Hub : Genes

Ccdc134

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr7_113646742_113648134 0.16 0.07 0.0e+00 0.19 0.19 0.18 0.19 2.4e-17 3.5e-17 6.2e-17 1.0e-17
2 Brain mRNA stability Ccdc134 0.03 0.02 5.6e-04 0.04 0.04 0.04 0.04 1.3e-04 2.1e-04 1.6e-04 2.1e-04
3 Brain intron excision ratio chr7_113642764_113643317 0.18 0.08 0.0e+00 0.17 0.18 0.18 0.17 1.0e-15 2.0e-16 1.8e-16 4.9e-16
4 Adipose mRNA stability Ccdc134 0.03 0.02 7.8e-04 0.01 0.02 0.01 0.01 7.3e-03 4.2e-03 9.1e-03 7.8e-03
5 Liver mRNA stability Ccdc134 0.04 0.03 9.2e-05 0.01 0.02 0.02 0.02 1.3e-02 1.1e-03 2.0e-03 3.3e-03
6 Liver gene expression Ccdc134 0.17 0.07 0.0e+00 0.13 0.13 0.14 0.14 1.1e-14 2.7e-14 1.1e-15 8.6e-16
7 Eye isoform ratio NM_001024355.1 0.23 0.15 8.6e-03 0.16 0.1 0.21 0.22 1.7e-03 1.4e-02 3.3e-04 2.3e-04
8 BLA gene expression Ccdc134 0.21 0.11 5.8e-05 0.02 0.06 0.05 0.03 3.2e-02 6.3e-04 1.2e-03 5.9e-03
9 Brain gene expression Ccdc134 0.16 0.07 2.0e-12 0.07 0.12 0.11 0.12 5.6e-07 6.7e-11 4.5e-10 6.8e-11
10 LHb gene expression Ccdc134 0.39 0.19 1.6e-03 0.03 0.03 0.03 0.06 5.8e-02 8.0e-02 6.3e-02 2.0e-02
11 Adipose gene expression Ccdc134 0.23 0.1 0.0e+00 0.14 0.15 0.15 0.16 2.8e-15 8.2e-17 1.3e-16 3.7e-17
12 PL gene expression Ccdc134 0.05 0.03 2.8e-04 0.04 0.03 0.03 0.03 1.7e-05 3.5e-04 2.8e-04 3.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.51.1-0.9-0.8-0.70.70.90.8-1.10.60.30.3-0.30.4
Area under the delay curve0.20.20.8-0.8-0.3-0.60.40.20.4-0.10.90.30.30.4-0.4
BMI with tail1.13.58.72.42.62.9-2.6-1.8-0.30.70.10.61.51.9-2.1
BMI without tail0.10.10.50.40.20.7-0.40.10.1-0.3-0.70.00.10.3-0.2
Body weight1.04.17.72.82.72.6-2.8-2.5-2.02.6-1.1-0.6-0.00.4-1.0
Weight adjusted by age1.21.32.90.0-0.0-0.70.2-0.5-1.71.6-1.3-1.4-1.7-1.41.1
Bone surface0.50.82.2-0.3-0.6-1.10.50.1-0.80.3-0.5-1.1-1.5-1.41.2
Bone volume0.10.20.6-0.2-0.2-0.40.20.0-0.40.1-0.3-0.7-0.7-0.80.7
Breakpoint value in progressive ratio session0.30.30.80.1-0.10.30.00.50.7-0.60.50.90.80.7-0.6
Number of licking bursts0.20.20.7-0.5-0.7-0.90.80.40.2-0.20.00.0-0.3-0.30.4
Context. condit. distance diff. score4.55.49.42.93.03.0-2.9-3.1-2.62.6-2.0-1.5-0.6-0.4-0.4
Locomotion velocity, session 11.41.53.70.3-0.1-1.00.2-0.7-1.51.1-1.1-1.6-1.9-1.61.5
Locomotion distance, session 11.41.85.0-1.5-1.7-2.22.01.10.3-0.9-0.1-0.7-1.2-1.11.5
Locomotion velocity, session 20.40.51.20.80.70.2-0.5-0.7-1.10.9-0.6-1.0-0.9-0.00.5
Locomotion distance, session 22.02.85.1-1.8-1.8-1.91.91.92.1-2.31.91.30.90.8-0.1
Locomotion velocity, session 31.01.12.80.40.6-0.0-0.2-0.8-1.41.0-1.1-1.7-1.5-1.11.3
Locomotion distance, session 31.01.12.1-1.3-1.2-1.41.40.4-0.1-0.5-0.6-0.9-1.2-1.11.5
Stereotopy head waving bouts, day 30.60.71.81.01.00.6-1.0-1.0-1.11.3-0.3-0.8-0.5-0.40.0
Stereotopy head waving duration, day 32.93.57.42.32.21.6-2.1-2.0-2.52.7-1.5-1.6-1.2-0.90.3
Locomotion velocity, session 70.10.20.70.00.40.1-0.2-0.5-0.60.4-0.3-0.8-0.40.10.2
Locomotion distance, session 70.70.92.6-0.9-0.2-0.30.30.41.1-0.81.60.81.31.4-1.1
Stereotopy head waving bouts, day 74.55.18.82.01.51.0-1.5-2.1-3.02.6-2.8-2.7-2.6-2.41.9
