Hub : Genes

Cd63

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Cd63 0.09 0.06 8.9e-06 0.05 0.03 0.03 0.04 8.8e-06 5.1e-04 3.5e-04 6.5e-05
2 Adipose gene expression Cd63 0.54 0.27 0.0e+00 0.17 0.17 0.17 0.17 2.1e-18 8.3e-19 2.0e-18 5.1e-19
3 Brain gene expression Cd63 0.12 0.07 2.6e-07 0.02 0.06 0.06 0.06 3.4e-03 1.5e-06 1.1e-06 3.4e-06
4 NAcc alternative TSS NM_017125.3 0.02 0.02 5.8e-03 0.01 0 0 0.01 2.4e-02 1.1e-01 3.4e-01 3.8e-02
5 Liver isoform ratio NM_017125.3 0.05 0.04 4.2e-06 0.04 0.04 0.02 0.04 8.7e-06 4.5e-05 8.6e-04 2.0e-05
6 Liver isoform ratio XM_008765024.2 0.05 0.03 1.9e-05 0.04 0.03 0.02 0.03 4.8e-05 2.3e-04 3.4e-03 1.1e-04
7 Liver gene expression Cd63 0.23 0.15 0.0e+00 0.17 0.18 0.18 0.18 8.8e-19 3.5e-19 2.9e-19 3.5e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density3.25.37.4-1.01.6-2.22.7-2.72.7-2.6
Area under the delay curve0.20.20.50.20.3-0.70.4-0.40.4-0.5
BMI with tail2.68.323.54.8-4.5-3.6-0.60.7-0.70.7
BMI without tail0.71.53.71.9-1.9-0.9-0.90.8-0.80.8
Body weight0.52.17.02.6-2.1-1.7-0.50.4-0.40.5
Weight adjusted by age0.30.30.50.4-0.40.5-0.50.7-0.70.7
Bone surface6.311.115.5-2.02.5-2.53.9-3.93.9-3.9
Bone volume6.511.015.5-1.82.3-2.83.9-3.93.9-3.8
Breakpoint value in progressive ratio session0.70.82.3-1.21.01.5-0.60.2-0.20.4
Number of licking bursts2.32.65.62.4-2.3-0.7-1.31.4-1.41.3
Context. condit. distance diff. score0.10.10.30.5-0.6-0.2-0.30.2-0.20.3
Locomotion velocity, session 11.41.52.2-0.10.6-1.41.5-1.41.4-1.4
Locomotion distance, session 12.02.53.5-1.01.3-1.11.8-1.91.9-1.8
Locomotion velocity, session 23.23.74.9-1.82.0-0.62.2-2.12.1-2.1
Locomotion distance, session 23.14.36.9-2.12.6-0.42.2-2.12.1-2.1
Locomotion velocity, session 31.51.84.9-2.22.11.80.2-0.20.2-0.2
Locomotion distance, session 30.10.10.2-0.00.10.4-0.20.3-0.30.2
Stereotopy head waving bouts, day 32.52.97.9-2.82.61.50.9-1.01.0-1.0
Stereotopy head waving duration, day 31.82.26.8-2.62.01.40.7-0.70.7-0.8
Locomotion velocity, session 70.30.30.4-0.60.6-0.10.6-0.60.6-0.6
Locomotion distance, session 70.50.60.90.4-0.70.5-0.90.9-0.90.9
Stereotopy head waving bouts, day 71.51.72.4-1.21.6-0.41.3-1.41.4-1.4
Stereotopy head waving duration, day 71.82.22.8-1.21.6-0.71.5-1.61.6-1.7
Locomotion velocity, session 82.93.44.3-1.52.1-0.92.0-2.02.0-2.0
Locomotion distance, session 80.30.40.7-0.60.9-0.10.7-0.70.7-0.7
Degree of sensitization distance0.20.20.40.6-0.6-0.6-0.00.0-0.00.0
Degree of sensitization stereotypy0.70.71.10.10.4-1.10.9-1.01.0-1.0
Conditioned locomotion2.02.32.81.6-1.70.4-1.61.7-1.71.6
Cocaine response after cond. corrected2.52.84.82.1-2.20.2-1.41.7-1.71.6
Cocaine response after cond. not corrected2.83.15.12.1-2.30.2-1.61.8-1.81.8
Cocaine response before conditioning0.30.41.1-1.01.00.20.3-0.60.6-0.4
