Hub : Genes

Cd63

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Cd63 0.1 0.06 3.3e-06 0.04 0.06 0.06 0.05 4.3e-05 7.5e-06 2.7e-06 8.1e-06
2 BLA gene expression Cd63 0.06 0.05 4.3e-03 0.05 0.03 0.04 0.04 1.7e-03 6.7e-03 2.0e-03 3.0e-03
3 pVTA gene expression Cd63 0.03 0.03 6.8e-03 0.03 0.01 0.02 0.02 2.8e-03 2.0e-02 8.2e-03 1.3e-02
4 Adipose gene expression Cd63 0.71 0.18 0.0e+00 0.17 0.18 0.18 0.18 5.6e-19 2.0e-19 3.1e-19 6.5e-20
5 Brain mRNA stability Cd63 0.03 0.03 5.5e-03 0 0 0 0 2.0e-01 2.6e-01 2.7e-01 3.4e-01
6 RMTg isoform ratio XM_008765025.4 0.17 0.12 1.5e-03 -0.01 0.01 -0.01 -0 8.1e-01 2.2e-01 9.5e-01 3.8e-01
7 Liver isoform ratio XM_008765025.4 0.05 0.04 2.1e-05 0.04 0.04 0.04 0.04 3.9e-05 6.3e-05 8.8e-05 5.2e-05
8 Liver alternative TSS XM_063263109.1 0.06 0.04 2.2e-06 0.04 0.04 0.03 0.03 3.2e-05 8.2e-05 2.2e-04 1.3e-04
9 Liver alternative TSS XM_008765025.4 0.06 0.05 6.1e-07 0.04 0.04 0.04 0.04 2.3e-05 3.4e-05 5.3e-05 6.0e-05
10 Liver isoform ratio NM_017125.3 0.05 0.04 1.4e-05 0.04 0.04 0.03 0.04 3.8e-05 5.4e-05 1.2e-04 4.0e-05
11 Liver gene expression Cd63 0.22 0.15 0.0e+00 0.16 0.16 0.16 0.16 2.6e-17 2.2e-17 2.9e-17 2.1e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.93.36.00.60.70.50.90.51.9-2.42.4-2.42.42.4
Area under the delay curve0.10.10.3-0.60.1-0.30.2-0.30.0-0.20.2-0.20.20.2
BMI with tail3.612.629.7-2.8-5.3-5.4-5.2-5.5-3.41.1-1.11.1-1.1-1.1
BMI without tail1.23.67.9-2.3-2.6-2.8-2.6-2.8-1.80.7-0.70.7-0.7-0.7
Body weight0.93.98.6-2.0-2.4-2.8-2.4-2.9-2.01.1-1.11.1-1.1-1.1
Weight adjusted by age0.00.10.1-0.40.1-0.30.1-0.1-0.10.3-0.30.3-0.3-0.3
Bone surface4.78.613.72.01.61.61.81.63.3-3.73.7-3.73.73.7
Bone volume4.78.413.92.21.31.41.61.33.1-3.73.7-3.73.73.7
Breakpoint value in progressive ratio session0.30.41.1-0.31.00.90.91.10.4-0.10.1-0.10.10.1
Number of licking bursts1.82.95.1-0.8-2.1-2.0-2.2-2.3-1.91.4-1.41.4-1.4-1.4
Context. condit. distance diff. score0.10.10.3-0.4-0.6-0.5-0.5-0.5-0.40.2-0.20.2-0.2-0.2
Locomotion velocity, session 11.01.12.10.70.30.30.40.21.0-1.41.4-1.41.41.4
Locomotion distance, session 11.92.43.31.51.01.11.01.11.7-1.81.8-1.81.81.8
Locomotion velocity, session 23.84.47.72.81.71.91.81.92.3-2.12.1-2.12.12.1
Locomotion distance, session 23.54.86.51.22.52.32.52.22.6-2.12.1-2.12.12.1
Locomotion velocity, session 31.82.15.70.82.42.22.22.31.3-0.20.2-0.20.20.2
Locomotion distance, session 30.10.10.4-0.60.20.20.20.2-0.10.2-0.20.2-0.2-0.2
Stereotopy head waving bouts, day 33.23.87.71.72.82.72.72.72.0-1.01.0-1.01.01.0
Stereotopy head waving duration, day 32.53.06.12.32.22.42.12.51.7-0.80.8-0.80.80.8
Locomotion velocity, session 70.30.30.40.60.40.50.40.60.6-0.60.6-0.60.60.6
Locomotion distance, session 70.50.60.9-0.8-0.6-0.5-0.7-0.5-0.90.9-0.90.9-0.9-0.9
Stereotopy head waving bouts, day 71.72.02.60.91.41.31.51.31.6-1.41.4-1.41.41.5
Stereotopy head waving duration, day 72.12.53.41.01.51.31.51.31.9-1.71.7-1.71.71.7
Locomotion velocity, session 82.83.44.70.91.81.61.91.52.2-2.02.0-2.02.02.0
