Hub : Genes

Cdc42se2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Cdc42se2 0.46 0.15 1.3e-15 0.1 0.14 0.13 0.1 2.8e-11 8.1e-15 2.7e-14 2.6e-11
2 Brain mRNA stability Cdc42se2 0.03 0.03 7.2e-03 0.01 0.01 0 0.01 1.3e-02 6.3e-02 2.1e-01 3.5e-02
3 IC gene expression Cdc42se2 0.36 0.17 5.6e-17 0.33 0.33 0.33 0.32 2.3e-14 2.0e-14 2.4e-14 3.8e-14
4 Adipose gene expression Cdc42se2 0.07 0.06 4.3e-07 0.04 0.05 0.04 0.04 9.7e-06 7.2e-06 1.2e-05 1.2e-05
5 OFC gene expression Cdc42se2 0.2 0.16 1.1e-03 0.08 0.09 0.09 0.08 6.4e-03 4.6e-03 4.6e-03 4.9e-03
6 PL mRNA stability Cdc42se2 0.02 0.02 7.6e-03 0.02 0.01 0.01 0.02 3.8e-03 8.8e-03 1.9e-02 6.3e-03
7 Liver gene expression Cdc42se2 0.05 0.06 4.5e-03 0.01 0 0.01 0.01 1.4e-02 9.7e-02 2.0e-02 3.1e-02
8 NAcc mRNA stability Cdc42se2 0.03 0.03 2.6e-04 0.02 0.02 0.02 0.02 1.3e-03 3.3e-04 1.6e-03 6.6e-04
9 Brain gene expression Cdc42se2 0.16 0.1 2.5e-15 0.16 0.17 0.14 0.17 9.4e-15 2.3e-15 3.2e-13 2.9e-15
10 PL gene expression Cdc42se2 0.1 0.09 1.6e-09 0.09 0.08 0.08 0.09 7.7e-10 1.7e-09 2.8e-09 6.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.21.1-1.10.3-0.2-0.4-0.30.10.4-0.2-0.2-0.0
Area under the delay curve0.10.10.20.4-0.30.40.40.40.0-0.20.30.30.3
BMI with tail0.00.10.3-0.4-0.30.30.20.3-0.4-0.40.40.40.6
BMI without tail0.21.11.40.9-0.91.01.01.0-1.2-1.21.11.01.1
Body weight0.93.84.11.9-1.82.02.01.9-2.0-2.02.02.02.0
Weight adjusted by age0.00.00.10.2-0.20.10.10.1-0.1-0.10.10.10.2
Bone surface0.00.00.0-0.1-0.20.20.10.1-0.2-0.10.20.20.2
Bone volume0.30.51.6-1.30.7-0.6-0.7-0.70.50.7-0.6-0.6-0.5
Breakpoint value in progressive ratio session0.71.21.6-0.91.1-1.2-1.1-1.20.81.3-1.2-1.1-1.2
Number of licking bursts0.10.20.50.7-0.30.40.40.4-0.5-0.40.40.40.3
Context. condit. distance diff. score0.00.10.1-0.4-0.10.20.10.2-0.3-0.10.20.20.3
Locomotion velocity, session 10.10.10.10.10.3-0.3-0.2-0.20.30.3-0.2-0.2-0.2
Locomotion distance, session 10.30.30.40.5-0.60.50.60.6-0.6-0.60.60.60.6
Locomotion velocity, session 20.80.91.00.9-0.91.01.01.0-1.0-0.91.01.01.0
Locomotion distance, session 20.50.71.41.2-0.80.70.80.8-0.7-0.80.80.80.6
Locomotion velocity, session 32.83.33.71.5-1.81.81.81.9-1.8-1.81.91.91.9
Locomotion distance, session 32.12.42.91.1-1.51.61.61.6-1.6-1.41.61.61.7
Stereotopy head waving bouts, day 30.20.30.50.10.5-0.6-0.5-0.50.70.5-0.6-0.5-0.6
Stereotopy head waving duration, day 31.82.32.8-1.01.5-1.6-1.5-1.61.71.4-1.6-1.5-1.6
Locomotion velocity, session 70.00.00.2-0.4-0.00.0-0.00.0-0.1-0.00.10.10.1
Locomotion distance, session 70.10.10.2-0.30.3-0.4-0.4-0.40.40.3-0.3-0.3-0.4
Stereotopy head waving bouts, day 70.20.20.3-0.40.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5
Stereotopy head waving duration, day 71.11.41.6-0.81.2-1.2-1.2-1.21.31.2-1.2-1.2-1.3
Locomotion velocity, session 82.32.83.31.2-1.61.81.71.7-1.8-1.61.81.71.8
