Hub : Genes

Ccdc25

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Ccdc25 0.3 0.14 1.0e-04 0.14 0.08 0.11 0.12 2.6e-04 6.9e-03 1.7e-03 1.1e-03
2 IC isoform ratio NM_001108382.1 0.08 0.06 2.2e-03 0.06 0.04 0.05 0.04 2.3e-03 1.1e-02 3.0e-03 1.3e-02
3 IC isoform ratio XM_063274429.1 0.08 0.06 1.9e-03 0.06 0.04 0.05 0.03 2.1e-03 1.2e-02 3.0e-03 1.7e-02
4 Liver gene expression Ccdc25 0.37 0.15 0.0e+00 0.28 0.3 0.3 0.3 1.8e-31 3.9e-33 4.6e-33 1.4e-33
5 pVTA gene expression Ccdc25 0.41 0.12 0.0e+00 0.39 0.28 0.39 0.11 8.7e-33 1.0e-22 1.9e-33 3.0e-09
6 Brain mRNA stability Ccdc25 0.03 0.03 2.2e-03 0.02 0.03 0.02 0.02 3.2e-03 4.5e-04 4.3e-03 4.3e-03
7 IL gene expression Ccdc25 0.29 0.14 6.8e-05 0.17 0.13 0.18 0.21 7.7e-05 6.2e-04 3.6e-05 9.7e-06
8 NAcc gene expression Ccdc25 0.22 0.08 0.0e+00 0.28 0.12 0.3 0.1 3.1e-43 2.5e-17 2.4e-45 1.9e-14
9 Brain gene expression Ccdc25 0.23 0.1 0.0e+00 0.31 0.29 0.29 0.3 1.6e-29 4.1e-27 2.5e-27 6.2e-28
10 BLA isoform ratio NM_001108382.1 0.11 0.07 3.9e-04 0.05 0.04 0.02 0.03 1.5e-03 5.5e-03 2.3e-02 9.6e-03
11 BLA isoform ratio XM_063274429.1 0.12 0.07 2.0e-04 0.06 0.04 0.02 0.04 6.3e-04 3.3e-03 3.9e-02 5.7e-03
12 Brain isoform ratio NM_001108382.1 0.06 0.03 3.7e-06 0.07 0.06 0.06 0.07 3.5e-07 1.8e-06 1.9e-06 9.4e-07
13 Brain isoform ratio XM_063274429.1 0.05 0.03 7.1e-06 0.07 0.06 0.06 0.06 7.0e-07 4.4e-06 6.6e-06 1.7e-06
14 BLA gene expression Ccdc25 0.31 0.11 2.8e-14 0.21 0.2 0.2 0.21 3.2e-11 6.8e-11 9.9e-11 3.8e-11
15 PL gene expression Ccdc25 0.18 0.08 0.0e+00 0.22 0.22 0.2 0.21 1.8e-23 4.6e-23 5.7e-21 1.5e-22
16 IC gene expression Ccdc25 0.24 0.1 1.6e-10 0.24 0.11 0.2 0.13 1.4e-10 2.1e-05 7.7e-09 4.3e-06
17 Adipose gene expression Ccdc25 0.11 0.07 2.3e-09 0.06 0.06 0.05 0.05 3.4e-07 6.4e-07 1.5e-06 2.6e-06
18 PL isoform ratio XM_063274429.1 0.04 0.03 5.8e-06 0.04 0.04 0.01 0.04 5.0e-05 1.1e-05 1.2e-02 3.5e-05
19 PL isoform ratio NM_001108382.1 0.04 0.03 4.1e-06 0.04 0.05 0.02 0.04 3.1e-05 8.8e-06 6.9e-03 4.0e-05
20 NAcc isoform ratio NM_001108382.1 0.04 0.03 8.8e-07 0.04 0.04 0.04 0.03 5.2e-07 1.4e-06 2.9e-07 5.6e-06
21 NAcc isoform ratio XM_063274429.1 0.04 0.03 1.0e-06 0.04 0.04 0.05 0.03 4.2e-06 1.2e-06 1.5e-07 7.4e-06
22 OFC gene expression Ccdc25 0.36 0.17 2.9e-04 0.04 0.07 0.08 0.05 3.6e-02 9.7e-03 5.2e-03 2.8e-02
23 BLA intron excision ratio chr15_44239899_44247171 0.16 0.11 4.7e-03 0.01 0.02 0.04 0.03 4.9e-02 1.9e-02 3.1e-03 1.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.32.23.1-1.4-1.41.4-1.3-1.61.3-1.6-1.4-1.5-1.61.6-1.61.6-1.6-1.6-1.5-1.51.7-1.7-1.51.5-1.2-0.7
Area under the delay curve0.10.21.2-0.2-0.20.20.20.1-0.00.50.10.30.3-0.30.4-0.40.40.40.50.4-0.40.40.6-0.61.1-0.1
BMI with tail0.20.81.11.00.9-0.91.00.9-0.90.81.01.10.9-0.90.9-0.90.90.90.90.9-0.80.80.6-0.60.80.7
BMI without tail0.51.43.21.11.1-1.11.70.9-1.50.91.41.51.2-1.21.2-1.21.21.21.21.2-0.80.80.5-0.50.81.8
Body weight0.00.20.60.00.0-0.00.00.30.00.70.10.50.2-0.20.3-0.30.40.40.30.4-0.70.80.8-0.70.5-0.1
Weight adjusted by age0.10.20.6-0.1-0.10.1-0.7-0.00.60.4-0.4-0.2-0.20.2-0.20.2-0.1-0.10.2-0.1-0.70.70.7-0.6-0.1-0.4
Bone surface1.52.63.4-1.8-1.81.8-1.7-1.71.6-1.6-1.7-1.6-1.71.7-1.71.7-1.7-1.7-1.6-1.61.6-1.6-1.41.4-1.1-1.1
Bone volume1.52.63.4-1.8-1.81.8-1.6-1.81.6-1.7-1.6-1.6-1.71.7-1.71.7-1.7-1.7-1.6-1.61.7-1.7-1.41.4-0.9-1.0
Breakpoint value in progressive ratio session0.00.00.2-0.1-0.10.1-0.2-0.10.2-0.2-0.2-0.2-0.20.2-0.20.2-0.2-0.20.2-0.10.1-0.1-0.30.30.3-0.5
Number of licking bursts0.10.10.40.40.4-0.40.60.3-0.60.10.50.40.4-0.40.4-0.40.40.40.30.4-0.00.0-0.10.10.20.6
Context. condit. distance diff. score1.61.95.31.61.6-1.62.31.1-2.20.61.91.41.3-1.31.3-1.31.31.31.31.4-0.30.3-0.0-0.10.62.2
Locomotion velocity, session 10.80.91.9-0.6-0.60.6-1.0-0.71.1-0.8-1.0-1.0-1.11.1-1.11.1-1.0-1.0-1.1-1.00.8-0.8-0.50.5-0.5-1.4
Locomotion distance, session 12.32.97.6-1.2-1.21.2-2.1-1.12.1-1.4-2.0-1.8-2.02.0-1.91.9-1.9-1.9-2.0-1.81.2-1.2-0.80.8-0.9-2.8
Locomotion velocity, session 21.11.33.8-1.0-1.01.0-1.4-0.81.4-0.9-1.3-1.2-1.31.3-1.31.3-1.2-1.2-1.2-1.20.8-0.8-0.70.7-0.5-1.9
Locomotion distance, session 23.34.69.1-1.7-1.71.7-2.6-1.62.7-1.8-2.5-2.3-2.52.5-2.52.5-2.4-2.4-2.4-2.31.7-1.6-1.31.3-1.3-3.0
Locomotion velocity, session 32.02.33.01.61.6-1.61.61.6-1.51.61.51.51.4-1.41.4-1.41.61.61.31.5-1.61.61.7-1.71.21.2
Locomotion distance, session 30.80.91.41.11.1-1.11.10.8-1.00.81.00.90.9-0.90.9-0.90.90.90.90.9-0.70.71.0-1.10.81.2
Stereotopy head waving bouts, day 30.10.10.30.40.4-0.4-0.20.40.20.2-0.1-0.0-0.10.1-0.10.10.00.0-0.2-0.0-0.30.30.10.0-0.5-0.6
Stereotopy head waving duration, day 30.60.71.61.01.0-1.00.31.2-0.41.10.50.80.7-0.70.7-0.70.80.80.50.8-1.31.31.2-1.10.6-0.4
