Hub : Genes

Cdk5rap3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Cdk5rap3 0.4 0.18 9.7e-08 0.24 0.23 0.17 0.22 2.4e-06 3.2e-06 7.8e-05 6.5e-06
2 PL mRNA stability Cdk5rap3 0.07 0.04 2.9e-10 0.08 0.08 0.05 0.09 2.9e-09 7.7e-09 1.7e-06 1.3e-09
3 Adipose mRNA stability Cdk5rap3 0.12 0.07 0.0e+00 0.16 0.17 0.17 0.17 7.7e-17 2.5e-18 3.1e-18 1.8e-18
4 Brain mRNA stability Cdk5rap3 0.3 0.11 0.0e+00 0.34 0.36 0.35 0.36 3.8e-33 6.3e-35 7.3e-34 2.0e-34
5 Adipose gene expression Cdk5rap3 0.03 0.02 1.9e-04 0.03 0.03 0.03 0.03 4.9e-04 2.7e-04 3.6e-04 4.0e-04
6 Brain isoform ratio XM_039086923.1 0.02 0.02 3.8e-03 0.01 0.02 0.02 0.02 2.1e-02 4.2e-03 1.1e-02 8.7e-03
7 BLA mRNA stability Cdk5rap3 0.16 0.11 9.4e-05 0.07 0.06 0.05 0.06 2.1e-04 4.3e-04 9.2e-04 2.2e-04
8 IL mRNA stability Cdk5rap3 0.29 0.14 2.5e-05 0.05 0.13 0.1 0.1 2.1e-02 5.5e-04 1.9e-03 2.4e-03
9 pVTA gene expression Cdk5rap3 0.15 0.09 1.6e-07 0.12 0.14 0.13 0.13 8.1e-06 1.3e-06 2.5e-06 3.1e-06
10 Liver gene expression Cdk5rap3 0.08 0.05 4.4e-10 0.09 0.09 0.08 0.09 1.1e-09 7.0e-10 2.0e-09 4.7e-10
11 LHb alternative TSS NM_024488.2 0.23 0.16 4.1e-03 0.06 0.06 0.04 0.05 1.7e-02 1.8e-02 3.9e-02 2.3e-02
12 NAcc mRNA stability Cdk5rap3 0.07 0.05 6.8e-09 0.06 0.07 0.07 0.07 4.7e-08 1.4e-08 2.9e-08 3.0e-08
13 Liver mRNA stability Cdk5rap3 0.22 0.1 0.0e+00 0.29 0.3 0.3 0.3 6.6e-32 3.2e-34 8.5e-34 4.4e-34
14 PL gene expression Cdk5rap3 0.06 0.04 7.4e-09 0.09 0.08 0.09 0.09 7.3e-10 6.6e-09 1.1e-09 2.5e-10
15 Brain gene expression Cdk5rap3 0.16 0.08 0.0e+00 0.2 0.21 0.21 0.21 3.9e-18 6.2e-19 5.7e-19 6.2e-19
16 OFC mRNA stability Cdk5rap3 0.27 0.17 4.8e-04 0.11 0.1 0.09 0.1 1.3e-03 2.9e-03 3.6e-03 2.2e-03
17 BLA gene expression Cdk5rap3 0.17 0.09 7.4e-10 0.18 0.17 0.16 0.18 4.4e-10 1.9e-09 3.8e-09 7.9e-10
18 NAcc gene expression Cdk5rap3 0.14 0.06 0.0e+00 0.2 0.21 0.2 0.22 1.1e-22 2.7e-24 6.8e-23 9.9e-25
19 Eye gene expression Cdk5rap3 0.33 0.18 8.0e-03 -0 -0.02 -0.02 0 3.8e-01 7.3e-01 8.8e-01 3.0e-01
20 pVTA mRNA stability Cdk5rap3 0.06 0.05 2.3e-03 0.06 0.05 0.04 0.05 1.2e-03 2.4e-03 8.7e-03 3.5e-03
21 RMTg gene expression Cdk5rap3 0.22 0.14 3.6e-05 0.15 0.13 0.17 0.15 6.9e-05 2.7e-04 2.8e-05 9.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.32.32.9-1.61.51.51.51.5-1.6-1.41.61.51.6-1.41.41.41.6-1.5-1.6-1.41.7-1.6-1.7-0.6
Area under the delay curve0.30.30.70.6-0.5-0.4-0.3-0.60.60.6-0.5-0.6-0.50.6-0.8-0.6-0.50.60.50.3-0.60.7-0.10.1
BMI with tail12.038.943.2-6.66.36.46.46.4-6.3-6.36.16.56.4-6.36.56.46.2-6.3-6.2-6.16.1-6.0-6.0-5.1
BMI without tail1.53.14.3-1.61.71.71.91.6-1.6-1.81.61.81.8-1.81.61.71.8-1.8-1.8-1.81.9-1.7-1.7-2.1
Body weight0.52.05.6-1.51.51.52.11.2-1.0-1.30.81.81.3-1.41.31.50.9-1.4-1.3-1.41.4-1.0-0.6-2.4
Weight adjusted by age0.80.91.81.4-0.9-1.0-1.0-1.01.00.7-1.0-1.0-1.00.7-0.9-0.9-1.10.90.80.9-0.91.01.10.4
Bone surface0.30.50.9-0.90.60.70.90.7-0.6-0.40.60.80.9-0.50.60.71.0-0.7-0.8-0.60.9-0.7-0.8-0.6
Bone volume1.11.82.4-1.41.31.31.51.3-1.3-1.21.31.41.5-1.21.31.31.5-1.4-1.5-1.31.5-1.3-1.5-1.1
Breakpoint value in progressive ratio session4.55.05.92.2-2.4-2.3-2.3-2.32.42.3-2.4-2.2-2.22.3-2.2-2.3-2.02.32.12.4-2.32.11.91.9
Number of licking bursts0.10.10.20.5-0.3-0.4-0.4-0.30.20.3-0.2-0.4-0.30.3-0.3-0.3-0.20.30.40.3-0.20.20.20.5
Context. condit. distance diff. score0.20.30.6-0.30.40.40.50.5-0.5-0.50.40.60.5-0.50.60.50.5-0.5-0.4-0.40.7-0.8-0.6-0.6
Locomotion velocity, session 10.50.51.0-0.80.70.70.70.8-0.8-0.80.70.80.6-0.80.90.80.3-0.8-0.8-0.60.9-0.5-0.6-1.0
Locomotion distance, session 12.43.14.91.8-1.6-1.6-1.5-1.81.81.7-1.9-1.6-1.91.7-1.6-1.6-2.21.71.61.7-1.92.02.20.7
Locomotion velocity, session 20.80.91.60.9-0.9-0.9-0.7-1.11.10.9-1.1-0.9-1.10.9-1.0-0.9-1.30.90.81.0-0.91.11.1-0.0
Locomotion distance, session 23.04.25.92.0-1.9-1.9-1.7-2.12.12.0-2.1-1.9-2.22.0-2.0-2.0-2.42.01.92.1-2.12.42.41.2
Locomotion velocity, session 30.00.00.20.0-0.1-0.10.0-0.20.20.1-0.2-0.1-0.10.1-0.2-0.2-0.10.20.10.1-0.30.20.40.1
Locomotion distance, session 33.13.44.31.8-1.8-1.8-1.6-1.91.91.9-2.0-1.8-1.81.9-1.9-1.8-1.81.92.01.9-1.81.82.11.2
Stereotopy head waving bouts, day 34.25.06.2-2.42.22.22.22.3-2.3-2.32.42.12.3-2.32.12.22.2-2.3-2.3-2.32.4-2.1-2.5-1.2
Stereotopy head waving duration, day 33.23.84.7-2.21.91.92.02.0-2.0-2.12.01.91.9-2.11.91.91.7-2.0-2.1-1.92.0-1.7-2.0-1.4
