Hub : Genes

Cdc42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL intron excision ratio chr5_149558007_149567531 0.23 0.13 3.8e-03 0.12 0.09 0.12 0.12 7.2e-04 4.3e-03 7.9e-04 7.1e-04
2 IL intron excision ratio chr5_149556559_149567531 0.22 0.13 8.1e-03 0.1 0.07 0.09 0.09 2.9e-03 1.1e-02 4.4e-03 4.1e-03
3 PL isoform ratio XM_008764287.3 0.03 0.02 4.1e-04 0.01 0.03 0.03 0.03 1.1e-02 3.3e-04 2.3e-04 4.1e-04
4 PL alternative polyA XM_008764287.3 0.03 0.02 1.3e-03 0.03 0.02 0.03 0.02 4.2e-04 1.0e-03 6.6e-04 1.1e-03
5 PL alternative polyA NM_171994.5 0.02 0.02 2.3e-03 0.03 0.02 0.02 0.02 3.9e-04 1.0e-03 1.8e-03 1.1e-03
6 Adipose mRNA stability Cdc42 0.12 0.07 5.0e-08 0.07 0.08 0.07 0.07 1.8e-08 7.2e-09 1.1e-08 1.2e-08
7 Adipose gene expression Cdc42 0.07 0.05 1.3e-04 0.03 0.02 0.02 0.02 6.8e-04 2.4e-03 1.4e-03 2.7e-03
8 Liver mRNA stability Cdc42 0.03 0.03 1.6e-03 0.03 0.02 0.03 0.03 2.6e-04 1.1e-03 4.5e-04 4.6e-04
9 NAcc mRNA stability Cdc42 0.06 0.04 8.6e-03 0.01 -0 -0 0 8.6e-03 5.5e-01 7.9e-01 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.40.72.91.71.5-0.50.3-0.2-0.50.40.40.3
Area under the delay curve0.40.40.60.0-0.40.70.8-0.50.7-0.7-0.7-0.7
BMI with tail0.51.73.31.31.0-0.8-0.40.61.4-1.8-1.8-1.8
BMI without tail0.20.51.41.20.5-0.9-0.91.0-0.3-0.1-0.10.1
Body weight1.66.612.22.92.6-3.5-3.13.4-2.01.61.61.3
Weight adjusted by age0.60.62.3-0.9-1.5-0.0-1.11.1-0.1-0.0-0.00.1
Bone surface0.40.72.81.71.2-0.50.20.2-0.70.50.50.6
Bone volume0.50.82.51.61.2-0.40.3-0.1-1.00.90.90.8
Breakpoint value in progressive ratio session0.60.72.00.60.8-1.3-1.41.1-0.50.40.40.2
Number of licking bursts0.20.21.1-0.7-1.00.4-0.2-0.20.3-0.3-0.3-0.3
Context. condit. distance diff. score0.91.12.91.71.7-1.5-1.00.9-0.30.10.1-0.1
Locomotion velocity, session 10.80.82.01.20.40.81.4-1.30.5-0.7-0.7-0.5
Locomotion distance, session 11.01.33.20.90.61.01.8-1.70.9-1.0-1.0-0.9
Locomotion velocity, session 22.22.55.9-1.6-1.42.42.4-2.40.70.20.2-0.2
Locomotion distance, session 20.50.71.91.41.00.41.2-1.1-0.30.30.30.3
Locomotion velocity, session 31.61.93.10.0-0.11.01.2-1.61.8-1.6-1.6-1.8
Locomotion distance, session 31.41.54.82.12.2-1.5-0.80.60.0-0.4-0.4-0.5
Stereotopy head waving bouts, day 30.60.71.6-1.2-1.21.31.1-0.80.00.10.10.5
Stereotopy head waving duration, day 30.80.93.2-1.8-1.61.20.8-0.40.00.10.10.5
Locomotion velocity, session 71.71.94.32.11.6-2.0-1.71.4-0.80.60.60.3
Locomotion distance, session 70.30.40.90.90.8-0.9-0.70.6-0.40.40.40.2
Stereotopy head waving bouts, day 70.10.10.3-0.10.0-0.3-0.40.50.2-0.2-0.2-0.2
Stereotopy head waving duration, day 70.10.20.3-0.1-0.2-0.2-0.50.5-0.40.60.60.5
Locomotion velocity, session 80.60.71.40.50.20.71.1-1.20.9-0.7-0.7-0.8
