Hub : Genes

Ccdc25

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Ccdc25 0.3 0.14 1.0e-04 0.14 0.08 0.11 0.12 2.6e-04 6.9e-03 1.7e-03 1.1e-03
2 IC isoform ratio NM_001108382.1 0.08 0.06 2.2e-03 0.06 0.04 0.05 0.04 2.3e-03 1.1e-02 3.0e-03 1.3e-02
3 IC isoform ratio XM_063274429.1 0.08 0.06 1.9e-03 0.06 0.04 0.05 0.03 2.1e-03 1.2e-02 3.0e-03 1.7e-02
4 Liver gene expression Ccdc25 0.37 0.15 0.0e+00 0.28 0.3 0.3 0.3 1.8e-31 3.9e-33 4.6e-33 1.5e-33
5 pVTA gene expression Ccdc25 0.41 0.12 0.0e+00 0.39 0.28 0.39 0.11 8.7e-33 1.0e-22 1.9e-33 2.8e-09
6 Brain mRNA stability Ccdc25 0.03 0.03 2.2e-03 0.02 0.03 0.02 0.02 3.2e-03 4.5e-04 4.3e-03 4.6e-03
7 NAcc gene expression Ccdc25 0.22 0.08 0.0e+00 0.28 0.12 0.3 0.1 3.1e-43 2.5e-17 2.4e-45 1.7e-14
8 IL gene expression Ccdc25 0.29 0.14 6.8e-05 0.17 0.13 0.18 0.21 7.7e-05 6.2e-04 3.6e-05 8.8e-06
9 Brain gene expression Ccdc25 0.23 0.1 0.0e+00 0.31 0.29 0.29 0.3 1.6e-29 4.1e-27 2.5e-27 7.0e-28
10 BLA isoform ratio NM_001108382.1 0.11 0.07 3.9e-04 0.05 0.04 0.02 0.03 1.5e-03 5.5e-03 2.3e-02 8.7e-03
11 BLA isoform ratio XM_063274429.1 0.12 0.07 2.0e-04 0.06 0.04 0.02 0.04 6.3e-04 3.3e-03 3.9e-02 5.0e-03
12 Brain isoform ratio NM_001108382.1 0.06 0.03 3.7e-06 0.07 0.06 0.06 0.07 3.5e-07 1.8e-06 1.9e-06 8.7e-07
13 Brain isoform ratio XM_063274429.1 0.05 0.03 7.1e-06 0.07 0.06 0.06 0.06 7.0e-07 4.4e-06 6.9e-06 1.8e-06
14 BLA gene expression Ccdc25 0.31 0.11 2.8e-14 0.21 0.2 0.2 0.21 3.2e-11 6.8e-11 9.9e-11 3.7e-11
15 PL gene expression Ccdc25 0.18 0.08 0.0e+00 0.22 0.22 0.2 0.21 1.8e-23 4.6e-23 5.7e-21 1.5e-22
16 IC gene expression Ccdc25 0.24 0.1 1.6e-10 0.24 0.11 0.2 0.13 1.4e-10 2.1e-05 7.7e-09 4.3e-06
17 Adipose gene expression Ccdc25 0.11 0.07 2.3e-09 0.06 0.06 0.05 0.05 3.4e-07 6.4e-07 1.5e-06 2.5e-06
18 PL isoform ratio XM_063274429.1 0.04 0.03 5.8e-06 0.04 0.04 0.01 0.04 5.0e-05 1.1e-05 2.0e-02 3.7e-05
19 PL isoform ratio NM_001108382.1 0.04 0.03 4.1e-06 0.04 0.05 0.02 0.04 3.1e-05 8.8e-06 6.8e-03 4.1e-05
20 NAcc isoform ratio NM_001108382.1 0.04 0.03 8.8e-07 0.04 0.04 0.04 0.04 5.2e-07 1.4e-06 2.9e-07 4.4e-06
21 NAcc isoform ratio XM_063274429.1 0.04 0.03 1.0e-06 0.04 0.04 0.05 0.03 4.2e-06 1.2e-06 1.5e-07 7.2e-06
22 OFC gene expression Ccdc25 0.36 0.17 2.9e-04 0.04 0.07 0.08 0.05 3.6e-02 9.7e-03 5.2e-03 2.9e-02
23 BLA intron excision ratio chr15_44239899_44247171 0.16 0.11 4.7e-03 0.01 0.02 0.04 0.03 4.9e-02 1.9e-02 3.1e-03 1.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.22.23.11.41.4-1.4-1.31.61.31.4-1.61.51.6-1.61.6-1.61.61.61.51.51.7-1.71.5-1.51.20.7
Area under the delay curve0.10.21.20.20.2-0.20.2-0.1-0.0-0.10.5-0.3-0.30.3-0.40.4-0.4-0.4-0.5-0.4-0.40.4-0.60.6-1.10.1
BMI with tail0.20.81.1-1.0-0.90.91.0-0.9-0.9-1.00.8-1.1-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.80.8-0.60.6-0.8-0.7
BMI without tail0.31.43.2-1.1-1.11.11.7-0.9-1.5-1.40.9-1.5-1.21.2-1.21.2-1.2-1.2-1.2-1.2-0.80.8-0.50.5-0.8-1.8
Body weight0.00.20.6-0.0-0.00.00.0-0.30.0-0.10.7-0.5-0.20.2-0.30.3-0.4-0.4-0.3-0.4-0.70.8-0.80.7-0.50.1
Weight adjusted by age0.10.20.60.10.1-0.1-0.70.00.60.40.40.20.2-0.20.2-0.20.10.1-0.20.1-0.70.7-0.70.60.10.4
Bone surface1.32.63.41.81.8-1.8-1.71.71.61.7-1.61.61.7-1.71.7-1.71.71.71.61.61.6-1.61.4-1.41.11.1
Bone volume1.32.63.41.81.8-1.8-1.61.81.61.6-1.71.61.7-1.71.7-1.71.71.71.61.61.7-1.71.4-1.40.91.0
Breakpoint value in progressive ratio session0.00.00.20.10.1-0.1-0.20.10.20.2-0.20.20.2-0.20.2-0.20.20.2-0.20.10.1-0.10.3-0.3-0.30.5
Number of licking bursts0.00.10.4-0.4-0.40.40.6-0.3-0.6-0.50.1-0.4-0.40.4-0.40.4-0.4-0.4-0.3-0.4-0.00.00.1-0.1-0.2-0.6
Context. condit. distance diff. score1.61.95.3-1.6-1.61.62.3-1.1-2.2-1.90.6-1.4-1.31.3-1.31.3-1.3-1.3-1.3-1.4-0.30.30.00.1-0.6-2.2
Locomotion velocity, session 10.80.91.90.60.6-0.6-1.00.71.11.0-0.81.01.1-1.11.1-1.11.01.01.11.00.8-0.80.5-0.50.51.4
Locomotion distance, session 12.32.97.61.21.2-1.2-2.11.12.12.0-1.41.82.0-2.01.9-1.91.91.92.01.81.2-1.20.8-0.80.92.8
Locomotion velocity, session 21.11.33.81.01.0-1.0-1.40.81.41.3-0.91.21.3-1.31.3-1.31.21.21.21.20.8-0.80.7-0.70.51.9
Locomotion distance, session 23.34.69.11.71.7-1.7-2.61.62.72.5-1.82.32.5-2.52.5-2.52.42.42.42.31.7-1.61.3-1.31.33.0
Locomotion velocity, session 32.02.33.0-1.6-1.61.61.6-1.6-1.5-1.51.6-1.5-1.41.4-1.41.4-1.6-1.6-1.3-1.5-1.61.6-1.71.7-1.2-1.2
Locomotion distance, session 30.80.91.4-1.1-1.11.11.1-0.8-1.0-1.00.8-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.70.7-1.01.1-0.8-1.2
Stereotopy head waving bouts, day 30.10.10.3-0.4-0.40.4-0.2-0.40.20.10.20.00.1-0.10.1-0.1-0.0-0.00.20.0-0.30.3-0.1-0.00.50.6