Locomotion distance, session 80.40.60.9-0.61.00.70.90.70.9-0.70.7-0.70.70.7
Degree of sensitization distance0.20.20.6-0.0-0.8-0.7-0.8-0.7-0.40.0-0.00.0-0.0-0.0
Degree of sensitization stereotypy0.40.50.9-0.10.2-0.00.20.00.6-1.01.0-1.01.01.0
Conditioned locomotion2.32.63.6-1.9-1.3-1.5-1.4-1.4-1.81.7-1.71.7-1.7-1.7
Cocaine response after cond. corrected2.63.24.4-1.2-1.9-1.9-2.1-1.9-2.01.7-1.71.7-1.7-1.7
Cocaine response after cond. not corrected3.13.64.7-1.6-2.1-2.0-2.1-2.0-2.21.8-1.81.8-1.8-1.8
Cocaine response before conditioning0.40.40.90.10.70.81.00.80.6-0.60.6-0.60.60.6
Saline control response0.81.11.8-1.3-1.0-1.3-1.0-1.3-1.20.9-0.90.9-0.9-0.9
Bone: connectivity density1.11.73.10.30.50.40.60.41.4-1.81.8-1.81.81.8
Bone: cortical apparent density0.40.51.6-0.5-1.2-1.1-1.3-0.9-0.60.0-0.00.0-0.0-0.0
Bone: cortical area1.01.52.61.5-0.3-0.1-0.3-0.11.0-1.61.6-1.61.61.6
Bone: cortical porosity0.30.40.60.60.10.20.20.30.6-0.80.8-0.80.80.8
Bone: cortical porosity0.70.81.41.00.00.10.00.20.9-1.21.2-1.21.21.2
Bone: cortical thickness0.40.71.30.6-1.1-0.9-1.1-0.80.1-0.90.9-0.90.90.9
Bone: cortical thickness0.70.81.3-0.6-1.1-0.9-1.2-1.0-1.10.7-0.70.7-0.7-0.7
Bone: cortical tissue density0.30.41.1-0.5-1.0-0.9-1.1-0.8-0.50.0-0.00.0-0.0-0.0
Condit. Reinf. active minus inactive responses1.31.54.42.11.51.71.41.71.1-0.40.4-0.40.40.4
Condit. Reinf. active-inactive response ratio0.30.31.51.20.20.40.10.4-0.10.5-0.50.5-0.5-0.5
Condit. Reinf. active responses2.93.68.12.82.22.32.12.31.9-1.31.3-1.31.31.3
Condit. Reinf. inactive responses2.32.83.51.61.91.81.81.71.9-1.61.6-1.61.61.6
Incentive salience index mean1.72.14.72.21.61.71.51.61.5-1.11.1-1.11.11.1
Condit. Reinf. lever presses1.82.63.51.21.31.21.31.01.8-1.91.9-1.91.91.9
Condit. Reinf. active minus inactive responses0.71.02.00.61.21.41.21.40.20.8-0.80.8-0.8-0.8
Condit. Reinf. active-inactive response ratio1.21.32.6-0.70.10.20.10.2-1.01.6-1.61.6-1.6-1.6
Condit. Reinf. active responses0.60.92.40.81.41.61.41.50.9-0.00.0-0.00.00.0
Condit. Reinf. inactive responses0.60.71.20.80.91.00.90.91.1-0.80.8-0.80.80.8
Condit. Reinf. lever presses0.81.12.60.31.61.61.51.60.50.5-0.50.5-0.5-0.5
Condit. Reinf. lever reinforcers received0.40.61.60.41.11.31.01.20.50.3-0.30.3-0.3-0.3
Conditioned reinforcement - actives0.10.22.4-1.6-0.20.0-0.20.30.10.1-0.10.1-0.1-0.1
Conditioned reinforcement - inactives0.60.91.7-1.3-1.1-0.9-1.1-0.5-0.90.8-0.80.8-0.8-0.8
Conditioned locomotion1.51.96.20.51.51.91.52.51.6-0.80.8-0.80.80.8
Patch foraging indifference point 0 sec1.22.35.0-2.2-2.2-2.2-2.2-2.0-0.9-0.30.3-0.30.30.3
Patch foraging indifference point AUC0.30.41.11.10.90.80.80.70.30.2-0.20.2-0.2-0.2
Delay disc. indifference point, 0s delay1.21.32.4-0.7-0.4-0.8-0.3-0.90.7-1.51.5-1.51.51.5
Delay disc. indifference point, 16s delay0.30.42.21.50.40.60.70.50.4-0.30.3-0.30.30.3
Delay disc. indifference point, 2s delay0.30.40.7-0.2-0.0-0.30.0-0.50.3-0.80.8-0.80.80.8