Locomotion distance, session 80.91.31.41.0-1.11.11.11.1-1.1-1.11.21.21.1
Degree of sensitization distance2.93.13.8-1.11.6-1.9-1.8-1.91.91.6-1.8-1.8-1.9
Degree of sensitization stereotypy0.10.10.1-0.20.2-0.2-0.3-0.30.30.2-0.3-0.3-0.3
Conditioned locomotion0.50.61.41.2-0.80.70.80.7-0.7-0.90.70.70.6
Cocaine response after cond. corrected0.10.10.9-0.90.2-0.1-0.3-0.2-0.10.2-0.2-0.2-0.2
Cocaine response after cond. not corrected0.71.12.8-1.70.9-0.9-1.1-1.00.70.8-0.9-1.0-0.9
Cocaine response before conditioning2.32.83.2-1.71.6-1.7-1.7-1.71.81.6-1.7-1.7-1.6
Saline control response1.01.51.7-1.11.0-1.3-1.3-1.31.21.1-1.2-1.2-1.2
Bone: connectivity density0.00.00.2-0.50.2-0.2-0.2-0.20.10.2-0.1-0.1-0.1
Bone: cortical apparent density0.60.91.4-1.21.0-0.9-1.0-0.90.81.0-0.9-0.9-0.8
Bone: cortical area0.61.01.11.1-0.91.01.01.0-1.0-0.91.01.01.0
Bone: cortical porosity0.20.30.40.2-0.40.60.50.5-0.5-0.50.50.50.6
Bone: cortical porosity0.60.61.1-1.00.9-0.7-0.8-0.70.70.8-0.7-0.7-0.7
Bone: cortical thickness0.40.70.80.9-0.80.80.90.9-0.9-0.80.80.90.9
Bone: cortical thickness0.10.10.10.10.3-0.4-0.3-0.30.30.3-0.3-0.3-0.3
Bone: cortical tissue density0.71.21.8-1.31.1-1.1-1.1-1.00.91.1-1.0-1.0-1.0
Condit. Reinf. active minus inactive responses0.30.30.40.3-0.50.50.50.6-0.6-0.50.60.60.6
Condit. Reinf. active-inactive response ratio1.01.11.30.9-1.01.11.11.1-1.1-1.01.11.11.0
Condit. Reinf. active responses0.00.00.1-0.10.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2
Condit. Reinf. inactive responses1.72.22.5-1.21.4-1.6-1.5-1.51.61.5-1.5-1.5-1.6
Incentive salience index mean1.31.71.91.4-1.31.31.31.3-1.3-1.31.31.31.2
Condit. Reinf. lever presses2.84.26.32.5-2.02.02.12.0-1.9-2.12.02.01.8
Condit. Reinf. active minus inactive responses0.50.82.1-1.50.7-0.8-0.9-0.90.80.8-0.8-0.9-0.7
Condit. Reinf. active-inactive response ratio0.00.10.1-0.1-0.30.30.20.2-0.2-0.30.30.20.2
Condit. Reinf. active responses1.72.53.5-1.91.5-1.6-1.6-1.61.51.5-1.5-1.6-1.4
Condit. Reinf. inactive responses3.65.35.6-2.22.3-2.4-2.3-2.32.32.4-2.3-2.3-2.2
Condit. Reinf. lever presses0.20.30.9-1.00.5-0.5-0.6-0.60.40.5-0.5-0.5-0.4
Condit. Reinf. lever reinforcers received1.72.34.1-2.01.4-1.5-1.6-1.51.41.5-1.5-1.5-1.3
Conditioned reinforcement - actives0.00.10.40.50.4-0.10.30.30.40.00.30.40.6
Conditioned reinforcement - inactives0.41.02.8-0.51.7-1.1-0.8-0.81.11.1-0.8-0.8-0.7
Conditioned locomotion0.30.41.0-0.31.0-0.8-0.5-0.50.80.8-0.4-0.4-0.2
Patch foraging indifference point 0 sec2.05.77.1-2.72.3-2.5-2.5-2.42.22.4-2.3-2.3-2.2
Patch foraging indifference point AUC0.00.00.1-0.1-0.30.10.00.0-0.2-0.10.0-0.00.1
Delay disc. indifference point, 0s delay0.00.00.00.1-0.10.00.00.0-0.0-0.00.00.00.0
Delay disc. indifference point, 16s delay0.00.00.1-0.20.0-0.0-0.1-0.10.30.2-0.1-0.10.0
Delay disc. indifference point, 2s delay1.21.41.61.0-1.21.21.21.2-1.0-1.31.21.21.1