Saline control response0.30.41.01.0-0.8-0.3-0.60.5-0.50.5
Bone: connectivity density1.93.04.4-0.81.2-1.62.1-2.02.0-2.0
Bone: cortical apparent density0.50.61.81.2-1.3-0.9-0.30.3-0.30.3
Bone: cortical area1.21.83.40.2-0.1-1.81.5-1.51.5-1.5
Bone: cortical porosity0.40.40.7-0.50.4-0.30.8-0.80.8-0.7
Bone: cortical porosity0.80.91.5-0.30.3-0.91.2-1.11.1-1.1
Bone: cortical thickness0.50.82.50.9-0.9-1.60.6-0.70.7-0.6
Bone: cortical thickness0.50.61.41.0-1.2-0.3-0.70.7-0.70.7
Bone: cortical tissue density0.40.51.41.1-1.2-0.7-0.30.3-0.30.3
Condit. Reinf. active minus inactive responses0.80.92.8-1.71.41.00.5-0.40.4-0.4
Condit. Reinf. active-inactive response ratio0.30.30.9-0.50.11.0-0.40.5-0.50.5
Condit. Reinf. active responses1.92.45.1-2.32.10.71.4-1.31.3-1.3
Condit. Reinf. inactive responses1.92.23.4-1.71.8-0.21.5-1.51.5-1.5
Incentive salience index mean1.21.52.5-1.61.50.21.3-1.11.1-1.1
Condit. Reinf. lever presses2.43.14.8-1.01.5-1.32.2-2.02.0-2.0
Condit. Reinf. active minus inactive responses1.11.44.3-1.30.82.1-0.90.8-0.80.9
Condit. Reinf. active-inactive response ratio1.92.03.5-0.1-0.31.9-1.61.6-1.61.7
Condit. Reinf. active responses0.50.72.1-1.51.01.4-0.10.0-0.00.0
Condit. Reinf. inactive responses0.50.60.8-0.90.90.00.7-0.80.8-0.8
Condit. Reinf. lever presses1.01.34.0-1.51.22.0-0.80.6-0.60.6
Condit. Reinf. lever reinforcers received0.40.62.0-1.10.71.4-0.40.3-0.30.4
Conditioned reinforcement - actives0.60.61.2-0.80.4-0.61.1-0.80.8-0.8
Conditioned reinforcement - inactives1.21.43.01.0-1.70.0-1.21.2-1.21.2
Conditioned locomotion1.41.65.9-2.41.61.20.8-0.60.6-0.7
Patch foraging indifference point 0 sec1.11.74.12.0-2.0-2.00.1-0.20.2-0.1
Patch foraging indifference point AUC0.10.20.5-0.50.70.60.20.1-0.1-0.0
Delay disc. indifference point, 0s delay2.42.76.30.70.1-2.51.8-1.61.6-1.8
Delay disc. indifference point, 16s delay0.10.10.5-0.50.70.30.2-0.20.2-0.3
Delay disc. indifference point, 2s delay0.50.61.40.40.2-1.20.6-0.80.8-0.8
Delay disc. indifference point, 24s delay0.20.20.80.8-0.2-0.90.1-0.10.1-0.1
Delay disc. indifference point, 4s delay1.01.01.3-0.71.2-0.61.1-1.11.1-1.2
Delay disc. indifference point, 8s delay0.40.40.60.8-0.40.1-0.50.7-0.70.7
Indifference point function ln k0.00.10.30.2-0.50.0-0.30.1-0.10.2
Indifference point function log k0.00.10.30.2-0.50.0-0.30.1-0.10.2
Patch foraging total patch changes 0 sec1.01.64.02.0-2.0-1.8-0.1-0.10.10.0
Patch foraging total patch changes 12 sec1.11.53.51.9-1.7-0.6-0.81.0-1.00.9
Patch foraging total patch changes 18 sec0.00.00.10.2-0.1-0.20.10.0-0.00.0
Patch foraging total patch changes 24 sec0.30.31.20.8-0.4-1.10.2-0.30.3-0.3
Patch foraging total patch changes 6 sec0.50.82.21.4-1.5-1.10.10.1-0.10.0
Patch foraging time to switch 0 sec0.40.61.70.3-0.0-1.30.8-0.70.7-0.7
