Hub : Genes

Ccdc150

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	OFC	alternative TSS	XM_039083605.2	0.26	0.23	7.4e-03	0.04	0.05	0.05	0.07	3.4e-02	2.8e-02	3.0e-02	9.2e-03
2	Liver	gene expression	Ccdc150	0.03	0.03	9.2e-04	0.03	0.02	0.03	0.03	1.9e-04	9.2e-04	2.4e-04	3.9e-04
3	NAcc	gene expression	Ccdc150	0.03	0.02	3.3e-03	0.01	0.01	0	0	4.0e-02	4.1e-02	1.2e-01	5.3e-02
4	PL	gene expression	Ccdc150	0.05	0.04	9.3e-04	0.03	0.01	0.01	0.02	5.1e-04	3.2e-02	1.7e-02	6.0e-03
5	Adipose	gene expression	Ccdc150	0.09	0.06	1.0e-08	0.07	0.07	0.07	0.07	6.7e-08	2.2e-08	4.0e-08	2.7e-08
6	Brain	gene expression	Ccdc150	0.08	0.06	5.5e-05	0.04	0.04	0.04	0.04	2.1e-04	5.1e-05	2.4e-04	7.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Bone: apparent density	5.0	8.6	13.3	2.6	-3.7	-3.0	-3.2	-3.0	-2.0
Area under the delay curve	0.2	0.3	0.7	-0.9	0.4	0.3	0.7	0.1	-0.4
BMI with tail	3.2	11.0	20.1	-3.3	4.5	3.4	3.6	3.0	1.6
BMI without tail	0.6	1.9	2.9	-0.5	1.3	1.4	1.7	1.6	1.5
Body weight	1.0	4.5	12.3	3.5	-1.8	-2.5	-1.8	-1.4	0.2
Weight adjusted by age	1.3	2.0	3.0	0.9	-1.7	-1.4	-1.6	-1.5	-1.3
Bone surface	4.7	8.6	13.2	2.6	-3.6	-3.1	-3.4	-2.8	-1.8
Bone volume	5.2	9.3	13.6	2.6	-3.7	-3.1	-3.3	-3.1	-2.2
Breakpoint value in progressive ratio session	0.6	0.7	1.0	0.6	-0.5	-0.9	-1.0	-1.0	-0.8
Number of licking bursts	0.1	0.2	0.4	-0.3	0.7	0.5	0.5	-0.1	-0.5
Context. condit. distance diff. score	2.2	2.7	4.1	-1.2	1.7	1.6	2.0	1.7	1.5
Locomotion velocity, session 1	1.9	2.0	4.5	-2.1	0.5	1.7	1.7	1.2	0.3
Locomotion distance, session 1	0.5	0.6	1.0	-0.9	0.2	0.9	1.0	0.9	0.6
Locomotion velocity, session 2	1.6	1.8	4.5	-2.1	0.4	1.5	1.6	1.1	0.2
Locomotion distance, session 2	0.1	0.2	0.3	-0.5	0.4	0.4	0.5	0.5	0.4
Locomotion velocity, session 3	0.4	0.4	1.5	0.4	0.1	0.3	-0.1	0.8	1.2
Locomotion distance, session 3	0.1	0.1	0.3	0.1	0.2	0.3	0.2	0.4	0.5
Stereotopy head waving bouts, day 3	2.0	2.3	3.2	-0.9	1.4	1.7	1.5	1.8	1.7
Stereotopy head waving duration, day 3	0.8	0.9	1.8	-0.4	0.5	0.9	1.0	1.2	1.4
Locomotion velocity, session 7	1.4	1.5	4.7	-2.2	0.2	1.6	0.8	1.1	0.1
Locomotion distance, session 7	0.1	0.1	0.5	-0.7	0.2	0.3	-0.3	0.2	-0.1
Stereotopy head waving bouts, day 7	0.2	0.2	0.4	-0.6	-0.7	0.3	0.0	-0.1	-0.4
Stereotopy head waving duration, day 7	0.2	0.2	0.3	-0.6	-0.6	0.5	0.3	0.4	0.3
Locomotion velocity, session 8	1.1	1.3	4.7	-2.2	0.3	1.0	1.1	0.3	-0.8
Locomotion distance, session 8	1.6	2.4	3.0	-1.4	1.4	1.6	1.7	1.7	1.3
Degree of sensitization distance	0.4	0.5	1.1	-0.2	-0.3	-0.5	-0.8	-0.8	-1.0
Degree of sensitization stereotypy	0.4	0.4	1.0	-0.4	-1.0	-0.2	-0.5	-0.6	-0.9
Conditioned locomotion	2.5	2.9	4.7	2.2	-1.1	-2.0	-2.0	-1.7	-0.9
