Hub : Genes

Cd63

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Cd63 0.1 0.06 3.3e-06 0.04 0.06 0.06 0.05 4.3e-05 7.5e-06 2.7e-06 7.9e-06
2 BLA gene expression Cd63 0.06 0.05 4.3e-03 0.05 0.03 0.04 0.04 1.7e-03 6.7e-03 2.0e-03 3.1e-03
3 pVTA gene expression Cd63 0.03 0.03 6.8e-03 0.03 0.01 0.02 0.02 2.8e-03 2.0e-02 8.2e-03 1.5e-02
4 Adipose gene expression Cd63 0.71 0.18 0.0e+00 0.17 0.18 0.18 0.18 5.6e-19 2.0e-19 3.1e-19 6.6e-20
5 Brain mRNA stability Cd63 0.03 0.03 5.5e-03 0 0 0 0 2.0e-01 2.6e-01 2.7e-01 3.3e-01
6 RMTg isoform ratio XM_008765025.4 0.17 0.12 1.5e-03 -0.01 0.01 -0.01 -0 8.1e-01 2.2e-01 9.8e-01 4.1e-01
7 Liver isoform ratio XM_008765025.4 0.05 0.04 2.1e-05 0.04 0.04 0.04 0.04 3.9e-05 6.3e-05 8.8e-05 5.1e-05
8 Liver alternative TSS XM_063263109.1 0.06 0.04 2.2e-06 0.04 0.04 0.03 0.03 3.2e-05 8.2e-05 2.2e-04 1.3e-04
9 Liver alternative TSS XM_008765025.4 0.06 0.05 6.1e-07 0.04 0.04 0.04 0.04 2.3e-05 3.4e-05 5.3e-05 5.8e-05
10 Liver isoform ratio NM_017125.3 0.05 0.04 1.4e-05 0.04 0.04 0.03 0.04 3.8e-05 5.4e-05 1.2e-04 4.2e-05
11 Liver gene expression Cd63 0.22 0.15 0.0e+00 0.16 0.16 0.16 0.16 2.6e-17 2.2e-17 2.9e-17 2.1e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.83.36.0-0.5-0.7-0.50.9-0.51.92.4-2.42.4-2.42.4
Area under the delay curve0.00.10.30.6-0.10.30.20.30.00.2-0.20.2-0.20.2
BMI with tail3.612.729.73.05.35.4-5.25.5-3.4-1.11.1-1.11.1-1.1
BMI without tail0.73.67.92.42.62.8-2.62.8-1.8-0.70.7-0.70.7-0.7
Body weight0.93.98.62.12.42.8-2.42.9-2.0-1.11.1-1.11.1-1.1
Weight adjusted by age0.00.10.10.3-0.10.30.10.1-0.1-0.30.3-0.30.3-0.3
Bone surface4.48.613.7-1.9-1.6-1.61.8-1.63.33.7-3.73.7-3.73.7
Bone volume4.28.313.9-2.1-1.3-1.41.6-1.33.13.7-3.73.7-3.73.7
Breakpoint value in progressive ratio session0.20.41.10.2-1.0-0.90.9-1.10.40.1-0.10.1-0.10.1
Number of licking bursts1.03.05.10.92.12.0-2.22.3-1.9-1.41.4-1.41.4-1.4
Context. condit. distance diff. score0.10.10.30.40.60.5-0.50.5-0.4-0.20.2-0.20.2-0.2
Locomotion velocity, session 11.01.12.1-0.6-0.3-0.30.4-0.21.01.4-1.41.4-1.41.4
Locomotion distance, session 11.92.43.3-1.5-1.0-1.11.0-1.11.71.8-1.81.8-1.81.8
Locomotion velocity, session 23.74.47.4-2.7-1.7-1.91.8-1.92.32.1-2.12.1-2.12.1
Locomotion distance, session 23.44.86.5-1.2-2.5-2.32.5-2.22.62.1-2.12.1-2.12.1
Locomotion velocity, session 31.92.15.7-0.9-2.4-2.22.2-2.31.30.2-0.20.2-0.20.2
Locomotion distance, session 30.10.10.30.6-0.2-0.20.2-0.2-0.1-0.20.2-0.20.2-0.2
Stereotopy head waving bouts, day 33.23.87.7-1.8-2.8-2.72.7-2.72.01.0-1.01.0-1.01.0
Stereotopy head waving duration, day 32.43.06.1-2.3-2.2-2.42.1-2.51.70.8-0.80.8-0.80.8
Locomotion velocity, session 70.30.30.4-0.6-0.4-0.50.4-0.60.60.6-0.60.6-0.60.6
Locomotion distance, session 70.50.60.90.80.60.5-0.70.5-0.9-0.90.9-0.90.9-0.9
Stereotopy head waving bouts, day 71.72.02.6-0.9-1.4-1.31.5-1.31.61.4-1.41.4-1.41.5
Stereotopy head waving duration, day 72.02.53.4-1.0-1.5-1.31.5-1.31.91.7-1.71.7-1.71.7
