Hub : Genes

Ccdc157

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Ccdc157 0.13 0.06 5.7e-08 0.11 0.11 0.11 0.11 1.9e-09 2.4e-09 2.4e-09 5.3e-09
2 Brain mRNA stability Ccdc157 0.03 0.02 4.3e-03 0.01 0.02 0.01 0.01 1.7e-02 2.6e-03 1.5e-02 1.2e-02
3 PL gene expression Ccdc157 0.07 0.04 1.8e-08 0.1 0.07 0.09 0.09 1.5e-11 2.3e-08 9.5e-10 3.8e-10
4 OFC gene expression Ccdc157 0.39 0.17 5.9e-05 0.13 0.12 0.13 0.11 6.1e-04 1.1e-03 5.0e-04 1.3e-03
5 IC gene expression Ccdc157 0.2 0.09 1.3e-06 0.1 0.14 0.15 0.14 7.1e-05 2.5e-06 6.7e-07 1.6e-06
6 IL gene expression Ccdc157 0.19 0.11 7.3e-03 0.06 0.04 0.04 0.05 1.2e-02 4.7e-02 4.3e-02 2.1e-02
7 Brain gene expression Ccdc157 0.1 0.04 2.6e-11 0.11 0.12 0.11 0.12 9.6e-11 1.8e-11 1.0e-10 2.5e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.50.91.2-1.01.0-1.1-1.0-0.4-0.91.1
Area under the delay curve6.39.710.73.3-3.03.22.93.03.2-3.2
BMI with tail0.41.53.40.9-1.40.81.80.70.9-1.4
BMI without tail0.10.40.90.7-0.80.61.00.50.2-0.7
Body weight2.510.714.72.9-3.82.73.83.23.0-3.3
Weight adjusted by age0.51.51.71.2-1.31.21.11.31.3-1.3
Bone surface0.00.10.20.2-0.10.00.30.30.5-0.2
Bone volume0.00.00.1-0.00.1-0.2-0.00.3-0.00.1
Breakpoint value in progressive ratio session0.10.10.30.3-0.60.20.30.40.1-0.4
Number of licking bursts0.61.92.91.2-1.71.31.71.70.6-1.0
Context. condit. distance diff. score2.83.44.1-1.81.9-1.8-1.8-2.0-1.81.9
Locomotion velocity, session 10.30.41.1-0.20.7-0.3-1.1-0.90.00.0
Locomotion distance, session 11.82.43.2-1.61.8-1.7-1.6-1.4-1.01.5
Locomotion velocity, session 20.50.61.9-0.60.8-0.5-1.4-0.8-0.50.2
Locomotion distance, session 23.04.26.0-1.92.5-2.0-2.1-2.4-1.51.8
Locomotion velocity, session 31.92.13.9-2.01.4-1.9-1.2-1.5-0.61.2
Locomotion distance, session 30.20.31.20.0-0.10.0-0.0-0.31.1-0.7
Stereotopy head waving bouts, day 31.82.23.4-1.91.4-1.8-1.3-1.4-1.11.4
Stereotopy head waving duration, day 33.23.95.3-2.32.0-2.1-1.6-2.1-1.61.9
Locomotion velocity, session 70.10.10.2-0.10.1-0.2-0.4-0.20.4-0.3
Locomotion distance, session 70.81.11.7-1.01.2-1.1-1.1-1.3-0.40.8
Stereotopy head waving bouts, day 70.20.20.40.3-0.40.40.60.20.6-0.5
Stereotopy head waving duration, day 70.10.20.40.3-0.30.40.60.20.5-0.3
Locomotion velocity, session 81.82.13.5-1.01.6-1.0-1.9-1.7-1.51.3
Locomotion distance, session 89.013.114.7-3.53.8-3.6-3.5-3.8-3.43.6
Degree of sensitization distance3.84.16.2-1.72.0-1.8-2.0-1.8-2.52.3
Degree of sensitization stereotypy0.50.61.00.7-0.80.71.00.60.7-0.7
Conditioned locomotion0.60.71.1-1.00.9-1.0-0.4-0.7-0.51.0
Cocaine response after cond. corrected0.81.21.61.0-1.00.81.11.31.2-1.1
Cocaine response after cond. not corrected1.72.53.71.0-1.70.91.81.91.8-1.5
Cocaine response before conditioning0.10.20.3-0.5-0.5-0.50.30.30.4-0.3