Locomotion velocity, session 71.11.35.80.90.9-0.92.00.5-1.90.01.51.01.1-1.11.1-1.11.01.01.01.00.3-0.3-0.70.50.22.4
Locomotion distance, session 70.50.73.6-0.2-0.20.20.9-0.7-0.8-1.20.5-0.10.1-0.10.1-0.1-0.0-0.0-0.0-0.11.3-1.4-1.51.3-0.31.9
Stereotopy head waving bouts, day 70.30.41.00.70.7-0.7-0.10.90.10.90.10.40.2-0.20.3-0.30.40.40.20.4-1.01.01.0-0.90.3-0.9
Stereotopy head waving duration, day 71.21.53.21.41.4-1.40.51.5-0.61.70.81.11.0-1.01.0-1.01.11.10.91.1-1.81.81.8-1.70.7-0.1
Locomotion velocity, session 80.50.61.41.21.2-1.20.91.0-0.80.80.70.70.6-0.60.6-0.60.60.60.60.7-0.60.60.5-0.60.70.1
Locomotion distance, session 80.20.20.60.10.1-0.1-0.0-0.10.1-0.6-0.2-0.5-0.60.6-0.60.6-0.6-0.6-0.6-0.50.7-0.8-0.70.6-0.3-0.5
Degree of sensitization distance1.61.65.5-1.3-1.31.3-0.1-1.50.1-1.9-0.4-0.9-0.80.8-0.70.7-0.8-0.8-0.9-0.92.0-2.0-2.42.3-1.00.9
Degree of sensitization stereotypy0.70.71.70.90.9-0.90.41.1-0.41.20.60.80.7-0.70.7-0.70.80.80.60.8-1.21.21.3-1.30.8-0.2
Conditioned locomotion0.10.20.90.60.6-0.60.60.2-0.6-0.10.50.20.3-0.30.2-0.20.20.20.20.20.1-0.20.0-0.10.00.9
Cocaine response after cond. corrected1.51.83.01.51.5-1.51.71.2-1.71.01.61.41.4-1.41.3-1.31.41.41.41.4-0.70.70.8-0.91.31.6
Cocaine response after cond. not corrected0.60.71.31.01.0-1.01.10.8-1.10.61.10.80.8-0.80.8-0.80.80.80.90.8-0.30.30.3-0.41.00.9
Cocaine response before conditioning2.22.63.4-1.8-1.81.8-1.8-1.51.8-1.5-1.7-1.6-1.71.7-1.61.6-1.7-1.7-1.6-1.61.3-1.3-1.41.4-1.3-1.7
Saline control response1.01.32.0-1.3-1.31.3-1.4-1.21.4-0.9-1.4-1.1-1.21.2-1.21.2-1.2-1.2-1.3-1.10.7-0.7-0.50.5-1.0-1.2
Bone: connectivity density2.13.35.7-1.4-1.41.4-1.3-1.81.3-2.1-1.5-1.7-1.91.9-1.91.9-1.9-1.9-1.9-1.82.2-2.2-2.22.2-2.4-0.2
Bone: cortical apparent density1.11.63.60.80.8-0.81.50.8-1.51.11.51.41.4-1.41.4-1.41.41.41.11.4-0.90.90.9-0.91.01.9
Bone: cortical area0.10.20.9-0.7-0.70.7-0.6-0.40.6-0.1-0.5-0.2-0.30.3-0.30.3-0.3-0.3-0.2-0.30.1-0.00.3-0.20.7-0.9
Bone: cortical porosity0.20.21.80.10.1-0.1-0.40.30.40.4-0.3-0.0-0.10.1-0.10.1-0.1-0.10.0-0.1-0.50.50.6-0.60.3-1.3
Bone: cortical porosity0.20.21.8-0.1-0.10.1-0.60.20.60.4-0.5-0.1-0.20.2-0.20.2-0.2-0.2-0.1-0.2-0.50.50.7-0.70.2-1.4
Bone: cortical thickness0.10.21.2-0.1-0.10.10.20.2-0.10.50.20.50.4-0.40.4-0.40.40.40.50.4-0.50.50.6-0.61.1-0.2
Bone: cortical thickness0.81.02.90.80.8-0.81.30.9-1.10.81.11.21.0-1.01.0-1.01.01.01.01.1-0.60.60.6-0.61.70.7
Bone: cortical tissue density1.31.84.00.90.9-0.91.71.0-1.71.21.61.51.5-1.51.5-1.51.51.51.21.5-1.01.01.0-1.01.02.0
Condit. Reinf. active minus inactive responses0.10.20.4-0.5-0.50.5-0.6-0.30.6-0.1-0.5-0.3-0.40.4-0.40.4-0.3-0.3-0.5-0.3-0.00.0-0.00.1-0.5-0.6
Condit. Reinf. active-inactive response ratio0.30.30.70.80.8-0.80.40.8-0.50.70.50.50.5-0.50.5-0.50.50.50.40.5-0.70.70.4-0.4-0.0-0.0
Condit. Reinf. active responses1.21.52.3-1.5-1.51.5-1.5-1.31.5-1.0-1.4-1.2-1.31.3-1.31.3-1.2-1.2-1.4-1.20.8-0.8-0.70.7-1.0-1.3
Condit. Reinf. inactive responses4.04.96.9-2.6-2.62.6-2.4-2.42.4-2.1-2.4-2.2-2.32.3-2.32.3-2.2-2.2-2.3-2.22.0-1.9-1.61.6-1.7-1.8
Incentive salience index mean0.40.51.3-0.9-0.90.9-1.0-0.51.1-0.1-0.9-0.6-0.70.7-0.60.6-0.6-0.6-0.8-0.60.00.00.10.0-0.6-1.2
Condit. Reinf. lever presses0.91.33.5-1.4-1.41.4-1.5-0.91.6-0.5-1.4-1.0-1.21.2-1.11.1-1.1-1.1-1.3-1.00.5-0.4-0.30.3-0.7-1.9
Condit. Reinf. active minus inactive responses0.60.71.0-0.6-0.60.6-0.9-0.80.9-0.9-0.9-1.0-0.90.9-1.01.0-1.0-1.0-0.7-1.00.9-0.9-0.80.8-0.6-0.9
Condit. Reinf. active-inactive response ratio0.20.20.70.80.8-0.80.40.6-0.50.40.40.40.4-0.40.4-0.40.40.40.50.4-0.40.40.2-0.10.30.0
Condit. Reinf. active responses0.91.21.5-0.9-0.90.9-1.1-1.21.1-1.2-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.0-1.21.2-1.2-0.90.9-0.7-0.7
Condit. Reinf. inactive responses2.22.93.7-1.8-1.81.8-1.5-1.91.5-1.9-1.6-1.8-1.81.8-1.71.7-1.7-1.7-1.7-1.81.9-1.9-1.51.5-1.3-0.8
Condit. Reinf. lever presses0.50.71.3-1.1-1.11.1-1.1-0.91.1-0.6-1.0-0.8-0.90.9-0.80.8-0.8-0.8-0.8-0.80.4-0.4-0.20.2-0.4-1.1
Condit. Reinf. lever reinforcers received0.60.81.1-0.7-0.70.7-1.0-1.00.9-1.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-0.7-1.00.9-0.9-0.60.6-0.5-0.7
Conditioned reinforcement - actives0.10.20.7-0.3-0.40.40.0-0.3-0.1-0.60.0-0.2-0.20.2-0.20.2-0.2-0.2-0.5-0.20.7-0.7-0.80.8-0.4-0.2
Conditioned reinforcement - inactives1.31.97.1-1.3-1.21.2-1.0-0.91.0-1.3-0.9-1.1-1.11.1-1.11.1-1.1-1.1-1.2-1.11.4-1.4-2.52.7-1.9-1.4
Conditioned locomotion0.60.71.41.00.9-0.91.01.2-1.10.71.10.90.9-0.90.9-0.90.90.91.00.9-0.50.5-0.40.40.9-0.4
Patch foraging indifference point 0 sec4.99.012.5-3.3-3.33.3-3.4-3.03.5-2.8-3.4-3.2-3.03.0-3.13.1-3.2-3.2-3.0-3.22.5-2.5-2.22.2-2.3-2.8
