Hub : Genes

Ccdc47

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Ccdc47 0.04 0.02 1.1e-05 0.04 0.04 0.04 0.04 6.2e-05 3.2e-05 4.1e-05 4.4e-05
2 PL gene expression Ccdc47 0.08 0.04 5.0e-07 0.03 0.05 0.05 0.05 7.1e-04 2.0e-06 2.3e-06 1.2e-06
3 Adipose alternative TSS XM_039086169.1 0.04 0.02 4.1e-04 0.01 0.02 0.02 0.01 3.4e-02 3.0e-03 6.1e-03 2.0e-02
4 Adipose isoform ratio NM_001013974.1 0.05 0.03 1.7e-04 0.03 0.03 0.03 0.02 6.4e-04 2.2e-04 1.1e-04 9.2e-04
5 Adipose alternative TSS NM_001013974.1 0.04 0.02 8.2e-04 0.01 0.02 0.01 0.01 5.0e-02 5.5e-03 1.4e-02 3.2e-02
6 Brain gene expression Ccdc47 0.12 0.06 3.2e-08 0.08 0.08 0.08 0.07 4.2e-08 3.2e-08 1.2e-07 2.2e-07
7 Adipose isoform ratio XM_039086169.1 0.05 0.03 2.3e-04 0.02 0.03 0.03 0.02 5.1e-03 3.4e-04 2.5e-04 3.3e-03
8 Liver alternative TSS XM_039086169.1 0.12 0.06 4.7e-03 0 -0 -0 -0 3.4e-01 4.2e-01 7.4e-01 4.1e-01
9 Liver mRNA stability Ccdc47 0.05 0.03 5.9e-04 0.01 0.01 0.01 0.01 1.6e-02 7.8e-03 9.2e-03 5.3e-02
10 BLA gene expression Ccdc47 0.07 0.04 2.0e-03 0.03 0.02 0.02 0.03 7.9e-03 2.5e-02 2.8e-02 1.4e-02
11 Eye alternative TSS XM_039086169.1 0.57 0.17 8.8e-03 -0.02 -0.02 -0.02 -0.02 1.0e+00 8.9e-01 9.5e-01 7.8e-01
12 Brain mRNA stability Ccdc47 0.21 0.07 3.6e-11 0.14 0.13 0.13 0.14 1.0e-12 4.6e-12 9.9e-12 8.8e-13
13 Liver gene expression Ccdc47 0.16 0.06 1.6e-08 0.08 0.07 0.07 0.07 5.2e-09 2.7e-08 1.5e-08 1.1e-08
14 Adipose mRNA stability Ccdc47 0.13 0.05 5.0e-11 0.08 0.07 0.08 0.07 1.9e-09 1.4e-08 7.5e-09 2.7e-08
15 Adipose gene expression Ccdc47 0.1 0.04 5.6e-10 0.06 0.07 0.06 0.06 5.4e-07 2.4e-08 7.0e-07 2.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density4.57.611.62.42.3-3.2-3.33.32.83.40.72.60.93.33.4-3.1-3.01.7
Area under the delay curve0.40.41.40.50.8-0.7-0.70.61.20.8-0.20.4-0.4-0.00.6-0.7-0.7-0.0
BMI with tail0.82.710.3-0.9-1.31.3-0.0-1.41.5-0.53.2-1.0-2.9-1.9-1.11.11.0-2.3
BMI without tail1.43.014.00.60.5-0.0-1.0-0.12.80.63.7-0.5-3.2-1.1-0.71.01.0-2.7
Body weight1.35.314.32.52.3-1.9-3.11.83.52.53.81.4-3.70.40.00.50.5-1.7
Weight adjusted by age1.01.13.6-0.8-0.71.01.8-1.1-0.6-1.9-0.3-0.6-0.6-1.8-1.10.70.7-0.4
Bone surface8.815.627.04.64.5-5.2-4.75.23.74.50.84.5-1.44.03.8-3.5-3.32.3
Bone volume7.512.721.44.04.0-4.6-4.34.63.74.21.03.8-0.93.53.5-3.3-3.11.8
Breakpoint value in progressive ratio session0.40.51.40.90.9-0.50.60.5-0.1-0.70.80.40.3-0.5-0.91.20.8-0.1
Number of licking bursts0.10.10.60.30.4-0.3-0.00.3-0.10.1-0.20.8-0.40.20.0-0.2-0.00.7
Context. condit. distance diff. score1.11.32.6-0.9-0.91.30.9-1.3-0.9-1.01.4-0.8-0.4-1.3-1.61.51.6-0.7
Locomotion velocity, session 12.42.65.91.51.5-1.9-2.31.91.52.40.41.50.02.01.7-1.3-1.40.8
Locomotion distance, session 10.81.02.50.40.8-0.8-1.30.71.21.61.10.80.51.31.2-1.0-0.90.3
Locomotion velocity, session 20.50.61.31.01.0-1.0-0.31.1-0.40.50.51.10.61.10.5-0.6-0.51.0
Locomotion distance, session 20.30.41.90.20.6-0.2-0.50.2-0.20.81.40.70.91.00.1-0.00.30.7
Locomotion velocity, session 30.30.41.6-0.3-0.3-0.1-0.10.10.20.21.30.90.50.60.5-0.8-0.61.1
Locomotion distance, session 30.50.51.80.50.6-0.8-0.40.80.20.50.11.30.00.70.6-0.9-0.71.3
Stereotopy head waving bouts, day 30.40.51.5-0.3-0.3-0.2-0.50.20.50.7-0.20.11.20.91.2-1.0-1.10.5
Stereotopy head waving duration, day 30.10.10.6-0.6-0.40.40.1-0.40.20.00.2-0.20.70.00.10.1-0.10.0
Locomotion velocity, session 70.20.21.1-0.6-0.80.4-0.2-0.3-0.40.3-0.4-0.21.00.60.4-0.4-0.30.4
Locomotion distance, session 70.30.41.0-0.4-0.00.60.9-0.7-0.3-0.80.2-0.60.4-1.0-0.70.40.7-0.7
