Hub : Genes

Cdc42ep5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_008758944.4 0.02 0.01 3.0e-03 0.01 0.01 0.01 0.01 1.9e-03 2.7e-03 6.1e-03 3.5e-03
2 OFC gene expression Cdc42ep5 0.3 0.17 1.8e-04 0.07 0.09 0.1 0.1 9.1e-03 4.5e-03 2.0e-03 2.3e-03
3 Adipose alternative TSS XM_006228217.4 0.02 0.02 9.5e-03 0 0.01 0.01 0 1.6e-01 4.6e-02 5.8e-02 1.4e-01
4 Adipose alternative TSS XM_008758944.4 0.03 0.02 3.5e-03 0.01 0.02 0.01 0.01 6.2e-02 6.2e-03 1.9e-02 2.0e-02
5 Adipose alternative TSS XM_008758944.4 0.02 0.02 6.2e-03 0 0.01 0.01 0 9.3e-02 1.5e-02 4.0e-02 8.0e-02
6 Brain gene expression Cdc42ep5 0.05 0.04 1.4e-05 0.03 0.05 0.03 0.03 8.4e-04 2.3e-05 5.8e-04 6.8e-04
7 IL gene expression Cdc42ep5 0.29 0.16 3.1e-05 0.16 0.15 0.12 0.15 9.7e-05 1.8e-04 9.9e-04 1.6e-04
8 PL mRNA stability Cdc42ep5 0.04 0.03 2.0e-04 0.04 0.03 0.03 0.03 9.8e-05 5.7e-04 7.7e-04 4.1e-04
9 NAcc alternative TSS NM_001108469.1 0.05 0.03 2.9e-08 0.05 0.04 0.05 0.05 1.5e-08 5.3e-07 8.0e-08 6.5e-08
10 NAcc alternative TSS XM_006228217.4 0.01 0.01 4.5e-03 0.01 0.01 0.01 0.01 4.9e-03 2.8e-02 1.3e-02 3.0e-02
11 PL isoform ratio XM_006228217.4 0.04 0.03 1.9e-04 0.04 0.03 0.03 0.03 6.3e-05 1.3e-04 1.3e-04 1.2e-04
12 IC gene expression Cdc42ep5 0.33 0.16 9.7e-12 0.18 0.2 0.19 0.2 3.2e-08 8.5e-09 1.9e-08 5.1e-09
13 IC isoform ratio NM_001108469.1 0.08 0.06 4.3e-03 0.04 0.04 0.01 0.04 7.0e-03 1.3e-02 1.2e-01 1.1e-02
14 pVTA gene expression Cdc42ep5 0.13 0.08 1.4e-07 0.06 0.05 0.05 0.06 3.1e-05 3.5e-05 1.1e-04 1.4e-05
15 BLA gene expression Cdc42ep5 0.09 0.06 3.9e-04 0.06 0.05 0.05 0.05 5.0e-04 1.4e-03 1.5e-03 1.2e-03
16 PL gene expression Cdc42ep5 0.19 0.11 0.0e+00 0.19 0.2 0.2 0.2 1.4e-20 7.1e-21 3.7e-21 4.0e-21
17 IL mRNA stability Cdc42ep5 0.13 0.1 6.6e-03 0.1 0.05 0.09 0.07 2.0e-03 2.3e-02 4.0e-03 7.9e-03
18 NAcc mRNA stability Cdc42ep5 0.04 0.03 6.3e-07 0.04 0.04 0.04 0.04 2.0e-07 5.1e-07 3.8e-07 2.0e-07
19 NAcc alternative TSS XM_008758944.4 0.02 0.01 9.1e-04 0.02 0.02 0.02 0.02 4.4e-04 7.1e-04 7.3e-04 7.8e-04
20 PL alternative TSS NM_001108469.1 0.04 0.03 1.3e-04 0.03 0.04 0.03 0.03 1.1e-04 7.9e-05 1.6e-04 1.3e-04
21 PL alternative TSS XM_006228217.4 0.04 0.03 2.9e-04 0.03 0.04 0.03 0.03 3.7e-04 7.1e-05 6.1e-04 4.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.00.10.10.2-0.3-0.20.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.1-0.10.1-0.30.3
Area under the delay curve0.30.41.1-0.60.10.6-0.6-0.60.50.50.60.5-0.5-0.50.50.50.50.50.51.11.1-1.10.5-0.4
BMI with tail0.62.12.3-1.21.41.3-1.3-1.31.41.51.51.5-1.5-1.51.51.51.51.51.51.51.5-1.51.5-1.5
BMI without tail0.00.10.30.6-0.5-0.50.40.4-0.1-0.10.1-0.00.0-0.00.10.10.10.10.1-0.0-0.00.00.1-0.2
Body weight0.83.47.12.7-2.3-2.52.52.4-1.9-1.7-1.6-1.61.61.7-1.6-1.6-1.6-1.6-1.6-1.7-1.71.7-1.41.2
Weight adjusted by age0.91.31.60.8-1.0-0.91.01.0-1.2-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.2-1.2-1.1-1.11.1-1.31.3
Bone surface2.64.76.52.5-2.6-2.42.42.4-2.2-2.1-2.1-2.12.12.1-2.1-2.1-2.1-2.1-2.1-2.0-2.02.0-1.91.8
Bone volume2.03.55.12.2-2.3-2.22.22.1-1.9-1.8-1.8-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.7-1.71.7-1.71.6
Breakpoint value in progressive ratio session0.30.40.5-0.70.70.7-0.7-0.70.70.60.60.6-0.6-0.60.60.60.60.60.60.30.3-0.30.6-0.6
Number of licking bursts0.00.10.2-0.30.40.3-0.3-0.30.20.20.20.2-0.2-0.20.20.20.20.20.20.00.0-0.00.2-0.2
Context. condit. distance diff. score0.10.10.4-0.30.30.3-0.3-0.20.1-0.10.1-0.10.1-0.1-0.1-0.10.10.10.1-0.6-0.60.6-0.10.1
Locomotion velocity, session 10.80.92.3-0.40.20.2-0.20.0-0.7-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.1-1.11.1-1.31.5
Locomotion distance, session 13.74.76.91.4-1.5-1.51.61.7-2.1-2.2-2.2-2.22.22.2-2.2-2.2-2.2-2.2-2.2-2.6-2.62.6-2.32.4
Locomotion velocity, session 20.10.10.4-0.60.40.4-0.4-0.3-0.1-0.2-0.4-0.30.30.4-0.3-0.3-0.4-0.4-0.4-0.3-0.30.3-0.50.6
Locomotion distance, session 22.23.13.91.5-1.7-1.51.61.6-1.8-2.0-1.8-1.91.91.8-2.0-2.0-1.8-1.8-1.8-1.5-1.51.5-1.91.9
Locomotion velocity, session 30.10.10.3-0.30.20.3-0.3-0.20.1-0.00.0-0.00.0-0.0-0.0-0.00.00.00.0-0.5-0.50.5-0.10.1
Locomotion distance, session 30.50.51.20.2-0.3-0.30.30.4-0.6-0.7-0.8-0.70.70.8-0.7-0.7-0.8-0.8-0.8-1.1-1.11.1-0.80.9
Stereotopy head waving bouts, day 30.20.20.7-0.30.80.3-0.3-0.30.40.50.40.5-0.5-0.40.50.50.40.40.4-0.2-0.20.20.5-0.5
Stereotopy head waving duration, day 30.20.20.6-0.30.80.3-0.3-0.30.40.50.50.5-0.5-0.50.50.50.50.50.5-0.2-0.20.20.5-0.6