Delay disc. indifference point, 24s delay0.40.53.9-2.0-0.5-0.8-0.2-0.7-0.30.0-0.00.0-0.0-0.0
Delay disc. indifference point, 4s delay0.80.91.2-0.10.90.71.00.61.1-1.11.1-1.11.11.1
Delay disc. indifference point, 8s delay0.60.62.2-1.5-0.3-0.8-0.3-0.8-0.80.8-0.80.8-0.8-0.8
Indifference point function ln k0.00.10.20.3-0.3-0.0-0.4-0.1-0.20.1-0.10.1-0.1-0.1
Indifference point function log k0.00.10.20.3-0.3-0.0-0.4-0.1-0.20.1-0.10.1-0.1-0.1
Patch foraging total patch changes 0 sec1.02.04.5-2.0-2.1-2.0-2.1-1.9-0.9-0.30.3-0.30.30.3
Patch foraging total patch changes 12 sec1.41.93.6-1.7-1.7-1.9-1.7-1.8-1.30.8-0.80.8-0.8-0.8
Patch foraging total patch changes 18 sec0.10.21.5-1.2-0.1-0.50.1-0.30.0-0.30.3-0.30.30.3
Patch foraging total patch changes 24 sec0.20.41.6-1.3-0.6-0.8-0.4-0.7-0.0-0.50.5-0.50.50.5
Patch foraging total patch changes 6 sec0.50.82.50.7-1.6-1.3-1.6-1.3-0.5-0.10.1-0.10.10.1
Patch foraging time to switch 0 sec0.20.40.6-0.6-0.3-0.4-0.2-0.40.5-0.80.8-0.80.80.8
Patch foraging water rate 0 sec0.71.42.0-1.4-1.2-1.1-1.3-1.1-1.41.2-1.21.2-1.2-1.2
Patch foraging water rate 12 sec0.81.62.4-1.0-1.4-1.1-1.4-1.2-1.51.2-1.21.2-1.2-1.2
Patch foraging water rate 18 sec2.03.25.4-0.4-0.9-0.8-1.0-0.9-2.12.3-2.32.3-2.3-2.3
Patch foraging water rate 24 sec4.76.69.6-1.8-2.2-2.1-2.3-2.3-3.12.8-2.82.8-2.8-2.8
Patch foraging water rate 6 sec0.81.12.2-0.3-0.10.2-0.10.3-1.11.5-1.51.5-1.5-1.5
Seeking ratio, delayed vs. immediate footshock1.31.62.91.11.41.61.41.71.4-1.01.0-1.01.01.0
Distance traveled before self-admin0.81.02.61.61.41.41.41.30.8-0.40.4-0.40.40.4
Distance traveled after self-admin0.30.44.5-2.10.2-0.20.1-0.2-0.00.0-0.00.0-0.0-0.0
Extensor digitorum longus weight3.413.525.0-3.4-5.0-4.9-5.0-5.0-3.92.2-2.22.2-2.2-2.2
Bone: elastic displacement0.10.10.7-0.8-0.1-0.1-0.10.00.1-0.10.1-0.10.10.1
Bone: elastic work0.30.40.6-0.6-0.7-0.8-0.7-0.80.0-0.60.6-0.60.60.6
Bone: endosteal estimation0.20.40.60.3-0.6-0.5-0.6-0.50.3-0.80.8-0.80.80.8
Bone: endosteal perimeter0.81.82.41.31.21.21.21.31.5-1.41.4-1.41.41.4
Epididymis fat weight0.20.81.5-0.5-0.1-0.2-0.1-0.2-0.81.2-1.21.2-1.2-1.2
Delta time in closed arm before/after self-admin4.34.05.2-1.4-2.0-1.6-1.9-1.7-2.32.2-2.22.2-2.2-2.2
Delta time in open arm before/after self-admin0.90.95.3-2.3-0.7-1.2-0.7-1.1-0.70.2-0.20.2-0.2-0.2
Diff in mean of infusions in LGA sessions0.70.82.40.21.31.51.41.50.8-0.00.0-0.00.00.0
Delay discount exponential model param0.10.10.30.6-0.20.2-0.30.2-0.00.2-0.20.2-0.2-0.2
Extinction: sum of active levers before priming0.50.61.1-0.00.80.90.81.1-0.00.8-0.80.8-0.8-0.8
Active lever presses in extinction session 60.30.30.50.60.60.50.50.70.5-0.50.5-0.50.50.5
Bone: final force0.91.41.9-0.2-1.3-1.3-1.2-1.20.3-1.41.4-1.41.41.4
Bone: final moment0.91.41.9-0.4-1.3-1.3-1.2-1.20.3-1.41.4-1.41.41.4
Food consumed during 24 hour testing period0.10.20.5-0.1-0.7-0.6-0.7-0.7-0.40.1-0.10.1-0.1-0.1
Glucose1.11.76.2-2.5-1.4-1.8-1.4-1.8-1.10.4-0.40.4-0.4-0.4