Locomotion velocity, session 71.51.72.31.2-1.2-1.2-1.1-1.31.31.2-1.4-1.2-1.31.2-1.3-1.3-1.41.31.21.2-1.51.41.51.2
Locomotion distance, session 75.16.57.22.5-2.5-2.5-2.4-2.62.62.6-2.6-2.5-2.52.6-2.7-2.6-2.42.62.72.5-2.62.52.72.1
Stereotopy head waving bouts, day 70.60.71.1-0.70.80.80.60.8-0.9-0.90.90.70.9-0.90.80.81.1-0.8-0.9-0.80.8-1.0-1.0-0.6
Stereotopy head waving duration, day 70.30.30.6-0.50.50.50.30.6-0.6-0.60.60.50.7-0.60.60.50.8-0.5-0.7-0.60.4-0.7-0.7-0.3
Locomotion velocity, session 80.10.10.5-0.30.30.30.40.3-0.2-0.30.10.50.1-0.30.50.4-0.1-0.3-0.3-0.30.2-0.1-0.1-0.7
Locomotion distance, session 80.60.91.81.1-0.9-0.9-0.7-1.01.01.0-1.1-0.7-1.11.0-0.8-0.8-1.40.90.90.9-0.91.11.20.2
Degree of sensitization distance0.00.00.00.0-0.1-0.1-0.0-0.10.10.0-0.1-0.1-0.10.0-0.1-0.1-0.10.1-0.00.1-0.20.20.10.2
Degree of sensitization stereotypy0.10.10.30.4-0.3-0.3-0.5-0.10.10.2-0.1-0.40.00.2-0.2-0.30.30.20.20.2-0.3-0.2-0.10.4
Conditioned locomotion1.01.22.2-1.21.11.01.21.1-1.1-1.11.11.11.1-1.01.01.11.2-1.1-1.0-1.21.2-1.5-1.0-0.8
Cocaine response after cond. corrected6.06.79.3-2.52.62.52.72.5-2.5-2.52.62.52.7-2.42.32.52.8-2.7-2.6-2.72.8-3.1-2.7-2.1
Cocaine response after cond. not corrected3.43.75.7-1.82.01.92.11.8-1.8-1.81.91.82.0-1.81.61.82.1-2.0-1.9-2.02.1-2.4-2.0-1.4
Cocaine response before conditioning2.42.93.41.6-1.7-1.7-1.7-1.71.71.7-1.6-1.8-1.71.7-1.9-1.8-1.71.71.71.7-1.71.71.71.6
Saline control response0.30.42.00.1-0.6-0.6-0.6-0.50.50.6-0.4-0.6-0.50.6-0.6-0.6-0.50.60.40.5-0.70.60.51.4
Bone: connectivity density0.10.20.7-0.40.20.30.20.4-0.4-0.20.50.20.6-0.20.20.20.9-0.3-0.3-0.30.5-0.7-0.70.5
Bone: cortical apparent density6.78.913.93.2-3.1-3.1-3.3-2.92.83.0-2.7-3.2-2.93.0-2.9-3.0-2.52.93.13.1-2.82.32.53.7
Bone: cortical area0.00.00.3-0.20.20.30.40.1-0.1-0.10.20.20.1-0.10.10.2-0.1-0.3-0.2-0.10.30.2-0.1-0.5
Bone: cortical porosity0.50.61.1-0.70.80.80.70.7-0.8-0.70.80.60.9-0.80.60.71.0-0.7-0.6-0.80.7-1.0-0.6-0.7
Bone: cortical porosity0.40.40.7-0.60.80.70.70.6-0.6-0.60.70.50.8-0.70.40.60.8-0.6-0.6-0.70.5-0.8-0.5-0.7
Bone: cortical thickness0.30.40.70.6-0.6-0.6-0.5-0.70.60.7-0.6-0.7-0.70.8-0.8-0.7-0.80.60.60.7-0.50.70.70.8
Bone: cortical thickness1.21.42.30.9-1.1-1.2-1.0-1.21.21.3-1.1-1.3-1.11.4-1.5-1.3-1.01.11.21.1-1.00.91.11.3
Bone: cortical tissue density7.09.314.23.3-3.2-3.2-3.4-3.02.93.1-2.8-3.3-3.03.1-3.0-3.1-2.63.03.13.2-2.92.42.53.8
Condit. Reinf. active minus inactive responses0.10.10.30.6-0.4-0.4-0.4-0.30.30.3-0.3-0.4-0.20.3-0.3-0.30.00.30.40.4-0.20.20.10.2
Condit. Reinf. active-inactive response ratio0.20.30.8-0.20.40.50.40.5-0.5-0.50.50.40.6-0.50.40.40.9-0.5-0.5-0.30.5-0.7-0.8-0.4
Condit. Reinf. active responses0.10.10.20.4-0.3-0.3-0.4-0.20.20.4-0.2-0.3-0.10.4-0.3-0.30.10.30.40.3-0.10.10.10.3
Condit. Reinf. inactive responses0.30.40.80.5-0.6-0.7-0.7-0.60.60.8-0.5-0.7-0.50.8-0.6-0.6-0.40.60.90.6-0.40.40.60.8
Incentive salience index mean0.30.30.80.9-0.6-0.5-0.7-0.50.50.5-0.4-0.7-0.50.5-0.6-0.6-0.30.50.60.7-0.50.50.40.4
Condit. Reinf. lever presses0.91.21.91.4-1.1-1.0-1.2-1.01.01.0-0.9-1.2-1.01.0-1.1-1.1-0.91.01.11.3-1.21.11.11.0
Condit. Reinf. active minus inactive responses0.10.10.3-0.30.50.50.40.4-0.5-0.50.50.30.3-0.50.30.40.2-0.4-0.5-0.30.2-0.2-0.20.1
Condit. Reinf. active-inactive response ratio0.40.50.7-0.60.80.80.60.8-0.8-0.70.80.60.6-0.70.70.70.5-0.7-0.7-0.60.5-0.8-0.5-0.3
Condit. Reinf. active responses0.00.00.30.00.10.10.00.1-0.1-0.10.2-0.1-0.0-0.1-0.00.0-0.1-0.1-0.1-0.0-0.00.20.10.5
Condit. Reinf. inactive responses0.30.41.70.4-0.6-0.6-0.6-0.50.50.4-0.4-0.7-0.60.5-0.7-0.6-0.50.60.50.5-0.50.90.51.3
Condit. Reinf. lever presses0.70.91.30.9-0.9-0.9-0.9-0.90.90.9-0.9-1.0-1.00.9-0.9-0.9-1.10.90.90.9-1.01.01.11.0
Condit. Reinf. lever reinforcers received0.10.10.70.2-0.1-0.1-0.2-0.20.10.2-0.1-0.3-0.30.2-0.3-0.2-0.30.20.20.2-0.30.50.40.8
Conditioned reinforcement - actives1.41.42.0-1.01.31.21.01.2-1.3-1.21.31.01.2-1.31.11.21.4-1.2-1.0-1.21.2-1.4-1.2-1.0
Conditioned reinforcement - inactives0.70.82.20.7-0.9-0.8-1.0-0.80.70.7-0.6-1.0-0.70.9-0.9-1.0-0.80.90.60.8-1.10.91.21.5
Conditioned locomotion4.55.46.7-1.82.62.52.32.4-2.4-2.42.52.22.2-2.52.32.52.2-2.5-2.5-2.32.2-2.2-1.8-2.3
Patch foraging indifference point 0 sec1.01.62.0-0.91.31.31.31.2-1.2-1.31.31.11.3-1.31.01.21.4-1.4-1.4-1.31.3-1.2-1.3-1.3
Patch foraging indifference point AUC0.10.10.30.2-0.4-0.4-0.5-0.30.40.3-0.4-0.4-0.30.4-0.3-0.4-0.30.50.40.3-0.50.50.20.2