Saline control response1.21.62.8-1.21.5-1.1-1.7-1.6-0.70.9
Bone: connectivity density0.50.81.4-1.01.0-1.2-0.8-0.6-0.40.9
Bone: cortical apparent density0.20.40.91.0-0.40.90.70.6-0.0-0.1
Bone: cortical area2.74.46.21.8-2.41.82.52.31.8-1.9
Bone: cortical porosity0.20.20.6-0.4-0.4-0.30.40.30.8-0.5
Bone: cortical porosity0.10.20.4-0.7-0.1-0.60.3-0.10.3-0.1
Bone: cortical thickness2.13.56.21.5-2.11.52.52.11.7-1.5
Bone: cortical thickness0.50.61.1-1.00.8-0.9-0.0-0.6-0.61.0
Bone: cortical tissue density0.30.51.11.1-0.41.00.70.70.1-0.2
Condit. Reinf. active minus inactive responses0.10.20.50.20.20.3-0.3-0.50.7-0.3
Condit. Reinf. active-inactive response ratio0.50.62.1-0.00.9-0.0-1.1-1.4-0.00.1
Condit. Reinf. active responses0.10.10.4-0.20.3-0.1-0.3-0.60.30.0
Condit. Reinf. inactive responses0.20.30.9-0.1-0.70.00.90.80.1-0.1
Incentive salience index mean0.40.51.40.6-0.50.70.30.11.2-0.9
Condit. Reinf. lever presses0.40.61.20.2-0.90.40.90.41.1-0.9
Condit. Reinf. active minus inactive responses0.91.31.8-1.31.0-1.2-1.4-1.1-1.11.0
Condit. Reinf. active-inactive response ratio0.00.10.2-0.10.3-0.2-0.4-0.30.10.0
Condit. Reinf. active responses2.33.25.3-1.71.9-1.6-2.3-1.9-1.51.6
Condit. Reinf. inactive responses2.23.24.3-1.71.9-1.5-2.1-1.9-1.61.7
Condit. Reinf. lever presses0.60.91.2-1.11.0-0.9-1.1-1.0-0.70.9
Condit. Reinf. lever reinforcers received1.92.74.4-1.51.8-1.5-2.1-1.7-1.21.4
Conditioned reinforcement - actives0.62.53.01.4-1.71.51.71.51.7-1.6
Conditioned reinforcement - inactives1.85.06.32.5-2.02.51.82.02.5-2.3
Conditioned locomotion2.02.94.11.7-1.81.51.82.01.6-1.5
Patch foraging indifference point 0 sec0.10.40.90.9-0.50.70.40.8-0.2-0.3
Patch foraging indifference point AUC0.41.03.0-0.51.1-0.7-1.7-1.3-0.50.3
Delay disc. indifference point, 0s delay5.36.08.12.4-2.32.32.92.12.8-2.2
Delay disc. indifference point, 16s delay4.86.88.62.9-2.52.92.22.62.4-2.6
Delay disc. indifference point, 2s delay5.46.18.52.4-2.32.42.42.42.9-2.4
Delay disc. indifference point, 24s delay3.25.17.92.2-2.12.22.32.02.8-2.2
Delay disc. indifference point, 4s delay4.34.56.52.1-2.02.01.82.22.6-2.3
Delay disc. indifference point, 8s delay1.32.13.01.7-1.31.71.21.31.2-1.6
Indifference point function ln k0.10.20.4-0.4-0.2-0.40.40.7-0.10.3
Indifference point function log k0.10.20.4-0.4-0.2-0.40.40.7-0.10.3
Patch foraging total patch changes 0 sec0.10.30.80.9-0.60.70.30.7-0.1-0.5
Patch foraging total patch changes 12 sec0.10.10.30.2-0.5-0.10.50.3-0.1-0.2
Patch foraging total patch changes 18 sec0.20.41.01.0-0.50.7-0.00.10.6-0.9
Patch foraging total patch changes 24 sec1.03.34.7-1.42.1-1.6-1.7-2.2-1.91.8
Patch foraging total patch changes 6 sec0.10.20.50.7-0.30.4-0.30.40.1-0.5
Patch foraging time to switch 0 sec0.10.31.80.3-0.30.31.30.1-0.30.5