Locomotion distance, session 81.11.66.12.52.5-1.2-0.10.10.1-0.4-0.4-0.5
Degree of sensitization distance1.41.44.5-2.0-2.11.30.6-0.5-0.10.70.70.6
Degree of sensitization stereotypy0.70.71.80.50.6-1.2-1.41.3-0.50.60.60.3
Conditioned locomotion1.72.03.9-1.4-2.01.91.3-1.51.2-1.0-1.0-0.9
Cocaine response after cond. corrected1.61.86.3-2.5-2.41.20.2-0.21.0-0.6-0.6-0.7
Cocaine response after cond. not corrected1.01.14.5-2.1-1.90.7-0.30.20.7-0.4-0.4-0.4
Cocaine response before conditioning1.61.92.91.51.6-1.7-1.41.2-1.51.11.11.2
Saline control response0.40.61.30.20.20.00.2-0.21.0-1.2-1.2-1.1
Bone: connectivity density0.30.51.71.21.3-0.8-0.30.3-0.60.30.30.4
Bone: cortical apparent density0.81.03.1-0.20.0-1.2-1.81.5-0.90.70.70.8
Bone: cortical area2.23.27.12.72.7-1.9-1.01.1-1.81.41.41.4
Bone: cortical porosity0.60.61.1-1.0-0.30.80.9-0.9-0.50.80.80.9
Bone: cortical porosity1.11.22.9-1.7-1.21.51.3-1.2-0.20.60.60.7
Bone: cortical thickness1.01.75.92.02.4-1.7-0.80.9-0.80.30.30.4
Bone: cortical thickness0.70.82.21.11.5-0.20.6-0.80.6-1.0-1.0-0.8
Bone: cortical tissue density0.60.82.8-0.5-0.2-1.1-1.71.4-0.70.50.50.6
Condit. Reinf. active minus inactive responses0.70.82.1-1.5-1.20.90.4-0.5-0.40.70.70.8
Condit. Reinf. active-inactive response ratio1.01.13.1-1.7-1.81.00.2-0.4-0.50.80.81.0
Condit. Reinf. active responses1.11.33.2-0.5-0.10.30.3-0.3-1.41.81.81.7
Condit. Reinf. inactive responses1.51.83.61.21.6-0.60.1-0.0-1.61.91.91.6
Incentive salience index mean0.91.12.6-0.6-0.40.50.4-0.6-1.31.51.51.6
Condit. Reinf. lever presses1.52.04.20.81.1-0.30.3-0.4-1.92.02.02.1
Condit. Reinf. active minus inactive responses0.40.51.21.01.1-0.10.6-0.50.6-0.5-0.5-0.8
Condit. Reinf. active-inactive response ratio1.11.11.6-1.2-0.81.21.1-0.91.3-1.0-1.0-1.1
Condit. Reinf. active responses1.41.98.52.92.6-1.10.0-0.1-0.60.40.40.2
Condit. Reinf. inactive responses4.75.716.14.03.5-2.2-0.90.7-2.42.02.01.9
Condit. Reinf. lever presses1.41.95.92.42.4-0.31.0-0.9-0.90.90.90.8
Condit. Reinf. lever reinforcers received1.52.18.22.92.6-1.20.0-0.0-0.90.70.70.5
Conditioned reinforcement - actives0.80.81.30.81.0-0.8-0.50.5-0.91.21.20.8
Conditioned reinforcement - inactives0.60.71.41.11.2-1.1-0.70.7-0.60.80.80.3
Conditioned locomotion1.11.32.11.31.3-1.4-1.21.1-1.10.90.90.9
Patch foraging indifference point 0 sec0.30.52.31.51.3-0.8-0.30.2-0.3-0.2-0.20.0
Patch foraging indifference point AUC0.80.92.31.51.3-1.3-1.10.8-0.50.40.40.0
Delay disc. indifference point, 0s delay0.70.81.70.70.60.61.3-0.91.0-0.8-0.8-1.0
Delay disc. indifference point, 16s delay0.00.00.00.20.00.10.2-0.0-0.00.00.0-0.0
Delay disc. indifference point, 2s delay0.30.40.7-0.2-0.50.50.4-0.30.8-0.7-0.7-0.8