Locomotion velocity, session 70.30.31.30.1-0.0-0.10.20.2-0.4-0.5-0.4-0.60.60.4-0.6-0.6-0.4-0.4-0.4-1.1-1.11.1-0.60.6
Locomotion distance, session 70.20.20.50.0-0.2-0.00.10.1-0.4-0.6-0.3-0.60.60.4-0.6-0.6-0.4-0.4-0.4-0.4-0.40.4-0.60.7
Stereotopy head waving bouts, day 70.10.10.50.40.1-0.40.40.4-0.2-0.1-0.2-0.00.00.2-0.0-0.0-0.2-0.2-0.2-0.7-0.70.7-0.0-0.0
Stereotopy head waving duration, day 70.10.10.40.4-0.0-0.40.40.4-0.2-0.0-0.2-0.00.00.3-0.0-0.0-0.2-0.2-0.2-0.6-0.60.6-0.1-0.0
Locomotion velocity, session 80.30.41.3-0.20.10.2-0.1-0.0-0.3-0.6-0.4-0.60.60.3-0.6-0.6-0.4-0.4-0.4-1.1-1.11.1-0.60.7
Locomotion distance, session 80.50.71.30.4-0.5-0.40.40.5-0.7-1.0-0.7-1.01.00.7-1.0-1.0-0.7-0.7-0.7-1.1-1.11.1-1.01.0
Degree of sensitization distance0.00.00.00.1-0.1-0.10.10.1-0.1-0.20.0-0.20.2-0.0-0.2-0.2-0.0-0.0-0.0-0.1-0.10.1-0.10.1
Degree of sensitization stereotypy0.00.00.10.10.2-0.10.10.10.00.20.00.2-0.2-0.00.20.20.10.10.1-0.3-0.30.30.2-0.2
Conditioned locomotion0.20.20.80.0-0.3-0.10.10.2-0.4-0.4-0.5-0.50.50.4-0.4-0.4-0.4-0.4-0.4-0.9-0.90.9-0.50.6
Cocaine response after cond. corrected2.83.45.5-1.21.11.3-1.3-1.41.71.91.91.9-1.9-1.91.91.91.91.91.92.32.3-2.32.0-2.0
Cocaine response after cond. not corrected0.10.20.60.4-0.3-0.30.30.20.10.30.30.3-0.3-0.30.30.30.30.30.30.80.8-0.80.4-0.5
Cocaine response before conditioning7.89.39.83.0-2.6-3.03.03.1-3.1-3.1-3.1-3.13.13.1-3.1-3.1-3.1-3.1-3.1-3.1-3.13.1-3.02.9
Saline control response0.70.93.8-0.00.1-0.10.10.2-0.6-0.8-0.7-0.80.80.7-0.8-0.8-0.8-0.8-0.8-1.9-1.91.9-1.01.1
Bone: connectivity density0.00.00.1-0.30.10.3-0.3-0.30.20.20.20.2-0.2-0.30.20.20.20.20.20.20.2-0.20.2-0.1
Bone: cortical apparent density0.10.20.5-0.2-0.50.1-0.10.0-0.3-0.4-0.4-0.40.40.3-0.4-0.4-0.4-0.4-0.40.70.7-0.7-0.50.6
Bone: cortical area1.01.52.41.4-1.2-1.31.31.3-1.2-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-1.5-1.51.5-1.00.9
Bone: cortical porosity0.60.71.0-0.80.70.8-0.8-0.80.90.91.00.9-0.9-1.00.90.90.90.90.90.10.1-0.10.9-0.9
Bone: cortical porosity0.30.30.6-0.30.30.4-0.4-0.40.60.70.80.7-0.7-0.80.70.70.70.70.7-0.1-0.10.10.8-0.8
Bone: cortical thickness0.10.20.7-0.80.80.7-0.7-0.70.50.40.40.4-0.4-0.40.40.40.40.40.4-0.1-0.10.10.3-0.2
Bone: cortical thickness0.20.20.40.2-0.3-0.30.30.3-0.5-0.5-0.6-0.50.50.5-0.5-0.5-0.5-0.5-0.50.30.3-0.3-0.60.6
Bone: cortical tissue density0.10.20.5-0.2-0.50.1-0.10.0-0.2-0.3-0.4-0.30.30.3-0.4-0.4-0.4-0.4-0.40.70.7-0.7-0.50.6
Condit. Reinf. active minus inactive responses0.20.20.3-0.50.60.5-0.5-0.50.50.50.50.5-0.5-0.50.50.50.50.50.5-0.2-0.20.20.5-0.5
Condit. Reinf. active-inactive response ratio1.71.92.2-1.41.41.4-1.4-1.41.41.51.41.5-1.5-1.41.51.51.41.41.41.01.0-1.01.4-1.3
Condit. Reinf. active responses0.20.21.00.3-0.2-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-1.0-1.01.0-0.30.2
Condit. Reinf. inactive responses3.64.45.92.0-1.7-2.02.02.1-2.1-2.1-2.0-2.12.12.0-2.1-2.1-2.0-2.0-2.0-2.4-2.42.4-2.02.0
Incentive salience index mean0.10.10.20.2-0.3-0.20.20.2-0.2-0.3-0.2-0.30.30.2-0.3-0.3-0.2-0.2-0.2-0.5-0.50.5-0.20.2
Condit. Reinf. lever presses0.71.01.61.0-1.3-1.01.01.1-1.1-1.1-1.1-1.11.11.0-1.1-1.1-1.0-1.0-1.0-0.3-0.30.3-1.01.0
Condit. Reinf. active minus inactive responses4.25.56.42.4-2.5-2.42.42.4-2.4-2.4-2.4-2.42.42.3-2.3-2.3-2.3-2.3-2.3-2.2-2.22.2-2.22.1
Condit. Reinf. active-inactive response ratio4.45.18.62.8-2.9-2.72.72.6-2.4-2.2-2.2-2.32.32.2-2.2-2.2-2.2-2.2-2.2-1.6-1.61.6-2.01.9
Condit. Reinf. active responses4.15.77.12.1-2.1-2.22.22.2-2.4-2.4-2.4-2.42.42.4-2.4-2.4-2.4-2.4-2.4-2.7-2.72.7-2.42.4
Condit. Reinf. inactive responses0.40.52.00.00.3-0.10.10.2-0.4-0.5-0.5-0.50.50.6-0.5-0.5-0.5-0.5-0.5-1.4-1.41.4-0.60.7
Condit. Reinf. lever presses0.30.41.11.0-0.7-0.90.90.8-0.5-0.3-0.4-0.40.40.3-0.3-0.3-0.3-0.3-0.3-1.0-1.01.0-0.20.0
Condit. Reinf. lever reinforcers received4.96.98.52.4-2.3-2.42.42.5-2.6-2.6-2.6-2.72.72.6-2.6-2.6-2.6-2.6-2.6-2.9-2.92.9-2.62.6
Conditioned reinforcement - actives0.10.10.80.8-0.9-0.60.60.6-0.3-0.2-0.1-0.10.10.2-0.2-0.2-0.2-0.2-0.20.20.2-0.2-0.1-0.0
Conditioned reinforcement - inactives2.02.94.01.8-2.0-1.91.91.9-1.9-1.9-1.7-1.71.71.8-1.8-1.8-1.8-1.8-1.8-0.7-0.70.7-1.71.7
Conditioned locomotion0.10.10.50.5-0.7-0.40.40.3-0.2-0.1-0.0-0.00.00.0-0.1-0.1-0.1-0.1-0.10.60.6-0.60.0-0.1
Patch foraging indifference point 0 sec0.10.20.7-0.90.70.8-0.7-0.70.40.20.30.3-0.3-0.20.10.10.10.10.2-0.6-0.60.60.1-0.0
Patch foraging indifference point AUC0.81.11.3-1.11.21.1-1.1-1.11.11.01.11.1-1.1-1.01.11.11.11.11.10.90.9-0.91.0-1.0