Stereotopy head waving bouts, day 70.50.61.9-0.3-0.2-0.1-0.10.2-0.10.51.20.71.40.90.8-0.8-0.81.2
Stereotopy head waving duration, day 70.80.95.4-1.0-0.90.60.4-0.5-1.4-0.10.10.32.31.00.3-0.1-0.21.7
Locomotion velocity, session 80.50.62.10.50.2-0.1-1.00.1-0.50.70.10.2-1.40.4-1.01.21.4-0.2
Locomotion distance, session 80.60.82.9-0.4-0.10.80.5-0.9-0.7-0.41.6-0.40.4-0.5-1.41.41.7-0.5
Degree of sensitization distance0.80.83.1-0.20.00.70.4-0.8-0.1-0.40.1-1.4-0.3-1.0-1.01.31.3-1.8
Degree of sensitization stereotypy0.70.72.6-0.8-0.80.50.4-0.4-1.1-0.01.60.61.40.70.2-0.3-0.31.5
Conditioned locomotion0.50.62.30.30.50.30.6-0.30.1-0.7-0.2-1.10.0-0.9-0.91.00.9-1.5
Cocaine response after cond. corrected0.60.61.90.10.1-0.5-0.10.50.20.1-1.31.0-1.10.20.8-1.4-1.01.1
Cocaine response after cond. not corrected1.61.86.30.40.3-1.1-0.51.1-0.10.5-1.02.1-0.61.31.5-2.2-1.82.5
Cocaine response before conditioning0.91.13.70.30.3-0.8-0.50.9-0.20.61.11.51.21.61.1-1.1-1.11.9
Saline control response1.21.64.50.50.40.40.8-0.50.1-1.12.1-1.1-0.9-1.7-1.51.71.4-2.1
Bone: connectivity density4.67.311.42.72.8-3.3-3.13.42.53.30.62.70.83.13.0-2.8-2.71.7
Bone: cortical apparent density2.12.810.1-2.8-2.42.31.6-2.3-0.6-1.20.3-1.83.2-0.6-0.00.10.1-0.2
Bone: cortical area4.06.112.02.22.1-2.7-2.62.73.52.43.02.8-1.41.92.5-2.6-2.41.1
Bone: cortical porosity9.210.019.24.13.1-4.3-3.14.42.22.51.44.2-3.72.62.5-2.8-2.72.2
Bone: cortical porosity7.48.115.53.32.6-3.6-2.83.72.32.21.93.9-3.42.32.3-2.6-2.52.1
Bone: cortical thickness2.03.38.7-1.8-1.90.4-0.2-0.31.60.62.61.01.71.32.6-2.9-2.81.8
Bone: cortical thickness1.82.15.4-1.5-1.60.50.5-0.40.2-0.11.90.82.00.91.9-2.3-2.21.9
Bone: cortical tissue density2.22.910.1-2.8-2.52.31.6-2.3-0.7-1.20.2-1.93.2-0.7-0.10.20.2-0.3
Condit. Reinf. active minus inactive responses1.11.23.61.81.8-1.5-0.71.51.10.61.91.0-0.90.10.3-0.2-0.4-0.2
Condit. Reinf. active-inactive response ratio0.50.62.31.21.1-0.9-0.51.00.40.51.50.8-0.40.20.2-0.1-0.20.1
Condit. Reinf. active responses1.21.44.62.12.1-1.6-0.91.51.30.81.70.8-0.80.10.00.10.0-0.6
Condit. Reinf. inactive responses0.60.72.31.21.5-1.0-1.01.01.31.00.20.4-0.10.50.20.00.1-0.5
Incentive salience index mean1.72.04.42.11.9-2.0-1.52.01.21.41.51.6-0.41.20.9-0.7-0.90.5
Condit. Reinf. lever presses0.50.72.00.90.7-1.0-1.11.10.21.10.40.80.71.40.6-0.5-0.30.7
Condit. Reinf. active minus inactive responses6.17.516.03.64.0-3.7-2.73.62.82.52.93.6-0.92.01.8-1.7-1.61.4
Condit. Reinf. active-inactive response ratio4.64.89.32.82.9-3.0-2.23.01.82.21.02.7-0.62.01.7-1.8-1.61.4
Condit. Reinf. active responses3.75.114.43.43.8-3.0-1.83.02.71.63.02.4-1.10.70.9-0.8-0.90.1
Condit. Reinf. inactive responses0.91.26.71.11.5-0.40.30.31.3-0.32.6-0.2-0.2-1.2-0.70.80.5-1.6
Condit. Reinf. lever presses1.21.66.41.61.6-1.5-0.91.51.20.82.51.4-0.60.80.7-0.6-0.60.3
Condit. Reinf. lever reinforcers received3.34.712.73.23.6-3.0-1.72.92.61.52.62.4-1.00.81.1-1.0-1.10.2
Conditioned reinforcement - actives0.40.41.40.60.6-0.4-0.70.30.60.40.70.1-0.7-0.1-0.41.20.5-0.7
Conditioned reinforcement - inactives1.01.12.91.11.0-1.1-1.71.11.31.71.30.8-1.00.70.6-0.4-0.4-0.3
Conditioned locomotion1.51.84.21.91.7-1.7-2.01.71.81.71.10.9-0.80.90.7-0.2-0.7-0.6
Patch foraging indifference point 0 sec1.82.97.72.32.8-1.8-1.91.72.62.02.60.7-0.60.70.40.10.3-1.5
Patch foraging indifference point AUC0.50.51.20.80.7-0.3-0.60.20.80.40.9-0.2-0.6-0.6-0.91.01.0-1.1
Delay disc. indifference point, 0s delay0.40.52.2-0.6-0.20.51.0-0.5-0.3-0.8-1.5-0.51.1-0.6-0.2-0.0-0.00.0