Patch foraging indifference point AUC3.34.86.82.52.4-2.42.12.3-2.31.92.32.02.4-2.42.3-2.32.22.22.12.2-1.81.81.9-2.02.61.3
Delay disc. indifference point, 0s delay2.52.74.8-1.6-1.51.5-1.9-1.31.9-1.3-1.8-1.6-1.81.8-1.71.7-1.6-1.6-1.7-1.71.5-1.5-1.61.6-1.4-2.2
Delay disc. indifference point, 16s delay0.30.41.50.10.1-0.10.60.3-0.50.50.50.60.6-0.60.6-0.60.50.50.60.5-0.40.40.9-1.01.20.8
Delay disc. indifference point, 2s delay1.01.15.3-0.9-1.01.0-1.4-0.61.4-0.5-1.3-1.1-1.01.0-1.01.0-1.0-1.0-1.1-1.00.6-0.6-0.80.8-0.4-2.3
Delay disc. indifference point, 24s delay0.50.51.80.50.5-0.50.60.8-0.60.90.70.90.7-0.70.7-0.70.80.80.30.8-0.50.50.7-0.81.3-0.3
Delay disc. indifference point, 4s delay1.01.11.90.60.5-0.50.80.9-0.71.30.81.11.1-1.11.2-1.21.11.11.11.1-1.21.31.3-1.41.30.2
Delay disc. indifference point, 8s delay0.40.52.2-0.1-0.10.10.7-0.0-0.40.60.40.60.6-0.60.7-0.70.70.71.10.6-0.60.60.7-0.71.21.5
Indifference point function ln k1.22.13.0-1.7-1.71.7-1.5-1.71.6-1.1-1.7-1.4-1.61.6-1.61.6-1.5-1.5-1.5-1.41.1-1.1-0.90.8-1.6-0.5
Indifference point function log k1.22.13.0-1.7-1.71.7-1.5-1.71.6-1.1-1.7-1.4-1.61.6-1.61.6-1.5-1.5-1.5-1.41.1-1.1-0.90.8-1.6-0.5
Patch foraging total patch changes 0 sec4.17.611.2-3.1-3.13.1-3.3-2.83.3-2.5-3.2-2.9-2.82.8-2.82.8-3.0-3.0-2.8-2.92.2-2.1-1.81.8-2.0-2.7
Patch foraging total patch changes 12 sec0.70.92.7-1.0-1.11.1-1.3-0.71.2-0.9-1.0-1.1-0.60.6-0.80.8-0.9-0.9-0.8-1.00.7-0.7-0.60.5-0.1-1.6
Patch foraging total patch changes 18 sec0.10.20.6-0.8-0.80.8-0.4-0.40.4-0.5-0.4-0.5-0.10.1-0.30.3-0.5-0.5-0.4-0.40.4-0.4-0.20.20.3-0.4
Patch foraging total patch changes 24 sec0.81.34.6-1.4-1.41.4-1.6-0.91.5-0.8-1.4-1.3-0.80.8-1.01.0-1.2-1.2-0.8-1.10.6-0.6-0.40.4-0.1-2.2
Patch foraging total patch changes 6 sec0.20.30.6-0.7-0.70.7-0.8-0.50.6-0.6-0.6-0.6-0.20.2-0.40.4-0.5-0.5-0.4-0.50.5-0.5-0.40.4-0.1-0.6
Patch foraging time to switch 0 sec0.71.42.6-1.4-1.41.4-0.9-1.20.9-1.4-0.9-1.1-1.11.1-1.11.1-1.0-1.0-1.1-1.11.3-1.3-1.61.6-1.3-0.7
Patch foraging water rate 0 sec0.10.20.80.50.4-0.4-0.10.40.20.6-0.10.2-0.00.0-0.00.00.00.0-0.00.1-0.60.60.9-0.90.4-0.5
Patch foraging water rate 12 sec0.10.20.4-0.3-0.30.3-0.4-0.30.50.3-0.5-0.1-0.40.4-0.40.4-0.3-0.3-0.5-0.2-0.20.30.6-0.6-0.4-0.4
Patch foraging water rate 18 sec2.43.77.31.81.6-1.61.51.8-1.42.41.62.01.7-1.71.8-1.82.02.01.81.9-2.42.42.7-2.71.90.8
Patch foraging water rate 24 sec0.91.23.20.70.7-0.71.40.6-1.11.11.11.30.9-0.91.1-1.11.11.10.91.0-1.01.01.5-1.60.81.8
Patch foraging water rate 6 sec0.40.62.40.50.5-0.50.00.80.11.20.10.60.3-0.30.4-0.40.50.50.30.5-1.21.21.6-1.50.8-0.9
Seeking ratio, delayed vs. immediate footshock2.63.25.3-1.6-1.61.6-1.7-1.21.8-1.6-1.8-1.8-1.91.9-1.91.9-1.9-1.9-1.9-1.71.5-1.5-1.91.9-2.1-2.3
Distance traveled before self-admin0.20.21.50.30.3-0.3-0.20.60.20.60.00.30.4-0.40.3-0.30.30.30.40.3-0.70.70.5-0.50.6-1.2
Distance traveled after self-admin0.80.92.31.21.2-1.20.31.2-0.21.30.50.80.8-0.80.6-0.60.70.70.60.8-1.11.21.5-1.51.3-0.7
Extensor digitorum longus weight5.923.240.94.84.8-4.83.35.4-3.45.83.94.64.6-4.64.6-4.64.64.64.74.6-5.95.96.4-6.35.10.6
Bone: elastic displacement1.61.93.6-1.3-1.31.3-1.7-1.11.7-1.2-1.5-1.5-1.41.4-1.41.4-1.4-1.4-1.5-1.41.0-1.0-0.90.9-1.0-1.9
Bone: elastic work2.32.95.9-1.8-1.81.8-2.2-1.52.3-1.2-2.1-1.8-1.81.8-1.81.8-1.8-1.8-1.7-1.81.1-1.0-0.60.6-0.8-2.4
Bone: endosteal estimation0.30.71.0-1.0-1.01.0-1.0-0.91.0-0.8-0.9-0.8-0.80.8-0.80.8-0.8-0.8-0.6-0.80.7-0.7-0.50.5-0.2-0.9
Bone: endosteal perimeter1.22.53.7-1.5-1.51.5-1.9-1.41.9-1.4-1.8-1.7-1.71.7-1.71.7-1.7-1.7-1.6-1.71.3-1.3-1.11.1-1.0-1.9
Epididymis fat weight0.20.61.3-1.0-1.01.0-0.7-1.20.6-0.8-0.7-0.6-0.80.8-0.80.8-0.6-0.6-0.8-0.70.9-0.9-0.40.3-0.60.6
Delta time in closed arm before/after self-admin1.11.12.5-0.7-0.70.7-0.8-0.80.7-1.2-0.8-1.0-1.11.1-1.01.0-1.0-1.0-0.9-1.01.2-1.2-1.61.6-1.3-0.5
Delta time in open arm before/after self-admin0.10.10.40.30.3-0.30.20.3-0.30.30.30.30.6-0.60.3-0.30.30.30.50.3-0.40.40.3-0.30.3-0.0
Diff in mean of infusions in LGA sessions0.20.20.5-0.5-0.50.5-0.6-0.40.7-0.0-0.5-0.3-0.60.6-0.50.5-0.3-0.3-0.6-0.4-0.10.10.5-0.4-0.6-0.2
Delay discount exponential model param0.50.52.2-0.2-0.10.1-0.5-0.50.3-0.9-0.5-0.7-0.70.7-0.80.8-0.8-0.8-0.9-0.80.8-0.8-0.91.0-1.5-0.0
Extinction: sum of active levers before priming0.60.71.0-1.0-1.01.0-0.7-0.90.8-0.9-0.8-0.8-1.01.0-0.80.8-0.8-0.8-0.9-0.80.9-0.9-0.30.3-0.6-0.2
Active lever presses in extinction session 60.50.51.10.60.6-0.61.00.7-1.00.40.90.80.7-0.70.7-0.70.80.80.60.9-0.30.30.0-0.00.60.9
Bone: final force0.10.10.4-0.6-0.60.6-0.4-0.40.4-0.0-0.4-0.1-0.10.1-0.10.1-0.1-0.10.1-0.2-0.00.00.2-0.20.7-0.4