Delay disc. indifference point, 0s delay0.20.20.6-0.3-0.00.1-0.00.1-0.4-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.4-0.40.4-0.70.8
Delay disc. indifference point, 16s delay1.61.82.8-0.60.50.8-0.8-0.91.21.41.51.4-1.4-1.41.41.41.41.41.41.71.7-1.71.4-1.5
Delay disc. indifference point, 2s delay0.30.41.5-0.80.20.7-0.7-0.60.40.30.40.3-0.3-0.30.30.30.30.30.31.21.2-1.20.3-0.2
Delay disc. indifference point, 24s delay1.21.32.7-0.70.30.8-0.9-0.91.11.21.21.1-1.1-1.21.11.11.11.11.11.61.6-1.61.1-1.1
Delay disc. indifference point, 4s delay0.10.10.60.4-0.7-0.40.40.3-0.3-0.2-0.1-0.20.20.2-0.2-0.2-0.2-0.2-0.20.10.1-0.1-0.20.2
Delay disc. indifference point, 8s delay0.10.10.3-0.30.10.3-0.3-0.30.20.10.20.1-0.1-0.10.10.10.10.10.10.60.6-0.60.1-0.1
Indifference point function ln k6.010.411.33.1-3.2-3.13.13.2-3.3-3.3-3.4-3.43.43.4-3.3-3.3-3.3-3.3-3.3-3.0-3.03.0-3.33.2
Indifference point function log k6.010.411.33.1-3.2-3.13.13.2-3.3-3.3-3.4-3.43.43.4-3.3-3.3-3.3-3.3-3.3-3.0-3.03.0-3.33.2
Patch foraging total patch changes 0 sec0.10.20.7-0.80.60.7-0.7-0.60.40.20.20.2-0.2-0.20.10.10.10.10.1-0.5-0.50.50.1-0.0
Patch foraging total patch changes 12 sec0.40.50.7-0.70.60.7-0.7-0.70.80.80.80.8-0.8-0.70.80.80.80.80.80.40.4-0.40.8-0.8
Patch foraging total patch changes 18 sec0.40.61.3-0.91.20.9-0.9-0.90.80.80.80.7-0.7-0.80.70.70.70.70.7-0.5-0.50.50.7-0.6
Patch foraging total patch changes 24 sec0.20.30.5-0.1-0.10.2-0.2-0.30.50.50.60.6-0.6-0.50.60.60.60.60.60.60.6-0.60.7-0.7
Patch foraging total patch changes 6 sec0.91.41.7-1.31.31.3-1.3-1.31.31.21.21.2-1.2-1.21.31.31.31.31.30.50.5-0.51.2-1.2
Patch foraging time to switch 0 sec3.67.510.7-1.51.91.8-1.8-2.02.73.13.03.0-3.0-3.03.03.03.03.03.02.62.6-2.63.1-3.3
Patch foraging water rate 0 sec0.81.82.60.7-1.0-0.80.91.0-1.3-1.5-1.5-1.51.51.5-1.5-1.5-1.5-1.5-1.5-1.3-1.31.3-1.51.6
Patch foraging water rate 12 sec2.96.28.11.7-1.9-1.81.92.0-2.5-2.7-2.7-2.72.72.6-2.7-2.7-2.7-2.7-2.7-2.5-2.52.5-2.82.9
Patch foraging water rate 18 sec1.62.43.50.9-1.2-1.11.11.2-1.6-1.8-1.7-1.81.81.7-1.6-1.6-1.6-1.6-1.6-1.5-1.51.5-1.81.9
Patch foraging water rate 24 sec1.52.22.90.9-1.1-1.01.11.2-1.4-1.6-1.5-1.61.61.5-1.6-1.6-1.6-1.6-1.6-1.7-1.71.7-1.61.6
Patch foraging water rate 6 sec6.18.89.93.1-3.1-3.13.13.1-3.1-3.0-3.0-3.03.03.0-2.9-2.9-2.9-2.9-2.9-2.9-2.92.9-2.82.7
Seeking ratio, delayed vs. immediate footshock0.60.71.3-0.10.0-0.20.20.3-0.7-0.9-1.0-0.90.90.9-0.9-0.9-0.9-0.9-0.9-1.1-1.11.1-1.01.1
Distance traveled before self-admin4.05.27.61.1-1.5-1.51.61.8-2.3-2.6-2.6-2.62.62.5-2.6-2.6-2.6-2.6-2.6-2.1-2.12.1-2.62.8
Distance traveled after self-admin0.20.20.6-0.80.50.5-0.5-0.3-0.1-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.6-0.60.6-0.60.7
Extensor digitorum longus weight0.10.51.41.2-1.1-1.11.01.0-0.7-0.6-0.4-0.50.50.6-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.30.2
Bone: elastic displacement0.40.51.9-1.01.40.9-0.9-0.80.60.50.60.5-0.5-0.50.50.50.50.50.5-0.7-0.70.70.4-0.3
Bone: elastic work0.70.91.80.7-0.2-0.70.70.8-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-1.4-1.41.4-0.90.9
Bone: endosteal estimation2.35.08.93.0-2.7-2.92.82.7-2.4-2.1-2.1-2.12.12.1-2.1-2.1-2.1-2.1-2.1-1.7-1.71.7-1.91.7
Bone: endosteal perimeter1.73.65.52.4-2.1-2.32.32.2-2.0-1.8-1.8-1.81.81.9-1.8-1.8-1.8-1.8-1.8-1.8-1.81.8-1.61.5
Epididymis fat weight0.20.61.50.30.1-0.0-0.0-0.20.60.91.00.9-0.9-0.90.70.70.90.90.90.80.8-0.81.1-1.2
Delta time in closed arm before/after self-admin0.10.10.5-0.30.30.3-0.3-0.30.20.20.20.2-0.2-0.20.20.20.20.20.20.70.7-0.70.2-0.2
Delta time in open arm before/after self-admin2.42.44.21.2-1.0-1.31.31.4-1.5-1.5-1.5-1.51.51.5-1.5-1.5-1.5-1.5-1.5-2.0-2.02.0-1.51.5
Diff in mean of infusions in LGA sessions0.40.50.80.0-0.1-0.20.30.3-0.6-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.80.9
Delay discount exponential model param0.20.30.90.40.0-0.40.40.4-0.4-0.4-0.5-0.40.40.4-0.4-0.4-0.4-0.4-0.4-1.0-1.01.0-0.40.4
Extinction: sum of active levers before priming0.00.00.3-0.50.40.4-0.4-0.40.20.10.10.1-0.1-0.10.10.10.10.10.10.10.1-0.10.00.0
Active lever presses in extinction session 60.80.81.40.10.00.2-0.2-0.40.71.01.01.0-1.0-1.01.01.01.01.01.01.21.2-1.21.1-1.2
Bone: final force1.93.04.42.1-1.9-2.12.02.0-1.9-1.8-1.8-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.0-1.01.0-1.61.5
Bone: final moment2.64.25.62.4-2.2-2.32.32.3-2.2-2.1-2.1-2.12.12.1-2.1-2.1-2.1-2.1-2.1-1.3-1.31.3-2.01.9
Food consumed during 24 hour testing period1.52.02.71.6-1.3-1.61.61.6-1.5-1.5-1.4-1.41.41.5-1.4-1.4-1.4-1.4-1.4-1.3-1.31.3-1.31.2