Delay disc. indifference point, 16s delay0.70.73.00.81.0-0.8-0.30.71.70.20.30.5-1.2-0.60.6-0.9-0.9-0.4
Delay disc. indifference point, 2s delay1.61.73.91.31.9-1.5-1.81.41.62.0-0.51.10.71.21.2-1.0-1.00.5
Delay disc. indifference point, 24s delay1.31.25.01.21.6-1.0-1.40.82.21.21.20.4-1.3-0.20.2-0.0-0.0-1.2
Delay disc. indifference point, 4s delay0.60.62.4-0.1-0.2-0.30.00.40.00.0-0.60.80.10.41.1-1.6-1.61.3
Delay disc. indifference point, 8s delay0.40.41.3-0.00.2-0.3-0.50.31.00.7-0.40.10.60.11.0-1.1-1.10.1
Indifference point function ln k0.50.72.2-0.10.2-0.5-0.00.50.80.20.90.90.90.81.4-1.5-1.31.0
Indifference point function log k0.50.72.2-0.10.2-0.5-0.00.50.80.20.90.90.90.81.4-1.5-1.31.0
Patch foraging total patch changes 0 sec2.03.38.72.52.9-2.0-2.01.92.82.02.50.9-0.90.80.6-0.10.1-1.4
Patch foraging total patch changes 12 sec1.52.06.42.12.5-1.1-1.21.01.11.21.0-0.2-0.4-0.2-1.11.71.7-2.0
Patch foraging total patch changes 18 sec0.91.23.51.71.6-1.0-0.60.91.20.41.80.5-1.9-0.5-0.50.40.5-1.2
Patch foraging total patch changes 24 sec2.32.86.62.32.5-2.0-1.91.92.61.92.21.3-0.80.70.9-0.3-0.6-0.7
Patch foraging total patch changes 6 sec1.31.94.01.92.0-1.6-1.61.51.91.61.81.0-1.10.70.6-0.2-0.2-0.6
Patch foraging time to switch 0 sec0.20.31.8-0.4-0.70.30.6-0.3-1.3-0.5-1.2-0.3-0.20.30.10.1-0.20.4
Patch foraging water rate 0 sec1.21.85.51.41.4-1.3-1.91.22.31.92.00.6-0.40.70.9-0.8-0.6-0.9
Patch foraging water rate 12 sec1.01.55.3-0.6-0.6-0.3-0.50.30.90.71.01.4-0.01.01.9-2.3-2.01.7
Patch foraging water rate 18 sec1.82.54.10.50.8-1.2-1.51.31.31.91.32.01.32.02.0-2.0-1.81.8
Patch foraging water rate 24 sec0.40.51.30.30.5-0.6-0.70.50.31.00.51.10.60.80.6-0.8-0.51.0
Patch foraging water rate 6 sec1.42.04.80.40.5-1.1-1.21.21.81.50.91.30.71.32.2-2.2-2.21.1
Seeking ratio, delayed vs. immediate footshock0.50.61.3-0.4-0.70.80.3-0.8-0.3-0.50.4-1.00.0-0.8-1.01.01.0-1.1
Distance traveled before self-admin0.91.06.30.20.2-0.50.60.5-0.3-0.7-0.51.6-2.5-0.10.2-0.8-0.81.7
Distance traveled after self-admin0.70.83.40.20.2-0.21.10.1-0.8-1.40.51.4-1.8-0.7-0.80.10.21.3
Extensor digitorum longus weight4.317.132.6-3.9-4.44.93.8-5.0-2.4-4.1-3.3-5.7-1.3-4.8-4.23.93.9-4.5
Bone: elastic displacement0.91.03.5-0.8-1.10.0-0.60.1-0.00.70.51.10.61.41.3-1.4-1.41.9
Bone: elastic work1.92.44.50.50.0-1.3-2.11.41.52.00.71.6-0.32.12.1-1.9-2.01.4
Bone: endosteal estimation6.714.740.86.46.2-5.5-4.15.43.33.41.43.8-4.41.91.2-0.9-0.8-0.2
Bone: endosteal perimeter8.617.945.06.76.6-5.8-4.75.74.13.81.84.3-5.71.81.1-0.9-0.8-0.1
Epididymis fat weight0.51.14.40.90.5-0.6-1.10.62.00.80.0-0.8-1.8-0.50.20.0-0.2-2.1
Delta time in closed arm before/after self-admin1.11.02.70.50.3-0.9-1.20.9-0.21.5-0.81.2-0.11.61.1-1.0-0.91.4
Delta time in open arm before/after self-admin2.92.85.1-1.2-0.81.72.0-1.8-0.4-2.2-0.2-2.20.9-2.2-1.91.81.8-1.9
Diff in mean of infusions in LGA sessions0.90.92.4-1.3-1.51.41.1-1.3-0.9-1.00.3-0.9-0.0-0.8-0.80.70.6-0.3
Delay discount exponential model param0.60.61.6-0.8-1.00.91.1-0.8-1.3-1.10.3-0.60.6-0.2-0.60.70.70.0
Extinction: sum of active levers before priming1.31.33.40.00.30.61.2-0.7-0.1-1.30.8-0.90.4-1.7-1.81.71.8-1.4
Active lever presses in extinction session 60.70.72.31.51.1-1.2-0.31.21.00.10.60.6-1.1-0.4-0.1-0.3-0.2-0.5
Bone: final force3.25.28.61.81.9-2.5-2.52.52.62.51.62.9-0.52.32.6-2.6-2.31.8
Bone: final moment3.65.89.41.91.9-2.7-2.72.72.62.71.63.1-0.62.52.8-2.7-2.52.0
Food consumed during 24 hour testing period1.21.55.11.31.1-0.7-1.50.61.31.10.9-0.3-2.3-0.3-0.91.11.3-1.9