Stereotopy head waving duration, day 73.44.17.21.71.31.0-1.3-1.7-2.72.4-2.7-2.4-2.3-2.11.8
Locomotion velocity, session 81.72.15.52.41.81.8-1.8-2.0-1.41.4-1.1-0.5-0.4-0.0-0.2
Locomotion distance, session 80.60.91.61.21.31.2-1.1-1.3-1.20.8-1.0-0.9-0.4-0.30.1
Degree of sensitization distance2.62.66.11.41.71.9-1.9-0.80.30.61.31.32.12.2-2.5
Degree of sensitization stereotypy3.64.07.31.61.10.7-1.1-1.8-2.62.2-2.7-2.4-2.4-2.31.9
Conditioned locomotion0.70.81.40.70.90.8-0.7-1.0-1.20.9-1.2-1.2-0.6-0.90.4
Cocaine response after cond. corrected0.10.10.30.20.20.2-0.1-0.3-0.40.1-0.5-0.5-0.2-0.2-0.3
Cocaine response after cond. not corrected0.20.20.60.30.30.3-0.0-0.2-0.60.1-0.7-0.7-0.4-0.4-0.0
Cocaine response before conditioning0.00.00.1-0.10.0-0.10.20.4-0.2-0.0-0.1-0.1-0.1-0.00.2
Saline control response1.31.64.10.40.3-0.1-0.1-0.6-1.81.3-1.6-1.6-1.7-2.01.5
Bone: connectivity density0.10.20.4-0.6-0.6-0.60.40.60.5-0.60.50.30.2-0.30.4
Bone: cortical apparent density0.40.61.1-1.1-0.9-1.10.90.80.9-0.80.80.40.2-0.20.1
Bone: cortical area1.01.63.51.91.81.6-1.7-1.5-1.31.3-0.8-0.5-0.20.2-0.4
Bone: cortical porosity0.40.51.00.80.91.0-0.8-0.5-0.80.6-0.7-0.5-0.2-0.50.2
Bone: cortical porosity0.91.01.81.31.31.3-1.2-0.9-1.11.0-0.9-0.7-0.3-0.50.1
Bone: cortical thickness0.81.43.10.70.71.1-0.8-0.21.0-0.51.11.61.81.7-1.7
Bone: cortical thickness1.11.33.00.80.71.1-0.8-0.50.7-0.20.81.51.61.7-1.7
Bone: cortical tissue density0.40.61.1-1.0-0.8-1.00.90.70.9-0.80.90.40.2-0.10.0
Condit. Reinf. active minus inactive responses0.40.51.8-0.5-0.1-0.40.30.50.6-0.51.30.60.71.0-0.8
Condit. Reinf. active-inactive response ratio0.20.20.50.50.70.2-0.5-0.6-0.60.70.1-0.3-0.20.20.0
Condit. Reinf. active responses1.11.32.7-1.4-0.9-1.11.21.51.2-1.21.61.00.81.0-0.7
Condit. Reinf. inactive responses1.72.14.4-2.0-1.6-1.51.82.11.5-1.61.31.10.70.5-0.3
Incentive salience index mean0.91.13.3-0.9-0.4-0.70.60.91.0-0.81.81.01.01.4-1.0
Condit. Reinf. lever presses0.70.92.4-1.2-0.7-1.00.91.20.9-0.81.50.60.61.1-0.7
Condit. Reinf. active minus inactive responses0.40.51.50.20.00.0-0.2-0.10.9-0.61.21.01.10.9-0.9
Condit. Reinf. active-inactive response ratio0.80.92.30.30.10.0-0.40.01.0-0.51.51.31.31.1-1.3
Condit. Reinf. active responses0.30.41.11.10.80.5-0.8-1.0-0.40.70.20.00.20.3-0.5
Condit. Reinf. inactive responses1.01.23.11.21.30.8-1.0-1.5-1.61.8-0.7-1.0-0.7-0.10.1
Condit. Reinf. lever presses0.30.41.0-0.4-0.6-0.50.50.60.7-0.61.00.70.50.2-0.2
Condit. Reinf. lever reinforcers received0.10.20.50.70.50.3-0.6-0.6-0.10.30.60.20.40.3-0.5
Conditioned reinforcement - actives0.50.51.70.60.80.4-0.5-1.1-1.01.3-0.4-0.6-0.2-0.1-0.0
Conditioned reinforcement - inactives0.40.41.20.00.2-0.0-0.10.20.50.01.01.10.61.0-0.9
Conditioned locomotion1.31.52.91.51.71.6-1.7-1.7-0.81.20.0-0.00.71.0-1.1
Patch foraging indifference point 0 sec0.30.51.1-0.5-0.7-0.50.61.11.0-0.90.91.00.3-0.00.0
Patch foraging indifference point AUC0.10.10.5-0.4-0.4-0.70.5-0.10.3-0.40.4-0.1-0.2-0.10.1
Delay disc. indifference point, 0s delay0.60.71.40.81.11.2-1.2-0.7-0.50.50.10.10.70.9-1.1
Delay disc. indifference point, 16s delay1.11.12.3-1.5-1.4-1.51.41.11.1-1.01.00.5-0.1-0.20.4