Glucose0.91.42.7-1.61.51.6-1.6-1.51.21.01.11.0-1.0-1.11.01.01.21.21.21.11.1-1.10.9-0.7
Heart weight0.91.42.91.7-1.6-1.61.61.5-1.2-1.1-1.0-1.11.11.0-1.0-1.0-0.9-0.9-0.9-1.1-1.11.1-0.90.8
Delay discount hyperbolic model param0.30.31.20.5-0.0-0.50.50.5-0.5-0.5-0.5-0.40.40.5-0.4-0.4-0.4-0.4-0.4-1.1-1.11.1-0.40.4
Intermittent access intake day 1-15 change0.40.71.21.1-1.1-1.01.01.0-0.9-0.9-0.9-0.90.90.8-0.9-0.9-0.9-0.9-0.9-0.4-0.40.4-0.80.7
Intermittent access intake escalation0.51.11.91.4-1.4-1.31.31.3-1.1-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-0.6-0.60.6-0.90.8
Intermittent access intake escalation 20.30.40.60.3-0.4-0.40.40.4-0.6-0.7-0.8-0.80.80.7-0.7-0.7-0.7-0.7-0.7-0.4-0.40.4-0.70.8
Intermitt. access day 1 inactive lever presses0.31.12.41.5-1.5-1.41.41.3-1.1-1.0-1.0-1.01.01.0-0.9-0.9-0.9-0.9-0.9-0.4-0.40.4-0.80.7
Intermitt. access day 15 inactive lever presses0.91.84.22.1-2.0-1.91.91.8-1.4-1.2-1.1-1.11.11.2-1.2-1.2-1.2-1.2-1.2-0.6-0.60.6-1.00.8
Intermitt. access escalation Index0.60.82.3-0.70.60.7-0.7-0.80.80.70.70.7-0.7-0.70.70.70.70.70.71.51.5-1.50.7-0.7
Intermittent access day 1 total infusions0.20.31.31.0-1.1-0.90.80.8-0.6-0.5-0.4-0.40.40.5-0.5-0.5-0.5-0.5-0.50.10.1-0.1-0.40.3
Intermittent access day 15 total infusions0.50.72.51.4-1.6-1.21.21.1-0.9-0.7-0.7-0.60.60.7-0.7-0.7-0.7-0.7-0.70.20.2-0.2-0.50.4
Intermittent access terminal intake (last 3 days)0.50.72.31.2-1.5-1.21.11.1-0.9-0.8-0.7-0.70.70.7-0.8-0.8-0.8-0.8-0.80.20.2-0.2-0.60.5
Intermittent access total infusions0.91.03.11.5-1.8-1.41.41.3-1.1-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.0-0.00.0-0.80.7
Intermittent access day 1 locomotion0.91.12.71.4-1.6-1.31.31.3-1.1-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.00.30.3-0.3-0.90.8
Intermittent access day 15 total locomotion1.42.53.11.5-1.6-1.51.61.6-1.7-1.8-1.7-1.71.71.7-1.7-1.7-1.7-1.7-1.7-0.8-0.80.8-1.71.7
Intermittent access total locomotion2.83.45.82.2-2.4-2.22.22.2-2.0-1.9-1.9-1.91.91.9-1.9-1.9-1.9-1.9-1.9-0.5-0.50.5-1.71.6
Intermittent access standard deviation0.10.20.5-0.50.20.5-0.5-0.50.40.30.30.3-0.3-0.30.30.30.30.30.30.70.7-0.70.3-0.2
Left kidney weight4.822.130.45.5-5.1-5.45.45.3-4.8-4.6-4.5-4.54.54.5-4.5-4.5-4.5-4.5-4.5-4.6-4.64.6-4.23.9
Right kidney weight4.319.831.15.6-5.0-5.45.35.2-4.6-4.3-4.1-4.24.24.2-4.2-4.2-4.1-4.1-4.1-4.3-4.34.3-3.83.4
Cocaine induced anxiety0.91.21.91.2-1.0-1.21.21.2-1.1-1.0-1.2-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.4-1.41.4-1.00.9
Post-drug Anxiety0.30.30.70.8-0.6-0.70.70.6-0.4-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.9-0.90.9-0.20.1
Baseline Anxiety0.80.91.5-0.90.91.0-1.0-1.01.01.01.21.0-1.0-1.01.01.01.01.01.00.90.9-0.90.9-0.9
Tail length3.011.515.63.9-3.9-3.83.83.8-3.5-3.4-3.2-3.33.33.3-3.2-3.2-3.2-3.2-3.2-3.3-3.33.3-3.02.8
Length with tail2.410.417.34.2-4.0-4.03.93.8-3.3-3.0-3.0-3.03.03.0-2.9-2.9-2.9-2.9-3.0-3.0-3.03.0-2.62.4
Length without tail0.72.46.62.6-2.3-2.42.32.2-1.5-1.1-1.3-1.21.21.2-1.1-1.1-1.2-1.2-1.2-1.3-1.31.3-0.90.6
Times rat made contact with spout0.10.10.2-0.20.40.2-0.2-0.30.40.40.40.4-0.4-0.40.40.40.40.40.40.20.2-0.20.4-0.5
Lifetime Intake0.50.72.21.3-1.5-1.21.11.1-0.9-0.7-0.7-0.60.60.7-0.7-0.7-0.7-0.7-0.70.10.1-0.1-0.60.5
Liver weight, left0.91.42.31.5-1.4-1.51.41.4-1.2-1.1-1.1-1.11.11.2-1.1-1.1-1.1-1.1-1.1-1.1-1.11.1-1.00.9
Liver weight, right0.00.00.10.2-0.2-0.20.20.2-0.1-0.1-0.2-0.10.10.1-0.1-0.1-0.0-0.0-0.0-0.1-0.10.1-0.00.0
Locomotor activity0.10.20.4-0.20.30.2-0.3-0.30.40.50.40.4-0.4-0.50.40.40.40.40.40.60.6-0.60.5-0.5
Locomotor testing distance0.10.10.40.4-0.2-0.20.20.10.10.30.30.3-0.3-0.30.30.30.30.30.30.60.6-0.60.4-0.5
Locomotor testing rearing0.20.31.01.0-1.0-0.90.90.8-0.6-0.4-0.5-0.50.50.4-0.4-0.4-0.4-0.4-0.4-0.2-0.20.2-0.30.2
Locomotion in novel chamber0.70.91.2-1.11.01.1-1.1-1.11.01.00.80.9-0.9-1.01.01.01.01.01.00.90.9-0.90.9-0.8
Locomotion in novel chamber post-restriction0.61.01.7-0.80.70.8-0.8-0.90.90.90.90.9-0.9-1.01.01.01.01.01.01.31.3-1.30.9-0.9
Fecal boli incidents, locomotor time 10.30.40.50.6-0.6-0.60.60.6-0.6-0.7-0.6-0.70.70.6-0.7-0.7-0.7-0.7-0.7-0.5-0.50.5-0.60.6
Change in fecal boli incidents, locomotor task2.62.63.6-1.91.71.9-1.8-1.81.61.51.51.5-1.5-1.51.51.51.51.51.51.81.8-1.81.4-1.3
Time >=10cm from walls, locomotor time 10.10.10.2-0.20.20.2-0.3-0.30.40.40.30.4-0.4-0.40.40.40.40.40.40.30.3-0.30.4-0.4