Delay disc. indifference point, 24s delay0.00.00.10.2-0.10.30.30.30.0-0.10.20.20.2
Delay disc. indifference point, 4s delay1.31.41.8-0.81.3-1.2-1.1-1.11.31.3-1.2-1.2-1.3
Delay disc. indifference point, 8s delay0.30.40.80.9-0.50.70.70.7-0.3-0.60.70.70.7
Indifference point function ln k0.10.40.70.6-0.50.50.70.7-0.5-0.60.70.80.8
Indifference point function log k0.10.40.70.6-0.50.50.70.7-0.5-0.60.70.80.8
Patch foraging total patch changes 0 sec2.16.17.0-2.62.4-2.6-2.6-2.52.32.5-2.4-2.4-2.3
Patch foraging total patch changes 12 sec5.27.07.5-2.72.5-2.6-2.7-2.72.52.5-2.7-2.7-2.7
Patch foraging total patch changes 18 sec1.02.42.8-1.71.3-1.6-1.7-1.71.21.6-1.7-1.7-1.6
Patch foraging total patch changes 24 sec1.55.07.7-2.81.9-2.1-2.4-2.31.92.2-2.3-2.3-2.2
Patch foraging total patch changes 6 sec3.86.47.1-2.72.5-2.6-2.6-2.62.42.6-2.5-2.5-2.4
Patch foraging time to switch 0 sec0.31.01.4-0.61.2-0.9-0.9-1.01.00.9-1.0-1.0-1.1
Patch foraging water rate 0 sec0.20.91.30.8-1.10.91.01.0-0.8-0.91.01.11.1
Patch foraging water rate 12 sec0.10.50.70.8-0.70.70.70.7-0.6-0.60.70.70.6
Patch foraging water rate 18 sec0.71.52.2-0.91.3-1.2-1.2-1.21.51.2-1.2-1.2-1.4
Patch foraging water rate 24 sec0.40.60.9-0.90.7-0.8-0.8-0.80.80.7-0.7-0.7-0.6
Patch foraging water rate 6 sec1.42.13.51.9-1.41.31.51.5-1.2-1.31.41.51.4
Seeking ratio, delayed vs. immediate footshock0.50.81.5-1.20.7-0.8-0.9-0.90.70.7-0.9-0.9-0.9
Distance traveled before self-admin1.12.32.51.5-1.51.51.61.6-1.4-1.51.61.61.5
Distance traveled after self-admin0.00.00.10.3-0.10.20.20.20.1-0.30.10.1-0.0
Extensor digitorum longus weight0.31.11.3-0.91.0-1.1-1.1-1.11.20.9-1.0-1.1-1.1
Bone: elastic displacement0.00.10.5-0.70.10.1-0.1-0.0-0.20.10.00.00.1
Bone: elastic work0.60.81.00.4-0.91.00.90.9-1.0-0.90.90.91.0
Bone: endosteal estimation0.51.21.61.3-1.11.11.11.1-0.9-1.11.11.11.0
Bone: endosteal perimeter0.81.93.01.7-1.31.31.41.4-1.2-1.41.31.31.3
Epididymis fat weight0.10.61.10.2-0.60.80.70.8-1.0-0.60.80.80.9
Delta time in closed arm before/after self-admin0.20.20.5-0.6-0.7-0.3-0.4-0.40.00.5-0.3-0.3-0.1
Delta time in open arm before/after self-admin0.20.20.50.70.20.50.50.5-0.3-0.60.50.50.4
Diff in mean of infusions in LGA sessions0.00.00.2-0.5-0.20.1-0.1-0.0-0.3-0.10.00.0-0.1
Delay discount exponential model param0.10.10.1-0.40.2-0.3-0.3-0.3-0.10.2-0.3-0.3-0.3
Extinction: sum of active levers before priming0.00.00.10.4-0.40.00.10.1-0.10.00.10.10.1
Active lever presses in extinction session 61.31.31.8-1.31.1-1.2-1.2-1.21.11.1-1.1-1.1-1.1
Bone: final force1.42.32.41.4-1.51.61.51.6-1.5-1.51.51.61.6
Bone: final moment1.42.22.31.4-1.41.51.51.5-1.5-1.51.51.51.5
Food consumed during 24 hour testing period4.18.18.82.6-2.92.92.92.9-3.0-2.92.92.82.8
Glucose0.10.10.10.2-0.30.40.30.3-0.3-0.40.30.30.3
Heart weight1.72.83.51.6-1.31.71.81.8-1.5-1.51.81.81.9
