Ccdc134

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	mRNA stability	Ccdc134	0.03	0.02	1.6e-03	0.01	0.01	0.01	0.01	1.7e-02	1.3e-02	2.5e-02	5.8e-02
2	IC	intron excision ratio	chr7_115526847_115528239	0.17	0.09	1.5e-07	0.15	0.14	0.14	0.15	6.5e-07	1.5e-06	2.1e-06	5.2e-07
3	IC	intron excision ratio	chr7_115522869_115523422	0.17	0.09	2.1e-07	0.15	0.14	0.14	0.15	1.0e-06	1.3e-06	1.4e-06	5.2e-07
4	Brain	intron excision ratio	chr7_115522869_115523422	0.17	0.07	1.1e-16	0.17	0.14	0.15	0.15	2.4e-15	9.6e-13	7.1e-14	5.2e-14
5	Brain	intron excision ratio	chr7_115526847_115528239	0.16	0.07	0.0e+00	0.18	0.15	0.15	0.17	2.7e-16	6.1e-14	1.3e-13	1.6e-15
6	BLA	gene expression	Ccdc134	0.2	0.1	3.7e-05	0.08	0.04	0.04	0.05	5.2e-05	2.1e-03	2.9e-03	1.1e-03
7	Liver	gene expression	Ccdc134	0.19	0.08	0.0e+00	0.18	0.15	0.16	0.17	1.1e-19	2.3e-16	1.0e-17	7.6e-19
8	Adipose	gene expression	Ccdc134	0.24	0.1	0.0e+00	0.14	0.14	0.14	0.15	2.2e-15	7.8e-16	1.3e-15	3.9e-16
9	pVTA	gene expression	Ccdc134	0.17	0.1	5.8e-04	0.03	0.04	0.01	0.02	1.0e-03	7.0e-04	6.1e-02	1.1e-02
10	Brain	gene expression	Ccdc134	0.18	0.08	9.5e-13	0.11	0.13	0.13	0.13	4.4e-10	1.7e-12	4.2e-12	8.9e-12
11	PL	gene expression	Ccdc134	0.05	0.03	2.1e-04	0.01	0.04	0.03	0.02	1.3e-02	5.8e-05	4.4e-04	9.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.3	0.4	0.6	0.8	-0.8	0.8	0.7	-0.7	0.6	0.7	0.5	0.3	0.5	0.7
Area under the delay curve	0.2	0.2	0.6	0.6	-0.3	0.3	0.3	-0.3	0.6	0.6	0.8	0.6	0.2	0.2
BMI with tail	0.6	2.0	3.9	-1.9	2.0	-2.0	-2.0	2.0	-0.8	-0.6	-0.4	1.0	0.1	0.3
BMI without tail	0.0	0.1	0.5	-0.4	0.2	-0.2	-0.1	0.1	-0.4	-0.2	-0.7	-0.4	-0.1	-0.5
Body weight	0.7	3.1	6.2	-2.5	2.3	-2.3	-2.3	2.3	-1.7	-1.5	-1.1	0.1	-0.6	-0.1
Weight adjusted by age	0.9	1.3	3.2	-0.2	-0.1	0.1	0.1	-0.1	-1.3	-1.8	-1.6	-1.7	-1.5	-1.5
Bone surface	0.4	0.8	3.2	0.4	-0.7	0.7	0.5	-0.5	-0.5	-0.6	-1.2	-1.8	-1.1	-0.5
Bone volume	0.1	0.2	0.5	0.1	-0.3	0.3	0.1	-0.1	-0.3	-0.3	-0.7	-0.7	-0.6	-0.1
Breakpoint value in progressive ratio session	0.3	0.3	0.8	0.0	0.1	-0.1	-0.1	0.1	0.9	0.6	0.9	0.4	0.9	0.8
Number of licking bursts	0.2	0.3	0.7	0.8	-0.8	0.8	0.8	-0.8	0.4	0.2	0.1	-0.7	0.1	-0.1
Context. condit. distance diff. score	5.2	6.3	9.9	-3.1	3.1	-3.1	-3.1	3.1	-2.5	-2.5	-1.9	-0.1	-1.5	-1.2
Locomotion velocity, session 1	1.5	1.6	5.7	-0.3	-0.1	0.1	0.2	-0.2	-1.4	-1.6	-1.6	-2.4	-1.8	-1.3
Locomotion distance, session 1	1.7	2.1	3.9	1.8	-2.0	2.0	2.0	-2.0	0.3	0.1	-0.3	-1.7	-0.7	-0.9
Locomotion velocity, session 2	0.4	0.5	1.2	-0.7	0.6	-0.6	-0.4	0.4	-0.8	-0.8	-0.8	-0.8	-1.1	-0.5
Locomotion distance, session 2	2.2	3.1	4.5	2.1	-2.0	2.0	2.1	-2.1	2.0	1.8	1.7	0.2	1.2	1.2
Locomotion velocity, session 3	1.2	1.4	3.1	-0.5	0.4	-0.4	-0.5	0.5	-1.6	-1.4	-1.6	-1.4	-1.8	-1.3
Locomotion distance, session 3	1.0	1.1	1.9	1.2	-1.2	1.2	1.1	-1.1	-0.4	-0.5	-0.8	-1.3	-0.9	-1.4
Stereotopy head waving bouts, day 3	0.7	0.8	1.3	-1.1	1.1	-1.1	-1.0	1.0	-1.0	-0.8	-0.7	-0.4	-0.8	-0.0
Stereotopy head waving duration, day 3	3.0	3.6	6.2	-2.5	2.3	-2.3	-2.1	2.1	-2.1	-1.8	-1.7	-0.7	-1.6	-0.6
Locomotion velocity, session 7	0.3	0.3	0.6	-0.2	0.3	-0.3	-0.4	0.4	-0.7	-0.7	-0.6	-0.0	-0.8	-0.7
Locomotion distance, session 7	0.5	0.6	2.5	0.6	-0.2	0.2	0.0	-0.0	0.9	0.7	1.2	1.6	0.7	0.8
Stereotopy head waving bouts, day 7	5.2	5.8	10.8	-2.0	1.5	-1.5	-1.5	1.5	-3.2	-3.0	-3.3	-2.6	-3.0	-2.3
Stereotopy head waving duration, day 7	3.6	4.3	8.1	-1.9	1.4	-1.4	-1.4	1.4	-2.8	-2.5	-2.9	-1.9	-2.4	-2.0
Locomotion velocity, session 8	1.8	2.2	4.1	-2.0	1.8	-1.8	-1.7	1.7	-1.6	-1.5	-1.2	-0.9	-0.8	-0.3