Heart weight0.20.30.50.00.20.20.20.3-0.30.7-0.70.7-0.7-0.7
Delay discount hyperbolic model param0.10.10.40.6-0.00.3-0.10.4-0.10.4-0.40.4-0.4-0.4
Intermittent access intake day 1-15 change0.10.30.4-0.40.30.40.20.6-0.20.7-0.70.7-0.7-0.7
Intermittent access intake escalation0.20.30.7-0.90.20.30.20.5-0.30.7-0.70.7-0.7-0.7
Intermittent access intake escalation 20.20.20.5-0.40.70.60.60.70.10.3-0.30.3-0.3-0.3
Intermitt. access day 1 inactive lever presses0.31.22.4-0.6-0.1-0.0-0.20.1-1.01.5-1.51.5-1.5-1.5
Intermitt. access day 15 inactive lever presses0.10.30.8-0.40.80.90.90.70.20.2-0.20.2-0.2-0.2
Intermitt. access escalation Index0.30.50.8-0.60.30.10.20.30.8-0.90.9-0.90.90.9
Intermittent access day 1 total infusions0.40.75.6-2.4-0.7-0.5-0.7-0.3-0.30.4-0.40.4-0.4-0.4
Intermittent access day 15 total infusions0.10.22.2-1.5-0.20.1-0.20.40.2-0.00.0-0.00.00.0
Intermittent access terminal intake (last 3 days)0.40.63.1-1.80.30.50.30.70.7-0.60.6-0.60.60.6
Intermittent access total infusions0.40.55.3-2.3-0.4-0.2-0.30.10.1-0.10.1-0.10.10.1
Intermittent access day 1 locomotion1.01.37.5-2.7-0.7-0.6-0.7-0.3-0.71.0-1.01.0-1.0-1.0
Intermittent access day 15 total locomotion0.20.42.0-1.40.00.1-0.00.7-0.20.5-0.50.5-0.5-0.5
Intermittent access total locomotion0.50.65.7-2.40.0-0.10.00.4-0.10.4-0.40.4-0.4-0.4
Intermittent access standard deviation0.40.92.31.00.91.30.91.51.1-0.60.6-0.60.60.6
Left kidney weight0.00.10.2-0.1-0.1-0.2-0.2-0.3-0.40.5-0.50.5-0.5-0.5
Right kidney weight0.10.30.50.60.50.40.50.4-0.10.7-0.70.7-0.7-0.7
Cocaine induced anxiety2.23.15.42.31.81.71.91.81.9-1.61.6-1.61.61.6
Post-drug Anxiety3.23.44.61.41.51.21.61.52.0-2.22.2-2.22.22.2
Baseline Anxiety0.10.10.5-0.7-0.1-0.1-0.1-0.2-0.1-0.10.1-0.10.10.1
Tail length1.14.512.01.33.53.33.33.31.70.0-0.00.0-0.0-0.0
Length with tail0.41.74.20.92.01.92.01.80.60.6-0.60.6-0.6-0.6
Length without tail0.30.91.3-0.2-1.1-1.1-1.0-1.2-1.00.8-0.80.8-0.8-0.8
Times rat made contact with spout1.21.32.3-1.1-1.4-1.4-1.3-1.5-1.30.9-0.90.9-0.9-0.9
Lifetime Intake0.70.97.7-2.8-0.8-0.6-0.8-0.3-0.0-0.30.3-0.30.30.3
Liver weight, left0.20.40.80.1-0.9-0.8-0.9-0.9-0.60.4-0.40.4-0.4-0.4
Liver weight, right0.10.20.4-0.20.2-0.20.2-0.2-0.30.6-0.60.6-0.6-0.6
Locomotor activity2.64.16.92.62.52.32.62.42.0-1.41.4-1.41.41.4
Locomotor testing distance1.42.56.12.51.71.71.91.81.6-1.11.1-1.11.11.1
Locomotor testing rearing0.10.10.2-0.3-0.1-0.3-0.0-0.2-0.30.4-0.40.4-0.4-0.4
Locomotion in novel chamber0.00.00.20.4-0.4-0.1-0.3-0.0-0.0-0.00.0-0.00.00.0
Locomotion in novel chamber post-restriction1.82.96.32.52.52.52.42.31.3-0.40.4-0.40.40.4
Fecal boli incidents, locomotor time 10.81.21.9-0.4-1.2-1.2-1.0-1.3-1.41.0-1.01.0-1.0-1.0
Change in fecal boli incidents, locomotor task1.91.92.51.51.21.21.01.11.6-1.51.5-1.51.51.5
Time >=10cm from walls, locomotor time 10.60.71.40.1-0.3-0.3-0.0-0.20.7-1.21.2-1.21.21.2
Bouts of movement, locomotor time 10.50.52.71.60.80.80.90.70.30.2-0.20.2-0.2-0.2
