Cela1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	Cela1	0.06	0.04	2.7e-06	0.03	0.05	0.05	0.05	8.5e-05	3.0e-06	1.4e-06	4.5e-06
2	BLA	gene expression	Cela1	0.1	0.07	2.5e-04	0.05	0.06	0.07	0.03	8.0e-04	6.0e-04	1.3e-04	6.1e-03
3	PL	gene expression	Cela1	0.11	0.06	2.5e-11	0.07	0.09	0.09	0.11	1.1e-08	3.6e-10	1.9e-10	1.1e-11
4	pVTA	intron excision ratio	chr7_131773464_131774060	0.14	0.11	1.1e-03	0.03	0.05	0.05	0.05	2.7e-02	2.7e-03	4.5e-03	4.1e-03
5	LHb	gene expression	Cela1	0.24	0.13	1.8e-03	0.01	0.05	0.06	0.03	1.5e-01	2.6e-02	1.7e-02	7.3e-02
6	Brain	gene expression	Cela1	0.07	0.04	4.3e-05	0.06	0.05	0.04	0.06	2.0e-06	2.7e-05	1.8e-04	6.5e-06
7	pVTA	gene expression	Cela1	0.45	0.23	2.3e-05	0.1	0.1	0.12	0.11	4.1e-05	3.1e-05	1.0e-05	2.3e-05
8	Liver	gene expression	Cela1	0.84	0.03	0.0e+00	0.49	0.51	0.5	0.51	3.0e-62	1.1e-64	2.3e-63	5.1e-65
9	Adipose	gene expression	Cela1	0.48	0.15	2.6e-12	0.08	0.1	0.1	0.09	1.3e-09	1.7e-11	3.6e-11	3.2e-10
10	Liver	mRNA stability	Cela1	0.48	0.1	0.0e+00	0.31	0.34	0.34	0.34	5.8e-35	1.4e-38	2.3e-39	6.4e-39

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	7.1	11.8	16.0	-4.0	-4.0	3.3	3.7	-3.9	-3.1	-3.8	3.0	3.3	-2.0
Area under the delay curve	0.4	0.5	1.0	-0.8	-0.9	1.0	0.9	-0.9	-0.3	-0.3	0.4	0.1	-0.0
BMI with tail	2.5	8.2	17.3	-3.9	-4.0	4.2	3.6	-2.3	-2.7	-2.1	1.6	1.4	-0.3
BMI without tail	1.4	3.0	5.6	-1.8	-1.7	1.5	1.6	-1.0	-1.9	-2.2	1.6	2.4	-1.0
Body weight	3.4	14.4	25.4	-4.8	-4.6	5.0	4.6	-3.6	-4.0	-3.2	2.7	2.2	-1.5
Weight adjusted by age	0.4	0.5	1.3	-0.3	-0.4	0.4	-0.2	0.4	0.5	0.8	-0.9	-1.0	1.1
Bone surface	8.8	15.6	20.4	-4.5	-4.4	4.0	4.4	-4.5	-3.6	-4.2	3.5	3.3	-2.5
Bone volume	8.4	14.2	19.3	-4.4	-4.4	3.8	4.1	-4.2	-3.3	-4.2	3.2	3.5	-2.1
Breakpoint value in progressive ratio session	0.3	0.3	0.7	-0.2	0.1	0.3	0.6	-0.5	-0.5	-0.6	0.7	0.7	-0.9
Number of licking bursts	2.0	2.4	3.9	1.6	2.0	-0.9	-1.5	1.5	1.6	2.0	-1.5	-1.5	1.2
Context. condit. distance diff. score	1.0	1.2	2.1	-0.9	-1.4	0.9	1.0	-1.1	-1.4	-0.7	1.2	0.9	-1.0
Locomotion velocity, session 1	4.1	4.4	6.3	2.4	2.5	-2.3	-2.2	2.0	2.5	2.0	-1.5	-2.2	0.8
Locomotion distance, session 1	3.2	4.1	6.4	2.3	2.3	-2.2	-2.2	2.0	2.5	1.3	-1.8	-2.0	1.3
Locomotion velocity, session 2	0.5	0.6	1.1	1.0	1.1	-0.7	-0.6	0.4	0.8	0.9	-0.4	-0.9	-0.0
Locomotion distance, session 2	3.6	5.0	8.1	2.6	2.9	-2.5	-2.5	2.3	2.6	1.5	-1.9	-1.9	1.2
Locomotion velocity, session 3	2.6	3.1	7.4	2.5	2.7	-2.4	-2.0	1.6	1.4	1.2	-0.7	-1.1	-0.2
Locomotion distance, session 3	1.0	1.1	3.4	1.2	1.3	-1.8	-0.9	-0.0	-0.1	-0.6	0.8	1.1	-1.4
Stereotopy head waving bouts, day 3	1.9	2.2	3.9	0.9	1.3	-0.3	-1.0	1.7	2.0	1.4	-1.9	-1.6	1.9
Stereotopy head waving duration, day 3	0.8	1.0	1.8	1.0	1.3	-0.5	-0.8	1.3	1.3	0.8	-1.0	-0.9	0.8
Locomotion velocity, session 7	1.2	1.3	3.7	1.6	1.8	-1.9	-1.2	0.8	0.4	-0.4	0.3	0.9	-0.9
Locomotion distance, session 7	1.4	1.8	4.9	2.0	2.0	-2.2	-1.6	1.2	0.7	0.3	0.1	-0.2	-0.9
Stereotopy head waving bouts, day 7	0.5	0.6	2.2	-0.2	0.0	0.6	0.1	0.1	1.1	0.6	-1.1	-0.4	1.5
Stereotopy head waving duration, day 7	0.5	0.6	1.9	-0.3	0.0	1.0	0.4	0.2	0.8	0.7	-1.0	-0.6	1.4
Locomotion velocity, session 8	0.4	0.5	0.8	0.9	0.8	-0.7	-0.8	0.9	0.8	0.6	-0.6	-0.6	0.3
Locomotion distance, session 8	0.5	0.7	1.4	1.1	0.9	-1.2	-1.0	0.6	0.6	0.7	-0.3	-0.9	-0.1
Degree of sensitization distance	0.5	0.5	1.5	0.3	0.1	0.1	-0.3	1.0	0.8	0.8	-0.8	-1.2	0.8
