1-0.30.1-0.2-0.0-0.10.2-0.0-0.10.1-0.3
Delay disc. indifference point, 16s delay3.03.35.72.42.22.32.12.12.02.12.01.81.81.41.51.61.00.40.1
Delay disc. indifference point, 2s delay0.40.51.01.01.00.90.70.80.60.80.90.60.60.50.40.50.10.6-0.4
Delay disc. indifference point, 24s delay0.10.21.10.10.0-0.2-0.1-0.4-0.10.00.3-0.10.0-0.3-0.2-0.6-0.6-0.4-1.1
Delay disc. indifference point, 4s delay4.14.38.93.02.73.02.72.72.31.81.91.71.41.72.02.00.91.1-0.3
Delay disc. indifference point, 8s delay2.53.05.62.12.12.32.42.12.01.71.71.51.21.51.61.60.81.2-0.2
Indifference point function ln k1.42.44.8-2.2-2.2-2.1-1.9-2.1-1.7-1.7-1.6-1.5-0.8-1.1-1.4-1.4-0.6-0.50.0
Indifference point function log k1.42.44.8-2.2-2.2-2.1-1.9-2.1-1.7-1.7-1.6-1.5-0.8-1.1-1.4-1.4-0.6-0.50.0
Patch foraging total patch changes 0 sec0.10.21.10.20.30.50.20.20.40.40.60.71.10.40.30.30.20.4-0.1
Patch foraging total patch changes 12 sec0.00.00.20.00.00.1-0.1-0.1-0.1-0.3-0.10.0-0.5-0.30.3-0.1-0.00.4-0.1
Patch foraging total patch changes 18 sec0.50.81.60.80.60.60.50.40.81.01.01.30.90.81.10.81.01.10.9
Patch foraging total patch changes 24 sec0.20.31.30.10.00.60.40.40.4-0.10.30.40.00.61.00.80.71.10.4
Patch foraging total patch changes 6 sec0.50.71.50.90.91.20.80.80.80.51.11.01.20.61.00.70.41.0-0.2
Patch foraging time to switch 0 sec0.20.31.30.90.90.50.40.50.30.3-0.2-0.2-0.8-0.5-0.0-0.1-0.3-1.2-0.6
Patch foraging water rate 0 sec0.30.61.2-0.9-0.9-1.0-1.0-1.1-1.0-0.8-0.5-0.5-0.1-0.6-0.6-0.7-0.6-0.0-0.4
Patch foraging water rate 12 sec0.20.51.5-1.1-1.2-0.7-0.9-1.0-0.5-0.20.30.40.90.40.10.20.50.70.8
Patch foraging water rate 18 sec0.20.30.7-0.5-0.7-0.8-0.5-0.8-0.40.00.70.40.70.1-0.1-0.30.20.20.7
Patch foraging water rate 24 sec0.50.71.4-1.2-0.9-1.1-1.0-1.0-1.0-0.4-0.4-0.7-0.2-0.5-1.1-0.9-0.8-0.5-0.3
Patch foraging water rate 6 sec0.40.62.0-0.1-0.3-0.1-0.2-0.10.30.70.91.00.71.00.90.71.21.01.4
Seeking ratio, delayed vs. immediate footshock1.01.22.21.31.41.31.51.41.11.11.31.01.40.90.50.90.30.10.2
Distance traveled before self-admin0.20.31.8-0.2-0.40.00.10.10.30.30.30.40.10.60.50.60.90.91.3
Distance traveled after self-admin0.50.61.2-1.0-0.8-1.0-1.1-0.9-1.0-0.4-0.3-0.6-0.3-0.6-1.1-0.9-0.6-0.60.1
Extensor digitorum longus weight0.31.11.9-1.3-1.4-1.1-1.2-1.1-1.1-1.4-1.3-1.2-1.1-1.2-0.6-0.7-0.4-0.50.0
Bone: elastic displacement0.20.30.8-0.8-0.9-0.8-0.8-0.8-0.6-0.10.1-0.1-0.00.1-0.1-0.20.10.60.5
Bone: elastic work3.64.76.9-2.4-2.1-2.5-2.6-2.6-2.5-2.0-1.9-2.1-2.2-2.3-2.1-2.3-1.7-1.2-1.3
Bone: endosteal estimation1.83.96.2-2.2-2.3-2.3-2.2-2.1-2.1-2.5-2.4-2.2-2.1-2.1-1.3-1.9-1.1-0.6-0.9
Bone: endosteal perimeter2.45.29.0-2.8-2.9-3.0-2.8-3.0-2.6-2.6-2.5-2.1-2.0-2.1-1.4-2.2-1.1-0.3-0.7
Epididymis fat weight0.72.33.7-1.9-1.2-1.2-1.9-1.3-1.9-1.2-1.1-1.4-1.2-1.5-1.6-1.3-1.8-1.5-1.7