Bone: final moment0.20.41.2-1.1-1.11.1-0.8-0.80.8-0.3-0.7-0.4-0.40.4-0.40.4-0.4-0.4-0.2-0.40.2-0.20.1-0.10.4-0.6
Food consumed during 24 hour testing period0.10.10.6-0.4-0.40.4-0.20.10.20.5-0.10.10.1-0.10.1-0.10.10.1-0.10.1-0.50.50.7-0.80.3-0.6
Glucose1.62.53.41.21.2-1.21.71.3-1.71.51.71.61.8-1.81.7-1.71.71.71.81.6-1.41.31.4-1.41.81.6
Heart weight0.30.51.2-0.7-0.70.7-0.5-1.10.4-0.8-0.5-0.6-0.70.7-0.70.7-0.5-0.5-0.8-0.70.8-0.8-0.50.4-0.90.8
Delay discount hyperbolic model param0.30.41.6-0.1-0.00.0-0.3-0.50.2-0.8-0.3-0.6-0.60.6-0.60.6-0.6-0.6-0.7-0.60.7-0.7-0.80.8-1.30.3
Intermittent access intake day 1-15 change0.20.30.8-0.2-0.20.2-0.5-0.50.4-0.6-0.4-0.7-0.40.4-0.40.4-0.6-0.6-0.6-0.60.8-0.8-0.80.9-0.6-0.4
Intermittent access intake escalation0.10.20.6-0.2-0.20.2-0.5-0.50.4-0.6-0.3-0.6-0.20.2-0.20.2-0.5-0.5-0.4-0.60.6-0.6-0.70.8-0.5-0.2
Intermittent access intake escalation 20.00.00.10.30.3-0.3-0.2-0.1-0.0-0.10.1-0.20.1-0.10.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.20.2-0.2-0.0
Intermitt. access day 1 inactive lever presses0.20.63.6-0.3-0.30.3-0.3-0.30.1-0.8-0.2-0.5-0.40.4-0.40.4-0.5-0.5-0.5-0.50.9-0.9-1.81.9-1.6-0.7
Intermitt. access day 15 inactive lever presses0.61.32.11.31.3-1.31.31.3-1.21.11.21.11.1-1.11.1-1.11.11.11.21.1-1.11.11.0-1.00.11.4
Intermitt. access escalation Index0.60.81.1-0.7-0.70.7-0.8-0.70.8-0.9-0.9-0.9-1.11.1-1.11.1-1.0-1.0-1.0-0.80.9-0.9-0.90.9-0.8-0.9
Intermittent access day 1 total infusions0.10.20.80.30.1-0.10.50.8-0.50.60.60.60.4-0.40.4-0.40.60.60.10.6-0.40.4-0.00.00.8-0.9
Intermittent access day 15 total infusions0.10.10.70.20.1-0.10.20.2-0.3-0.20.30.10.1-0.10.1-0.10.00.0-0.20.00.3-0.3-0.80.8-0.1-0.3
Intermittent access terminal intake (last 3 days)0.60.71.50.90.8-0.81.00.9-1.10.71.20.91.0-1.01.0-1.01.01.00.80.9-0.60.50.2-0.20.80.5
Intermittent access total infusions0.10.20.50.30.1-0.10.60.4-0.7-0.00.70.40.3-0.30.3-0.30.40.40.10.40.2-0.2-0.70.70.3-0.0
Intermittent access day 1 locomotion0.40.62.1-0.6-0.80.8-0.6-0.40.6-0.5-0.5-0.5-0.70.7-0.70.7-0.6-0.6-0.8-0.50.6-0.6-1.21.2-0.5-1.4
Intermittent access day 15 total locomotion0.51.01.50.90.7-0.71.11.0-1.11.01.21.21.2-1.21.2-1.21.11.11.11.1-0.80.80.3-0.30.70.6
Intermittent access total locomotion0.10.10.40.20.0-0.00.20.3-0.30.20.40.40.2-0.20.2-0.20.30.30.30.3-0.10.1-0.60.60.0-0.2
Intermittent access standard deviation1.22.43.31.61.6-1.61.31.8-1.31.81.41.51.6-1.61.6-1.61.61.61.41.6-1.71.71.7-1.71.60.4
Left kidney weight0.00.10.3-0.4-0.40.4-0.4-0.00.30.3-0.20.20.0-0.00.1-0.10.10.10.40.1-0.50.60.2-0.2-0.1-0.5
Right kidney weight0.31.43.0-1.5-1.51.5-1.7-1.11.5-0.7-1.4-1.1-1.21.2-1.21.2-1.1-1.1-0.9-1.10.5-0.4-0.80.8-1.4-1.6
Cocaine induced anxiety0.81.22.2-1.2-1.41.4-1.4-1.21.5-0.9-1.3-1.1-1.21.2-1.21.2-1.1-1.1-1.0-1.10.6-0.6-0.70.7-0.9-0.8
Post-drug Anxiety4.75.17.6-2.2-2.32.3-2.3-2.82.5-2.4-2.5-2.5-2.52.5-2.52.5-2.5-2.5-2.0-2.52.0-2.0-1.31.2-2.1-0.1
Baseline Anxiety0.40.41.0-0.4-0.30.3-0.4-0.90.4-0.9-0.5-0.8-0.70.7-0.70.7-0.8-0.8-0.6-0.81.0-1.0-0.1-0.1-0.40.5
Tail length0.41.52.7-1.7-1.61.6-1.2-1.51.2-1.1-1.3-1.1-1.21.2-1.21.2-1.1-1.1-1.0-1.11.0-1.0-1.01.1-1.2-0.4
Length with tail0.62.44.1-1.9-1.81.8-2.0-1.71.9-1.1-1.9-1.5-1.81.8-1.71.7-1.5-1.5-1.6-1.51.0-0.9-0.70.7-1.5-1.3
Length without tail0.10.42.6-0.3-0.30.3-1.10.10.80.6-0.6-0.2-0.20.2-0.20.2-0.1-0.1-0.3-0.1-0.70.71.1-1.00.3-1.6
Times rat made contact with spout0.10.10.20.20.2-0.20.40.2-0.40.20.40.30.5-0.50.4-0.40.30.30.30.3-0.20.20.1-0.20.30.1
Lifetime Intake0.20.20.70.50.3-0.30.60.6-0.80.20.80.60.4-0.40.4-0.40.50.50.20.5-0.10.0-0.50.50.4-0.3
Liver weight, left0.20.32.3-0.2-0.20.2-0.60.50.50.9-0.30.20.1-0.10.1-0.10.10.10.20.2-0.91.00.6-0.5-0.1-1.5
Liver weight, right2.03.55.71.41.5-1.51.61.8-1.62.21.72.01.9-1.91.9-1.91.91.91.91.9-2.02.02.4-2.42.11.1
Locomotor activity1.32.05.3-1.5-1.51.5-2.3-1.22.2-0.5-1.9-1.4-1.51.5-1.51.5-1.2-1.2-1.6-1.30.3-0.20.2-0.1-1.0-2.0
Locomotor testing distance6.010.715.2-3.4-3.33.3-3.8-3.33.9-2.8-3.8-3.5-3.63.6-3.63.6-3.4-3.4-3.6-3.42.6-2.5-2.12.2-3.0-2.8
Locomotor testing rearing7.415.020.7-3.9-3.93.9-4.5-3.64.6-3.3-4.5-4.1-4.24.2-4.24.2-4.0-4.0-4.3-4.03.1-3.0-2.62.7-3.7-3.8
Locomotion in novel chamber0.10.10.5-0.3-0.30.3-0.1-0.40.1-0.4-0.1-0.1-0.10.1-0.10.1-0.3-0.30.1-0.10.3-0.3-0.60.70.10.4
Locomotion in novel chamber post-restriction0.61.02.71.61.6-1.60.51.4-0.51.00.80.60.8-0.80.7-0.70.70.70.90.7-1.01.01.3-1.21.4-0.3
Fecal boli incidents, locomotor time 11.21.73.70.50.4-0.41.00.8-1.01.51.11.51.4-1.41.4-1.41.61.61.51.6-1.51.51.5-1.51.90.5
Change in fecal boli incidents, locomotor task0.10.11.20.20.4-0.40.30.0-0.1-0.40.1-0.1-0.10.1-0.10.1-0.2-0.2-0.4-0.40.2-0.3-0.30.3-0.91.1