Cocaine response after cond. corrected	2.9	3.5	6.8	0.8	-1.7	-1.6	-1.5	-2.4	-2.6
Cocaine response after cond. not corrected	3.7	4.4	7.0	0.9	-2.2	-1.8	-1.9	-2.5	-2.6
Cocaine response before conditioning	0.2	0.2	0.5	-0.1	0.1	0.4	0.4	0.7	0.7
Saline control response	0.2	0.3	0.7	0.2	0.6	0.3	0.7	0.6	0.8
Bone: connectivity density	2.4	3.8	6.6	1.4	-2.6	-1.8	-2.1	-2.0	-1.5
Bone: cortical apparent density	4.0	5.5	8.7	-2.7	2.9	2.4	2.5	2.0	0.9
Bone: cortical area	0.2	0.3	0.7	0.4	-0.6	-0.7	-0.8	-0.4	-0.2
Bone: cortical porosity	2.6	2.8	5.2	2.0	-2.3	-1.8	-1.6	-1.1	-0.2
Bone: cortical porosity	4.9	5.3	8.3	2.9	-2.8	-2.6	-2.4	-1.7	-0.4
Bone: cortical thickness	0.7	1.1	2.2	-1.1	1.5	1.0	1.0	1.0	0.6
Bone: cortical thickness	1.0	1.2	3.8	-1.9	1.2	0.9	0.6	0.2	-0.9
Bone: cortical tissue density	4.1	5.6	8.9	-2.7	3.0	2.5	2.5	2.0	0.9
Condit. Reinf. active minus inactive responses	0.9	1.0	1.9	0.4	-0.5	-1.1	-0.8	-1.3	-1.4
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.5	-0.2	-0.3	-0.2	-0.1	-0.6	-0.7
Condit. Reinf. active responses	2.0	2.5	3.9	1.0	-1.1	-1.8	-1.5	-2.0	-1.9
Condit. Reinf. inactive responses	0.9	1.1	1.6	0.8	-0.6	-1.2	-1.1	-1.3	-1.2
Incentive salience index mean	1.5	1.9	3.8	0.5	-0.8	-1.4	-1.2	-1.8	-2.0
Condit. Reinf. lever presses	0.9	1.2	1.7	0.7	-0.8	-1.1	-1.3	-1.3	-1.3
Condit. Reinf. active minus inactive responses	4.9	6.4	9.9	1.5	-2.0	-2.7	-2.6	-3.2	-2.9
Condit. Reinf. active-inactive response ratio	2.0	2.3	4.9	0.6	-0.9	-1.4	-1.2	-2.1	-2.2
Condit. Reinf. active responses	3.6	5.0	8.4	0.9	-1.5	-2.3	-2.2	-2.9	-2.9
Condit. Reinf. inactive responses	0.3	0.4	0.9	-0.4	-0.6	-0.6	-0.5	-0.7	-1.0
Condit. Reinf. lever presses	0.8	1.1	3.7	-1.1	0.3	-0.2	-0.1	-1.1	-1.9
Condit. Reinf. lever reinforcers received	3.4	4.8	9.0	0.6	-1.4	-2.1	-2.1	-2.9	-3.0
Conditioned reinforcement - actives	0.2	0.3	0.9	0.4	0.5	0.2	0.2	0.6	0.9
Conditioned reinforcement - inactives	0.0	0.1	0.1	-0.2	-0.1	0.2	0.3	0.3	0.3
Conditioned locomotion	0.1	0.1	0.7	0.3	0.8	-0.3	-0.1	-0.2	-0.1
Patch foraging indifference point 0 sec	0.5	0.9	2.5	-1.6	0.2	0.7	0.1	-0.4	-1.5
Patch foraging indifference point AUC	0.1	0.1	0.2	0.5	-0.4	-0.4	-0.4	-0.4	-0.3
Delay disc. indifference point, 0s delay	1.9	2.1	3.4	-1.7	1.6	1.6	1.8	1.0	0.2
Delay disc. indifference point, 16s delay	0.1	0.1	0.3	-0.5	-0.0	-0.1	0.4	-0.2	-0.5
Delay disc. indifference point, 2s delay	0.8	0.8	1.6	-1.2	1.1	0.4	0.6	-0.5	-1.3
Delay disc. indifference point, 24s delay	0.5	0.6	1.0	-0.5	0.7	0.6	1.0	0.8	0.7
Delay disc. indifference point, 4s delay	0.9	1.0	2.0	-1.4	0.9	0.9	1.3	0.6	-0.1
Delay disc. indifference point, 8s delay	0.1	0.1	0.3	0.1	-0.5	-0.2	-0.1	-0.1	-0.2