Delay discount hyperbolic model param0.00.00.1-0.20.1-0.1-0.2-0.2-0.20.0-0.1-0.1-0.1
Intermittent access intake day 1-15 change0.21.01.60.01.1-1.0-0.8-0.91.31.0-1.0-1.0-1.0
Intermittent access intake escalation0.21.11.7-0.11.1-1.0-0.9-1.01.31.1-1.1-1.1-1.1
Intermittent access intake escalation 21.22.12.9-0.71.3-1.5-1.4-1.41.71.5-1.6-1.5-1.5
Intermitt. access day 1 inactive lever presses0.00.60.7-0.70.8-0.8-0.7-0.70.70.9-0.7-0.7-0.8
Intermitt. access day 15 inactive lever presses0.00.00.1-0.00.3-0.1-0.1-0.10.10.1-0.1-0.1-0.1
Intermitt. access escalation Index0.10.20.30.1-0.40.30.40.4-0.3-0.30.50.50.6
Intermittent access day 1 total infusions0.10.20.40.6-0.10.20.40.4-0.2-0.20.40.50.5
Intermittent access day 15 total infusions0.10.20.50.50.7-0.5-0.2-0.20.70.5-0.3-0.2-0.1
Intermittent access terminal intake (last 3 days)0.20.30.80.40.8-0.7-0.4-0.40.90.7-0.5-0.4-0.3
Intermittent access total infusions0.10.10.70.80.4-0.10.20.20.30.10.10.20.3
Intermittent access day 1 locomotion0.00.00.20.5-0.0-0.10.10.10.10.10.10.20.3
Intermittent access day 15 total locomotion1.34.96.7-1.52.6-2.4-2.2-2.22.32.4-2.2-2.2-2.0
Intermittent access total locomotion3.13.74.8-1.12.2-2.2-1.9-1.92.12.2-1.9-1.9-1.7
Intermittent access standard deviation0.10.50.90.8-0.80.70.60.6-1.0-0.60.50.60.6
Left kidney weight3.225.728.95.0-5.45.15.15.1-4.9-5.05.15.15.0
Right kidney weight3.021.322.64.4-4.54.84.74.7-4.6-4.74.64.64.5
Cocaine induced anxiety0.10.10.9-0.11.0-0.3-0.2-0.20.40.3-0.2-0.1-0.0
Post-drug Anxiety0.30.30.8-0.30.9-0.7-0.5-0.50.60.7-0.5-0.5-0.4
Baseline Anxiety0.30.51.30.7-1.10.60.60.6-0.8-0.70.60.60.4
Tail length0.84.65.52.4-2.02.22.22.1-2.3-2.12.12.11.9
Length with tail1.15.07.12.7-1.92.22.32.3-2.1-2.32.22.22.1
Length without tail0.21.11.31.2-0.91.01.11.1-0.8-1.01.11.11.2
Times rat made contact with spout1.01.11.31.1-1.01.01.11.1-1.1-1.01.01.01.0
Lifetime Intake0.40.41.71.30.00.40.70.7-0.2-0.30.60.70.8
Liver weight, left0.10.10.2-0.20.3-0.3-0.4-0.40.40.2-0.4-0.4-0.5
Liver weight, right0.00.00.1-0.0-0.10.30.20.2-0.2-0.30.20.20.2
Locomotor activity1.52.43.2-1.51.8-1.6-1.5-1.51.61.5-1.5-1.5-1.5
Locomotor testing distance2.35.68.3-2.92.4-2.3-2.4-2.32.22.2-2.3-2.3-2.2
Locomotor testing rearing1.03.78.3-2.91.7-1.8-2.0-1.91.71.7-1.8-1.8-1.6
Locomotion in novel chamber0.10.10.4-0.00.6-0.2-0.2-0.20.50.1-0.3-0.3-0.3
Locomotion in novel chamber post-restriction0.00.10.2-0.40.1-0.1-0.2-0.20.3-0.1-0.2-0.3-0.2
Fecal boli incidents, locomotor time 10.00.10.4-0.70.3-0.2-0.3-0.3-0.10.1-0.3-0.3-0.5
Change in fecal boli incidents, locomotor task1.21.32.61.6-0.91.21.31.2-0.7-1.11.11.11.2
Time >=10cm from walls, locomotor time 13.03.74.0-1.91.9-1.9-1.9-2.02.01.9-2.0-2.0-2.0
Bouts of movement, locomotor time 10.30.40.6-0.80.8-0.6-0.6-0.60.50.6-0.6-0.6-0.6
Total resting periods, locomotor time 10.30.30.6-0.80.6-0.5-0.6-0.60.40.4-0.5-0.6-0.6