Bouts of movement, locomotor time 11.21.42.10.1-0.2-0.40.50.6-1.0-1.3-1.4-1.31.31.2-1.3-1.3-1.3-1.3-1.3-1.4-1.41.4-1.41.5
Total resting periods, locomotor time 10.30.30.6-0.20.20.1-0.00.1-0.4-0.6-0.7-0.60.60.5-0.6-0.6-0.6-0.6-0.6-0.7-0.70.7-0.70.8
Rest time, locomotor task time 10.81.01.71.3-1.3-1.11.11.1-1.0-1.0-0.9-1.01.00.7-1.0-1.0-1.0-1.0-1.0-0.7-0.70.7-0.80.8
Distance moved, locomotor task time 10.71.12.0-1.31.41.2-1.2-1.21.11.10.91.1-1.1-0.81.11.11.11.11.10.60.6-0.60.9-0.8
Vertical activity count, locomotor time 10.51.34.0-2.02.01.7-1.7-1.61.10.90.90.9-0.9-0.80.90.90.90.90.90.40.4-0.40.6-0.5
Time >=10cm from walls, locomotor time 20.91.31.5-1.01.01.1-1.1-1.11.21.21.01.2-1.2-1.21.21.21.21.21.21.21.2-1.21.2-1.1
Bouts of movement, locomotor time 20.00.00.00.1-0.1-0.10.10.1-0.1-0.0-0.2-0.00.00.1-0.0-0.0-0.0-0.0-0.00.10.1-0.1-0.10.1
Total resting periods, locomotor time 20.00.00.10.1-0.2-0.20.20.2-0.2-0.2-0.3-0.20.20.3-0.2-0.2-0.2-0.2-0.20.10.1-0.1-0.20.2
Rest time, locomotor task time 20.10.20.3-0.0-0.1-0.10.10.2-0.4-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.3-0.30.3-0.50.6
Distance moved, locomotor task time 20.10.10.3-0.50.50.4-0.4-0.40.40.40.30.4-0.4-0.30.40.40.40.40.40.10.1-0.10.3-0.3
Vertical activity count, locomotor time 20.00.00.2-0.40.40.3-0.3-0.30.20.10.10.1-0.10.00.10.10.10.10.10.00.0-0.00.00.0
Light reinforcement 10.20.41.0-0.50.20.3-0.3-0.1-0.3-0.6-0.6-0.60.60.6-0.5-0.5-0.5-0.5-0.5-1.0-1.01.0-0.80.9
Light reinforcement 20.81.32.8-1.71.51.6-1.5-1.51.21.11.01.0-1.0-1.11.01.01.01.01.00.70.7-0.70.8-0.7
Bone: marrow area2.35.08.93.0-2.7-2.92.82.7-2.3-2.1-2.1-2.12.12.1-2.1-2.1-2.1-2.1-2.1-1.7-1.71.7-1.81.6
Bone: maximum diameter0.91.63.01.7-1.3-1.61.61.5-1.2-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-1.5-1.51.5-0.90.7
Bone: maximum force2.54.57.22.7-2.2-2.62.62.5-2.2-2.1-2.1-2.12.12.1-2.1-2.1-2.1-2.1-2.1-1.7-1.71.7-1.91.7
Bone: maximum moment3.35.78.32.9-2.4-2.82.82.7-2.5-2.4-2.4-2.42.42.4-2.4-2.4-2.4-2.4-2.4-2.0-2.02.0-2.22.0
Mean time between licks in bursts0.20.40.9-1.00.70.9-0.9-0.80.60.40.40.5-0.5-0.40.50.50.50.50.50.70.7-0.70.3-0.2
Mean num. licks in bursts0.00.00.20.4-0.4-0.40.40.3-0.2-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.10.10.1-0.10.0-0.1
Cd content in liver2.22.42.91.6-1.7-1.61.61.6-1.6-1.6-1.6-1.61.61.6-1.6-1.6-1.7-1.7-1.7-1.1-1.11.1-1.61.5
Co content in liver1.51.72.80.7-1.4-0.90.91.0-1.3-1.4-1.5-1.51.51.5-1.5-1.5-1.5-1.5-1.5-0.8-0.80.8-1.61.7
Cu content in liver0.70.81.51.0-1.2-1.01.01.0-0.9-0.8-0.8-0.90.90.8-0.9-0.9-1.0-1.0-1.0-0.8-0.80.8-0.80.8
Fe content in liver0.30.30.70.6-0.8-0.60.60.6-0.6-0.5-0.5-0.50.50.5-0.5-0.5-0.6-0.6-0.6-0.5-0.50.5-0.50.5
K content in liver0.00.00.2-0.10.30.1-0.1-0.10.00.10.10.1-0.1-0.00.00.00.10.10.1-0.5-0.50.50.00.0
Mg content in liver0.30.30.5-0.30.30.3-0.3-0.40.50.70.70.6-0.6-0.70.60.60.60.60.60.20.2-0.20.7-0.7
Mn content in liver0.20.20.4-0.10.20.1-0.1-0.20.30.50.50.4-0.4-0.50.40.40.50.50.5-0.6-0.60.60.5-0.5
Na content in liver2.52.74.2-2.02.02.0-1.9-1.91.81.81.71.7-1.7-1.71.71.71.71.71.70.60.6-0.61.5-1.4
Rb content in liver1.92.23.81.8-1.5-1.81.71.7-1.4-1.3-1.3-1.31.31.3-1.3-1.3-1.3-1.3-1.3-2.0-2.02.0-1.11.0
Se content in liver2.63.13.8-1.51.71.6-1.6-1.71.81.91.91.9-1.9-1.91.91.91.91.91.91.11.1-1.11.9-1.9
Sr content in liver2.92.57.0-2.62.42.3-2.3-2.21.71.31.31.3-1.3-1.31.31.31.31.31.31.01.0-1.01.1-0.9
Zn content in liver1.31.53.0-0.60.50.7-0.8-0.81.11.31.31.2-1.2-1.31.21.21.21.21.21.71.7-1.71.3-1.3
Bone: minimum diameter3.36.07.92.8-2.5-2.72.72.7-2.5-2.4-2.3-2.32.32.4-2.3-2.3-2.3-2.3-2.3-2.6-2.62.6-2.12.0
Time in familiar zone, hab. session 14.64.45.41.8-2.2-1.91.92.0-2.2-2.3-2.2-2.32.32.2-2.3-2.3-2.3-2.3-2.3-1.3-1.31.3-2.32.3
Time in novel zone, hab. session 12.92.94.8-1.82.21.8-1.8-1.81.81.81.81.8-1.8-1.71.81.81.71.71.70.80.8-0.81.7-1.7
Total zone transitions, hab. session 11.62.23.90.5-0.9-0.70.80.9-1.4-1.6-1.7-1.61.61.7-1.6-1.6-1.7-1.7-1.7-1.5-1.51.5-1.82.0
Total locomotion distance, hab. session 10.70.92.00.2-0.5-0.30.40.5-0.9-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-0.9-0.90.9-1.31.4
Locomotion velocity, hab. session 10.50.61.40.1-0.5-0.30.30.4-0.8-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.6-0.60.6-1.11.2
Time in familiar zone, hab. session 21.81.94.22.0-2.0-1.91.91.8-1.4-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.2-1.2-0.7-0.70.7-1.00.8
Time in novel zone, hab. session 21.41.43.1-1.61.81.5-1.5-1.51.31.11.21.1-1.1-1.21.11.11.21.21.20.60.6-0.61.0-0.9