Stereotopy head waving duration, day 30.60.71.6-1.0-1.01.00.3-1.2-0.4-0.51.1-0.8-0.70.7-0.70.7-0.8-0.8-0.5-0.8-1.31.3-1.21.1-0.60.4
Locomotion velocity, session 71.11.35.8-0.9-0.90.92.0-0.5-1.9-1.50.0-1.0-1.11.1-1.11.1-1.0-1.0-1.0-1.00.3-0.30.7-0.5-0.2-2.4
Locomotion distance, session 70.50.73.60.20.2-0.20.90.7-0.8-0.5-1.20.1-0.10.1-0.10.10.00.00.00.11.3-1.41.5-1.30.3-1.9
Stereotopy head waving bouts, day 70.30.41.0-0.7-0.70.7-0.1-0.90.1-0.10.9-0.4-0.20.2-0.30.3-0.4-0.4-0.2-0.4-1.01.0-1.00.9-0.30.9
Stereotopy head waving duration, day 71.21.53.2-1.4-1.41.40.5-1.5-0.6-0.81.7-1.1-1.01.0-1.01.0-1.1-1.1-0.9-1.1-1.81.8-1.81.7-0.70.1
Locomotion velocity, session 80.50.61.4-1.2-1.21.20.9-1.0-0.8-0.70.8-0.7-0.60.6-0.60.6-0.6-0.6-0.6-0.7-0.60.6-0.50.6-0.7-0.1
Locomotion distance, session 80.20.20.6-0.1-0.10.1-0.00.10.10.2-0.60.50.6-0.60.6-0.60.60.60.60.50.7-0.80.7-0.60.30.5
Degree of sensitization distance1.51.65.51.31.3-1.3-0.11.50.10.4-1.90.90.8-0.80.7-0.70.80.80.90.92.0-2.02.4-2.31.0-0.9
Degree of sensitization stereotypy0.70.71.7-0.9-0.90.90.4-1.1-0.4-0.61.2-0.8-0.70.7-0.70.7-0.8-0.8-0.6-0.8-1.21.2-1.31.3-0.80.2
Conditioned locomotion0.10.20.9-0.6-0.60.60.6-0.2-0.6-0.5-0.1-0.2-0.30.3-0.20.2-0.2-0.2-0.2-0.20.1-0.2-0.00.1-0.0-0.9
Cocaine response after cond. corrected1.21.83.0-1.5-1.51.51.7-1.2-1.7-1.61.0-1.4-1.41.4-1.31.3-1.4-1.4-1.4-1.4-0.70.7-0.80.9-1.3-1.6
Cocaine response after cond. not corrected0.50.71.3-1.0-1.01.01.1-0.8-1.1-1.10.6-0.8-0.80.8-0.80.8-0.8-0.8-0.9-0.8-0.30.3-0.30.4-1.0-0.9
Cocaine response before conditioning2.22.63.41.81.8-1.8-1.81.51.81.7-1.51.61.7-1.71.6-1.61.71.71.61.61.3-1.31.4-1.41.31.7
Saline control response0.91.32.01.31.3-1.3-1.41.21.41.4-0.91.11.2-1.21.2-1.21.21.21.31.10.7-0.70.5-0.61.01.2
Bone: connectivity density2.13.35.71.41.4-1.4-1.31.81.31.5-2.11.71.9-1.91.9-1.91.91.91.91.82.2-2.22.2-2.22.40.2
Bone: cortical apparent density1.01.63.6-0.8-0.80.81.5-0.8-1.5-1.51.1-1.4-1.41.4-1.41.4-1.4-1.4-1.1-1.4-0.90.9-0.90.9-1.0-1.9
Bone: cortical area0.10.20.90.70.7-0.7-0.60.40.60.5-0.10.20.3-0.30.3-0.30.30.30.20.30.1-0.0-0.30.2-0.70.9
Bone: cortical porosity0.20.21.8-0.1-0.10.1-0.4-0.30.40.30.40.00.1-0.10.1-0.10.10.1-0.00.1-0.50.5-0.60.6-0.31.3
Bone: cortical porosity0.20.21.80.10.1-0.1-0.6-0.20.60.50.40.10.2-0.20.2-0.20.20.20.10.2-0.50.5-0.70.7-0.21.4
Bone: cortical thickness0.10.21.20.10.1-0.10.2-0.2-0.1-0.20.5-0.5-0.40.4-0.40.4-0.4-0.4-0.5-0.4-0.50.5-0.60.6-1.10.2
Bone: cortical thickness0.81.02.9-0.8-0.80.81.3-0.9-1.1-1.10.8-1.2-1.01.0-1.01.0-1.0-1.0-1.0-1.1-0.60.6-0.60.6-1.7-0.7
Bone: cortical tissue density1.21.84.0-0.9-0.90.91.7-1.0-1.7-1.61.2-1.5-1.51.5-1.51.5-1.5-1.5-1.2-1.5-1.01.0-1.01.0-1.0-2.0
Condit. Reinf. active minus inactive responses0.10.20.40.50.5-0.5-0.60.30.60.5-0.10.30.4-0.40.4-0.40.30.30.50.3-0.00.00.0-0.10.50.6
Condit. Reinf. active-inactive response ratio0.30.30.7-0.8-0.80.80.4-0.8-0.5-0.50.7-0.5-0.50.5-0.50.5-0.5-0.5-0.4-0.5-0.70.7-0.40.40.00.0
Condit. Reinf. active responses1.21.52.31.51.5-1.5-1.51.31.51.4-1.01.21.3-1.31.3-1.31.21.21.41.20.8-0.80.7-0.71.01.3
Condit. Reinf. inactive responses3.84.96.92.62.6-2.6-2.42.42.42.4-2.12.22.3-2.32.3-2.32.22.22.32.22.0-1.91.6-1.61.71.8
Incentive salience index mean0.40.51.30.90.9-0.9-1.00.51.10.9-0.10.60.7-0.70.6-0.60.60.60.80.60.00.0-0.1-0.00.61.2
Condit. Reinf. lever presses0.91.33.51.41.4-1.4-1.50.91.61.4-0.51.01.2-1.21.1-1.11.11.11.31.00.5-0.40.3-0.30.71.9
Condit. Reinf. active minus inactive responses0.50.71.00.60.6-0.6-0.90.80.90.9-0.91.00.9-0.91.0-1.01.01.00.71.00.9-0.90.8-0.80.60.9
Condit. Reinf. active-inactive response ratio0.10.20.7-0.8-0.80.80.4-0.6-0.5-0.40.4-0.4-0.40.4-0.40.4-0.4-0.4-0.5-0.4-0.40.4-0.20.1-0.3-0.0
Condit. Reinf. active responses0.81.21.50.90.9-0.9-1.11.21.11.2-1.21.21.2-1.21.2-1.21.21.21.01.21.2-1.20.9-0.90.70.7
Condit. Reinf. inactive responses1.92.93.71.81.8-1.8-1.51.91.51.6-1.91.81.8-1.81.7-1.71.71.71.71.81.9-1.91.5-1.51.30.8
Condit. Reinf. lever presses0.50.71.31.11.1-1.1-1.10.91.11.0-0.60.80.9-0.90.8-0.80.80.80.80.80.4-0.40.2-0.20.41.1
Condit. Reinf. lever reinforcers received0.60.81.10.70.7-0.7-1.01.00.91.0-1.01.01.0-1.01.0-1.01.01.00.71.00.9-0.90.6-0.60.50.7
Conditioned reinforcement - actives0.00.20.70.30.4-0.40.00.3-0.1-0.0-0.60.20.2-0.20.2-0.20.20.20.50.20.7-0.70.8-0.80.40.2
Conditioned reinforcement - inactives0.71.97.01.31.2-1.2-1.00.91.00.9-1.31.11.1-1.11.1-1.11.11.11.21.11.4-1.42.5-2.61.91.4
Conditioned locomotion0.50.71.4-1.0-0.90.91.0-1.2-1.1-1.10.7-0.9-0.90.9-0.90.9-0.9-0.9-1.0-0.9-0.50.50.4-0.5-0.90.4
Patch foraging indifference point 0 sec3.29.012.53.33.3-3.3-3.43.03.53.4-2.83.23.0-3.03.1-3.13.23.23.03.22.5-2.52.2-2.22.32.8