Delay disc. indifference point, 24s delay0.30.30.5-0.7-0.70.50.3-0.3-0.40.60.60.6
Delay disc. indifference point, 4s delay0.20.20.4-0.2-0.60.70.6-0.10.5-0.3-0.3-0.4
Delay disc. indifference point, 8s delay0.50.61.10.3-0.10.50.7-0.60.9-1.1-1.1-0.9
Indifference point function ln k1.92.67.0-1.5-1.42.52.6-2.30.6-0.3-0.30.1
Indifference point function log k1.92.67.0-1.5-1.42.52.6-2.30.6-0.3-0.30.1
Patch foraging total patch changes 0 sec0.30.52.21.51.2-0.60.0-0.1-0.2-0.2-0.2-0.0
Patch foraging total patch changes 12 sec1.62.03.41.91.5-1.8-1.51.4-1.41.11.10.9
Patch foraging total patch changes 18 sec1.41.85.02.21.6-1.6-1.31.0-1.11.01.00.6
Patch foraging total patch changes 24 sec1.21.54.02.01.8-1.6-1.21.10.2-0.4-0.4-0.9
Patch foraging total patch changes 6 sec2.13.17.32.22.4-2.7-2.22.1-0.60.10.1-0.0
Patch foraging time to switch 0 sec0.71.12.9-0.50.1-1.3-1.71.5-0.80.80.80.7
Patch foraging water rate 0 sec1.32.14.2-0.3-1.01.92.1-1.71.5-1.2-1.2-1.4
Patch foraging water rate 12 sec1.42.13.60.70.61.11.9-1.81.6-1.6-1.6-1.6
Patch foraging water rate 18 sec1.01.42.91.00.61.01.7-1.4-1.01.21.21.2
Patch foraging water rate 24 sec1.21.64.4-0.9-1.42.12.0-1.60.5-0.3-0.3-0.0
Patch foraging water rate 6 sec1.92.85.8-0.6-1.02.22.4-2.21.6-1.3-1.3-1.4
Seeking ratio, delayed vs. immediate footshock1.11.22.21.50.9-0.30.20.01.1-1.5-1.5-1.5
Distance traveled before self-admin3.74.08.12.21.9-2.8-2.72.4-1.61.11.11.0
Distance traveled after self-admin2.52.75.92.42.0-2.3-1.91.7-1.20.60.60.7
Extensor digitorum longus weight0.31.12.91.71.50.11.2-0.80.7-0.8-0.8-0.9
Bone: elastic displacement0.10.10.50.20.7-0.10.40.0-0.30.30.30.1
Bone: elastic work0.20.31.11.01.0-0.40.20.1-0.1-0.1-0.1-0.2
Bone: endosteal estimation1.43.15.81.60.8-1.0-0.80.8-2.42.42.42.4
Bone: endosteal perimeter0.91.83.31.81.5-0.40.4-0.2-1.51.61.61.5
Epididymis fat weight0.00.00.10.1-0.2-0.0-0.20.10.3-0.3-0.3-0.3
Delta time in closed arm before/after self-admin0.90.91.9-0.8-0.80.50.2-0.1-1.11.31.31.4
Delta time in open arm before/after self-admin0.20.20.6-0.2-0.1-0.5-0.80.7-0.10.20.20.2
Diff in mean of infusions in LGA sessions0.20.20.80.00.2-0.10.10.0-0.40.90.90.5
Delay discount exponential model param0.30.30.50.10.6-0.7-0.60.4-0.60.60.60.5
Extinction: sum of active levers before priming0.60.61.00.70.9-1.0-0.91.0-0.80.40.40.7
Active lever presses in extinction session 60.40.40.7-0.6-0.2-0.4-0.70.7-0.50.80.80.6
Bone: final force1.42.35.52.42.0-1.9-1.31.2-1.40.90.90.9
Bone: final moment1.42.36.62.62.3-1.8-1.11.0-1.30.80.80.8
Food consumed during 24 hour testing period0.30.41.8-0.1-0.2-0.7-1.11.3-0.40.20.20.3
Glucose1.11.76.1-0.8-1.0-1.3-2.52.40.00.10.1-0.3
Heart weight0.60.93.5-0.00.1-1.2-1.61.90.1-0.5-0.5-0.4