Patch foraging water rate 0 sec0.10.51.50.3-1.00.3-0.00.70.7-1.2
Patch foraging water rate 12 sec0.20.61.5-1.20.3-1.2-1.0-0.70.10.0
Patch foraging water rate 18 sec0.51.22.1-1.40.7-1.4-0.6-0.2-1.31.3
Patch foraging water rate 24 sec0.20.30.8-0.8-0.1-0.9-0.6-0.6-0.20.1
Patch foraging water rate 6 sec0.20.20.7-0.8-0.2-0.8-0.5-0.0-0.0-0.0
Seeking ratio, delayed vs. immediate footshock0.20.20.80.00.5-0.0-0.90.1-0.80.0
Distance traveled before self-admin0.10.30.80.30.70.3-0.90.0-0.40.2
Distance traveled after self-admin0.10.10.20.40.40.5-0.20.30.1-0.0
Extensor digitorum longus weight2.610.613.92.9-3.72.53.23.73.2-3.3
Bone: elastic displacement0.10.10.60.00.20.1-0.10.1-0.80.6
Bone: elastic work0.30.30.90.2-0.80.30.81.0-0.20.1
Bone: endosteal estimation0.00.00.2-0.0-0.2-0.0-0.10.2-0.4-0.0
Bone: endosteal perimeter0.41.11.41.2-1.11.10.61.20.8-1.1
Epididymis fat weight0.73.36.11.4-2.31.32.52.01.4-1.6
Delta time in closed arm before/after self-admin5.04.75.9-2.42.0-2.4-1.7-2.2-2.02.3
Delta time in open arm before/after self-admin5.86.910.63.3-2.42.92.22.42.3-2.7
Diff in mean of infusions in LGA sessions0.10.10.40.30.70.3-0.4-0.3-0.30.2
Delay discount exponential model param6.79.110.3-3.12.9-3.1-2.8-2.9-3.23.1
Extinction: sum of active levers before priming0.71.11.71.2-0.81.30.90.81.0-1.2
Active lever presses in extinction session 60.50.51.00.5-0.80.50.90.71.0-0.7
Bone: final force0.30.51.30.7-0.70.81.20.70.1-0.3
Bone: final moment0.40.71.50.8-0.90.91.21.00.1-0.4
Food consumed during 24 hour testing period0.10.20.40.5-0.30.6-0.40.1-0.1-0.6
Glucose13.020.529.35.3-4.05.22.33.25.2-5.4
Heart weight0.50.81.40.5-1.20.81.10.60.9-1.0
Delay discount hyperbolic model param7.19.210.7-3.12.9-3.1-2.8-2.9-3.33.1
Intermittent access intake day 1-15 change0.21.21.91.1-1.11.40.90.71.1-1.3
Intermittent access intake escalation0.31.52.11.1-1.31.41.00.91.4-1.4
Intermittent access intake escalation 20.30.60.80.6-0.90.90.80.70.5-0.8
Intermitt. access day 1 inactive lever presses0.00.20.7-0.0-0.4-0.0-0.00.20.8-0.5
Intermitt. access day 15 inactive lever presses0.31.42.81.2-1.11.30.30.51.6-1.7
Intermitt. access escalation Index0.20.61.4-0.60.8-0.6-0.6-1.2-0.50.7
Intermittent access day 1 total infusions0.92.83.51.9-1.41.81.71.61.8-1.4
Intermittent access day 15 total infusions2.35.56.92.4-2.22.62.12.12.6-2.4
Intermittent access terminal intake (last 3 days)2.03.64.62.0-1.82.11.71.81.9-1.9
Intermittent access total infusions3.64.25.22.2-1.92.31.72.02.2-2.0
Intermittent access day 1 locomotion0.00.10.30.20.50.0-0.4-0.0-0.00.2
Intermittent access day 15 total locomotion1.45.46.52.3-2.42.32.62.22.2-2.2
Intermittent access total locomotion2.32.73.61.9-1.51.71.11.61.8-1.7
Intermittent access standard deviation0.00.10.40.1-0.10.30.00.20.6-0.3