Patch foraging indifference point AUC2.04.86.8-2.5-2.42.42.1-2.3-2.3-2.31.9-2.0-2.42.4-2.32.3-2.2-2.2-2.1-2.2-1.81.8-1.92.0-2.6-1.3
Delay disc. indifference point, 0s delay2.42.84.81.61.5-1.5-1.91.31.91.8-1.31.61.8-1.81.7-1.71.61.61.71.71.5-1.51.6-1.61.42.2
Delay disc. indifference point, 16s delay0.30.41.5-0.1-0.10.10.6-0.3-0.5-0.50.5-0.6-0.60.6-0.60.6-0.5-0.5-0.6-0.5-0.40.4-0.91.0-1.2-0.8
Delay disc. indifference point, 2s delay1.01.15.30.91.0-1.0-1.40.61.41.3-0.51.11.0-1.01.0-1.01.01.01.11.00.6-0.60.8-0.80.42.3
Delay disc. indifference point, 24s delay0.30.51.8-0.5-0.50.50.6-0.8-0.6-0.70.9-0.9-0.70.7-0.70.7-0.8-0.8-0.3-0.8-0.50.5-0.70.8-1.30.3
Delay disc. indifference point, 4s delay1.01.11.8-0.6-0.50.50.8-0.9-0.7-0.81.3-1.1-1.11.1-1.21.2-1.1-1.1-1.1-1.1-1.21.3-1.31.4-1.3-0.2
Delay disc. indifference point, 8s delay0.30.52.20.10.1-0.10.70.0-0.4-0.40.6-0.6-0.60.6-0.70.7-0.7-0.7-1.1-0.6-0.60.6-0.70.7-1.2-1.5
Indifference point function ln k0.72.13.01.71.7-1.7-1.51.71.61.7-1.11.41.6-1.61.6-1.61.51.51.51.41.1-1.10.9-0.81.60.5
Indifference point function log k0.72.13.01.71.7-1.7-1.51.71.61.7-1.11.41.6-1.61.6-1.61.51.51.51.41.1-1.10.9-0.81.60.5
Patch foraging total patch changes 0 sec2.67.611.23.13.1-3.1-3.32.83.33.2-2.52.92.8-2.82.8-2.83.03.02.82.92.2-2.11.8-1.82.02.7
Patch foraging total patch changes 12 sec0.60.92.71.01.1-1.1-1.30.71.21.0-0.91.10.6-0.60.8-0.80.90.90.81.00.7-0.70.6-0.60.11.6
Patch foraging total patch changes 18 sec0.10.20.60.80.8-0.8-0.40.40.40.4-0.50.50.1-0.10.3-0.30.50.50.40.40.4-0.40.2-0.2-0.30.4
Patch foraging total patch changes 24 sec0.41.34.61.41.4-1.4-1.60.91.51.4-0.81.30.8-0.81.0-1.01.21.20.81.10.6-0.60.4-0.40.12.2
Patch foraging total patch changes 6 sec0.20.30.60.70.7-0.7-0.80.50.60.6-0.60.60.2-0.20.4-0.40.50.50.40.50.5-0.50.4-0.50.10.6
Patch foraging time to switch 0 sec0.41.42.61.41.4-1.4-0.91.20.90.9-1.41.11.1-1.11.1-1.11.01.01.11.11.3-1.31.6-1.61.30.7
Patch foraging water rate 0 sec0.00.20.8-0.5-0.40.4-0.1-0.40.20.10.6-0.20.0-0.00.0-0.0-0.0-0.00.0-0.1-0.60.6-0.90.9-0.40.5
Patch foraging water rate 12 sec0.00.20.40.30.3-0.3-0.40.30.50.50.30.10.4-0.40.4-0.40.30.30.50.2-0.20.3-0.60.60.40.4
Patch foraging water rate 18 sec1.73.77.3-1.8-1.61.61.5-1.8-1.4-1.62.4-2.0-1.71.7-1.81.8-2.0-2.0-1.8-1.9-2.42.4-2.72.7-1.9-0.8
Patch foraging water rate 24 sec0.91.23.2-0.7-0.70.71.4-0.6-1.1-1.11.1-1.3-0.90.9-1.11.1-1.1-1.1-0.9-1.0-1.01.0-1.51.6-0.8-1.8
Patch foraging water rate 6 sec0.40.62.4-0.5-0.50.50.0-0.80.1-0.11.2-0.6-0.30.3-0.40.4-0.5-0.5-0.3-0.5-1.21.2-1.61.5-0.80.9
Seeking ratio, delayed vs. immediate footshock2.23.25.31.61.6-1.6-1.71.21.81.8-1.61.81.9-1.91.9-1.91.91.91.91.71.5-1.51.9-1.92.12.3
Distance traveled before self-admin0.10.21.5-0.3-0.30.3-0.2-0.60.2-0.00.6-0.3-0.40.4-0.30.3-0.3-0.3-0.4-0.3-0.70.7-0.50.5-0.61.2
Distance traveled after self-admin0.50.92.3-1.2-1.21.20.3-1.2-0.2-0.51.3-0.8-0.80.8-0.60.6-0.7-0.7-0.6-0.8-1.11.2-1.51.5-1.30.7
Extensor digitorum longus weight5.823.240.9-4.8-4.84.83.3-5.4-3.4-3.95.8-4.6-4.64.6-4.64.6-4.6-4.6-4.7-4.6-5.95.9-6.46.3-5.1-0.6
Bone: elastic displacement1.51.93.61.31.3-1.3-1.71.11.71.5-1.21.51.4-1.41.4-1.41.41.41.51.41.0-1.00.9-0.91.01.9
Bone: elastic work2.22.95.91.81.8-1.8-2.21.52.32.1-1.21.81.8-1.81.8-1.81.81.81.71.81.1-1.00.6-0.60.82.4
Bone: endosteal estimation0.30.71.01.01.0-1.0-1.00.91.00.9-0.80.80.8-0.80.8-0.80.80.80.60.80.7-0.70.5-0.50.20.9
Bone: endosteal perimeter1.02.53.71.51.5-1.5-1.91.41.91.8-1.41.71.7-1.71.7-1.71.71.71.61.71.3-1.31.1-1.11.01.9
Epididymis fat weight0.10.61.31.01.0-1.0-0.71.20.60.7-0.80.60.8-0.80.8-0.80.60.60.80.70.9-0.90.4-0.30.6-0.6
Delta time in closed arm before/after self-admin1.11.12.50.70.7-0.7-0.80.80.70.8-1.21.01.1-1.11.0-1.01.01.00.91.01.2-1.21.6-1.61.30.5
Delta time in open arm before/after self-admin0.10.10.4-0.3-0.30.30.2-0.3-0.3-0.30.3-0.3-0.60.6-0.30.3-0.3-0.3-0.5-0.3-0.40.4-0.30.3-0.30.0
Diff in mean of infusions in LGA sessions0.10.20.50.50.5-0.5-0.60.40.70.5-0.00.30.6-0.60.5-0.50.30.30.60.4-0.10.1-0.50.50.60.2
Delay discount exponential model param0.40.52.20.20.1-0.1-0.50.50.30.5-0.90.70.7-0.70.8-0.80.80.80.90.80.8-0.80.9-0.91.50.0
Extinction: sum of active levers before priming0.40.71.01.01.0-1.0-0.70.90.80.8-0.90.81.0-1.00.8-0.80.80.80.90.80.9-0.90.3-0.30.60.2
Active lever presses in extinction session 60.50.51.1-0.6-0.60.61.0-0.7-1.0-0.90.4-0.8-0.70.7-0.70.7-0.8-0.8-0.6-0.9-0.30.3-0.00.0-0.6-0.9
Bone: final force0.10.10.40.60.6-0.6-0.40.40.40.4-0.00.10.1-0.10.1-0.10.10.1-0.10.2-0.00.0-0.20.2-0.70.4