Indifference point function ln k	0.4	0.8	2.0	-1.4	0.9	0.8	0.8	0.1	-0.8
Indifference point function log k	0.4	0.8	2.0	-1.4	0.9	0.8	0.8	0.1	-0.8
Patch foraging total patch changes 0 sec	0.5	0.9	2.4	-1.5	0.4	0.6	0.3	-0.4	-1.4
Patch foraging total patch changes 12 sec	0.3	0.4	1.5	-0.3	0.1	-0.4	-0.3	-0.8	-1.2
Patch foraging total patch changes 18 sec	1.2	1.8	3.3	-1.8	1.2	1.8	1.3	1.1	0.1
Patch foraging total patch changes 24 sec	0.0	0.0	0.1	-0.1	-0.3	-0.1	-0.2	-0.1	-0.2
Patch foraging total patch changes 6 sec	0.4	0.6	2.7	-1.6	0.1	0.4	0.3	-0.1	-0.9
Patch foraging time to switch 0 sec	0.3	0.6	2.2	-0.1	-0.2	0.4	0.4	1.0	1.5
Patch foraging water rate 0 sec	0.3	0.7	1.1	0.5	-0.3	-1.0	-1.1	-0.9	-1.0
Patch foraging water rate 12 sec	0.5	1.1	4.3	-0.9	0.1	-0.2	0.0	-1.1	-2.1
Patch foraging water rate 18 sec	0.8	1.3	2.5	0.6	-0.7	-1.3	-0.7	-1.5	-1.6
Patch foraging water rate 24 sec	0.1	0.1	0.5	0.7	-0.3	-0.3	-0.0	0.1	0.3
Patch foraging water rate 6 sec	0.2	0.3	0.6	0.3	0.1	-0.7	-0.3	-0.6	-0.7
Seeking ratio, delayed vs. immediate footshock	1.9	2.4	2.9	1.4	-1.7	-1.7	-1.7	-1.5	-1.1
Distance traveled before self-admin	1.9	2.4	3.3	1.8	-1.5	-1.7	-1.8	-1.5	-0.8
Distance traveled after self-admin	0.1	0.2	0.6	-0.2	0.7	-0.1	0.1	-0.3	-0.5
Extensor digitorum longus weight	2.3	9.1	10.6	-2.7	3.1	3.3	3.2	3.2	2.5
Bone: elastic displacement	0.2	0.3	0.9	-0.0	0.7	-0.1	0.2	-0.6	-0.9
Bone: elastic work	1.6	2.1	2.9	1.7	-1.0	-1.6	-1.4	-1.6	-1.1
Bone: endosteal estimation	3.8	8.4	12.2	3.0	-3.5	-3.2	-3.0	-2.7	-1.6
Bone: endosteal perimeter	3.0	6.3	9.7	2.4	-3.1	-2.5	-3.0	-2.2	-1.2
Epididymis fat weight	0.4	1.5	4.8	2.2	-0.5	-1.4	-1.0	-0.2	1.0
Delta time in closed arm before/after self-admin	0.3	0.3	0.4	-0.6	0.4	0.5	0.4	0.6	0.4
Delta time in open arm before/after self-admin	5.3	5.2	7.5	1.9	-2.7	-2.4	-2.4	-2.4	-1.7
Diff in mean of infusions in LGA sessions	0.4	0.4	1.2	-0.4	-0.6	-0.4	-0.5	-0.8	-1.1
Delay discount exponential model param	0.2	0.2	0.6	0.8	-0.4	-0.3	-0.6	-0.0	0.5
Extinction: sum of active levers before priming	0.6	0.6	1.2	1.1	-0.5	-1.0	-0.9	-0.7	-0.2
Active lever presses in extinction session 6	2.3	2.3	3.4	1.2	-0.8	-1.8	-1.6	-1.9	-1.5
Bone: final force	2.0	3.2	7.1	2.7	-1.6	-2.1	-1.9	-1.1	0.4
Bone: final moment	1.6	2.6	6.2	2.5	-1.3	-1.9	-1.8	-0.8	0.5
Food consumed during 24 hour testing period	0.1	0.2	0.6	0.8	-0.2	-0.7	-0.1	-0.3	0.1
Glucose	0.7	1.1	2.5	0.5	1.3	0.5	0.8	1.1	1.6
Heart weight	0.2	0.3	0.4	0.1	-0.6	-0.6	-0.5	-0.5	-0.7
Delay discount hyperbolic model param	0.2	0.3	0.7	0.8	-0.5	-0.3	-0.6	-0.0	0.5
Intermittent access intake day 1-15 change	0.2	0.5	1.8	-0.5	1.3	0.4	0.7	0.4	0.3