Delay disc. indifference point, 2s delay0.20.20.7-0.10.60.3-0.3-0.4-0.00.40.70.20.60.8-0.8
Delay disc. indifference point, 24s delay0.50.41.0-0.5-0.3-0.80.6-0.4-0.50.4-0.3-0.8-1.0-0.90.9
Delay disc. indifference point, 4s delay0.50.51.8-0.10.2-0.1-0.20.00.50.01.41.10.91.1-1.1
Delay disc. indifference point, 8s delay0.60.61.5-1.2-0.8-0.91.00.70.9-0.70.90.50.30.3-0.1
Indifference point function ln k0.60.81.81.21.21.3-1.3-0.9-0.91.0-0.7-0.4-0.1-0.0-0.1
Indifference point function log k0.60.81.81.21.21.3-1.3-0.9-0.91.0-0.7-0.4-0.1-0.0-0.1
Patch foraging total patch changes 0 sec0.40.61.4-0.7-0.9-0.60.71.21.0-0.90.91.00.3-0.10.1
Patch foraging total patch changes 12 sec0.10.10.80.10.1-0.2-0.00.10.3-0.10.90.40.30.1-0.2
Patch foraging total patch changes 18 sec0.30.41.2-0.2-0.4-0.30.20.50.9-0.61.11.00.70.4-0.5
Patch foraging total patch changes 24 sec0.20.20.5-0.5-0.6-0.70.60.50.4-0.40.40.2-0.1-0.20.2
Patch foraging total patch changes 6 sec0.10.20.7-0.0-0.3-0.40.40.50.5-0.40.70.80.10.2-0.3
Patch foraging time to switch 0 sec0.10.10.3-0.5-0.2-0.30.20.6-0.30.20.1-0.4-0.1-0.50.4
Patch foraging water rate 0 sec0.20.41.20.3-0.30.30.20.31.0-1.10.11.10.40.5-0.4
Patch foraging water rate 12 sec0.20.30.7-0.4-0.8-0.60.70.60.6-0.8-0.30.0-0.4-0.40.6
Patch foraging water rate 18 sec0.71.01.9-0.8-1.3-1.31.41.20.9-1.30.10.1-0.6-0.70.9
Patch foraging water rate 24 sec0.10.20.40.7-0.00.1-0.30.00.6-0.60.10.50.30.4-0.4
Patch foraging water rate 6 sec0.91.33.1-1.1-1.4-1.81.20.7-0.4-0.0-0.5-0.9-1.5-1.41.5
Seeking ratio, delayed vs. immediate footshock3.13.57.8-2.2-2.0-1.62.02.42.7-2.81.81.30.90.30.2
Distance traveled before self-admin1.61.84.7-0.20.30.6-0.20.51.5-0.81.91.82.21.8-1.7
Distance traveled after self-admin0.30.31.00.50.40.4-0.4-0.00.20.30.71.00.90.7-0.7
Extensor digitorum longus weight0.10.41.0-0.5-1.0-0.70.70.90.2-0.5-0.50.1-0.4-0.70.7
Bone: elastic displacement1.11.23.10.60.0-0.3-0.1-0.6-1.41.3-1.6-1.3-1.8-1.21.3
Bone: elastic work1.51.94.42.11.61.6-1.8-1.5-1.61.8-1.2-0.6-0.50.1-0.1
Bone: endosteal estimation2.24.79.61.61.30.6-1.1-1.7-3.12.5-2.7-3.0-2.8-2.31.9
Bone: endosteal perimeter3.06.312.71.91.91.2-1.7-2.3-3.63.0-3.1-3.3-2.8-2.21.7
Epididymis fat weight2.35.29.22.62.92.6-2.7-3.0-2.82.9-1.9-2.0-0.8-0.1-0.4
Delta time in closed arm before/after self-admin1.31.32.51.01.61.4-1.3-1.3-0.40.90.60.21.21.2-1.4
Delta time in open arm before/after self-admin0.60.51.3-0.3-0.6-0.50.60.5-0.40.2-1.0-0.7-1.0-1.11.2
Diff in mean of infusions in LGA sessions0.40.40.9-0.7-0.6-0.60.70.60.7-0.41.00.70.80.5-0.3
Delay discount exponential model param0.20.20.70.80.40.7-0.5-0.2-0.30.0-0.8-0.3-0.2-0.30.2
Extinction: sum of active levers before priming0.10.10.30.20.10.1-0.00.00.10.20.30.40.60.5-0.4
Active lever presses in extinction session 60.30.30.80.50.40.5-0.5-0.2-0.20.40.20.40.90.6-0.6
Bone: final force1.01.63.11.71.81.8-1.7-1.2-0.10.50.70.91.21.2-1.4
Bone: final moment1.11.73.61.91.81.8-1.8-1.4-0.30.70.50.71.01.1-1.3
Food consumed during 24 hour testing period1.11.32.71.61.61.4-1.5-1.2-0.61.20.10.40.60.9-1.4
Glucose0.30.41.3-0.8-0.7-0.50.61.10.6-0.60.80.60.40.3-0.3