Left kidney weight0.10.71.7-0.8-1.1-0.71.30.80.10.1
Right kidney weight0.11.02.8-0.9-1.0-0.81.71.2-0.10.3
Cocaine induced anxiety0.71.93.21.1-1.41.31.01.31.5-1.8
Post-drug Anxiety2.02.33.11.2-1.61.41.61.31.7-1.8
Baseline Anxiety0.20.31.00.5-0.30.51.00.00.6-0.0
Tail length0.73.76.21.7-2.21.61.62.51.8-1.9
Length with tail1.56.710.72.1-3.22.12.63.32.4-2.3
Length without tail0.73.65.71.3-2.41.42.32.21.8-1.6
Times rat made contact with spout0.30.31.30.10.50.1-1.1-0.8-0.4-0.2
Lifetime Intake3.13.95.12.2-1.82.21.52.02.0-1.9
Liver weight, left0.50.92.0-1.40.6-1.2-0.6-0.6-0.81.0
Liver weight, right0.71.22.2-1.50.8-1.3-0.3-0.9-1.01.3
Locomotor activity0.30.41.20.3-0.60.4-0.30.01.0-1.1
Locomotor testing distance0.30.71.30.3-1.10.30.80.81.1-1.0
Locomotor testing rearing0.72.63.51.4-1.71.41.41.61.9-1.9
Locomotion in novel chamber0.60.81.6-1.20.8-1.3-0.6-0.8-0.60.9
Locomotion in novel chamber post-restriction0.82.33.6-1.21.9-1.2-1.6-1.9-1.41.3
Fecal boli incidents, locomotor time 10.20.41.1-0.40.6-0.5-1.1-0.5-0.70.4
Change in fecal boli incidents, locomotor task0.30.30.8-0.30.7-0.4-0.8-0.9-0.40.3
Time >=10cm from walls, locomotor time 10.20.21.30.4-0.00.31.20.2-0.20.4
Bouts of movement, locomotor time 10.20.20.50.6-0.20.50.50.10.7-0.3
Total resting periods, locomotor time 10.30.30.90.6-0.20.60.4-0.01.0-0.5
Rest time, locomotor task time 10.00.10.2-0.20.4-0.1-0.4-0.40.2-0.0
Distance moved, locomotor task time 10.10.20.40.5-0.30.40.30.5-0.60.0
Vertical activity count, locomotor time 10.00.20.80.40.30.5-0.6-0.0-0.90.3
Time >=10cm from walls, locomotor time 20.10.20.5-0.20.4-0.20.1-0.2-0.70.5
Bouts of movement, locomotor time 20.00.10.3-0.50.0-0.60.1-0.20.20.0
Total resting periods, locomotor time 20.00.10.2-0.50.1-0.5-0.1-0.40.3-0.1
Rest time, locomotor task time 20.30.60.9-0.60.9-0.6-0.9-0.9-0.60.6
Distance moved, locomotor task time 20.10.10.30.1-0.20.20.40.2-0.50.2
Vertical activity count, locomotor time 20.00.10.40.4-0.10.60.10.3-0.1-0.1
Light reinforcement 10.10.41.1-0.2-0.8-0.11.00.60.8-0.5
Light reinforcement 20.00.10.2-0.3-0.3-0.20.20.3-0.40.2
Bone: marrow area0.00.00.2-0.1-0.1-0.1-0.20.1-0.40.0
Bone: maximum diameter3.57.08.92.7-3.02.62.62.72.3-2.7
Bone: maximum force0.20.30.60.6-0.60.60.80.7-0.2-0.1
Bone: maximum moment0.30.51.00.7-0.80.70.81.0-0.2-0.2
Mean time between licks in bursts0.00.20.90.00.40.1-1.0-0.5-0.40.0
Mean num. licks in bursts0.92.55.3-1.01.9-1.2-2.3-2.1-0.90.9
Cd content in liver0.40.40.70.8-0.60.60.40.40.6-0.8
Co content in liver0.40.41.00.5-0.70.30.40.61.0-0.8
Cu content in liver0.10.10.20.5-0.20.40.30.40.4-0.2
Fe content in liver1.41.83.1-1.11.8-1.0-1.7-1.6-0.71.1
K content in liver3.23.24.61.4-1.81.31.92.22.1-1.5
Mg content in liver3.23.55.01.3-2.21.22.22.02.1-1.8
Mn content in liver0.10.10.2-0.2-0.1-0.1-0.00.30.5-0.2