Delta time in closed arm before/after self-admin0.20.20.8-0.10.2-0.2-0.3-0.3-0.40.20.2-0.10.0-0.4-0.8-0.6-0.7-0.9-0.6
Delta time in open arm before/after self-admin0.90.93.30.2-0.40.40.10.20.60.10.00.5-0.10.91.41.31.81.71.8
Diff in mean of infusions in LGA sessions1.62.05.0-1.7-0.9-1.6-1.0-1.5-1.4-0.6-0.5-1.20.1-1.0-2.2-1.9-1.9-1.7-1.3
Delay discount exponential model param2.93.25.4-2.3-2.1-2.3-2.3-2.1-2.0-1.9-2.0-1.7-1.3-1.6-1.7-1.6-0.9-1.20.0
Extinction: sum of active levers before priming0.60.62.5-0.90.1-0.2-0.0-0.1-0.6-0.20.1-0.7-0.2-0.7-1.6-1.0-1.5-0.8-1.1
Active lever presses in extinction session 61.51.42.4-1.4-1.1-1.3-1.0-1.0-1.3-1.4-1.4-1.2-0.8-1.2-0.9-1.3-1.2-0.9-1.5
Bone: final force1.82.84.6-1.5-0.8-1.3-1.5-1.4-1.7-1.6-1.0-1.8-1.2-2.0-2.1-2.0-2.1-2.0-2.0
Bone: final moment2.33.75.8-1.6-0.9-1.5-1.7-1.6-2.0-1.8-1.1-2.0-1.4-2.3-2.4-2.2-2.4-2.4-2.3
Food consumed during 24 hour testing period4.05.610.8-2.4-2.7-3.3-2.9-3.1-2.6-2.4-2.2-2.0-2.2-2.4-1.9-2.7-1.5-0.6-0.8
Glucose0.10.20.6-0.5-0.2-0.70.0-0.8-0.20.70.80.30.40.1-0.6-0.6-0.30.00.3
Heart weight2.13.25.2-1.5-1.2-1.3-1.8-1.4-1.9-2.3-2.3-2.3-1.9-2.3-1.6-1.7-1.8-1.4-1.6
Delay discount hyperbolic model param3.13.45.7-2.4-2.1-2.4-2.4-2.2-2.1-1.9-2.0-1.8-1.4-1.6-1.8-1.7-1.0-1.3-0.0
Intermittent access intake day 1-15 change0.91.95.7-1.8-1.3-1.8-1.8-1.7-1.6-0.3-0.5-0.80.2-0.9-2.4-1.8-1.2-1.10.2
Intermittent access intake escalation0.40.82.9-1.2-0.9-1.2-1.2-1.1-1.0-0.0-0.1-0.30.5-0.4-1.7-1.1-0.6-0.40.6
Intermittent access intake escalation 21.11.35.7-1.1-0.4-1.2-1.3-1.2-1.20.50.5-0.20.7-0.7-2.4-1.6-1.2-1.20.1
Intermitt. access day 1 inactive lever presses0.20.81.7-0.8-0.1-0.5-0.7-0.6-0.9-0.2-0.6-0.8-0.9-0.8-1.2-1.1-1.3-1.3-1.1
Intermitt. access day 15 inactive lever presses1.32.65.6-2.1-1.4-2.0-1.8-1.8-1.9-1.0-0.9-1.4-0.2-1.3-2.4-2.1-1.8-1.5-0.9
Intermitt. access escalation Index0.20.32.00.20.50.40.50.40.30.50.50.31.40.6-0.40.2-0.0-0.10.2
Intermittent access day 1 total infusions0.61.03.7-1.9-1.9-1.4-0.7-0.6-0.8-0.8-1.1-0.7-0.8-0.0-0.0-0.10.51.10.9
Intermittent access day 15 total infusions0.91.34.6-2.1-1.9-1.8-1.1-1.0-1.2-0.4-0.6-0.60.2-0.0-1.2-0.60.20.71.5
Intermittent access terminal intake (last 3 days)1.92.68.2-2.9-2.5-2.6-1.9-1.8-1.9-0.8-1.0-1.1-0.4-0.7-1.8-1.4-0.40.00.9
Intermittent access total infusions1.41.76.6-2.6-2.1-2.1-1.4-1.3-1.4-0.7-0.9-1.0-0.6-0.4-1.3-0.9-0.20.20.9
Intermittent access day 1 locomotion0.50.61.7-0.8-1.0-0.30.30.20.30.1-0.30.30.20.81.00.91.21.31.2
Intermittent access day 15 total locomotion0.91.65.5-2.4-2.3-1.7-1.2-1.3-1.2-1.1-1.5-1.0-0.9-0.2-0.5-0.50.10.70.7
Intermittent access total locomotion1.21.45.2-2.3-2.1-1.7-1.2-1.3-1.2-0.9-1.3-1.0-1.2-0.5-0.7-0.5-0.00.20.6
Intermittent access standard deviation1.32.65.6-2.4-1.6-2.0-2.0-1.9-2.0-0.9-1.3-1.5-1.1-1.3-2.1-1.8-1.4-0.8-0.6