Locomotion velocity, session 82.83.44.7-0.9-1.8-1.61.9-1.52.22.0-2.02.0-2.02.0
Locomotion distance, session 80.40.60.90.6-1.0-0.70.9-0.70.90.7-0.70.7-0.70.7
Degree of sensitization distance0.20.20.60.10.80.7-0.80.7-0.4-0.00.0-0.00.0-0.0
Degree of sensitization stereotypy0.40.50.90.1-0.20.00.2-0.00.61.0-1.01.0-1.01.0
Conditioned locomotion2.22.63.51.91.31.5-1.41.4-1.8-1.71.7-1.71.7-1.7
Cocaine response after cond. corrected2.13.24.41.21.91.9-2.11.9-2.0-1.71.7-1.71.7-1.7
Cocaine response after cond. not corrected2.53.64.71.62.12.0-2.12.0-2.2-1.81.8-1.81.8-1.8
Cocaine response before conditioning0.40.40.9-0.1-0.7-0.81.0-0.80.60.6-0.60.6-0.60.6
Saline control response0.81.11.81.31.01.3-1.01.3-1.2-0.90.9-0.90.9-0.9
Bone: connectivity density1.11.73.1-0.2-0.5-0.40.6-0.41.41.8-1.81.8-1.81.8
Bone: cortical apparent density0.30.51.60.51.21.1-1.30.9-0.6-0.00.0-0.00.0-0.0
Bone: cortical area0.91.42.6-1.30.30.1-0.30.11.01.6-1.61.6-1.61.6
Bone: cortical porosity0.30.40.6-0.6-0.1-0.20.2-0.30.60.8-0.80.8-0.80.8
Bone: cortical porosity0.70.81.4-0.9-0.0-0.10.0-0.20.91.2-1.21.2-1.21.2
Bone: cortical thickness0.40.71.3-0.41.10.9-1.10.80.10.9-0.90.9-0.90.9
Bone: cortical thickness0.60.81.30.61.10.9-1.21.0-1.1-0.70.7-0.70.7-0.7
Bone: cortical tissue density0.20.41.10.51.00.9-1.10.8-0.5-0.00.0-0.00.0-0.0
Condit. Reinf. active minus inactive responses1.31.54.6-2.1-1.5-1.71.4-1.71.10.4-0.40.4-0.40.4
Condit. Reinf. active-inactive response ratio0.30.31.5-1.2-0.2-0.40.1-0.4-0.1-0.50.5-0.50.5-0.5
Condit. Reinf. active responses2.83.68.3-2.9-2.2-2.32.1-2.31.91.3-1.31.3-1.31.3
Condit. Reinf. inactive responses2.22.83.5-1.6-1.9-1.81.8-1.71.91.6-1.61.6-1.61.6
Incentive salience index mean1.62.14.7-2.2-1.6-1.71.5-1.61.51.1-1.11.1-1.11.1
Condit. Reinf. lever presses1.72.63.5-1.2-1.3-1.21.3-1.01.81.9-1.91.9-1.91.9
Condit. Reinf. active minus inactive responses0.61.02.0-0.7-1.2-1.41.2-1.40.2-0.80.8-0.80.8-0.8
Condit. Reinf. active-inactive response ratio0.81.32.60.7-0.1-0.20.1-0.2-1.0-1.61.6-1.61.6-1.6
Condit. Reinf. active responses0.60.92.4-0.9-1.4-1.61.4-1.50.90.0-0.00.0-0.00.0
Condit. Reinf. inactive responses0.50.71.2-0.8-0.9-1.00.9-0.91.10.8-0.80.8-0.80.8
Condit. Reinf. lever presses0.71.12.6-0.4-1.6-1.61.5-1.60.5-0.50.5-0.50.5-0.5
Condit. Reinf. lever reinforcers received0.40.61.6-0.5-1.1-1.31.0-1.20.5-0.30.3-0.30.3-0.3
Conditioned reinforcement - actives0.10.22.31.50.2-0.0-0.2-0.30.1-0.10.1-0.10.1-0.1
Conditioned reinforcement - inactives0.30.91.71.31.10.9-1.10.5-0.9-0.80.8-0.80.8-0.8
Conditioned locomotion1.31.96.2-0.6-1.5-1.91.5-2.51.60.8-0.80.8-0.80.8
Patch foraging indifference point 0 sec0.82.35.02.22.22.2-2.22.0-0.90.3-0.30.3-0.30.3
Patch foraging indifference point AUC0.20.41.2-1.1-0.9-0.80.8-0.70.3-0.20.2-0.20.2-0.2
Delay disc. indifference point, 0s delay1.21.32.40.80.40.8-0.30.90.71.5-1.51.5-1.51.5
Delay disc. indifference point, 16s delay0.30.42.1-1.5-0.4-0.60.7-0.50.40.3-0.30.3-0.30.3
Delay disc. indifference point, 2s delay0.30.40.70.20.00.30.00.50.30.8-0.80.8-0.80.8