Intermittent access intake escalation	0.4	0.9	2.5	-0.8	1.6	0.7	0.9	0.7	0.5
Intermittent access intake escalation 2	0.0	0.1	0.1	0.3	0.2	-0.3	-0.2	-0.3	-0.1
Intermitt. access day 1 inactive lever presses	1.1	4.3	8.5	-1.5	2.9	2.1	1.9	2.0	1.6
Intermitt. access day 15 inactive lever presses	0.5	1.0	1.4	-0.9	1.1	1.2	1.0	1.0	0.7
Intermitt. access escalation Index	0.4	0.5	1.4	1.2	-0.2	-0.5	-0.3	0.2	1.1
Intermittent access day 1 total infusions	0.8	1.3	2.3	1.5	-0.5	-1.4	-1.2	-1.2	-0.6
Intermittent access day 15 total infusions	0.2	0.3	1.4	0.2	1.2	-0.2	0.3	-0.0	0.2
Intermittent access terminal intake (last 3 days)	0.2	0.3	1.5	0.3	1.2	-0.2	0.2	-0.2	-0.1
Intermittent access total infusions	0.3	0.4	0.9	1.0	0.4	-0.8	-0.4	-0.6	-0.3
Intermittent access day 1 locomotion	0.2	0.2	0.4	0.5	0.1	-0.6	-0.3	-0.6	-0.5
Intermittent access day 15 total locomotion	0.3	0.6	1.0	0.5	-0.1	-1.0	-0.6	-1.0	-0.9
Intermittent access total locomotion	0.2	0.2	0.3	0.4	0.5	-0.5	-0.3	-0.5	-0.4
Intermittent access standard deviation	0.1	0.2	0.9	0.2	1.0	-0.1	0.0	-0.1	-0.2
Left kidney weight	0.1	0.5	0.8	0.9	-0.7	-0.8	-0.2	-0.8	-0.6
Right kidney weight	0.1	0.5	1.1	0.6	-1.0	-0.6	-0.3	-0.7	-0.7
Cocaine induced anxiety	0.2	0.3	0.4	-0.6	-0.3	0.6	0.5	0.7	0.4
Post-drug Anxiety	0.2	0.2	0.5	-0.7	-0.2	0.5	0.4	0.6	0.4
Baseline Anxiety	0.1	0.2	0.4	0.1	-0.6	-0.4	-0.6	-0.3	-0.1
Tail length	7.3	28.4	47.9	6.9	-6.5	-5.7	-5.5	-4.0	-0.9
Length with tail	8.8	38.4	65.8	8.1	-7.2	-6.8	-6.5	-4.8	-1.2
Length without tail	4.3	13.7	19.1	4.4	-3.7	-4.3	-4.1	-3.4	-1.7
Times rat made contact with spout	0.2	0.3	0.7	0.7	-0.0	0.3	0.2	0.4	0.8
Lifetime Intake	0.2	0.2	0.8	0.7	0.9	-0.2	0.1	-0.2	0.2
Liver weight, left	2.7	4.5	8.7	2.9	-2.6	-2.3	-2.2	-1.1	0.5
Liver weight, right	0.8	1.3	2.8	1.7	-1.3	-1.2	-1.0	-1.0	-0.3
Locomotor activity	0.2	0.3	0.6	0.2	-0.3	-0.5	-0.8	-0.6	-0.6
Locomotor testing distance	0.3	0.6	1.5	0.1	-0.3	-0.5	-1.0	-1.0	-1.2
Locomotor testing rearing	0.1	0.2	0.5	0.3	-0.5	-0.4	-0.7	-0.4	-0.3
Locomotion in novel chamber	0.6	0.8	2.0	-1.1	1.4	0.8	0.9	0.3	-0.4
Locomotion in novel chamber post-restriction	0.7	1.2	1.5	-0.9	1.2	1.1	1.2	1.2	0.9
Fecal boli incidents, locomotor time 1	2.1	3.0	5.4	0.4	-2.3	-1.5	-1.8	-1.8	-1.9
Change in fecal boli incidents, locomotor task	0.1	0.1	0.5	-0.1	0.7	0.3	0.4	0.3	0.2
Time >=10cm from walls, locomotor time 1	1.2	1.2	3.6	-1.6	-0.7	0.1	-0.1	-0.9	-1.9
Bouts of movement, locomotor time 1	0.2	0.3	0.8	0.0	-0.5	-0.2	-0.3	-0.6	-0.9
Total resting periods, locomotor time 1	0.2	0.3	0.6	-0.8	0.1	0.5	0.5	-0.1	-0.7
Rest time, locomotor task time 1	0.0	0.0	0.1	0.2	0.3	-0.0	-0.0	0.1	0.3
Distance moved, locomotor task time 1	0.2	0.4	0.9	-0.2	-0.6	-0.4	-0.3	-0.7	-1.0