Left kidney weight9.946.369.0-7.7-7.6-7.2-7.7-7.4-7.6-8.3-7.8-7.7-7.9-7.1-4.8-5.9-4.3-3.1-3.3
Right kidney weight10.849.169.5-7.6-7.2-7.0-8.0-7.3-7.8-8.3-7.9-8.0-8.3-7.5-5.3-6.2-5.1-3.9-4.2
Cocaine induced anxiety1.01.42.9-0.8-0.4-0.9-0.9-0.9-1.1-0.9-0.8-1.2-1.1-1.4-1.5-1.6-1.7-1.5-1.6
Post-drug Anxiety0.50.62.3-0.00.70.30.20.2-0.10.20.2-0.30.0-0.5-1.2-0.8-1.5-1.2-1.4
Baseline Anxiety1.11.22.00.50.61.11.11.21.11.01.01.11.41.41.01.31.11.31.1
Tail length0.62.57.31.0-0.00.10.20.21.11.31.72.01.61.71.91.42.32.22.7
Length with tail0.21.13.4-1.1-1.9-1.4-1.6-1.3-0.8-0.7-0.4-0.1-0.6-0.20.80.11.01.11.5
Length without tail1.34.37.0-2.6-2.3-2.2-2.4-2.0-2.6-2.2-1.9-2.2-1.9-2.1-1.6-1.8-1.8-1.1-1.6
Times rat made contact with spout0.60.62.8-0.5-1.0-0.6-0.8-0.7-0.3-1.0-1.0-0.2-1.0-0.50.60.10.71.70.7
Lifetime Intake1.41.76.1-2.5-2.1-2.1-1.3-1.3-1.4-0.7-1.0-1.0-0.9-0.5-1.2-0.9-0.20.41.0
Liver weight, left0.91.54.5-1.9-2.1-1.3-1.2-1.3-1.2-1.8-1.5-1.1-1.2-0.8-0.3-0.30.10.30.5
Liver weight, right0.61.13.1-1.0-1.8-0.9-0.9-0.7-0.4-0.9-0.9-0.1-0.90.31.20.71.41.51.8
Locomotor activity2.03.17.7-2.1-2.8-2.4-2.1-2.4-1.8-2.2-2.4-1.4-1.7-1.40.1-1.10.10.20.0
Locomotor testing distance0.10.30.9-0.6-1.0-0.7-0.5-0.7-0.4-0.7-0.7-0.2-0.1-0.30.4-0.20.40.10.2
Locomotor testing rearing0.40.82.0-1.0-1.4-1.2-0.9-1.0-0.8-1.2-1.1-0.7-1.1-0.7-0.0-0.40.40.40.6
Locomotion in novel chamber1.72.27.11.1-0.20.70.50.71.20.00.41.30.91.42.71.82.62.31.9
Locomotion in novel chamber post-restriction0.10.20.70.40.50.80.80.80.4-0.20.30.10.30.40.30.50.10.70.1
Fecal boli incidents, locomotor time 10.10.20.6-0.5-0.50.00.0-0.1-0.2-0.6-0.5-0.3-0.8-0.20.40.20.10.60.0
Change in fecal boli incidents, locomotor task0.10.10.40.5-0.1-0.2-0.3-0.40.30.20.30.40.30.30.40.10.70.10.5
Time >=10cm from walls, locomotor time 10.40.41.0-0.0-0.2-0.2-0.5-0.4-0.3-0.9-0.9-0.7-0.9-1.00.0-0.5-0.4-0.9-0.8
Bouts of movement, locomotor time 10.40.50.9-1.0-0.7-0.8-0.6-0.7-0.8-0.6-0.5-0.7-0.5-0.8-1.0-0.9-0.8-0.4-0.4
Total resting periods, locomotor time 10.60.61.5-0.7-0.3-0.6-0.5-0.6-0.8-0.5-0.5-0.8-0.2-0.9-1.2-1.0-1.2-0.9-0.9
Rest time, locomotor task time 10.50.61.5-0.8-1.0-0.6-0.9-0.6-0.8-1.2-1.2-0.8-1.2-1.00.1-0.4-0.20.1-0.4
Distance moved, locomotor task time 10.00.00.10.1-0.0-0.10.30.10.1-0.0-0.1-0.1-0.1-0.00.10.1-0.1-0.1-0.2
Vertical activity count, locomotor time 10.10.10.50.50.5-0.00.10.00.00.30.30.10.5-0.1-0.3-0.3-0.4-0.7-0.5
Time >=10cm from walls, locomotor time 20.60.92.9-0.6-0.4-0.8-1.1-0.8-1.0-0.6-0.3-0.70.1-0.9-1.2-1.3-1.2-1.7-1.1
Bouts of movement, locomotor time 20.40.61.80.71.31.10.81.10.50.61.20.1-0.00.1-0.20.3-0.70.0-1.0
Total resting periods, locomotor time 20.40.61.80.81.31.20.91.10.60.71.30.20.10.2-0.10.3-0.60.1-0.9
Rest time, locomotor task time 23.44.39.31.90.92.01.81.92.31.71.62.41.21.93.02.52.72.71.9