Locomotion distance, session 8	0.8	1.1	1.7	-1.2	1.3	-1.3	-1.2	1.2	-1.1	-1.1	-1.0	-0.3	-0.9	-0.7
Degree of sensitization distance	2.5	2.6	6.5	-1.4	1.9	-1.9	-1.8	1.8	0.6	0.6	1.3	2.6	1.3	1.7
Degree of sensitization stereotypy	3.9	4.2	8.0	-1.7	1.2	-1.2	-1.2	1.2	-2.8	-2.6	-2.8	-2.3	-2.4	-2.1
Conditioned locomotion	0.8	1.0	1.5	-0.9	1.1	-1.1	-0.9	0.9	-1.2	-0.9	-1.0	0.1	-1.1	-1.1
Cocaine response after cond. corrected	0.1	0.2	0.3	-0.3	0.1	-0.1	-0.3	0.3	-0.5	-0.5	-0.5	-0.4	-0.5	-0.5
Cocaine response after cond. not corrected	0.2	0.2	0.5	-0.3	0.2	-0.2	-0.3	0.3	-0.5	-0.4	-0.7	-0.5	-0.7	-0.7
Cocaine response before conditioning	0.0	0.1	0.2	0.2	-0.0	0.0	0.3	-0.3	0.3	0.5	-0.2	0.0	-0.1	-0.1
Saline control response	0.6	0.8	2.0	-0.6	0.7	-0.7	-0.3	0.3	-0.8	-0.6	-1.3	-1.2	-1.4	-1.1
Bone: connectivity density	0.1	0.1	0.3	0.4	-0.5	0.5	0.4	-0.4	0.4	0.4	0.2	0.1	0.2	0.6
Bone: cortical apparent density	0.5	0.7	1.7	1.3	-1.1	1.1	1.0	-1.0	0.7	0.8	0.5	0.0	0.3	0.1
Bone: cortical area	1.2	1.8	3.5	-1.8	1.6	-1.6	-1.9	1.9	-1.3	-1.2	-0.8	-0.1	-0.5	-0.1
Bone: cortical porosity	0.2	0.2	0.4	-0.6	0.6	-0.6	-0.5	0.5	-0.1	0.1	-0.3	0.4	-0.1	-0.1
Bone: cortical porosity	1.0	1.1	2.1	-1.5	1.3	-1.3	-1.2	1.2	-1.0	-0.8	-1.0	-0.1	-0.8	-0.5
Bone: cortical thickness	0.6	1.1	2.3	-0.5	0.7	-0.7	-0.9	0.9	0.7	0.6	1.2	1.5	1.5	1.4
Bone: cortical thickness	0.9	1.0	2.3	-0.6	0.7	-0.7	-0.7	0.7	0.7	0.5	1.4	1.4	1.5	1.4
Bone: cortical tissue density	0.5	0.6	1.6	1.3	-1.1	1.1	0.9	-0.9	0.7	0.8	0.5	-0.0	0.2	0.1
Condit. Reinf. active minus inactive responses	0.2	0.2	0.7	0.4	-0.3	0.3	0.1	-0.1	0.6	0.5	0.7	0.5	0.4	0.8
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.6	-0.6	0.6	-0.6	-0.8	0.8	-0.6	-0.7	-0.4	-0.2	-0.5	-0.0
Condit. Reinf. active responses	1.1	1.3	2.1	1.3	-1.0	1.0	1.1	-1.1	1.4	1.5	1.2	0.8	0.9	1.0
Condit. Reinf. inactive responses	2.1	2.6	4.0	2.0	-1.6	1.6	1.9	-1.9	1.8	2.0	1.3	1.0	1.2	0.8
Incentive salience index mean	0.6	0.8	1.4	0.8	-0.5	0.5	0.5	-0.5	1.2	1.1	1.2	1.0	0.8	1.1
Condit. Reinf. lever presses	0.7	1.0	1.8	1.2	-0.8	0.9	1.0	-1.0	1.3	1.3	1.0	0.9	0.6	0.8
Condit. Reinf. active minus inactive responses	0.4	0.5	2.2	-0.0	-0.0	0.0	-0.4	0.4	0.7	0.4	1.0	0.5	1.0	1.5
Condit. Reinf. active-inactive response ratio	0.6	0.7	3.1	-0.1	0.1	-0.1	-0.4	0.4	0.8	0.4	1.2	0.6	1.1	1.7
Condit. Reinf. active responses	0.4	0.5	1.4	-0.9	0.8	-0.8	-1.2	1.2	-0.4	-0.6	-0.0	-0.1	-0.0	0.6
Condit. Reinf. inactive responses	0.9	1.1	1.8	-1.1	1.2	-1.2	-1.3	1.3	-1.2	-1.1	-0.8	-0.2	-1.0	-0.6
Condit. Reinf. lever presses	0.3	0.4	1.0	0.6	-0.7	0.7	0.3	-0.3	0.7	0.7	0.7	0.1	0.7	1.0
Condit. Reinf. lever reinforcers received	0.2	0.3	0.8	-0.6	0.5	-0.5	-0.9	0.9	-0.1	-0.2	0.3	0.2	0.2	0.9
Conditioned reinforcement - actives	0.3	0.6	1.5	-0.8	0.9	-0.9	-1.2	1.2	-0.5	-0.9	0.1	0.5	0.0	0.2
Conditioned reinforcement - inactives	0.9	1.3	3.6	-0.1	0.3	-0.3	-0.5	0.5	1.3	0.7	1.7	1.5	1.8	1.9
Conditioned locomotion	1.2	1.5	2.8	-1.4	1.7	-1.7	-1.7	1.7	-0.1	0.2	0.5	1.5	0.5	0.9
Patch foraging indifference point 0 sec	0.3	0.6	1.1	0.7	-0.7	0.7	0.6	-0.6	1.0	1.1	0.8	0.2	0.9	1.1
Patch foraging indifference point AUC	0.2	0.3	0.8	0.7	-0.7	0.7	0.6	-0.6	0.2	-0.1	0.1	-0.9	-0.4	-0.3
Delay disc. indifference point, 0s delay	0.7	0.7	1.7	-1.1	1.3	-1.3	-1.1	1.1	-0.5	0.0	-0.1	1.0	-0.1	0.1
Delay disc. indifference point, 16s delay	0.7	0.8	1.7	1.3	-1.1	1.1	1.0	-1.0	1.1	0.7	0.7	0.2	0.5	0.4
Delay disc. indifference point, 2s delay	0.2	0.2	1.0	-0.0	0.4	-0.4	-0.3	0.3	0.2	0.4	0.5	1.0	0.1	0.1