Vertical activity count, locomotor time 1	0.2	0.4	0.8	-0.5	0.3	0.7	0.5	0.9	0.8
Time >=10cm from walls, locomotor time 2	1.6	2.3	5.7	-0.2	-1.1	-1.3	-0.9	-2.0	-2.4
Bouts of movement, locomotor time 2	0.5	0.9	2.6	-1.6	0.7	0.5	0.8	-0.2	-1.1
Total resting periods, locomotor time 2	0.5	0.8	2.5	-1.6	0.7	0.5	0.8	-0.2	-1.1
Rest time, locomotor task time 2	0.3	0.4	1.0	-0.3	0.5	0.6	0.4	0.9	1.0
Distance moved, locomotor task time 2	0.4	0.5	1.6	-0.1	-0.5	-0.4	-0.3	-0.9	-1.3
Vertical activity count, locomotor time 2	0.2	0.2	0.5	-0.7	0.7	0.4	0.6	0.2	-0.2
Light reinforcement 1	0.7	1.6	6.1	-0.2	2.5	0.8	1.2	0.8	0.9
Light reinforcement 2	0.7	1.1	2.0	0.9	0.2	-1.1	-0.8	-1.4	-1.2
Bone: marrow area	3.6	7.8	11.3	2.9	-3.4	-3.1	-3.0	-2.6	-1.5
Bone: maximum diameter	0.7	1.2	2.0	0.4	-1.4	-1.3	-1.4	-1.0	-0.8
Bone: maximum force	3.0	5.3	10.0	3.2	-2.4	-2.7	-2.5	-1.8	-0.2
Bone: maximum moment	2.5	4.3	8.6	2.9	-2.0	-2.4	-2.2	-1.5	-0.1
Mean time between licks in bursts	0.4	1.1	1.9	-0.2	1.1	1.0	0.9	1.3	1.4
Mean num. licks in bursts	0.1	0.2	0.5	0.5	-0.4	-0.2	-0.2	0.3	0.7
Cd content in liver	0.6	0.6	1.3	1.0	-0.4	-0.9	-1.1	-0.6	-0.1
Co content in liver	0.2	0.2	0.4	-0.3	0.1	0.5	0.3	0.6	0.7
Cu content in liver	0.5	0.5	1.0	1.0	-0.4	-0.8	-0.6	-0.8	-0.6
Fe content in liver	1.6	1.9	2.8	1.4	-1.4	-1.6	-1.7	-1.4	-0.8
K content in liver	0.1	0.1	0.2	-0.3	-0.1	0.5	0.3	0.1	-0.2
Mg content in liver	0.1	0.1	0.4	-0.0	-0.6	-0.0	-0.2	-0.4	-0.5
Mn content in liver	2.0	2.3	3.6	-1.4	1.6	1.9	1.7	1.5	0.8
Na content in liver	0.9	0.9	1.7	0.1	-1.1	-0.8	-0.7	-1.2	-1.3
Rb content in liver	0.8	1.0	2.6	-1.0	-0.8	-0.5	-0.6	-1.0	-1.6
Se content in liver	0.4	0.4	0.8	0.3	0.1	-0.9	-0.6	-0.8	-0.8
Sr content in liver	1.2	1.0	3.9	2.0	0.0	-0.5	-0.7	0.1	1.2
Zn content in liver	0.3	0.3	1.2	1.1	-0.5	-0.5	-0.5	-0.2	0.4
Bone: minimum diameter	0.8	1.5	2.6	1.2	-1.3	-1.6	-1.4	-1.1	-0.6
Time in familiar zone, hab. session 1	0.6	0.6	1.1	-0.4	0.0	0.9	0.7	1.0	1.1
Time in novel zone, hab. session 1	0.4	0.4	0.9	0.3	0.0	-0.5	-0.6	-0.9	-0.9
Total zone transitions, hab. session 1	0.3	0.4	1.4	-1.2	-0.5	0.4	0.4	-0.0	-0.6
Total locomotion distance, hab. session 1	0.6	0.9	2.1	0.2	-0.8	-0.7	-0.7	-1.3	-1.4
Locomotion velocity, hab. session 1	0.7	1.0	1.4	0.8	-1.0	-1.1	-1.0	-1.2	-1.0
Time in familiar zone, hab. session 2	0.8	0.8	1.6	-0.5	1.1	1.2	1.3	0.6	0.3
Time in novel zone, hab. session 2	0.5	0.5	1.2	0.5	-0.6	-1.1	-1.0	-0.5	-0.2
Total zone transitions, hab. session 2	0.2	0.2	0.7	0.2	-0.5	0.1	0.1	0.5	0.8
Total locomotion distance, hab. session 2	0.5	0.6	2.1	1.4	-0.8	-0.6	-0.5	-0.2	0.6
Locomotion velocity, hab. session 2	0.5	0.7	2.2	1.5	-1.0	-0.6	-0.6	-0.1	0.7