Heart weight2.23.17.72.42.22.8-2.3-1.4-0.61.4-0.31.11.31.4-1.9
Delay discount hyperbolic model param0.20.20.70.60.10.5-0.3-0.0-0.2-0.1-0.8-0.3-0.3-0.50.4
Intermittent access intake day 1-15 change0.30.30.9-0.7-0.9-0.90.60.50.5-0.30.50.4-0.20.10.2
Intermittent access intake escalation0.40.31.0-0.7-1.0-0.90.60.60.5-0.30.50.5-0.2-0.00.2
Intermittent access intake escalation 20.20.20.5-0.4-0.7-0.70.40.4-0.10.2-0.1-0.0-0.6-0.30.4
Intermitt. access day 1 inactive lever presses0.80.92.00.80.61.0-0.8-0.10.7-0.30.81.31.11.4-1.3
Intermitt. access day 15 inactive lever presses2.52.76.41.01.01.4-1.1-0.61.5-0.91.72.02.52.3-2.3
Intermitt. access escalation Index0.30.20.6-0.1-0.20.0-0.00.20.8-0.60.60.80.60.5-0.4
Intermittent access day 1 total infusions0.70.81.91.11.41.1-1.2-1.1-0.40.90.20.30.60.9-0.9
Intermittent access day 15 total infusions0.20.20.70.00.0-0.1-0.1-0.00.5-0.00.70.80.40.6-0.6
Intermittent access terminal intake (last 3 days)0.00.10.20.10.30.0-0.2-0.3-0.20.50.10.0-0.10.2-0.2
Intermittent access total infusions0.20.30.50.50.70.6-0.6-0.50.00.40.40.40.40.6-0.7
Intermittent access day 1 locomotion0.40.40.80.60.90.8-0.8-0.5-0.10.50.40.50.80.9-0.7
Intermittent access day 15 total locomotion0.10.10.30.20.30.3-0.4-0.3-0.20.50.20.10.10.1-0.2
Intermittent access total locomotion0.40.50.80.60.80.8-0.8-0.50.00.50.60.60.90.9-0.9
Intermittent access standard deviation0.70.71.50.90.81.1-1.0-0.40.30.10.50.90.81.1-1.2
Left kidney weight7.922.249.07.06.65.9-6.4-6.3-4.35.1-2.2-1.60.01.1-2.2
Right kidney weight8.724.552.17.27.06.4-6.7-6.5-4.45.4-2.0-1.20.41.7-2.7
Cocaine induced anxiety1.21.44.11.10.91.3-1.1-0.30.7-0.20.81.42.01.6-1.6
Post-drug Anxiety0.40.41.40.70.30.6-0.6-0.10.5-0.30.30.81.20.7-0.6
Baseline Anxiety1.01.12.0-1.2-1.2-1.41.30.7-0.0-0.4-0.5-0.8-1.3-1.31.4
Tail length0.20.71.3-0.6-0.9-0.90.80.6-0.50.4-0.9-0.5-1.2-1.01.1
Length with tail0.41.64.91.10.80.2-0.9-1.2-1.92.2-1.1-1.2-1.3-1.10.7
Length without tail0.61.43.31.51.70.9-1.6-1.7-1.31.80.2-0.5-0.1-0.1-0.4
Times rat made contact with spout0.70.81.61.11.00.9-1.0-1.0-0.50.90.20.50.51.0-1.3
Lifetime Intake1.01.22.31.01.31.2-1.1-0.70.40.30.91.01.21.4-1.5
Liver weight, left1.52.45.60.71.00.4-0.9-1.3-2.42.4-1.5-2.0-1.8-1.61.2
Liver weight, right2.64.49.91.51.91.2-1.8-2.3-3.13.1-2.1-2.6-1.9-1.51.0
Locomotor activity1.32.14.42.11.81.6-1.8-1.8-1.61.6-1.5-1.2-0.6-0.5-0.0
Locomotor testing distance0.00.00.2-0.1-0.0-0.30.10.1-0.0-0.0-0.0-0.2-0.0-0.40.0
Locomotor testing rearing1.21.83.81.61.81.4-1.6-1.6-1.72.0-1.0-0.9-0.20.0-0.7
Locomotion in novel chamber1.92.45.1-0.6-0.8-1.00.80.1-1.61.2-2.3-2.0-2.2-2.11.9
Locomotion in novel chamber post-restriction0.60.71.9-1.4-1.0-1.01.21.10.5-0.80.3-0.2-0.3-0.50.7
Fecal boli incidents, locomotor time 10.30.30.8-0.6-0.7-0.60.70.60.7-0.90.50.20.30.00.1
Change in fecal boli incidents, locomotor task1.01.01.70.70.4-0.0-0.4-1.2-1.31.2-1.2-1.2-1.3-1.10.9
Time >=10cm from walls, locomotor time 10.00.00.10.10.30.2-0.2-0.10.0-0.20.3-0.20.1-0.0-0.0
Bouts of movement, locomotor time 10.10.20.40.00.40.3-0.3-0.40.3-0.30.40.00.70.6-0.6