Patch foraging water rate 0 sec0.71.21.81.1-1.40.4-1.21.1-1.11.2
Patch foraging water rate 12 sec1.01.62.51.3-1.60.4-1.41.2-1.21.3
Patch foraging water rate 18 sec2.93.96.30.8-1.32.0-2.52.2-2.22.3
Patch foraging water rate 24 sec4.86.79.12.3-2.61.4-3.02.8-2.82.9
Patch foraging water rate 6 sec1.42.04.3-0.3-0.42.1-1.71.4-1.41.6
Seeking ratio, delayed vs. immediate footshock1.01.22.9-1.71.40.40.6-1.01.0-1.0
Distance traveled before self-admin0.40.41.0-1.01.00.60.3-0.50.5-0.4
Distance traveled after self-admin0.20.20.4-0.60.60.10.4-0.40.4-0.4
Extensor digitorum longus weight2.810.927.55.2-5.0-2.4-2.02.2-2.22.1
Bone: elastic displacement0.00.10.1-0.30.1-0.00.2-0.30.3-0.3
Bone: elastic work0.40.51.40.5-0.3-1.20.6-0.70.7-0.7
Bone: endosteal estimation0.30.71.50.4-0.5-1.20.8-0.80.8-0.8
Bone: endosteal perimeter0.81.72.2-1.31.2-0.41.5-1.51.5-1.4
Epididymis fat weight0.10.10.3-0.20.20.5-0.30.4-0.40.4
Delta time in closed arm before/after self-admin4.34.25.81.5-2.01.4-2.42.3-2.32.3
Delta time in open arm before/after self-admin0.70.72.61.2-0.7-1.60.3-0.30.3-0.3
Diff in mean of infusions in LGA sessions0.70.82.1-1.41.21.40.0-0.00.0-0.0
Delay discount exponential model param0.10.20.4-0.2-0.30.6-0.30.4-0.40.4
Extinction: sum of active levers before priming1.61.64.6-1.10.92.2-1.01.1-1.11.0
Active lever presses in extinction session 60.60.51.4-1.01.20.20.6-0.50.5-0.5
Bone: final force1.32.26.91.4-1.0-2.61.2-1.21.2-1.1
Bone: final moment1.32.16.61.3-0.9-2.61.2-1.21.2-1.1
Food consumed during 24 hour testing period0.10.20.60.8-0.6-0.6-0.00.0-0.0-0.0
Glucose0.71.03.21.8-1.5-1.2-0.30.3-0.30.3
Heart weight0.10.20.20.1-0.40.5-0.40.5-0.50.5
Delay discount hyperbolic model param0.20.20.6-0.4-0.20.8-0.40.4-0.40.5
Intermittent access intake day 1-15 change0.30.31.0-0.70.11.0-0.50.2-0.20.4
Intermittent access intake escalation1.51.52.6-0.0-0.71.6-1.61.2-1.21.4
Intermittent access intake escalation 21.31.33.6-0.4-0.11.9-1.51.0-1.01.2
Intermitt. access day 1 inactive lever presses1.21.31.80.1-0.71.3-1.31.3-1.31.3
Intermitt. access day 15 inactive lever presses0.80.82.9-0.50.21.7-0.80.8-0.80.9
Intermitt. access escalation Index1.61.41.8-1.20.8-0.71.3-1.31.3-1.4
Intermittent access day 1 total infusions0.20.31.30.3-0.3-1.10.4-0.20.2-0.3
Intermittent access day 15 total infusions0.20.20.40.2-0.6-0.1-0.60.4-0.40.4
Intermittent access terminal intake (last 3 days)0.10.20.5-0.2-0.2-0.70.2-0.40.4-0.4
Intermittent access total infusions0.20.20.50.5-0.6-0.7-0.20.1-0.10.1
Intermittent access day 1 locomotion0.00.00.10.1-0.1-0.30.10.2-0.20.1
Intermittent access day 15 total locomotion0.20.20.7-0.80.20.6-0.30.2-0.20.3
Intermittent access total locomotion0.10.10.3-0.60.5-0.10.1-0.20.2-0.2
Intermittent access standard deviation0.20.20.8-0.5-0.10.9-0.30.4-0.40.4