Novel to familiar place preference ratio	2.6	2.9	5.2	2.3	-1.2	-2.1	-1.5	-1.8	-0.8
Novelty place preference	2.5	2.7	4.7	2.2	-1.3	-2.1	-1.5	-1.7	-0.8
Time in novel zone, NPP test	2.2	2.4	4.1	2.0	-1.1	-2.0	-1.3	-1.7	-0.8
Total zone transitions, NPP test	0.1	0.1	0.2	-0.4	0.3	0.3	0.5	0.3	0.2
Total locomotion distance, NPP test	0.1	0.1	0.2	0.4	0.4	-0.2	0.0	-0.4	-0.4
Locomotion velocity, NPP test	0.1	0.1	0.2	0.4	0.4	-0.1	0.1	-0.2	-0.1
Intraocular pressure	2.7	3.8	6.2	-1.8	2.2	2.2	2.5	1.7	1.0
Delta distance traveled before/after self-admin	0.9	1.0	2.1	-1.1	1.4	0.8	1.1	0.7	0.3
Delta ambulatory time before/after self-admin	0.4	0.5	1.9	-0.7	1.4	0.4	0.8	0.3	-0.0
Parametrial fat weight	0.4	0.8	1.8	0.3	1.0	0.6	0.8	1.1	1.4
Pavlov. Cond. lever latency	2.0	2.5	3.8	-0.8	0.9	1.7	1.8	1.9	1.9
Pavlov. Cond. magazine entry latency	1.1	1.4	3.6	0.3	-0.7	-1.1	-0.5	-1.6	-1.9
Pavlov. Cond. change in total contacts	1.3	1.4	4.5	-0.1	-0.3	-0.8	-0.9	-1.6	-2.1
Pavlov. Cond. index score	1.4	1.8	3.3	0.8	-0.7	-1.5	-1.1	-1.8	-1.8
Pavlov. Cond. latency score	2.1	2.7	4.4	0.8	-1.0	-1.8	-1.5	-2.1	-2.1
Pavlov. Cond. lever contacts	1.5	1.8	3.2	0.6	-0.6	-1.4	-1.3	-1.8	-1.8
Pavlov. Cond. magazine entry number	1.1	1.4	2.7	-0.8	0.7	1.2	0.7	1.6	1.6
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.3	1.1	-0.8	-1.1	-0.9	-0.6	0.0
Pavlov. Cond. lever-magazine prob. diff.	1.1	1.4	3.2	0.5	-0.5	-1.2	-0.8	-1.6	-1.8
Pavlov. Cond. response bias	0.8	1.0	2.0	0.7	-0.5	-0.9	-0.6	-1.4	-1.4
Pavlov. Cond. lever latency	0.5	0.7	1.8	1.3	-0.4	-0.8	-0.6	0.4	1.2
Pavlov. Cond. magazine entry latency	0.5	0.6	1.2	-0.9	0.1	1.1	0.9	0.7	0.3
Pavlov. Cond. change in total contacts	0.5	0.8	2.9	-1.1	-0.1	0.3	0.1	-0.8	-1.7
Pavlov. Cond. index score	0.4	0.5	1.3	-1.1	0.1	0.7	0.6	-0.3	-1.0
Pavlov. Cond. latency score	0.3	0.4	0.9	-0.9	0.1	0.6	0.5	-0.3	-0.9
Pavlov. Cond. lever contacts	0.7	0.9	3.0	-1.3	0.2	0.5	0.3	-0.8	-1.7
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	0.0	0.5	-0.1	0.0	0.4	0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.7	-0.2	0.3	-0.8	-0.3	-0.5	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.6	1.5	-1.2	0.1	0.7	0.5	-0.3	-1.1
Pavlov. Cond. response bias	0.4	0.5	1.8	-0.8	-0.4	0.3	0.0	-0.7	-1.3
Time in closed arm before self-admin	2.3	3.0	3.6	1.9	-1.9	-1.9	-1.8	-1.7	-0.9
Time in closed arm after self-admin	0.8	0.9	2.2	-0.0	-0.7	-0.8	-0.9	-1.1	-1.5
Time in open arm before self-admin	5.2	5.7	9.8	-1.5	3.1	2.3	2.2	2.6	2.3
Time in open arm after self-admin	0.4	0.4	0.7	0.6	-0.8	-0.8	-0.7	-0.6	-0.2
Bone: periosteal estimation	2.5	5.3	7.1	2.3	-2.7	-2.6	-2.6	-2.1	-1.2