Total resting periods, locomotor time 10.50.51.3-0.20.30.3-0.10.00.8-0.71.00.61.21.0-1.0
Rest time, locomotor task time 11.51.64.20.20.81.1-0.6-0.11.2-0.81.61.32.01.9-1.9
Distance moved, locomotor task time 11.11.23.80.70.70.3-0.7-0.9-1.81.9-1.1-1.1-1.3-0.70.5
Vertical activity count, locomotor time 10.20.20.80.1-0.2-0.4-0.1-0.0-0.70.9-0.3-0.2-0.8-0.50.5
Time >=10cm from walls, locomotor time 20.10.10.2-0.5-0.3-0.40.40.3-0.1-0.2-0.0-0.4-0.3-0.30.3
Bouts of movement, locomotor time 20.91.02.50.20.60.7-0.7-0.20.8-0.31.21.11.61.5-1.5
Total resting periods, locomotor time 21.01.12.70.10.40.6-0.6-0.11.0-0.51.31.21.71.6-1.6
Rest time, locomotor task time 20.20.30.6-0.3-0.1-0.20.30.30.8-0.80.70.60.60.4-0.3
Distance moved, locomotor task time 20.91.13.11.01.10.8-1.0-1.0-1.61.8-1.0-0.9-0.7-0.1-0.1
Vertical activity count, locomotor time 20.40.41.00.80.40.4-0.7-0.7-1.01.0-0.8-0.6-0.6-0.20.1
Light reinforcement 10.50.92.70.40.30.2-0.2-0.6-0.80.0-1.3-1.6-1.1-1.51.3
Light reinforcement 20.30.41.20.71.10.9-1.0-0.9-0.50.0-0.3-0.90.2-0.1-0.1
Bone: marrow area2.34.910.11.61.40.6-1.2-1.8-3.22.5-2.7-3.0-2.8-2.31.9
Bone: maximum diameter3.25.810.43.23.02.6-2.9-2.9-3.03.1-2.0-1.6-1.1-0.5-0.2
Bone: maximum force1.72.96.42.52.52.5-2.4-2.0-0.81.10.00.41.01.2-1.4
Bone: maximum moment1.93.27.42.72.62.6-2.6-2.1-0.91.2-0.10.30.81.2-1.4
Mean time between licks in bursts0.30.40.9-1.0-0.9-0.60.81.00.6-0.60.20.50.3-0.20.3
Mean num. licks in bursts1.11.32.61.41.51.4-1.6-1.4-1.11.5-0.3-0.10.10.6-0.9
Cd content in liver1.41.63.31.61.31.4-1.0-1.3-1.61.8-1.7-0.5-0.7-0.20.3
Co content in liver0.50.62.11.10.91.4-0.8-0.60.4-0.6-0.30.61.00.5-0.6
Cu content in liver2.63.27.0-2.7-2.5-2.62.32.41.3-1.51.20.50.0-0.60.7
Fe content in liver0.50.51.20.40.3-0.1-0.2-0.1-1.11.0-0.7-0.9-1.0-0.90.8
K content in liver0.70.71.9-0.7-0.8-0.90.60.90.9-0.91.40.80.70.7-0.7
Mg content in liver1.41.54.3-1.1-1.0-1.10.91.41.3-1.02.11.41.10.8-1.0
Mn content in liver0.30.30.90.40.60.3-0.3-0.8-0.80.7-0.5-1.0-0.6-0.50.3
Na content in liver2.02.14.0-2.0-2.0-1.61.82.01.6-2.00.90.70.4-0.20.2
Rb content in liver0.10.10.30.20.2-0.1-0.00.00.10.30.60.40.20.1-0.4
Se content in liver0.50.61.5-1.0-0.9-1.21.10.70.0-0.3-0.0-0.6-0.8-0.60.9
Sr content in liver0.50.40.9-0.9-0.9-0.41.00.80.8-0.9-0.10.50.20.40.1
Zn content in liver0.91.02.0-1.2-1.4-1.41.31.10.3-0.7-0.2-0.3-0.6-1.11.1
Bone: minimum diameter0.91.63.21.21.10.8-1.0-1.2-1.81.4-1.6-1.6-1.3-1.00.7
Time in familiar zone, hab. session 10.20.20.40.10.0-0.3-0.1-0.6-0.50.5-0.3-0.7-0.6-0.10.3
Time in novel zone, hab. session 10.70.72.11.20.81.4-0.9-0.5-0.60.3-1.4-0.2-0.2-0.50.2
Total zone transitions, hab. session 12.12.97.2-2.2-2.3-2.72.51.50.7-1.40.1-0.6-1.1-1.41.7
Total locomotion distance, hab. session 12.13.06.1-1.4-1.6-2.21.80.6-0.7-0.2-1.3-2.0-2.4-2.32.5
Locomotion velocity, hab. session 11.82.55.5-1.6-1.7-2.31.91.0-0.3-0.5-0.7-1.5-1.9-1.82.1
Time in familiar zone, hab. session 21.11.12.5-0.1-0.1-0.40.2-0.3-1.41.3-1.4-1.5-1.6-1.11.2
Time in novel zone, hab. session 20.50.51.20.60.20.6-0.4-0.10.8-0.70.61.11.00.7-0.8
Total zone transitions, hab. session 20.40.51.6-0.8-0.9-1.31.00.60.6-0.80.80.20.0-0.20.2