Delay disc. indifference point, 24s delay0.30.53.82.00.50.8-0.20.7-0.3-0.00.0-0.00.0-0.0
Delay disc. indifference point, 4s delay0.80.91.20.1-0.9-0.71.0-0.61.11.1-1.11.1-1.11.1
Delay disc. indifference point, 8s delay0.40.62.11.50.30.8-0.30.8-0.8-0.80.8-0.80.8-0.8
Indifference point function ln k0.00.00.2-0.30.30.0-0.40.1-0.2-0.10.1-0.10.1-0.1
Indifference point function log k0.00.00.2-0.30.30.0-0.40.1-0.2-0.10.1-0.10.1-0.1
Patch foraging total patch changes 0 sec0.72.04.52.12.12.0-2.11.9-0.90.3-0.30.3-0.30.3
Patch foraging total patch changes 12 sec1.41.93.61.71.71.9-1.71.8-1.3-0.80.8-0.80.8-0.8
Patch foraging total patch changes 18 sec0.10.21.51.20.10.50.10.30.00.3-0.30.3-0.30.3
Patch foraging total patch changes 24 sec0.10.41.71.30.60.8-0.40.7-0.00.5-0.50.5-0.50.5
Patch foraging total patch changes 6 sec0.50.82.5-0.51.61.3-1.61.3-0.50.1-0.10.1-0.10.1
Patch foraging time to switch 0 sec0.10.40.60.60.30.4-0.20.40.50.8-0.80.8-0.80.8
Patch foraging water rate 0 sec0.41.42.01.41.21.1-1.31.1-1.4-1.21.2-1.21.2-1.2
Patch foraging water rate 12 sec0.41.62.41.01.41.1-1.41.2-1.5-1.21.2-1.21.2-1.2
Patch foraging water rate 18 sec1.43.25.40.40.90.8-1.00.9-2.1-2.32.3-2.32.3-2.3
Patch foraging water rate 24 sec4.66.69.61.82.22.1-2.32.3-3.1-2.82.8-2.82.8-2.8
Patch foraging water rate 6 sec0.81.12.20.20.1-0.2-0.1-0.3-1.1-1.51.5-1.51.5-1.5
Seeking ratio, delayed vs. immediate footshock1.11.62.9-1.2-1.4-1.61.4-1.71.41.0-1.01.0-1.01.0
Distance traveled before self-admin0.51.02.7-1.6-1.4-1.41.4-1.30.80.4-0.40.4-0.40.4
Distance traveled after self-admin0.20.44.22.1-0.20.20.10.2-0.0-0.00.0-0.00.0-0.0
Extensor digitorum longus weight3.413.625.03.65.04.9-5.05.0-3.9-2.22.2-2.22.2-2.2
Bone: elastic displacement0.10.10.70.80.10.1-0.1-0.00.10.1-0.10.1-0.10.1
Bone: elastic work0.30.40.60.70.70.8-0.70.80.00.6-0.60.6-0.60.6
Bone: endosteal estimation0.20.40.6-0.20.60.5-0.60.50.30.8-0.80.8-0.80.8
Bone: endosteal perimeter0.71.82.4-1.3-1.2-1.21.2-1.31.51.4-1.41.4-1.41.4
Epididymis fat weight0.20.81.50.50.10.2-0.10.2-0.8-1.21.2-1.21.2-1.2
Delta time in closed arm before/after self-admin4.34.05.21.42.01.6-1.91.7-2.3-2.22.2-2.22.2-2.2
Delta time in open arm before/after self-admin0.70.95.22.30.71.2-0.71.1-0.7-0.20.2-0.20.2-0.2
Diff in mean of infusions in LGA sessions0.50.82.4-0.3-1.3-1.51.4-1.50.80.0-0.00.0-0.00.0
Delay discount exponential model param0.00.10.3-0.60.2-0.2-0.3-0.2-0.0-0.20.2-0.20.2-0.2
Extinction: sum of active levers before priming0.40.61.1-0.1-0.8-0.90.8-1.1-0.0-0.80.8-0.80.8-0.8
Active lever presses in extinction session 60.30.30.5-0.6-0.6-0.50.5-0.70.50.5-0.50.5-0.50.5
Bone: final force0.91.41.90.41.31.3-1.21.20.31.4-1.41.4-1.41.4
Bone: final moment0.91.51.90.51.31.3-1.21.20.31.4-1.41.4-1.41.4
Food consumed during 24 hour testing period0.10.20.50.20.70.6-0.70.7-0.4-0.10.1-0.10.1-0.1
Glucose1.11.76.22.51.41.8-1.41.8-1.1-0.40.4-0.40.4-0.4
Heart weight0.20.30.5-0.1-0.2-0.20.2-0.3-0.3-0.70.7-0.70.7-0.7