Glucose0.50.82.3-1.1-1.01.01.4-1.0-1.0-1.5-0.5-0.1-0.5-0.9-0.60.20.30.5
Heart weight0.20.31.9-0.10.00.20.3-0.30.6-0.30.80.3-1.4-0.8-0.4-0.00.4-0.3
Delay discount hyperbolic model param0.50.51.5-0.7-1.00.81.0-0.7-1.2-1.00.3-0.50.2-0.2-0.70.70.7-0.0
Intermittent access intake day 1-15 change0.50.52.30.3-0.20.00.3-0.0-1.0-0.7-1.5-0.4-1.3-0.5-0.90.40.8-0.4
Intermittent access intake escalation0.40.42.0-0.1-0.50.30.3-0.3-1.1-0.5-1.4-0.6-0.6-0.2-0.80.40.8-0.3
Intermittent access intake escalation 20.30.32.40.60.1-0.3-0.30.4-0.60.0-1.6-0.3-0.80.1-0.40.20.5-0.4
Intermitt. access day 1 inactive lever presses3.74.08.02.72.8-2.6-1.92.62.21.82.62.2-0.81.31.3-1.7-1.10.5
Intermitt. access day 15 inactive lever presses1.51.64.11.61.1-1.5-0.81.61.80.50.60.4-0.70.11.5-2.0-1.7-0.7
Intermitt. access escalation Index1.31.13.0-1.4-1.11.11.4-1.2-1.7-1.2-0.90.20.3-0.4-0.90.60.71.4
Intermittent access day 1 total infusions1.01.13.21.01.2-1.0-1.40.91.81.41.81.0-0.90.40.5-0.2-0.2-0.2
Intermittent access day 15 total infusions0.40.41.50.50.3-0.2-0.90.10.50.60.2-0.1-1.2-0.1-0.60.91.0-0.9
Intermittent access terminal intake (last 3 days)0.91.02.21.51.4-1.1-1.51.01.21.00.30.3-1.50.2-0.30.60.6-1.0
Intermittent access total infusions1.61.84.41.71.7-1.4-2.11.31.71.81.60.9-1.40.80.10.50.4-0.7
Intermittent access day 1 locomotion3.63.89.12.22.0-2.1-3.02.02.63.02.01.6-1.91.41.1-0.2-0.8-0.3
Intermittent access day 15 total locomotion3.13.410.82.32.1-2.0-3.31.91.93.11.51.2-1.41.70.40.80.3-0.7
Intermittent access total locomotion5.36.016.13.02.7-2.7-4.02.73.03.82.71.7-1.92.01.1-0.0-0.5-0.9
Intermittent access standard deviation0.80.92.71.10.6-0.9-1.61.01.01.40.70.2-1.01.00.6-0.6-0.2-0.7
Left kidney weight0.51.49.1-0.8-0.40.1-0.4-0.11.10.53.01.50.60.61.1-1.2-1.31.3
Right kidney weight0.82.25.1-0.00.2-0.7-1.70.71.21.92.32.00.82.11.7-1.5-1.41.8
Cocaine induced anxiety1.21.46.00.2-0.1-0.8-0.60.81.20.80.41.0-0.60.72.0-2.2-2.50.9
Post-drug Anxiety1.31.46.40.1-0.4-0.7-0.30.71.00.4-0.70.8-0.90.42.0-2.3-2.50.9
Baseline Anxiety0.20.30.8-0.8-0.90.60.4-0.6-0.4-0.3-0.8-0.30.50.00.2-0.3-0.20.3
Tail length1.23.57.42.72.7-2.4-2.72.32.42.51.11.1-1.61.50.7-0.20.0-0.9
Length with tail1.76.413.73.43.5-3.4-3.73.32.53.50.62.6-1.52.51.4-0.8-0.70.5
Length without tail1.12.34.31.61.6-1.9-2.11.90.62.0-0.91.80.31.91.3-1.1-1.11.4
Times rat made contact with spout0.60.71.81.10.9-1.1-1.31.10.61.1-0.00.8-0.90.70.4-0.1-0.30.1
Lifetime Intake1.82.15.51.81.9-1.5-1.91.52.11.62.41.0-1.10.70.30.20.2-0.8
Liver weight, left0.81.23.01.41.7-1.5-1.61.40.81.40.41.20.21.40.4-0.10.10.7
Liver weight, right1.11.84.2-0.10.1-0.7-1.40.71.51.61.11.21.41.62.0-2.0-1.71.3
Locomotor activity0.91.514.50.50.8-0.4-1.00.30.41.03.81.2-0.10.8-0.50.90.90.3
Locomotor testing distance1.11.817.61.01.2-0.5-0.50.50.80.34.20.8-1.3-0.2-0.81.20.9-0.6
Locomotor testing rearing0.81.26.70.60.40.10.1-0.0-0.8-0.22.6-0.0-1.4-0.5-1.51.91.5-0.8
Locomotion in novel chamber1.01.33.40.70.4-1.0-1.41.0-0.11.3-0.21.9-0.51.51.2-0.8-1.31.8
Locomotion in novel chamber post-restriction1.72.15.72.02.4-2.0-1.61.91.81.6-0.31.4-1.11.00.8-0.4-0.60.2
Fecal boli incidents, locomotor time 10.70.72.40.00.00.31.3-0.3-0.2-1.6-1.1-0.4-1.0-1.5-0.90.60.6-0.5
Change in fecal boli incidents, locomotor task0.30.20.5-0.6-0.70.50.1-0.50.4-0.2-0.5-0.7-0.3-0.60.3-0.4-0.4-0.7
Time >=10cm from walls, locomotor time 10.90.92.9-1.3-1.20.91.3-0.9-1.6-1.2-0.20.60.4-0.2-0.40.00.01.7
Bouts of movement, locomotor time 10.40.41.4-0.9-1.10.80.3-0.7-0.1-0.0-0.7-1.20.9-0.20.3-0.3-0.3-0.7