Delay disc. indifference point, 24s delay	0.3	0.4	1.4	0.5	-0.5	0.5	0.3	-0.3	-0.5	-0.5	-0.3	-1.2	-0.9	-0.8
Delay disc. indifference point, 4s delay	0.4	0.4	1.3	0.0	0.2	-0.2	-0.1	0.1	0.6	0.5	1.1	0.8	0.8	1.1
Delay disc. indifference point, 8s delay	0.7	0.8	1.6	1.1	-0.8	0.8	0.9	-0.9	1.0	1.3	1.1	0.8	0.6	0.3
Indifference point function ln k	0.4	0.7	1.4	-1.2	1.0	-1.0	-1.1	1.1	-0.8	-0.8	-0.7	0.2	-0.4	-0.1
Indifference point function log k	0.4	0.7	1.4	-1.2	1.0	-1.0	-1.1	1.1	-0.8	-0.8	-0.7	0.2	-0.4	-0.1
Patch foraging total patch changes 0 sec	0.4	0.8	1.3	0.9	-0.9	0.9	0.8	-0.8	1.1	1.1	0.8	0.2	1.0	1.0
Patch foraging total patch changes 12 sec	0.0	0.0	0.3	0.0	0.0	-0.0	-0.1	0.1	0.1	0.2	0.1	-0.2	-0.1	0.5
Patch foraging total patch changes 18 sec	0.2	0.4	1.2	0.3	-0.3	0.3	0.3	-0.3	0.8	0.7	0.8	0.3	0.8	1.1
Patch foraging total patch changes 24 sec	0.1	0.2	0.5	0.6	-0.7	0.7	0.6	-0.6	0.3	0.3	0.1	-0.6	-0.2	-0.1
Patch foraging total patch changes 6 sec	0.2	0.3	0.6	0.4	-0.4	0.4	0.4	-0.4	0.7	0.7	0.5	-0.5	0.6	0.8
Patch foraging time to switch 0 sec	0.0	0.1	0.2	0.2	-0.1	0.1	0.2	-0.2	-0.1	0.2	-0.4	0.5	-0.4	-0.2
Patch foraging water rate 0 sec	0.2	0.4	1.2	0.1	-0.4	0.4	0.3	-0.3	0.8	0.7	0.8	-0.4	1.1	0.8
Patch foraging water rate 12 sec	0.2	0.4	1.1	0.6	-0.9	0.9	0.8	-0.8	-0.0	-0.0	-0.3	-1.1	0.0	-0.1
Patch foraging water rate 18 sec	0.7	1.1	2.4	1.2	-1.5	1.5	1.3	-1.3	0.5	0.4	-0.0	-1.5	0.2	0.2
Patch foraging water rate 24 sec	0.1	0.1	0.5	-0.4	-0.1	0.1	-0.1	0.1	-0.0	-0.1	0.0	-0.7	0.4	0.7
Patch foraging water rate 6 sec	0.8	1.1	2.9	0.9	-1.4	1.4	1.2	-1.2	0.1	-0.0	-0.6	-1.7	-0.8	-0.7
Seeking ratio, delayed vs. immediate footshock	3.1	3.7	5.8	2.4	-2.1	2.1	2.1	-2.1	2.3	2.4	1.7	0.8	1.4	1.0
Distance traveled before self-admin	1.5	2.0	4.7	0.7	-0.2	0.2	0.2	-0.2	2.0	1.6	1.9	2.2	1.9	1.7
Distance traveled after self-admin	0.3	0.4	1.6	0.1	-0.0	0.0	-0.1	0.1	0.7	-0.0	0.7	0.6	1.1	1.3
Extensor digitorum longus weight	0.1	0.4	1.0	0.5	-0.7	0.7	1.0	-1.0	0.2	0.3	-0.3	-0.6	0.2	-0.3
Bone: elastic displacement	0.8	0.9	3.5	-0.5	0.1	-0.1	-0.0	0.0	-1.1	-1.1	-1.3	-1.9	-1.2	-1.2
Bone: elastic work	1.7	2.2	4.5	-2.1	1.7	-1.7	-1.9	1.9	-1.5	-1.5	-1.2	-0.7	-0.8	-0.2
Bone: endosteal estimation	1.8	4.0	8.4	-1.6	1.1	-1.1	-1.1	1.1	-2.4	-2.2	-2.9	-2.5	-2.7	-1.9
Bone: endosteal perimeter	2.8	6.0	10.4	-2.2	1.8	-1.8	-1.8	1.8	-3.2	-3.0	-3.2	-2.1	-3.1	-2.4
Epididymis fat weight	1.4	4.7	9.5	-2.8	3.1	-3.1	-3.0	3.0	-1.5	-1.4	-0.5	1.5	-0.8	0.1
Delta time in closed arm before/after self-admin	0.5	0.5	1.4	-0.3	0.7	-0.7	-0.7	0.7	0.7	0.4	0.9	1.2	0.5	0.5
Delta time in open arm before/after self-admin	1.1	1.1	2.7	0.1	-0.4	0.4	0.4	-0.4	-1.4	-1.2	-1.4	-1.6	-1.2	-1.2
Diff in mean of infusions in LGA sessions	0.0	0.1	0.1	-0.3	0.3	-0.3	-0.3	0.3	0.1	-0.1	0.2	-0.2	0.1	0.3
Delay discount exponential model param	0.2	0.2	0.6	-0.6	0.3	-0.3	-0.4	0.4	-0.5	-0.5	-0.7	-0.5	-0.2	-0.2
Extinction: sum of active levers before priming	0.5	0.5	1.2	-1.0	1.1	-1.1	-1.1	1.1	-0.0	-0.3	-0.0	0.2	0.0	0.2
Active lever presses in extinction session 6	0.2	0.2	0.4	-0.6	0.7	-0.7	-0.5	0.5	0.1	0.0	-0.2	-0.1	-0.1	-0.1
Bone: final force	0.8	1.3	2.7	-1.5	1.5	-1.5	-1.7	1.7	-0.4	-0.5	-0.1	0.8	0.3	0.9
Bone: final moment	0.9	1.4	2.8	-1.6	1.6	-1.6	-1.7	1.7	-0.6	-0.7	-0.2	0.5	0.2	0.9
Food consumed during 24 hour testing period	0.9	1.2	2.5	-1.4	1.5	-1.5	-1.6	1.6	-0.6	-0.5	0.1	0.8	0.3	0.6
Glucose	0.3	0.4	1.7	0.3	0.0	-0.0	0.2	-0.2	0.5	0.9	0.6	1.3	0.8	0.8
Heart weight	5.2	8.1	16.4	-4.1	4.0	-4.0	-3.7	3.7	-2.4	-2.0	-1.5	0.4	-0.7	-0.2