Total locomotion distance, hab. session 20.40.51.4-0.8-1.0-0.90.90.80.8-1.20.40.10.00.10.2
Locomotion velocity, hab. session 20.71.01.9-1.3-1.4-1.41.31.10.9-1.30.60.1-0.1-0.00.4
Novel to familiar place preference ratio2.52.64.81.91.41.5-1.6-1.9-1.91.9-2.2-1.1-1.2-1.40.5
Novelty place preference3.43.46.32.21.61.7-1.8-2.2-2.22.3-2.5-1.3-1.4-1.40.5
Time in novel zone, NPP test4.04.17.12.51.92.0-2.1-2.5-2.42.5-2.7-1.4-1.4-1.40.5
Total zone transitions, NPP test1.52.15.7-1.7-2.0-2.42.11.20.6-1.20.0-0.4-1.0-1.01.5
Total locomotion distance, NPP test0.71.02.3-1.2-1.4-1.51.51.00.7-1.30.2-0.1-0.4-0.30.8
Locomotion velocity, NPP test1.21.73.9-1.7-1.8-2.01.91.40.8-1.40.3-0.2-0.5-0.50.9
Intraocular pressure0.20.30.80.60.60.6-0.5-0.9-0.50.5-0.7-0.5-0.3-0.0-0.0
Delta distance traveled before/after self-admin1.61.73.81.00.50.0-0.6-1.2-2.01.8-1.7-1.4-1.5-1.41.1
Delta ambulatory time before/after self-admin1.82.04.71.20.5-0.1-0.7-1.3-2.22.0-1.8-1.4-1.6-1.41.2
Parametrial fat weight0.30.51.20.30.71.0-0.5-0.30.6-0.50.60.61.10.9-1.0
Pavlov. Cond. lever latency0.81.02.41.30.91.3-1.1-1.3-0.80.6-1.5-0.6-0.5-0.90.5
Pavlov. Cond. magazine entry latency1.41.73.5-1.2-0.7-0.70.91.21.6-1.41.91.41.41.5-1.4
Pavlov. Cond. change in total contacts1.92.04.5-1.1-0.7-0.80.91.31.6-1.22.11.61.51.9-1.5
Pavlov. Cond. index score1.31.64.3-0.8-0.2-0.40.50.91.4-0.92.11.51.51.9-1.6
Pavlov. Cond. latency score1.11.33.5-0.7-0.2-0.40.50.91.2-0.81.91.31.41.7-1.5
Pavlov. Cond. lever contacts1.41.73.5-1.4-0.9-1.11.11.51.4-1.21.91.11.11.4-1.0
Pavlov. Cond. magazine entry number1.11.33.01.00.50.6-0.7-0.9-1.20.8-1.7-1.3-1.2-1.71.4
Pavlov. Cond. intertrial magazine entries0.70.81.6-1.0-1.3-1.11.01.11.1-1.10.70.80.3-0.10.2
Pavlov. Cond. lever-magazine prob. diff.1.31.74.3-1.0-0.4-0.60.71.01.4-1.12.11.41.51.7-1.5
Pavlov. Cond. response bias1.62.05.0-1.3-0.6-0.70.91.21.6-1.32.21.41.61.8-1.6
Pavlov. Cond. lever latency0.60.72.00.81.21.1-1.0-1.4-0.80.7-1.0-0.7-0.00.0-0.1
Pavlov. Cond. magazine entry latency4.24.98.9-2.1-2.3-1.91.92.63.0-2.82.82.41.71.0-0.4
Pavlov. Cond. change in total contacts1.52.16.4-0.6-0.9-0.80.41.42.0-1.52.52.01.61.1-0.8
Pavlov. Cond. index score2.43.15.5-1.6-1.9-1.71.62.22.3-2.12.41.91.20.7-0.3
Pavlov. Cond. latency score3.13.96.9-1.8-2.1-1.81.72.42.6-2.42.62.11.40.9-0.4
Pavlov. Cond. lever contacts0.70.92.2-0.8-1.1-1.00.91.51.1-1.01.40.90.40.1-0.1
Pavlov. Cond. magazine entry number2.73.36.51.61.81.5-1.4-2.0-2.52.3-2.6-2.0-1.5-1.00.4
Pavlov. Cond. intertrial magazine entries2.43.27.52.32.52.7-2.1-1.9-0.61.2-0.20.71.31.8-2.0
Pavlov. Cond. lever-magazine prob. diff.2.43.15.2-1.7-2.0-1.81.62.32.2-2.12.31.71.10.5-0.1
Pavlov. Cond. response bias1.11.53.6-1.0-1.2-1.10.91.61.6-1.51.91.40.80.5-0.3
Time in closed arm before self-admin3.43.89.6-2.6-2.6-2.32.53.11.9-2.01.01.1-0.0-0.51.0
Time in closed arm after self-admin0.50.51.40.30.90.6-0.8-0.5-0.81.20.1-0.10.60.7-0.7
Time in open arm before self-admin0.30.31.1-0.10.1-0.10.1-0.5-0.80.5-0.6-1.1-0.8-0.60.5
Time in open arm after self-admin0.90.92.3-0.5-0.8-0.70.80.5-0.4-0.0-1.2-1.2-1.5-1.41.4