Delay discount hyperbolic model param0.10.10.4-0.60.0-0.3-0.1-0.4-0.1-0.40.4-0.40.4-0.4
Intermittent access intake day 1-15 change0.00.30.40.3-0.3-0.40.2-0.6-0.2-0.70.7-0.70.7-0.7
Intermittent access intake escalation0.10.30.60.8-0.2-0.30.2-0.5-0.3-0.70.7-0.70.7-0.7
Intermittent access intake escalation 20.10.20.50.4-0.7-0.60.6-0.70.1-0.30.3-0.30.3-0.3
Intermitt. access day 1 inactive lever presses0.11.22.40.50.10.0-0.2-0.1-1.0-1.51.5-1.51.5-1.5
Intermitt. access day 15 inactive lever presses0.10.30.80.3-0.8-0.90.9-0.70.2-0.20.2-0.20.2-0.2
Intermitt. access escalation Index0.20.50.80.6-0.3-0.10.2-0.30.80.9-0.90.9-0.90.9
Intermittent access day 1 total infusions0.20.75.42.30.70.5-0.70.3-0.3-0.40.4-0.40.4-0.4
Intermittent access day 15 total infusions0.10.22.11.40.2-0.1-0.2-0.40.20.0-0.00.0-0.00.0
Intermittent access terminal intake (last 3 days)0.30.53.01.7-0.3-0.50.3-0.70.70.6-0.60.6-0.60.6
Intermittent access total infusions0.40.55.12.30.40.2-0.3-0.10.10.1-0.10.1-0.10.1
Intermittent access day 1 locomotion0.71.37.12.70.70.6-0.70.3-0.7-1.01.0-1.01.0-1.0
Intermittent access day 15 total locomotion0.10.31.81.3-0.0-0.1-0.0-0.7-0.2-0.50.5-0.50.5-0.5
Intermittent access total locomotion0.50.65.32.3-0.00.10.0-0.4-0.1-0.40.4-0.40.4-0.4
Intermittent access standard deviation0.20.92.3-1.0-0.9-1.30.9-1.51.10.6-0.60.6-0.60.6
Left kidney weight0.00.10.20.10.10.2-0.20.3-0.4-0.50.5-0.50.5-0.5
Right kidney weight0.00.30.5-0.6-0.5-0.40.5-0.4-0.1-0.70.7-0.70.7-0.7
Cocaine induced anxiety1.13.15.4-2.3-1.8-1.71.9-1.81.91.6-1.61.6-1.61.6
Post-drug Anxiety3.03.44.6-1.3-1.5-1.21.6-1.52.02.2-2.22.2-2.22.2
Baseline Anxiety0.00.10.50.70.10.1-0.10.2-0.10.1-0.10.1-0.10.1
Tail length0.84.512.0-1.5-3.5-3.33.3-3.31.7-0.00.0-0.00.0-0.0
Length with tail0.41.74.2-1.0-2.0-1.92.0-1.80.6-0.60.6-0.60.6-0.6
Length without tail0.20.91.30.21.11.1-1.01.2-1.0-0.80.8-0.80.8-0.8
Times rat made contact with spout1.21.32.31.11.41.4-1.31.5-1.3-0.90.9-0.90.9-0.9
Lifetime Intake0.70.97.72.80.80.6-0.80.3-0.00.3-0.30.3-0.30.3
Liver weight, left0.20.40.8-0.00.90.8-0.90.9-0.6-0.40.4-0.40.4-0.4
Liver weight, right0.10.20.40.2-0.20.20.20.2-0.3-0.60.6-0.60.6-0.6
Locomotor activity2.64.16.9-2.6-2.5-2.32.6-2.42.01.4-1.41.4-1.41.4
Locomotor testing distance1.02.56.1-2.5-1.7-1.71.9-1.81.61.1-1.11.1-1.11.1
Locomotor testing rearing0.00.10.20.30.10.3-0.00.2-0.3-0.40.4-0.40.4-0.4
Locomotion in novel chamber0.00.00.2-0.40.40.1-0.30.0-0.00.0-0.00.0-0.00.0
Locomotion in novel chamber post-restriction1.03.06.6-2.6-2.5-2.52.4-2.31.30.4-0.40.4-0.40.4
Fecal boli incidents, locomotor time 10.51.21.90.41.21.2-1.01.3-1.4-1.01.0-1.01.0-1.0
Change in fecal boli incidents, locomotor task1.81.92.5-1.5-1.2-1.21.0-1.11.61.5-1.51.5-1.51.5
Time >=10cm from walls, locomotor time 10.50.71.4-0.00.30.3-0.00.20.71.2-1.21.2-1.21.2
Bouts of movement, locomotor time 10.40.52.7-1.7-0.8-0.80.9-0.70.3-0.20.2-0.20.2-0.2
Total resting periods, locomotor time 10.70.82.1-1.5-1.2-1.21.4-1.20.60.0-0.00.0-0.00.0