Bone: final moment0.20.41.21.11.1-1.1-0.80.80.80.7-0.30.40.4-0.40.4-0.40.40.40.20.40.2-0.2-0.10.0-0.40.6
Food consumed during 24 hour testing period0.10.10.60.40.4-0.4-0.2-0.10.20.10.5-0.1-0.10.1-0.10.1-0.1-0.10.1-0.1-0.50.5-0.70.8-0.30.6
Glucose1.62.53.4-1.2-1.21.21.7-1.3-1.7-1.71.5-1.6-1.81.8-1.71.7-1.7-1.7-1.8-1.6-1.41.3-1.41.5-1.8-1.6
Heart weight0.30.51.20.70.7-0.7-0.51.10.40.5-0.80.60.7-0.70.7-0.70.50.50.80.70.8-0.80.5-0.40.9-0.8
Delay discount hyperbolic model param0.30.41.60.10.0-0.0-0.30.50.20.3-0.80.60.6-0.60.6-0.60.60.60.70.60.7-0.70.8-0.81.3-0.3
Intermittent access intake day 1-15 change0.10.30.70.20.2-0.2-0.50.50.40.4-0.60.70.4-0.40.4-0.40.60.60.60.60.8-0.80.8-0.90.60.4
Intermittent access intake escalation0.00.20.60.20.2-0.2-0.50.50.40.3-0.60.60.2-0.20.2-0.20.50.50.40.60.6-0.60.7-0.80.50.2
Intermittent access intake escalation 20.00.00.1-0.3-0.30.3-0.20.1-0.0-0.1-0.10.2-0.10.1-0.10.10.10.10.10.10.1-0.10.2-0.20.20.0
Intermitt. access day 1 inactive lever presses0.00.63.50.30.3-0.3-0.30.30.10.2-0.80.50.4-0.40.4-0.40.50.50.50.50.9-0.91.8-1.91.60.7
Intermitt. access day 15 inactive lever presses0.21.32.1-1.3-1.31.31.3-1.3-1.2-1.21.1-1.1-1.11.1-1.11.1-1.1-1.1-1.2-1.1-1.11.1-1.01.0-0.1-1.4
Intermitt. access escalation Index0.30.81.10.70.7-0.7-0.80.70.80.9-0.90.91.1-1.11.1-1.11.01.01.00.80.9-0.90.9-1.00.80.9
Intermittent access day 1 total infusions0.10.20.8-0.3-0.10.10.5-0.8-0.5-0.60.6-0.6-0.40.4-0.40.4-0.6-0.6-0.1-0.6-0.40.40.0-0.1-0.80.9
Intermittent access day 15 total infusions0.00.10.7-0.2-0.10.10.2-0.2-0.3-0.3-0.2-0.1-0.10.1-0.10.1-0.0-0.00.2-0.00.3-0.30.8-0.80.10.3
Intermittent access terminal intake (last 3 days)0.40.71.5-0.9-0.80.81.0-0.9-1.1-1.20.7-0.9-1.01.0-1.01.0-1.0-1.0-0.8-0.9-0.60.5-0.20.2-0.8-0.5
Intermittent access total infusions0.10.20.5-0.3-0.10.10.6-0.4-0.7-0.7-0.0-0.4-0.30.3-0.30.3-0.4-0.4-0.1-0.40.2-0.20.7-0.7-0.30.0
Intermittent access day 1 locomotion0.30.62.10.60.8-0.8-0.60.40.60.5-0.50.50.7-0.70.7-0.70.60.60.80.50.6-0.61.2-1.20.51.4
Intermittent access day 15 total locomotion0.31.01.5-0.9-0.70.71.1-1.0-1.1-1.21.0-1.2-1.21.2-1.21.2-1.1-1.1-1.1-1.1-0.80.8-0.30.2-0.7-0.6
Intermittent access total locomotion0.10.10.4-0.2-0.00.00.2-0.3-0.3-0.40.2-0.4-0.20.2-0.20.2-0.3-0.3-0.3-0.3-0.10.10.6-0.6-0.00.2
Intermittent access standard deviation0.52.43.3-1.6-1.61.61.3-1.8-1.3-1.41.8-1.5-1.61.6-1.61.6-1.6-1.6-1.4-1.6-1.71.7-1.71.7-1.6-0.4
Left kidney weight0.00.10.30.40.4-0.4-0.40.00.30.20.3-0.2-0.00.0-0.10.1-0.1-0.1-0.4-0.1-0.50.6-0.20.10.10.5
Right kidney weight0.21.43.01.51.5-1.5-1.71.11.51.4-0.71.11.2-1.21.2-1.21.11.10.91.10.5-0.40.8-0.81.41.6
Cocaine induced anxiety0.41.22.21.21.4-1.4-1.41.21.51.3-0.91.11.2-1.21.2-1.21.11.11.01.10.6-0.60.7-0.70.90.8
Post-drug Anxiety4.45.17.62.22.3-2.3-2.32.82.52.5-2.42.52.5-2.52.5-2.52.52.52.02.52.0-2.01.3-1.22.10.1
Baseline Anxiety0.20.41.00.40.3-0.3-0.40.90.40.5-0.90.80.7-0.70.7-0.70.80.80.60.81.0-1.00.10.10.4-0.5
Tail length0.31.52.71.71.6-1.6-1.21.51.21.3-1.11.11.2-1.21.2-1.21.11.11.01.11.0-1.01.0-1.11.20.4
Length with tail0.52.44.11.91.8-1.8-2.01.71.91.9-1.11.51.8-1.81.7-1.71.51.51.61.51.0-0.90.7-0.71.51.3
Length without tail0.10.42.60.30.3-0.3-1.1-0.10.80.60.60.20.2-0.20.2-0.20.10.10.30.1-0.70.7-1.11.0-0.31.6
Times rat made contact with spout0.10.10.2-0.2-0.20.20.4-0.2-0.4-0.40.2-0.3-0.50.5-0.40.4-0.3-0.3-0.3-0.3-0.20.2-0.10.2-0.3-0.1
Lifetime Intake0.20.20.7-0.5-0.30.30.6-0.6-0.8-0.80.2-0.6-0.40.4-0.40.4-0.5-0.5-0.2-0.5-0.10.00.5-0.5-0.40.3
Liver weight, left0.20.32.30.20.2-0.2-0.6-0.50.50.30.9-0.2-0.10.1-0.10.1-0.1-0.1-0.2-0.2-0.91.0-0.60.50.11.5
Liver weight, right2.03.55.7-1.4-1.51.51.6-1.8-1.6-1.72.2-2.0-1.91.9-1.91.9-1.9-1.9-1.9-1.9-2.02.0-2.42.4-2.1-1.1
Locomotor activity1.32.05.31.51.5-1.5-2.31.22.21.9-0.51.41.5-1.51.5-1.51.21.21.61.30.3-0.2-0.20.11.02.0
Locomotor testing distance4.410.715.23.43.3-3.3-3.83.33.93.8-2.83.53.6-3.63.6-3.63.43.43.63.42.6-2.52.1-2.23.02.8
Locomotor testing rearing4.115.020.73.93.9-3.9-4.53.64.64.5-3.34.14.2-4.24.2-4.24.04.04.34.03.1-3.02.6-2.73.73.8
Locomotion in novel chamber0.10.10.50.30.3-0.3-0.10.40.10.1-0.40.10.1-0.10.1-0.10.30.3-0.10.10.3-0.30.6-0.7-0.1-0.4
Locomotion in novel chamber post-restriction0.31.02.7-1.6-1.61.60.5-1.4-0.5-0.81.0-0.6-0.80.8-0.70.7-0.7-0.7-0.9-0.7-1.01.0-1.31.2-1.40.3
Fecal boli incidents, locomotor time 10.71.73.7-0.5-0.40.41.0-0.8-1.0-1.11.5-1.5-1.41.4-1.41.4-1.6-1.6-1.5-1.6-1.51.5-1.51.5-1.9-0.5
Change in fecal boli incidents, locomotor task0.10.11.2-0.2-0.40.40.3-0.0-0.1-0.1-0.40.10.1-0.10.1-0.10.20.20.40.40.2-0.30.3-0.30.9-1.1
Time >=10cm from walls, locomotor time 11.01.22.11.31.3-1.3-1.21.41.11.2-1.31.21.0-1.01.0-1.01.21.20.81.21.0-1.00.7-0.81.30.0