Bone: periosteal perimeter	1.7	3.0	4.5	1.7	-1.8	-1.8	-2.1	-1.7	-1.0
Bone: post-yield work	0.8	1.2	2.1	1.4	-1.2	-1.2	-1.2	-0.7	0.1
Progressive ratio test 1 active lever presses	0.3	0.3	0.6	-0.2	0.8	0.5	0.7	0.5	0.5
Progressive ratio test 1 breakpoint	0.1	0.2	0.3	-0.1	0.6	0.4	0.5	0.3	0.3
Progressive ratio test 1 inactive lever presses	2.8	4.0	7.1	-0.7	2.7	1.8	1.9	2.2	2.3
Progressive ratio test 2 active lever presses	0.1	0.1	0.2	0.3	0.4	-0.1	0.2	0.1	0.4
Progressive ratio test 2 breakpoint	0.1	0.1	0.2	0.2	0.5	-0.0	0.2	0.1	0.4
Progressive ratio test 2 inactive lever presses	0.2	0.4	1.2	0.2	1.1	0.1	0.6	0.4	0.7
Incentive Sensitization - Responses	0.2	0.3	0.5	0.6	-0.7	-0.6	-0.5	-0.3	0.1
Incentive Sensitization - Breakpoint	0.2	0.2	0.4	0.6	-0.6	-0.6	-0.4	-0.2	0.2
Sum of active levers in priming session hrs 5-6	2.4	2.3	3.4	1.6	-1.2	-1.8	-1.8	-1.5	-0.8
Progressive ratio	1.1	1.7	2.9	-1.0	0.8	1.7	1.5	1.4	1.2
Food seeking constrained by brief footshock	0.1	0.1	0.3	0.0	0.1	0.4	0.1	0.5	0.5
Seeking ratio, punishment vs. effort	1.0	1.4	2.1	1.0	-1.3	-1.5	-1.4	-1.1	-0.7
Retroperitoneal fat weight	0.2	1.0	2.8	1.7	0.4	-0.7	-0.4	0.5	1.5
Reaction time number correct	0.2	0.4	1.0	-1.0	0.7	0.5	0.8	0.3	-0.2
Reaction time mean minus median	0.6	1.4	5.5	2.3	-0.5	-1.2	-0.9	-0.6	0.7
Reaction time mean minus median AUC	0.4	0.9	3.7	1.9	-0.4	-1.0	-0.6	-0.5	0.3
Reaction time num false alarms	3.1	4.4	5.5	-1.6	2.3	2.3	2.3	2.2	1.6
Reaction time num false alarms AUC	3.4	5.3	7.0	-1.6	2.5	2.6	2.6	2.5	1.9
Reaction time trials correct on left	0.2	0.4	1.0	-1.0	0.7	0.5	0.8	0.3	-0.2
Reaction time trials on left	0.2	0.4	0.8	-0.9	0.7	0.4	0.8	0.3	-0.2
Reaction time mean	1.7	2.7	7.9	2.8	-1.3	-1.7	-1.5	-1.1	0.4
Reaction time mean AUC	1.4	2.3	7.5	2.7	-1.0	-1.5	-1.3	-0.9	0.6
Median of all reaction times	1.7	2.4	6.3	2.5	-1.4	-1.6	-1.5	-1.0	0.2
Reaction time omissions	0.6	0.9	3.9	2.0	-0.3	-0.8	-0.4	-0.6	0.4
Reaction time false alarm rate	2.0	2.8	3.9	-1.0	1.7	2.0	1.7	1.9	1.6
Reaction time premature initiation rate	1.0	1.4	3.4	-1.6	1.2	0.6	0.6	-0.6	-1.8
Reaction time premature initiations	1.0	1.8	3.8	-2.0	1.5	0.8	1.0	-0.3	-1.7
Std. dev. reaction times	1.3	2.5	6.9	2.6	-1.2	-1.7	-1.5	-1.2	0.1
Reaction time trials completed	0.2	0.4	0.8	-0.9	0.7	0.4	0.8	0.3	-0.2
Reaction time trials AUC	0.2	0.4	0.9	-0.9	0.7	0.4	0.8	0.4	-0.1
Run reversals in cocaine runway, females	0.5	0.5	0.9	-0.3	-0.3	0.7	0.9	0.8	1.0
Run reversals in cocaine runway, males	0.4	0.4	1.6	-0.4	0.2	-0.2	-0.0	-0.8	-1.3
Latency to leave start box in cocaine runway	5.3	6.0	9.1	-2.5	2.7	2.6	3.0	2.2	1.3
Latency to leave start box in cocaine runway, F	5.3	6.1	7.9	-2.3	2.6	2.8	2.8	2.5	1.7