Bone: periosteal estimation2.04.18.02.21.91.4-1.8-2.1-2.82.5-2.3-2.2-2.0-1.41.0
Bone: periosteal perimeter3.55.710.02.72.62.1-2.4-2.7-3.22.9-2.6-2.5-1.8-1.30.7
Bone: post-yield work0.40.51.20.90.80.9-0.7-0.50.10.10.40.70.71.1-1.0
Progressive ratio test 1 active lever presses0.80.92.40.50.70.7-0.8-0.50.6-0.01.11.01.11.5-1.4
Progressive ratio test 1 breakpoint0.50.51.60.30.60.5-0.5-0.50.50.00.90.70.91.3-1.1
Progressive ratio test 1 inactive lever presses2.32.56.00.70.91.3-1.00.11.5-0.71.82.21.92.5-2.3
Progressive ratio test 2 active lever presses0.70.82.00.10.20.1-0.0-0.01.0-0.51.41.31.21.2-1.1
Progressive ratio test 2 breakpoint1.01.12.60.30.50.4-0.3-0.11.1-0.41.51.51.41.6-1.4
Progressive ratio test 2 inactive lever presses1.82.15.1-0.2-0.3-0.00.20.72.0-1.42.02.31.91.8-1.6
Incentive Sensitization - Responses0.50.51.70.0-0.1-0.10.30.40.9-0.41.21.30.71.0-0.8
Incentive Sensitization - Breakpoint0.60.61.90.20.10.10.10.20.9-0.41.31.40.91.2-1.0
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.20.00.10.40.2-0.10.10.30.20.2-0.1
Progressive ratio0.20.20.6-0.1-0.4-0.10.20.60.5-0.50.50.80.50.3-0.2
Food seeking constrained by brief footshock1.01.22.51.51.61.4-1.6-1.5-0.81.1-0.3-0.30.30.6-0.7
Seeking ratio, punishment vs. effort0.40.51.30.81.20.9-1.0-1.1-0.40.7-0.1-0.40.20.5-0.5
Retroperitoneal fat weight2.27.214.83.33.83.5-3.6-3.6-2.63.1-1.0-1.30.20.9-1.5
Reaction time number correct1.21.73.3-1.5-1.5-1.81.60.8-0.1-0.4-0.7-1.2-1.5-1.61.7
Reaction time mean minus median0.50.62.00.70.60.8-0.4-0.5-0.91.0-1.4-0.4-0.6-0.90.5
Reaction time mean minus median AUC0.70.92.11.11.11.3-0.9-0.8-1.11.5-1.2-0.3-0.3-0.4-0.1
Reaction time num false alarms0.71.02.70.10.0-0.10.1-0.2-1.00.3-1.6-1.5-1.4-1.61.3
Reaction time num false alarms AUC0.81.13.20.0-0.1-0.20.3-0.2-0.90.0-1.6-1.5-1.4-1.81.3
Reaction time trials correct on left1.21.73.3-1.5-1.5-1.81.60.8-0.1-0.4-0.7-1.2-1.5-1.61.7
Reaction time trials on left1.31.83.5-1.6-1.5-1.91.60.8-0.1-0.4-0.7-1.3-1.6-1.61.7
Reaction time mean0.10.10.3-0.2-0.2-0.00.30.60.4-0.4-0.10.40.1-0.30.2
Reaction time mean AUC0.00.10.3-0.2-0.2-0.10.30.50.3-0.2-0.10.30.1-0.10.1
Median of all reaction times0.20.30.8-0.6-0.5-0.40.60.90.9-0.80.40.60.40.00.1
Reaction time omissions0.20.30.7-0.4-0.7-0.40.70.30.0-0.4-0.8-0.3-0.4-0.60.7
Reaction time false alarm rate0.20.31.00.80.60.8-0.5-0.5-0.50.1-1.0-0.5-0.2-0.50.2
Reaction time premature initiation rate0.30.51.5-0.2-0.4-0.50.30.80.9-0.91.20.80.60.4-0.2
Reaction time premature initiations0.40.61.3-0.8-0.9-1.10.80.90.8-0.90.90.20.0-0.20.4
Std. dev. reaction times0.40.61.51.00.91.0-0.8-0.7-0.80.9-1.2-0.4-0.4-0.70.3
Reaction time trials completed1.31.83.5-1.6-1.5-1.91.60.8-0.1-0.4-0.7-1.3-1.6-1.61.7
Reaction time trials AUC1.11.63.0-1.4-1.3-1.71.40.7-0.2-0.2-0.6-1.3-1.5-1.51.6
Run reversals in cocaine runway, females1.51.42.8-1.2-0.9-1.41.00.4-0.70.1-0.7-1.6-1.6-1.71.7
Run reversals in cocaine runway, males1.11.11.81.00.70.3-0.5-1.3-1.31.2-1.3-1.2-1.2-0.90.9
Latency to leave start box in cocaine runway0.10.10.30.20.50.6-0.4-0.3-0.00.1-0.00.00.40.3-0.5
Latency to leave start box in cocaine runway, F0.20.20.5-0.7-0.6-0.50.60.60.4-0.60.1-0.1-0.1-0.20.3