Delay discount hyperbolic model param0.30.40.50.10.6-0.7-0.70.4-0.70.70.70.7
Intermittent access intake day 1-15 change0.70.72.61.61.4-0.30.6-0.7-0.40.30.30.3
Intermittent access intake escalation0.70.71.31.20.9-0.10.5-0.6-0.90.90.90.9
Intermittent access intake escalation 20.90.81.60.70.60.20.7-0.7-1.11.31.31.2
Intermitt. access day 1 inactive lever presses3.03.25.61.81.7-2.4-2.21.9-1.91.31.31.4
Intermitt. access day 15 inactive lever presses1.21.32.01.11.0-1.3-1.21.0-1.41.11.11.1
Intermitt. access escalation Index1.51.33.11.31.8-1.1-0.40.30.8-1.3-1.3-1.2
Intermittent access day 1 total infusions2.42.87.11.41.4-2.5-2.72.5-0.90.80.80.4
Intermittent access day 15 total infusions2.73.05.22.12.1-2.3-1.91.5-1.51.31.31.1
Intermittent access terminal intake (last 3 days)2.32.53.82.01.8-1.9-1.51.1-1.61.51.51.2
Intermittent access total infusions2.02.24.41.61.6-2.1-1.91.6-1.21.01.00.8
Intermittent access day 1 locomotion0.40.50.90.80.7-0.6-0.40.40.7-0.7-0.7-1.0
Intermittent access day 15 total locomotion0.10.10.20.40.3-0.10.1-0.0-0.20.40.40.3
Intermittent access total locomotion0.50.51.81.31.3-0.9-0.50.4-0.1-0.0-0.0-0.2
Intermittent access standard deviation2.22.34.22.12.0-1.8-1.21.4-1.41.11.11.1
Left kidney weight5.214.635.63.02.3-5.1-5.36.0-3.32.42.42.4
Right kidney weight2.67.319.11.21.2-3.5-3.94.4-2.41.81.81.9
Cocaine induced anxiety0.91.02.5-0.6-0.50.1-0.20.2-1.31.41.41.6
Post-drug Anxiety0.91.02.6-0.9-0.91.61.6-1.50.2-0.0-0.00.2
Baseline Anxiety3.33.55.60.10.11.42.0-1.92.4-2.4-2.4-2.4
Tail length2.26.611.40.90.5-1.9-2.22.5-3.43.33.33.3
Length with tail2.38.311.81.51.6-3.1-3.23.4-3.23.23.22.8
Length without tail1.12.45.41.52.0-2.3-1.82.0-0.90.80.80.5
Times rat made contact with spout0.10.10.3-0.5-0.2-0.3-0.50.30.1-0.5-0.5-0.1
Lifetime Intake1.71.93.41.31.4-1.9-1.71.5-1.21.21.20.8
Liver weight, left3.86.19.91.81.3-2.1-2.12.1-3.13.03.03.0
Liver weight, right2.23.65.31.91.8-2.3-2.01.9-2.01.71.71.6
Locomotor activity1.93.09.63.12.6-2.2-1.41.4-0.90.60.60.3
Locomotor testing distance1.01.75.32.32.0-1.8-1.11.1-0.60.30.30.2
Locomotor testing rearing1.52.37.52.72.5-1.9-1.00.9-0.80.60.60.4
Locomotion in novel chamber4.05.08.22.32.5-1.7-0.80.92.2-2.8-2.8-2.9
Locomotion in novel chamber post-restriction0.40.41.21.01.1-0.8-0.30.5-0.50.40.40.6
Fecal boli incidents, locomotor time 13.84.18.91.82.6-3.0-2.32.8-1.50.90.91.0
Change in fecal boli incidents, locomotor task5.45.19.4-2.4-3.03.12.2-2.52.0-1.3-1.3-1.5
Time >=10cm from walls, locomotor time 10.80.82.90.40.1-1.3-1.71.6-0.40.00.00.1
Bouts of movement, locomotor time 11.21.32.7-1.0-0.80.4-0.0-0.21.5-1.6-1.6-1.6
Total resting periods, locomotor time 11.01.12.2-1.0-0.90.3-0.20.01.4-1.5-1.5-1.4
