Cbx7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Cbx7 0.4 0.13 7.5e-07 0.26 0.22 0.31 0.24 8.1e-07 4.5e-06 3.7e-08 1.7e-06
2 NAcc isoform ratio XM_063263925.1 0.04 0.02 5.3e-05 0.03 0.01 0.02 0.02 5.0e-05 1.8e-03 2.0e-04 4.2e-04
3 Adipose isoform ratio XM_039079590.2 0.05 0.03 7.1e-05 0.03 0.03 0.03 0.02 1.9e-04 2.2e-04 3.3e-04 1.4e-03
4 IL mRNA stability Cbx7 0.31 0.13 3.9e-04 0 0.1 0.08 0.06 2.4e-01 1.9e-03 5.2e-03 1.5e-02
5 pVTA isoform ratio XM_063263925.1 0.07 0.04 8.9e-04 0.04 0.04 0.04 0.04 1.5e-04 5.2e-04 1.5e-04 4.5e-04
6 Adipose isoform ratio XM_063263925.1 0.11 0.05 7.3e-09 0.06 0.05 0.06 0.04 1.9e-07 1.6e-06 4.0e-07 2.0e-05
7 Brain mRNA stability Cbx7 0.18 0.1 1.4e-07 0.04 0.06 0.07 0.08 7.0e-05 5.1e-06 2.7e-07 1.0e-07
8 IC mRNA stability Cbx7 0.56 0.13 2.7e-14 0.35 0.32 0.35 0.37 2.7e-15 6.6e-14 2.1e-15 3.0e-16
9 Brain isoform ratio XM_063263925.1 0.1 0.05 6.3e-07 0.05 0.08 0.06 0.06 3.2e-05 1.3e-07 1.2e-06 1.5e-06
10 Liver mRNA stability Cbx7 0.13 0.06 5.4e-12 0.11 0.1 0.09 0.1 5.2e-12 7.1e-11 2.4e-10 2.0e-11
11 PL mRNA stability Cbx7 0.33 0.1 0.0e+00 0.34 0.32 0.34 0.33 1.4e-37 6.9e-36 9.2e-38 3.3e-37
12 NAcc gene expression Cbx7 0.05 0.02 7.0e-08 0.06 0.05 0.05 0.05 1.9e-09 5.3e-08 1.3e-08 2.5e-08
13 Liver alternative TSS NM_199117.2 0.03 0.02 4.7e-03 0.03 0.01 0.02 0.02 3.2e-04 8.8e-03 1.3e-03 1.1e-03
14 pVTA mRNA stability Cbx7 0.33 0.09 0.0e+00 0.28 0.27 0.29 0.28 2.2e-22 1.4e-21 2.2e-23 6.1e-23
15 BLA mRNA stability Cbx7 0.38 0.11 0.0e+00 0.34 0.3 0.3 0.31 1.8e-18 3.9e-16 4.0e-16 8.7e-17
16 BLA gene expression Cbx7 0.12 0.07 9.2e-04 0.06 0.03 0.04 0.04 7.4e-04 6.4e-03 2.9e-03 2.8e-03
17 NAcc mRNA stability Cbx7 0.27 0.07 0.0e+00 0.32 0.32 0.33 0.33 7.5e-49 2.9e-49 9.9e-52 1.9e-51
18 PL gene expression Cbx7 0.12 0.06 5.1e-08 0.08 0.08 0.08 0.08 7.0e-09 4.7e-09 1.7e-09 2.1e-09
19 Liver gene expression Cbx7 0.08 0.04 4.9e-06 0.02 0.05 0.06 0.04 2.9e-03 5.7e-06 6.2e-07 4.3e-05
20 BLA alternative TSS NM_199117.2 0.12 0.07 8.2e-03 0.06 0 0.01 0.06 2.4e-04 1.9e-01 8.9e-02 3.8e-04
21 BLA alternative TSS XM_063263925.1 0.11 0.07 7.0e-03 0.07 0.01 0.05 0.06 2.2e-04 1.3e-01 8.0e-04 4.3e-04
22 pVTA intron excision ratio chr7_113356326_113358070 0.11 0.06 1.8e-03 0.02 0.04 0.03 0.03 1.1e-02 4.4e-04 1.6e-03 9.6e-04
23 RMTg mRNA stability Cbx7 0.31 0.16 1.9e-03 -0 0.05 0.05 0.04 4.7e-01 1.9e-02 2.2e-02 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.20.9-0.80.0-0.2-0.5-0.10.1-0.3-0.6-0.4-0.4-0.2-0.5-0.1-0.5-0.0-0.0-0.1-0.2-0.30.7-0.7-0.9-0.5