Left kidney weight0.61.82.6-0.40.6-1.41.6-1.61.6-1.6
Right kidney weight0.31.01.8-1.31.10.21.1-0.90.9-1.0
Cocaine induced anxiety1.72.03.4-1.61.80.01.4-1.41.4-1.4
Post-drug Anxiety2.52.73.7-1.11.5-1.01.9-1.91.9-1.9
Baseline Anxiety0.20.20.20.3-0.30.3-0.50.4-0.40.5
Tail length1.44.211.0-3.12.83.3-0.60.4-0.40.4
Length with tail0.51.95.4-2.12.31.60.4-0.50.5-0.5
Length without tail0.40.81.20.10.3-1.01.1-1.01.0-1.1
Times rat made contact with spout0.80.91.91.4-1.3-0.3-0.70.8-0.80.9
Lifetime Intake0.40.41.70.6-0.7-1.30.2-0.30.3-0.3
Liver weight, left0.71.23.11.5-1.8-0.5-0.90.8-0.80.8
Liver weight, right0.20.41.00.9-1.0-1.00.1-0.00.0-0.0
Locomotor activity1.93.06.7-2.62.60.81.2-1.41.4-1.2
Locomotor testing distance0.81.33.2-1.81.60.60.7-0.90.9-0.8
Locomotor testing rearing0.10.20.30.1-0.20.4-0.50.5-0.50.5
Locomotion in novel chamber0.10.10.30.4-0.5-0.2-0.20.1-0.10.1
Locomotion in novel chamber post-restriction1.11.43.9-2.01.81.5-0.0-0.30.3-0.3
Fecal boli incidents, locomotor time 11.21.41.71.3-1.20.2-1.31.2-1.21.2
Change in fecal boli incidents, locomotor task1.81.72.3-1.11.2-0.51.5-1.51.5-1.5
Time >=10cm from walls, locomotor time 11.01.02.20.3-0.0-1.51.1-1.01.0-1.0
Bouts of movement, locomotor time 10.20.20.6-0.50.60.70.10.2-0.20.1
Total resting periods, locomotor time 10.40.41.2-1.01.10.80.2-0.10.1-0.1
Rest time, locomotor task time 10.30.30.9-0.60.90.10.6-0.50.5-0.5
Distance moved, locomotor task time 10.90.92.00.1-0.3-1.41.1-1.01.0-1.0
Vertical activity count, locomotor time 10.40.41.70.8-1.3-0.4-0.40.4-0.40.4
Time >=10cm from walls, locomotor time 20.70.71.61.1-1.3-0.4-0.80.7-0.70.7
Bouts of movement, locomotor time 21.21.32.3-0.81.2-0.41.5-1.21.2-1.2
Total resting periods, locomotor time 21.51.62.8-0.91.3-0.61.7-1.31.3-1.4
Rest time, locomotor task time 20.60.70.9-0.40.7-0.71.0-1.01.0-1.0
Distance moved, locomotor task time 20.60.70.90.4-0.70.6-0.81.0-1.01.0
Vertical activity count, locomotor time 21.82.03.21.5-1.80.1-1.41.5-1.51.5
Light reinforcement 11.42.67.3-2.72.41.70.6-0.80.8-0.6
Light reinforcement 20.40.51.4-1.21.00.90.2-0.30.3-0.2
Bone: marrow area0.30.61.40.4-0.5-1.20.8-0.80.8-0.8
Bone: maximum diameter1.42.63.4-1.61.4-0.61.8-1.81.8-1.8
Bone: maximum force1.22.06.41.6-1.2-2.51.0-1.01.0-1.0
Bone: maximum moment1.12.06.21.5-1.2-2.51.0-1.01.0-1.0
Mean time between licks in bursts0.50.62.0-1.00.51.4-0.70.6-0.60.5
Mean num. licks in bursts0.50.61.2-1.11.10.40.7-0.60.6-0.5
Cd content in liver0.10.20.50.7-0.6-0.5-0.00.1-0.1-0.1
Co content in liver0.50.61.9-0.80.61.4-0.60.7-0.70.6
Cu content in liver1.01.32.50.3-0.3-1.61.2-1.31.3-1.2
Fe content in liver0.40.50.90.9-1.0-0.2-0.60.7-0.70.7
K content in liver1.21.11.6-1.01.2-0.31.2-1.11.1-1.1
Mg content in liver1.61.72.5-0.81.3-0.81.6-1.41.4-1.4
Mn content in liver4.95.67.7-1.52.0-1.62.8-2.82.8-2.7