Delay discount hyperbolic model param	0.2	0.2	0.6	-0.4	0.1	-0.1	-0.2	0.2	-0.5	-0.5	-0.8	-0.6	-0.2	-0.3
Intermittent access intake day 1-15 change	0.2	0.5	0.8	0.7	-0.8	0.8	0.9	-0.9	0.7	0.3	0.7	0.6	0.7	0.5
Intermittent access intake escalation	0.2	0.5	1.0	0.8	-1.0	1.0	1.0	-1.0	0.5	0.2	0.5	0.3	0.5	0.2
Intermittent access intake escalation 2	0.5	0.5	1.1	0.9	-0.9	0.9	1.0	-1.0	0.5	0.4	0.4	0.5	0.5	0.1
Intermitt. access day 1 inactive lever presses	0.6	2.2	4.9	-0.7	1.0	-1.0	-0.9	0.9	1.4	1.2	1.9	2.1	2.0	2.2
Intermitt. access day 15 inactive lever presses	1.6	3.3	7.2	-0.2	0.6	-0.6	-0.5	0.5	2.0	2.2	2.6	2.4	2.5	2.7
Intermitt. access escalation Index	0.2	0.2	0.7	0.4	-0.5	0.5	0.5	-0.5	0.6	0.8	0.4	0.1	0.4	0.5
Intermittent access day 1 total infusions	0.5	0.8	1.6	-0.9	1.1	-1.1	-1.2	1.2	0.0	-0.4	0.7	1.1	0.6	1.0
Intermittent access day 15 total infusions	0.1	0.1	0.3	0.2	-0.2	0.2	0.1	-0.1	0.3	-0.1	0.5	0.6	0.4	0.4
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.3	0.2	-0.1	0.1	0.0	-0.0	-0.0	-0.4	0.2	0.6	0.0	-0.0
Intermittent access total infusions	0.2	0.3	0.9	-0.3	0.5	-0.5	-0.6	0.6	0.0	-0.4	0.4	0.9	0.3	0.5
Intermittent access day 1 locomotion	0.7	0.9	2.5	-0.2	0.5	-0.5	-0.5	0.5	1.0	0.7	1.2	1.6	1.2	1.3
Intermittent access day 15 total locomotion	0.1	0.2	0.6	-0.3	0.2	-0.2	-0.3	0.3	0.1	-0.4	0.4	0.8	0.5	0.6
Intermittent access total locomotion	0.4	0.4	1.5	-0.3	0.4	-0.4	-0.6	0.6	0.5	-0.2	0.8	1.2	0.8	0.9
Intermittent access standard deviation	0.5	1.1	5.2	-0.5	0.8	-0.8	-0.8	0.8	0.5	0.6	1.0	2.3	1.2	1.2
Left kidney weight	7.4	34.3	66.9	-8.2	7.9	-7.9	-7.5	7.5	-5.3	-5.1	-3.4	-0.1	-2.6	-0.3
Right kidney weight	7.6	34.8	69.6	-8.3	8.3	-8.3	-7.9	7.9	-4.6	-4.4	-2.2	1.3	-1.4	0.7
Cocaine induced anxiety	0.3	0.5	1.2	-0.6	0.5	-0.5	-0.5	0.5	0.1	0.0	1.1	0.7	1.0	1.0
Post-drug Anxiety	0.1	0.1	0.2	0.2	-0.5	0.5	0.5	-0.5	-0.2	-0.2	0.5	-0.3	0.3	0.2
Baseline Anxiety	0.9	1.1	1.7	1.3	-1.3	1.3	1.3	-1.3	-0.1	-0.4	-0.6	-1.1	-0.8	-1.1
Tail length	0.5	1.8	4.5	1.1	-1.5	1.5	1.6	-1.6	-0.3	-0.2	-1.1	-2.1	-0.9	-1.4
Length with tail	0.3	1.2	2.2	-1.1	0.7	-0.7	-0.7	0.7	-1.5	-1.4	-1.4	-1.4	-1.2	-1.0
Length without tail	1.1	3.6	7.0	-2.6	2.6	-2.6	-2.6	2.6	-1.6	-1.4	-0.6	0.5	-0.5	0.6
Times rat made contact with spout	0.4	0.4	0.8	-0.8	0.9	-0.9	-0.9	0.9	-0.1	-0.4	0.3	0.4	0.3	0.4
Lifetime Intake	0.9	1.1	2.9	-0.7	1.0	-1.0	-1.2	1.2	0.3	-0.0	1.1	1.7	1.0	1.2
Liver weight, left	1.9	3.1	5.7	-1.3	1.2	-1.2	-1.3	1.3	-2.4	-2.4	-2.2	-1.1	-2.1	-2.2
Liver weight, right	2.6	4.5	7.1	-2.1	2.0	-2.0	-1.9	1.9	-2.7	-2.5	-2.5	-0.8	-2.3	-2.2
Locomotor activity	1.7	2.7	4.2	-2.1	1.7	-1.7	-1.8	1.8	-1.9	-1.7	-1.6	-1.0	-1.3	-0.8
Locomotor testing distance	0.0	0.1	0.1	0.3	-0.3	0.3	0.3	-0.3	0.4	0.3	0.0	-0.0	-0.0	0.0
Locomotor testing rearing	0.8	1.6	2.6	-1.6	1.6	-1.6	-1.6	1.6	-1.1	-1.1	-0.9	0.4	-0.9	-0.6
Locomotion in novel chamber	1.3	1.6	3.8	0.0	-0.3	0.3	0.3	-0.3	-1.5	-1.9	-1.6	-1.6	-1.6	-2.0
Locomotion in novel chamber post-restriction	0.4	0.6	1.5	1.2	-1.0	1.0	1.1	-1.1	0.4	0.5	0.0	-0.1	-0.3	-0.6
Fecal boli incidents, locomotor time 1	0.1	0.2	0.6	0.5	-0.4	0.4	0.5	-0.5	0.6	0.8	0.1	-0.2	0.1	0.0
Change in fecal boli incidents, locomotor task	1.4	1.4	3.8	-0.9	0.3	-0.3	-0.5	0.5	-1.9	-1.7	-1.2	-1.7	-1.5	-1.2
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	-0.2	0.3	-0.3	-0.4	0.4	-0.0	-0.5	-0.1	0.1	-0.2	0.1
Bouts of movement, locomotor time 1	0.1	0.2	0.4	-0.2	0.4	-0.4	-0.4	0.4	-0.0	0.5	0.6	0.6	0.1	0.0
Total resting periods, locomotor time 1	0.5	0.5	1.6	0.1	0.3	-0.3	-0.3	0.3	0.7	0.8	1.3	1.3	0.7	0.6