Time >=10cm from walls, locomotor time 11.21.22.1-1.3-1.31.3-1.2-1.41.1-1.3-1.2-1.2-1.01.0-1.01.0-1.2-1.2-0.8-1.21.0-1.0-0.70.8-1.3-0.0
Bouts of movement, locomotor time 10.91.12.71.61.6-1.60.81.4-0.91.00.80.90.9-0.90.9-0.90.90.91.10.9-1.11.10.2-0.10.7-0.6
Total resting periods, locomotor time 11.82.04.52.02.1-2.11.41.8-1.41.41.41.41.4-1.41.4-1.41.31.31.41.3-1.41.30.5-0.41.1-0.1
Rest time, locomotor task time 11.51.83.81.91.9-1.91.61.8-1.51.11.41.41.3-1.31.3-1.31.21.21.31.2-1.11.00.5-0.51.40.1
Distance moved, locomotor task time 11.11.63.2-1.7-1.81.8-1.3-1.81.2-1.4-1.1-1.4-1.21.2-1.21.2-1.2-1.2-1.1-1.31.3-1.3-0.50.5-1.10.4
Vertical activity count, locomotor time 10.51.23.1-1.4-1.51.5-1.8-1.21.6-0.6-1.3-1.3-1.01.0-1.01.0-1.1-1.1-1.1-1.00.6-0.50.2-0.1-0.5-1.0
Time >=10cm from walls, locomotor time 20.10.10.3-0.00.3-0.30.20.3-0.10.20.20.20.3-0.30.3-0.30.20.20.10.4-0.30.40.3-0.2-0.00.6
Bouts of movement, locomotor time 21.42.23.31.81.7-1.71.51.6-1.51.71.41.51.3-1.31.3-1.31.31.31.21.6-1.51.51.7-1.81.31.1
Total resting periods, locomotor time 22.44.25.32.32.2-2.22.22.1-2.12.32.02.21.9-1.91.9-1.91.91.91.82.2-2.12.02.2-2.31.81.6
Rest time, locomotor task time 28.410.713.73.33.1-3.13.43.2-3.33.23.33.63.4-3.43.4-3.43.33.33.53.4-3.13.12.9-3.03.72.1
Distance moved, locomotor task time 24.35.17.9-2.8-2.72.7-2.4-2.32.3-2.3-2.2-2.5-2.32.3-2.32.3-2.3-2.3-2.2-2.22.2-2.2-1.71.7-2.0-1.0
Vertical activity count, locomotor time 22.12.94.9-2.0-2.02.0-2.2-1.32.1-1.2-2.0-1.9-1.91.9-1.81.8-1.7-1.7-1.9-1.51.3-1.2-0.91.0-1.0-2.1
Light reinforcement 10.20.40.8-0.9-0.90.9-0.1-0.70.2-0.6-0.4-0.5-0.50.5-0.50.5-0.5-0.5-0.7-0.50.8-0.9-0.40.3-0.60.7
Light reinforcement 21.21.85.91.21.2-1.21.91.0-1.81.11.61.51.2-1.21.3-1.31.41.41.11.5-0.70.71.0-1.10.92.4
Bone: marrow area0.30.81.2-1.1-1.11.1-1.1-1.01.0-0.8-1.0-0.9-0.90.9-0.90.9-0.9-0.9-0.7-0.90.8-0.8-0.60.6-0.2-0.9
Bone: maximum diameter0.20.31.60.40.4-0.40.00.7-0.10.70.30.40.4-0.40.4-0.40.40.40.30.4-0.60.61.0-1.01.3-1.0
Bone: maximum force0.10.31.3-0.7-0.70.7-0.7-0.30.60.2-0.5-0.1-0.20.2-0.20.2-0.2-0.20.1-0.2-0.20.20.7-0.61.2-1.0
Bone: maximum moment0.30.61.6-1.2-1.21.2-1.1-0.71.1-0.1-0.9-0.5-0.50.5-0.50.5-0.5-0.5-0.2-0.50.1-0.00.5-0.40.9-1.2
Mean time between licks in bursts1.74.15.6-1.9-1.91.9-1.7-2.31.6-2.4-1.8-2.1-2.02.0-2.02.0-2.1-2.1-1.9-2.12.4-2.4-2.22.1-2.3-0.4
Mean num. licks in bursts0.00.00.2-0.2-0.20.2-0.2-0.00.10.1-0.1-0.00.0-0.00.0-0.0-0.0-0.0-0.1-0.0-0.20.20.3-0.30.1-0.5
Cd content in liver0.10.20.6-0.1-0.20.2-0.60.30.40.6-0.3-0.0-0.10.1-0.20.20.10.10.10.1-0.70.70.7-0.6-0.2-0.8
Co content in liver3.13.64.52.02.0-2.01.52.0-1.72.01.81.91.9-1.91.8-1.81.91.91.71.9-2.02.02.1-2.12.01.0
Cu content in liver1.01.21.71.31.3-1.30.91.3-1.01.21.01.00.9-0.91.0-1.01.01.01.21.0-1.21.21.2-1.20.90.4
Fe content in liver1.62.03.7-1.3-1.31.3-1.1-1.51.1-1.7-1.2-1.5-1.31.3-1.31.3-1.4-1.4-1.4-1.41.5-1.6-1.71.7-1.9-0.1
K content in liver0.20.20.6-0.0-0.00.00.2-0.3-0.2-0.7-0.0-0.3-0.40.4-0.30.3-0.4-0.4-0.4-0.30.7-0.7-0.80.7-0.70.6
Mg content in liver0.60.61.1-0.5-0.50.5-0.3-0.70.4-1.0-0.6-0.8-0.90.9-0.80.8-0.9-0.9-0.9-0.81.0-1.1-1.01.0-0.9-0.2
Mn content in liver1.61.72.5-1.1-1.11.1-1.1-1.31.1-1.5-1.2-1.3-1.41.4-1.31.3-1.4-1.4-1.5-1.41.6-1.6-1.41.4-1.1-0.8
Na content in liver0.30.41.70.10.1-0.1-0.70.30.70.7-0.5-0.0-0.00.0-0.00.0-0.1-0.1-0.1-0.1-0.90.91.3-1.30.4-1.1
Rb content in liver0.10.10.90.10.1-0.10.3-0.0-0.3-0.10.20.10.0-0.00.0-0.00.00.00.10.10.0-0.1-0.20.2-0.60.9
Se content in liver5.46.47.9-2.2-2.22.2-2.8-2.22.7-2.3-2.8-2.7-2.82.8-2.72.7-2.7-2.7-2.8-2.62.1-2.1-2.22.2-2.6-2.8
Sr content in liver0.80.71.5-0.3-0.30.3-0.9-0.50.8-0.8-0.9-0.9-0.90.9-0.90.9-0.9-0.9-1.0-0.90.7-0.7-0.90.9-1.2-1.2
Zn content in liver1.01.21.5-1.0-1.01.0-1.1-0.91.0-1.0-1.1-1.2-1.21.2-1.21.2-1.1-1.1-1.2-1.21.0-1.0-0.91.0-1.1-1.1
Bone: minimum diameter0.30.52.2-1.0-1.01.0-1.1-0.51.0-0.2-0.8-0.5-0.50.5-0.50.5-0.5-0.5-0.4-0.50.1-0.00.2-0.20.4-1.5
Time in familiar zone, hab. session 10.10.00.2-0.0-0.00.0-0.0-0.20.1-0.2-0.2-0.2-0.30.3-0.30.3-0.2-0.2-0.4-0.20.4-0.4-0.20.1-0.0-0.1
Time in novel zone, hab. session 12.42.42.91.41.4-1.41.41.6-1.41.61.61.61.7-1.71.7-1.71.71.71.61.6-1.71.71.6-1.51.41.2
Total zone transitions, hab. session 10.20.31.5-0.4-0.40.4-0.8-0.20.8-0.2-0.7-0.5-0.50.5-0.60.6-0.6-0.6-0.7-0.50.2-0.20.2-0.20.3-1.2
Total locomotion distance, hab. session 11.21.73.7-1.2-1.21.2-1.6-1.01.6-1.0-1.5-1.4-1.41.4-1.41.4-1.3-1.3-1.6-1.41.1-1.0-0.70.7-0.4-1.9
Locomotion velocity, hab. session 12.94.17.1-1.9-1.91.9-2.4-1.72.4-1.7-2.3-2.1-2.22.2-2.22.2-2.1-2.1-2.4-2.11.7-1.7-1.21.2-1.1-2.7
Time in familiar zone, hab. session 20.70.72.40.90.9-0.91.00.5-1.00.40.90.70.9-0.90.9-0.90.80.81.00.7-0.40.40.4-0.40.51.5