Delay disc. indifference point, 0s delay1.01.11.70.8-1.0-1.0-1.0-1.11.11.1-1.0-1.2-1.01.1-1.3-1.2-0.91.21.10.9-1.31.20.51.1
Delay disc. indifference point, 16s delay0.30.30.6-0.60.50.60.80.5-0.5-0.40.50.50.5-0.40.30.50.4-0.5-0.5-0.60.6-0.4-0.5-0.1
Delay disc. indifference point, 2s delay0.30.30.80.4-0.4-0.4-0.3-0.60.60.3-0.5-0.7-0.40.3-0.9-0.7-0.60.50.40.4-0.80.80.40.9
Delay disc. indifference point, 24s delay0.40.40.90.9-0.6-0.7-0.5-0.70.70.7-0.7-0.5-0.60.7-0.6-0.5-0.50.60.70.5-0.40.50.4-0.2
Delay disc. indifference point, 4s delay3.53.75.61.8-1.9-1.9-1.6-2.12.12.0-2.1-2.0-1.82.0-2.4-2.1-1.82.01.91.8-2.12.01.10.9
Delay disc. indifference point, 8s delay0.10.10.20.4-0.2-0.2-0.2-0.30.30.4-0.3-0.4-0.20.4-0.5-0.3-0.20.30.40.1-0.20.3-0.5-0.3
Indifference point function ln k0.00.10.50.20.20.10.20.0-0.00.10.10.10.1-0.00.00.20.1-0.20.1-0.20.3-0.30.1-0.7
Indifference point function log k0.00.10.50.20.20.10.20.0-0.00.10.10.10.1-0.00.00.20.1-0.20.1-0.20.3-0.30.1-0.7
Patch foraging total patch changes 0 sec1.01.62.1-1.01.31.21.31.2-1.2-1.31.31.11.3-1.31.01.21.5-1.3-1.4-1.31.3-1.2-1.3-1.3
Patch foraging total patch changes 12 sec0.20.30.8-0.30.50.40.40.5-0.5-0.60.70.30.6-0.50.30.40.9-0.5-0.4-0.70.6-0.8-0.8-0.1
Patch foraging total patch changes 18 sec1.51.92.2-1.41.51.51.31.5-1.5-1.51.51.31.4-1.41.41.41.5-1.3-1.4-1.51.2-1.2-1.2-0.8
Patch foraging total patch changes 24 sec1.72.13.5-1.41.31.41.31.3-1.4-1.51.41.31.6-1.41.21.31.9-1.4-1.7-1.41.3-1.5-1.7-1.5
Patch foraging total patch changes 6 sec0.91.41.7-0.91.31.21.11.2-1.2-1.21.31.11.2-1.21.11.21.3-1.2-1.1-1.31.2-1.1-1.1-0.9
Patch foraging time to switch 0 sec0.10.10.2-0.20.20.20.20.4-0.4-0.30.40.30.3-0.40.40.30.3-0.3-0.3-0.30.4-0.5-0.4-0.0
Patch foraging water rate 0 sec0.61.01.6-1.21.11.11.30.9-0.9-1.00.81.11.0-0.90.81.00.9-1.0-1.1-1.11.0-0.9-0.9-1.2
Patch foraging water rate 12 sec0.10.10.40.3-0.2-0.3-0.1-0.40.50.4-0.5-0.3-0.30.3-0.5-0.4-0.30.30.40.4-0.40.40.6-0.5
Patch foraging water rate 18 sec0.50.71.30.6-0.8-0.8-0.7-1.00.90.9-0.9-1.0-0.70.9-1.1-1.0-0.60.90.70.9-1.00.60.90.7
Patch foraging water rate 24 sec0.60.81.3-1.10.90.91.00.8-0.8-0.80.90.80.9-0.80.70.80.9-0.9-0.9-1.00.8-1.0-0.7-0.6
Patch foraging water rate 6 sec0.10.10.3-0.2-0.3-0.2-0.3-0.20.20.3-0.2-0.3-0.10.3-0.4-0.4-0.20.30.10.2-0.40.20.30.6
Seeking ratio, delayed vs. immediate footshock0.30.30.8-0.60.50.40.40.6-0.6-0.30.60.60.6-0.30.70.60.6-0.5-0.4-0.60.9-0.9-0.10.3
Distance traveled before self-admin0.50.51.10.6-0.6-0.6-0.6-0.70.70.7-0.7-0.8-0.80.7-0.8-0.8-0.90.80.60.7-1.01.00.40.2
Distance traveled after self-admin1.71.96.1-0.91.51.41.31.2-1.2-1.31.21.41.4-1.31.31.41.6-1.3-0.9-1.41.2-1.5-1.5-2.5
Extensor digitorum longus weight0.10.64.6-0.60.80.81.00.5-0.4-0.60.11.10.4-0.60.90.8-0.0-0.5-0.5-0.60.4-0.00.2-2.1
Bone: elastic displacement0.20.20.4-0.50.50.50.50.4-0.5-0.60.50.40.3-0.60.40.50.2-0.5-0.5-0.30.4-0.2-0.3-0.5
Bone: elastic work0.00.00.3-0.00.20.20.30.1-0.1-0.10.10.2-0.0-0.10.00.2-0.2-0.2-0.0-0.10.20.10.2-0.6
Bone: endosteal estimation0.40.94.4-0.80.90.91.10.8-0.7-0.80.61.10.9-0.80.90.90.9-0.9-0.8-0.91.0-0.7-0.8-2.1
Bone: endosteal perimeter0.51.13.5-0.91.01.01.11.0-0.9-1.00.81.21.0-1.01.01.00.9-1.0-1.0-1.01.1-0.7-1.1-1.9
Epididymis fat weight0.00.00.2-0.00.20.20.30.0-0.0-0.1-0.00.2-0.1-0.20.00.1-0.4-0.10.20.00.10.20.4-0.3
Delta time in closed arm before/after self-admin0.10.11.50.5-0.1-0.1-0.2-0.10.20.2-0.30.0-0.00.10.10.00.20.10.40.10.0-0.2-0.6-1.2
Delta time in open arm before/after self-admin0.30.30.60.3-0.5-0.5-0.5-0.40.40.3-0.4-0.5-0.50.3-0.4-0.5-0.60.50.40.4-0.70.60.70.7
Diff in mean of infusions in LGA sessions0.60.61.20.7-1.0-0.9-1.0-0.80.81.0-0.8-0.8-0.51.1-0.8-0.9-0.10.91.00.9-0.60.30.10.5
Delay discount exponential model param0.30.40.8-0.70.50.50.30.7-0.7-0.60.60.60.5-0.60.90.70.6-0.6-0.6-0.40.6-0.80.00.1
Extinction: sum of active levers before priming0.90.91.91.4-1.0-1.2-0.9-1.01.01.0-1.1-0.9-1.00.9-0.9-0.9-0.81.01.00.8-0.90.70.8-0.3
Active lever presses in extinction session 60.10.10.5-0.30.30.30.30.4-0.4-0.30.40.40.3-0.30.40.40.2-0.4-0.4-0.20.3-0.2-0.7-0.6
Bone: final force0.20.30.5-0.50.60.70.70.5-0.5-0.40.60.50.6-0.40.40.50.4-0.6-0.5-0.60.7-0.6-0.4-0.6
Bone: final moment0.20.40.7-0.60.70.80.80.6-0.6-0.50.70.60.7-0.50.40.60.5-0.7-0.6-0.70.8-0.7-0.5-0.6