Rest time, locomotor task time 10.30.40.6-0.70.5-0.7-0.7-0.70.60.5-0.7-0.7-0.7
Distance moved, locomotor task time 10.00.10.30.5-0.10.20.30.30.0-0.00.30.30.5
Vertical activity count, locomotor time 10.10.50.8-0.60.9-0.6-0.6-0.60.90.7-0.6-0.6-0.5
Time >=10cm from walls, locomotor time 20.00.00.1-0.3-0.00.0-0.0-0.0-0.2-0.10.00.00.0
Bouts of movement, locomotor time 20.10.20.5-0.00.7-0.4-0.3-0.30.60.3-0.4-0.4-0.3
Total resting periods, locomotor time 20.00.20.4-0.10.7-0.4-0.3-0.40.60.3-0.4-0.4-0.3
Rest time, locomotor task time 21.42.32.4-1.51.4-1.5-1.5-1.51.51.5-1.5-1.5-1.5
Distance moved, locomotor task time 20.00.00.1-0.30.2-0.2-0.1-0.10.10.3-0.1-0.10.2
Vertical activity count, locomotor time 20.00.10.2-0.30.4-0.3-0.3-0.20.30.3-0.2-0.2-0.0
Light reinforcement 10.52.43.3-1.81.4-1.5-1.6-1.61.31.5-1.5-1.5-1.4
Light reinforcement 20.00.00.1-0.2-0.00.20.00.0-0.0-0.30.10.10.2
Bone: marrow area0.61.51.91.4-1.21.21.31.2-1.1-1.21.21.21.2
Bone: maximum diameter1.42.93.41.8-1.61.71.71.7-1.6-1.71.71.71.7
Bone: maximum force0.51.01.11.0-1.01.01.01.0-0.9-1.01.01.01.0
Bone: maximum moment0.50.91.01.0-0.90.91.01.0-0.9-1.00.90.90.9
Mean time between licks in bursts0.63.43.71.7-1.81.91.81.9-1.9-1.81.81.81.8
Mean num. licks in bursts0.00.10.2-0.40.2-0.2-0.2-0.20.30.2-0.2-0.2-0.2
Cd content in liver1.71.92.5-1.01.3-1.5-1.4-1.41.61.3-1.4-1.4-1.4
Co content in liver0.10.10.80.9-0.00.00.30.20.1-0.10.20.30.2
Cu content in liver0.00.00.10.30.00.10.20.10.1-0.10.10.20.2
Fe content in liver0.00.00.0-0.00.10.10.10.1-0.00.10.10.10.2
K content in liver11.811.513.13.6-3.53.43.43.4-3.3-3.53.33.33.2
Mg content in liver2.42.63.51.9-1.71.61.61.6-1.4-1.71.61.61.5
Mn content in liver0.10.10.20.50.1-0.3-0.2-0.30.30.1-0.3-0.3-0.4
Na content in liver1.41.61.91.4-1.31.31.31.2-1.2-1.21.21.21.2
Rb content in liver1.72.03.7-1.91.5-1.3-1.4-1.31.31.5-1.3-1.3-1.1
Se content in liver1.51.82.01.3-1.21.41.41.4-1.3-1.31.41.41.4
Sr content in liver0.00.00.20.4-0.3-0.00.0-0.00.1-0.2-0.0-0.0-0.1
Zn content in liver0.60.70.80.9-0.80.80.80.8-0.7-0.80.80.80.8
Bone: minimum diameter1.01.92.51.6-1.31.31.41.4-1.3-1.31.41.41.4
Time in familiar zone, hab. session 17.58.39.8-3.12.9-2.9-2.9-2.82.83.0-2.8-2.8-2.6
Time in novel zone, hab. session 14.75.25.82.0-2.32.42.32.3-2.4-2.42.32.32.2
Total zone transitions, hab. session 10.10.10.1-0.20.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3
Total locomotion distance, hab. session 10.50.80.9-0.70.8-1.0-0.9-0.91.00.8-0.9-0.9-0.9
Locomotion velocity, hab. session 10.10.20.40.10.4-0.5-0.4-0.40.60.4-0.5-0.5-0.5
Time in familiar zone, hab. session 21.51.71.8-1.21.3-1.3-1.3-1.31.21.3-1.3-1.3-1.3
Time in novel zone, hab. session 23.33.64.01.6-1.91.91.91.9-2.0-1.92.02.02.0
Total zone transitions, hab. session 20.10.10.2-0.1-0.20.30.20.2-0.4-0.30.30.30.3