Degree of sensitization stereotypy	0.4	0.4	1.6	-0.5	-0.4	0.9	0.3	-0.3	0.7	0.6	-0.8	-0.3	1.3
Conditioned locomotion	0.1	0.1	0.3	0.3	0.5	-0.4	-0.0	0.5	-0.2	-0.0	0.2	0.3	-0.3
Cocaine response after cond. corrected	0.5	0.6	1.4	0.7	1.0	-0.2	-0.5	0.9	1.2	0.3	-0.8	-0.8	0.8
Cocaine response after cond. not corrected	0.4	0.4	1.0	0.7	1.0	-0.6	-0.6	0.8	0.8	-0.2	-0.5	-0.4	0.3
Cocaine response before conditioning	0.4	0.4	1.6	0.8	0.6	-1.2	-0.7	0.2	-0.3	-0.3	0.5	0.2	-0.9
Saline control response	0.7	0.9	2.4	-0.5	-0.3	-0.0	0.6	-0.6	-0.8	-1.6	1.2	1.5	-1.2
Bone: connectivity density	3.7	5.9	9.1	-2.6	-2.7	2.2	2.6	-3.0	-2.2	-2.6	2.3	2.0	-1.8
Bone: cortical apparent density	1.3	1.8	3.7	0.9	0.7	-1.1	-1.3	1.9	1.4	0.7	-1.7	-1.0	1.8
Bone: cortical area	5.5	8.2	11.0	-3.3	-3.1	3.0	3.3	-2.9	-2.7	-3.3	2.5	2.5	-1.7
Bone: cortical porosity	1.5	1.6	2.6	-0.8	-0.7	0.3	0.9	-1.4	-1.6	-1.4	1.6	1.6	-1.5
Bone: cortical porosity	1.1	1.2	2.3	-0.4	-0.4	-0.0	0.6	-1.0	-1.4	-1.4	1.4	1.5	-1.4
Bone: cortical thickness	1.7	2.7	4.4	-2.0	-1.9	1.7	1.8	-1.4	-1.6	-2.1	1.4	1.3	-0.9
Bone: cortical thickness	0.3	0.3	1.4	0.1	0.4	-0.3	0.0	0.2	-0.6	-1.2	0.5	0.5	-0.7
Bone: cortical tissue density	1.5	2.0	4.0	1.1	0.9	-1.3	-1.4	2.0	1.4	0.8	-1.7	-1.0	1.8
Condit. Reinf. active minus inactive responses	0.1	0.1	0.3	0.3	0.3	-0.2	-0.1	0.3	0.1	-0.2	-0.1	-0.5	0.1
Condit. Reinf. active-inactive response ratio	0.5	0.6	1.3	-0.3	-0.3	0.3	0.7	-0.4	-1.0	-1.1	1.0	0.5	-1.0
Condit. Reinf. active responses	0.7	0.9	2.0	1.0	0.8	-0.8	-1.0	1.0	0.9	0.7	-0.9	-1.4	0.8
Condit. Reinf. inactive responses	3.8	4.5	5.9	1.9	1.7	-1.8	-2.3	2.2	2.4	2.2	-2.3	-2.3	1.9
Incentive salience index mean	0.1	0.1	0.6	-0.1	-0.2	0.2	0.1	0.1	-0.0	0.0	-0.3	-0.8	0.4
Condit. Reinf. lever presses	0.4	0.5	1.4	-0.4	-0.6	0.8	0.3	0.2	0.2	0.6	-0.7	-1.2	1.0
Condit. Reinf. active minus inactive responses	0.6	0.7	1.9	-1.2	-1.4	1.2	1.0	-0.9	-0.2	-0.5	0.1	-0.2	0.3
Condit. Reinf. active-inactive response ratio	0.5	0.5	1.2	-1.0	-1.0	1.1	0.9	-0.7	-0.4	-0.7	0.3	-0.2	-0.0
Condit. Reinf. active responses	0.1	0.2	0.6	-0.7	-0.8	0.5	0.4	-0.4	0.2	-0.4	-0.0	0.2	0.3
Condit. Reinf. inactive responses	0.3	0.4	0.9	0.6	0.4	-1.0	-0.8	0.4	0.8	0.5	-0.5	0.2	0.5
Condit. Reinf. lever presses	0.3	0.4	0.8	-0.5	-0.5	0.1	0.3	-0.7	-0.6	-0.7	0.8	0.5	-0.9
Condit. Reinf. lever reinforcers received	0.0	0.0	0.2	-0.3	-0.4	0.1	0.1	-0.2	0.3	-0.2	-0.0	-0.0	0.1
Conditioned reinforcement - actives	1.5	1.5	3.1	1.6	1.8	-1.2	-1.2	1.2	1.4	0.8	-1.1	-0.6	0.8
Conditioned reinforcement - inactives	1.2	1.3	4.0	1.6	2.0	-1.3	-1.2	1.1	1.1	0.1	-0.9	-0.1	0.4
Conditioned locomotion	0.4	0.5	1.4	0.9	1.2	-0.4	-0.3	0.9	0.4	0.7	-0.2	-0.7	-0.2
Patch foraging indifference point 0 sec	1.8	2.9	9.6	2.4	2.0	-3.1	-2.2	1.6	1.3	0.5	-0.6	0.1	0.0
Patch foraging indifference point AUC	1.0	1.1	1.9	0.8	0.7	-0.6	-0.9	1.0	1.4	0.9	-1.3	-1.4	1.2
Delay disc. indifference point, 0s delay	1.2	1.3	3.7	-1.2	-1.4	1.4	1.3	-1.9	-0.8	-0.7	0.8	0.7	-0.4
Delay disc. indifference point, 16s delay	0.5	0.5	0.9	-0.8	-0.9	0.9	1.0	-0.9	-0.5	-0.5	0.5	0.5	-0.3
Delay disc. indifference point, 2s delay	0.8	0.9	2.3	-1.2	-1.5	1.3	0.7	-0.0	0.3	0.2	-0.7	-0.3	1.5
Delay disc. indifference point, 24s delay	0.2	0.2	0.4	-0.4	-0.6	0.6	0.6	0.1	-0.0	0.3	-0.0	-0.5	0.2
Delay disc. indifference point, 4s delay	0.4	0.4	1.0	-0.8	-1.0	1.0	0.9	-0.6	-0.4	-0.5	0.3	0.1	0.0