Na content in liver4.45.06.42.5-1.72.51.72.12.5-2.4
Rb content in liver0.80.91.41.2-0.91.20.61.00.7-0.8
Se content in liver2.63.04.51.3-2.01.41.72.11.8-1.7
Sr content in liver3.53.04.42.1-1.82.11.31.71.2-1.8
Zn content in liver0.10.20.4-0.1-0.6-0.30.40.60.2-0.3
Bone: minimum diameter0.10.10.2-0.4-0.0-0.5-0.2-0.1-0.50.3
Time in familiar zone, hab. session 10.91.01.9-0.21.3-0.2-1.0-1.0-1.41.1
Time in novel zone, hab. session 10.70.81.50.3-1.20.30.91.20.9-0.9
Total zone transitions, hab. session 10.60.81.7-0.31.3-0.2-1.3-1.0-0.70.7
Total locomotion distance, hab. session 10.10.20.7-0.10.6-0.1-0.8-0.30.10.0
Locomotion velocity, hab. session 10.20.30.6-0.40.7-0.4-0.8-0.70.20.1
Time in familiar zone, hab. session 22.52.84.5-1.21.9-1.2-1.2-1.6-2.12.1
Time in novel zone, hab. session 22.02.23.71.2-1.91.11.11.51.5-1.9
Total zone transitions, hab. session 20.10.10.20.20.20.2-0.4-0.20.4-0.3
Total locomotion distance, hab. session 20.20.30.70.6-0.40.60.10.20.7-0.8
Locomotion velocity, hab. session 20.40.61.10.8-0.70.80.30.41.0-1.1
Novel to familiar place preference ratio1.01.32.71.2-0.81.20.50.61.6-1.6
Novelty place preference1.01.32.51.1-0.91.10.50.61.6-1.6
Time in novel zone, NPP test0.91.02.11.1-0.81.00.40.61.4-1.4
Total zone transitions, NPP test0.20.30.5-0.70.6-0.7-0.4-0.4-0.00.6
Total locomotion distance, NPP test0.00.10.2-0.30.2-0.3-0.2-0.10.40.1
Locomotion velocity, NPP test0.10.10.6-0.0-0.0-0.00.10.20.8-0.2
Intraocular pressure0.10.20.50.40.30.4-0.5-0.70.4-0.3
Delta distance traveled before/after self-admin0.20.30.90.1-0.40.10.90.20.8-0.2
Delta ambulatory time before/after self-admin0.10.10.2-0.30.1-0.30.4-0.00.50.2
Parametrial fat weight1.33.05.32.2-0.92.20.2-0.12.3-2.3
Pavlov. Cond. lever latency0.20.30.60.8-0.40.70.20.70.3-0.5
Pavlov. Cond. magazine entry latency2.02.53.5-1.61.6-1.5-1.8-1.9-1.31.3
Pavlov. Cond. change in total contacts0.30.41.00.5-0.40.50.30.01.0-0.9
Pavlov. Cond. index score1.62.02.9-1.61.5-1.5-1.3-1.7-1.01.3
Pavlov. Cond. latency score1.41.82.5-1.51.4-1.4-1.1-1.6-1.01.3
Pavlov. Cond. lever contacts0.80.91.5-1.20.8-1.2-0.6-1.2-0.60.8
Pavlov. Cond. magazine entry number2.22.84.71.8-1.81.61.92.21.0-1.2
Pavlov. Cond. intertrial magazine entries0.40.51.30.2-0.80.31.01.10.7-0.2
Pavlov. Cond. lever-magazine prob. diff.1.82.23.1-1.71.5-1.6-1.3-1.7-1.11.4
Pavlov. Cond. response bias0.70.91.5-1.20.8-1.1-0.9-1.2-0.30.6
Pavlov. Cond. lever latency2.53.55.31.7-2.01.62.32.31.7-1.4
Pavlov. Cond. magazine entry latency0.00.00.10.30.00.3-0.10.1-0.2-0.1
Pavlov. Cond. change in total contacts0.41.11.8-0.51.3-0.5-1.4-1.1-1.20.9
Pavlov. Cond. index score0.81.32.0-0.91.3-0.8-1.4-1.3-1.21.0
Pavlov. Cond. latency score1.01.62.4-1.01.4-1.0-1.5-1.4-1.31.1
Pavlov. Cond. lever contacts2.63.95.6-1.92.1-1.7-2.3-2.4-1.71.6