Rest time, locomotor task time 10.40.61.3-0.2-1.0-0.81.1-0.80.90.7-0.70.7-0.70.7
Distance moved, locomotor task time 10.30.81.5-0.00.50.4-0.60.30.61.2-1.21.2-1.21.2
Vertical activity count, locomotor time 10.10.72.20.21.41.1-1.50.9-0.7-0.30.3-0.30.3-0.3
Time >=10cm from walls, locomotor time 20.41.12.01.41.21.3-1.21.2-1.1-0.80.8-0.80.8-0.8
Bouts of movement, locomotor time 20.41.34.5-2.1-0.7-0.91.0-0.71.11.1-1.11.1-1.11.1
Total resting periods, locomotor time 20.41.64.1-2.0-0.8-0.91.1-0.81.31.3-1.31.3-1.31.3
Rest time, locomotor task time 20.40.70.9-0.4-0.7-0.40.7-0.50.91.0-1.01.0-1.01.0
Distance moved, locomotor task time 20.40.61.11.00.50.5-0.60.3-0.7-0.90.9-0.90.9-0.9
Vertical activity count, locomotor time 21.02.33.11.61.81.6-1.61.4-1.7-1.41.4-1.41.4-1.4
Light reinforcement 10.83.67.8-0.9-2.7-2.62.7-2.81.91.2-1.21.2-1.21.2
Light reinforcement 20.30.71.50.2-1.2-1.21.2-1.20.80.5-0.50.5-0.50.5
Bone: marrow area0.10.30.5-0.20.60.5-0.50.40.20.7-0.70.7-0.70.7
Bone: maximum diameter1.42.84.1-2.0-1.3-1.51.4-1.61.91.7-1.71.7-1.71.7
Bone: maximum force0.71.42.10.71.41.5-1.41.40.01.1-1.11.1-1.11.1
Bone: maximum moment0.71.42.30.81.51.5-1.41.40.01.1-1.11.1-1.11.1
Mean time between licks in bursts0.10.61.4-1.2-1.0-1.10.7-1.20.5-0.30.3-0.30.3-0.3
Mean num. licks in bursts0.20.51.10.3-0.8-0.71.0-0.90.80.6-0.60.6-0.60.6
Cd content in liver0.30.31.7-1.3-0.5-0.70.5-0.80.50.1-0.10.1-0.10.1
Co content in liver0.91.02.2-1.2-1.5-1.51.4-1.50.5-0.40.4-0.40.4-0.4
Cu content in liver0.81.01.7-1.30.20.0-0.1-0.20.81.3-1.31.3-1.31.3
Fe content in liver0.20.30.50.50.70.5-0.70.4-0.6-0.50.5-0.50.5-0.5
K content in liver1.21.11.6-1.1-1.1-1.01.2-1.11.31.0-1.01.0-1.01.0
Mg content in liver1.11.22.6-1.6-1.3-1.31.3-1.11.20.8-0.80.8-0.80.8
Mn content in liver5.36.07.5-2.7-2.0-2.02.1-2.02.72.6-2.62.6-2.62.6
Na content in liver0.60.72.81.7-0.20.50.20.20.40.9-0.90.9-0.90.9
Rb content in liver1.21.34.2-2.00.1-0.20.0-0.31.11.4-1.41.4-1.41.4
Se content in liver0.00.00.4-0.7-0.2-0.20.1-0.10.1-0.00.0-0.00.0-0.0
Sr content in liver0.40.30.80.9-0.10.00.0-0.3-0.3-0.70.7-0.70.7-0.7
Zn content in liver1.51.72.5-1.1-1.1-1.21.0-1.1-0.5-1.61.6-1.61.6-1.6
Bone: minimum diameter0.50.91.7-1.30.0-0.30.0-0.20.91.2-1.21.2-1.21.2
Time in familiar zone, hab. session 11.21.33.6-0.4-1.9-1.81.9-1.80.7-0.30.3-0.30.3-0.3
Time in novel zone, hab. session 11.11.21.80.51.31.3-1.31.20.11.1-1.11.1-1.11.1
Total zone transitions, hab. session 11.52.12.7-0.9-1.3-1.11.2-1.01.61.7-1.71.7-1.71.7
Total locomotion distance, hab. session 13.75.37.4-1.0-2.2-2.02.3-2.02.72.5-2.52.5-2.52.5
Locomotion velocity, hab. session 12.94.25.7-1.1-2.2-1.92.2-1.92.42.1-2.12.1-2.12.1
Time in familiar zone, hab. session 21.41.63.7-1.1-1.8-1.91.7-1.90.4-0.80.8-0.80.8-0.8
Time in novel zone, hab. session 21.61.83.60.91.81.9-1.71.9-0.21.0-1.01.0-1.01.0
Total zone transitions, hab. session 21.41.83.7-0.2-0.00.00.0-0.01.21.9-1.91.9-1.91.9