Latency to leave start box in cocaine runway, M	1.6	1.5	2.8	-1.6	1.2	1.2	1.7	0.8	0.0
Std. dev. time between licks in bursts	2.0	2.7	5.5	-1.0	2.4	1.6	2.0	1.4	1.0
Total sessions with >9 infusions	0.9	1.1	2.7	-0.3	1.7	0.9	1.2	0.9	0.9
Short access day 1 total inactive lever presses	0.2	0.3	1.2	0.0	1.1	-0.3	-0.0	-0.3	-0.4
Short access day 10 total inactive lever presses	0.1	0.1	0.7	-0.2	0.8	-0.0	-0.2	0.1	0.1
Short access day 1 total infusions	0.3	0.4	1.0	0.8	1.0	-0.0	0.3	0.2	0.6
Short access day 10 total infusions	0.3	0.4	1.0	0.8	1.0	-0.5	0.2	-0.6	-0.4
Short access total infusions	0.3	0.4	1.9	0.3	1.4	0.2	0.7	0.0	0.2
Short access day 1 locomotion	0.5	0.6	1.3	-0.1	1.1	0.7	0.8	0.7	0.8
Short access day 10 total locomotion	0.3	0.5	1.0	-0.7	1.0	0.2	0.4	-0.4	-1.0
Short access total locomotion	0.7	0.8	1.9	-0.3	1.4	0.8	1.0	0.8	0.8
One hour access (0.3 mA shock)	0.6	0.7	1.3	1.1	0.2	-1.1	-0.5	-1.1	-0.7
Compulsive drug intake	0.7	0.8	1.2	-0.6	0.7	1.0	1.0	1.1	1.0
One hour access (shock baseline)	1.0	1.5	2.7	1.1	-0.0	-1.5	-1.0	-1.6	-1.3
Social response proportion	4.5	5.1	6.8	2.2	-2.2	-2.6	-2.5	-2.4	-1.6
Social responses	1.5	1.9	3.3	1.8	-0.9	-1.8	-1.5	-1.3	-0.5
Social time	0.5	0.7	1.6	1.3	-0.3	-1.2	-0.7	-0.6	-0.0
Soleus weight	0.2	0.5	0.8	0.4	-0.6	-0.8	-0.5	-0.9	-0.9
Bone: stiffness	2.7	4.4	8.5	2.9	-2.4	-2.3	-2.3	-1.1	0.5
Tibialis anterior weight	0.5	1.6	2.0	-1.2	1.1	1.4	1.2	1.4	1.0
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.7	0.6	-0.3	-0.2	-0.1	0.4	0.8
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.3	0.3	-0.5	0.0	-0.3	0.2	0.5
Time to tail flick, test, before self-admin	0.7	0.7	1.3	-0.9	1.1	0.9	1.0	0.6	0.1
Time to tail flick, test, after self-admin	0.7	0.8	1.2	-0.5	0.9	0.8	0.8	1.1	1.0
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.2	-0.3	0.4	0.5	0.2	0.2	0.1
Delta time to tail flick, test, before/after SA	0.1	0.1	0.1	-0.1	0.2	0.2	0.2	0.3	0.4
Tibia length	3.7	10.1	19.2	4.4	-4.0	-3.2	-3.4	-2.0	0.1
Ambulatory time before self-admin	1.1	1.7	2.6	1.6	-1.1	-1.5	-1.6	-1.1	-0.4
Ambulatory time after self-admin	0.2	0.3	1.3	-0.2	1.1	-0.1	0.1	-0.3	-0.4
Bone: tissue strength	1.1	1.1	3.9	2.0	-0.6	-0.8	-0.4	0.1	1.3
Total heroin consumption	0.2	0.3	0.5	0.7	-0.3	-0.6	-0.5	-0.6	-0.2
Bone: trabecular number	2.5	4.1	8.5	1.8	-2.9	-1.8	-2.2	-1.9	-1.1
Bone: trabecular spacing	0.4	0.5	0.9	-0.9	0.8	0.8	0.8	0.7	0.1
Bone: trabecular thickness	1.8	2.2	2.9	0.9	-1.7	-1.5	-1.6	-1.6	-1.3
Bone: trabecular tissue density	0.2	0.3	1.2	0.3	0.5	0.0	-0.2	0.7	1.1
Water consumed over 24 hours	0.3	0.4	1.3	0.1	0.4	0.6	1.1	0.3	0.3
Number of responses in last shaping day	1.3	1.4	2.7	-0.3	0.9	1.2	1.1	1.5	1.7