Rest time, locomotor task time 11.41.64.3-2.0-2.1-0.0-1.21.40.6-0.8-0.8-0.5
Distance moved, locomotor task time 10.70.82.51.51.60.00.9-1.20.3-0.0-0.0-0.5
Vertical activity count, locomotor time 11.51.64.92.22.20.01.3-1.6-0.00.20.2-0.1
Time >=10cm from walls, locomotor time 20.60.72.0-0.3-0.3-0.9-1.41.20.3-0.8-0.8-0.6
Bouts of movement, locomotor time 21.31.42.8-1.7-1.71.00.4-0.21.3-1.2-1.2-1.2
Total resting periods, locomotor time 21.92.04.7-2.1-2.21.30.4-0.21.5-1.2-1.2-1.3
Rest time, locomotor task time 21.11.33.7-1.9-1.8-0.1-1.31.40.6-0.5-0.5-0.5
Distance moved, locomotor task time 20.60.72.21.51.5-0.60.1-0.3-0.60.60.60.5
Vertical activity count, locomotor time 21.31.44.52.12.1-0.30.8-1.1-0.70.80.80.6
Light reinforcement 10.30.62.11.31.5-0.9-0.40.3-0.2-0.2-0.2-0.1
Light reinforcement 20.60.71.60.60.9-0.20.2-0.30.9-1.3-1.3-1.1
Bone: marrow area1.43.05.71.50.8-1.0-0.80.8-2.42.32.32.4
Bone: maximum diameter1.83.27.02.72.3-1.6-0.70.7-2.01.81.81.7
Bone: maximum force1.73.07.52.72.4-1.7-0.90.8-1.81.31.31.4
Bone: maximum moment1.83.29.03.02.7-1.7-0.70.6-1.81.31.31.4
Mean time between licks in bursts0.30.41.30.1-0.20.91.1-1.10.4-0.2-0.2-0.3
Mean num. licks in bursts0.20.30.70.20.8-0.8-0.50.7-0.50.20.20.4
Cd content in liver1.11.22.71.61.6-1.3-0.80.70.5-1.0-1.0-0.9
Co content in liver0.30.41.70.81.3-0.40.3-0.0-0.50.50.50.5
Cu content in liver0.20.20.4-0.6-0.60.1-0.20.10.6-0.5-0.5-0.6
Fe content in liver0.30.41.10.60.60.51.0-1.00.3-0.3-0.3-0.2
K content in liver0.20.20.3-0.5-0.60.50.3-0.50.5-0.4-0.4-0.4
Mg content in liver0.20.20.4-0.1-0.2-0.2-0.50.20.5-0.7-0.7-0.6
Mn content in liver0.30.30.50.60.5-0.4-0.3-0.2-0.70.70.70.7
Na content in liver0.90.92.71.61.4-0.30.5-0.3-0.90.90.90.9
Rb content in liver0.60.82.5-0.20.2-1.3-1.61.6-0.50.30.30.3
Se content in liver1.31.64.8-2.0-2.21.10.2-0.11.2-1.0-1.0-1.0
Sr content in liver1.11.02.81.71.50.31.5-1.1-0.30.30.30.3
Zn content in liver1.51.74.11.51.4-2.0-1.81.7-0.5-0.0-0.00.0
Bone: minimum diameter2.75.08.71.31.3-1.6-1.41.6-3.02.92.92.9
Time in familiar zone, hab. session 10.60.61.40.20.3-1.0-1.11.20.4-0.7-0.7-0.7
Time in novel zone, hab. session 10.00.00.1-0.3-0.10.10.1-0.10.30.00.0-0.2
Total zone transitions, hab. session 10.30.41.61.01.2-0.30.4-0.4-0.30.30.30.2
Total locomotion distance, hab. session 10.50.71.91.11.4-0.20.6-0.3-0.80.90.90.8
Locomotion velocity, hab. session 10.60.91.30.81.10.21.0-0.8-1.01.11.11.1
Time in familiar zone, hab. session 20.20.20.50.30.5-0.4-0.30.3-0.60.70.70.5
Time in novel zone, hab. session 20.90.91.5-0.7-1.00.80.6-0.61.2-1.1-1.1-1.1
Total zone transitions, hab. session 20.91.13.61.91.40.41.4-1.40.1-0.1-0.1-0.2
Total locomotion distance, hab. session 20.91.13.01.41.30.71.7-1.70.1-0.2-0.2-0.1