Distance moved, locomotor task time 22.63.14.5-1.9-1.5-1.9-1.7-1.7-2.0-1.8-1.7-2.1-1.6-1.6-2.1-1.8-1.7-1.6-1.0
Vertical activity count, locomotor time 22.73.75.8-1.8-1.4-2.1-2.1-2.0-2.3-1.9-1.6-2.1-1.4-1.7-2.4-2.3-2.1-1.8-1.4
Light reinforcement 10.30.82.9-0.5-1.4-0.6-1.0-0.9-0.6-1.7-1.2-0.5-0.9-0.30.80.30.60.40.6
Light reinforcement 22.33.66.6-2.6-2.5-2.1-2.4-2.4-2.3-2.3-1.9-1.8-1.7-1.6-1.1-1.4-1.0-0.8-0.7
Bone: marrow area1.83.96.2-2.2-2.3-2.3-2.1-2.0-2.1-2.5-2.4-2.2-2.1-2.1-1.4-1.9-1.1-0.7-1.0
Bone: maximum diameter5.610.416.2-3.8-3.7-4.0-3.8-4.0-3.7-3.5-3.2-3.2-2.9-3.2-2.7-3.4-2.3-1.6-1.5
Bone: maximum force2.34.06.4-1.6-0.9-1.6-1.7-1.7-2.0-1.8-1.4-2.2-1.7-2.3-2.5-2.4-2.5-2.4-2.5
Bone: maximum moment2.95.07.7-1.7-1.1-1.8-1.9-1.9-2.3-2.0-1.6-2.5-1.9-2.7-2.7-2.7-2.8-2.7-2.8
Mean time between licks in bursts0.51.32.11.40.91.00.91.21.10.90.91.21.41.21.31.21.31.01.3
Mean num. licks in bursts1.11.72.7-1.2-1.1-1.3-1.4-1.3-1.4-1.2-1.2-1.5-1.3-1.4-1.6-1.4-1.3-0.8-1.1
Cd content in liver0.10.20.30.0-0.1-0.4-0.6-0.4-0.3-0.4-0.5-0.5-0.6-0.5-0.4-0.5-0.3-0.1-0.2
Co content in liver0.20.22.20.2-0.2-0.3-0.3-0.2-0.10.2-0.00.3-0.00.10.40.10.51.50.6
Cu content in liver5.66.712.43.03.33.43.23.52.82.73.02.33.02.21.52.30.81.0-0.1
Fe content in liver0.70.81.9-0.8-0.3-0.7-0.8-0.7-0.9-0.5-0.2-0.8-0.5-1.2-1.4-1.3-1.3-0.2-1.3
K content in liver0.00.00.2-0.10.00.20.50.10.1-0.00.0-0.00.30.2-0.10.1-0.20.2-0.3
Mg content in liver0.10.10.5-0.00.50.50.70.50.30.20.1-0.00.50.1-0.30.0-0.50.1-0.7
Mn content in liver0.50.51.8-1.1-1.3-0.9-0.7-0.9-0.6-0.8-0.7-0.3-0.50.20.40.20.50.60.8
Na content in liver1.51.63.71.81.71.61.91.51.61.41.01.01.11.00.71.00.3-0.0-0.1
Rb content in liver0.60.72.50.30.90.30.30.4-0.20.10.2-0.50.6-0.7-1.4-0.9-1.6-0.9-1.5
Se content in liver0.20.30.6-0.2-0.00.20.80.40.50.30.60.50.70.70.40.50.5-0.00.8
Sr content in liver1.21.12.61.10.60.90.71.01.00.80.61.10.51.01.61.31.50.11.4
Zn content in liver0.30.30.90.20.10.40.70.50.6-0.1-0.00.1-0.40.30.60.60.70.90.9
Bone: minimum diameter1.12.14.4-2.0-2.1-2.0-1.7-2.0-1.6-1.7-1.5-1.2-1.2-1.1-0.9-1.1-0.40.10.1
Time in familiar zone, hab. session 10.80.71.7-1.1-1.2-1.0-0.8-0.9-0.9-1.3-1.0-0.9-0.7-0.8-0.6-0.8-0.5-0.2-0.1
Time in novel zone, hab. session 10.10.10.60.50.4-0.2-0.1-0.10.00.40.20.10.3-0.2-0.4-0.4-0.2-0.8-0.3
Total zone transitions, hab. session 11.62.24.41.81.81.52.11.71.81.61.91.31.61.60.81.20.70.40.4
Total locomotion distance, hab. session 10.20.30.60.50.10.40.50.40.60.20.10.2-0.10.80.70.80.80.60.5
Locomotion velocity, hab. session 10.20.40.90.50.00.30.40.40.60.20.00.3-0.20.81.00.91.00.90.6
Time in familiar zone, hab. session 20.30.31.5-0.4-0.6-0.10.2-0.10.1-0.1-0.10.40.50.40.40.50.71.01.2
Time in novel zone, hab. session 20.30.31.10.81.00.30.10.30.30.70.60.20.20.1-0.4-0.3-0.4-1.0-0.8