Total resting periods, locomotor time 10.70.82.01.41.21.21.41.20.6-0.00.0-0.00.00.0
Rest time, locomotor task time 10.50.61.30.21.00.81.10.80.9-0.70.7-0.70.70.7
Distance moved, locomotor task time 10.50.81.50.1-0.5-0.4-0.6-0.30.6-1.21.2-1.21.21.2
Vertical activity count, locomotor time 10.30.72.2-0.1-1.4-1.1-1.5-0.9-0.70.3-0.30.3-0.3-0.3
Time >=10cm from walls, locomotor time 20.81.11.9-1.4-1.2-1.3-1.2-1.2-1.10.8-0.80.8-0.8-0.8
Bouts of movement, locomotor time 20.91.44.82.20.70.91.00.71.1-1.11.1-1.11.11.1
Total resting periods, locomotor time 20.91.64.32.10.80.91.10.81.3-1.31.3-1.31.31.3
Rest time, locomotor task time 20.50.70.90.40.70.40.70.50.9-1.01.0-1.01.01.0
Distance moved, locomotor task time 20.50.61.2-1.1-0.5-0.5-0.6-0.3-0.70.9-0.90.9-0.9-0.9
Vertical activity count, locomotor time 21.72.33.1-1.6-1.8-1.6-1.6-1.4-1.71.4-1.41.4-1.4-1.4
Light reinforcement 11.53.67.80.82.72.62.72.81.9-1.21.2-1.21.21.2
Light reinforcement 20.50.71.5-0.21.21.21.21.20.8-0.50.5-0.50.50.5
Bone: marrow area0.20.30.50.3-0.6-0.5-0.5-0.40.2-0.70.7-0.70.70.7
Bone: maximum diameter1.52.84.32.11.31.51.41.61.9-1.71.7-1.71.71.7
Bone: maximum force0.81.32.1-0.5-1.4-1.5-1.4-1.40.0-1.11.1-1.11.11.1
Bone: maximum moment0.81.42.3-0.6-1.5-1.5-1.4-1.40.0-1.11.1-1.11.11.1
Mean time between licks in bursts0.20.51.41.11.01.10.71.20.50.3-0.30.3-0.3-0.3
Mean num. licks in bursts0.30.51.1-0.40.80.71.00.90.8-0.60.6-0.60.60.6
Cd content in liver0.30.31.81.30.50.70.50.80.5-0.10.1-0.10.10.1
Co content in liver0.91.02.21.21.51.51.41.50.50.4-0.40.4-0.4-0.4
Cu content in liver0.91.01.91.4-0.2-0.0-0.10.20.8-1.31.3-1.31.31.3
Fe content in liver0.20.30.5-0.5-0.7-0.5-0.7-0.4-0.60.5-0.50.5-0.5-0.5
K content in liver1.21.11.61.11.11.01.21.11.3-1.01.0-1.01.01.0
Mg content in liver1.21.22.61.61.31.31.31.11.2-0.80.8-0.80.80.8
Mn content in liver5.46.07.72.82.02.02.12.02.7-2.62.6-2.62.62.6
Na content in liver0.60.72.9-1.70.2-0.50.2-0.20.4-0.90.9-0.90.90.9
Rb content in liver1.21.44.62.2-0.10.20.00.31.1-1.41.4-1.41.41.4
Se content in liver0.00.00.40.70.20.20.10.10.10.0-0.00.0-0.0-0.0
Sr content in liver0.40.30.9-1.00.1-0.00.00.3-0.30.7-0.70.7-0.7-0.7
Zn content in liver1.51.72.51.01.11.21.01.1-0.51.6-1.61.6-1.6-1.6
Bone: minimum diameter0.50.91.91.4-0.00.30.00.20.9-1.21.2-1.21.21.2
Time in familiar zone, hab. session 11.41.33.60.31.91.81.91.80.70.3-0.30.3-0.3-0.3
Time in novel zone, hab. session 11.21.21.8-0.4-1.3-1.3-1.3-1.20.1-1.11.1-1.11.11.1
Total zone transitions, hab. session 11.52.12.70.91.31.11.21.01.6-1.71.7-1.71.71.7
Total locomotion distance, hab. session 13.85.37.41.02.22.02.32.02.7-2.52.5-2.52.52.5
Locomotion velocity, hab. session 12.94.15.71.12.21.92.21.92.4-2.12.1-2.12.12.1
Time in familiar zone, hab. session 21.51.63.70.91.81.91.71.90.40.8-0.80.8-0.8-0.8
Time in novel zone, hab. session 21.71.83.6-0.8-1.8-1.9-1.7-1.9-0.2-1.01.0-1.01.01.0
Total zone transitions, hab. session 21.41.83.70.30.0-0.00.00.01.2-1.91.9-1.91.91.9
Total locomotion distance, hab. session 21.11.52.1-0.21.10.91.10.91.4-1.41.4-1.41.41.4