Total locomotion distance, hab. session 20.20.30.5-0.70.6-0.5-0.5-0.50.40.6-0.5-0.5-0.4
Locomotion velocity, hab. session 20.00.00.1-0.30.3-0.2-0.2-0.20.10.3-0.2-0.2-0.1
Novel to familiar place preference ratio0.20.20.3-0.40.4-0.5-0.5-0.50.50.4-0.5-0.5-0.6
Novelty place preference0.10.10.2-0.30.3-0.4-0.4-0.40.30.2-0.4-0.4-0.4
Time in novel zone, NPP test0.10.10.2-0.30.3-0.3-0.3-0.40.30.2-0.3-0.4-0.4
Total zone transitions, NPP test0.10.10.2-0.10.4-0.4-0.3-0.30.30.4-0.3-0.3-0.4
Total locomotion distance, NPP test0.10.20.2-0.20.5-0.5-0.4-0.40.40.5-0.4-0.4-0.4
Locomotion velocity, NPP test0.10.20.2-0.20.4-0.5-0.4-0.40.40.4-0.4-0.4-0.4
Intraocular pressure0.10.20.5-0.60.4-0.6-0.4-0.40.60.7-0.4-0.3-0.3
Delta distance traveled before/after self-admin1.51.72.3-1.31.3-1.1-1.3-1.31.31.0-1.3-1.3-1.5
Delta ambulatory time before/after self-admin1.52.63.5-1.61.6-1.5-1.6-1.61.51.4-1.7-1.7-1.9
Parametrial fat weight2.35.46.32.3-2.42.42.32.3-2.5-2.52.32.32.1
Pavlov. Cond. lever latency0.30.40.5-0.70.5-0.6-0.6-0.60.60.5-0.6-0.6-0.6
Pavlov. Cond. magazine entry latency0.10.10.30.5-0.30.40.40.4-0.3-0.30.40.40.4
Pavlov. Cond. change in total contacts0.00.00.10.20.10.10.10.1-0.10.10.00.00.0
Pavlov. Cond. index score0.20.30.50.7-0.40.50.50.5-0.5-0.40.50.50.5
Pavlov. Cond. latency score0.30.40.50.7-0.50.60.60.6-0.6-0.50.60.60.6
Pavlov. Cond. lever contacts0.30.30.50.7-0.40.60.60.6-0.6-0.50.50.50.5
Pavlov. Cond. magazine entry number0.00.00.00.0-0.0-0.1-0.1-0.10.20.0-0.1-0.1-0.2
Pavlov. Cond. intertrial magazine entries1.51.82.0-1.21.2-1.4-1.3-1.41.41.3-1.3-1.3-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.5-0.20.30.40.3-0.3-0.20.30.30.3
Pavlov. Cond. response bias0.00.10.10.3-0.10.20.20.3-0.2-0.10.20.20.2
Pavlov. Cond. lever latency0.71.01.6-0.31.0-1.0-0.9-1.01.11.0-1.1-1.1-1.3
Pavlov. Cond. magazine entry latency0.60.91.20.6-0.81.00.91.0-1.0-0.91.01.01.1
Pavlov. Cond. change in total contacts0.00.00.1-0.2-0.10.10.10.1-0.1-0.10.20.20.3
Pavlov. Cond. index score0.60.91.30.5-0.90.90.90.9-1.0-0.91.01.01.1
Pavlov. Cond. latency score0.71.11.50.7-1.01.01.01.0-1.1-1.11.11.11.2
Pavlov. Cond. lever contacts0.71.01.50.3-1.01.00.91.0-1.1-1.01.11.11.2
Pavlov. Cond. magazine entry number0.10.10.2-0.00.2-0.3-0.3-0.30.40.3-0.3-0.3-0.5
Pavlov. Cond. intertrial magazine entries1.94.14.5-1.81.9-2.1-2.1-2.12.12.0-2.1-2.0-2.1
Pavlov. Cond. lever-magazine prob. diff.0.50.81.20.6-0.90.90.90.9-0.9-0.91.01.01.1
Pavlov. Cond. response bias1.11.52.20.6-1.21.21.21.2-1.3-1.21.31.31.5
Time in closed arm before self-admin0.50.81.40.8-0.31.11.01.0-0.6-1.21.00.90.9
Time in closed arm after self-admin0.50.61.60.1-1.30.80.60.7-0.7-0.70.70.70.8
Time in open arm before self-admin0.40.51.3-0.30.2-1.0-0.7-0.70.61.1-0.7-0.7-0.7
Time in open arm after self-admin0.80.92.0-0.11.4-1.0-0.8-0.91.01.0-1.0-0.9-1.0
Bone: periosteal estimation0.92.12.41.6-1.41.41.51.4-1.3-1.41.41.41.4