Total zone transitions, hab. session 23.14.05.51.5-1.5-1.61.61.7-1.9-2.0-2.1-2.02.02.1-2.0-2.0-2.1-2.1-2.1-2.3-2.32.3-2.12.1
Total locomotion distance, hab. session 20.30.30.7-0.0-0.1-0.10.10.2-0.5-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.7-0.70.7-0.80.8
Locomotion velocity, hab. session 20.20.30.7-0.20.00.1-0.10.0-0.4-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.7-0.70.7-0.70.8
Novel to familiar place preference ratio0.00.00.00.10.0-0.10.10.1-0.00.10.00.1-0.10.00.10.1-0.0-0.0-0.0-0.1-0.10.10.1-0.1
Novelty place preference0.10.10.20.4-0.2-0.40.40.4-0.3-0.2-0.3-0.20.20.3-0.2-0.2-0.3-0.3-0.3-0.4-0.40.4-0.20.2
Time in novel zone, NPP test0.10.10.20.5-0.3-0.40.40.4-0.3-0.2-0.3-0.20.20.3-0.2-0.2-0.3-0.3-0.3-0.3-0.30.3-0.20.2
Total zone transitions, NPP test0.50.81.10.5-0.6-0.50.60.6-0.9-0.9-1.0-0.90.90.9-0.9-0.9-1.0-1.0-1.0-1.0-1.01.0-1.01.1
Total locomotion distance, NPP test0.40.51.00.7-0.5-0.60.60.7-0.7-0.7-0.7-0.70.70.6-0.7-0.7-0.6-0.6-0.6-1.0-1.01.0-0.70.6
Locomotion velocity, NPP test0.50.71.60.6-0.5-0.60.70.7-0.8-0.8-0.8-0.90.90.8-0.9-0.9-0.8-0.8-0.8-1.2-1.21.2-0.90.9
Intraocular pressure0.00.00.1-0.30.20.2-0.2-0.20.10.00.00.0-0.0-0.0-0.0-0.0-0.0-0.0-0.0-0.2-0.20.2-0.10.1
Delta distance traveled before/after self-admin2.12.32.6-1.61.61.6-1.6-1.61.61.61.61.6-1.6-1.61.61.61.61.61.60.90.9-0.91.5-1.5
Delta ambulatory time before/after self-admin1.31.62.1-1.41.41.4-1.4-1.41.41.31.31.3-1.3-1.31.31.31.31.31.30.70.7-0.71.2-1.2
Parametrial fat weight1.94.44.9-1.92.22.0-2.1-2.12.12.12.12.2-2.2-2.12.12.12.22.22.12.12.1-2.12.0-2.0
Pavlov. Cond. lever latency0.00.10.2-0.40.40.4-0.4-0.30.20.10.30.1-0.1-0.20.10.10.20.20.2-0.2-0.20.20.1-0.1
Pavlov. Cond. magazine entry latency1.11.42.5-0.90.90.9-0.9-1.01.11.21.21.2-1.2-1.11.21.21.21.21.21.61.6-1.61.2-1.2
Pavlov. Cond. change in total contacts0.30.30.5-0.60.50.6-0.6-0.50.50.60.40.6-0.6-0.30.60.60.40.40.40.70.7-0.70.4-0.4
Pavlov. Cond. index score0.40.51.5-0.60.50.6-0.6-0.60.60.70.60.7-0.7-0.60.70.70.60.60.61.21.2-1.20.6-0.6
Pavlov. Cond. latency score0.40.51.5-0.50.40.5-0.5-0.50.50.60.50.6-0.6-0.50.60.60.50.50.51.21.2-1.20.6-0.6
Pavlov. Cond. lever contacts0.00.00.20.4-0.3-0.40.40.3-0.10.1-0.10.1-0.10.10.10.1-0.1-0.1-0.10.30.3-0.30.1-0.2
Pavlov. Cond. magazine entry number0.40.51.20.5-0.4-0.50.50.6-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-1.1-1.11.1-0.70.7
Pavlov. Cond. intertrial magazine entries0.50.72.5-0.40.50.2-0.2-0.1-0.4-0.6-0.7-0.60.60.6-0.6-0.6-0.7-0.7-0.7-1.6-1.61.6-0.81.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.60.50.6-0.6-0.60.70.70.60.7-0.7-0.60.70.70.60.60.61.11.1-1.10.7-0.7
Pavlov. Cond. response bias0.20.30.7-0.00.10.1-0.1-0.20.40.50.40.5-0.5-0.40.50.50.40.40.40.80.8-0.80.6-0.6
Pavlov. Cond. lever latency0.30.40.80.7-0.9-0.70.70.7-0.7-0.7-0.6-0.60.60.6-0.7-0.7-0.7-0.7-0.70.10.1-0.1-0.60.6
Pavlov. Cond. magazine entry latency1.21.41.9-1.01.31.1-1.1-1.11.31.31.31.3-1.3-1.31.31.31.31.31.30.60.6-0.61.3-1.4
Pavlov. Cond. change in total contacts0.30.41.80.4-0.1-0.40.40.4-0.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.5-0.5-1.4-1.41.4-0.50.5
Pavlov. Cond. index score0.20.20.3-0.20.60.3-0.3-0.30.50.50.50.5-0.5-0.50.50.50.50.50.5-0.3-0.30.30.6-0.6
Pavlov. Cond. latency score0.50.71.0-0.71.00.7-0.7-0.80.90.90.90.9-0.9-0.90.90.90.90.90.90.10.1-0.11.0-1.0
Pavlov. Cond. lever contacts0.10.10.3-0.30.60.3-0.3-0.30.40.40.40.4-0.4-0.40.40.40.40.40.4-0.4-0.40.40.4-0.4
Pavlov. Cond. magazine entry number0.60.70.90.7-0.8-0.80.80.8-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.6-0.60.6-1.01.0
Pavlov. Cond. intertrial magazine entries3.14.65.52.2-2.3-2.22.22.2-2.2-2.2-2.2-2.22.22.2-2.2-2.2-2.2-2.2-2.2-1.7-1.71.7-2.22.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.4-0.40.60.4-0.4-0.50.50.60.50.5-0.5-0.50.60.60.60.60.6-0.1-0.10.10.6-0.6
Pavlov. Cond. response bias0.10.10.70.3-0.0-0.30.30.3-0.2-0.1-0.2-0.20.20.2-0.1-0.1-0.1-0.1-0.1-0.8-0.80.8-0.10.1
Time in closed arm before self-admin0.91.11.91.0-1.0-1.11.11.1-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.4-1.41.4-0.90.9
Time in closed arm after self-admin0.00.00.10.3-0.2-0.30.30.2-0.10.00.00.0-0.0-0.00.00.00.00.00.0-0.3-0.30.30.1-0.1
Time in open arm before self-admin2.32.52.7-1.61.61.6-1.6-1.71.61.61.61.6-1.6-1.61.61.61.61.61.61.61.6-1.61.5-1.4
Time in open arm after self-admin0.10.10.4-0.50.60.4-0.4-0.40.20.10.10.1-0.1-0.10.10.10.10.10.10.00.0-0.00.10.0
Bone: periosteal estimation2.14.36.72.6-2.3-2.52.52.4-2.1-2.0-1.9-2.02.02.0-2.0-2.0-2.0-2.0-2.0-2.0-2.02.0-1.71.6