Delay disc. indifference point, 8s delay	1.3	1.4	2.0	-1.2	-1.2	1.2	1.4	-1.4	-1.1	-0.9	1.2	0.9	-0.9
Indifference point function ln k	3.5	4.9	7.4	-2.7	-2.5	2.5	2.7	-1.9	-2.2	-2.2	2.0	1.6	-1.4
Indifference point function log k	3.5	4.9	7.4	-2.7	-2.5	2.5	2.7	-1.9	-2.2	-2.2	2.0	1.6	-1.4
Patch foraging total patch changes 0 sec	1.6	2.5	8.8	2.2	1.9	-3.0	-2.0	1.5	1.1	0.2	-0.3	0.2	-0.3
Patch foraging total patch changes 12 sec	2.9	3.8	7.6	2.5	2.0	-2.8	-2.5	2.0	1.7	1.7	-1.4	-1.4	0.9
Patch foraging total patch changes 18 sec	3.3	4.2	9.7	2.7	2.4	-3.1	-2.7	1.7	2.0	1.4	-1.4	-1.1	0.7
Patch foraging total patch changes 24 sec	1.7	2.1	4.8	1.9	1.8	-2.2	-1.8	1.6	1.3	0.6	-0.9	-0.4	0.4
Patch foraging total patch changes 6 sec	3.4	5.1	11.2	3.0	2.5	-3.3	-2.8	2.3	2.2	1.3	-1.5	-1.2	0.8
Patch foraging time to switch 0 sec	1.0	1.5	3.2	1.5	1.2	-1.7	-1.8	1.1	0.8	1.2	-1.1	-0.2	1.0
Patch foraging water rate 0 sec	2.0	3.2	6.1	-2.1	-1.9	2.5	2.4	-1.7	-1.6	-1.5	1.6	0.8	-1.2
Patch foraging water rate 12 sec	2.1	3.2	4.3	-1.9	-1.7	1.9	2.1	-2.0	-1.8	-1.9	1.7	1.1	-1.5
Patch foraging water rate 18 sec	0.2	0.2	0.4	-0.4	-0.7	0.5	0.6	-0.5	-0.6	-0.4	0.3	0.0	-0.2
Patch foraging water rate 24 sec	2.0	2.8	4.7	-2.1	-2.1	2.2	2.2	-1.6	-1.6	-1.4	1.2	0.9	-0.7
Patch foraging water rate 6 sec	4.0	5.8	8.8	-2.9	-2.6	2.9	3.0	-2.8	-2.1	-2.2	2.1	1.3	-1.6
Seeking ratio, delayed vs. immediate footshock	0.4	0.5	1.4	-0.9	-1.2	0.9	0.8	-0.7	-0.6	-0.4	0.5	0.0	-0.1
Distance traveled before self-admin	1.3	1.4	2.7	1.6	1.4	-1.5	-1.5	1.2	0.9	1.1	-0.8	-0.6	0.5
Distance traveled after self-admin	0.3	0.3	0.7	0.7	0.8	-0.8	-0.6	0.0	-0.1	0.3	0.3	-0.1	-0.7
Extensor digitorum longus weight	1.8	7.2	18.1	-4.0	-4.1	4.3	3.2	-1.9	-0.8	-1.5	-0.1	1.1	2.0
Bone: elastic displacement	4.5	5.1	10.2	3.2	3.0	-3.2	-2.6	2.5	1.3	1.7	-1.0	-1.7	-0.1
Bone: elastic work	0.2	0.3	1.1	0.5	0.5	-0.5	-0.1	0.2	-0.5	-0.3	0.6	-0.6	-1.0
Bone: endosteal estimation	6.2	13.5	18.7	-4.0	-3.4	3.9	4.3	-4.0	-3.5	-3.7	3.5	3.5	-2.6
Bone: endosteal perimeter	5.5	11.4	15.8	-4.0	-3.5	3.9	4.0	-3.8	-2.7	-3.6	2.8	3.1	-1.8
Epididymis fat weight	1.1	2.7	6.9	-0.6	-0.6	0.7	1.2	-1.8	-2.4	-1.3	2.3	1.1	-2.6
Delta time in closed arm before/after self-admin	0.2	0.2	0.5	-0.4	-0.5	0.3	0.5	-0.7	-0.4	-0.2	0.5	0.6	-0.4
Delta time in open arm before/after self-admin	1.0	0.9	2.7	1.4	1.5	-1.6	-1.2	0.4	-0.1	-0.1	0.2	-0.0	-0.9
Diff in mean of infusions in LGA sessions	1.1	1.3	2.8	-1.7	-1.7	1.5	1.3	-1.1	-0.9	-0.6	0.6	0.7	-0.1
Delay discount exponential model param	0.4	0.4	1.0	0.8	1.0	-1.0	-0.8	0.7	0.3	0.2	-0.3	0.0	-0.1
Extinction: sum of active levers before priming	0.8	0.8	2.5	-1.4	-1.6	1.3	1.0	-0.7	-0.8	-0.2	0.4	0.1	0.0
Active lever presses in extinction session 6	0.1	0.1	0.3	-0.0	0.4	0.3	0.3	-0.4	-0.2	-0.5	0.3	0.1	-0.4
Bone: final force	10.0	16.2	20.9	-4.5	-4.3	4.2	4.6	-4.6	-4.0	-4.0	3.8	3.0	-2.8
Bone: final moment	11.6	18.9	24.0	-4.8	-4.6	4.4	4.9	-4.9	-4.4	-4.4	4.1	3.4	-3.2
Food consumed during 24 hour testing period	2.5	3.0	4.7	-1.6	-1.7	1.6	1.9	-2.1	-2.2	-1.2	1.9	0.7	-1.7
Glucose	0.0	0.0	0.1	-0.1	-0.1	-0.3	-0.2	0.1	0.3	-0.2	0.1	0.0	-0.0
Heart weight	0.6	0.9	1.7	-0.8	-0.8	0.3	0.7	-0.8	-1.3	-1.3	1.0	1.1	-0.8
Delay discount hyperbolic model param	0.4	0.4	1.1	0.9	1.0	-1.0	-0.8	0.6	0.2	0.2	-0.1	0.1	-0.3