Bone: periosteal perimeter0.71.42.01.4-1.11.21.21.2-1.0-1.21.21.21.2
Bone: post-yield work0.71.21.4-0.81.1-1.1-1.1-1.11.21.1-1.1-1.1-1.1
Progressive ratio test 1 active lever presses0.10.31.10.41.1-0.6-0.2-0.30.60.6-0.3-0.2-0.2
Progressive ratio test 1 breakpoint0.20.41.50.21.2-0.7-0.4-0.40.70.7-0.4-0.4-0.3
Progressive ratio test 1 inactive lever presses0.20.51.21.10.20.50.70.7-0.6-0.50.70.70.6
Progressive ratio test 2 active lever presses0.30.41.10.21.1-0.8-0.5-0.50.90.8-0.5-0.5-0.4
Progressive ratio test 2 breakpoint0.50.71.50.01.2-0.9-0.6-0.71.00.9-0.7-0.7-0.6
Progressive ratio test 2 inactive lever presses0.10.20.90.01.0-0.4-0.2-0.20.50.4-0.3-0.2-0.2
Incentive Sensitization - Responses0.51.21.9-0.81.4-1.2-1.1-1.11.31.2-1.1-1.1-1.0
Incentive Sensitization - Breakpoint0.51.01.5-0.71.2-1.1-1.0-1.01.21.1-1.0-1.0-0.9
Sum of active levers in priming session hrs 5-60.10.10.1-0.3-0.1-0.3-0.3-0.30.20.2-0.3-0.3-0.4
Progressive ratio0.20.61.3-0.51.1-0.6-0.6-0.70.70.7-0.7-0.8-0.9
Food seeking constrained by brief footshock0.10.10.3-0.4-0.0-0.4-0.4-0.40.20.5-0.3-0.3-0.3
Seeking ratio, punishment vs. effort0.30.72.00.4-1.40.70.70.7-0.9-0.70.80.80.9
Retroperitoneal fat weight1.14.95.71.7-2.22.42.22.2-2.3-2.42.22.22.2
Reaction time number correct0.30.92.0-1.40.8-0.8-1.0-1.00.90.8-0.9-1.0-0.9
Reaction time mean minus median0.00.20.70.8-0.40.30.50.4-0.2-0.30.40.40.5
Reaction time mean minus median AUC0.00.00.10.20.3-0.2-0.1-0.10.40.2-0.1-0.1-0.1
Reaction time num false alarms0.20.40.9-0.30.7-0.7-0.6-0.60.90.7-0.6-0.6-0.5
Reaction time num false alarms AUC0.40.91.7-0.41.2-1.0-0.9-0.91.31.0-0.9-0.9-0.9
Reaction time trials correct on left0.30.92.0-1.40.8-0.8-1.0-1.00.90.8-0.9-1.0-0.9
Reaction time trials on left0.30.91.9-1.40.8-0.8-1.0-0.90.80.8-0.9-0.9-0.9
Reaction time mean0.91.92.31.5-1.41.31.41.4-1.2-1.31.41.41.4
Reaction time mean AUC0.61.62.71.6-1.21.11.31.3-1.0-1.11.21.31.2
Median of all reaction times1.62.52.71.6-1.61.51.61.6-1.5-1.51.61.61.6
Reaction time omissions0.50.91.11.0-0.80.91.01.0-0.8-0.90.91.01.1
Reaction time false alarm rate0.10.10.30.50.4-0.2-0.0-0.10.50.2-0.1-0.1-0.1
Reaction time premature initiation rate0.71.11.5-0.70.8-1.1-1.0-1.11.21.1-1.1-1.0-1.2
Reaction time premature initiations0.82.42.9-1.41.3-1.5-1.6-1.61.61.5-1.6-1.6-1.7
Std. dev. reaction times0.00.00.20.4-0.10.00.20.20.0-0.00.20.20.2
Reaction time trials completed0.30.91.9-1.40.8-0.8-1.0-0.90.80.8-0.9-0.9-0.9
Reaction time trials AUC0.31.22.4-1.60.9-0.9-1.1-1.11.00.9-1.0-1.1-1.0
Run reversals in cocaine runway, females0.20.20.30.4-0.20.50.50.5-0.6-0.50.60.50.5
Run reversals in cocaine runway, males0.00.00.1-0.10.4-0.2-0.1-0.20.10.1-0.1-0.1-0.1
Latency to leave start box in cocaine runway0.81.22.21.5-1.21.11.11.0-0.9-0.90.90.90.9
Latency to leave start box in cocaine runway, F2.02.52.71.6-1.51.61.61.6-1.6-1.51.61.61.6