Total resting periods, locomotor time 10.50.51.3-0.9-1.10.70.2-0.6-0.00.1-1.1-1.21.0-0.10.6-0.6-0.6-0.6
Rest time, locomotor task time 10.60.74.5-0.3-0.10.11.0-0.1-0.3-1.1-2.1-0.71.1-0.40.5-0.7-0.70.1
Distance moved, locomotor task time 11.01.14.40.70.5-0.7-2.10.70.92.11.50.6-0.91.30.5-0.1-0.1-0.2
Vertical activity count, locomotor time 11.31.33.60.90.7-1.0-1.91.00.91.81.31.3-0.51.41.0-0.9-0.90.7
Time >=10cm from walls, locomotor time 20.60.62.50.1-0.4-0.5-0.30.6-0.80.2-0.91.0-0.51.10.8-1.0-1.01.6
Bouts of movement, locomotor time 21.01.13.2-0.8-1.11.01.8-1.0-0.1-1.8-0.2-1.3-0.3-1.8-0.60.00.0-1.0
Total resting periods, locomotor time 21.21.34.0-1.1-1.21.22.0-1.2-0.4-2.0-0.3-1.3-0.2-1.8-0.6-0.0-0.0-0.8
Rest time, locomotor task time 22.93.310.0-2.0-1.61.83.2-1.9-1.4-2.9-2.7-1.41.1-2.2-0.70.10.10.0
Distance moved, locomotor task time 21.51.76.30.90.2-1.0-2.41.10.22.41.00.90.12.51.2-0.6-0.60.6
Vertical activity count, locomotor time 21.82.04.91.81.3-1.7-2.21.71.12.01.81.0-0.11.91.0-0.6-0.6-0.1
Light reinforcement 10.40.82.9-0.00.40.30.5-0.31.6-0.31.7-1.00.5-1.0-0.40.20.6-1.7
Light reinforcement 20.50.73.90.61.0-0.6-0.20.62.00.10.5-0.41.0-0.50.6-0.9-0.7-1.0
Bone: marrow area6.714.539.96.36.1-5.5-4.15.43.23.41.33.8-4.41.91.2-0.9-0.9-0.1
Bone: maximum diameter5.29.617.64.14.1-4.2-3.14.13.72.71.73.7-2.71.82.3-2.3-2.21.2
Bone: maximum force3.25.611.42.32.5-2.7-2.62.73.42.62.12.7-1.41.82.3-2.2-2.00.9
Bone: maximum moment3.66.111.62.42.5-2.9-2.92.83.42.81.92.8-1.42.12.5-2.4-2.21.0
Mean time between licks in bursts0.20.32.60.20.3-0.10.0-0.00.6-0.20.2-0.0-1.6-0.9-0.40.40.2-0.6
Mean num. licks in bursts0.20.21.30.2-0.0-0.0-0.40.00.70.30.2-0.7-0.3-0.40.00.3-0.1-1.1
Cd content in liver3.13.56.3-2.3-2.32.51.8-2.4-2.5-1.6-1.8-2.01.3-1.2-1.41.41.4-0.4
Co content in liver1.61.94.3-1.1-1.51.51.1-1.5-2.1-1.1-0.7-1.3-0.1-0.9-1.81.91.8-0.5
Cu content in liver0.20.21.30.40.3-0.30.10.30.4-0.1-1.2-0.60.3-0.20.2-0.1-0.3-0.7
Fe content in liver0.40.41.8-0.5-0.10.61.2-0.6-0.7-1.10.3-0.41.3-0.5-0.30.40.20.1
K content in liver0.90.93.31.41.8-1.3-0.91.20.40.9-0.81.00.41.00.10.10.20.6
Mg content in liver0.70.73.40.10.40.10.3-0.1-0.5-0.1-1.8-0.91.90.1-0.60.81.0-0.4
Mn content in liver1.21.35.30.71.4-1.0-0.81.00.61.2-0.11.12.31.61.1-0.8-0.71.3
Na content in liver0.40.41.60.81.3-0.60.20.60.1-0.31.10.80.6-0.0-0.50.50.60.5
Rb content in liver1.62.07.6-1.8-1.21.51.7-1.5-2.0-1.2-1.3-0.82.8-0.1-0.50.60.50.9
Se content in liver0.81.01.9-1.2-0.81.31.4-1.4-1.0-1.3-0.3-0.71.0-1.0-1.01.10.90.0
Sr content in liver1.61.42.50.90.7-1.3-1.41.31.31.31.11.6-1.21.01.2-1.2-1.20.9
Zn content in liver0.70.82.20.71.1-1.0-0.91.01.10.90.21.50.10.60.7-0.4-0.71.2
Bone: minimum diameter7.914.832.05.75.3-5.2-4.65.04.63.92.53.7-4.71.91.7-1.4-1.4-0.3
Time in familiar zone, hab. session 11.21.12.90.30.40.40.5-0.5-0.6-0.7-1.1-1.2-1.1-1.2-1.61.51.7-1.6
Time in novel zone, hab. session 10.90.92.9-0.7-0.90.10.20.00.4-0.01.10.70.90.61.4-1.6-1.71.3
Total zone transitions, hab. session 10.40.62.90.20.2-0.2-1.30.10.61.31.70.4-0.60.8-0.10.20.5-0.2
Total locomotion distance, hab. session 12.43.49.31.21.1-1.6-2.71.61.93.12.51.60.02.41.8-1.6-1.20.6
Locomotion velocity, hab. session 12.33.310.11.41.4-1.7-2.91.71.83.22.11.5-0.22.41.5-1.3-0.90.5
Time in familiar zone, hab. session 21.01.03.60.70.50.10.1-0.2-0.6-0.40.7-0.3-1.2-0.8-1.71.91.9-1.0
Time in novel zone, hab. session 21.71.76.2-0.5-0.3-0.4-0.30.51.00.7-0.80.51.41.22.2-2.5-2.41.2