Intermittent access intake day 1-15 change	0.5	0.5	1.2	0.2	-0.1	-0.3	0.0	-0.4	-0.7	-1.0	1.0	0.9	-1.1
Intermittent access intake escalation	0.9	0.9	1.9	0.0	-0.3	-0.1	0.4	-1.0	-1.1	-1.2	1.3	1.1	-1.4
Intermittent access intake escalation 2	0.9	0.8	1.6	-0.2	-0.4	-0.1	0.3	-1.0	-1.1	-1.3	1.2	1.2	-1.2
Intermitt. access day 1 inactive lever presses	0.2	0.2	0.5	0.6	0.7	-0.5	-0.3	0.5	0.3	-0.4	-0.1	0.3	-0.2
Intermitt. access day 15 inactive lever presses	0.1	0.1	0.4	0.5	0.4	-0.5	-0.2	0.6	-0.1	-0.3	0.2	0.2	-0.4
Intermitt. access escalation Index	2.4	2.1	4.4	1.1	0.9	-0.9	-1.4	1.3	1.4	2.1	-1.6	-1.6	1.6
Intermittent access day 1 total infusions	1.1	1.3	4.9	1.6	2.2	-1.3	-1.1	1.2	0.7	0.3	-0.5	-0.1	0.0
Intermittent access day 15 total infusions	0.9	1.0	3.1	1.6	1.8	-1.4	-1.0	0.6	0.2	-0.1	0.1	0.4	-0.6
Intermittent access terminal intake (last 3 days)	0.9	1.0	3.4	1.6	1.9	-1.4	-1.1	0.7	0.4	0.0	-0.1	0.4	-0.4
Intermittent access total infusions	1.0	1.1	4.1	1.7	2.0	-1.4	-1.0	0.7	0.4	-0.1	-0.1	0.3	-0.4
Intermittent access day 1 locomotion	1.1	1.2	4.2	1.7	2.0	-1.4	-1.0	1.0	0.4	0.6	-0.3	-0.1	-0.4
Intermittent access day 15 total locomotion	0.5	0.6	1.6	1.1	1.3	-1.0	-0.4	0.3	-0.2	-0.2	0.6	0.6	-1.1
Intermittent access total locomotion	2.1	2.4	7.2	2.4	2.7	-2.1	-1.6	1.5	1.0	0.7	-0.6	-0.2	-0.2
Intermittent access standard deviation	1.4	1.5	3.1	-0.3	-0.3	-0.0	0.5	-1.2	-1.5	-1.8	1.6	1.4	-1.8
Left kidney weight	1.5	4.1	5.8	-2.3	-2.3	1.9	2.2	-2.4	-2.2	-2.0	1.8	1.7	-1.3
Right kidney weight	1.9	5.3	9.6	-2.9	-3.1	2.7	2.5	-3.0	-2.2	-1.6	1.7	1.2	-0.8
Cocaine induced anxiety	1.8	2.1	3.4	-1.4	-1.3	1.1	1.4	-1.4	-1.9	-1.6	1.7	1.4	-1.4
Post-drug Anxiety	4.8	5.4	7.8	-2.8	-2.5	2.4	2.6	-1.9	-2.6	-2.3	2.2	1.9	-1.6
Baseline Anxiety	0.2	0.3	0.7	-0.8	-0.8	0.8	0.7	-0.3	-0.2	0.2	0.2	0.0	0.0
Tail length	0.7	2.2	6.9	-0.7	-0.3	0.4	0.9	-0.9	-1.4	-2.2	1.6	2.6	-1.6
Length with tail	1.6	6.0	7.9	-2.7	-2.5	2.7	2.8	-2.8	-2.5	-2.4	2.1	2.2	-1.6
Length without tail	2.3	4.9	9.6	-2.8	-2.8	3.1	2.7	-3.0	-1.8	-1.3	1.3	0.6	-0.6
Times rat made contact with spout	0.2	0.3	1.1	-0.3	-0.4	0.3	0.4	-1.0	-0.5	-0.2	0.7	0.2	-0.6
Lifetime Intake	1.4	1.6	6.0	2.0	2.5	-1.7	-1.2	0.9	0.5	0.0	-0.0	0.3	-0.6
Liver weight, left	2.1	3.3	4.4	-1.8	-1.3	1.8	2.0	-2.1	-2.0	-2.1	1.9	1.6	-1.6
Liver weight, right	2.3	3.8	5.9	-1.8	-1.7	1.7	2.1	-2.2	-2.1	-2.4	2.0	1.4	-1.8
Locomotor activity	0.6	1.0	2.6	0.9	1.1	-1.0	-1.1	0.8	1.6	0.8	-0.8	-0.9	0.5
Locomotor testing distance	1.2	2.1	3.9	1.7	1.7	-2.0	-1.8	1.2	1.8	1.0	-0.9	-1.0	0.5
Locomotor testing rearing	0.3	0.5	2.2	0.6	0.6	-1.5	-0.9	0.0	0.2	-0.3	0.3	0.7	-0.5
Locomotion in novel chamber	1.7	2.1	4.8	-2.2	-1.9	2.0	1.7	-0.6	-1.4	-1.4	0.8	1.1	-0.3
Locomotion in novel chamber post-restriction	0.7	0.8	1.3	-0.6	-0.6	0.7	1.0	-0.9	-1.1	-1.0	1.1	0.7	-1.1
Fecal boli incidents, locomotor time 1	0.5	0.6	1.8	1.2	1.4	-0.9	-0.5	-0.5	0.1	0.5	0.4	-0.2	-1.0
Change in fecal boli incidents, locomotor task	0.4	0.4	1.2	-0.0	-0.2	0.3	-0.1	1.1	0.6	0.0	-0.8	-0.6	1.1
Time >=10cm from walls, locomotor time 1	0.3	0.3	0.8	0.9	0.9	-0.6	-0.4	0.5	0.4	0.5	-0.2	-0.1	-0.1
Bouts of movement, locomotor time 1	0.4	0.4	1.4	0.5	0.4	-0.0	-0.3	0.1	0.6	0.9	-0.8	-1.2	0.7
Total resting periods, locomotor time 1	1.1	1.2	2.1	1.3	1.3	-0.7	-1.0	0.5	1.1	1.1	-1.2	-1.4	0.9
Rest time, locomotor task time 1	0.8	0.9	1.9	1.2	1.4	-1.0	-1.0	0.5	1.0	0.7	-0.9	-0.9	0.5