Rest time, locomotor task time 1	1.4	1.7	5.5	-0.4	1.0	-1.0	-0.9	0.9	1.1	1.2	1.8	2.4	1.3	1.3
Distance moved, locomotor task time 1	0.8	1.2	3.3	-0.9	0.7	-0.7	-0.7	0.7	-1.3	-1.8	-1.5	-0.8	-1.3	-0.8
Vertical activity count, locomotor time 1	0.1	0.3	1.3	-0.2	-0.2	0.2	0.1	-0.1	-0.5	-1.2	-0.7	-0.7	-0.4	-0.1
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.2	0.4	-0.4	0.4	0.4	-0.4	0.1	-0.1	-0.2	-0.2	-0.4	-0.4
Bouts of movement, locomotor time 2	0.5	0.8	3.1	-0.2	0.6	-0.6	-0.5	0.5	0.6	0.7	1.1	1.8	1.0	1.0
Total resting periods, locomotor time 2	0.5	0.9	3.2	-0.1	0.6	-0.6	-0.4	0.4	0.8	1.0	1.3	1.8	1.1	1.2
Rest time, locomotor task time 2	0.4	0.5	1.6	0.4	-0.1	0.1	0.1	-0.1	1.0	1.3	1.1	0.6	0.7	0.6
Distance moved, locomotor task time 2	1.0	1.2	2.5	-1.1	1.1	-1.1	-1.1	1.1	-1.3	-1.6	-1.1	-0.1	-1.0	-0.8
Vertical activity count, locomotor time 2	0.4	0.5	1.4	-0.6	0.4	-0.4	-0.3	0.3	-0.9	-1.2	-1.0	-0.5	-0.7	-0.6
Light reinforcement 1	0.5	1.1	2.8	-0.5	0.4	-0.4	-0.4	0.4	-1.2	-1.1	-1.6	-1.5	-1.7	-1.1
Light reinforcement 2	0.5	0.8	1.4	-0.9	1.2	-1.2	-1.0	1.0	-0.9	-0.8	-0.6	0.6	-0.9	-0.3
Bone: marrow area	1.9	4.2	8.5	-1.7	1.2	-1.2	-1.1	1.1	-2.4	-2.3	-2.9	-2.6	-2.8	-1.9
Bone: maximum diameter	3.1	5.9	9.8	-3.1	2.8	-2.8	-3.0	3.0	-2.6	-2.5	-2.0	-0.8	-1.7	-0.7
Bone: maximum force	1.3	2.3	5.0	-2.1	2.1	-2.1	-2.2	2.2	-0.7	-0.8	-0.3	0.7	0.1	0.8
Bone: maximum moment	1.5	2.6	5.3	-2.3	2.2	-2.2	-2.3	2.3	-0.9	-1.0	-0.4	0.5	0.0	0.7
Mean time between licks in bursts	0.2	0.5	0.9	0.9	-0.9	0.9	0.8	-0.8	0.7	0.8	0.4	0.4	0.6	-0.0
Mean num. licks in bursts	0.8	1.3	2.6	-1.6	1.6	-1.6	-1.5	1.5	-0.9	-0.9	-0.3	0.5	-0.3	-0.0
Cd content in liver	0.9	1.0	1.6	-1.2	1.2	-1.2	-1.2	1.2	-1.0	-1.2	-0.5	-0.3	-0.4	-0.6
Co content in liver	0.3	0.4	1.5	-0.1	0.2	-0.2	-0.2	0.2	0.7	0.6	1.0	0.6	1.2	0.8
Cu content in liver	4.0	4.8	9.8	2.8	-3.1	3.1	3.0	-3.0	1.4	1.7	0.7	-0.8	0.6	0.4
Fe content in liver	0.6	0.7	1.6	-1.3	0.8	-0.8	-0.8	0.8	-1.0	-0.7	-1.0	-0.9	-0.9	-0.1
K content in liver	0.8	0.7	1.4	1.1	-1.1	1.1	1.2	-1.2	0.8	0.8	0.4	-0.3	0.0	0.3
Mg content in liver	1.1	1.2	1.7	1.2	-1.1	1.1	1.0	-1.0	1.3	1.3	1.1	0.7	0.8	1.1
Mn content in liver	0.2	0.2	0.8	-0.1	0.1	-0.1	-0.1	0.1	-0.5	-0.6	-0.6	-0.6	-0.9	-0.7
Na content in liver	1.4	1.5	2.9	1.6	-1.7	1.7	1.7	-1.7	0.9	1.1	0.4	-0.2	0.4	0.2
Rb content in liver	0.1	0.2	0.4	-0.4	0.3	-0.3	-0.5	0.5	0.3	0.2	0.5	-0.1	0.4	0.7
Se content in liver	0.4	0.5	0.8	0.7	-0.9	0.9	0.9	-0.9	-0.2	-0.2	-0.5	-0.9	-0.7	-0.6
Sr content in liver	1.9	1.7	2.6	1.6	-1.4	1.4	1.5	-1.5	1.3	1.3	1.2	0.7	1.4	0.3
Zn content in liver	0.2	0.2	0.7	0.1	-0.3	0.3	0.2	-0.2	-0.5	-0.5	-0.7	-0.9	-0.6	-0.5
Bone: minimum diameter	0.8	1.5	2.6	-1.1	0.8	-0.8	-1.1	1.1	-1.6	-1.5	-1.6	-1.1	-1.4	-1.0
Time in familiar zone, hab. session 1	0.3	0.3	0.7	-0.1	0.1	-0.1	-0.4	0.4	-0.5	-0.8	-0.6	-0.5	-0.8	-0.7
Time in novel zone, hab. session 1	0.4	0.4	1.1	-1.0	0.8	-0.8	-0.5	0.5	-0.7	-0.4	-0.7	-0.5	-0.1	-0.4
Total zone transitions, hab. session 1	2.3	3.2	6.5	2.2	-2.4	2.4	2.6	-2.6	0.6	0.5	-0.1	-1.8	-0.7	-0.9
Total locomotion distance, hab. session 1	2.1	2.9	7.4	1.3	-1.7	1.7	1.8	-1.8	-0.6	-0.7	-1.5	-2.7	-2.0	-2.0
Locomotion velocity, hab. session 1	1.7	2.4	4.9	1.6	-1.8	1.8	1.9	-1.9	-0.1	-0.2	-1.0	-2.2	-1.5	-1.5
Time in familiar zone, hab. session 2	0.7	0.7	2.4	-0.1	0.0	-0.0	-0.1	0.1	-0.9	-1.1	-1.2	-0.6	-1.2	-1.6
Time in novel zone, hab. session 2	0.3	0.3	1.1	-0.3	0.2	-0.2	-0.2	0.2	0.4	0.6	0.6	-0.1	0.8	1.0
Total zone transitions, hab. session 2	0.5	0.6	1.3	0.9	-0.9	0.9	1.1	-1.1	0.6	0.6	0.4	-0.7	-0.1	0.3