Locomotion velocity, hab. session 20.91.23.11.81.60.41.5-1.5-0.20.10.10.1
Novel to familiar place preference ratio0.40.41.2-0.8-0.9-0.4-1.01.1-0.0-0.0-0.00.0
Novelty place preference0.50.61.6-0.7-0.8-0.6-1.21.3-0.40.30.30.4
Time in novel zone, NPP test0.60.62.0-0.7-0.9-0.6-1.31.4-0.20.00.00.1
Total zone transitions, NPP test0.50.82.21.10.70.71.4-1.50.4-0.4-0.4-0.3
Total locomotion distance, NPP test0.50.72.00.90.70.71.4-1.3-0.40.20.20.5
Locomotion velocity, NPP test0.71.02.91.00.90.81.7-1.6-0.50.40.40.6
Intraocular pressure0.60.83.61.61.9-0.9-0.1-0.0-0.0-0.4-0.4-0.3
Delta distance traveled before/after self-admin0.10.10.20.30.3-0.00.1-0.1-0.30.20.20.5
Delta ambulatory time before/after self-admin0.00.00.1-0.10.00.20.3-0.3-0.10.10.10.2
Parametrial fat weight0.40.83.0-1.5-1.71.10.5-0.30.3-0.2-0.2-0.0
Pavlov. Cond. lever latency0.70.81.9-0.5-0.6-0.8-1.41.40.7-0.8-0.8-0.9
Pavlov. Cond. magazine entry latency0.20.31.00.81.0-0.7-0.30.4-0.30.40.40.2
Pavlov. Cond. change in total contacts0.50.51.60.40.60.71.3-1.2-0.10.30.30.3
Pavlov. Cond. index score0.40.51.00.91.0-0.10.5-0.4-0.70.90.90.8
Pavlov. Cond. latency score0.40.50.90.80.90.10.7-0.6-0.70.70.70.7
Pavlov. Cond. lever contacts1.11.33.70.40.41.21.9-1.8-0.60.90.90.9
Pavlov. Cond. magazine entry number1.41.73.8-1.8-1.91.50.9-0.91.2-1.1-1.1-0.9
Pavlov. Cond. intertrial magazine entries3.34.010.3-3.1-3.22.71.7-1.71.3-0.5-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.30.30.50.50.60.20.7-0.6-0.40.70.70.5
Pavlov. Cond. response bias0.70.81.81.31.3-0.30.4-0.4-0.91.11.10.9
Pavlov. Cond. lever latency0.91.24.4-2.1-2.00.6-0.40.50.6-0.6-0.6-0.5
Pavlov. Cond. magazine entry latency0.60.72.60.0-0.11.21.6-1.3-0.00.50.50.3
Pavlov. Cond. change in total contacts1.21.64.12.02.0-0.50.6-0.7-1.11.21.21.1
Pavlov. Cond. index score0.60.71.81.31.20.31.2-1.1-0.20.50.50.3
Pavlov. Cond. latency score0.50.61.71.11.10.51.3-1.20.00.20.20.1
Pavlov. Cond. lever contacts1.01.44.72.22.0-0.80.1-0.1-0.90.90.90.7
Pavlov. Cond. magazine entry number0.20.20.8-0.9-0.80.0-0.50.30.0-0.3-0.3-0.0
Pavlov. Cond. intertrial magazine entries0.81.15.3-1.5-2.30.8-0.30.3-0.40.50.50.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.91.41.20.31.2-1.1-0.30.60.60.4
Pavlov. Cond. response bias0.71.03.31.81.6-0.30.7-0.6-0.60.80.80.6
Time in closed arm before self-admin2.63.06.61.91.7-2.6-2.52.3-1.10.50.50.5
Time in closed arm after self-admin1.51.52.60.0-0.1-0.8-1.21.1-1.61.61.61.6
Time in open arm before self-admin0.60.61.8-0.6-0.11.11.3-1.30.6-0.4-0.4-0.4
Time in open arm after self-admin0.70.82.2-1.5-1.21.10.7-0.60.7-0.4-0.4-0.5
Bone: periosteal estimation2.24.67.12.62.1-1.7-1.11.1-2.72.42.42.4