Bouts of movement, locomotor time 10.81.12.7-1.6-1.61.60.8-1.4-0.9-0.81.0-0.9-0.90.9-0.90.9-0.9-0.9-1.1-0.9-1.11.1-0.20.1-0.70.6
Total resting periods, locomotor time 11.72.04.5-2.0-2.12.11.4-1.8-1.4-1.41.4-1.4-1.41.4-1.41.4-1.3-1.3-1.4-1.3-1.41.3-0.50.4-1.10.1
Rest time, locomotor task time 11.11.83.8-1.9-1.91.91.6-1.8-1.5-1.41.1-1.4-1.31.3-1.31.3-1.2-1.2-1.3-1.2-1.11.0-0.50.5-1.4-0.1
Distance moved, locomotor task time 10.61.63.21.71.8-1.8-1.31.81.21.1-1.41.41.2-1.21.2-1.21.21.21.11.31.3-1.30.5-0.51.1-0.4
Vertical activity count, locomotor time 10.21.23.11.41.5-1.5-1.81.21.61.3-0.61.31.0-1.01.0-1.01.11.11.11.00.6-0.5-0.20.10.51.0
Time >=10cm from walls, locomotor time 20.00.10.30.0-0.30.30.2-0.3-0.1-0.20.2-0.2-0.30.3-0.30.3-0.2-0.2-0.1-0.4-0.30.4-0.30.20.0-0.6
Bouts of movement, locomotor time 20.72.23.3-1.8-1.71.71.5-1.6-1.5-1.41.7-1.5-1.31.3-1.31.3-1.3-1.3-1.2-1.6-1.51.5-1.71.8-1.3-1.1
Total resting periods, locomotor time 21.04.25.3-2.3-2.22.22.2-2.1-2.1-2.02.3-2.2-1.91.9-1.91.9-1.9-1.9-1.8-2.2-2.12.0-2.22.3-1.8-1.6
Rest time, locomotor task time 26.310.713.7-3.3-3.13.13.4-3.2-3.3-3.33.2-3.6-3.43.4-3.43.4-3.3-3.3-3.5-3.4-3.13.1-2.93.0-3.7-2.1
Distance moved, locomotor task time 23.85.17.92.82.7-2.7-2.42.32.32.2-2.32.52.3-2.32.3-2.32.32.32.22.22.2-2.21.7-1.72.01.0
Vertical activity count, locomotor time 21.32.94.92.02.0-2.0-2.21.32.12.0-1.21.91.9-1.91.8-1.81.71.71.91.51.3-1.20.9-1.01.02.1
Light reinforcement 10.10.40.80.90.9-0.9-0.10.70.20.4-0.60.50.5-0.50.5-0.50.50.50.70.50.8-0.90.4-0.30.6-0.7
Light reinforcement 20.81.85.9-1.2-1.21.21.9-1.0-1.8-1.61.1-1.5-1.21.2-1.31.3-1.4-1.4-1.1-1.5-0.70.7-1.01.1-0.9-2.4
Bone: marrow area0.30.81.21.11.1-1.1-1.11.01.01.0-0.80.90.9-0.90.9-0.90.90.90.70.90.8-0.80.6-0.60.20.9
Bone: maximum diameter0.20.31.6-0.4-0.40.40.0-0.7-0.1-0.30.7-0.4-0.40.4-0.40.4-0.4-0.4-0.3-0.4-0.60.6-1.01.0-1.31.0
Bone: maximum force0.10.31.30.70.7-0.7-0.70.30.60.50.20.10.2-0.20.2-0.20.20.2-0.10.2-0.20.2-0.70.6-1.21.0
Bone: maximum moment0.30.61.61.21.2-1.2-1.10.71.10.9-0.10.50.5-0.50.5-0.50.50.50.20.50.1-0.0-0.50.4-0.91.2
Mean time between licks in bursts0.74.15.61.91.9-1.9-1.72.31.61.8-2.42.12.0-2.02.0-2.02.12.11.92.12.4-2.42.2-2.12.30.4
Mean num. licks in bursts0.00.00.20.20.2-0.2-0.20.00.10.10.10.0-0.00.0-0.00.00.00.00.10.0-0.20.2-0.30.3-0.10.5
Cd content in liver0.10.20.60.10.2-0.2-0.6-0.30.40.30.60.00.1-0.10.2-0.2-0.1-0.1-0.1-0.1-0.70.7-0.70.60.20.8
Co content in liver3.03.64.5-2.0-2.02.01.5-2.0-1.7-1.82.0-1.9-1.91.9-1.81.8-1.9-1.9-1.7-1.9-2.02.0-2.12.1-2.0-1.0
Cu content in liver1.01.21.7-1.3-1.31.30.9-1.3-1.0-1.01.2-1.0-0.90.9-1.01.0-1.0-1.0-1.2-1.0-1.21.2-1.21.2-0.9-0.4
Fe content in liver1.62.03.71.31.3-1.3-1.11.51.11.2-1.71.51.3-1.31.3-1.31.41.41.41.41.5-1.61.7-1.71.90.1
K content in liver0.20.20.60.00.0-0.00.20.3-0.20.0-0.70.30.4-0.40.3-0.30.40.40.40.30.7-0.70.8-0.80.7-0.6
Mg content in liver0.60.61.10.50.5-0.5-0.30.70.40.6-1.00.80.9-0.90.8-0.80.90.90.90.81.0-1.11.0-1.00.90.2
Mn content in liver1.61.72.51.11.1-1.1-1.11.31.11.2-1.51.31.4-1.41.3-1.31.41.41.51.41.6-1.61.4-1.41.10.8
Na content in liver0.30.41.7-0.1-0.10.1-0.7-0.30.70.50.70.00.0-0.00.0-0.00.10.10.10.1-0.90.9-1.31.3-0.41.1
Rb content in liver0.10.10.9-0.1-0.10.10.30.0-0.3-0.2-0.1-0.1-0.00.0-0.00.0-0.0-0.0-0.1-0.10.0-0.10.2-0.20.6-0.9
Se content in liver5.46.47.92.22.2-2.2-2.82.22.72.8-2.32.72.8-2.82.7-2.72.72.72.82.62.1-2.12.2-2.22.62.8
Sr content in liver0.80.71.50.30.3-0.3-0.90.50.80.9-0.80.90.9-0.90.9-0.90.90.91.00.90.7-0.70.9-0.91.21.2
Zn content in liver1.01.21.51.01.0-1.0-1.10.91.01.1-1.01.21.2-1.21.2-1.21.11.11.21.21.0-1.00.9-1.01.11.1
Bone: minimum diameter0.20.52.21.01.0-1.0-1.10.51.00.8-0.20.50.5-0.50.5-0.50.50.50.40.50.1-0.0-0.20.1-0.41.5
Time in familiar zone, hab. session 10.00.10.20.00.0-0.0-0.00.20.10.2-0.20.20.3-0.30.3-0.30.20.20.40.20.4-0.40.2-0.10.00.1
Time in novel zone, hab. session 12.22.42.9-1.4-1.41.41.4-1.6-1.4-1.61.6-1.6-1.71.7-1.71.7-1.7-1.7-1.6-1.6-1.71.7-1.61.5-1.4-1.2
Total zone transitions, hab. session 10.20.31.50.40.4-0.4-0.80.20.80.7-0.20.50.5-0.50.6-0.60.60.60.70.50.2-0.2-0.20.2-0.31.2
Total locomotion distance, hab. session 11.21.73.71.21.2-1.2-1.61.01.61.5-1.01.41.4-1.41.4-1.41.31.31.61.41.1-1.00.7-0.70.41.9
Locomotion velocity, hab. session 12.94.17.11.91.9-1.9-2.41.72.42.3-1.72.12.2-2.22.2-2.22.12.12.42.11.7-1.71.2-1.21.12.7
Time in familiar zone, hab. session 20.60.72.4-0.9-0.90.91.0-0.5-1.0-0.90.4-0.7-0.90.9-0.90.9-0.8-0.8-1.0-0.7-0.40.4-0.40.4-0.5-1.5
Time in novel zone, hab. session 20.40.42.10.70.7-0.7-0.80.30.80.7-0.30.60.7-0.70.7-0.70.60.60.80.60.3-0.30.3-0.30.31.4