Time in novel zone, hab. session 20.40.42.1-0.7-0.70.7-0.8-0.30.8-0.3-0.7-0.6-0.70.7-0.70.7-0.6-0.6-0.8-0.60.3-0.3-0.30.3-0.3-1.4
Total zone transitions, hab. session 20.30.42.6-0.1-0.10.1-0.90.11.00.1-0.8-0.5-0.70.7-0.60.6-0.6-0.6-0.7-0.5-0.10.20.5-0.40.1-1.6
Total locomotion distance, hab. session 20.40.62.6-0.4-0.40.4-0.9-0.21.0-0.3-0.9-0.7-0.90.9-0.90.9-0.8-0.8-1.0-0.70.4-0.4-0.10.1-0.2-1.6
Locomotion velocity, hab. session 20.40.63.6-0.4-0.40.4-1.0-0.11.0-0.2-0.9-0.7-0.90.9-0.90.9-0.8-0.8-1.0-0.70.2-0.20.1-0.0-0.0-1.9
Novel to familiar place preference ratio0.70.81.8-1.3-1.31.3-0.9-1.00.9-0.7-0.9-0.8-0.80.8-0.80.8-0.7-0.7-0.7-0.80.7-0.7-0.60.6-0.3-0.9
Novelty place preference0.91.02.1-1.4-1.41.4-1.1-1.11.0-0.9-1.0-0.9-1.01.0-0.90.9-0.9-0.9-0.9-0.90.9-0.8-0.80.8-0.6-0.9
Time in novel zone, NPP test0.90.91.7-1.3-1.31.3-1.1-1.01.1-0.8-1.1-0.9-1.01.0-0.90.9-0.9-0.9-0.9-0.90.8-0.7-0.70.6-0.6-1.0
Total zone transitions, NPP test1.82.63.6-1.2-1.21.2-1.8-1.31.9-1.4-1.8-1.8-1.91.9-1.81.8-1.8-1.8-1.9-1.81.4-1.4-1.00.9-1.1-1.9
Total locomotion distance, NPP test6.18.310.3-2.6-2.62.6-2.8-2.72.8-3.0-2.9-3.0-3.23.2-3.13.1-3.0-3.0-3.2-3.02.9-2.9-2.72.6-2.5-2.4
Locomotion velocity, NPP test4.76.68.1-2.4-2.42.4-2.4-2.42.5-2.7-2.6-2.7-2.82.8-2.82.8-2.7-2.7-2.8-2.72.7-2.7-2.52.5-2.1-2.2
Intraocular pressure1.62.33.2-1.4-1.31.3-1.3-1.41.4-1.6-1.4-1.7-1.61.6-1.61.6-1.6-1.6-1.6-1.61.6-1.6-1.51.5-1.8-0.4
Delta distance traveled before/after self-admin0.70.81.81.21.2-1.20.81.0-0.71.00.70.80.7-0.70.7-0.70.80.80.40.8-0.80.81.3-1.30.80.4
Delta ambulatory time before/after self-admin0.60.81.61.21.2-1.20.61.0-0.61.10.70.80.6-0.60.7-0.70.80.80.30.8-0.90.91.3-1.30.90.1
Parametrial fat weight1.94.66.8-2.3-2.32.3-1.8-2.61.7-2.5-1.9-2.1-2.12.1-2.12.1-2.1-2.1-2.0-2.12.6-2.6-2.32.2-1.7-0.7
Pavlov. Cond. lever latency0.10.10.50.70.7-0.70.50.3-0.5-0.10.50.10.3-0.30.3-0.30.20.20.50.10.1-0.1-0.30.20.20.5
Pavlov. Cond. magazine entry latency0.00.00.3-0.3-0.30.3-0.0-0.30.10.1-0.1-0.0-0.10.1-0.10.10.00.0-0.2-0.0-0.10.10.3-0.3-0.40.5
Pavlov. Cond. change in total contacts0.30.31.5-0.2-0.20.2-0.40.40.40.8-0.20.30.2-0.20.1-0.10.30.3-0.00.3-0.80.91.2-1.10.8-1.2
Pavlov. Cond. index score0.10.10.5-0.3-0.30.3-0.10.00.20.5-0.10.20.0-0.00.0-0.00.20.2-0.10.2-0.50.50.7-0.70.1-0.1
Pavlov. Cond. latency score0.10.10.3-0.5-0.50.5-0.3-0.20.40.3-0.3-0.0-0.20.2-0.20.2-0.0-0.0-0.3-0.0-0.30.30.5-0.5-0.1-0.2
Pavlov. Cond. lever contacts0.10.10.4-0.6-0.60.6-0.3-0.30.40.1-0.4-0.1-0.30.3-0.20.2-0.1-0.1-0.4-0.1-0.10.10.3-0.3-0.2-0.3
Pavlov. Cond. magazine entry number0.30.41.3-0.3-0.30.3-0.3-0.50.3-0.9-0.3-0.6-0.50.5-0.50.5-0.6-0.6-0.4-0.60.9-0.9-1.21.2-0.4-0.4
Pavlov. Cond. intertrial magazine entries1.51.82.4-1.6-1.61.6-1.6-1.31.5-1.3-1.4-1.4-1.31.3-1.31.3-1.3-1.3-1.3-1.41.1-1.1-0.90.9-1.0-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.9-0.1-0.10.1-0.00.20.10.7-0.00.30.2-0.20.2-0.20.30.30.00.3-0.70.70.9-0.90.2-0.1
Pavlov. Cond. response bias0.30.41.20.20.2-0.20.40.5-0.30.90.40.60.6-0.60.6-0.60.70.70.40.6-0.90.91.1-1.10.50.5
Pavlov. Cond. lever latency0.20.21.00.20.2-0.20.5-0.1-0.4-0.50.2-0.1-0.00.0-0.10.1-0.1-0.1-0.1-0.10.8-0.8-1.01.0-0.40.8
Pavlov. Cond. magazine entry latency0.10.10.6-0.6-0.60.6-0.5-0.20.50.0-0.3-0.2-0.20.2-0.10.1-0.2-0.2-0.3-0.2-0.10.10.4-0.40.1-0.8
Pavlov. Cond. change in total contacts0.71.14.50.50.5-0.50.10.8-0.21.30.50.80.8-0.80.8-0.80.80.80.90.8-1.61.62.1-2.11.1-0.1
Pavlov. Cond. index score0.20.21.1-0.2-0.20.2-0.50.30.40.6-0.20.10.1-0.10.1-0.10.10.10.10.1-0.80.81.1-1.10.3-0.9
Pavlov. Cond. latency score0.20.20.9-0.4-0.40.4-0.7-0.00.60.3-0.4-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.50.60.8-0.8-0.0-1.0
Pavlov. Cond. lever contacts0.20.20.9-0.3-0.30.3-0.50.10.50.5-0.30.10.0-0.00.0-0.00.10.10.10.1-0.70.81.0-0.90.4-0.9
Pavlov. Cond. magazine entry number0.20.31.40.70.7-0.70.80.3-0.70.30.60.50.5-0.50.5-0.50.50.50.60.5-0.20.20.00.00.01.2
Pavlov. Cond. intertrial magazine entries5.17.712.2-2.5-2.52.5-2.1-3.02.1-3.2-2.5-2.8-2.82.8-2.82.8-2.8-2.8-2.8-2.83.3-3.3-3.53.4-2.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.31.3-0.0-0.00.0-0.30.40.30.7-0.00.20.2-0.20.3-0.30.20.20.20.2-0.90.91.2-1.20.5-0.9
Pavlov. Cond. response bias0.20.21.2-0.3-0.30.3-0.60.20.60.5-0.3-0.0-0.00.0-0.00.00.00.00.0-0.0-0.70.70.9-0.90.4-1.1
Time in closed arm before self-admin0.30.40.90.60.6-0.60.50.4-0.50.80.50.50.6-0.60.5-0.50.50.50.40.5-0.70.70.9-1.00.20.6
Time in closed arm after self-admin0.50.51.3-0.6-0.60.6-0.5-0.70.6-0.6-0.6-0.7-0.90.9-0.70.7-0.7-0.7-1.0-0.60.8-0.8-0.90.9-1.2-0.4