Area under the delay curve0.70.82.20.9-0.80.5-0.10.7-0.5-0.40.2-0.01.00.90.9-1.00.61.11.20.61.51.0-1.31.31.10.5
BMI with tail0.31.12.3-1.30.9-1.3-0.20.20.9-0.0-1.0-0.4-1.4-1.0-1.41.1-1.1-0.5-0.5-1.0-1.1-0.61.4-1.4-1.0-1.5
BMI without tail0.51.44.1-1.91.1-1.6-0.60.31.0-0.6-1.2-0.2-1.5-1.1-1.61.0-1.4-0.6-0.7-1.0-0.9-0.91.3-1.3-2.0-1.1
Body weight0.10.52.50.00.2-0.41.6-1.50.11.30.6-0.4-0.5-0.2-0.60.5-0.10.60.60.50.1-0.60.6-0.6-1.20.3
Weight adjusted by age0.20.31.8-0.50.6-0.50.20.50.5-0.1-0.11.3-0.2-0.3-0.30.4-0.1-0.4-0.4-0.2-0.00.7-1.11.10.50.6
Bone surface0.10.20.60.4-0.40.20.5-0.2-0.20.20.40.10.50.60.5-0.60.50.80.80.70.70.1-0.50.50.20.4
Bone volume0.00.00.2-0.40.0-0.1-0.00.00.1-0.0-0.2-0.0-0.10.1-0.2-0.2-0.10.40.40.20.30.40.1-0.1-0.1-0.1
Breakpoint value in progressive ratio session0.10.10.60.3-0.50.40.1-0.5-0.10.20.2-0.80.20.20.2-0.30.20.20.20.2-0.1-0.70.4-0.4-0.3-0.3
Number of licking bursts0.20.41.30.60.6-0.5-0.41.20.5-0.8-0.30.90.00.10.10.3-0.00.30.3-0.20.60.4-1.11.10.50.4
Context. condit. distance diff. score0.60.82.5-1.61.3-1.20.4-0.51.20.8-0.20.7-1.1-1.1-1.11.2-0.5-0.9-0.9-0.4-1.00.60.4-0.4-0.0-0.2
Locomotion velocity, session 12.52.75.41.4-1.11.21.9-1.2-1.21.81.90.11.92.21.9-2.31.91.71.71.91.80.3-1.61.60.91.9
Locomotion distance, session 11.21.54.00.3-0.30.40.10.8-0.4-0.20.80.91.61.61.5-1.71.31.31.31.11.70.9-2.02.01.61.0
Locomotion velocity, session 20.20.30.60.5-0.40.40.7-0.5-0.40.80.4-0.40.50.60.5-0.80.50.70.70.30.2-0.30.0-0.00.5-0.5
Locomotion distance, session 21.31.84.81.3-1.61.50.3-0.2-1.5-0.11.0-0.71.91.91.9-2.21.41.61.61.41.7-0.2-0.90.90.60.8
Locomotion velocity, session 30.91.03.8-1.41.6-1.4-0.10.91.40.0-0.51.9-0.9-0.8-0.80.8-0.4-0.7-0.7-0.5-0.31.2-1.11.11.10.3
Locomotion distance, session 32.22.47.9-1.92.2-1.9-1.12.51.9-1.2-1.02.8-0.9-0.8-0.70.9-0.6-0.6-0.6-0.80.22.1-2.12.11.80.5
Stereotopy head waving bouts, day 31.21.43.92.0-1.41.31.6-1.7-1.31.21.3-1.31.11.11.0-0.91.11.21.21.20.8-0.60.4-0.4-0.50.6
Stereotopy head waving duration, day 31.61.96.12.2-1.51.32.2-2.5-1.31.91.5-1.71.01.00.8-0.81.11.21.21.20.4-1.01.0-1.0-0.90.2
Locomotion velocity, session 70.20.21.00.10.2-0.20.3-0.10.21.00.60.40.3-0.00.10.10.5-0.2-0.20.2-0.00.5-0.40.41.00.5
Locomotion distance, session 70.91.23.21.0-0.90.80.9-0.8-0.81.41.3-0.21.21.21.2-1.21.31.01.01.41.30.6-0.90.90.71.8