Distance moved, locomotor task time 1	0.1	0.1	0.7	-0.1	-0.0	-0.0	-0.2	0.8	0.3	0.4	-0.3	-0.2	0.3
Vertical activity count, locomotor time 1	0.8	0.9	2.3	-1.5	-1.5	1.1	1.0	-0.1	-1.0	-0.7	0.5	0.8	-0.1
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.6	0.8	0.6	-0.7	-0.5	-0.1	0.1	-0.0	0.0	0.0	-0.2
Bouts of movement, locomotor time 2	1.9	2.1	3.7	-1.9	-1.8	1.9	1.8	-1.2	-1.2	-1.3	1.0	1.0	-0.5
Total resting periods, locomotor time 2	2.0	2.1	4.1	-2.0	-1.9	2.0	1.9	-1.2	-1.0	-1.3	0.8	0.9	-0.2
Rest time, locomotor task time 2	0.3	0.4	1.0	0.6	0.7	-0.4	-0.5	1.0	0.7	0.3	-0.7	-0.6	0.6
Distance moved, locomotor task time 2	0.1	0.1	0.3	0.2	0.1	-0.4	-0.5	0.3	0.3	0.6	-0.4	-0.4	0.3
Vertical activity count, locomotor time 2	0.2	0.2	0.8	-0.6	-0.9	0.3	0.2	-0.7	-0.3	0.2	0.2	-0.0	-0.0
Light reinforcement 1	1.4	2.5	4.0	1.6	1.5	-1.3	-1.5	1.5	2.0	1.8	-1.6	-1.7	1.2
Light reinforcement 2	0.1	0.2	0.5	-0.1	-0.3	0.2	-0.1	-0.4	0.5	0.7	-0.5	-0.6	0.6
Bone: marrow area	6.0	13.0	17.8	-3.9	-3.4	3.8	4.2	-3.9	-3.5	-3.7	3.4	3.4	-2.6
Bone: maximum diameter	1.7	3.1	5.0	-2.1	-1.8	1.9	2.0	-1.7	-1.4	-2.2	1.4	1.8	-0.9
Bone: maximum force	9.8	17.0	23.9	-4.8	-4.7	4.7	4.9	-4.6	-3.9	-3.9	3.5	2.9	-2.4
Bone: maximum moment	11.7	20.1	27.7	-5.1	-5.0	4.9	5.3	-4.9	-4.4	-4.3	4.0	3.3	-2.8
Mean time between licks in bursts	0.9	1.3	3.1	1.1	1.2	-0.7	-0.9	1.3	0.9	1.4	-1.0	-1.8	0.6
Mean num. licks in bursts	2.7	3.2	4.8	-1.5	-1.9	0.6	1.5	-2.0	-1.9	-2.2	2.1	1.8	-1.8
Cd content in liver	0.3	0.3	1.0	0.9	1.0	-0.6	-0.6	0.6	0.3	0.5	-0.2	-0.5	-0.1
Co content in liver	0.1	0.1	0.2	-0.1	-0.1	0.1	-0.1	-0.3	-0.2	-0.3	0.4	0.4	-0.4
Cu content in liver	1.4	1.7	2.6	-1.3	-1.2	0.7	1.0	-1.4	-1.6	-1.5	1.3	1.6	-1.0
Fe content in liver	0.5	0.6	1.8	0.9	1.3	-0.8	-1.0	0.8	0.7	0.3	-0.5	-0.1	0.2
K content in liver	0.1	0.1	0.5	-0.0	-0.2	-0.2	-0.2	-0.1	-0.2	0.3	-0.1	-0.7	0.0
Mg content in liver	0.5	0.5	2.0	0.5	0.3	-0.5	-0.6	0.5	0.6	1.0	-0.6	-1.4	0.4
Mn content in liver	0.1	0.1	0.3	-0.3	-0.4	0.3	0.3	-0.2	0.2	0.2	-0.1	-0.6	0.2
Na content in liver	0.2	0.2	0.6	-0.4	-0.6	-0.2	-0.2	-0.8	-0.5	-0.4	0.1	0.3	0.0
Rb content in liver	0.5	0.6	1.8	1.0	1.0	-1.3	-1.1	1.0	0.5	-0.0	-0.1	0.0	-0.3
Se content in liver	1.6	1.9	2.8	1.6	1.7	-1.3	-1.5	1.6	1.2	1.5	-1.1	-1.4	0.6
Sr content in liver	0.9	0.8	1.9	-0.4	-0.3	0.1	0.5	-1.1	-1.0	-1.0	1.2	1.1	-1.4
Zn content in liver	1.5	1.6	2.9	1.7	1.6	-1.5	-1.5	1.4	0.9	1.3	-0.7	-1.2	0.1
Bone: minimum diameter	5.1	9.6	15.0	-3.6	-2.9	3.8	3.9	-3.2	-2.6	-3.2	2.7	2.8	-1.8
Time in familiar zone, hab. session 1	0.5	0.5	2.0	0.1	0.0	0.1	-0.2	0.1	0.4	1.4	-0.6	-1.3	0.5
Time in novel zone, hab. session 1	0.1	0.1	0.4	0.0	0.1	0.0	0.0	0.2	0.4	-0.6	-0.1	0.6	0.2
Total zone transitions, hab. session 1	1.7	2.3	5.1	0.6	0.4	-0.4	-1.2	1.1	2.1	1.6	-2.1	-1.9	2.3
Total locomotion distance, hab. session 1	1.2	1.7	3.2	1.0	1.0	-1.0	-1.2	1.1	1.7	1.2	-1.4	-1.8	1.2
Locomotion velocity, hab. session 1	0.8	1.1	2.6	0.7	0.7	-0.8	-1.0	0.9	1.5	0.9	-1.2	-1.6	1.0
Time in familiar zone, hab. session 2	1.1	1.2	2.1	-1.2	-1.4	1.2	1.3	-1.0	-1.5	-0.3	1.1	0.1	-0.8
Time in novel zone, hab. session 2	1.5	1.5	2.8	1.2	1.4	-1.4	-1.4	1.3	1.7	0.1	-1.2	-0.1	1.0
Total zone transitions, hab. session 2	0.5	0.6	1.4	0.8	0.9	-0.6	-0.8	0.3	1.2	0.4	-0.8	-1.0	0.6
Total locomotion distance, hab. session 2	0.6	0.9	1.6	1.1	1.3	-1.0	-1.0	0.6	1.2	0.4	-0.9	-0.9	0.5