Na content in liver0.40.50.80.20.3-0.90.7-0.80.8-0.7
Rb content in liver1.01.21.80.0-0.0-1.31.3-1.31.3-1.3
Se content in liver0.10.10.2-0.20.3-0.20.4-0.20.2-0.3
Sr content in liver1.51.42.3-0.1-0.41.5-1.31.3-1.31.3
Zn content in liver2.32.55.5-0.60.32.3-1.61.8-1.81.7
Bone: minimum diameter0.61.11.6-0.20.2-1.21.2-1.21.2-1.2
Time in familiar zone, hab. session 11.61.54.0-1.81.72.0-0.20.3-0.30.3
Time in novel zone, hab. session 11.91.95.51.2-1.0-2.31.1-1.21.2-1.2
Total zone transitions, hab. session 11.52.12.8-1.01.5-0.81.7-1.61.6-1.6
Total locomotion distance, hab. session 13.75.36.6-2.12.6-0.82.5-2.52.5-2.5
Locomotion velocity, hab. session 12.73.85.6-2.02.4-0.42.1-2.12.1-2.1
Time in familiar zone, hab. session 22.02.16.7-1.81.42.6-0.80.8-0.80.8
Time in novel zone, hab. session 22.42.47.61.7-1.3-2.81.1-1.01.0-1.0
Total zone transitions, hab. session 21.92.53.80.00.4-1.91.9-1.81.8-1.8
Total locomotion distance, hab. session 21.21.62.0-0.81.3-0.71.4-1.41.4-1.4
Locomotion velocity, hab. session 21.82.43.2-1.01.5-1.01.8-1.81.8-1.8
Novel to familiar place preference ratio2.02.15.71.2-0.6-2.41.3-1.31.3-1.3
Novelty place preference1.61.64.10.9-0.4-2.01.2-1.31.3-1.3
Time in novel zone, NPP test1.61.64.51.1-0.6-2.11.1-1.21.2-1.2
Total zone transitions, NPP test0.60.92.00.60.1-1.41.0-0.90.9-0.9
Total locomotion distance, NPP test1.01.42.1-0.10.7-1.31.4-1.41.4-1.4
Locomotion velocity, NPP test0.91.32.0-0.30.9-1.11.4-1.31.3-1.3
Intraocular pressure1.01.42.30.1-0.01.4-1.51.3-1.31.4
Delta distance traveled before/after self-admin0.00.00.1-0.0-0.0-0.40.2-0.10.1-0.2
Delta ambulatory time before/after self-admin0.30.40.6-0.20.2-0.80.7-0.60.6-0.7
Parametrial fat weight0.10.10.30.1-0.00.5-0.50.3-0.30.4
Pavlov. Cond. lever latency1.01.32.00.6-0.90.8-1.41.3-1.31.4
Pavlov. Cond. magazine entry latency0.50.71.9-1.41.11.30.00.1-0.10.1
Pavlov. Cond. change in total contacts0.00.10.10.1-0.3-0.30.3-0.20.2-0.2
Pavlov. Cond. index score0.60.81.1-1.01.0-0.11.0-0.90.9-0.9
Pavlov. Cond. latency score1.11.41.9-1.11.3-0.41.4-1.31.3-1.3
Pavlov. Cond. lever contacts1.61.93.0-0.40.9-1.21.7-1.61.6-1.6
Pavlov. Cond. magazine entry number0.20.20.70.8-0.7-0.6-0.20.1-0.10.2
Pavlov. Cond. intertrial magazine entries0.60.71.10.2-0.41.0-1.01.0-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.70.81.2-1.11.10.01.0-0.90.9-0.9
Pavlov. Cond. response bias0.30.30.8-0.90.90.60.4-0.30.3-0.3
Pavlov. Cond. lever latency0.50.61.91.3-1.4-0.8-0.10.2-0.20.2
Pavlov. Cond. magazine entry latency0.91.02.7-1.71.60.90.4-0.50.5-0.5
Pavlov. Cond. change in total contacts0.20.31.0-1.00.80.8-0.10.0-0.00.0
Pavlov. Cond. index score0.70.82.4-1.61.41.20.0-0.20.2-0.2
Pavlov. Cond. latency score0.81.02.6-1.61.60.90.3-0.40.4-0.4
Pavlov. Cond. lever contacts0.40.51.3-1.11.01.2-0.30.2-0.20.2