Total zone transitions, hab. session 20.30.42.60.10.1-0.1-0.9-0.11.00.80.10.50.7-0.70.6-0.60.60.60.70.5-0.10.2-0.50.4-0.11.6
Total locomotion distance, hab. session 20.40.62.60.40.4-0.4-0.90.21.00.9-0.30.70.9-0.90.9-0.90.80.81.00.70.4-0.40.1-0.10.21.6
Locomotion velocity, hab. session 20.40.63.60.40.4-0.4-1.00.11.00.9-0.20.70.9-0.90.9-0.90.80.81.00.70.2-0.2-0.10.00.01.9
Novel to familiar place preference ratio0.60.81.81.31.3-1.3-0.91.00.90.9-0.70.80.8-0.80.8-0.80.70.70.70.80.7-0.70.6-0.60.30.9
Novelty place preference0.81.02.11.41.4-1.4-1.11.11.01.0-0.90.91.0-1.00.9-0.90.90.90.90.90.9-0.80.8-0.80.60.9
Time in novel zone, NPP test0.80.91.71.31.3-1.3-1.11.01.11.1-0.80.91.0-1.00.9-0.90.90.90.90.90.8-0.70.7-0.70.61.0
Total zone transitions, NPP test1.72.63.61.21.2-1.2-1.81.31.91.8-1.41.81.9-1.91.8-1.81.81.81.91.81.4-1.41.0-0.91.11.9
Total locomotion distance, NPP test5.98.310.32.62.6-2.6-2.82.72.82.9-3.03.03.2-3.23.1-3.13.03.03.23.02.9-2.92.7-2.72.52.4
Locomotion velocity, NPP test4.76.68.12.42.4-2.4-2.42.42.52.6-2.72.72.8-2.82.8-2.82.72.72.82.72.7-2.72.5-2.52.12.2
Intraocular pressure1.42.33.21.41.3-1.3-1.31.41.41.4-1.61.71.6-1.61.6-1.61.61.61.61.61.6-1.61.5-1.51.80.4
Delta distance traveled before/after self-admin0.70.81.7-1.2-1.21.20.8-1.0-0.7-0.71.0-0.8-0.70.7-0.70.7-0.8-0.8-0.4-0.8-0.80.8-1.31.3-0.8-0.4
Delta ambulatory time before/after self-admin0.40.81.6-1.2-1.21.20.6-1.0-0.6-0.71.1-0.8-0.60.6-0.70.7-0.8-0.8-0.3-0.8-0.90.9-1.31.3-0.9-0.1
Parametrial fat weight1.94.66.82.32.3-2.3-1.82.61.71.9-2.52.12.1-2.12.1-2.12.12.12.02.12.6-2.62.3-2.31.70.7
Pavlov. Cond. lever latency0.10.10.5-0.7-0.70.70.5-0.3-0.5-0.5-0.1-0.1-0.30.3-0.30.3-0.2-0.2-0.5-0.10.1-0.10.3-0.2-0.2-0.5
Pavlov. Cond. magazine entry latency0.00.00.30.30.3-0.3-0.00.30.10.10.10.00.1-0.10.1-0.1-0.0-0.00.20.0-0.10.1-0.30.30.4-0.5
Pavlov. Cond. change in total contacts0.30.31.50.20.2-0.2-0.4-0.40.40.20.8-0.3-0.20.2-0.10.1-0.3-0.30.0-0.3-0.80.9-1.21.1-0.81.2
Pavlov. Cond. index score0.10.10.50.30.3-0.3-0.1-0.00.20.10.5-0.2-0.00.0-0.00.0-0.2-0.20.1-0.2-0.50.5-0.70.7-0.10.1
Pavlov. Cond. latency score0.10.10.30.50.5-0.5-0.30.20.40.30.30.00.2-0.20.2-0.20.00.00.30.0-0.30.3-0.50.50.10.2
Pavlov. Cond. lever contacts0.10.10.40.60.6-0.6-0.30.30.40.40.10.10.3-0.30.2-0.20.10.10.40.1-0.10.1-0.30.30.20.3
Pavlov. Cond. magazine entry number0.30.41.30.30.3-0.3-0.30.50.30.3-0.90.60.5-0.50.5-0.50.60.60.40.60.9-0.91.2-1.20.40.4
Pavlov. Cond. intertrial magazine entries1.51.82.41.61.6-1.6-1.61.31.51.4-1.21.41.3-1.31.3-1.31.31.31.31.41.1-1.10.9-0.91.01.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.10.1-0.1-0.0-0.20.10.00.7-0.3-0.20.2-0.20.2-0.3-0.3-0.0-0.3-0.70.7-0.90.9-0.20.1
Pavlov. Cond. response bias0.30.41.2-0.2-0.20.20.4-0.5-0.3-0.40.9-0.6-0.60.6-0.60.6-0.7-0.7-0.4-0.6-0.90.9-1.11.1-0.5-0.5
Pavlov. Cond. lever latency0.20.21.0-0.2-0.20.20.50.1-0.4-0.2-0.50.10.0-0.00.1-0.10.10.10.10.10.8-0.81.0-1.00.4-0.8
Pavlov. Cond. magazine entry latency0.10.10.60.60.6-0.6-0.50.20.50.30.00.20.2-0.20.1-0.10.20.20.30.2-0.10.1-0.40.4-0.10.8
Pavlov. Cond. change in total contacts0.41.14.5-0.5-0.50.50.1-0.8-0.2-0.51.3-0.8-0.80.8-0.80.8-0.8-0.8-0.9-0.8-1.61.6-2.12.1-1.10.1
Pavlov. Cond. index score0.10.21.10.20.2-0.2-0.5-0.30.40.20.6-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.80.8-1.11.1-0.30.9
Pavlov. Cond. latency score0.10.20.90.40.4-0.4-0.70.00.60.40.30.10.1-0.10.1-0.10.10.10.10.1-0.50.6-0.80.80.01.0
Pavlov. Cond. lever contacts0.20.20.90.30.3-0.3-0.5-0.10.50.30.5-0.1-0.00.0-0.00.0-0.1-0.1-0.1-0.1-0.70.8-1.00.9-0.40.9
Pavlov. Cond. magazine entry number0.20.31.4-0.7-0.70.70.8-0.3-0.7-0.60.3-0.5-0.50.5-0.50.5-0.5-0.5-0.6-0.5-0.20.2-0.0-0.0-0.0-1.2
Pavlov. Cond. intertrial magazine entries3.57.712.22.52.5-2.5-2.13.02.12.5-3.22.82.8-2.82.8-2.82.82.82.82.83.3-3.33.5-3.52.80.9
Pavlov. Cond. lever-magazine prob. diff.0.20.31.40.00.0-0.0-0.3-0.40.30.00.7-0.2-0.20.2-0.30.3-0.2-0.2-0.2-0.2-0.90.9-1.21.2-0.50.9
Pavlov. Cond. response bias0.20.21.20.30.3-0.3-0.6-0.20.60.30.50.00.0-0.00.0-0.0-0.0-0.0-0.00.0-0.70.7-0.90.9-0.41.1
Time in closed arm before self-admin0.20.40.9-0.6-0.60.60.5-0.4-0.5-0.50.8-0.5-0.60.6-0.50.5-0.5-0.5-0.4-0.5-0.70.7-0.91.0-0.2-0.6
Time in closed arm after self-admin0.50.51.30.60.6-0.6-0.50.70.60.6-0.60.70.9-0.90.7-0.70.70.71.00.60.8-0.80.9-0.91.20.4
Time in open arm before self-admin0.91.11.50.90.9-0.9-1.10.91.11.2-1.01.01.2-1.21.1-1.11.21.21.00.91.1-1.01.2-1.20.71.2
Time in open arm after self-admin0.00.00.1-0.0-0.00.0-0.10.00.10.1-0.20.10.0-0.00.2-0.20.10.1-0.20.10.1-0.10.3-0.30.10.2