Food consumed during 24 hour testing period1.21.51.91.4-1.3-1.3-1.3-1.31.31.3-1.3-1.2-1.31.3-1.1-1.2-1.21.21.31.3-1.21.01.20.3
Glucose0.40.61.4-1.01.00.91.20.8-0.8-0.80.80.80.8-0.70.50.80.6-0.9-0.7-1.00.9-0.5-0.5-0.3
Heart weight1.21.73.1-1.81.21.41.51.3-1.2-1.21.11.51.2-1.21.31.30.7-1.3-1.5-1.21.2-0.8-1.2-1.6
Delay discount hyperbolic model param0.60.61.3-0.90.70.70.50.9-0.9-0.80.90.90.7-0.81.10.90.8-0.8-0.8-0.60.9-1.0-0.2-0.3
Intermittent access intake day 1-15 change2.32.33.1-1.71.61.71.61.6-1.6-1.71.51.51.6-1.71.41.51.3-1.5-1.5-1.51.2-1.2-1.1-1.2
Intermittent access intake escalation2.42.43.2-1.71.71.71.71.6-1.6-1.81.61.51.7-1.71.51.51.5-1.5-1.5-1.51.2-1.3-1.1-1.3
Intermittent access intake escalation 21.81.82.9-1.71.41.51.51.4-1.4-1.41.31.41.4-1.41.31.31.2-1.2-1.3-1.31.0-1.0-1.1-1.0
Intermitt. access day 1 inactive lever presses0.50.62.90.0-0.7-0.5-0.7-0.50.50.7-0.5-0.7-0.60.8-0.7-0.8-0.70.70.60.7-0.70.81.01.7
Intermitt. access day 15 inactive lever presses0.30.31.6-1.00.30.40.10.6-0.6-0.30.70.30.6-0.20.50.30.5-0.5-0.6-0.40.4-0.6-0.81.3
Intermitt. access escalation Index3.12.75.9-0.71.61.41.61.4-1.4-1.41.41.61.6-1.41.61.72.0-1.6-1.4-1.81.8-1.9-2.1-2.4
Intermittent access day 1 total infusions0.20.30.80.9-0.5-0.6-0.6-0.50.50.6-0.5-0.5-0.60.6-0.5-0.4-0.20.50.80.3-0.30.20.3-0.1
Intermittent access day 15 total infusions0.30.30.7-0.30.60.50.50.5-0.5-0.60.60.40.6-0.50.50.50.7-0.5-0.3-0.60.4-0.6-0.5-0.8
Intermittent access terminal intake (last 3 days)0.20.20.6-0.40.50.40.40.5-0.5-0.40.50.40.5-0.40.50.50.7-0.4-0.3-0.50.4-0.6-0.7-0.4
Intermittent access total infusions0.00.00.40.10.10.10.00.1-0.1-0.00.10.10.2-0.00.10.10.4-0.10.0-0.20.2-0.3-0.3-0.7
Intermittent access day 1 locomotion0.20.20.40.6-0.4-0.5-0.5-0.40.40.5-0.3-0.5-0.50.5-0.4-0.4-0.20.40.40.3-0.40.20.50.1
Intermittent access day 15 total locomotion0.30.30.5-0.50.60.60.50.6-0.6-0.50.60.50.5-0.50.60.60.5-0.6-0.6-0.60.6-0.5-0.4-0.7
Intermittent access total locomotion0.60.71.1-0.60.90.90.80.9-0.9-0.81.00.80.8-0.80.80.90.8-0.9-0.9-0.90.9-0.8-0.8-1.0
Intermittent access standard deviation1.81.93.7-1.91.41.51.51.4-1.4-1.51.41.41.5-1.31.21.31.2-1.3-1.6-1.41.0-1.2-1.3-0.8
Left kidney weight0.10.21.50.0-0.2-0.10.5-0.40.50.4-0.60.1-0.40.4-0.4-0.2-0.80.10.20.20.00.70.6-1.2
Right kidney weight0.30.93.7-1.01.01.01.40.7-0.7-0.80.61.10.7-0.80.70.90.4-1.0-0.9-0.91.0-0.5-0.4-1.9
Cocaine induced anxiety0.10.10.3-0.30.30.30.30.2-0.2-0.10.10.40.2-0.10.40.30.1-0.2-0.4-0.30.0-0.1-0.5-0.5
Post-drug Anxiety0.60.71.50.5-0.8-0.8-0.9-0.70.70.9-0.7-0.8-0.81.0-0.6-0.8-0.90.90.70.8-0.91.00.61.2
Baseline Anxiety0.20.22.7-0.1-0.3-0.2-0.4-0.10.00.20.1-0.4-0.10.2-0.2-0.3-0.10.20.30.3-0.20.30.31.7
Tail length9.829.637.56.1-5.6-5.6-5.0-5.96.05.5-6.0-5.4-5.65.4-5.9-5.5-5.25.45.55.3-5.25.25.62.4
Length with tail6.624.030.85.2-4.8-4.9-4.0-5.35.45.0-5.5-4.5-5.14.9-5.1-4.8-5.34.85.04.7-4.75.15.62.1
Length without tail0.30.72.00.6-0.5-0.6-0.3-0.80.90.9-1.0-0.4-0.90.8-0.7-0.6-1.40.71.00.7-0.71.21.40.1
Times rat made contact with spout0.00.00.20.4-0.3-0.3-0.4-0.20.20.2-0.1-0.3-0.20.2-0.2-0.2-0.10.20.10.3-0.10.1-0.00.2
Lifetime Intake0.00.00.30.3-0.1-0.1-0.2-0.10.10.2-0.0-0.1-0.00.2-0.0-0.00.30.10.2-0.10.0-0.2-0.1-0.6
Liver weight, left1.01.53.20.9-1.2-1.1-1.1-1.21.21.2-1.2-1.1-1.41.2-1.2-1.2-1.81.21.21.3-1.21.61.20.9
Liver weight, right1.32.23.50.9-1.4-1.4-1.0-1.51.61.6-1.6-1.4-1.51.6-1.7-1.5-1.91.41.61.3-1.31.61.61.4
Locomotor activity0.71.12.1-0.80.90.80.71.0-1.1-0.91.10.91.1-0.91.11.01.4-1.0-1.0-1.11.1-1.5-1.3-0.5
Locomotor testing distance1.21.93.6-1.21.31.20.91.4-1.5-1.31.61.11.5-1.31.41.31.9-1.3-1.4-1.41.4-1.9-1.7-0.5
Locomotor testing rearing0.10.10.3-0.60.00.1-0.20.3-0.3-0.10.4-0.10.3-0.10.10.00.6-0.1-0.3-0.10.1-0.5-0.60.6
Locomotion in novel chamber0.81.02.10.8-1.0-1.0-1.0-1.01.01.1-0.9-1.1-0.91.1-1.2-1.1-0.80.91.11.1-0.90.80.41.5
Locomotion in novel chamber post-restriction1.62.02.8-1.01.51.51.21.5-1.5-1.71.61.31.3-1.71.51.51.3-1.4-1.3-1.31.3-1.2-1.5-0.8
Fecal boli incidents, locomotor time 12.62.85.2-2.31.61.61.71.8-1.7-1.71.71.81.6-1.71.81.71.5-1.7-1.8-1.61.7-1.4-1.6-1.0
Change in fecal boli incidents, locomotor task2.22.13.41.9-1.4-1.4-1.5-1.61.61.4-1.5-1.6-1.51.4-1.6-1.5-1.31.51.61.3-1.51.31.20.6
Time >=10cm from walls, locomotor time 10.20.20.50.7-0.5-0.6-0.7-0.40.40.5-0.3-0.5-0.30.5-0.4-0.40.10.40.50.2-0.20.0-0.4-0.3