Locomotion velocity, hab. session 2	0.3	0.4	0.9	0.7	0.9	-0.7	-0.7	0.2	0.9	0.2	-0.6	-0.6	0.3
Novel to familiar place preference ratio	0.6	0.6	1.7	-1.1	-1.1	1.3	0.9	-0.6	0.1	-0.4	-0.1	0.5	0.7
Novelty place preference	0.4	0.4	1.1	-0.8	-0.8	1.0	0.6	-0.3	0.3	-0.2	-0.2	0.3	0.7
Time in novel zone, NPP test	0.3	0.3	0.7	-0.6	-0.6	0.8	0.4	-0.1	0.5	-0.0	-0.4	0.2	0.9
Total zone transitions, NPP test	3.1	4.4	7.1	2.1	2.0	-2.1	-2.4	1.5	2.7	2.0	-2.2	-2.3	1.7
Total locomotion distance, NPP test	3.9	5.3	7.0	2.6	2.5	-2.5	-2.6	1.7	2.6	2.3	-2.1	-2.5	1.3
Locomotion velocity, NPP test	2.6	3.7	5.0	2.2	2.1	-2.0	-2.1	1.2	2.2	1.9	-1.7	-2.2	1.0
Intraocular pressure	1.7	2.3	6.8	2.1	1.6	-2.6	-2.0	2.1	0.5	0.4	-0.6	-0.6	-0.1
Delta distance traveled before/after self-admin	1.7	1.9	4.0	-0.9	-0.6	0.7	1.1	-1.8	-1.6	-1.5	1.8	1.0	-2.0
Delta ambulatory time before/after self-admin	1.5	1.7	4.0	-0.6	-0.3	0.4	0.9	-1.7	-1.5	-1.4	1.7	1.1	-2.0
Parametrial fat weight	0.4	0.8	2.3	1.4	1.5	-1.1	-0.8	0.7	0.4	0.2	0.2	-0.9	-0.9
Pavlov. Cond. lever latency	0.2	0.3	0.8	0.7	0.9	-0.8	-0.3	0.4	0.0	0.1	0.4	0.2	-0.8
Pavlov. Cond. magazine entry latency	0.5	0.6	1.5	-1.1	-1.2	1.2	0.9	-0.5	-0.3	-0.5	-0.1	0.4	0.7
Pavlov. Cond. change in total contacts	0.7	0.7	2.0	-1.2	-1.3	1.4	0.9	-0.6	-0.2	-0.4	-0.1	0.0	0.7
Pavlov. Cond. index score	0.6	0.8	2.4	-1.3	-1.6	1.3	0.8	-0.7	-0.3	-0.5	-0.2	0.3	0.8
Pavlov. Cond. latency score	0.6	0.8	2.2	-1.2	-1.5	1.2	0.8	-0.8	-0.2	-0.6	-0.1	0.4	0.7
Pavlov. Cond. lever contacts	0.2	0.3	0.8	-0.7	-0.9	0.7	0.4	-0.6	-0.2	-0.4	-0.1	0.2	0.5
Pavlov. Cond. magazine entry number	0.3	0.4	1.0	0.7	1.0	-0.8	-0.7	0.5	0.6	0.5	-0.2	-0.5	-0.1
Pavlov. Cond. intertrial magazine entries	2.7	3.3	6.5	2.3	2.0	-2.6	-2.4	2.0	1.2	1.3	-1.2	-1.6	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.8	2.3	-1.3	-1.5	1.4	1.0	-0.8	-0.3	-0.5	-0.1	0.2	0.7
Pavlov. Cond. response bias	0.2	0.2	0.7	-0.6	-0.8	0.8	0.6	-0.3	-0.4	-0.3	-0.1	0.2	0.4
Pavlov. Cond. lever latency	0.3	0.4	0.8	-0.8	-0.8	0.8	0.9	-0.4	-0.5	-0.4	0.3	0.7	0.1
Pavlov. Cond. magazine entry latency	0.3	0.4	1.1	0.8	1.1	-0.3	-0.4	0.4	0.4	0.6	-0.1	-0.9	-0.3
Pavlov. Cond. change in total contacts	0.4	0.6	1.5	-1.1	-1.0	1.2	0.5	-0.6	0.4	0.4	-0.4	-0.4	0.8
Pavlov. Cond. index score	0.3	0.4	0.9	0.7	0.9	-0.4	-0.7	0.3	0.6	0.7	-0.3	-0.9	-0.1
Pavlov. Cond. latency score	0.2	0.3	0.7	0.6	0.9	-0.3	-0.7	0.3	0.6	0.6	-0.3	-0.8	-0.1
Pavlov. Cond. lever contacts	0.2	0.3	0.8	0.7	0.9	-0.8	-0.8	0.4	0.3	0.4	-0.1	-0.6	-0.3
Pavlov. Cond. magazine entry number	0.1	0.1	0.6	-0.2	-0.4	-0.1	0.1	-0.1	-0.3	-0.4	0.1	0.7	0.1
Pavlov. Cond. intertrial magazine entries	0.9	1.1	2.8	0.5	0.4	-1.2	-0.3	-0.0	-1.0	-1.0	1.4	1.5	-1.7
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.6	0.3	0.6	-0.1	-0.5	0.2	0.5	0.6	-0.3	-0.8	0.0
Pavlov. Cond. response bias	0.2	0.3	0.8	0.6	0.8	-0.5	-0.6	0.3	0.3	0.6	-0.1	-0.9	-0.4
Time in closed arm before self-admin	0.3	0.3	0.9	-0.9	-0.9	0.9	0.6	-0.3	-0.1	-0.1	-0.2	-0.1	0.6
Time in closed arm after self-admin	0.3	0.3	1.0	-0.5	-0.8	0.6	0.3	0.0	0.4	0.5	-0.6	-0.3	1.0
Time in open arm before self-admin	1.1	1.2	2.6	0.4	0.4	0.0	-0.5	1.2	1.5	1.3	-1.4	-1.1	1.6
Time in open arm after self-admin	0.4	0.4	0.7	0.7	0.8	-0.6	-0.7	0.6	0.6	0.7	-0.6	-0.7	0.4
Bone: periosteal estimation	8.4	17.3	23.2	-4.7	-4.1	4.5	4.8	-4.4	-3.9	-4.5	3.8	3.9	-2.8