Pavlov. Cond. magazine entry number0.91.13.01.7-1.6-1.0-0.40.5-0.50.5
Pavlov. Cond. intertrial magazine entries0.81.02.11.5-1.4-0.2-1.00.9-0.90.9
Pavlov. Cond. lever-magazine prob. diff.0.81.02.9-1.71.51.10.2-0.30.3-0.3
Pavlov. Cond. response bias0.70.92.3-1.51.31.5-0.30.2-0.20.2
Time in closed arm before self-admin1.11.22.3-0.10.5-1.51.1-1.31.3-1.2
Time in closed arm after self-admin0.10.10.30.3-0.5-0.1-0.4-0.00.00.1
Time in open arm before self-admin0.50.52.1-0.7-0.01.5-0.20.5-0.50.5
Time in open arm after self-admin0.60.71.61.3-1.2-0.6-0.30.7-0.70.6
Bone: periosteal estimation1.12.24.20.3-0.3-2.11.7-1.71.7-1.6
Bone: periosteal perimeter1.32.13.1-0.90.9-1.11.7-1.81.8-1.7
Bone: post-yield work0.10.10.40.7-0.6-0.4-0.00.0-0.00.0
Progressive ratio test 1 active lever presses0.60.61.51.1-1.2-1.2-0.30.3-0.30.3
Progressive ratio test 1 breakpoint0.60.61.91.1-1.1-1.4-0.20.2-0.20.2
Progressive ratio test 1 inactive lever presses0.10.10.4-0.6-0.0-0.00.2-0.30.3-0.2
Progressive ratio test 2 active lever presses0.20.20.60.5-0.6-0.70.2-0.10.1-0.0
Progressive ratio test 2 breakpoint0.30.40.7-0.20.0-0.90.8-0.60.6-0.6
Progressive ratio test 2 inactive lever presses0.20.30.80.0-0.2-0.90.5-0.50.5-0.5
Incentive Sensitization - Responses0.10.10.2-0.50.30.40.3-0.10.1-0.1
Incentive Sensitization - Breakpoint0.20.20.5-0.70.50.30.5-0.40.4-0.4
Sum of active levers in priming session hrs 5-60.10.10.4-0.40.40.6-0.30.1-0.10.1
Progressive ratio0.50.61.71.1-1.3-0.5-0.10.6-0.60.5
Food seeking constrained by brief footshock0.40.61.7-1.01.31.0-0.1-0.10.1-0.0
Seeking ratio, punishment vs. effort0.70.92.6-1.41.61.1-0.3-0.30.3-0.2
Retroperitoneal fat weight1.03.48.83.0-2.9-1.6-1.10.9-0.91.0
Reaction time number correct1.11.62.71.6-1.60.2-1.21.3-1.31.2
Reaction time mean minus median0.50.61.7-1.31.30.80.2-0.40.4-0.4
Reaction time mean minus median AUC2.12.74.1-1.82.0-0.41.6-1.71.7-1.8
Reaction time num false alarms0.30.51.31.1-1.0-0.4-0.30.5-0.50.5
Reaction time num false alarms AUC0.70.91.91.4-1.3-0.2-0.80.8-0.80.9
Reaction time trials correct on left1.11.62.71.6-1.60.2-1.21.3-1.31.2
Reaction time trials on left1.01.42.51.6-1.50.1-1.11.2-1.21.1
Reaction time mean1.11.52.9-1.51.7-0.01.1-1.21.2-1.2
Reaction time mean AUC0.81.11.7-1.11.3-0.41.0-1.11.1-1.2
Median of all reaction times0.81.11.8-1.11.4-0.31.1-1.11.1-1.1
Reaction time omissions0.10.20.3-0.40.2-0.20.4-0.50.5-0.5
Reaction time false alarm rate0.10.10.30.4-0.3-0.60.2-0.10.1-0.1
Reaction time premature initiation rate0.81.13.2-0.80.71.8-0.90.9-0.90.9
Reaction time premature initiations1.52.13.80.1-0.21.9-1.61.7-1.71.7
Std. dev. reaction times0.60.91.7-1.21.30.10.8-0.80.8-0.9
Reaction time trials completed1.01.42.51.6-1.50.1-1.11.2-1.21.1
Reaction time trials AUC1.31.93.01.7-1.70.3-1.41.4-1.41.4