Stereotopy head waving bouts, day 70.50.61.7-0.81.3-1.20.4-0.11.20.4-0.40.8-1.0-0.9-1.10.9-0.6-0.7-0.7-0.8-1.00.10.1-0.10.4-0.8
Stereotopy head waving duration, day 71.41.63.5-1.01.6-1.4-0.30.21.3-0.3-1.10.4-1.7-1.6-1.81.6-1.4-1.3-1.3-1.6-1.8-0.31.1-1.1-0.2-1.9
Locomotion velocity, session 81.11.34.70.9-0.80.71.9-1.7-0.72.21.6-0.51.01.21.0-1.41.31.11.11.30.7-0.6-0.40.40.31.0
Locomotion distance, session 80.20.32.5-1.60.5-0.4-0.2-0.20.4-0.0-0.40.3-0.6-0.5-0.60.1-0.3-0.7-0.7-0.2-0.80.10.3-0.30.1-0.5
Degree of sensitization distance3.13.210.02.0-2.62.31.7-3.2-2.32.21.6-2.91.21.21.1-1.41.20.80.81.60.2-1.81.8-1.8-1.50.6
Degree of sensitization stereotypy0.80.82.2-1.51.5-1.30.10.21.30.1-0.60.9-1.2-0.9-1.10.8-0.7-0.9-0.9-1.0-1.2-0.00.1-0.10.5-1.1
Conditioned locomotion0.10.10.5-0.3-0.40.40.5-0.4-0.40.70.2-0.10.00.1-0.0-0.30.2-0.2-0.20.2-0.2-0.4-0.00.00.10.2
Cocaine response after cond. corrected0.60.72.00.5-1.21.41.1-0.7-1.40.90.7-0.80.81.00.7-1.30.80.50.50.90.3-0.6-0.10.10.30.3
Cocaine response after cond. not corrected0.20.31.20.2-0.91.10.6-0.3-1.10.30.2-0.70.30.40.3-0.70.30.00.00.3-0.3-0.80.4-0.4-0.0-0.3
Cocaine response before conditioning1.11.32.9-1.01.1-1.2-1.51.21.2-1.4-1.40.5-1.3-1.5-1.31.7-1.2-1.0-1.0-1.4-1.10.20.7-0.7-0.3-1.3
Saline control response0.50.72.1-1.10.5-0.6-0.70.40.6-0.3-1.00.7-1.2-1.1-1.00.9-0.8-1.5-1.5-0.8-1.2-0.40.4-0.4-0.4-0.3
Bone: connectivity density0.10.10.5-0.0-0.30.10.3-0.7-0.20.50.4-0.30.30.40.3-0.60.30.30.30.60.2-0.40.2-0.2-0.60.3
Bone: cortical apparent density1.52.14.8-1.22.1-2.0-1.41.92.0-1.3-1.52.2-1.5-1.3-1.51.4-1.4-1.0-1.0-1.4-0.31.5-1.01.00.40.1
Bone: cortical area0.71.02.01.2-1.31.11.4-1.3-1.11.11.0-1.30.91.00.8-0.90.91.41.41.00.8-0.20.5-0.5-0.00.0
Bone: cortical porosity0.90.93.5-0.4-1.01.40.4-0.9-1.41.00.2-1.7-0.00.10.1-0.70.1-0.4-0.40.2-1.0-1.91.6-1.6-0.6-1.0
Bone: cortical porosity1.61.74.60.5-1.62.01.4-1.7-2.01.81.1-2.10.80.80.9-1.21.00.30.30.9-0.5-2.01.4-1.4-0.4-0.6
Bone: cortical thickness0.10.20.90.3-0.60.50.3-0.1-0.50.20.2-0.60.50.50.3-0.30.30.90.90.30.80.60.0-0.00.3-0.1
Bone: cortical thickness1.01.23.00.5-0.90.90.8-0.2-0.90.51.0-0.61.51.61.3-1.61.21.71.71.21.70.8-0.70.70.60.6
Bone: cortical tissue density1.31.84.7-1.12.0-1.9-1.21.81.9-1.1-1.32.2-1.3-1.2-1.41.3-1.3-1.0-1.0-1.2-0.31.5-1.11.10.50.2
Condit. Reinf. active minus inactive responses0.20.20.70.30.0-0.10.10.40.1-0.20.10.40.20.20.1-0.10.10.50.50.30.80.8-0.60.6-0.00.8