Latency to leave start box in cocaine runway, M1.71.63.21.41.71.8-1.6-1.2-0.30.80.30.61.31.2-1.7
Std. dev. time between licks in bursts0.81.01.9-1.1-1.3-1.41.11.40.9-0.91.10.90.30.10.2
Total sessions with >9 infusions1.51.63.21.51.81.7-1.6-1.4-0.30.90.60.61.11.3-1.5
Short access day 1 total inactive lever presses1.01.12.31.51.41.5-1.5-1.2-0.10.40.10.50.90.9-1.0
Short access day 10 total inactive lever presses0.40.41.11.10.60.8-0.9-0.8-0.70.7-0.8-0.30.1-0.1-0.2
Short access day 1 total infusions1.81.93.71.71.81.9-1.8-1.3-0.00.60.50.81.31.5-1.7
Short access day 10 total infusions0.91.01.90.71.21.2-1.0-0.50.40.10.90.81.31.4-1.4
Short access total infusions2.83.25.91.72.12.3-2.0-1.30.40.41.21.42.12.3-2.4
Short access day 1 locomotion0.70.82.10.20.71.0-0.6-0.10.7-0.51.00.91.51.3-1.2
Short access day 10 total locomotion0.40.41.3-0.10.50.7-0.20.40.5-0.30.70.61.11.0-0.9
Short access total locomotion1.81.93.71.01.71.9-1.4-0.70.40.10.91.01.91.9-1.8
One hour access (0.3 mA shock)0.20.20.4-0.5-0.4-0.40.50.50.7-0.40.50.50.30.3-0.2
Compulsive drug intake1.11.22.7-1.1-1.5-1.61.61.01.0-1.20.10.3-0.4-0.70.9
One hour access (shock baseline)0.10.10.3-0.10.50.4-0.30.0-0.10.50.40.10.20.5-0.6
Social response proportion0.50.61.40.40.20.9-0.50.40.6-0.40.41.21.10.9-1.0
Social responses0.20.20.50.1-0.2-0.40.2-0.1-0.50.2-0.6-0.7-0.7-0.70.6
Social time1.11.52.9-1.5-1.3-1.31.51.71.4-1.31.30.90.60.5-0.3
Soleus weight0.10.30.7-0.3-0.5-0.40.40.30.8-0.80.80.70.60.6-0.3
Bone: stiffness1.11.74.21.81.92.0-1.8-1.3-0.40.60.20.51.01.1-1.3
Tibialis anterior weight0.72.46.2-1.3-1.6-0.81.31.72.3-2.51.21.81.60.6-0.7
Time to tail flick, vehicle, before self-admin0.40.41.10.30.0-0.10.0-0.4-0.70.2-0.9-0.9-1.0-0.70.8
Time to tail flick, vehicle, after self-admin2.32.45.0-0.9-1.2-1.61.30.5-1.20.5-1.8-1.8-2.1-2.22.2
Time to tail flick, test, before self-admin0.80.82.3-0.00.2-0.30.0-0.6-1.51.2-1.0-1.4-1.0-0.90.8
Time to tail flick, test, after self-admin0.80.82.1-1.5-1.3-1.31.21.10.2-0.40.2-0.2-0.6-0.70.9
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.3-0.5-0.30.30.60.4-0.20.20.40.3-0.00.0
Delta time to tail flick, test, before/after SA1.71.53.1-1.6-1.7-1.51.51.71.2-1.30.60.6-0.5-0.60.8
Tibia length0.61.64.01.71.51.0-1.5-1.7-1.52.0-0.5-0.5-0.5-0.6-0.2
Ambulatory time before self-admin1.11.22.2-0.10.20.5-0.10.31.5-1.11.51.51.41.5-1.3
Ambulatory time after self-admin0.10.10.5-0.2-0.5-0.70.40.40.00.20.20.40.1-0.30.4
Bone: tissue strength0.10.10.30.50.20.0-0.4-0.3-0.40.5-0.2-0.1-0.3-0.10.2
Total heroin consumption0.20.20.60.40.10.3-0.2-0.20.5-0.30.50.60.80.6-0.6
Bone: trabecular number0.20.20.9-0.4-0.2-0.30.1-0.1-0.2-0.1-0.4-0.8-0.5-0.90.8
Bone: trabecular spacing0.91.12.01.21.21.0-1.3-1.1-0.61.30.30.40.61.4-1.4
Bone: trabecular thickness0.30.31.9-0.5-0.4-0.10.40.70.8-1.40.2-0.00.4-0.30.5
Bone: trabecular tissue density1.21.64.5-1.0-1.2-0.61.21.81.9-2.10.91.40.90.2-0.2
Water consumed over 24 hours0.60.72.21.51.00.8-1.0-1.2-0.91.1-0.6-0.1-0.3-0.0-0.3
Number of responses in last shaping day1.92.03.9-0.8-0.6-0.20.51.32.0-1.62.02.01.61.5-1.3