Total zone transitions, hab. session 20.40.52.9-0.2-0.10.4-0.4-0.5-0.30.51.7-0.20.00.3-0.91.01.3-0.4
Total locomotion distance, hab. session 20.60.73.00.30.6-0.1-1.20.10.91.51.7-0.40.80.8-0.00.30.6-1.0
Locomotion velocity, hab. session 20.50.72.70.30.6-0.2-1.40.10.91.61.6-0.40.70.90.00.20.6-0.9
Novel to familiar place preference ratio0.50.51.30.70.6-0.8-0.70.81.10.40.60.7-1.00.20.7-0.6-0.90.2
Novelty place preference0.30.30.70.50.4-0.6-0.50.60.80.20.70.7-0.70.20.6-0.6-0.80.3
Time in novel zone, NPP test0.40.40.90.40.3-0.6-0.40.70.70.20.90.9-0.60.30.8-0.7-1.00.6
Total zone transitions, NPP test0.60.85.60.10.6-0.2-1.10.10.91.52.40.50.81.00.2-0.00.30.1
Total locomotion distance, NPP test1.52.17.40.91.2-1.2-2.31.21.42.71.80.80.92.11.2-1.0-0.60.2
Locomotion velocity, NPP test0.81.14.20.50.9-0.6-1.70.51.52.01.80.10.51.10.6-0.5-0.0-0.7
Intraocular pressure0.81.14.40.30.20.10.5-0.21.6-0.71.1-0.8-1.9-1.9-0.40.40.1-2.1
Delta distance traveled before/after self-admin0.50.62.4-0.6-0.70.70.8-0.7-0.7-0.91.5-0.21.2-0.5-0.60.40.40.1
Delta ambulatory time before/after self-admin0.20.22.2-0.00.00.10.2-0.1-0.2-0.21.0-0.11.5-0.1-0.20.20.2-0.1
Parametrial fat weight2.14.19.21.91.7-2.4-3.02.42.33.0-1.21.20.22.42.3-2.1-1.70.4
Pavlov. Cond. lever latency3.24.06.3-2.1-1.82.42.5-2.4-1.7-2.4-2.5-2.40.5-2.4-1.61.51.3-1.3
Pavlov. Cond. magazine entry latency2.93.86.62.62.4-2.5-2.32.61.92.22.12.0-0.52.11.3-1.2-0.90.6
Pavlov. Cond. change in total contacts2.32.55.52.01.6-2.0-1.92.01.51.72.31.5-0.41.61.0-1.0-0.80.5
Pavlov. Cond. index score3.03.87.22.42.2-2.5-2.32.51.92.12.72.2-0.62.01.2-1.2-0.90.8
Pavlov. Cond. latency score2.53.27.72.21.9-2.2-2.22.21.62.02.82.1-0.71.91.0-1.0-0.70.8
Pavlov. Cond. lever contacts1.92.23.71.71.3-1.8-1.91.91.11.81.81.7-0.81.81.0-0.9-0.80.8
Pavlov. Cond. magazine entry number2.43.05.3-2.2-2.12.32.0-2.3-1.8-1.8-2.1-1.7-0.1-1.9-1.41.31.0-0.6
Pavlov. Cond. intertrial magazine entries1.21.44.70.51.00.30.6-0.41.0-0.71.2-0.9-1.0-1.9-1.41.61.4-2.2
Pavlov. Cond. lever-magazine prob. diff.3.03.76.72.42.1-2.4-2.22.51.92.02.62.2-0.81.91.4-1.4-1.10.9
Pavlov. Cond. response bias4.55.59.32.72.4-3.0-2.73.02.22.52.22.5-0.22.72.2-2.1-1.81.3
Pavlov. Cond. lever latency0.30.41.2-0.8-1.00.80.4-0.8-0.5-0.3-0.9-1.10.2-0.4-0.20.10.2-0.6
Pavlov. Cond. magazine entry latency1.11.23.3-1.4-1.31.21.5-1.2-1.8-1.4-1.00.10.6-0.5-0.70.60.41.3
Pavlov. Cond. change in total contacts0.20.31.50.60.9-0.20.10.2-0.3-0.20.60.4-0.0-0.3-0.81.20.90.0
Pavlov. Cond. index score0.20.21.10.20.3-0.20.30.2-0.4-0.30.41.0-0.20.1-0.10.2-0.01.0
Pavlov. Cond. latency score0.20.31.80.10.3-0.30.30.3-0.5-0.30.41.2-0.20.30.1-0.0-0.21.3
Pavlov. Cond. lever contacts0.20.30.70.60.8-0.6-0.40.60.50.40.90.70.00.40.3-0.1-0.20.2
Pavlov. Cond. magazine entry number1.11.33.61.61.4-1.2-1.41.21.91.20.7-0.3-1.00.20.3-0.3-0.1-1.7
Pavlov. Cond. intertrial magazine entries4.76.115.53.93.6-3.1-2.83.03.72.30.30.3-3.00.40.6-0.5-0.2-2.7
Pavlov. Cond. lever-magazine prob. diff.0.20.21.20.10.3-0.20.30.1-0.5-0.40.21.0-0.10.1-0.10.2-0.01.1
Pavlov. Cond. response bias0.10.10.50.20.5-0.3-0.10.20.00.00.40.70.20.30.10.1-0.10.6
Time in closed arm before self-admin0.60.72.6-1.0-1.00.50.1-0.4-0.70.21.60.51.01.00.6-0.4-0.61.2
Time in closed arm after self-admin1.01.04.0-0.5-0.70.1-0.80.0-1.61.1-0.41.00.91.90.60.1-0.32.0
Time in open arm before self-admin0.40.51.4-0.2-0.6-0.1-0.10.1-0.50.1-1.20.7-1.10.30.6-0.8-0.91.1
Time in open arm after self-admin1.21.34.7-0.1-0.10.61.2-0.70.5-1.6-0.8-1.2-1.3-2.2-1.30.80.9-1.8