Bone: periosteal perimeter1.93.34.32.1-1.8-2.02.02.0-1.8-1.7-1.7-1.71.71.8-1.7-1.7-1.7-1.7-1.7-1.9-1.91.9-1.61.5
Bone: post-yield work2.23.26.32.5-2.4-2.42.42.3-1.8-1.6-1.6-1.61.61.6-1.6-1.6-1.6-1.6-1.6-1.5-1.51.5-1.31.1
Progressive ratio test 1 active lever presses1.01.21.40.9-0.9-0.91.01.0-1.1-1.2-1.1-1.11.11.2-1.2-1.2-1.2-1.2-1.2-1.1-1.11.1-1.21.2
Progressive ratio test 1 breakpoint1.01.21.40.9-0.9-0.91.01.0-1.1-1.2-1.1-1.11.11.2-1.2-1.2-1.2-1.2-1.2-1.0-1.01.0-1.21.2
Progressive ratio test 1 inactive lever presses2.23.24.12.0-2.0-2.02.02.0-1.9-1.9-1.8-1.81.81.9-1.9-1.9-1.9-1.9-1.9-1.1-1.11.1-1.81.7
Progressive ratio test 2 active lever presses0.20.31.01.0-1.0-0.90.80.8-0.5-0.4-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.2-0.20.2-0.20.1
Progressive ratio test 2 breakpoint0.30.31.21.1-1.0-1.00.90.9-0.6-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.30.3-0.20.1
Progressive ratio test 2 inactive lever presses2.43.95.72.3-2.4-2.32.32.3-2.1-2.0-1.9-1.91.92.0-2.0-2.0-2.0-2.0-2.0-1.4-1.41.4-1.81.7
Incentive Sensitization - Responses0.60.92.91.7-1.5-1.51.41.3-0.9-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.7-0.50.3
Incentive Sensitization - Breakpoint0.40.52.01.4-1.3-1.21.21.1-0.7-0.4-0.5-0.50.50.4-0.4-0.4-0.4-0.4-0.4-0.5-0.50.5-0.20.1
Sum of active levers in priming session hrs 5-60.00.00.1-0.30.10.2-0.2-0.1-0.1-0.2-0.2-0.20.20.1-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.20.3
Progressive ratio0.10.20.7-0.20.40.1-0.1-0.0-0.2-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.8-0.80.8-0.40.4
Food seeking constrained by brief footshock2.73.36.6-0.50.5-0.10.20.5-1.4-2.0-2.0-2.02.02.0-2.0-2.0-2.0-2.0-2.0-2.2-2.22.2-2.32.6
Seeking ratio, punishment vs. effort0.91.21.70.7-0.8-0.80.90.9-1.1-1.3-1.3-1.21.21.3-1.2-1.2-1.2-1.2-1.2-0.8-0.80.8-1.31.3
Retroperitoneal fat weight5.021.525.0-3.94.04.2-4.2-4.34.74.74.94.8-4.8-4.84.84.85.05.04.94.74.7-4.74.7-4.7
Reaction time number correct0.10.20.5-0.50.40.5-0.5-0.50.30.30.20.2-0.2-0.30.20.20.20.20.20.70.7-0.70.2-0.2
Reaction time mean minus median0.10.11.00.2-0.4-0.10.10.1-0.0-0.00.00.0-0.00.00.00.00.00.00.01.01.0-1.00.1-0.1
Reaction time mean minus median AUC0.10.20.80.1-0.2-0.00.0-0.00.20.20.20.3-0.3-0.20.20.20.20.20.20.90.9-0.90.3-0.3
Reaction time num false alarms0.00.00.10.1-0.3-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.3-0.3-0.3-0.3-0.30.00.0-0.0-0.20.2
Reaction time num false alarms AUC0.00.00.2-0.40.20.3-0.3-0.20.1-0.1-0.0-0.00.00.1-0.3-0.3-0.3-0.3-0.20.10.1-0.1-0.10.2
Reaction time trials correct on left0.10.20.5-0.50.40.5-0.5-0.50.30.30.20.2-0.2-0.30.20.20.20.20.20.70.7-0.70.2-0.2
Reaction time trials on left0.10.20.5-0.50.40.5-0.5-0.50.30.20.20.2-0.2-0.30.10.10.10.10.20.70.7-0.70.2-0.2
Reaction time mean0.30.61.91.2-1.4-1.11.11.0-0.8-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.60.20.2-0.2-0.50.3
Reaction time mean AUC0.20.21.00.9-1.0-0.70.70.6-0.3-0.2-0.2-0.10.10.2-0.1-0.1-0.1-0.1-0.10.70.7-0.70.0-0.1
Median of all reaction times0.30.51.61.2-1.3-1.11.11.0-0.7-0.6-0.6-0.60.60.6-0.5-0.5-0.5-0.5-0.50.00.0-0.0-0.40.3
Reaction time omissions0.00.10.1-0.20.00.1-0.1-0.1-0.1-0.2-0.2-0.20.20.2-0.4-0.4-0.4-0.4-0.3-0.1-0.10.1-0.30.4
Reaction time false alarm rate0.10.10.1-0.10.00.1-0.00.0-0.1-0.3-0.2-0.20.20.2-0.4-0.4-0.4-0.4-0.3-0.4-0.40.4-0.30.3
Reaction time premature initiation rate0.00.10.20.1-0.4-0.10.10.10.00.10.10.1-0.1-0.10.10.10.10.10.10.50.5-0.50.1-0.1
Reaction time premature initiations0.10.20.8-0.2-0.00.2-0.2-0.20.30.40.40.4-0.4-0.40.30.30.30.30.30.90.9-0.90.4-0.4
Std. dev. reaction times0.20.41.61.0-1.3-0.90.90.8-0.6-0.5-0.4-0.40.40.5-0.4-0.4-0.4-0.4-0.40.50.5-0.5-0.30.2
Reaction time trials completed0.10.20.5-0.50.40.5-0.5-0.50.30.20.20.2-0.2-0.30.10.10.10.10.20.70.7-0.70.2-0.2
Reaction time trials AUC0.10.20.6-0.40.30.4-0.4-0.40.40.30.30.3-0.3-0.40.20.20.20.20.20.80.8-0.80.3-0.3
Run reversals in cocaine runway, females0.10.10.40.6-0.6-0.50.50.5-0.2-0.1-0.0-0.10.10.1-0.1-0.1-0.1-0.1-0.1-0.4-0.40.4-0.0-0.1
Run reversals in cocaine runway, males0.00.00.10.2-0.3-0.10.10.1-0.0-0.0-0.0-0.00.00.00.00.00.00.00.00.00.0-0.00.1-0.1
Latency to leave start box in cocaine runway0.40.50.90.7-1.0-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.1-0.10.1-0.60.6
Latency to leave start box in cocaine runway, F0.10.10.20.2-0.5-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.2-0.20.50.5-0.5-0.20.2