Bouts of movement, locomotor time 10.00.10.2-0.5-0.00.00.30.2-0.1-0.10.10.30.0-0.10.20.2-0.1-0.3-0.2-0.10.5-0.00.30.4
Total resting periods, locomotor time 10.10.10.5-0.70.20.20.50.3-0.3-0.30.20.50.2-0.30.30.3-0.0-0.4-0.3-0.20.6-0.20.20.4
Rest time, locomotor task time 10.20.20.6-0.80.40.40.60.4-0.4-0.60.40.50.3-0.60.30.4-0.1-0.5-0.4-0.50.5-0.2-0.50.0
Distance moved, locomotor task time 10.91.01.61.3-1.1-1.1-1.1-1.11.11.1-1.1-1.1-0.81.1-1.1-1.1-0.31.01.01.0-1.00.70.30.8
Vertical activity count, locomotor time 10.20.21.01.0-0.4-0.5-0.6-0.50.50.3-0.5-0.5-0.30.3-0.4-0.40.30.40.50.3-0.40.00.4-0.3
Time >=10cm from walls, locomotor time 20.60.60.90.9-0.8-0.9-0.9-0.80.70.7-0.7-0.9-0.70.7-0.9-0.8-0.50.70.80.8-0.60.60.81.0
Bouts of movement, locomotor time 20.10.10.4-0.60.20.30.30.3-0.3-0.30.40.30.3-0.30.30.30.2-0.3-0.3-0.10.4-0.3-0.20.1
Total resting periods, locomotor time 20.10.10.4-0.70.30.40.30.4-0.4-0.30.40.30.3-0.30.30.30.2-0.3-0.3-0.20.4-0.2-0.30.0
Rest time, locomotor task time 21.11.31.80.9-1.3-1.3-1.3-1.11.11.3-1.1-1.1-1.31.3-0.9-1.1-1.31.21.21.1-1.01.20.50.7
Distance moved, locomotor task time 20.10.10.40.6-0.1-0.10.1-0.40.40.1-0.4-0.2-0.20.1-0.4-0.20.00.20.10.2-0.30.20.30.1
Vertical activity count, locomotor time 20.20.20.90.30.50.50.60.2-0.2-0.70.20.30.5-0.70.10.40.8-0.4-0.4-0.40.3-0.6-0.1-0.9
Light reinforcement 10.40.71.3-1.10.80.80.50.9-1.0-0.71.10.60.8-0.70.80.81.0-0.8-0.9-0.70.8-0.7-0.90.2
Light reinforcement 20.10.10.5-0.10.20.20.10.2-0.3-0.30.30.10.4-0.30.20.20.7-0.3-0.2-0.30.3-0.6-0.5-0.1
Bone: marrow area0.30.73.8-0.60.70.70.90.6-0.6-0.60.50.90.8-0.70.70.80.7-0.7-0.7-0.80.9-0.6-0.7-2.0
Bone: maximum diameter0.50.92.2-0.91.01.01.00.9-0.9-0.80.90.91.0-0.80.80.90.9-0.9-0.9-0.91.0-0.7-0.9-1.5
Bone: maximum force0.61.02.7-0.91.01.01.20.9-0.9-0.70.91.00.9-0.70.81.00.7-1.1-0.9-1.01.2-0.9-0.8-1.6
Bone: maximum moment0.61.12.7-1.01.11.11.30.9-0.9-0.80.91.11.0-0.80.81.00.7-1.1-0.9-1.01.2-1.0-0.7-1.6
Mean time between licks in bursts0.10.10.2-0.10.40.40.40.4-0.3-0.40.30.40.2-0.40.50.40.2-0.3-0.3-0.40.3-0.1-0.2-0.4
Mean num. licks in bursts0.00.00.10.1-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.20.2-0.3-0.2-0.20.20.10.3-0.30.20.20.2
Cd content in liver0.70.81.30.8-1.0-1.0-1.0-0.90.90.8-0.8-0.9-0.80.8-0.9-0.9-0.60.90.91.0-0.81.00.71.2
Co content in liver0.00.00.2-0.40.10.10.20.1-0.1-0.10.00.20.2-0.10.20.10.3-0.1-0.1-0.10.2-0.2-0.2-0.1
Cu content in liver1.72.03.11.4-1.6-1.5-1.6-1.51.51.5-1.5-1.4-1.31.5-1.3-1.5-1.11.61.81.5-1.40.91.40.7
Fe content in liver1.31.62.21.1-1.3-1.2-1.0-1.31.41.4-1.4-1.1-1.31.4-1.3-1.3-1.31.31.31.3-1.21.11.50.7
K content in liver0.20.20.4-0.50.30.40.50.3-0.3-0.40.40.40.5-0.40.30.30.6-0.3-0.3-0.30.4-0.6-0.4-0.2
Mg content in liver0.80.81.10.9-0.9-0.9-0.9-0.80.80.9-0.8-0.9-0.70.9-0.9-0.9-0.70.91.00.9-0.90.70.81.1
Mn content in liver2.32.63.71.7-1.8-1.7-1.9-1.61.51.5-1.5-1.7-1.61.5-1.5-1.7-1.31.71.51.8-1.71.51.31.7
Na content in liver0.91.01.5-1.00.90.90.81.0-1.0-0.91.00.91.1-0.91.00.91.1-0.9-1.1-0.90.8-1.2-1.1-0.8
Rb content in liver0.20.32.60.2-0.2-0.2-0.4-0.20.10.4-0.1-0.4-0.30.4-0.3-0.4-0.50.40.50.3-0.40.40.61.6
Se content in liver0.10.10.3-0.50.30.40.40.4-0.4-0.40.40.30.4-0.40.20.20.2-0.3-0.4-0.30.4-0.1-0.40.6
Sr content in liver1.71.52.41.5-1.3-1.3-1.2-1.41.41.0-1.4-1.3-1.31.0-1.3-1.2-1.21.21.11.3-1.31.41.10.3
Zn content in liver0.10.10.6-0.10.10.10.00.2-0.2-0.30.3-0.00.2-0.30.00.10.2-0.1-0.20.0-0.1-0.3-0.10.8
Bone: minimum diameter0.10.11.3-0.10.30.30.50.2-0.1-0.20.10.40.2-0.20.20.30.0-0.3-0.3-0.30.40.1-0.1-1.1
Time in familiar zone, hab. session 10.60.51.00.7-0.8-0.8-1.0-0.60.60.8-0.6-0.8-0.70.8-0.6-0.7-0.50.70.90.8-0.50.50.41.0
Time in novel zone, hab. session 13.03.03.5-1.81.81.81.81.7-1.7-1.91.81.71.7-1.91.61.71.7-1.7-1.9-1.81.6-1.7-1.6-1.2
Total zone transitions, hab. session 16.49.010.43.0-3.0-3.0-2.9-3.03.03.1-3.1-2.9-3.13.1-2.9-2.9-3.13.03.03.0-3.13.13.22.2
Total locomotion distance, hab. session 12.84.05.41.9-2.0-1.9-1.9-1.91.92.1-1.9-2.0-2.12.1-1.9-2.0-2.32.02.02.0-1.92.22.11.8
Locomotion velocity, hab. session 13.75.27.02.2-2.2-2.2-2.1-2.32.32.4-2.3-2.2-2.42.4-2.2-2.2-2.62.22.22.3-2.22.62.51.8
Time in familiar zone, hab. session 20.30.30.8-0.90.50.60.40.6-0.7-0.60.70.50.6-0.60.60.50.6-0.5-0.5-0.40.5-0.6-0.60.3
Time in novel zone, hab. session 20.10.10.20.4-0.2-0.2-0.1-0.30.30.2-0.2-0.2-0.20.2-0.3-0.2-0.30.20.20.1-0.20.30.2-0.0