Locomotion velocity, hab. session 21.72.23.20.01.31.01.31.01.7-1.81.8-1.81.81.8
Novel to familiar place preference ratio1.21.31.8-0.4-1.1-1.3-1.0-1.30.3-1.31.3-1.31.31.3
Novelty place preference1.01.01.6-0.3-0.8-1.0-0.7-0.90.4-1.31.3-1.31.31.3
Time in novel zone, NPP test1.01.11.5-0.4-1.1-1.2-1.0-1.10.2-1.21.2-1.21.21.2
Total zone transitions, NPP test0.40.61.1-0.5-0.1-0.4-0.2-0.50.5-1.01.0-1.01.01.0
Total locomotion distance, NPP test0.81.11.9-0.90.50.00.40.01.0-1.41.4-1.41.41.4
Locomotion velocity, NPP test0.81.11.8-0.70.80.30.70.31.1-1.31.3-1.31.31.3
Intraocular pressure0.81.12.0-0.40.0-0.2-0.0-0.4-1.11.4-1.41.4-1.4-1.4
Delta distance traveled before/after self-admin1.01.06.6-2.6-0.8-1.1-0.9-1.0-0.60.4-0.40.4-0.4-0.4
Delta ambulatory time before/after self-admin0.40.53.3-1.8-0.6-0.8-0.7-0.7-0.1-0.10.1-0.10.10.1
Parametrial fat weight0.10.30.8-0.6-0.8-0.9-0.8-0.9-0.2-0.30.3-0.30.30.3
Pavlov. Cond. lever latency1.41.72.5-1.4-0.9-0.8-0.8-0.7-1.41.6-1.61.6-1.6-1.6
Pavlov. Cond. magazine entry latency0.81.02.31.51.41.51.31.40.8-0.20.2-0.20.20.2
Pavlov. Cond. change in total contacts0.10.10.90.9-0.3-0.0-0.3-0.1-0.1-0.20.2-0.20.20.2
Pavlov. Cond. index score0.81.12.21.51.01.11.01.01.0-0.90.9-0.90.90.9
Pavlov. Cond. latency score1.31.72.81.71.21.31.21.21.4-1.31.3-1.31.31.3
Pavlov. Cond. lever contacts1.11.32.01.10.60.60.60.41.2-1.41.4-1.41.41.4
Pavlov. Cond. magazine entry number0.40.51.9-1.4-0.9-1.0-0.8-0.8-0.4-0.00.0-0.00.00.0
Pavlov. Cond. intertrial magazine entries0.40.51.0-0.4-0.1-0.2-0.2-0.1-0.71.0-1.01.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.02.11.51.11.21.01.11.0-0.80.8-0.80.80.8
Pavlov. Cond. response bias0.40.41.41.20.90.90.80.80.5-0.20.2-0.20.20.2
Pavlov. Cond. lever latency0.60.92.4-0.6-1.6-1.4-1.5-1.3-0.90.2-0.20.2-0.2-0.2
Pavlov. Cond. magazine entry latency1.21.43.11.61.81.71.71.51.1-0.40.4-0.40.40.4
Pavlov. Cond. change in total contacts0.30.51.41.20.91.10.90.90.40.1-0.10.1-0.1-0.1
Pavlov. Cond. index score0.91.22.71.51.61.71.51.50.9-0.10.1-0.10.10.1
Pavlov. Cond. latency score1.11.53.21.61.81.81.71.61.1-0.40.4-0.40.40.4
Pavlov. Cond. lever contacts0.50.71.90.81.41.31.31.20.60.1-0.10.1-0.1-0.1
Pavlov. Cond. magazine entry number1.51.84.4-2.1-1.8-1.9-1.7-1.7-1.20.5-0.50.5-0.5-0.5
Pavlov. Cond. intertrial magazine entries1.01.53.6-1.9-1.4-1.6-1.3-1.4-1.10.8-0.80.8-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.1.11.53.41.71.71.81.71.71.1-0.30.3-0.30.30.3
Pavlov. Cond. response bias0.81.12.71.11.61.61.61.50.70.2-0.20.2-0.2-0.2
Time in closed arm before self-admin0.50.71.20.60.20.20.20.20.8-1.11.1-1.11.11.1
Time in closed arm after self-admin0.20.30.80.4-0.8-0.5-0.9-0.4-0.50.3-0.30.3-0.3-0.3
Time in open arm before self-admin0.10.10.80.9-0.10.2-0.10.20.00.1-0.10.1-0.1-0.1
Time in open arm after self-admin1.82.08.4-2.9-1.3-1.7-1.4-1.7-1.20.7-0.70.7-0.7-0.7
Bone: periosteal estimation0.71.62.81.4-0.5-0.2-0.4-0.20.9-1.71.7-1.71.71.7