Total locomotion distance, hab. session 2	0.4	0.5	1.0	0.9	-0.9	0.9	1.0	-1.0	0.6	0.6	0.3	-0.4	0.1	0.1
Locomotion velocity, hab. session 2	0.7	1.0	2.0	1.3	-1.3	1.3	1.4	-1.4	0.9	0.8	0.4	-0.5	0.1	0.1
Novel to familiar place preference ratio	2.4	2.6	4.1	-1.9	1.4	-1.4	-1.5	1.5	-2.0	-1.9	-1.8	-1.6	-1.2	-1.2
Novelty place preference	3.3	3.5	5.3	-2.2	1.6	-1.6	-1.8	1.8	-2.3	-2.2	-2.0	-1.7	-1.4	-1.5
Time in novel zone, NPP test	4.0	4.3	6.3	-2.5	1.9	-1.9	-2.1	2.1	-2.5	-2.4	-2.2	-1.8	-1.5	-1.5
Total zone transitions, NPP test	1.8	2.6	5.5	2.0	-2.2	2.2	2.3	-2.3	0.4	0.4	-0.1	-1.9	-0.5	-0.7
Total locomotion distance, NPP test	0.9	1.3	2.8	1.4	-1.5	1.5	1.7	-1.7	0.5	0.5	0.1	-1.2	-0.2	-0.3
Locomotion velocity, NPP test	1.4	2.0	4.2	1.9	-1.9	1.9	2.0	-2.0	0.8	0.7	0.2	-1.0	-0.2	-0.4
Intraocular pressure	0.3	0.4	1.1	-0.5	0.5	-0.5	-0.7	0.7	-0.7	-1.0	-0.6	-0.2	-0.5	-0.5
Delta distance traveled before/after self-admin	2.1	2.2	6.2	-1.2	0.7	-0.7	-0.8	0.8	-2.0	-2.5	-1.8	-1.9	-1.5	-1.1
Delta ambulatory time before/after self-admin	2.3	2.8	8.0	-1.4	0.8	-0.8	-0.9	0.9	-2.3	-2.8	-2.0	-2.2	-1.6	-1.1
Parametrial fat weight	0.2	0.4	1.5	0.1	0.1	-0.1	-0.1	0.1	-0.8	-0.6	-0.8	-0.0	-0.9	-1.2
Pavlov. Cond. lever latency	0.7	0.8	1.8	-1.0	0.6	-0.6	-0.8	0.8	-1.4	-1.3	-1.0	-0.9	-0.6	-0.8
Pavlov. Cond. magazine entry latency	1.2	1.5	3.2	1.2	-0.6	0.6	0.7	-0.7	1.8	1.6	1.6	1.5	1.3	1.1
Pavlov. Cond. change in total contacts	1.8	1.9	3.9	1.2	-0.8	0.8	0.8	-0.8	2.0	1.8	1.9	1.4	1.5	1.5
Pavlov. Cond. index score	1.3	1.6	3.4	0.9	-0.3	0.3	0.5	-0.5	1.8	1.7	1.7	1.8	1.4	1.4
Pavlov. Cond. latency score	1.1	1.4	3.1	0.8	-0.3	0.3	0.5	-0.5	1.8	1.6	1.6	1.6	1.3	1.3
Pavlov. Cond. lever contacts	1.9	2.2	4.2	1.7	-1.2	1.2	1.4	-1.4	2.0	2.0	1.6	1.3	1.2	1.1
Pavlov. Cond. magazine entry number	1.5	1.9	3.9	-1.2	0.6	-0.6	-0.7	0.7	-2.0	-1.8	-1.9	-1.8	-1.6	-1.3
Pavlov. Cond. intertrial magazine entries	0.7	0.9	1.5	1.0	-1.2	1.2	1.1	-1.1	0.9	0.9	0.7	-0.4	0.7	0.7
Pavlov. Cond. lever-magazine prob. diff.	1.3	1.6	3.4	1.1	-0.5	0.5	0.6	-0.6	1.9	1.7	1.7	1.7	1.3	1.3
Pavlov. Cond. response bias	1.7	2.1	4.1	1.4	-0.7	0.7	0.9	-0.9	2.0	1.9	1.9	1.9	1.5	1.4
Pavlov. Cond. lever latency	0.7	0.9	2.1	-0.8	0.9	-0.9	-0.9	0.9	-1.1	-1.3	-0.9	-0.2	-1.0	-1.4
Pavlov. Cond. magazine entry latency	4.4	5.3	7.0	2.2	-2.3	2.3	2.2	-2.2	2.6	2.6	2.5	0.9	2.4	2.6
Pavlov. Cond. change in total contacts	1.3	2.1	7.8	0.5	-0.7	0.7	0.5	-0.5	1.6	1.7	1.9	1.0	1.9	2.8
Pavlov. Cond. index score	2.4	3.2	5.5	1.6	-1.7	1.7	1.5	-1.5	2.0	2.1	2.0	0.8	2.0	2.4
Pavlov. Cond. latency score	3.0	4.0	6.1	1.8	-1.9	1.9	1.8	-1.8	2.3	2.3	2.2	0.7	2.1	2.5
Pavlov. Cond. lever contacts	0.8	1.1	2.0	1.0	-1.1	1.1	1.0	-1.0	1.1	1.3	0.8	0.0	0.9	1.4
Pavlov. Cond. magazine entry number	2.8	3.5	5.5	-1.7	1.9	-1.9	-1.7	1.7	-2.1	-2.0	-2.1	-0.6	-1.9	-2.3
Pavlov. Cond. intertrial magazine entries	1.8	2.7	5.7	-1.9	2.4	-2.3	-2.4	2.4	-0.5	-0.4	0.3	1.6	0.6	0.4
Pavlov. Cond. lever-magazine prob. diff.	2.4	3.2	5.1	1.7	-1.8	1.8	1.6	-1.6	2.0	2.1	1.9	0.6	1.8	2.3
Pavlov. Cond. response bias	1.2	1.7	3.6	1.1	-1.2	1.2	1.1	-1.1	1.3	1.5	1.3	0.4	1.4	1.9
Time in closed arm before self-admin	3.0	3.8	8.1	2.6	-2.8	2.8	2.8	-2.8	1.6	0.9	0.2	-0.5	0.6	-0.1
Time in closed arm after self-admin	0.1	0.1	0.6	0.2	0.1	-0.1	0.1	-0.1	0.4	-0.3	-0.2	0.8	-0.3	-0.5
Time in open arm before self-admin	0.0	0.0	0.2	0.1	-0.0	0.0	-0.1	0.1	-0.2	0.1	0.0	-0.2	-0.4	-0.4
Time in open arm after self-admin	0.9	1.0	3.3	0.2	-0.6	0.6	0.4	-0.4	-1.3	-0.8	-1.1	-1.8	-1.1	-1.2
Bone: periosteal estimation	1.9	3.9	6.2	-2.1	1.7	-1.7	-1.8	1.8	-2.4	-2.2	-2.5	-1.8	-2.2	-1.4