Total zone transitions, hab. session 21.72.22.91.7-1.5-1.5-1.5-1.51.51.5-1.5-1.4-1.61.5-1.3-1.4-1.61.51.51.6-1.51.51.50.7
Total locomotion distance, hab. session 20.00.10.50.2-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.30.1-0.1-0.1-0.70.10.10.2-0.10.60.3-0.0
Locomotion velocity, hab. session 20.10.10.60.3-0.2-0.2-0.1-0.20.20.2-0.2-0.2-0.40.2-0.2-0.2-0.80.20.20.3-0.10.70.4-0.1
Novel to familiar place preference ratio0.80.81.31.0-1.0-1.0-0.8-1.01.11.0-1.1-0.8-0.91.0-0.9-0.9-0.71.01.00.8-0.80.70.80.2
Novelty place preference1.01.01.41.1-1.0-1.1-0.9-1.11.11.1-1.2-0.9-1.01.1-1.0-1.0-0.81.01.10.9-0.90.80.90.4
Time in novel zone, NPP test0.80.81.11.0-0.9-1.0-0.8-1.01.01.0-1.0-0.8-0.81.0-1.0-0.9-0.60.91.00.8-0.80.60.80.5
Total zone transitions, NPP test3.55.06.92.3-2.1-2.1-2.1-2.22.22.1-2.2-2.2-2.42.1-2.2-2.2-2.62.22.02.3-2.52.42.61.5
Total locomotion distance, NPP test0.91.32.70.9-1.0-0.9-1.0-1.01.01.0-1.0-1.1-1.31.0-1.1-1.1-1.71.10.91.1-1.31.61.51.0
Locomotion velocity, NPP test1.52.14.01.2-1.3-1.2-1.2-1.41.41.3-1.4-1.3-1.61.3-1.4-1.3-2.01.41.21.4-1.62.01.81.0
Intraocular pressure1.01.42.01.3-1.2-1.2-1.2-1.31.41.4-1.4-1.1-1.01.4-1.2-1.2-0.61.21.41.3-0.90.91.0-0.0
Delta distance traveled before/after self-admin3.23.56.5-1.21.91.81.71.8-1.8-1.81.71.91.9-1.82.02.02.2-1.8-1.3-1.91.9-2.2-1.6-2.5
Delta ambulatory time before/after self-admin3.23.54.6-1.32.01.81.81.8-1.8-1.91.81.91.9-1.91.92.02.1-1.9-1.4-1.91.9-2.1-1.4-2.1
Parametrial fat weight0.10.10.90.40.10.10.10.2-0.2-0.10.30.10.4-0.00.10.20.8-0.3-0.0-0.20.5-1.0-0.5-0.5
Pavlov. Cond. lever latency1.51.92.9-1.31.41.31.51.3-1.2-1.21.11.61.3-1.21.41.41.2-1.4-1.2-1.51.6-1.3-1.3-1.7
Pavlov. Cond. magazine entry latency0.00.10.40.2-0.1-0.1-0.3-0.0-0.10.10.2-0.30.00.1-0.2-0.10.3-0.00.10.10.1-0.2-0.30.6
Pavlov. Cond. change in total contacts2.12.33.21.6-1.6-1.6-1.8-1.51.41.6-1.2-1.7-1.41.6-1.6-1.6-1.01.51.61.6-1.41.11.11.8
Pavlov. Cond. index score0.50.61.80.9-0.8-0.8-1.0-0.70.60.7-0.4-1.1-0.70.7-0.9-0.8-0.40.70.70.8-0.80.60.51.4
Pavlov. Cond. latency score0.60.81.81.0-0.9-0.8-1.1-0.80.70.8-0.6-1.1-0.80.8-1.0-0.9-0.60.80.80.9-0.90.80.71.3
Pavlov. Cond. lever contacts1.92.22.91.7-1.5-1.4-1.7-1.41.41.4-1.3-1.7-1.41.4-1.5-1.5-1.21.51.41.6-1.61.31.41.5
Pavlov. Cond. magazine entry number0.20.31.4-0.60.50.50.80.3-0.2-0.50.00.80.3-0.50.50.50.1-0.4-0.4-0.50.4-0.2-0.0-1.2
Pavlov. Cond. intertrial magazine entries0.50.61.00.6-0.8-0.8-0.7-0.80.80.8-0.9-0.7-0.70.8-0.7-0.8-0.70.81.00.7-0.60.70.90.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.50.9-0.7-0.7-1.0-0.60.60.6-0.4-1.0-0.60.6-0.8-0.8-0.30.70.60.8-0.70.40.41.2
Pavlov. Cond. response bias0.50.61.80.9-0.8-0.8-1.1-0.70.60.8-0.4-1.1-0.60.8-0.9-0.8-0.30.70.80.8-0.80.50.51.3
Pavlov. Cond. lever latency0.50.71.31.2-0.9-0.9-0.9-0.90.90.9-0.9-0.8-0.80.9-0.9-0.9-0.80.91.00.9-0.80.70.7-0.1
Pavlov. Cond. magazine entry latency0.50.50.90.6-0.7-0.7-0.6-0.80.80.6-0.8-0.7-0.80.7-0.8-0.7-0.80.70.60.8-0.71.00.80.6
Pavlov. Cond. change in total contacts0.20.30.5-0.60.60.50.50.6-0.6-0.50.60.40.4-0.50.50.50.4-0.5-0.6-0.70.4-0.1-0.40.1
Pavlov. Cond. index score0.20.30.5-0.70.60.50.70.5-0.6-0.60.60.50.5-0.60.50.60.5-0.6-0.7-0.60.5-0.1-0.4-0.2
Pavlov. Cond. latency score0.10.10.3-0.50.40.30.50.3-0.3-0.40.30.30.3-0.40.30.40.3-0.4-0.5-0.40.3-0.0-0.2-0.1
Pavlov. Cond. lever contacts0.40.61.1-1.00.80.80.80.8-0.8-0.80.90.70.7-0.80.70.80.7-0.8-0.9-0.80.7-0.6-0.70.2
Pavlov. Cond. magazine entry number0.00.00.10.1-0.1-0.0-0.20.00.00.1-0.0-0.00.10.10.1-0.00.00.10.10.1-0.1-0.3-0.1-0.2
Pavlov. Cond. intertrial magazine entries1.92.54.31.6-1.5-1.5-1.6-1.51.51.6-1.6-1.5-1.61.6-1.4-1.5-1.71.61.71.6-1.62.11.71.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.6-0.80.70.60.80.6-0.6-0.70.60.60.5-0.70.60.70.5-0.7-0.8-0.70.6-0.1-0.4-0.3
Pavlov. Cond. response bias0.40.61.0-1.00.80.80.80.8-0.8-0.80.90.70.7-0.80.70.80.7-0.8-0.9-0.80.7-0.6-0.60.1
Time in closed arm before self-admin0.80.92.2-1.51.01.11.11.0-1.0-1.01.10.80.9-1.00.80.80.4-0.9-1.3-0.90.5-0.3-0.11.1
Time in closed arm after self-admin0.50.50.8-0.90.70.80.80.7-0.7-0.70.60.70.8-0.70.70.70.7-0.7-0.7-0.60.5-0.7-0.5-0.4
Time in open arm before self-admin0.20.32.51.1-0.1-0.3-0.4-0.30.30.4-0.4-0.1-0.30.40.0-0.00.10.20.70.10.1-0.2-0.3-1.6