Bone: periosteal estimation0.20.51.21.01.0-1.0-0.90.70.90.8-0.50.60.6-0.60.6-0.60.60.60.40.60.5-0.40.1-0.2-0.41.1
Bone: periosteal perimeter0.61.22.71.11.1-1.1-1.40.91.41.3-0.91.11.2-1.21.2-1.21.21.21.21.20.9-0.80.6-0.60.41.7
Bone: post-yield work1.42.57.7-1.0-1.01.01.8-1.1-1.7-1.71.3-1.7-1.71.7-1.71.7-1.7-1.7-1.7-1.7-1.00.9-1.41.5-2.8-1.5
Progressive ratio test 1 active lever presses0.81.52.5-1.1-0.90.91.6-1.3-1.5-1.51.2-1.5-1.31.3-1.31.3-1.4-1.4-1.1-1.4-0.90.9-0.70.7-1.4-0.6
Progressive ratio test 1 breakpoint0.91.52.5-1.1-0.90.91.6-1.4-1.5-1.51.3-1.5-1.31.3-1.31.3-1.4-1.4-1.1-1.4-1.01.0-0.80.8-1.5-0.5
Progressive ratio test 1 inactive lever presses0.20.51.10.70.7-0.7-0.00.50.10.3-0.70.40.7-0.70.7-0.70.50.51.00.51.0-1.00.8-0.81.1-0.6
Progressive ratio test 2 active lever presses0.81.11.8-0.8-0.70.71.2-1.3-1.2-1.31.2-1.4-1.21.2-1.21.2-1.2-1.2-0.8-1.3-1.01.0-0.40.4-0.9-0.2
Progressive ratio test 2 breakpoint0.81.01.6-0.8-0.60.61.1-1.3-1.0-1.21.2-1.3-1.11.1-1.11.1-1.2-1.2-0.8-1.2-1.01.0-0.40.4-0.8-0.1
Progressive ratio test 2 inactive lever presses0.10.30.9-0.3-0.20.21.0-0.7-0.8-0.90.4-0.8-0.60.6-0.60.6-0.6-0.6-0.3-0.7-0.20.20.4-0.50.1-0.6
Incentive Sensitization - Responses0.00.10.70.10.1-0.1-0.1-0.50.1-0.10.6-0.3-0.30.3-0.30.3-0.3-0.3-0.1-0.4-0.60.60.1-0.20.00.8
Incentive Sensitization - Breakpoint0.00.10.70.10.1-0.1-0.2-0.50.2-0.00.5-0.2-0.20.2-0.20.2-0.2-0.2-0.0-0.3-0.50.60.1-0.20.10.8
Sum of active levers in priming session hrs 5-60.20.11.10.10.1-0.10.60.2-0.6-0.4-0.2-0.3-0.10.1-0.20.2-0.3-0.3-0.0-0.30.3-0.40.5-0.50.2-1.0
Progressive ratio0.30.81.4-1.0-0.90.90.5-1.1-0.4-0.51.1-0.9-0.90.9-0.90.9-0.5-0.5-0.5-0.7-1.11.2-1.21.1-0.70.8
Food seeking constrained by brief footshock2.83.57.6-2.8-2.82.82.3-2.3-2.3-2.01.7-2.0-1.71.7-1.71.7-1.7-1.7-1.6-1.8-1.51.4-1.21.2-1.0-1.1
Seeking ratio, punishment vs. effort0.30.61.6-1.1-1.11.11.1-0.7-1.1-0.90.4-0.6-0.60.6-0.50.5-0.8-0.8-0.9-0.7-0.30.3-0.00.1-0.3-1.2
Retroperitoneal fat weight0.41.62.61.51.4-1.4-0.91.50.91.1-1.41.11.3-1.31.3-1.31.11.11.31.11.6-1.61.5-1.41.10.2
Reaction time number correct0.00.10.7-0.5-0.40.40.6-0.2-0.4-0.30.2-0.3-0.20.2-0.10.1-0.3-0.3-0.1-0.2-0.10.1-0.30.30.1-0.8
Reaction time mean minus median0.00.30.50.60.6-0.6-0.70.50.70.6-0.40.60.6-0.60.5-0.50.50.50.40.50.2-0.2-0.10.10.60.0
Reaction time mean minus median AUC0.00.10.50.50.5-0.5-0.40.30.30.4-0.20.40.4-0.40.4-0.40.30.30.50.30.1-0.10.00.00.7-0.1
Reaction time num false alarms0.40.71.10.70.8-0.8-1.00.81.01.0-0.81.00.9-0.90.9-0.90.90.91.00.90.6-0.60.6-0.60.50.7
Reaction time num false alarms AUC0.10.20.40.40.5-0.5-0.60.40.70.6-0.30.50.4-0.40.4-0.40.40.40.60.40.1-0.10.0-0.1-0.00.4
Reaction time trials correct on left0.00.10.7-0.5-0.40.40.6-0.2-0.4-0.30.2-0.3-0.20.2-0.10.1-0.3-0.3-0.1-0.2-0.10.1-0.30.30.1-0.8
Reaction time trials on left0.00.10.8-0.4-0.40.40.6-0.1-0.4-0.30.1-0.2-0.10.1-0.10.1-0.2-0.2-0.0-0.2-0.10.0-0.20.20.1-0.9
Reaction time mean0.00.10.3-0.2-0.30.30.1-0.2-0.2-0.20.3-0.2-0.20.2-0.30.3-0.3-0.3-0.3-0.2-0.40.4-0.50.60.2-0.5
Reaction time mean AUC0.00.10.3-0.1-0.20.2-0.1-0.1-0.0-0.10.2-0.1-0.10.1-0.20.2-0.2-0.2-0.2-0.1-0.40.4-0.60.60.2-0.2
Median of all reaction times0.20.30.4-0.5-0.60.60.4-0.5-0.5-0.50.5-0.5-0.50.5-0.60.6-0.6-0.6-0.6-0.5-0.70.7-0.70.7-0.1-0.5
Reaction time omissions1.21.92.81.61.6-1.6-0.91.70.91.2-1.61.21.4-1.41.4-1.41.41.41.11.31.5-1.51.6-1.61.6-0.1
Reaction time false alarm rate0.10.20.40.40.5-0.5-0.60.40.60.5-0.30.50.4-0.40.3-0.30.40.40.40.40.2-0.20.2-0.3-0.10.5
Reaction time premature initiation rate0.60.92.2-1.5-1.51.50.6-1.1-0.7-0.81.0-0.8-0.80.8-0.70.7-0.9-0.9-1.0-0.8-1.11.1-1.01.0-0.8-0.2
Reaction time premature initiations0.41.32.9-1.7-1.71.71.0-1.3-1.0-1.01.1-1.0-0.90.9-0.80.8-1.1-1.1-1.0-1.0-1.11.1-1.21.2-0.8-0.7
Std. dev. reaction times0.00.00.40.10.1-0.1-0.00.1-0.0-0.0-0.00.00.1-0.1-0.00.0-0.0-0.0-0.2-0.0-0.20.2-0.40.40.2-0.7
Reaction time trials completed0.00.10.8-0.4-0.40.40.6-0.1-0.4-0.30.1-0.2-0.10.1-0.10.1-0.2-0.2-0.0-0.2-0.10.0-0.20.20.1-0.9
Reaction time trials AUC0.00.10.7-0.4-0.30.30.5-0.1-0.3-0.30.1-0.2-0.10.1-0.10.1-0.2-0.20.0-0.1-0.00.0-0.20.20.2-0.8
Run reversals in cocaine runway, females0.20.21.4-0.00.0-0.0-0.10.10.10.1-0.50.20.3-0.30.3-0.30.30.30.10.20.5-0.51.1-1.20.00.7
Run reversals in cocaine runway, males4.95.49.4-2.3-2.32.31.7-2.6-1.6-2.02.7-2.2-2.12.1-2.12.1-2.3-2.3-2.4-2.1-2.72.8-3.13.0-2.7-0.9
Latency to leave start box in cocaine runway0.60.92.4-1.4-1.51.50.8-1.5-0.7-0.71.2-1.0-0.60.6-0.70.7-0.7-0.7-0.4-0.8-1.01.0-0.80.8-0.40.4
Latency to leave start box in cocaine runway, F1.82.24.7-1.8-1.91.91.2-2.2-1.1-1.31.9-1.5-1.31.3-1.41.4-1.4-1.4-1.0-1.4-1.71.8-1.61.5-1.0-0.0