Total zone transitions, hab. session 20.40.51.5-0.5-0.2-0.5-0.3-0.4-0.6-0.5-0.3-0.9-0.2-0.6-1.1-0.9-1.1-1.1-1.2
Total locomotion distance, hab. session 20.10.10.2-0.3-0.3-0.3-0.2-0.3-0.4-0.3-0.3-0.5-0.4-0.2-0.4-0.3-0.4-0.3-0.5
Locomotion velocity, hab. session 20.10.10.2-0.2-0.3-0.2-0.2-0.3-0.3-0.2-0.2-0.4-0.4-0.2-0.2-0.3-0.3-0.1-0.4
Novel to familiar place preference ratio0.20.21.11.00.60.40.10.40.50.20.50.40.00.00.40.20.6-0.00.7
Novelty place preference0.10.20.80.80.30.1-0.20.10.3-0.10.30.2-0.3-0.10.40.10.70.10.9
Time in novel zone, NPP test0.20.21.00.90.40.2-0.20.20.4-0.10.20.2-0.2-0.20.40.10.8-0.11.0
Total zone transitions, NPP test0.81.12.31.01.41.51.11.51.01.31.30.91.11.20.41.00.30.3-0.0
Total locomotion distance, NPP test0.20.30.70.30.50.80.50.80.40.70.60.30.10.60.40.70.30.20.1
Locomotion velocity, NPP test0.30.51.00.30.51.00.71.00.60.70.70.50.20.80.71.00.50.70.2
Intraocular pressure0.40.63.3-0.7-1.1-0.60.2-0.20.1-0.4-0.20.3-0.10.71.10.71.01.81.1
Delta distance traveled before/after self-admin0.70.71.4-0.7-0.8-0.9-1.2-0.9-1.1-1.0-0.9-0.8-0.6-0.8-0.6-0.9-0.6-0.5-0.6
Delta ambulatory time before/after self-admin0.40.51.0-0.7-0.7-0.7-0.9-0.6-1.0-0.9-0.7-0.7-0.4-0.7-0.5-0.7-0.6-0.4-0.5
Parametrial fat weight1.02.46.41.20.61.61.21.51.50.91.01.70.81.72.52.12.02.11.1
Pavlov. Cond. lever latency0.70.92.61.31.61.51.01.50.80.5-0.4-0.2-0.3-0.20.10.4-0.5-1.3-1.2
Pavlov. Cond. magazine entry latency0.30.42.4-0.1-0.1-0.5-0.3-0.5-0.30.71.00.81.50.3-0.4-0.6-0.2-0.1-0.1
Pavlov. Cond. change in total contacts0.50.51.5-0.5-0.6-1.1-0.4-1.2-0.70.00.60.31.0-0.3-0.7-1.1-0.6-0.4-0.3
Pavlov. Cond. index score0.30.41.1-0.7-0.7-1.0-0.6-1.0-0.60.20.80.51.10.1-0.5-0.6-0.10.30.2
Pavlov. Cond. latency score0.40.41.3-0.8-0.9-1.1-0.7-1.2-0.7-0.00.60.30.80.0-0.5-0.7-0.10.30.3
Pavlov. Cond. lever contacts0.80.92.5-1.3-1.6-1.4-0.9-1.5-0.8-0.40.40.40.60.30.1-0.30.51.41.2
Pavlov. Cond. magazine entry number0.30.32.30.20.10.40.20.30.2-0.8-1.1-0.8-1.5-0.40.30.30.1-0.10.1
Pavlov. Cond. intertrial magazine entries0.91.11.70.91.11.31.21.11.11.21.21.11.31.20.71.10.50.80.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.3-0.5-0.5-0.8-0.3-0.8-0.40.40.90.71.20.3-0.3-0.40.00.50.3
Pavlov. Cond. response bias0.50.61.7-0.9-1.0-1.1-0.7-1.0-0.70.20.80.71.30.3-0.2-0.50.10.80.5
Pavlov. Cond. lever latency0.60.81.30.70.60.81.00.70.90.80.90.90.91.11.01.01.00.90.8
Pavlov. Cond. magazine entry latency0.91.13.60.61.60.90.81.10.40.70.9-0.00.5-0.3-1.1-0.5-1.5-1.7-1.9
Pavlov. Cond. change in total contacts0.91.55.2-0.30.1-0.8-0.6-0.8-0.8-0.2-0.6-0.9-0.9-1.6-1.7-1.7-1.8-2.3-1.8
Pavlov. Cond. index score0.40.52.1-0.10.4-0.1-0.20.0-0.3-0.0-0.1-0.5-0.3-0.8-1.1-0.8-1.2-1.4-1.3
Pavlov. Cond. latency score0.50.72.4-0.20.3-0.2-0.2-0.1-0.4-0.2-0.2-0.6-0.4-0.9-1.2-0.9-1.4-1.5-1.5