Time in open arm after self-admin0.40.41.11.0-0.6-0.8-0.9-0.60.60.6-0.6-0.6-0.80.5-0.4-0.5-0.70.70.90.5-0.60.60.5-0.3
Bone: periosteal estimation0.40.82.8-0.80.90.91.10.8-0.8-0.80.81.00.9-0.70.80.90.7-0.9-0.8-0.91.0-0.6-0.8-1.7
Bone: periosteal perimeter0.40.61.7-0.80.70.80.90.7-0.6-0.70.60.90.8-0.70.70.70.6-0.7-0.8-0.70.8-0.4-0.8-1.3
Bone: post-yield work0.20.20.8-0.30.30.30.50.4-0.3-0.10.30.60.4-0.10.40.50.4-0.5-0.3-0.40.8-0.7-0.4-0.9
Progressive ratio test 1 active lever presses0.10.11.01.0-0.1-0.3-0.3-0.30.30.3-0.2-0.3-0.30.2-0.3-0.1-0.00.20.40.10.00.0-0.0-0.6
Progressive ratio test 1 breakpoint0.20.31.11.1-0.4-0.6-0.5-0.60.50.5-0.4-0.6-0.60.4-0.6-0.4-0.30.40.60.4-0.20.30.3-0.2
Progressive ratio test 1 inactive lever presses0.00.00.1-0.00.10.20.10.2-0.2-0.10.30.10.1-0.10.10.10.2-0.2-0.2-0.20.3-0.2-0.10.0
Progressive ratio test 2 active lever presses0.00.10.30.6-0.2-0.2-0.4-0.20.20.2-0.1-0.3-0.20.2-0.2-0.1-0.00.20.30.1-0.10.1-0.0-0.2
Progressive ratio test 2 breakpoint0.00.00.20.5-0.0-0.1-0.2-0.10.10.10.0-0.2-0.10.1-0.1-0.00.10.00.2-0.00.00.0-0.0-0.4
Progressive ratio test 2 inactive lever presses0.10.10.20.0-0.4-0.3-0.5-0.30.30.5-0.3-0.4-0.30.5-0.3-0.4-0.20.40.30.4-0.40.30.20.3
Incentive Sensitization - Responses0.00.00.1-0.30.10.20.10.2-0.2-0.10.30.10.2-0.10.10.10.1-0.2-0.2-0.10.10.0-0.20.1
Incentive Sensitization - Breakpoint0.10.10.2-0.50.30.40.30.4-0.4-0.30.50.30.4-0.30.30.30.3-0.4-0.5-0.30.3-0.2-0.3-0.1
Sum of active levers in priming session hrs 5-63.33.24.22.1-2.0-2.0-2.0-1.91.91.9-1.8-1.9-1.72.0-1.9-1.9-1.41.81.71.9-1.81.31.10.9
Progressive ratio0.50.63.8-0.3-0.6-0.5-0.4-0.60.50.5-0.6-0.6-0.60.5-0.7-0.8-1.10.70.20.9-0.91.20.62.0
Food seeking constrained by brief footshock0.60.81.5-1.20.91.00.90.9-0.9-0.61.00.90.9-0.60.80.90.8-0.9-0.9-0.71.0-0.8-0.9-0.8
Seeking ratio, punishment vs. effort0.70.96.00.30.70.60.50.6-0.6-0.40.70.70.8-0.40.80.91.3-0.8-0.2-0.91.2-1.4-0.9-2.5
Retroperitoneal fat weight0.31.12.6-1.31.31.31.61.0-1.0-1.10.91.20.9-1.10.81.00.3-1.2-0.9-1.11.2-0.6-0.5-0.8
Reaction time number correct0.20.30.7-0.2-0.4-0.3-0.3-0.40.40.5-0.5-0.4-0.50.5-0.4-0.5-0.70.50.20.6-0.80.70.80.8
Reaction time mean minus median0.30.41.51.2-0.5-0.7-0.9-0.50.50.7-0.5-0.6-0.70.7-0.4-0.4-0.30.61.00.2-0.30.30.40.4
Reaction time mean minus median AUC0.50.61.91.4-0.7-0.9-1.1-0.60.60.8-0.5-0.8-0.80.8-0.5-0.6-0.40.71.10.4-0.50.50.60.9
Reaction time num false alarms0.20.20.50.6-0.4-0.4-0.6-0.50.50.4-0.4-0.6-0.50.4-0.6-0.5-0.30.50.40.6-0.70.30.50.1
Reaction time num false alarms AUC0.20.30.70.6-0.5-0.5-0.7-0.60.60.5-0.5-0.7-0.50.5-0.7-0.6-0.30.60.50.7-0.90.40.60.2
Reaction time trials correct on left0.20.30.7-0.2-0.4-0.3-0.3-0.40.40.5-0.5-0.4-0.50.5-0.4-0.5-0.70.50.20.6-0.80.70.80.8
Reaction time trials on left0.20.30.7-0.1-0.4-0.3-0.3-0.40.40.5-0.5-0.4-0.50.6-0.4-0.5-0.70.50.20.6-0.80.70.80.7
Reaction time mean0.10.20.40.60.20.0-0.20.3-0.3-0.10.30.20.1-0.20.50.40.6-0.30.2-0.60.6-0.5-0.5-0.4
Reaction time mean AUC0.10.10.60.80.2-0.1-0.20.2-0.2-0.10.30.20.0-0.10.50.40.4-0.20.3-0.50.6-0.4-0.5-0.5
Median of all reaction times0.30.40.90.10.60.50.20.7-0.7-0.60.70.60.5-0.60.80.70.8-0.7-0.3-0.80.9-0.8-1.0-0.5
Reaction time omissions0.00.00.20.40.0-0.2-0.20.0-0.00.20.1-0.1-0.10.20.00.10.1-0.10.3-0.20.4-0.1-0.2-0.2
Reaction time false alarm rate0.00.00.30.5-0.1-0.2-0.3-0.20.1-0.0-0.1-0.3-0.1-0.0-0.2-0.20.20.10.20.1-0.2-0.20.0-0.3
Reaction time premature initiation rate0.30.40.90.9-0.5-0.7-0.6-0.70.70.5-0.6-0.7-0.60.4-0.7-0.6-0.30.60.80.5-0.50.60.50.5
Reaction time premature initiations0.60.81.10.9-0.8-0.9-0.9-1.01.00.8-0.9-1.0-0.90.8-1.0-0.9-0.80.90.90.9-1.01.01.10.8
Std. dev. reaction times0.10.21.11.0-0.3-0.5-0.6-0.30.30.5-0.3-0.4-0.50.5-0.2-0.2-0.20.30.7-0.1-0.10.20.30.1
Reaction time trials completed0.20.30.7-0.1-0.4-0.3-0.3-0.40.40.5-0.5-0.4-0.50.6-0.4-0.5-0.70.50.20.6-0.80.70.80.7
Reaction time trials AUC0.20.30.7-0.1-0.4-0.3-0.4-0.40.40.6-0.5-0.4-0.50.6-0.5-0.5-0.70.60.30.7-0.80.70.90.7
Run reversals in cocaine runway, females0.20.21.60.7-0.3-0.3-0.2-0.40.40.3-0.5-0.2-0.20.3-0.3-0.2-0.00.30.40.3-0.20.1-0.3-1.3
Run reversals in cocaine runway, males0.70.61.1-0.50.90.80.51.0-1.0-0.91.00.70.7-0.91.10.90.5-0.8-0.9-0.80.6-0.6-0.8-0.4
Latency to leave start box in cocaine runway2.52.74.0-2.01.61.71.81.7-1.6-1.61.51.81.8-1.61.71.71.6-1.6-1.6-1.61.6-1.7-1.2-1.2