Pavlov. Cond. magazine entry number0.10.10.3-0.6-0.0-0.50.1-0.10.6-0.0
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.80.1-0.7-0.1-0.10.30.1
Pavlov. Cond. lever-magazine prob. diff.0.91.52.1-0.91.3-0.9-1.5-1.3-1.31.1
Pavlov. Cond. response bias1.11.62.3-1.01.3-0.9-1.5-1.5-1.31.0
Time in closed arm before self-admin0.20.40.9-0.90.2-0.80.0-0.0-1.00.8
Time in closed arm after self-admin3.03.45.5-2.41.4-2.1-0.9-1.5-2.12.1
Time in open arm before self-admin0.00.00.1-0.30.1-0.2-0.0-0.30.00.1
Time in open arm after self-admin1.82.03.92.0-1.11.71.00.91.3-1.6
Bone: periosteal estimation0.51.21.80.9-1.40.91.21.30.6-0.9
Bone: periosteal perimeter1.73.34.21.7-2.11.61.91.91.7-1.8
Bone: post-yield work0.10.10.40.6-0.00.5-0.30.3-0.4-0.0
Progressive ratio test 1 active lever presses1.52.63.51.9-1.31.91.11.61.7-1.7
Progressive ratio test 1 breakpoint1.52.63.41.8-1.31.81.21.61.8-1.7
Progressive ratio test 1 inactive lever presses2.05.27.92.8-1.92.81.52.02.2-2.4
Progressive ratio test 2 active lever presses2.43.45.12.1-1.72.21.61.61.8-1.8
Progressive ratio test 2 breakpoint2.43.04.51.9-1.62.11.61.41.7-1.7
Progressive ratio test 2 inactive lever presses1.96.07.22.5-2.42.72.51.92.5-2.6
Incentive Sensitization - Responses0.71.93.21.6-1.31.81.50.91.2-1.2
Incentive Sensitization - Breakpoint0.71.72.91.5-1.31.71.50.81.1-1.1
Sum of active levers in priming session hrs 5-60.70.71.50.7-0.80.81.20.80.7-0.6
Progressive ratio0.10.40.91.0-0.40.90.40.60.4-0.3
Food seeking constrained by brief footshock2.83.54.12.0-1.81.91.71.92.0-1.7
Seeking ratio, punishment vs. effort0.10.20.6-0.3-0.4-0.30.30.30.7-0.5
Retroperitoneal fat weight0.31.32.31.5-0.61.20.5-0.21.5-1.4
Reaction time number correct0.10.40.9-0.70.4-0.7-1.0-0.5-0.70.3
Reaction time mean minus median0.00.10.30.4-0.50.40.30.10.2-0.5
Reaction time mean minus median AUC0.10.50.90.5-0.90.50.90.40.7-0.7
Reaction time num false alarms0.40.81.30.9-0.80.91.10.80.9-0.7
Reaction time num false alarms AUC0.30.61.40.7-0.70.71.20.80.7-0.4
Reaction time trials correct on left0.10.40.9-0.70.4-0.7-1.0-0.5-0.70.3
Reaction time trials on left0.10.41.0-0.70.4-0.7-1.0-0.5-0.70.4
Reaction time mean0.00.10.30.1-0.30.10.60.10.1-0.0
Reaction time mean AUC0.00.00.2-0.1-0.2-0.10.4-0.00.00.1
Median of all reaction times0.00.10.3-0.1-0.1-0.10.5-0.00.00.2
Reaction time omissions0.30.40.6-0.80.7-0.7-0.7-0.80.10.4
Reaction time false alarm rate0.91.22.81.0-0.91.11.71.11.0-0.6
Reaction time premature initiation rate4.46.88.5-2.92.6-2.8-2.1-2.7-2.52.6
Reaction time premature initiations1.95.97.3-2.72.3-2.7-2.2-2.4-2.42.2
Std. dev. reaction times0.10.30.40.6-0.60.60.60.10.4-0.5
Reaction time trials completed0.10.41.0-0.70.4-0.7-1.0-0.5-0.70.4
Reaction time trials AUC0.10.30.8-0.70.3-0.7-0.9-0.3-0.60.3