Total locomotion distance, hab. session 21.11.52.10.1-1.1-0.91.1-0.91.41.4-1.41.4-1.41.4
Locomotion velocity, hab. session 21.72.23.2-0.0-1.3-1.01.3-1.01.71.8-1.81.8-1.81.8
Novel to familiar place preference ratio1.01.31.80.51.11.3-1.01.30.31.3-1.31.3-1.31.3
Novelty place preference0.81.01.60.40.81.0-0.70.90.41.3-1.31.3-1.31.3
Time in novel zone, NPP test0.91.11.50.51.11.2-1.01.10.21.2-1.21.2-1.21.2
Total zone transitions, NPP test0.40.61.10.50.10.4-0.20.50.51.0-1.01.0-1.01.0
Total locomotion distance, NPP test0.81.11.90.9-0.5-0.00.4-0.01.01.4-1.41.4-1.41.4
Locomotion velocity, NPP test0.81.11.80.7-0.8-0.30.7-0.31.11.3-1.31.3-1.31.3
Intraocular pressure0.71.12.00.3-0.00.2-0.00.4-1.1-1.41.4-1.41.4-1.4
Delta distance traveled before/after self-admin0.91.06.42.50.81.1-0.91.0-0.6-0.40.4-0.40.4-0.4
Delta ambulatory time before/after self-admin0.30.53.31.80.60.8-0.70.7-0.10.1-0.10.1-0.10.1
Parametrial fat weight0.10.30.80.60.80.9-0.80.9-0.20.3-0.30.3-0.30.3
Pavlov. Cond. lever latency1.41.72.51.40.90.8-0.80.7-1.4-1.61.6-1.61.6-1.6
Pavlov. Cond. magazine entry latency0.81.02.4-1.5-1.4-1.51.3-1.40.80.2-0.20.2-0.20.2
Pavlov. Cond. change in total contacts0.10.10.8-0.90.30.0-0.30.1-0.10.2-0.20.2-0.20.2
Pavlov. Cond. index score0.81.12.3-1.5-1.0-1.11.0-1.01.00.9-0.90.9-0.90.9
Pavlov. Cond. latency score1.31.72.8-1.7-1.2-1.31.2-1.21.41.3-1.31.3-1.31.3
Pavlov. Cond. lever contacts1.01.32.0-1.1-0.6-0.60.6-0.41.21.4-1.41.4-1.41.4
Pavlov. Cond. magazine entry number0.40.52.01.40.91.0-0.80.8-0.40.0-0.00.0-0.00.0
Pavlov. Cond. intertrial magazine entries0.40.51.00.30.10.2-0.20.1-0.7-1.01.0-1.01.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.02.2-1.5-1.1-1.21.0-1.11.00.8-0.80.8-0.80.8
Pavlov. Cond. response bias0.40.41.5-1.2-0.9-0.90.8-0.80.50.2-0.20.2-0.20.2
Pavlov. Cond. lever latency0.60.92.40.71.61.4-1.51.3-0.9-0.20.2-0.20.2-0.2
Pavlov. Cond. magazine entry latency1.01.43.1-1.7-1.8-1.71.7-1.51.10.4-0.40.4-0.40.4
Pavlov. Cond. change in total contacts0.20.51.5-1.2-0.9-1.10.9-0.90.4-0.10.1-0.10.1-0.1
Pavlov. Cond. index score0.71.22.7-1.5-1.6-1.71.5-1.50.90.1-0.10.1-0.10.1
Pavlov. Cond. latency score0.91.53.2-1.6-1.8-1.81.7-1.61.10.4-0.40.4-0.40.4
Pavlov. Cond. lever contacts0.50.71.9-0.8-1.4-1.31.3-1.20.6-0.10.1-0.10.1-0.1
Pavlov. Cond. magazine entry number1.41.84.62.11.81.9-1.71.7-1.2-0.50.5-0.50.5-0.5
Pavlov. Cond. intertrial magazine entries0.71.53.61.91.41.6-1.31.4-1.1-0.80.8-0.80.8-0.8
Pavlov. Cond. lever-magazine prob. diff.1.01.53.4-1.8-1.7-1.81.7-1.71.10.3-0.30.3-0.30.3
Pavlov. Cond. response bias0.81.12.7-1.2-1.6-1.61.6-1.50.7-0.20.2-0.20.2-0.2
Time in closed arm before self-admin0.40.61.2-0.5-0.2-0.20.2-0.20.81.1-1.11.1-1.11.1
Time in closed arm after self-admin0.20.20.8-0.40.80.5-0.90.4-0.5-0.30.3-0.30.3-0.3
Time in open arm before self-admin0.10.10.7-0.80.1-0.2-0.1-0.20.0-0.10.1-0.10.1-0.1
Time in open arm after self-admin1.82.08.32.91.31.7-1.41.7-1.2-0.70.7-0.70.7-0.7
Bone: periosteal estimation0.61.52.8-1.20.50.2-0.40.20.91.7-1.71.7-1.71.7