Latency to leave start box in cocaine runway, M1.41.31.81.3-1.3-1.31.31.3-1.2-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-0.9-0.90.9-1.01.0
Std. dev. time between licks in bursts0.20.30.8-0.50.40.4-0.4-0.2-0.3-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.7-0.70.7-0.70.9
Total sessions with >9 infusions1.11.31.61.2-1.3-1.21.21.2-1.2-1.2-1.2-1.11.11.2-1.2-1.2-1.2-1.2-1.2-0.7-0.70.7-1.21.1
Short access day 1 total inactive lever presses0.30.41.41.2-1.1-1.11.01.0-0.7-0.5-0.3-0.30.30.5-0.5-0.5-0.5-0.5-0.5-0.2-0.20.2-0.30.2
Short access day 10 total inactive lever presses0.10.20.30.5-0.6-0.50.50.5-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.40.10.1-0.1-0.40.3
Short access day 1 total infusions0.00.00.10.1-0.2-0.10.10.1-0.1-0.10.00.0-0.00.2-0.1-0.1-0.1-0.1-0.10.30.3-0.3-0.10.1
Short access day 10 total infusions0.00.00.3-0.1-0.10.1-0.1-0.10.10.00.10.1-0.1-0.00.00.00.00.00.00.50.5-0.50.0-0.0
Short access total infusions0.10.20.7-0.2-0.00.2-0.2-0.20.20.20.30.3-0.3-0.20.20.20.20.20.20.90.9-0.90.2-0.2
Short access day 1 locomotion0.20.20.80.9-0.9-0.80.80.7-0.5-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.40.20.2-0.2-0.30.2
Short access day 10 total locomotion1.01.92.80.9-1.1-1.11.11.2-1.4-1.6-1.6-1.61.61.6-1.6-1.6-1.6-1.6-1.6-0.7-0.70.7-1.61.7
Short access total locomotion0.81.01.70.5-0.7-0.60.70.7-1.0-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.2-1.2-0.2-0.20.2-1.21.3
One hour access (0.3 mA shock)3.33.86.42.5-2.5-2.42.42.3-2.1-1.9-1.9-1.81.81.9-1.9-1.9-1.9-1.9-1.9-1.3-1.31.3-1.71.5
Compulsive drug intake1.82.22.91.7-1.4-1.61.61.6-1.5-1.4-1.4-1.41.41.5-1.4-1.4-1.4-1.4-1.4-1.6-1.61.6-1.31.2
One hour access (shock baseline)0.10.20.90.7-0.9-0.50.50.4-0.2-0.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.0-0.00.70.7-0.70.1-0.2
Social response proportion0.30.41.91.1-1.4-1.00.90.9-0.6-0.5-0.4-0.40.40.5-0.3-0.3-0.3-0.3-0.40.20.2-0.2-0.20.1
Social responses2.43.14.12.0-2.0-2.02.02.0-1.8-1.8-1.7-1.71.71.8-1.7-1.7-1.7-1.7-1.7-1.6-1.61.6-1.61.5
Social time4.86.67.81.9-2.2-2.12.22.3-2.6-2.8-2.7-2.72.72.8-2.8-2.8-2.8-2.8-2.8-2.4-2.42.4-2.82.8
Soleus weight0.00.10.50.4-0.7-0.30.30.3-0.2-0.2-0.1-0.10.10.2-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.00.0
Bone: stiffness2.23.55.52.3-2.2-2.32.32.2-2.0-1.8-1.8-1.91.91.9-1.8-1.8-1.8-1.8-1.8-1.4-1.41.4-1.71.5
Tibialis anterior weight1.03.34.2-1.31.31.4-1.4-1.51.81.81.91.9-1.9-1.81.91.91.91.91.91.91.9-1.92.0-2.1
Time to tail flick, vehicle, before self-admin0.80.81.10.5-0.5-0.60.60.7-0.9-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.01.0-1.01.0
Time to tail flick, vehicle, after self-admin0.20.21.20.7-1.1-0.60.60.5-0.3-0.2-0.2-0.20.20.1-0.2-0.2-0.2-0.2-0.20.60.6-0.6-0.1-0.0
Time to tail flick, test, before self-admin0.30.30.8-0.40.20.2-0.1-0.0-0.4-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.5-0.50.5-0.80.9
Time to tail flick, test, after self-admin0.50.50.6-0.50.50.6-0.6-0.70.70.80.80.8-0.8-0.80.80.80.80.80.80.50.5-0.50.8-0.8
Delta time to tail flick, vehicle, before/after SA0.60.62.30.1-0.40.1-0.1-0.20.40.60.60.6-0.6-0.60.60.60.60.60.61.51.5-1.50.7-0.7
Delta time to tail flick, test, before/after SA0.10.10.40.3-0.1-0.10.10.00.30.50.50.5-0.5-0.50.50.50.50.50.50.10.1-0.10.6-0.6
Tibia length2.97.912.83.6-3.2-3.43.43.3-2.9-2.6-2.7-2.62.62.6-2.6-2.6-2.6-2.6-2.6-2.7-2.72.7-2.32.1
Ambulatory time before self-admin2.84.15.61.1-1.4-1.41.51.6-2.0-2.2-2.2-2.22.22.2-2.2-2.2-2.2-2.2-2.2-2.0-2.02.0-2.32.4
Ambulatory time after self-admin0.91.01.8-0.1-0.1-0.20.20.4-0.8-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-1.4-1.41.4-1.21.3
Bone: tissue strength0.60.61.20.3-0.6-0.40.40.5-0.8-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.4-0.40.4-1.01.1
Total heroin consumption0.00.00.1-0.30.30.2-0.2-0.20.10.00.00.0-0.0-0.00.00.00.00.00.0-0.0-0.00.0-0.00.0
Bone: trabecular number0.10.20.4-0.60.30.5-0.5-0.50.40.30.30.3-0.3-0.30.30.30.30.30.30.70.7-0.70.2-0.2
Bone: trabecular spacing0.00.00.10.10.2-0.10.10.00.10.10.10.1-0.1-0.10.10.10.10.10.1-0.3-0.30.30.2-0.2
Bone: trabecular thickness0.00.00.10.0-0.2-0.00.00.00.10.10.10.1-0.1-0.10.10.10.10.10.10.40.4-0.40.1-0.1
Bone: trabecular tissue density1.21.82.3-1.01.11.1-1.1-1.21.41.51.41.5-1.5-1.51.51.51.51.51.51.11.1-1.11.5-1.5
Water consumed over 24 hours1.01.41.61.1-1.0-1.11.11.1-1.2-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.2-1.2-1.0-1.01.0-1.21.2
Number of responses in last shaping day0.30.31.60.1-0.3-0.0-0.0-0.10.20.30.50.3-0.3-0.30.30.30.30.30.31.31.3-1.30.4-0.4