Run reversals in cocaine runway, females0.20.20.5-0.00.6-0.00.2-0.7-0.00.5
Run reversals in cocaine runway, males0.00.00.10.3-0.10.3-0.10.1-0.2-0.2
Latency to leave start box in cocaine runway0.10.10.40.30.30.4-0.40.10.6-0.1
Latency to leave start box in cocaine runway, F0.20.30.40.6-0.30.60.50.60.6-0.4
Latency to leave start box in cocaine runway, M0.30.31.1-0.10.6-0.0-1.0-0.50.6-0.1
Std. dev. time between licks in bursts0.51.01.5-0.81.2-0.7-1.2-1.0-1.11.0
Total sessions with >9 infusions0.20.31.0-0.30.6-0.2-1.0-0.40.00.3
Short access day 1 total inactive lever presses1.63.25.12.2-1.62.30.71.61.8-1.9
Short access day 10 total inactive lever presses0.00.20.6-0.7-0.1-0.6-0.8-0.20.4-0.2
Short access day 1 total infusions0.00.10.10.10.2-0.0-0.30.20.40.2
Short access day 10 total infusions0.10.10.40.30.40.2-0.6-0.20.00.1
Short access total infusions0.30.51.11.0-0.20.9-0.00.80.7-0.5
Short access day 1 locomotion0.61.02.5-0.71.0-0.9-1.6-0.6-1.01.0
Short access day 10 total locomotion0.93.88.8-1.32.4-1.6-3.0-1.6-1.61.7
Short access total locomotion2.94.49.4-1.72.3-1.9-3.1-1.8-1.81.8
One hour access (0.3 mA shock)2.22.64.62.0-1.32.21.11.51.3-1.6
Compulsive drug intake2.43.54.3-2.02.0-1.9-1.7-1.8-1.72.1
One hour access (shock baseline)2.66.98.82.8-2.53.02.12.52.6-2.7
Social response proportion0.20.20.70.7-0.30.90.10.30.2-0.5
Social responses0.30.30.60.7-0.60.70.20.30.5-0.8
Social time0.10.20.4-0.30.5-0.4-0.3-0.5-0.60.6
Soleus weight0.61.94.10.8-2.00.71.52.00.8-1.2
Bone: stiffness0.10.20.4-0.60.3-0.60.1-0.5-0.10.4
Tibialis anterior weight1.55.36.92.2-2.62.02.12.42.3-2.4
Time to tail flick, vehicle, before self-admin0.10.10.80.0-0.20.30.9-0.2-0.20.1
Time to tail flick, vehicle, after self-admin0.30.51.3-0.50.9-0.3-1.0-1.10.20.3
Time to tail flick, test, before self-admin0.81.02.4-1.60.6-1.3-1.1-0.9-0.30.5
Time to tail flick, test, after self-admin1.11.11.80.7-1.30.90.61.21.2-1.3
Delta time to tail flick, vehicle, before/after SA0.60.62.3-0.21.0-0.4-1.5-0.80.20.2
Delta time to tail flick, test, before/after SA1.21.52.41.6-1.21.51.01.20.8-1.1
Tibia length0.20.40.9-1.00.1-0.70.4-0.0-0.80.9
Ambulatory time before self-admin0.10.20.50.70.50.6-0.50.4-0.3-0.0
Ambulatory time after self-admin0.10.20.40.30.60.3-0.60.1-0.20.2
Bone: tissue strength0.20.21.00.1-0.0-0.1-0.10.1-1.00.5
Total heroin consumption0.20.31.0-0.40.3-0.6-0.3-0.0-1.00.6
Bone: trabecular number0.20.30.6-0.70.4-0.8-0.30.0-0.40.7
Bone: trabecular spacing1.01.53.31.8-0.91.80.60.80.6-1.2
Bone: trabecular thickness1.42.04.1-2.01.0-2.0-0.6-0.7-1.21.6
Bone: trabecular tissue density0.00.10.20.30.10.40.1-0.2-0.30.1
Water consumed over 24 hours0.30.51.70.10.50.2-1.2-0.4-1.30.3
Number of responses in last shaping day0.20.21.0-0.30.5-0.2-0.4-1.00.20.1