Condit. Reinf. active-inactive response ratio0.20.21.5-0.40.5-0.6-0.00.70.6-0.0-0.20.8-0.3-0.3-0.50.4-0.3-0.0-0.0-0.10.31.2-0.60.60.40.5
Condit. Reinf. active responses0.40.62.1-0.40.7-0.7-1.20.90.8-1.4-1.10.4-0.8-0.7-0.80.8-1.0-0.4-0.4-0.6-0.00.50.2-0.2-1.00.1
Condit. Reinf. inactive responses1.21.44.3-0.71.1-1.1-1.90.91.1-2.1-1.60.4-1.4-1.3-1.31.4-1.6-1.0-1.0-1.1-0.7-0.00.8-0.8-1.5-0.4
Incentive salience index mean0.10.10.50.10.2-0.1-0.30.50.1-0.5-0.20.30.00.0-0.1-0.1-0.20.30.30.10.60.7-0.30.3-0.30.6
Condit. Reinf. lever presses0.10.20.6-0.10.4-0.2-0.70.60.2-0.8-0.60.1-0.4-0.3-0.50.2-0.5-0.1-0.1-0.30.00.30.2-0.2-0.60.1
Condit. Reinf. active minus inactive responses2.02.64.82.0-1.51.31.5-0.9-1.31.21.9-0.52.22.11.8-2.01.71.91.91.82.00.4-1.31.30.81.7
Condit. Reinf. active-inactive response ratio1.92.13.92.0-1.41.41.6-1.2-1.41.21.8-0.91.91.91.7-1.91.61.71.71.71.60.0-0.60.60.31.3
Condit. Reinf. active responses2.02.75.32.3-1.61.41.8-1.1-1.41.42.1-0.42.21.91.8-1.61.91.91.91.71.90.5-1.41.41.31.7
Condit. Reinf. inactive responses0.81.02.91.3-0.70.51.0-0.3-0.50.91.20.21.20.91.0-0.51.11.21.20.81.30.8-1.31.31.71.0
Condit. Reinf. lever presses0.10.21.61.3-0.70.4-0.3-0.0-0.4-0.9-0.1-0.40.0-0.2-0.50.7-0.40.20.2-0.20.30.00.1-0.1-0.30.2
Condit. Reinf. lever reinforcers received1.72.35.62.4-1.81.61.6-1.3-1.61.31.9-0.72.01.71.6-1.41.61.61.61.61.60.1-1.01.01.01.5
Conditioned reinforcement - actives1.11.93.61.3-1.31.01.1-0.1-0.80.71.60.11.91.81.9-1.61.91.31.31.41.51.6-0.90.91.81.5
Conditioned reinforcement - inactives1.21.74.52.1-1.61.30.7-0.4-1.40.51.5-1.11.81.91.8-1.51.51.61.51.41.4-0.00.1-0.1-0.01.3
Conditioned locomotion1.82.44.71.8-2.21.71.6-1.4-1.81.11.8-1.81.81.91.9-1.81.81.71.71.71.1-0.50.7-0.70.10.5
Patch foraging indifference point 0 sec0.30.53.30.8-0.70.6-0.2-0.8-0.7-0.2-0.4-1.0-0.3-0.2-0.60.0-0.7-0.2-0.20.0-0.3-1.21.1-1.1-1.8-0.0
Patch foraging indifference point AUC1.62.46.51.5-0.71.10.70.6-0.80.20.90.91.31.61.5-1.21.31.81.81.12.51.7-2.62.61.62.1
Delay disc. indifference point, 0s delay0.50.52.40.7-1.00.90.3-0.5-0.80.10.1-1.50.20.10.2-0.20.10.10.30.2-0.4-0.91.4-1.4-0.8-0.7
Delay disc. indifference point, 16s delay0.60.71.50.8-0.70.6-0.20.7-0.7-0.50.20.20.90.90.9-1.00.60.80.80.51.20.7-1.21.21.20.6
Delay disc. indifference point, 2s delay0.50.62.40.3-0.70.0-0.30.70.2-0.60.0-0.40.80.80.8-0.70.50.91.00.11.01.3-0.90.91.5-0.7