Bone: periosteal perimeter	6.9	11.5	16.8	-4.1	-3.8	4.0	4.0	-3.4	-2.8	-3.8	2.6	3.0	-1.5
Bone: post-yield work	6.7	9.1	13.1	-3.4	-3.4	3.2	3.4	-3.6	-3.1	-2.7	2.7	2.4	-1.9
Progressive ratio test 1 active lever presses	3.9	4.1	11.1	3.2	3.3	-3.0	-2.5	1.2	1.3	0.9	-0.7	-0.3	-0.2
Progressive ratio test 1 breakpoint	3.5	3.7	9.9	3.0	3.1	-2.8	-2.3	1.2	1.3	0.9	-0.8	-0.2	-0.1
Progressive ratio test 1 inactive lever presses	1.4	1.5	3.7	1.9	1.8	-1.6	-1.4	0.9	1.1	0.8	-0.9	-0.2	0.4
Progressive ratio test 2 active lever presses	0.8	0.9	2.9	1.6	1.7	-1.3	-1.0	0.2	0.4	-0.0	0.1	0.5	-0.5
Progressive ratio test 2 breakpoint	0.8	0.9	2.9	1.6	1.7	-1.3	-1.0	0.1	0.4	0.0	0.1	0.5	-0.5
Progressive ratio test 2 inactive lever presses	0.7	0.8	2.7	1.5	1.6	-1.1	-0.7	0.1	0.1	-0.4	0.2	0.7	-0.7
Incentive Sensitization - Responses	0.6	0.6	1.0	-0.8	-0.7	0.9	0.8	-0.7	-0.5	-1.0	0.5	1.0	-0.2
Incentive Sensitization - Breakpoint	0.4	0.5	0.9	-0.7	-0.7	0.8	0.7	-0.7	-0.4	-0.9	0.4	0.9	-0.0
Sum of active levers in priming session hrs 5-6	0.8	0.8	1.7	1.1	1.3	-0.8	-0.9	0.4	1.0	0.9	-0.7	-0.8	0.4
Progressive ratio	1.2	1.3	2.5	1.4	1.6	-1.2	-1.2	1.0	1.2	1.0	-0.9	-1.1	0.4
Food seeking constrained by brief footshock	1.0	1.2	2.8	1.6	1.5	-1.7	-1.5	1.1	0.6	0.4	-0.5	-0.7	0.1
Seeking ratio, punishment vs. effort	0.3	0.3	0.7	-0.5	-0.8	0.4	0.5	-0.7	-0.8	-0.6	0.6	0.5	-0.4
Retroperitoneal fat weight	0.4	1.3	3.1	1.8	1.5	-1.4	-1.2	0.4	-0.1	1.2	0.0	-1.2	-0.9
Reaction time number correct	3.4	4.8	8.3	-1.7	-1.7	1.1	2.0	-1.7	-2.5	-2.9	2.6	2.8	-2.3
Reaction time mean minus median	1.7	2.2	5.4	1.8	2.0	-2.3	-2.2	0.9	1.3	0.8	-1.0	-0.3	0.5
Reaction time mean minus median AUC	1.5	2.0	4.2	1.6	1.7	-2.0	-2.0	1.2	1.5	0.9	-1.2	-0.6	0.8
Reaction time num false alarms	2.9	3.9	6.1	2.1	2.0	-1.7	-1.8	2.1	2.5	2.3	-1.8	-1.9	1.4
Reaction time num false alarms AUC	3.8	5.2	8.0	2.3	2.1	-1.9	-2.0	2.5	2.8	2.6	-2.2	-2.3	1.8
Reaction time trials correct on left	3.4	4.8	8.3	-1.7	-1.7	1.1	2.0	-1.7	-2.5	-2.9	2.6	2.8	-2.3
Reaction time trials on left	3.2	4.5	8.0	-1.6	-1.6	0.9	1.9	-1.6	-2.4	-2.8	2.5	2.8	-2.3
Reaction time mean	0.2	0.2	0.5	0.3	0.6	-0.6	-0.5	0.4	-0.2	-0.4	0.1	0.7	-0.3
Reaction time mean AUC	0.1	0.2	0.7	0.0	0.3	-0.4	-0.3	0.2	-0.4	-0.5	0.3	0.8	-0.4
Median of all reaction times	0.2	0.3	0.9	-0.3	0.0	0.2	0.2	0.1	-0.8	-0.8	0.5	0.9	-0.5
Reaction time omissions	3.0	4.1	10.2	2.6	2.6	-3.2	-2.8	1.7	1.9	0.8	-1.2	-0.6	0.4
Reaction time false alarm rate	6.2	8.6	14.0	2.5	2.4	-1.8	-2.5	2.8	3.7	3.7	-3.2	-3.3	2.8
Reaction time premature initiation rate	1.6	2.1	5.4	2.2	1.9	-2.3	-2.0	1.0	0.6	0.9	-0.4	-0.9	-0.2
Reaction time premature initiations	0.7	1.1	2.7	1.1	0.8	-1.6	-0.8	-0.0	-0.9	-0.8	1.0	0.8	-1.5
Std. dev. reaction times	1.8	2.6	5.3	1.9	2.0	-2.3	-2.3	1.3	1.5	1.0	-1.3	-0.7	0.8
Reaction time trials completed	3.2	4.5	8.0	-1.6	-1.6	0.9	1.9	-1.6	-2.4	-2.8	2.5	2.8	-2.3
Reaction time trials AUC	3.6	5.2	8.9	-2.0	-1.9	1.3	2.2	-1.8	-2.5	-3.0	2.6	2.9	-2.3
Run reversals in cocaine runway, females	0.9	0.9	1.3	-0.8	-0.7	0.5	0.9	-0.9	-1.1	-1.1	1.1	1.2	-1.0
Run reversals in cocaine runway, males	1.0	0.9	1.9	0.7	0.4	-1.0	-1.1	1.1	1.2	0.8	-1.2	-0.2	1.4
Latency to leave start box in cocaine runway	1.6	1.7	3.6	0.7	0.6	-0.2	-0.8	1.4	1.5	1.7	-1.5	-1.9	1.6
Latency to leave start box in cocaine runway, F	5.2	5.6	7.7	2.2	2.0	-1.6	-2.1	2.6	2.8	2.7	-2.6	-2.5	2.4