Latency to leave start box in cocaine runway, F4.04.35.7-2.42.22.32.42.1-2.1-2.12.02.32.1-2.12.22.21.7-2.0-2.0-2.11.9-1.9-1.6-1.8
Latency to leave start box in cocaine runway, M0.60.61.5-1.00.50.60.70.7-0.7-0.60.70.91.0-0.60.80.71.2-0.8-0.7-0.51.0-1.1-0.7-0.4
Std. dev. time between licks in bursts1.21.51.7-1.31.21.21.21.3-1.2-1.31.21.31.2-1.31.31.31.2-1.2-1.2-1.31.2-1.0-1.2-1.1
Total sessions with >9 infusions0.50.51.7-0.10.80.70.60.6-0.7-0.70.70.60.6-0.80.60.70.8-0.7-0.5-0.90.9-0.9-0.5-1.3
Short access day 1 total inactive lever presses3.94.37.51.6-2.3-2.1-2.3-2.01.92.2-1.9-2.2-1.92.3-2.1-2.2-1.92.11.82.2-2.12.01.72.7
Short access day 10 total inactive lever presses1.11.24.50.3-1.1-0.9-1.1-0.90.91.1-0.9-1.0-1.01.2-0.9-1.1-1.31.10.91.1-1.11.41.12.1
Short access day 1 total infusions0.00.00.10.0-0.1-0.1-0.2-0.10.10.2-0.0-0.1-0.00.2-0.1-0.10.10.20.20.0-0.1-0.1-0.1-0.1
Short access day 10 total infusions0.40.41.2-0.50.60.60.50.6-0.6-0.60.60.60.6-0.60.60.60.9-0.6-0.5-0.70.7-0.9-0.9-1.1
Short access total infusions0.00.00.4-0.00.10.10.10.1-0.1-0.10.10.10.2-0.10.10.10.4-0.1-0.1-0.20.2-0.4-0.2-0.6
Short access day 1 locomotion0.70.81.6-1.30.91.01.00.9-0.9-1.01.00.80.9-0.90.70.80.8-0.9-1.1-0.90.7-0.9-0.8-0.3
Short access day 10 total locomotion0.40.41.3-0.70.70.70.80.7-0.7-0.70.80.60.5-0.60.50.60.3-0.7-1.1-0.60.5-0.2-0.2-0.2
Short access total locomotion0.80.81.6-1.20.91.01.10.9-0.9-0.91.00.90.8-0.90.80.90.6-0.9-1.3-0.90.8-0.7-0.3-0.5
One hour access (0.3 mA shock)0.60.61.01.0-0.9-0.9-1.0-0.80.80.9-0.8-0.9-0.70.8-0.8-0.8-0.50.80.90.9-0.80.60.50.6
Compulsive drug intake7.27.39.53.1-2.8-2.9-2.8-2.82.82.8-2.8-2.8-2.72.7-2.7-2.7-2.42.73.02.7-2.52.32.22.2
One hour access (shock baseline)2.42.83.4-1.91.71.71.71.7-1.8-1.71.81.71.8-1.71.71.71.8-1.6-1.8-1.71.5-1.6-1.4-1.2
Social response proportion0.70.81.21.0-0.8-0.8-0.7-1.01.00.9-0.9-0.9-0.90.8-1.1-0.9-1.10.80.80.8-0.70.80.80.7
Social responses0.00.00.30.2-0.2-0.2-0.2-0.20.20.2-0.1-0.2-0.40.2-0.2-0.1-0.50.1-0.10.10.10.2-0.00.2
Social time0.00.00.20.1-0.1-0.2-0.30.1-0.10.10.1-0.00.00.10.20.10.3-0.1-0.10.00.2-0.5-0.40.2
Soleus weight0.92.64.6-2.11.81.81.91.7-1.7-1.71.71.61.5-1.71.51.61.1-1.8-1.7-1.61.7-1.2-1.3-0.8
Bone: stiffness0.10.10.7-0.30.30.30.40.2-0.20.10.20.30.30.00.10.20.3-0.3-0.1-0.30.5-0.4-0.1-0.8
Tibialis anterior weight0.30.92.20.9-0.8-0.8-0.8-0.91.00.8-1.1-0.7-1.20.9-0.7-0.8-1.50.91.00.8-0.91.41.4-0.1
Time to tail flick, vehicle, before self-admin2.02.13.71.4-1.8-1.9-1.7-1.51.41.9-1.4-1.5-1.31.9-1.4-1.5-0.81.51.41.5-1.20.80.71.2
Time to tail flick, vehicle, after self-admin0.10.10.6-0.80.40.50.30.4-0.4-0.20.40.30.5-0.20.30.30.5-0.3-0.2-0.20.2-0.4-0.40.4
Time to tail flick, test, before self-admin0.00.00.2-0.3-0.1-0.00.10.1-0.10.00.00.20.10.00.20.10.1-0.1-0.50.10.0-0.0-0.3-0.2
Time to tail flick, test, after self-admin0.20.20.9-0.20.30.20.40.3-0.2-0.20.20.40.3-0.20.30.40.5-0.4-0.2-0.40.6-0.6-0.7-1.0
Delta time to tail flick, vehicle, before/after SA1.41.42.4-1.51.41.51.31.2-1.2-1.31.21.11.2-1.31.11.11.0-1.2-1.2-1.11.0-0.8-0.8-0.4
Delta time to tail flick, test, before/after SA0.10.10.30.5-0.2-0.2-0.2-0.40.40.2-0.3-0.4-0.30.2-0.5-0.3-0.20.30.50.2-0.20.1-0.0-0.1
Tibia length0.31.02.0-1.01.21.11.40.9-0.8-0.90.71.20.8-0.90.91.10.6-1.0-0.7-1.11.1-1.0-0.4-1.4
Ambulatory time before self-admin0.30.30.80.5-0.4-0.3-0.5-0.50.50.4-0.6-0.6-0.60.4-0.6-0.5-0.80.60.40.4-0.90.90.50.1
Ambulatory time after self-admin2.42.67.7-1.01.71.61.71.4-1.4-1.71.31.71.6-1.71.51.71.7-1.5-1.1-1.61.4-1.7-1.2-2.8
Bone: tissue strength0.10.10.3-0.10.30.30.30.4-0.3-0.40.30.40.2-0.40.50.40.0-0.4-0.3-0.20.5-0.3-0.4-0.6
Total heroin consumption1.92.23.01.7-1.6-1.6-1.7-1.41.41.7-1.4-1.5-1.41.7-1.3-1.4-1.31.51.51.5-1.31.21.01.5
Bone: trabecular number0.60.91.4-1.10.91.00.81.0-1.0-0.81.20.71.0-0.80.80.81.1-0.9-0.9-0.91.0-1.0-1.20.2
Bone: trabecular spacing0.00.10.30.2-0.0-0.1-0.2-0.10.1-0.1-0.1-0.1-0.3-0.10.0-0.0-0.50.10.00.1-0.40.50.4-0.2
Bone: trabecular thickness1.51.82.4-1.31.31.41.51.3-1.2-1.31.21.41.4-1.31.21.31.4-1.4-1.4-1.31.5-1.4-1.4-1.4
Bone: trabecular tissue density0.20.21.30.3-0.3-0.3-0.3-0.40.40.3-0.4-0.4-0.70.3-0.4-0.4-1.10.40.20.5-0.60.80.60.4
Water consumed over 24 hours0.20.30.40.6-0.5-0.6-0.6-0.50.50.6-0.5-0.5-0.50.6-0.4-0.5-0.40.50.40.6-0.50.30.40.7
Number of responses in last shaping day0.00.00.40.10.10.0-0.00.2-0.1-0.10.10.10.1-0.00.30.20.1-0.0-0.1-0.20.1-0.1-0.4-0.6