Run reversals in cocaine runway, females1.21.22.6-1.51.60.51.0-0.80.8-0.8
Run reversals in cocaine runway, males1.51.43.8-1.91.70.60.5-0.90.9-0.9
Latency to leave start box in cocaine runway1.71.82.7-0.20.6-1.61.6-1.51.5-1.6
Latency to leave start box in cocaine runway, F3.13.44.8-0.30.9-2.22.1-2.12.1-2.2
Latency to leave start box in cocaine runway, M0.60.61.00.6-0.60.7-0.61.0-1.00.9
Std. dev. time between licks in bursts1.31.52.1-1.41.2-0.11.3-1.31.3-1.4
Total sessions with >9 infusions1.51.72.6-0.70.3-1.61.4-1.51.5-1.4
Short access day 1 total inactive lever presses0.00.00.1-0.3-0.00.0-0.0-0.20.2-0.1
Short access day 10 total inactive lever presses0.60.71.00.1-0.71.0-1.00.9-0.91.0
Short access day 1 total infusions1.41.52.9-0.3-0.0-1.71.0-1.51.5-1.4
Short access day 10 total infusions0.20.31.00.4-0.7-1.00.1-0.10.1-0.2
Short access total infusions1.11.34.40.4-0.5-2.10.8-1.11.1-1.0
Short access day 1 locomotion0.50.50.8-0.80.5-0.60.9-0.70.7-0.8
Short access day 10 total locomotion0.80.92.8-1.40.61.7-0.30.5-0.50.5
Short access total locomotion0.20.20.8-0.90.5-0.20.4-0.40.4-0.4
One hour access (0.3 mA shock)0.10.20.40.7-0.6-0.6-0.00.0-0.00.1
Compulsive drug intake0.10.10.30.6-0.3-0.6-0.2-0.10.1-0.0
One hour access (shock baseline)0.30.30.50.2-0.70.4-0.40.7-0.70.6
Social response proportion0.60.71.7-0.91.30.20.8-0.70.7-0.7
Social responses4.15.213.1-3.53.61.51.5-1.51.5-1.5
Social time0.50.71.71.2-1.3-0.5-0.40.6-0.60.6
Soleus weight2.36.619.34.4-3.9-3.0-0.80.9-0.90.7
Bone: stiffness1.52.36.62.2-1.9-2.60.6-0.50.5-0.5
Tibialis anterior weight0.51.65.02.2-1.8-1.6-0.20.4-0.40.3
Time to tail flick, vehicle, before self-admin3.13.25.0-2.22.0-0.11.3-2.02.0-1.9
Time to tail flick, vehicle, after self-admin0.70.71.80.0-0.11.3-0.81.0-1.00.9
Time to tail flick, test, before self-admin2.01.92.6-1.51.5-0.31.6-1.41.4-1.5
Time to tail flick, test, after self-admin1.01.01.5-0.70.8-0.61.0-1.21.2-1.2
Delta time to tail flick, vehicle, before/after SA3.03.04.22.0-1.70.5-1.52.0-2.01.9
Delta time to tail flick, test, before/after SA0.50.51.00.3-0.20.7-1.00.7-0.70.8
Tibia length0.20.71.7-1.11.31.3-0.10.2-0.20.1
Ambulatory time before self-admin0.10.10.3-0.40.50.40.0-0.20.2-0.1
Ambulatory time after self-admin0.10.10.1-0.30.3-0.10.2-0.30.3-0.3
Bone: tissue strength1.31.23.21.7-1.6-1.80.2-0.20.2-0.2
Total heroin consumption1.01.23.2-1.61.80.80.6-0.70.7-0.7
Bone: trabecular number2.03.13.9-1.42.0-0.92.0-2.02.0-1.9
Bone: trabecular spacing4.15.47.21.3-2.01.9-2.72.7-2.72.6
Bone: trabecular thickness7.58.912.8-1.21.8-2.93.6-3.53.5-3.5
Bone: trabecular tissue density2.94.19.93.0-3.1-1.3-1.51.4-1.41.4
Water consumed over 24 hours1.01.22.70.4-0.2-1.61.1-1.21.2-1.1
Number of responses in last shaping day0.40.41.7-1.30.70.7-0.0-0.20.2-0.2