Bone: periosteal perimeter	4.1	7.1	10.2	-2.9	2.5	-2.5	-2.8	2.8	-3.2	-3.1	-2.9	-1.4	-2.6	-1.9
Bone: post-yield work	0.3	0.4	0.7	-0.5	0.7	-0.7	-0.8	0.8	0.3	0.2	0.5	0.6	0.7	0.8
Progressive ratio test 1 active lever presses	0.6	0.7	1.8	-0.2	0.4	-0.4	-0.5	0.5	0.8	0.6	1.2	1.3	1.0	1.2
Progressive ratio test 1 breakpoint	0.4	0.5	1.4	-0.1	0.3	-0.3	-0.4	0.4	0.8	0.5	1.1	1.2	0.9	1.1
Progressive ratio test 1 inactive lever presses	2.7	3.9	10.5	-0.5	1.1	-1.1	-1.1	1.1	1.9	1.2	2.8	3.2	2.7	2.8
Progressive ratio test 2 active lever presses	0.5	0.6	1.6	-0.1	0.3	-0.3	-0.6	0.6	0.7	0.1	1.3	1.1	1.1	1.3
Progressive ratio test 2 breakpoint	0.5	0.5	1.4	-0.0	0.2	-0.2	-0.5	0.5	0.7	0.1	1.2	1.0	1.0	1.1
Progressive ratio test 2 inactive lever presses	1.0	1.6	4.0	0.8	-0.6	0.6	0.5	-0.5	1.6	1.2	2.0	1.5	1.8	1.7
Incentive Sensitization - Responses	0.1	0.2	0.5	0.2	-0.0	0.0	-0.2	0.2	0.4	-0.4	0.7	0.3	0.6	0.6
Incentive Sensitization - Breakpoint	0.2	0.2	0.6	0.1	0.1	-0.1	-0.4	0.4	0.4	-0.3	0.8	0.5	0.7	0.8
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	-0.2	-0.0	0.0	-0.0	0.0	0.2	-0.1	-0.2	-0.3	-0.1	-0.2
Progressive ratio	0.3	0.4	0.9	0.3	-0.4	0.4	0.4	-0.4	0.9	0.9	0.7	0.5	0.8	0.7
Food seeking constrained by brief footshock	0.9	1.1	2.2	-1.4	1.4	-1.4	-1.5	1.5	-1.0	-0.6	-0.2	0.4	-0.3	0.2
Seeking ratio, punishment vs. effort	0.4	0.6	1.3	-0.9	1.1	-1.1	-1.1	1.1	-0.8	-0.5	-0.2	0.4	-0.4	-0.0
Retroperitoneal fat weight	2.5	10.8	20.3	-4.3	4.5	-4.5	-4.4	4.4	-2.8	-2.7	-1.6	1.0	-1.3	-0.3
Reaction time number correct	0.8	1.5	2.5	1.3	-1.6	1.6	1.4	-1.4	-0.5	-0.5	-0.7	-1.5	-1.2	-1.4
Reaction time mean minus median	0.1	0.3	0.7	-0.6	0.7	-0.7	-0.4	0.4	-0.6	-0.3	-0.8	-0.3	-0.3	-0.8
Reaction time mean minus median AUC	0.3	0.7	1.5	-1.0	1.2	-1.2	-1.0	1.0	-0.8	-0.6	-0.6	0.3	-0.2	-0.7
Reaction time num false alarms	0.6	0.9	2.2	-0.2	0.1	-0.1	-0.0	0.0	-1.0	-0.9	-1.5	-1.3	-1.4	-1.5
Reaction time num false alarms AUC	0.7	1.1	2.6	-0.1	-0.0	0.0	0.1	-0.1	-1.0	-1.0	-1.5	-1.6	-1.5	-1.6
Reaction time trials correct on left	0.8	1.5	2.5	1.3	-1.6	1.6	1.4	-1.4	-0.5	-0.5	-0.7	-1.5	-1.2	-1.4
Reaction time trials on left	0.9	1.7	2.6	1.3	-1.6	1.6	1.4	-1.4	-0.5	-0.5	-0.7	-1.6	-1.2	-1.4
Reaction time mean	0.1	0.1	0.4	0.3	-0.3	0.3	0.4	-0.4	0.3	0.6	0.4	0.1	0.6	0.2
Reaction time mean AUC	0.1	0.1	0.3	0.3	-0.2	0.2	0.4	-0.4	0.4	0.5	0.4	0.2	0.5	0.2
Median of all reaction times	0.3	0.4	0.6	0.7	-0.7	0.7	0.7	-0.7	0.6	0.8	0.6	0.1	0.7	0.4
Reaction time omissions	0.3	0.4	1.1	0.3	-0.4	0.4	0.6	-0.6	-0.5	-0.5	-0.5	-1.0	-0.6	-1.1
Reaction time false alarm rate	0.3	0.4	0.6	-0.7	0.8	-0.8	-0.6	0.6	-0.5	-0.4	-0.8	-0.3	-0.4	-0.5
Reaction time premature initiation rate	0.5	0.6	2.5	0.3	-0.3	0.3	0.3	-0.3	1.2	1.1	0.9	0.3	0.8	1.6
Reaction time premature initiations	0.3	0.5	0.8	0.7	-0.8	0.8	0.7	-0.7	0.8	0.7	0.6	-0.2	0.3	0.9
Std. dev. reaction times	0.3	0.5	0.9	-0.9	0.9	-0.9	-0.6	0.6	-0.8	-0.6	-0.7	-0.3	-0.3	-0.6
Reaction time trials completed	0.9	1.7	2.6	1.3	-1.6	1.6	1.4	-1.4	-0.5	-0.5	-0.7	-1.6	-1.2	-1.4
Reaction time trials AUC	0.7	1.4	2.3	1.1	-1.5	1.5	1.3	-1.3	-0.6	-0.6	-0.7	-1.5	-1.2	-1.3
Run reversals in cocaine runway, females	0.6	0.6	1.9	0.6	-0.5	0.5	0.7	-0.7	-0.5	-0.4	-0.9	-0.9	-1.4	-1.1
Run reversals in cocaine runway, males	1.7	1.8	3.5	-1.1	0.8	-0.8	-1.0	1.0	-1.9	-1.7	-1.4	-1.7	-1.5	-1.2
Latency to leave start box in cocaine runway	0.1	0.1	0.4	-0.2	0.3	-0.3	-0.3	0.3	0.2	0.6	0.2	0.6	0.2	0.2
Latency to leave start box in cocaine runway, F	0.2	0.2	0.8	0.4	-0.5	0.5	0.5	-0.5	0.3	0.9	-0.1	-0.2	-0.1	-0.2