Bone: periosteal perimeter1.12.13.6-1.9-0.6-0.80.7-0.81.51.7-1.71.7-1.71.7
Bone: post-yield work0.10.30.80.50.70.9-0.70.9-0.30.0-0.00.0-0.00.0
Progressive ratio test 1 active lever presses0.71.29.73.10.81.0-0.80.6-0.4-0.40.4-0.40.4-0.4
Progressive ratio test 1 breakpoint0.71.39.93.10.91.0-0.90.6-0.4-0.40.4-0.40.4-0.4
Progressive ratio test 1 inactive lever presses0.10.21.21.1-0.3-0.50.3-0.70.30.0-0.00.0-0.00.0
Progressive ratio test 2 active lever presses0.30.44.62.2-0.1-0.10.1-0.40.20.1-0.10.1-0.10.1
Progressive ratio test 2 breakpoint0.40.55.02.2-0.2-0.20.3-0.50.30.1-0.10.1-0.10.1
Progressive ratio test 2 inactive lever presses0.31.19.43.10.20.2-0.1-0.10.50.6-0.60.6-0.60.6
Incentive Sensitization - Responses0.10.21.11.1-0.5-0.60.6-0.60.3-0.00.0-0.00.0-0.0
Incentive Sensitization - Breakpoint0.10.30.70.7-0.7-0.80.8-0.80.50.2-0.20.2-0.20.2
Sum of active levers in priming session hrs 5-60.10.10.10.3-0.3-0.30.3-0.4-0.0-0.10.1-0.10.1-0.1
Progressive ratio0.41.22.50.91.51.4-1.61.3-1.2-0.80.8-0.80.8-0.8
Food seeking constrained by brief footshock0.70.92.5-1.1-1.6-1.41.5-1.10.6-0.00.0-0.00.0-0.0
Seeking ratio, punishment vs. effort0.71.54.1-1.2-2.0-1.82.0-1.51.10.4-0.40.4-0.40.4
Retroperitoneal fat weight1.88.213.83.33.53.7-3.53.6-3.1-2.02.0-2.02.0-2.0
Reaction time number correct0.62.03.01.71.41.3-1.41.6-1.6-1.31.3-1.31.3-1.3
Reaction time mean minus median0.21.23.7-1.9-1.3-1.51.3-1.31.00.4-0.40.4-0.40.4
Reaction time mean minus median AUC0.53.34.3-1.9-1.9-1.91.9-1.82.11.7-1.71.7-1.71.7
Reaction time num false alarms0.40.61.50.81.01.2-1.11.1-0.7-0.40.4-0.40.4-0.4
Reaction time num false alarms AUC0.41.01.91.11.11.4-1.21.3-1.0-0.70.7-0.70.7-0.7
Reaction time trials correct on left0.62.03.01.71.41.3-1.41.6-1.6-1.31.3-1.31.3-1.3
Reaction time trials on left0.51.82.71.71.41.3-1.41.5-1.5-1.21.2-1.21.2-1.2
Reaction time mean1.02.23.6-1.9-1.6-1.81.7-1.61.61.2-1.21.2-1.21.2
Reaction time mean AUC0.61.52.4-1.5-1.2-1.41.2-1.21.41.1-1.11.1-1.11.1
Median of all reaction times1.11.72.3-1.5-1.3-1.41.3-1.31.51.2-1.21.2-1.21.2
Reaction time omissions0.30.50.9-1.0-0.4-0.60.3-0.50.80.8-0.80.8-0.80.8
Reaction time false alarm rate0.10.10.40.20.30.6-0.40.4-0.00.2-0.20.2-0.20.2
Reaction time premature initiation rate0.40.70.91.0-0.9-0.50.9-0.7-0.2-0.90.9-0.90.9-0.9
Reaction time premature initiations0.51.63.11.8-0.20.20.10.1-1.1-1.61.6-1.61.6-1.6
Std. dev. reaction times0.41.42.9-1.7-1.3-1.41.3-1.21.30.9-0.90.9-0.90.9
Reaction time trials completed0.51.82.71.71.41.3-1.41.5-1.5-1.21.2-1.21.2-1.2
Reaction time trials AUC0.72.43.61.91.51.4-1.61.7-1.8-1.41.4-1.41.4-1.4
Run reversals in cocaine runway, females2.02.23.9-1.0-2.0-1.92.0-1.91.71.0-1.11.1-1.11.1
Run reversals in cocaine runway, males2.22.44.0-1.7-1.9-2.01.9-2.01.61.2-1.21.2-1.21.2
Latency to leave start box in cocaine runway0.81.12.1-0.5-0.6-0.00.3-0.11.21.5-1.31.3-1.31.4
Latency to leave start box in cocaine runway, F1.51.93.9-0.6-0.8-0.20.4-0.21.52.0-1.81.8-1.81.8