Bone: periosteal perimeter2.33.98.12.82.7-1.7-0.60.8-2.12.02.01.8
Bone: post-yield work0.60.82.00.50.2-0.0-0.0-0.1-1.21.31.31.4
Progressive ratio test 1 active lever presses0.80.81.70.81.0-1.3-1.21.1-0.40.60.60.1
Progressive ratio test 1 breakpoint0.70.81.81.11.2-1.3-1.11.1-0.10.20.2-0.3
Progressive ratio test 1 inactive lever presses0.80.91.50.71.0-1.2-1.01.2-0.80.80.80.5
Progressive ratio test 2 active lever presses2.22.33.81.41.6-1.9-1.71.8-1.41.41.41.0
Progressive ratio test 2 breakpoint2.42.74.31.31.6-2.1-1.91.9-1.51.51.51.1
Progressive ratio test 2 inactive lever presses3.43.96.31.31.7-2.5-2.42.5-1.81.91.91.4
Incentive Sensitization - Responses3.33.44.81.51.7-2.2-1.91.9-2.01.71.71.7
Incentive Sensitization - Breakpoint3.13.14.61.41.6-2.1-1.91.9-2.01.61.61.6
Sum of active levers in priming session hrs 5-60.10.10.50.20.1-0.5-0.70.50.0-0.1-0.1-0.2
Progressive ratio0.30.30.7-0.40.1-0.4-0.40.5-0.70.80.80.6
Food seeking constrained by brief footshock1.21.53.1-0.6-0.6-1.0-1.81.7-1.31.11.11.3
Seeking ratio, punishment vs. effort0.00.10.10.1-0.3-0.1-0.30.3-0.30.00.00.4
Retroperitoneal fat weight0.41.52.5-0.9-0.91.10.9-1.01.6-1.4-1.4-1.4
Reaction time number correct0.71.01.7-1.3-1.11.31.1-1.00.8-0.7-0.7-0.5
Reaction time mean minus median1.01.32.20.80.5-1.2-1.31.50.9-1.3-1.3-1.3
Reaction time mean minus median AUC1.31.73.90.90.6-1.6-1.82.00.6-1.1-1.1-1.1
Reaction time num false alarms0.10.10.50.70.4-0.4-0.40.20.10.00.0-0.3
Reaction time num false alarms AUC0.10.10.30.60.4-0.1-0.0-0.10.3-0.1-0.1-0.4
Reaction time trials correct on left0.71.01.7-1.3-1.11.31.1-1.00.8-0.7-0.7-0.5
Reaction time trials on left0.71.01.8-1.3-1.21.31.1-1.00.8-0.7-0.7-0.5
Reaction time mean0.20.30.70.80.3-0.7-0.70.9-0.20.20.20.0
Reaction time mean AUC0.10.10.20.4-0.1-0.2-0.30.40.2-0.2-0.2-0.3
Median of all reaction times0.10.10.30.3-0.2-0.0-0.10.3-0.40.60.60.4
Reaction time omissions0.00.00.20.40.0-0.1-0.10.40.2-0.0-0.0-0.3
Reaction time false alarm rate0.20.31.11.00.7-0.6-0.50.3-0.00.10.1-0.2
Reaction time premature initiation rate0.40.61.2-0.70.20.71.1-1.00.8-0.5-0.5-0.7
Reaction time premature initiations0.91.22.4-1.2-0.31.21.6-1.51.1-0.8-0.8-0.9
Std. dev. reaction times0.60.81.30.90.4-0.9-0.91.10.7-1.0-1.0-1.1
Reaction time trials completed0.71.01.8-1.3-1.21.31.1-1.00.8-0.7-0.7-0.5
Reaction time trials AUC0.50.81.5-1.2-1.21.20.9-0.80.6-0.5-0.5-0.3
Run reversals in cocaine runway, females0.50.50.80.70.8-0.9-0.70.80.3-0.4-0.4-0.8
Run reversals in cocaine runway, males1.41.33.30.30.2-1.5-1.81.80.6-1.0-1.0-1.0
Latency to leave start box in cocaine runway0.50.51.1-1.0-0.91.10.8-0.90.3-0.1-0.1-0.0
Latency to leave start box in cocaine runway, F0.30.30.6-0.1-0.20.40.5-0.40.6-0.8-0.8-0.7