Latency to leave start box in cocaine runway, M	0.6	0.6	1.1	-0.9	1.0	-1.0	-1.0	1.0	-0.2	-0.2	0.3	1.0	0.5	0.4
Std. dev. time between licks in bursts	1.1	1.5	2.0	1.2	-1.4	1.4	1.3	-1.3	1.4	1.4	0.9	-0.1	0.9	1.1
Total sessions with >9 infusions	3.7	4.5	8.1	-2.3	2.8	-2.8	-2.9	2.9	0.2	-0.1	1.1	2.4	1.2	1.9
Short access day 1 total inactive lever presses	1.2	1.6	3.1	-1.5	1.5	-1.5	-1.5	1.5	0.3	0.2	0.8	1.0	1.1	1.8
Short access day 10 total inactive lever presses	0.3	0.7	1.5	-1.2	1.1	-1.1	-1.0	1.0	-1.0	-0.3	-0.3	0.2	-0.3	-0.1
Short access day 1 total infusions	1.6	2.2	3.9	-1.7	2.0	-2.0	-2.0	2.0	0.1	0.1	0.7	1.5	0.9	1.5
Short access day 10 total infusions	1.2	1.6	4.1	-1.0	1.4	-1.4	-1.6	1.6	0.5	0.3	0.9	2.0	0.9	1.2
Short access total infusions	2.8	3.6	6.4	-1.7	2.2	-2.2	-2.3	2.3	0.6	0.6	1.5	2.5	1.6	2.1
Short access day 1 locomotion	0.8	1.0	2.9	-0.8	1.2	-1.2	-1.0	1.0	0.6	0.5	0.8	1.7	0.8	1.1
Short access day 10 total locomotion	0.9	1.7	5.5	0.3	0.2	-0.2	-0.3	0.3	1.9	1.7	1.6	2.4	1.5	1.3
Short access total locomotion	1.7	2.0	6.3	-0.9	1.4	-1.4	-1.4	1.4	1.1	1.1	1.3	2.5	1.3	1.5
One hour access (0.3 mA shock)	0.3	0.4	1.5	0.6	-0.3	0.3	0.2	-0.2	0.5	0.3	0.9	1.2	0.8	0.6
Compulsive drug intake	0.2	0.2	0.5	0.3	-0.4	0.4	0.4	-0.4	0.4	0.0	0.6	-0.7	0.5	0.4
One hour access (shock baseline)	0.2	0.3	2.1	0.4	-0.2	0.2	0.1	-0.1	0.2	-0.1	0.5	1.5	0.4	0.2
Social response proportion	0.3	0.4	1.1	-0.4	0.2	-0.2	-0.2	0.2	0.5	0.7	0.5	0.9	1.1	0.9
Social responses	0.3	0.4	1.3	0.0	-0.3	0.3	0.1	-0.1	-0.3	-0.4	-0.9	-1.1	-0.9	-0.7
Social time	1.2	1.6	2.8	1.7	-1.4	1.4	1.4	-1.4	1.5	1.5	1.2	0.6	0.9	0.6
Soleus weight	0.1	0.2	0.5	0.3	-0.2	0.2	0.5	-0.5	0.7	0.5	0.6	-0.0	0.6	0.7
Bone: stiffness	0.8	1.3	2.8	-1.5	1.6	-1.6	-1.7	1.7	-0.5	-0.3	-0.2	0.9	0.2	0.6
Tibialis anterior weight	0.7	2.4	3.7	1.7	-1.6	1.6	1.5	-1.5	1.9	1.8	1.4	0.5	1.8	0.9
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.8	-0.4	0.3	-0.3	-0.2	0.2	-0.3	0.2	-0.5	-0.9	-0.4	-0.2
Time to tail flick, vehicle, after self-admin	1.4	1.8	5.7	0.7	-1.2	1.2	1.2	-1.2	-0.9	-0.8	-1.5	-2.4	-1.5	-1.7
Time to tail flick, test, before self-admin	0.7	0.8	1.6	-0.7	1.0	-1.0	-0.9	0.9	-1.1	-1.3	-0.7	0.1	-0.9	-0.7
Time to tail flick, test, after self-admin	0.2	0.2	0.4	0.5	-0.5	0.5	0.5	-0.5	-0.2	-0.6	-0.4	-0.0	-0.5	-0.6
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.2	-0.1	-0.1	0.1	0.1	-0.1	-0.2	-0.4	-0.1	-0.3	0.1	0.0
Delta time to tail flick, test, before/after SA	1.4	1.4	2.9	1.5	-1.7	1.7	1.7	-1.7	0.9	0.5	0.2	-0.5	0.4	0.1
Tibia length	0.6	1.5	2.6	-1.6	1.5	-1.5	-1.4	1.4	-1.3	-1.5	-0.9	-0.6	-0.7	-0.1
Ambulatory time before self-admin	0.6	0.9	2.0	0.5	-0.1	0.1	0.2	-0.2	1.4	1.2	1.3	1.4	1.3	1.2
Ambulatory time after self-admin	0.4	0.4	0.9	0.7	-0.9	0.9	0.8	-0.8	0.3	-0.4	-0.1	-0.9	0.2	0.3
Bone: tissue strength	0.3	0.3	0.9	-0.5	0.2	-0.2	-0.4	0.4	-0.7	-0.8	-0.7	-1.0	-0.6	-0.2
Total heroin consumption	0.3	0.3	0.5	-0.5	0.7	-0.7	-0.6	0.6	0.6	0.2	0.5	0.3	0.5	0.6
Bone: trabecular number	0.1	0.2	0.5	0.3	-0.3	0.3	0.2	-0.2	-0.5	-0.5	-0.6	-0.2	-0.7	-0.6
Bone: trabecular spacing	0.7	0.9	2.0	-1.3	1.4	-1.4	-1.2	1.2	-0.4	-0.5	0.3	0.8	0.3	0.5
Bone: trabecular thickness	0.2	0.2	0.5	0.6	-0.5	0.5	0.3	-0.3	0.4	0.7	0.2	0.4	0.3	0.4
Bone: trabecular tissue density	1.9	2.8	5.4	1.7	-1.7	1.7	1.8	-1.8	2.1	2.3	1.4	0.1	1.5	1.1
Water consumed over 24 hours	0.3	0.4	0.8	-0.9	0.8	-0.8	-0.8	0.8	-0.5	-0.6	-0.2	-0.4	0.1	0.2
Number of responses in last shaping day	4.1	4.5	9.1	1.0	-0.3	0.3	0.6	-0.6	3.0	2.6	2.9	3.0	2.7	2.6