Bone: periosteal perimeter1.22.14.02.00.60.80.70.81.5-1.71.7-1.71.71.7
Bone: post-yield work0.20.20.8-0.5-0.7-0.9-0.7-0.9-0.3-0.00.0-0.00.00.0
Progressive ratio test 1 active lever presses1.01.210.0-3.2-0.8-1.0-0.8-0.6-0.40.4-0.40.4-0.4-0.4
Progressive ratio test 1 breakpoint1.11.310.2-3.2-0.9-1.0-0.9-0.6-0.40.4-0.40.4-0.4-0.4
Progressive ratio test 1 inactive lever presses0.10.21.3-1.10.30.50.30.70.3-0.00.0-0.00.00.0
Progressive ratio test 2 active lever presses0.40.54.9-2.20.10.10.10.40.2-0.10.1-0.10.10.1
Progressive ratio test 2 breakpoint0.50.55.3-2.30.20.20.30.50.3-0.10.1-0.10.10.1
Progressive ratio test 2 inactive lever presses0.71.19.7-3.1-0.2-0.2-0.10.10.5-0.60.6-0.60.60.6
Incentive Sensitization - Responses0.20.21.3-1.10.50.60.60.60.30.0-0.00.0-0.0-0.0
Incentive Sensitization - Breakpoint0.20.30.7-0.80.70.80.80.80.5-0.20.2-0.20.20.2
Sum of active levers in priming session hrs 5-60.10.10.1-0.30.30.30.30.4-0.00.1-0.10.1-0.1-0.1
Progressive ratio0.81.22.5-0.8-1.5-1.4-1.6-1.3-1.20.8-0.80.8-0.8-0.8
Food seeking constrained by brief footshock0.70.82.51.01.61.41.51.10.60.0-0.00.0-0.0-0.0
Seeking ratio, punishment vs. effort1.01.54.11.12.01.82.01.51.1-0.40.4-0.40.40.4
Retroperitoneal fat weight1.98.213.8-3.2-3.5-3.7-3.5-3.6-3.12.0-2.02.0-2.0-2.0
Reaction time number correct1.02.03.0-1.7-1.4-1.3-1.4-1.6-1.61.3-1.31.3-1.3-1.3
Reaction time mean minus median0.51.23.61.91.31.51.31.31.0-0.40.4-0.40.40.4
Reaction time mean minus median AUC1.33.34.32.01.91.91.91.82.1-1.71.7-1.71.71.7
Reaction time num false alarms0.40.61.5-0.7-1.0-1.2-1.1-1.1-0.70.4-0.40.4-0.4-0.4
Reaction time num false alarms AUC0.61.01.9-1.0-1.1-1.4-1.2-1.3-1.00.7-0.70.7-0.7-0.7
Reaction time trials correct on left1.02.03.0-1.7-1.4-1.3-1.4-1.6-1.61.3-1.31.3-1.3-1.3
Reaction time trials on left1.01.82.7-1.7-1.4-1.3-1.4-1.5-1.51.2-1.21.2-1.2-1.2
Reaction time mean1.42.23.51.91.61.81.71.61.6-1.21.2-1.21.21.2
Reaction time mean AUC1.01.52.41.51.21.41.21.21.4-1.11.1-1.11.11.1
Median of all reaction times1.21.72.31.51.31.41.31.31.5-1.21.2-1.21.21.2
Reaction time omissions0.40.51.01.00.40.60.30.50.8-0.80.8-0.80.80.8
Reaction time false alarm rate0.10.10.4-0.2-0.3-0.6-0.4-0.4-0.0-0.20.2-0.20.20.2
Reaction time premature initiation rate0.50.71.1-1.10.90.50.90.7-0.20.9-0.90.9-0.9-0.9
Reaction time premature initiations0.91.63.5-1.90.2-0.20.1-0.1-1.11.6-1.61.6-1.6-1.6
Std. dev. reaction times0.71.42.91.71.31.41.31.21.3-0.90.9-0.90.90.9
Reaction time trials completed1.01.82.7-1.7-1.4-1.3-1.4-1.5-1.51.2-1.21.2-1.2-1.2
Reaction time trials AUC1.32.43.6-1.9-1.5-1.4-1.6-1.7-1.81.4-1.41.4-1.4-1.4
Run reversals in cocaine runway, females2.22.23.90.92.01.92.01.91.7-1.01.1-1.11.11.1
Run reversals in cocaine runway, males2.42.44.01.61.92.01.92.01.6-1.21.2-1.21.21.2
Latency to leave start box in cocaine runway0.91.12.10.60.60.00.30.11.2-1.51.3-1.31.31.4
Latency to leave start box in cocaine runway, F1.71.93.90.60.80.20.40.21.5-2.01.8-1.81.81.8