Latency to leave start box in cocaine runway, M1.91.84.6-2.1-1.91.91.3-1.3-0.10.70.70.7
Std. dev. time between licks in bursts0.30.41.51.11.2-0.20.4-0.6-0.30.40.40.1
Total sessions with >9 infusions1.92.13.01.51.5-1.3-0.90.9-1.71.71.71.5
Short access day 1 total inactive lever presses0.30.41.70.91.3-0.40.30.3-0.30.40.40.2
Short access day 10 total inactive lever presses1.41.63.61.71.7-1.9-1.51.5-0.80.10.10.3
Short access day 1 total infusions1.61.73.41.51.6-1.8-1.51.6-0.80.70.70.4
Short access day 10 total infusions1.11.23.00.91.1-1.7-1.61.7-0.50.30.30.1
Short access total infusions0.80.91.70.70.9-1.3-1.31.3-0.60.70.70.4
Short access day 1 locomotion0.30.30.50.60.7-0.10.2-0.40.6-0.5-0.5-0.7
Short access day 10 total locomotion1.11.32.61.61.4-1.5-1.21.20.3-0.8-0.8-0.7
Short access total locomotion0.50.51.01.00.9-0.7-0.50.40.5-0.6-0.6-0.8
One hour access (0.3 mA shock)2.73.25.62.42.3-2.1-1.41.1-1.71.61.61.3
Compulsive drug intake1.81.83.30.80.7-1.0-1.00.7-1.81.81.81.7
One hour access (shock baseline)1.11.24.21.92.1-1.5-0.80.6-0.2-0.2-0.2-0.3
Social response proportion0.30.31.2-1.1-0.90.3-0.10.10.4-0.4-0.4-0.4
Social responses0.60.83.11.51.8-1.1-0.40.50.1-0.1-0.1-0.4
Social time0.10.10.40.10.00.40.5-0.6-0.10.30.30.2
Soleus weight1.03.012.73.63.4-0.81.1-0.9-0.1-0.2-0.2-0.3
Bone: stiffness2.03.16.82.62.1-1.7-1.10.9-2.01.61.61.7
Tibialis anterior weight0.72.58.32.82.9-0.90.6-0.50.7-1.2-1.2-1.2
Time to tail flick, vehicle, before self-admin2.02.03.1-1.0-0.71.31.3-1.61.8-1.6-1.6-1.6
Time to tail flick, vehicle, after self-admin0.50.61.7-1.3-1.00.4-0.2-0.2-0.70.60.61.0
Time to tail flick, test, before self-admin0.40.41.80.71.3-0.60.00.00.4-0.5-0.5-0.5
Time to tail flick, test, after self-admin0.60.61.6-0.10.0-0.3-0.50.7-1.21.01.01.3
Delta time to tail flick, vehicle, before/after SA1.21.22.0-0.1-0.1-0.8-1.11.1-1.41.41.41.4
Delta time to tail flick, test, before/after SA1.00.91.8-0.6-1.10.80.4-0.4-1.01.11.11.4
Tibia length0.92.53.41.71.5-1.4-1.01.0-1.91.91.91.7
Ambulatory time before self-admin3.13.25.22.01.6-2.3-2.21.9-1.81.41.41.4
Ambulatory time after self-admin2.83.15.02.21.8-2.1-1.81.6-1.71.41.41.4
Bone: tissue strength0.20.20.70.80.5-0.10.2-0.2-0.40.40.40.4
Total heroin consumption0.70.92.10.70.9-1.4-1.41.30.2-0.5-0.5-0.6
Bone: trabecular number0.20.41.31.10.90.00.6-0.70.3-0.3-0.3-0.4
Bone: trabecular spacing0.40.52.7-1.6-1.00.50.1-0.10.4-0.2-0.2-0.2
Bone: trabecular thickness1.01.21.61.20.6-1.2-1.21.2-1.31.11.11.0
Bone: trabecular tissue density0.40.60.90.30.6-0.8-0.80.7-0.90.90.90.9
Water consumed over 24 hours0.20.20.5-0.7-0.70.50.2-0.1-0.20.60.60.3
Number of responses in last shaping day0.20.20.80.40.9-0.6-0.30.30.3-0.1-0.1-0.4