Latency to leave start box in cocaine runway, M0.10.10.60.7-0.50.10.10.00.10.1-0.2-0.1-0.2
Std. dev. time between licks in bursts1.22.32.51.3-1.61.61.51.5-1.6-1.51.51.51.6
Total sessions with >9 infusions0.10.21.21.10.20.00.40.30.1-0.00.30.30.3
Short access day 1 total inactive lever presses2.14.25.5-1.22.2-2.2-2.0-2.02.12.4-2.1-2.0-2.0
Short access day 10 total inactive lever presses0.00.30.70.4-0.50.60.50.5-0.9-0.50.40.40.4
Short access day 1 total infusions0.10.21.01.00.20.10.50.40.0-0.00.40.50.5
Short access day 10 total infusions0.10.10.60.70.4-0.10.20.20.20.00.10.20.1
Short access total infusions0.50.72.21.5-0.10.50.90.9-0.5-0.60.90.91.0
Short access day 1 locomotion0.30.61.1-0.21.0-0.9-0.6-0.70.90.9-0.7-0.6-0.6
Short access day 10 total locomotion0.00.00.1-0.00.3-0.2-0.1-0.1-0.10.2-0.1-0.1-0.2
Short access total locomotion0.10.20.70.50.9-0.5-0.1-0.20.50.5-0.2-0.2-0.2
One hour access (0.3 mA shock)0.20.20.60.10.7-0.5-0.3-0.30.80.5-0.3-0.2-0.1
Compulsive drug intake0.30.40.60.1-0.70.70.60.7-0.5-0.70.70.70.8
One hour access (shock baseline)0.41.02.0-0.21.4-1.1-0.9-0.91.21.1-1.0-0.9-0.8
Social response proportion0.00.00.00.10.10.10.10.10.2-0.20.10.1-0.1
Social responses0.91.22.4-1.61.1-1.1-1.1-1.11.10.9-0.9-1.0-1.0
Social time2.23.44.0-1.52.0-1.8-1.8-1.82.01.7-1.8-1.8-2.0
Soleus weight0.51.61.91.4-1.21.31.31.2-1.1-1.31.21.21.2
Bone: stiffness0.00.10.40.6-0.10.10.20.20.1-0.10.10.10.1
Tibialis anterior weight0.72.52.7-1.61.5-1.6-1.6-1.61.61.5-1.6-1.6-1.6
Time to tail flick, vehicle, before self-admin0.70.91.60.6-0.60.91.01.0-0.9-1.01.01.01.3
Time to tail flick, vehicle, after self-admin0.50.91.30.5-0.71.11.01.0-0.9-1.11.01.01.1
Time to tail flick, test, before self-admin0.20.20.7-0.20.8-0.3-0.3-0.30.60.3-0.3-0.3-0.5
Time to tail flick, test, after self-admin0.30.30.7-0.50.8-0.4-0.4-0.40.80.4-0.4-0.4-0.5
Delta time to tail flick, vehicle, before/after SA0.40.40.5-0.60.6-0.6-0.6-0.60.70.6-0.6-0.7-0.7
Delta time to tail flick, test, before/after SA0.00.00.10.2-0.30.20.20.2-0.1-0.30.20.20.3
Tibia length0.51.32.11.4-1.21.11.21.1-1.0-1.11.11.11.0
Ambulatory time before self-admin0.51.61.81.1-1.31.31.31.3-1.2-1.31.31.31.3
Ambulatory time after self-admin0.00.00.1-0.0-0.20.10.00.00.1-0.30.00.0-0.2
Bone: tissue strength0.30.30.40.5-0.50.60.60.6-0.5-0.60.60.60.6
Total heroin consumption1.31.52.1-1.41.3-1.2-1.2-1.21.01.1-1.1-1.2-1.3
Bone: trabecular number0.10.31.5-1.20.5-0.3-0.4-0.30.20.5-0.3-0.3-0.1
Bone: trabecular spacing0.00.00.00.10.1-0.1-0.0-0.10.10.1-0.1-0.1-0.1
Bone: trabecular thickness0.00.00.00.2-0.1-0.1-0.0-0.00.2-0.1-0.0-0.0-0.0
Bone: trabecular tissue density0.00.00.0-0.10.1-0.0-0.1-0.10.00.1-0.1-0.1-0.1
Water consumed over 24 hours1.83.54.62.1-1.81.81.91.9-1.8-1.81.81.81.8
Number of responses in last shaping day0.20.31.30.11.1-0.5-0.3-0.30.90.4-0.3-0.3-0.3