Bone: periosteal estimation7.515.530.35.55.3-5.4-4.35.34.43.82.64.3-3.52.62.6-2.5-2.40.8
Bone: periosteal perimeter6.711.219.24.14.0-4.4-3.74.33.63.22.34.4-3.42.22.4-2.5-2.31.8
Bone: post-yield work1.62.26.92.11.9-1.9-1.81.91.31.50.61.7-2.60.60.4-0.5-0.40.2
Progressive ratio test 1 active lever presses3.23.37.02.42.6-2.1-2.32.02.52.22.71.7-1.10.90.50.1-0.3-0.4
Progressive ratio test 1 breakpoint3.33.48.72.52.8-2.1-2.12.02.71.92.91.5-1.40.40.10.3-0.0-0.8
Progressive ratio test 1 inactive lever presses2.73.011.32.32.7-1.9-1.51.82.41.33.41.6-1.20.3-0.00.30.2-0.5
Progressive ratio test 2 active lever presses3.23.57.02.62.6-2.4-2.62.32.62.41.41.4-1.40.91.0-0.1-0.7-0.7
Progressive ratio test 2 breakpoint3.64.08.42.92.8-2.6-2.72.52.72.51.21.6-1.80.90.9-0.1-0.8-0.6
Progressive ratio test 2 inactive lever presses2.42.87.12.22.3-1.9-2.41.82.72.01.70.8-1.40.60.60.1-0.1-1.3
Incentive Sensitization - Responses1.81.84.52.12.1-1.8-1.81.71.61.5-0.11.0-1.50.40.40.2-0.3-0.5
Incentive Sensitization - Breakpoint1.81.84.52.12.1-1.8-1.81.81.51.5-0.21.1-1.50.60.50.2-0.3-0.3
Sum of active levers in priming session hrs 5-62.62.54.9-0.9-0.61.42.2-1.4-1.0-2.20.3-1.21.5-1.9-2.22.02.0-0.9
Progressive ratio0.20.32.80.10.5-0.2-0.30.2-0.10.4-1.70.2-0.60.2-0.10.10.00.4
Food seeking constrained by brief footshock1.01.22.91.71.5-1.0-1.21.0-0.10.8-0.20.1-1.60.2-1.31.51.4-1.0
Seeking ratio, punishment vs. effort0.30.42.10.90.5-0.4-0.40.50.20.01.4-0.0-0.5-0.1-0.50.60.5-0.8
Retroperitoneal fat weight0.92.810.61.91.6-1.6-3.31.61.83.20.80.4-0.72.00.7-0.10.2-1.2
Reaction time number correct0.20.20.8-0.5-0.00.0-0.1-0.10.60.20.10.80.10.10.5-0.8-0.60.9
Reaction time mean minus median0.40.63.0-0.7-0.90.70.8-0.6-0.8-0.7-1.7-1.00.8-0.30.0-0.1-0.2-0.4
Reaction time mean minus median AUC0.50.61.9-1.1-0.90.91.0-0.9-0.7-0.8-1.0-0.61.4-0.20.1-0.2-0.20.3
Reaction time num false alarms2.12.86.72.42.5-2.1-1.62.01.81.42.62.1-1.50.70.3-0.2-0.10.3
Reaction time num false alarms AUC2.43.37.42.62.7-2.4-2.02.32.11.82.32.2-0.81.10.5-0.4-0.30.3
Reaction time trials correct on left0.20.20.8-0.5-0.00.0-0.1-0.10.60.20.10.80.10.10.5-0.8-0.60.9
Reaction time trials on left0.20.30.9-0.50.0-0.0-0.1-0.00.70.20.10.80.10.20.7-0.9-0.70.9
Reaction time mean0.60.93.5-0.9-0.80.71.2-0.6-1.3-0.8-1.5-0.51.90.20.4-0.5-0.50.6
Reaction time mean AUC0.91.34.3-1.1-1.11.01.6-0.9-1.7-1.3-1.6-0.82.10.00.1-0.4-0.30.6
Median of all reaction times0.60.83.3-0.8-0.70.61.2-0.5-1.3-0.8-1.2-0.41.80.20.4-0.6-0.50.8
Reaction time omissions0.71.03.40.40.3-0.70.00.70.70.1-1.7-0.00.90.41.6-1.8-1.80.2
Reaction time false alarm rate1.52.15.82.42.2-2.0-1.62.01.31.31.81.5-0.90.80.20.00.0-0.0
Reaction time premature initiation rate0.50.72.70.80.6-0.6-0.50.61.60.31.60.1-1.5-0.70.20.1-0.5-1.0
Reaction time premature initiations0.50.63.40.50.7-0.5-0.50.51.80.41.40.4-1.3-0.60.3-0.1-0.5-0.6
Std. dev. reaction times0.60.84.8-0.6-0.80.50.7-0.5-1.0-0.5-2.2-1.01.60.20.4-0.5-0.40.0
Reaction time trials completed0.20.30.9-0.50.0-0.0-0.1-0.00.70.20.10.80.10.20.7-0.9-0.70.9
Reaction time trials AUC0.10.20.7-0.5-0.00.1-0.1-0.10.60.20.10.70.20.10.5-0.8-0.60.8
Run reversals in cocaine runway, females0.80.72.1-0.7-1.40.3-0.4-0.20.30.3-1.4-0.8-0.50.11.0-1.5-1.4-0.4
Run reversals in cocaine runway, males0.30.31.20.1-0.1-0.30.20.30.3-0.1-0.40.6-0.5-0.10.7-1.1-1.00.6
Latency to leave start box in cocaine runway0.20.20.8-0.5-0.60.30.8-0.3-0.4-0.90.10.20.2-0.40.0-0.4-0.40.6
Latency to leave start box in cocaine runway, F0.60.61.9-0.5-0.70.10.6-0.0-0.1-0.61.11.1-0.6-0.00.7-1.2-1.31.4