Pavlov. Cond. lever contacts0.50.71.4-0.7-0.4-0.7-0.9-0.7-0.8-0.6-0.6-0.8-0.6-1.1-1.2-1.0-1.1-1.1-0.9
Pavlov. Cond. magazine entry number0.40.52.0-0.4-0.9-0.3-0.3-0.4-0.1-0.4-0.10.30.30.50.80.51.11.41.3
Pavlov. Cond. intertrial magazine entries0.81.22.3-1.2-0.7-0.9-0.8-1.0-1.2-0.8-0.8-1.2-0.8-1.2-1.5-1.3-1.5-1.4-1.1
Pavlov. Cond. lever-magazine prob. diff.0.30.41.50.10.50.1-0.00.2-0.10.1-0.1-0.3-0.3-0.6-0.9-0.6-1.0-1.2-1.2
Pavlov. Cond. response bias0.30.31.3-0.10.2-0.2-0.3-0.1-0.30.0-0.1-0.3-0.3-0.8-0.9-0.7-1.0-1.1-0.9
Time in closed arm before self-admin1.11.44.30.81.10.81.31.11.21.61.91.42.11.40.10.60.50.71.0
Time in closed arm after self-admin0.50.51.20.50.40.30.60.40.70.91.11.01.00.80.50.40.70.71.1
Time in open arm before self-admin0.30.31.20.40.10.70.40.40.4-0.4-0.5-0.0-0.70.11.10.70.50.5-0.3
Time in open arm after self-admin0.20.20.80.1-0.00.60.20.40.2-0.5-0.5-0.2-0.90.20.70.80.40.5-0.3
Bone: periosteal estimation2.55.47.7-2.6-2.6-2.8-2.7-2.7-2.6-2.6-2.5-2.4-2.2-2.4-1.9-2.3-1.6-1.2-1.3
Bone: periosteal perimeter3.45.811.1-3.0-3.3-3.3-3.1-3.3-2.8-2.7-2.4-2.0-1.9-2.1-1.3-2.2-0.9-0.2-0.3
Bone: post-yield work0.30.51.81.11.10.70.50.60.30.00.50.00.3-0.4-0.1-0.2-0.7-1.0-1.3
Progressive ratio test 1 active lever presses0.40.62.8-0.9-1.0-0.20.20.20.1-0.0-0.20.20.40.80.70.81.01.71.1
Progressive ratio test 1 breakpoint0.50.62.9-0.8-0.9-0.10.30.30.20.1-0.10.40.50.90.80.91.11.71.1
Progressive ratio test 1 inactive lever presses0.30.41.6-1.3-1.1-0.6-0.5-0.2-0.6-0.7-0.9-0.6-0.70.10.10.20.20.60.4
Progressive ratio test 2 active lever presses0.40.51.7-1.3-0.5-0.8-0.3-0.1-0.9-0.1-0.6-0.9-0.6-0.2-1.2-0.6-1.0-0.2-0.8
Progressive ratio test 2 breakpoint0.40.41.5-1.2-0.5-0.7-0.2-0.0-0.8-0.1-0.5-0.8-0.6-0.1-1.0-0.5-0.8-0.1-0.7
Progressive ratio test 2 inactive lever presses0.30.52.5-1.6-0.6-0.8-0.4-0.1-0.9-0.1-0.4-0.7-0.20.1-1.3-0.6-0.80.0-0.2
Incentive Sensitization - Responses0.71.13.2-1.2-0.2-0.9-0.6-0.3-1.1-0.1-0.5-1.1-0.6-0.6-1.8-1.2-1.7-1.0-1.5
Incentive Sensitization - Breakpoint1.01.23.3-1.3-0.3-1.0-0.7-0.4-1.3-0.3-0.6-1.2-0.8-0.7-1.8-1.3-1.7-1.0-1.6
Sum of active levers in priming session hrs 5-60.30.31.5-0.20.2-0.4-0.1-0.2-0.20.1-0.1-0.3-0.5-0.5-0.9-0.9-0.8-1.2-0.6
Progressive ratio0.10.20.50.60.50.30.70.50.50.70.70.60.00.40.40.30.30.30.1
Food seeking constrained by brief footshock0.80.91.4-1.0-0.8-1.0-0.7-1.0-1.0-1.2-0.9-1.0-0.9-1.1-1.0-1.0-1.1-1.1-0.6
Seeking ratio, punishment vs. effort1.52.24.2-1.4-0.7-1.0-1.3-1.2-1.5-1.4-1.3-1.7-0.7-1.6-2.0-1.6-2.0-2.0-1.5
Retroperitoneal fat weight2.18.915.1-3.9-3.4-3.1-3.5-3.0-3.5-3.2-3.0-3.1-3.3-3.0-2.2-2.6-2.4-1.7-2.3
Reaction time number correct0.30.51.30.80.50.50.80.60.80.70.70.80.40.81.10.80.90.70.3
Reaction time mean minus median0.30.61.20.60.50.50.80.71.01.00.61.00.30.81.00.70.91.10.8