Latency to leave start box in cocaine runway, M	1.4	1.4	3.2	-1.8	-1.5	1.7	1.4	-0.7	-1.2	-0.8	0.8	0.1	-0.5
Std. dev. time between licks in bursts	1.0	1.2	2.2	1.3	1.3	-1.2	-1.3	1.0	0.8	1.5	-0.8	-1.1	0.3
Total sessions with >9 infusions	0.8	0.9	3.2	1.5	1.8	-1.3	-1.0	0.8	0.7	0.1	-0.3	0.1	-0.1
Short access day 1 total inactive lever presses	0.8	0.9	2.4	1.4	1.5	-1.1	-1.0	1.0	0.6	0.4	-0.5	-0.6	0.0
Short access day 10 total inactive lever presses	0.5	0.5	0.9	-0.4	-0.3	0.4	0.6	-0.6	-0.8	-0.9	0.9	1.0	-0.9
Short access day 1 total infusions	0.4	0.5	2.0	0.9	1.4	-0.7	-0.5	0.0	0.1	-0.4	0.3	0.7	-0.6
Short access day 10 total infusions	2.0	2.2	7.9	2.2	2.8	-2.0	-1.6	1.0	1.0	0.6	-0.6	-0.1	-0.1
Short access total infusions	1.1	1.3	5.3	1.7	2.3	-1.5	-1.0	0.7	0.3	-0.0	0.1	0.4	-0.7
Short access day 1 locomotion	0.2	0.3	0.7	0.8	0.8	-0.3	-0.4	0.1	0.7	0.6	-0.4	-0.2	0.3
Short access day 10 total locomotion	0.2	0.2	0.6	0.5	0.8	-0.5	-0.2	0.3	0.4	-0.2	-0.1	0.6	-0.1
Short access total locomotion	0.5	0.6	1.7	1.1	1.3	-0.9	-0.7	0.7	0.6	0.6	-0.5	0.1	0.2
One hour access (0.3 mA shock)	0.2	0.2	0.7	-0.3	-0.0	0.5	0.4	0.2	-0.4	-0.8	0.5	0.7	-0.4
Compulsive drug intake	0.7	0.7	2.2	-1.3	-1.2	1.5	1.1	0.1	-0.2	-0.1	0.0	-0.1	0.4
One hour access (shock baseline)	0.4	0.5	1.6	-0.1	0.1	0.1	0.3	-0.5	-0.7	-1.0	0.7	1.3	-0.7
Social response proportion	1.0	1.1	2.1	-0.4	-0.3	0.3	0.4	-1.4	-1.4	-1.3	1.3	1.0	-1.4
Social responses	2.1	2.7	4.7	2.0	2.1	-2.0	-2.2	1.4	1.7	1.1	-1.3	-1.1	0.8
Social time	1.2	1.6	2.8	-1.0	-0.7	0.8	1.0	-1.4	-1.3	-1.7	1.6	1.0	-1.6
Soleus weight	0.9	2.7	4.8	-2.1	-2.1	1.8	1.8	-2.2	-1.3	-1.3	1.3	1.0	-0.8
Bone: stiffness	11.7	18.4	27.9	-5.3	-5.0	5.3	5.2	-4.6	-3.8	-3.9	3.3	3.2	-2.0
Tibialis anterior weight	1.4	4.8	12.4	-3.0	-3.2	3.5	2.1	-0.5	0.5	-0.7	-1.3	0.3	3.1
Time to tail flick, vehicle, before self-admin	0.8	0.8	1.9	0.8	0.9	-0.9	-0.9	1.4	0.8	0.9	-0.9	-0.6	0.7
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.6	-0.6	-0.4	0.8	0.7	0.2	-0.3	-0.6	0.1	0.4	0.1
Time to tail flick, test, before self-admin	0.7	0.6	1.3	0.2	-0.2	-0.7	-0.8	1.2	0.8	0.6	-1.0	-0.8	1.1
Time to tail flick, test, after self-admin	1.3	1.3	2.3	-1.2	-1.3	0.9	1.1	-0.9	-1.5	-1.2	1.1	1.2	-0.9
Delta time to tail flick, vehicle, before/after SA	1.3	1.3	2.4	-0.9	-0.8	1.1	1.2	-1.1	-1.1	-1.5	1.2	1.2	-1.0
Delta time to tail flick, test, before/after SA	1.4	1.2	1.6	-0.9	-0.6	1.1	1.2	-1.2	-1.3	-1.1	1.2	1.1	-1.1
Tibia length	5.0	14.2	18.2	-3.9	-3.4	3.9	4.3	-3.8	-4.1	-4.0	3.8	3.4	-3.0
Ambulatory time before self-admin	2.5	2.6	4.6	2.1	1.8	-2.0	-1.9	1.6	1.3	1.8	-1.0	-1.0	0.6
Ambulatory time after self-admin	0.6	0.7	1.8	1.1	1.2	-1.3	-0.9	-0.0	-0.0	0.4	0.4	0.1	-1.0
Bone: tissue strength	0.8	0.8	2.4	-1.2	-1.6	1.2	1.1	-1.0	-0.5	-0.3	0.4	-0.1	0.0
Total heroin consumption	1.7	2.0	2.9	-1.4	-1.2	1.3	1.6	-1.6	-1.5	-1.0	1.7	1.1	-1.6
Bone: trabecular number	4.6	7.2	9.7	-2.9	-3.0	2.3	2.8	-3.1	-2.5	-2.9	2.6	2.4	-2.1
Bone: trabecular spacing	1.1	1.5	2.4	1.2	1.2	-0.9	-1.3	1.5	1.3	1.0	-1.4	-0.9	1.2
Bone: trabecular thickness	0.3	0.3	0.7	-0.8	-0.8	0.6	0.5	-0.4	-0.2	-0.8	0.0	0.3	0.3
Bone: trabecular tissue density	1.3	1.9	5.6	0.0	0.0	0.7	-0.3	0.8	1.6	1.5	-2.0	-1.7	2.4
Water consumed over 24 hours	0.8	1.0	2.7	0.1	0.1	-0.2	0.5	-1.2	-1.1	-0.9	1.4	1.0	-1.7
Number of responses in last shaping day	0.1	0.1	0.4	-0.2	-0.3	0.5	0.4	0.3	-0.6	-0.0	0.3	-0.0	-0.2