Latency to leave start box in cocaine runway, M0.20.20.50.10.1-0.1-0.20.20.30.5-0.30.20.6-0.60.6-0.60.60.60.50.50.3-0.30.6-0.50.70.7
Std. dev. time between licks in bursts5.610.512.13.33.3-3.3-3.43.43.33.4-3.33.53.3-3.33.4-3.43.53.53.23.53.2-3.12.8-2.73.02.2
Total sessions with >9 infusions0.10.10.3-0.3-0.20.20.3-0.5-0.5-0.50.2-0.4-0.30.3-0.30.3-0.3-0.3-0.1-0.3-0.10.10.3-0.3-0.10.6
Short access day 1 total inactive lever presses1.52.94.1-1.7-1.71.71.4-1.7-1.6-1.81.7-1.7-1.91.9-1.91.9-1.8-1.8-2.0-1.8-1.81.8-1.21.2-1.9-0.1
Short access day 10 total inactive lever presses0.00.00.10.00.0-0.0-0.20.20.10.2-0.30.30.1-0.10.1-0.10.20.20.10.20.3-0.30.3-0.30.20.3
Short access day 1 total infusions0.51.01.7-1.1-1.01.01.1-1.2-1.2-1.30.8-1.2-1.11.1-1.11.1-1.0-1.0-0.7-1.1-0.80.8-0.10.1-0.90.0
Short access day 10 total infusions0.20.31.7-0.4-0.30.30.2-1.0-0.2-0.40.8-0.6-0.40.4-0.40.4-0.5-0.5-0.3-0.5-0.70.7-0.30.2-1.01.3
Short access total infusions0.30.51.0-0.7-0.50.50.5-1.0-0.6-0.80.8-0.8-0.70.7-0.70.7-0.7-0.7-0.4-0.8-0.70.7-0.10.1-0.80.9
Short access day 1 locomotion0.10.22.1-0.2-0.20.2-0.1-0.8-0.1-0.30.8-0.5-0.30.3-0.30.3-0.4-0.4-0.2-0.4-0.60.6-0.30.2-0.41.4
Short access day 10 total locomotion0.00.20.80.20.3-0.3-0.40.20.30.3-0.20.20.3-0.30.3-0.30.20.20.40.20.2-0.20.7-0.80.60.9
Short access total locomotion0.10.11.90.10.2-0.2-0.4-0.20.20.10.2-0.10.1-0.10.1-0.1-0.0-0.00.1-0.0-0.20.20.2-0.30.01.4
One hour access (0.3 mA shock)0.20.22.20.30.4-0.4-0.1-0.3-0.1-0.30.0-0.2-0.10.1-0.10.1-0.2-0.20.0-0.10.3-0.30.7-0.7-0.51.5
Compulsive drug intake1.72.53.51.71.6-1.6-1.41.31.31.4-1.71.51.6-1.61.6-1.61.51.51.31.51.8-1.81.8-1.91.31.7
One hour access (shock baseline)0.20.40.8-0.8-0.60.60.6-0.9-0.7-0.90.6-0.7-0.70.7-0.70.7-0.7-0.7-0.5-0.7-0.50.50.00.0-0.80.5
Social response proportion0.40.42.2-0.8-0.90.91.1-0.5-1.1-0.80.3-0.6-0.40.4-0.40.4-0.5-0.5-0.4-0.7-0.20.1-0.00.10.3-1.5
Social responses2.83.76.21.61.4-1.4-1.22.11.41.7-2.21.92.2-2.22.1-2.12.02.02.32.02.3-2.31.9-1.72.5-0.0
Social time1.01.62.21.41.4-1.4-1.51.11.41.4-1.11.31.2-1.21.2-1.21.21.21.51.31.0-1.01.1-1.21.41.3
Soleus weight0.72.02.8-1.5-1.51.51.3-1.7-1.3-1.41.5-1.4-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.41.4-1.31.2-1.6-0.3
Bone: stiffness0.20.41.1-0.5-0.50.50.3-0.6-0.3-0.40.7-0.6-0.60.6-0.60.6-0.6-0.6-0.8-0.5-0.80.8-0.90.8-1.1-0.0
Tibialis anterior weight3.612.223.3-3.4-3.43.42.1-4.0-2.2-2.74.3-3.3-3.23.2-3.23.2-3.3-3.3-3.4-3.2-4.44.5-4.84.7-3.9-0.1
Time to tail flick, vehicle, before self-admin0.10.10.30.60.5-0.5-0.20.50.20.3-0.40.30.2-0.20.3-0.30.40.40.30.20.4-0.40.00.10.1-0.4
Time to tail flick, vehicle, after self-admin1.83.65.6-2.2-2.22.21.8-1.9-1.9-1.81.8-1.8-2.12.1-2.02.0-1.7-1.7-2.4-1.8-1.81.8-1.71.6-1.4-1.6
Time to tail flick, test, before self-admin1.71.93.11.51.5-1.5-1.21.81.21.4-1.71.61.3-1.31.5-1.51.51.51.21.61.6-1.61.0-0.91.0-0.2
Time to tail flick, test, after self-admin1.01.15.40.70.7-0.70.21.6-0.10.4-1.40.80.6-0.60.8-0.80.90.90.70.81.5-1.60.9-0.71.3-2.3
Delta time to tail flick, vehicle, before/after SA2.12.35.1-1.4-1.41.41.7-1.1-1.7-1.71.2-1.5-1.71.7-1.61.6-1.5-1.5-1.9-1.5-1.31.3-1.21.2-1.0-2.3
Delta time to tail flick, test, before/after SA0.60.74.2-0.9-0.90.91.4-0.3-1.4-1.00.3-0.9-0.80.8-0.80.8-0.6-0.6-0.6-0.8-0.10.1-0.00.10.2-2.0
Tibia length2.77.410.53.23.2-3.2-3.22.93.23.1-2.42.82.8-2.82.8-2.82.82.82.62.82.0-2.01.9-1.92.62.4
Ambulatory time before self-admin0.10.20.6-0.3-0.30.3-0.1-0.50.1-0.10.6-0.3-0.40.4-0.30.3-0.3-0.3-0.5-0.4-0.60.7-0.70.7-0.80.7
Ambulatory time after self-admin1.32.05.1-1.7-1.71.70.5-1.6-0.5-0.81.9-1.2-1.11.1-1.11.1-1.2-1.2-0.9-1.3-1.71.7-2.22.3-1.80.5
Bone: tissue strength0.30.30.80.90.9-0.9-0.70.80.70.6-0.60.60.5-0.50.5-0.50.50.50.40.60.5-0.50.2-0.2-0.00.4
Total heroin consumption1.61.82.9-0.9-0.90.90.8-1.6-1.0-1.11.7-1.5-1.61.6-1.51.5-1.5-1.5-1.6-1.5-1.71.7-1.11.0-1.70.5
Bone: trabecular number1.52.83.81.61.6-1.6-1.31.81.41.5-1.91.71.7-1.71.7-1.71.71.71.71.61.9-2.02.0-1.91.80.6
Bone: trabecular spacing1.42.03.1-1.5-1.51.51.0-1.7-1.0-1.21.6-1.3-1.41.4-1.41.4-1.4-1.4-1.3-1.3-1.61.6-1.71.7-1.8-0.2
Bone: trabecular thickness0.50.71.31.21.2-1.2-0.91.10.90.9-0.80.80.8-0.80.8-0.80.80.80.80.80.8-0.80.5-0.50.30.4
Bone: trabecular tissue density0.50.81.6-0.4-0.40.40.6-0.7-0.6-0.81.0-0.9-1.01.0-1.01.0-1.0-1.0-1.1-1.0-1.21.3-1.21.1-0.9-0.5
Water consumed over 24 hours0.30.61.3-0.8-0.80.80.3-1.1-0.4-0.41.1-0.6-0.70.7-0.60.6-0.6-0.6-0.6-0.6-1.11.1-1.11.1-0.90.7
Number of responses in last shaping day0.70.92.5-0.5-0.40.40.5-0.9-0.6-0.81.2-1.0-0.90.9-0.90.9-0.9-0.9-0.8-0.9-1.21.2-1.61.6-1.20.1