Reaction time mean minus median AUC0.30.82.70.50.20.60.90.91.00.3-0.20.6-0.60.71.61.11.11.60.6
Reaction time num false alarms0.50.72.9-0.1-0.6-0.30.3-0.10.40.30.30.70.30.90.80.51.31.71.7
Reaction time num false alarms AUC0.50.83.9-0.3-0.7-0.20.2-0.20.40.30.20.70.21.00.90.71.41.92.0
Reaction time trials correct on left0.30.51.30.80.50.50.80.60.80.70.70.80.40.81.10.80.90.70.3
Reaction time trials on left0.30.61.40.90.50.50.80.60.80.70.80.90.50.91.20.90.90.70.3
Reaction time mean1.01.64.11.62.01.51.71.81.41.71.31.01.20.90.00.6-0.2-0.6-0.6
Reaction time mean AUC1.21.94.51.82.11.72.02.01.71.71.41.11.21.10.20.80.0-0.4-0.4
Median of all reaction times1.31.84.91.62.21.61.81.91.41.61.40.81.30.8-0.40.4-0.6-1.2-1.0
Reaction time omissions0.71.02.41.61.31.21.01.21.11.11.11.01.00.90.80.90.60.20.0
Reaction time false alarm rate0.30.42.2-0.8-0.9-0.6-0.3-0.6-0.1-0.1-0.30.1-0.10.30.00.00.71.21.5
Reaction time premature initiation rate1.92.66.0-0.9-0.0-1.1-1.1-1.1-1.5-0.7-0.7-1.5-1.2-2.0-2.4-2.2-2.5-2.4-2.2
Reaction time premature initiations0.61.13.2-0.20.4-0.7-0.5-0.6-0.8-0.2-0.1-0.8-0.8-1.3-1.4-1.4-1.7-1.8-1.8
Std. dev. reaction times0.61.11.91.11.21.01.21.31.31.41.01.20.81.10.80.90.70.70.5
Reaction time trials completed0.30.61.40.90.50.50.80.60.80.70.80.90.50.91.20.90.90.70.3
Reaction time trials AUC0.10.30.90.60.30.20.60.40.60.50.50.60.30.60.90.60.70.50.1
Run reversals in cocaine runway, females0.70.72.50.90.20.40.30.00.70.80.61.01.60.81.00.71.20.51.2
Run reversals in cocaine runway, males0.60.61.9-0.6-1.2-1.0-0.6-0.5-0.3-0.4-0.7-0.1-0.80.00.80.01.11.41.2
Latency to leave start box in cocaine runway1.31.52.4-1.5-1.4-1.4-1.2-1.5-1.3-1.5-1.3-1.4-1.0-1.0-1.0-1.3-0.8-0.4-0.7
Latency to leave start box in cocaine runway, F1.31.42.6-1.4-1.4-1.3-1.2-1.3-1.3-1.6-1.4-1.4-0.9-1.2-1.0-1.3-0.8-0.6-0.6
Latency to leave start box in cocaine runway, M0.30.30.6-0.8-0.6-0.8-0.5-0.8-0.5-0.5-0.2-0.5-0.5-0.2-0.5-0.6-0.3-0.0-0.4
Std. dev. time between licks in bursts0.30.42.20.30.40.2-0.3-0.0-0.40.10.1-0.10.5-0.5-0.5-0.4-0.7-1.5-1.2
Total sessions with >9 infusions1.61.93.9-1.7-2.0-1.8-1.4-1.4-1.4-1.5-1.7-1.4-2.0-1.1-0.6-1.0-0.20.30.3
Short access day 1 total inactive lever presses2.73.56.1-2.5-2.2-2.2-2.2-2.0-2.4-2.0-1.6-1.9-1.1-1.7-1.9-2.0-1.5-1.1-0.9
Short access day 10 total inactive lever presses0.40.92.0-1.4-0.9-0.9-1.2-1.2-1.1-0.8-0.7-0.9-1.3-0.9-0.6-0.8-0.8-0.4-0.8
Short access day 1 total infusions0.81.03.2-1.2-1.5-1.8-1.1-1.3-1.0-0.8-1.0-0.8-0.9-0.7-0.5-0.90.10.10.8
Short access day 10 total infusions1.11.44.6-2.1-2.1-1.9-1.4-1.3-1.4-1.0-1.0-0.9-0.8-0.5-0.6-0.8-0.10.50.4
Short access total infusions1.82.35.6-2.4-2.1-2.2-1.6-1.6-1.7-1.3-1.5-1.5-1.4-1.1-1.4-1.4-0.7-0.10.2