Latency to leave start box in cocaine runway, M0.20.20.30.30.30.3-0.30.4-0.4-0.50.5-0.50.5-0.5
Std. dev. time between licks in bursts0.91.72.7-1.4-1.2-1.41.2-1.41.61.2-1.21.2-1.21.2
Total sessions with >9 infusions0.40.42.91.70.80.4-0.70.00.10.3-0.30.3-0.30.3
Short access day 1 total inactive lever presses0.10.20.30.5-0.3-0.40.3-0.5-0.1-0.50.5-0.50.5-0.5
Short access day 10 total inactive lever presses0.21.32.5-0.40.50.1-0.50.2-1.2-1.61.6-1.61.6-1.6
Short access day 1 total infusions0.20.31.81.30.80.3-0.7-0.00.10.3-0.30.3-0.30.3
Short access day 10 total infusions0.30.54.42.10.60.3-0.60.1-0.1-0.20.2-0.20.2-0.2
Short access total infusions0.71.08.22.90.90.6-0.90.30.00.4-0.40.4-0.40.4
Short access day 1 locomotion0.10.20.80.8-0.2-0.50.2-0.90.3-0.40.4-0.40.4-0.4
Short access day 10 total locomotion0.31.11.70.9-0.7-0.80.5-1.3-0.2-1.31.3-1.31.3-1.3
Short access total locomotion0.30.42.51.6-0.1-0.20.1-0.80.0-0.50.5-0.50.5-0.5
One hour access (0.3 mA shock)0.20.30.80.90.50.5-0.50.5-0.6-0.40.4-0.40.4-0.4
Compulsive drug intake0.10.20.9-0.9-0.3-0.20.3-0.00.20.4-0.40.4-0.40.4
One hour access (shock baseline)0.10.43.21.80.1-0.0-0.1-0.3-0.1-0.30.3-0.30.3-0.3
Social response proportion0.60.81.8-0.2-1.3-1.01.4-1.00.90.6-0.60.6-0.60.6
Social responses5.06.514.3-1.4-3.8-3.43.8-3.62.81.4-1.41.4-1.41.4
Social time0.71.12.00.41.41.3-1.41.4-1.2-0.70.7-0.70.7-0.7
Soleus weight2.78.018.03.14.24.2-4.04.2-2.6-0.70.7-0.70.7-0.7
Bone: stiffness0.91.63.81.01.91.9-1.91.8-0.40.7-0.70.7-0.70.7
Tibialis anterior weight0.62.04.71.02.22.1-2.12.1-1.4-0.40.4-0.40.4-0.4
Time to tail flick, vehicle, before self-admin1.62.05.2-2.3-1.4-1.41.3-1.51.31.2-1.21.2-1.21.2
Time to tail flick, vehicle, after self-admin0.40.91.7-0.7-0.3-0.30.00.1-0.8-1.31.3-1.31.3-1.3
Time to tail flick, test, before self-admin1.92.15.9-2.4-1.1-1.31.2-1.31.61.3-1.31.3-1.31.3
Time to tail flick, test, after self-admin0.20.20.40.1-0.2-0.20.2-0.20.50.6-0.60.6-0.60.6
Delta time to tail flick, vehicle, before/after SA2.52.73.51.31.31.5-1.51.8-1.9-1.71.7-1.71.7-1.7
Delta time to tail flick, test, before/after SA1.01.33.82.00.50.6-0.50.7-1.2-1.21.2-1.21.2-1.2
Tibia length0.20.62.10.3-1.4-1.11.4-1.00.5-0.30.3-0.30.3-0.3
Ambulatory time before self-admin0.10.20.5-0.7-0.7-0.60.7-0.60.30.1-0.10.1-0.10.1
Ambulatory time after self-admin0.20.44.02.0-0.10.30.10.20.00.1-0.10.1-0.10.1
Bone: tissue strength1.81.94.51.82.02.1-2.01.9-0.80.3-0.30.3-0.30.3
Total heroin consumption1.31.53.5-0.2-1.9-1.61.8-1.61.30.8-0.80.8-0.80.8
Bone: trabecular number1.22.23.0-0.7-1.4-1.11.4-1.01.71.7-1.71.7-1.71.7
Bone: trabecular spacing2.73.96.11.21.41.2-1.41.0-2.2-2.52.5-2.52.5-2.5
Bone: trabecular thickness4.76.511.2-1.9-1.0-1.11.2-0.92.73.3-3.33.3-3.33.3
Bone: trabecular tissue density2.44.18.21.62.82.7-2.92.7-2.1-1.21.2-1.21.2-1.2
Water consumed over 24 hours0.20.50.7-0.30.60.6-0.50.70.30.8-0.80.8-0.80.8
Number of responses in last shaping day0.50.72.50.7-0.9-1.30.9-1.60.5-0.50.5-0.50.5-0.5