Latency to leave start box in cocaine runway, M0.20.20.3-0.2-0.3-0.3-0.3-0.4-0.40.5-0.50.5-0.5-0.5
Std. dev. time between licks in bursts1.31.72.71.41.21.41.21.41.6-1.21.2-1.21.21.2
Total sessions with >9 infusions0.40.42.9-1.7-0.8-0.4-0.7-0.00.1-0.30.3-0.30.30.3
Short access day 1 total inactive lever presses0.20.20.4-0.60.30.40.30.5-0.10.5-0.50.5-0.5-0.5
Short access day 10 total inactive lever presses0.51.32.50.3-0.5-0.1-0.5-0.2-1.21.6-1.61.6-1.6-1.6
Short access day 1 total infusions0.20.31.7-1.3-0.8-0.3-0.70.00.1-0.30.3-0.30.30.3
Short access day 10 total infusions0.40.54.5-2.1-0.6-0.3-0.6-0.1-0.10.2-0.20.2-0.2-0.2
Short access total infusions0.81.08.1-2.8-0.9-0.6-0.9-0.30.0-0.40.4-0.40.40.4
Short access day 1 locomotion0.20.20.8-0.90.20.50.20.90.30.4-0.40.4-0.4-0.4
Short access day 10 total locomotion0.61.11.7-1.10.70.80.51.3-0.21.3-1.31.3-1.3-1.3
Short access total locomotion0.40.42.8-1.70.10.20.10.80.00.5-0.50.5-0.5-0.5
One hour access (0.3 mA shock)0.20.30.8-0.9-0.5-0.5-0.5-0.5-0.60.4-0.40.4-0.4-0.4
Compulsive drug intake0.10.20.91.00.30.20.30.00.2-0.40.4-0.40.40.4
One hour access (shock baseline)0.20.43.4-1.9-0.10.0-0.10.3-0.10.3-0.30.3-0.3-0.3
Social response proportion0.70.81.80.21.31.01.41.00.9-0.60.6-0.60.60.6
Social responses5.06.514.31.23.83.43.83.62.8-1.41.4-1.41.41.4
Social time0.81.12.0-0.4-1.4-1.3-1.4-1.4-1.20.7-0.70.7-0.7-0.7
Soleus weight2.77.918.0-3.0-4.2-4.2-4.0-4.2-2.60.7-0.70.7-0.7-0.7
Bone: stiffness1.01.63.8-0.8-1.9-1.9-1.9-1.8-0.4-0.70.7-0.70.70.7
Tibialis anterior weight0.61.94.7-0.9-2.2-2.1-2.1-2.1-1.40.4-0.40.4-0.4-0.4
Time to tail flick, vehicle, before self-admin1.92.05.32.31.41.41.31.51.3-1.21.2-1.21.21.2
Time to tail flick, vehicle, after self-admin0.70.91.70.60.30.30.0-0.1-0.81.3-1.31.3-1.3-1.3
Time to tail flick, test, before self-admin2.12.16.12.51.11.31.21.31.6-1.31.3-1.31.31.3
Time to tail flick, test, after self-admin0.20.20.4-0.10.20.20.20.20.5-0.60.6-0.60.60.6
Delta time to tail flick, vehicle, before/after SA2.82.73.5-1.3-1.3-1.5-1.5-1.8-1.91.7-1.71.7-1.7-1.7
Delta time to tail flick, test, before/after SA1.31.34.2-2.0-0.5-0.6-0.5-0.7-1.21.2-1.21.2-1.2-1.2
Tibia length0.20.62.1-0.41.41.11.41.00.50.3-0.30.3-0.3-0.3
Ambulatory time before self-admin0.10.20.50.70.70.60.70.60.3-0.10.1-0.10.10.1
Ambulatory time after self-admin0.30.44.2-2.10.1-0.30.1-0.20.0-0.10.1-0.10.10.1
Bone: tissue strength1.81.84.5-1.7-2.0-2.1-2.0-1.9-0.8-0.30.3-0.30.30.3
Total heroin consumption1.31.53.50.11.91.61.81.61.3-0.80.8-0.80.80.8
Bone: trabecular number1.32.23.00.71.41.11.41.01.7-1.71.7-1.71.71.7
Bone: trabecular spacing3.03.96.1-1.3-1.4-1.2-1.4-1.0-2.22.5-2.52.5-2.5-2.5
Bone: trabecular thickness5.26.511.22.01.01.11.20.92.7-3.33.3-3.33.33.3
Bone: trabecular tissue density2.84.18.2-1.5-2.8-2.7-2.9-2.7-2.11.2-1.21.2-1.2-1.2
Water consumed over 24 hours0.30.50.70.4-0.6-0.6-0.5-0.70.3-0.80.8-0.80.80.8
Number of responses in last shaping day0.60.72.5-0.80.91.30.91.60.50.5-0.50.5-0.5-0.5