Latency to leave start box in cocaine runway, M0.80.82.3-0.4-0.30.60.5-0.6-0.8-0.6-1.5-1.21.5-0.4-0.81.00.9-0.7
Std. dev. time between licks in bursts0.30.31.0-0.4-0.30.60.4-0.60.0-0.40.6-0.9-0.1-0.7-0.60.40.6-1.0
Total sessions with >9 infusions0.70.87.30.20.7-0.2-0.80.11.40.92.70.50.10.20.00.40.4-0.4
Short access day 1 total inactive lever presses1.92.24.21.31.2-1.5-2.01.51.52.01.91.7-0.91.51.4-1.2-1.10.7
Short access day 10 total inactive lever presses0.30.41.50.50.5-0.20.40.10.8-0.50.4-0.6-0.6-0.9-0.4-0.50.5-1.2
Short access day 1 total infusions1.21.311.80.71.1-0.4-0.60.31.60.53.40.6-0.2-0.2-0.40.70.7-0.7
Short access day 10 total infusions2.62.96.82.42.3-1.9-1.91.82.51.52.61.0-1.80.30.2-0.20.2-1.2
Short access total infusions1.92.112.01.81.9-1.4-1.21.32.00.93.51.2-1.00.30.10.20.3-0.6
Short access day 1 locomotion2.22.39.51.71.8-1.3-1.61.22.81.33.10.7-1.6-0.10.30.2-0.1-1.4
Short access day 10 total locomotion4.75.312.73.22.8-2.5-3.62.42.83.32.41.0-2.41.40.30.60.4-1.8
Short access total locomotion3.03.111.52.01.8-1.5-2.31.52.42.13.40.9-1.90.70.10.60.4-1.3
One hour access (0.3 mA shock)0.40.51.41.11.1-0.7-0.30.70.6-0.10.90.7-1.2-0.3-0.50.60.5-0.3
Compulsive drug intake0.80.83.5-0.4-0.5-0.2-0.10.2-0.30.3-0.31.2-0.20.81.3-1.3-1.51.9
One hour access (shock baseline)0.60.72.30.90.9-0.3-0.50.20.50.10.8-0.4-0.3-0.4-1.21.31.5-1.4
Social response proportion0.20.20.9-0.5-0.60.50.5-0.5-0.2-0.5-0.2-0.1-0.3-1.0-0.50.10.2-0.2
Social responses0.20.32.60.00.10.1-0.0-0.10.10.11.60.30.3-0.3-0.50.60.5-0.1
Social time0.30.41.60.50.1-0.40.40.40.0-0.7-1.20.4-1.2-0.90.0-0.3-0.60.1
Soleus weight0.31.04.70.80.6-0.8-0.60.81.20.22.21.4-1.7-0.00.3-0.5-0.50.5
Bone: stiffness0.81.33.71.41.9-1.3-1.31.21.41.31.21.5-0.60.70.4-0.2-0.10.4
Tibialis anterior weight1.03.410.0-0.7-1.31.60.7-1.60.0-1.2-0.3-2.6-1.9-2.3-2.32.32.3-3.2
Time to tail flick, vehicle, before self-admin1.81.95.00.70.5-1.3-0.51.30.40.5-1.91.60.40.81.8-2.1-2.21.8
Time to tail flick, vehicle, after self-admin0.50.62.21.01.5-0.9-0.10.81.40.2-1.00.1-0.5-0.60.2-0.2-0.3-0.6
Time to tail flick, test, before self-admin1.00.95.7-0.8-1.30.80.7-0.8-1.5-0.8-2.4-0.8-0.2-0.3-0.50.30.30.0
Time to tail flick, test, after self-admin0.20.20.90.0-0.1-0.20.20.20.4-0.2-0.10.3-0.2-0.00.7-0.9-0.90.4
Delta time to tail flick, vehicle, before/after SA0.80.73.40.91.3-0.5-0.40.41.10.5-0.1-1.0-0.2-0.3-0.60.91.0-1.8
Delta time to tail flick, test, before/after SA0.20.20.60.20.7-0.3-0.00.30.60.10.80.40.60.10.2-0.2-0.10.2
Tibia length1.23.46.50.71.1-1.5-2.21.51.72.32.02.5-0.22.32.1-1.9-1.82.0
Ambulatory time before self-admin0.80.85.70.40.4-0.60.10.6-0.2-0.1-0.21.6-2.40.20.1-0.5-0.51.6
Ambulatory time after self-admin0.60.72.70.60.6-0.70.40.6-0.1-0.61.01.5-1.6-0.2-0.0-0.6-0.41.2
Bone: tissue strength0.20.20.8-0.8-0.30.40.2-0.5-0.30.0-0.00.40.70.50.3-0.1-0.10.9
Total heroin consumption0.70.82.61.21.2-1.2-0.21.20.40.21.11.60.20.50.5-0.6-0.71.2
Bone: trabecular number4.97.711.92.83.0-3.4-3.13.42.83.31.22.90.63.03.1-2.8-2.71.7
Bone: trabecular spacing3.03.97.2-1.6-1.62.21.9-2.3-2.2-2.0-0.8-1.9-0.6-2.1-2.72.62.5-1.3
Bone: trabecular thickness6.47.611.72.72.5-3.4-3.13.43.43.00.22.4-0.62.73.4-3.3-3.21.1
Bone: trabecular tissue density0.60.82.4-0.8-0.20.1-0.2-0.11.30.40.60.41.20.61.6-1.4-1.50.6
Water consumed over 24 hours0.30.41.50.20.1-0.5-1.20.50.81.20.50.4-0.20.90.7-0.5-0.60.1
Number of responses in last shaping day1.41.42.91.30.9-1.3-1.01.31.50.91.61.4-1.70.31.0-1.2-1.30.3