Short access day 1 locomotion0.10.10.5-0.4-0.5-0.7-0.1-0.3-0.3-0.2-0.3-0.3-0.6-0.2-0.4-0.5-0.1-0.40.2
Short access day 10 total locomotion0.61.24.4-0.0-1.00.10.10.10.6-0.0-0.30.70.01.02.11.42.11.71.5
Short access total locomotion0.30.31.3-0.9-1.1-0.8-0.5-0.5-0.3-0.5-0.6-0.2-0.50.10.30.10.60.60.7
One hour access (0.3 mA shock)0.91.03.7-1.9-1.3-1.4-0.9-0.7-1.3-0.9-1.1-1.1-0.9-0.5-1.2-0.7-0.60.10.0
Compulsive drug intake0.30.31.30.20.40.0-0.4-0.2-0.4-0.3-0.4-0.6-0.6-0.8-0.6-0.6-0.8-1.1-0.9
One hour access (shock baseline)0.61.04.2-2.1-1.7-1.6-0.8-0.8-1.1-0.6-0.7-0.7-0.20.0-1.0-0.5-0.10.70.8
Social response proportion1.61.83.3-1.4-1.4-1.7-1.8-1.8-1.6-1.2-1.1-1.2-1.0-1.4-1.2-1.4-0.8-1.2-0.5
Social responses1.01.33.4-1.1-1.8-1.6-1.7-1.6-1.2-1.4-1.3-0.7-1.1-0.70.2-0.70.30.20.4
Social time0.70.92.30.4-0.20.20.10.20.60.61.01.21.21.11.21.01.41.51.4
Soleus weight0.51.32.0-1.3-0.9-1.0-1.0-1.1-1.3-0.9-0.5-1.2-0.7-1.4-1.4-1.3-1.4-1.3-1.4
Bone: stiffness1.32.17.8-0.00.8-0.2-0.0-0.2-0.7-0.5-0.3-1.3-0.5-1.6-2.1-1.7-2.4-2.8-2.5
Tibialis anterior weight0.10.30.90.80.90.90.91.00.60.00.30.00.1-0.10.00.3-0.1-0.5-0.4
Time to tail flick, vehicle, before self-admin0.30.30.80.50.20.40.70.40.6-0.1-0.30.30.30.50.90.60.60.90.2
Time to tail flick, vehicle, after self-admin0.10.10.4-0.3-0.4-0.60.1-0.20.10.10.20.20.40.2-0.1-0.10.20.30.6
Time to tail flick, test, before self-admin0.90.92.5-1.1-1.5-1.1-1.6-1.4-1.1-1.1-1.0-0.7-0.9-0.7-0.1-0.60.30.10.6
Time to tail flick, test, after self-admin0.80.82.9-0.7-0.1-1.0-0.8-0.8-0.70.10.2-0.40.7-0.5-1.7-1.2-1.1-1.6-0.6
Delta time to tail flick, vehicle, before/after SA1.21.21.8-0.9-0.8-1.2-1.2-1.1-1.2-0.9-1.0-1.1-1.2-1.3-1.0-1.3-1.1-0.9-1.0
Delta time to tail flick, test, before/after SA0.91.02.30.81.50.51.00.80.81.41.40.71.50.6-0.9-0.2-0.7-1.0-0.7
Tibia length0.10.41.1-1.0-0.9-0.8-0.7-0.7-0.8-0.30.1-0.2-0.0-0.4-0.7-0.7-0.50.2-0.2
Ambulatory time before self-admin0.40.62.7-0.0-0.40.20.20.30.60.40.40.70.20.80.80.91.31.21.6
Ambulatory time after self-admin0.10.10.7-0.3-0.2-0.2-0.4-0.2-0.30.30.50.30.80.2-0.5-0.30.0-0.00.6
Bone: tissue strength0.30.31.50.30.70.50.30.3-0.00.30.6-0.10.2-0.4-0.6-0.3-0.9-1.0-1.2
Total heroin consumption1.61.95.7-1.4-0.5-0.7-0.4-0.5-1.2-1.1-1.0-1.6-1.2-1.1-1.7-1.4-2.2-1.5-2.4
Bone: trabecular number0.81.42.41.10.90.91.01.01.21.21.51.51.51.20.90.91.11.01.5
Bone: trabecular spacing2.93.87.3-1.8-2.0-1.9-1.8-2.0-1.9-2.5-2.7-2.2-2.7-2.2-0.9-1.7-1.3-0.9-1.8
Bone: trabecular thickness0.20.20.60.10.40.10.20.30.30.80.60.50.60.60.00.30.30.40.7
Bone: trabecular tissue density0.81.12.91.41.71.41.71.51.31.41.00.80.50.70.20.60.1-0.1-0.1
Water consumed over 24 hours1.21.63.1-1.1-1.4-1.8-1.7-1.7-1.3-1.3-1.2-1.1-1.4-1.5-1.0-1.5-0.60.1-0.1
Number of responses in last shaping day0.10.10.80.90.40.20.40.20.30.1-0.10.30.30.10.4-0.00.2-0.1-0.0