Time in open arm before self-admin1.01.11.6-0.9-0.90.9-1.1-0.91.1-1.0-1.2-1.0-1.21.2-1.11.1-1.2-1.2-1.0-0.91.1-1.0-1.21.3-0.7-1.2
Time in open arm after self-admin0.00.00.10.00.0-0.0-0.1-0.00.1-0.2-0.1-0.1-0.00.0-0.20.2-0.1-0.10.2-0.10.1-0.1-0.30.3-0.1-0.2
Bone: periosteal estimation0.20.51.2-1.0-1.01.0-0.9-0.70.9-0.5-0.8-0.6-0.60.6-0.60.6-0.6-0.6-0.4-0.60.5-0.4-0.10.20.4-1.1
Bone: periosteal perimeter0.71.22.7-1.1-1.11.1-1.4-0.91.4-0.9-1.3-1.1-1.21.2-1.21.2-1.2-1.2-1.2-1.20.9-0.8-0.60.6-0.4-1.7
Bone: post-yield work1.72.57.71.01.0-1.01.81.1-1.71.31.71.71.7-1.71.7-1.71.71.71.71.7-1.00.91.4-1.52.81.5
Progressive ratio test 1 active lever presses1.21.52.51.10.9-0.91.61.3-1.51.21.51.51.3-1.31.3-1.31.41.41.11.4-0.90.90.7-0.81.40.6
Progressive ratio test 1 breakpoint1.21.52.51.10.9-0.91.61.4-1.51.31.51.51.3-1.31.3-1.31.41.41.11.4-1.01.00.8-0.81.50.5
Progressive ratio test 1 inactive lever presses0.30.51.1-0.7-0.70.7-0.0-0.50.1-0.7-0.3-0.4-0.70.7-0.70.7-0.5-0.5-1.0-0.51.0-1.0-0.80.8-1.10.6
Progressive ratio test 2 active lever presses0.91.11.80.80.7-0.71.21.3-1.21.21.31.41.2-1.21.2-1.21.21.20.81.3-1.01.00.4-0.40.90.2
Progressive ratio test 2 breakpoint0.91.01.60.80.6-0.61.11.3-1.01.21.21.31.1-1.11.1-1.11.21.20.81.2-1.01.00.4-0.40.80.1
Progressive ratio test 2 inactive lever presses0.20.30.90.30.2-0.21.00.7-0.80.40.90.80.6-0.60.6-0.60.60.60.30.7-0.20.2-0.40.5-0.10.6
Incentive Sensitization - Responses0.10.10.7-0.1-0.10.1-0.10.50.10.60.10.30.3-0.30.3-0.30.30.30.10.4-0.60.6-0.10.2-0.0-0.8
Incentive Sensitization - Breakpoint0.10.10.7-0.1-0.10.1-0.20.50.20.50.00.20.2-0.20.2-0.20.20.20.00.3-0.50.6-0.10.2-0.1-0.8
Sum of active levers in priming session hrs 5-60.20.11.1-0.1-0.10.10.6-0.2-0.6-0.20.40.30.1-0.10.2-0.20.30.30.00.30.3-0.4-0.50.5-0.21.0
Progressive ratio0.50.81.41.00.9-0.90.51.1-0.41.10.50.90.9-0.90.9-0.90.50.50.50.7-1.11.21.2-1.10.7-0.8
Food seeking constrained by brief footshock2.93.57.62.82.8-2.82.32.3-2.31.72.02.01.7-1.71.7-1.71.71.71.61.8-1.51.41.2-1.21.01.1
Seeking ratio, punishment vs. effort0.40.61.61.11.1-1.11.10.7-1.10.40.90.60.6-0.60.5-0.50.80.80.90.7-0.30.30.0-0.10.31.2
Retroperitoneal fat weight0.41.62.6-1.5-1.41.4-0.9-1.50.9-1.4-1.1-1.1-1.31.3-1.31.3-1.1-1.1-1.3-1.11.6-1.6-1.51.4-1.1-0.2
Reaction time number correct0.10.10.70.50.4-0.40.60.2-0.40.20.30.30.2-0.20.1-0.10.30.30.10.2-0.10.10.3-0.3-0.10.8
Reaction time mean minus median0.10.30.5-0.6-0.60.6-0.7-0.50.7-0.4-0.6-0.6-0.60.6-0.50.5-0.5-0.5-0.4-0.50.2-0.20.1-0.1-0.6-0.0
Reaction time mean minus median AUC0.10.10.5-0.5-0.50.5-0.4-0.30.3-0.2-0.4-0.4-0.40.4-0.40.4-0.3-0.3-0.5-0.30.1-0.1-0.0-0.0-0.70.1
Reaction time num false alarms0.50.71.1-0.7-0.80.8-1.0-0.81.0-0.8-1.0-1.0-0.90.9-0.90.9-0.9-0.9-1.0-0.90.6-0.6-0.60.6-0.5-0.7
Reaction time num false alarms AUC0.10.20.4-0.4-0.50.5-0.6-0.40.7-0.3-0.6-0.5-0.40.4-0.40.4-0.4-0.4-0.6-0.40.1-0.1-0.00.10.0-0.4
Reaction time trials correct on left0.10.10.70.50.4-0.40.60.2-0.40.20.30.30.2-0.20.1-0.10.30.30.10.2-0.10.10.3-0.3-0.10.8
Reaction time trials on left0.00.10.80.40.4-0.40.60.1-0.40.10.30.20.1-0.10.1-0.10.20.20.00.2-0.10.00.2-0.2-0.10.9
Reaction time mean0.10.10.30.20.3-0.30.10.2-0.20.30.20.20.2-0.20.3-0.30.30.30.30.2-0.40.40.5-0.6-0.20.5
Reaction time mean AUC0.00.10.30.10.2-0.2-0.10.1-0.00.20.10.10.1-0.10.2-0.20.20.20.20.1-0.40.40.6-0.6-0.20.2
Median of all reaction times0.20.30.50.50.6-0.60.40.5-0.50.50.50.50.5-0.50.6-0.60.60.60.60.5-0.70.70.7-0.70.10.5
Reaction time omissions1.31.92.8-1.6-1.61.6-0.9-1.70.9-1.6-1.2-1.2-1.41.4-1.41.4-1.4-1.4-1.1-1.31.5-1.5-1.61.6-1.60.1
Reaction time false alarm rate0.10.20.4-0.4-0.50.5-0.6-0.40.6-0.3-0.5-0.5-0.40.4-0.30.3-0.4-0.4-0.4-0.40.2-0.2-0.20.30.1-0.5
Reaction time premature initiation rate0.70.92.21.51.5-1.50.61.1-0.71.00.80.80.8-0.80.7-0.70.90.91.00.8-1.11.11.0-1.00.80.2
Reaction time premature initiations0.71.32.91.71.7-1.71.01.3-1.01.11.01.00.9-0.90.8-0.81.11.11.01.0-1.11.11.2-1.20.80.7
Std. dev. reaction times0.00.00.4-0.1-0.10.1-0.0-0.1-0.0-0.00.0-0.0-0.10.10.0-0.00.00.00.20.0-0.20.20.4-0.4-0.20.7
Reaction time trials completed0.00.10.80.40.4-0.40.60.1-0.40.10.30.20.1-0.10.1-0.10.20.20.00.2-0.10.00.2-0.2-0.10.9
Reaction time trials AUC0.00.10.70.40.3-0.30.50.1-0.30.10.30.20.1-0.10.1-0.10.20.2-0.00.1-0.00.00.2-0.2-0.20.8
Run reversals in cocaine runway, females0.20.21.40.0-0.00.0-0.1-0.10.1-0.5-0.1-0.2-0.30.3-0.30.3-0.3-0.3-0.1-0.20.5-0.5-1.11.2-0.0-0.7
Run reversals in cocaine runway, males5.45.49.42.32.3-2.31.72.6-1.62.72.02.22.1-2.12.1-2.12.32.32.42.1-2.72.83.1-3.02.70.9
Latency to leave start box in cocaine runway0.70.92.41.41.5-1.50.81.5-0.71.20.71.00.6-0.60.7-0.70.70.70.40.8-1.01.00.8-0.80.4-0.4
Latency to leave start box in cocaine runway, F1.92.24.71.81.9-1.91.22.2-1.11.91.31.51.3-1.31.4-1.41.41.41.01.4-1.71.81.6-1.51.00.0
Latency to leave start box in cocaine runway, M0.20.20.5-0.1-0.10.1-0.2-0.20.3-0.3-0.5-0.2-0.60.6-0.60.6-0.6-0.6-0.5-0.50.3-0.3-0.60.5-0.7-0.7
Std. dev. time between licks in bursts7.710.512.1-3.3-3.33.3-3.4-3.43.3-3.3-3.4-3.5-3.33.3-3.43.4-3.5-3.5-3.2-3.53.2-3.1-2.82.7-3.0-2.2
Total sessions with >9 infusions0.10.10.30.30.2-0.20.30.5-0.50.20.50.40.3-0.30.3-0.30.30.30.10.3-0.10.1-0.30.30.1-0.6
Short access day 1 total inactive lever presses2.22.94.11.71.7-1.71.41.7-1.61.71.81.71.9-1.91.9-1.91.81.82.01.8-1.81.81.2-1.11.90.1
Short access day 10 total inactive lever presses0.00.00.1-0.0-0.00.0-0.2-0.20.1-0.3-0.2-0.3-0.10.1-0.10.1-0.2-0.2-0.1-0.20.3-0.3-0.30.4-0.2-0.3
Short access day 1 total infusions0.71.01.71.11.0-1.01.11.2-1.20.81.31.21.1-1.11.1-1.11.01.00.71.1-0.80.80.1-0.10.9-0.0
Short access day 10 total infusions0.30.31.70.40.3-0.30.21.0-0.20.80.40.60.4-0.40.4-0.40.50.50.30.5-0.70.70.3-0.31.0-1.3
Short access total infusions0.40.51.00.70.5-0.50.51.0-0.60.80.80.80.7-0.70.7-0.70.70.70.40.8-0.70.70.1-0.10.8-0.9
Short access day 1 locomotion0.20.22.10.20.2-0.2-0.10.8-0.10.80.30.50.3-0.30.3-0.30.40.40.20.4-0.60.60.3-0.20.4-1.4
Short access day 10 total locomotion0.10.20.8-0.2-0.30.3-0.4-0.20.3-0.2-0.3-0.2-0.30.3-0.30.3-0.2-0.2-0.4-0.20.2-0.2-0.70.8-0.6-0.9
Short access total locomotion0.10.11.9-0.1-0.20.2-0.40.20.20.2-0.10.1-0.10.1-0.10.10.00.0-0.10.0-0.20.2-0.20.3-0.0-1.4
One hour access (0.3 mA shock)0.20.22.2-0.3-0.40.4-0.10.3-0.10.00.30.20.1-0.10.1-0.10.20.2-0.00.10.3-0.3-0.70.70.5-1.5
Compulsive drug intake2.12.53.4-1.7-1.61.6-1.4-1.31.3-1.7-1.4-1.5-1.61.6-1.61.6-1.5-1.5-1.3-1.51.8-1.8-1.81.8-1.3-1.7
One hour access (shock baseline)0.30.40.80.80.6-0.60.60.9-0.70.60.90.70.7-0.70.7-0.70.70.70.50.7-0.50.5-0.0-0.00.8-0.5
Social response proportion0.40.42.20.80.9-0.91.10.5-1.10.30.80.60.4-0.40.4-0.40.50.50.40.7-0.20.10.0-0.1-0.31.5
Social responses2.93.76.2-1.6-1.41.4-1.2-2.11.4-2.2-1.7-1.9-2.22.2-2.12.1-2.0-2.0-2.3-2.02.3-2.3-1.91.7-2.50.0
Social time1.21.62.2-1.4-1.41.4-1.5-1.11.4-1.1-1.4-1.3-1.21.2-1.21.2-1.2-1.2-1.5-1.31.0-1.0-1.11.1-1.4-1.3
Soleus weight0.72.02.81.51.5-1.51.31.7-1.31.51.41.41.4-1.41.4-1.41.41.41.41.4-1.41.41.3-1.21.60.3
Bone: stiffness0.20.41.10.50.5-0.50.30.6-0.30.70.40.60.6-0.60.6-0.60.60.60.80.5-0.80.80.9-0.81.10.0
Tibialis anterior weight3.612.223.33.43.4-3.42.14.0-2.24.32.73.33.2-3.23.2-3.23.33.33.43.2-4.44.54.8-4.73.90.1
Time to tail flick, vehicle, before self-admin0.10.10.3-0.6-0.50.5-0.2-0.50.2-0.4-0.3-0.3-0.20.2-0.30.3-0.4-0.4-0.3-0.20.4-0.4-0.0-0.1-0.10.4
Time to tail flick, vehicle, after self-admin2.73.65.62.22.2-2.21.81.9-1.91.81.81.82.1-2.12.0-2.01.71.72.41.8-1.81.81.7-1.61.41.6
Time to tail flick, test, before self-admin1.91.93.1-1.5-1.51.5-1.2-1.81.2-1.7-1.4-1.6-1.31.3-1.51.5-1.5-1.5-1.2-1.61.6-1.6-1.00.9-1.00.2
Time to tail flick, test, after self-admin1.01.15.4-0.7-0.70.70.2-1.6-0.1-1.4-0.4-0.8-0.60.6-0.80.8-0.9-0.9-0.7-0.81.5-1.6-0.90.7-1.32.3
Delta time to tail flick, vehicle, before/after SA2.42.35.11.41.4-1.41.71.1-1.71.21.71.51.7-1.71.6-1.61.51.51.91.5-1.31.31.2-1.21.02.3
Delta time to tail flick, test, before/after SA0.70.74.20.90.9-0.91.40.3-1.40.31.00.90.8-0.80.8-0.80.60.60.60.8-0.10.10.0-0.1-0.22.0
Tibia length2.77.410.5-3.2-3.23.2-3.2-2.93.2-2.4-3.1-2.8-2.82.8-2.82.8-2.8-2.8-2.6-2.82.0-2.0-1.91.9-2.6-2.4
Ambulatory time before self-admin0.10.20.60.30.3-0.3-0.10.50.10.60.10.30.4-0.40.3-0.30.30.30.50.4-0.60.70.7-0.70.8-0.7
Ambulatory time after self-admin1.72.05.11.71.7-1.70.51.6-0.51.90.81.21.1-1.11.1-1.11.21.20.91.3-1.71.72.2-2.21.8-0.5
Bone: tissue strength0.30.30.8-0.9-0.90.9-0.7-0.80.7-0.6-0.6-0.6-0.50.5-0.50.5-0.5-0.5-0.4-0.60.5-0.5-0.20.20.0-0.4
Total heroin consumption1.61.82.90.90.9-0.90.81.6-1.01.71.11.51.6-1.61.5-1.51.51.51.61.5-1.71.71.1-1.01.7-0.5
Bone: trabecular number1.72.83.8-1.6-1.61.6-1.3-1.81.4-1.9-1.5-1.7-1.71.7-1.71.7-1.7-1.7-1.7-1.61.9-2.0-2.01.9-1.8-0.6
Bone: trabecular spacing1.52.03.11.51.5-1.51.01.7-1.01.61.21.31.4-1.41.4-1.41.41.41.31.3-1.61.61.7-1.71.80.2
Bone: trabecular thickness0.60.71.3-1.2-1.21.2-0.9-1.10.9-0.8-0.9-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.8-0.8-0.50.5-0.3-0.4
Bone: trabecular tissue density0.60.81.60.40.4-0.40.60.7-0.61.00.80.91.0-1.01.0-1.01.01.01.11.0-1.21.31.2-1.10.90.5
Water consumed over 24 hours0.50.61.30.80.8-0.80.31.1-0.41.10.40.60.7-0.70.6-0.60.60.60.60.6-1.11.11.1-1.10.9-0.7
Number of responses in last shaping day0.80.92.50.50.4-0.40.50.9-0.61.20.81.00.9-0.90.9-0.90.90.90.80.9-1.21.21.6-1.61.2-0.1