Delay disc. indifference point, 24s delay2.42.78.01.5-0.70.41.30.4-0.51.01.30.91.71.71.6-1.61.61.91.91.62.40.9-2.82.81.52.2
Delay disc. indifference point, 4s delay0.40.51.30.8-0.70.60.10.4-0.6-0.20.3-0.40.80.80.8-0.80.51.11.10.61.10.3-0.70.70.50.2
Delay disc. indifference point, 8s delay0.50.51.90.7-0.50.3-0.30.5-0.3-0.50.10.20.70.60.6-0.60.40.70.80.61.41.1-1.21.20.60.9
Indifference point function ln k0.71.23.5-1.31.0-1.3-0.2-0.41.00.2-0.6-0.1-1.1-1.4-1.31.1-1.0-1.5-1.5-0.8-1.9-0.71.4-1.4-0.7-1.4
Indifference point function log k0.71.23.5-1.31.0-1.3-0.2-0.41.00.2-0.6-0.1-1.1-1.4-1.31.1-1.0-1.5-1.5-0.8-1.9-0.71.4-1.4-0.7-1.4
Patch foraging total patch changes 0 sec0.30.63.50.6-0.50.3-0.6-0.5-0.4-0.7-0.7-0.9-0.5-0.5-0.80.4-1.0-0.3-0.3-0.3-0.4-0.91.2-1.2-1.9-0.3
Patch foraging total patch changes 12 sec0.60.72.61.6-1.51.40.8-0.8-1.40.40.6-0.80.70.80.8-0.80.60.70.70.60.8-0.3-0.20.20.20.8
Patch foraging total patch changes 18 sec1.32.06.12.5-1.82.11.1-1.2-1.90.81.2-1.51.41.51.4-1.31.11.71.71.41.5-0.9-0.00.0-0.81.1
Patch foraging total patch changes 24 sec0.10.20.70.8-0.2-0.2-0.20.2-0.1-0.00.2-0.10.60.40.4-0.40.30.50.50.40.80.6-0.40.4-0.10.8
Patch foraging total patch changes 6 sec0.81.22.81.7-1.51.20.6-0.7-1.30.30.6-0.91.11.41.0-1.40.71.51.51.11.5-0.3-0.20.2-0.81.1
Patch foraging time to switch 0 sec0.40.93.2-0.2-0.80.9-0.1-0.7-0.80.4-0.2-1.6-0.2-0.20.0-0.3-0.1-0.6-0.6-0.3-1.2-1.71.8-1.8-0.4-1.6
Patch foraging water rate 0 sec0.10.21.70.30.1-0.20.2-0.5-0.0-0.10.30.10.20.40.1-0.30.00.40.40.70.6-0.1-0.00.0-1.31.2
Patch foraging water rate 12 sec0.51.13.4-0.81.0-1.8-1.10.71.1-1.2-1.10.4-1.0-1.2-1.21.1-1.4-1.0-1.0-1.0-0.9-0.40.6-0.6-1.2-0.8
Patch foraging water rate 18 sec0.10.21.20.40.0-0.9-0.1-0.10.2-0.6-0.10.3-0.0-0.1-0.20.1-0.2-0.00.00.10.1-0.5-0.00.0-1.10.7
Patch foraging water rate 24 sec0.30.41.80.20.1-0.40.2-0.60.3-0.1-0.3-0.1-0.7-0.9-1.01.0-0.9-0.5-0.5-0.3-0.7-0.80.7-0.7-1.3-0.1
Patch foraging water rate 6 sec0.81.22.3-0.81.4-1.3-1.21.01.2-1.4-1.11.3-1.1-1.3-1.51.3-1.4-1.4-1.4-1.1-0.90.0-0.30.3-0.50.1
Seeking ratio, delayed vs. immediate footshock0.50.71.5-0.80.8-0.5-1.11.20.7-1.2-1.10.4-0.9-0.8-0.90.9-1.0-0.7-0.6-1.0-0.6-0.00.4-0.4-0.4-1.0
Distance traveled before self-admin0.30.41.80.4-1.20.9-0.5-0.0-0.5-0.6-0.1-1.30.30.20.3-0.3-0.00.20.2-0.1-0.1-0.51.0-1.0-0.1-0.9
Distance traveled after self-admin1.51.94.31.7-2.11.91.0-1.6-1.70.81.3-1.71.31.31.3-1.51.01.11.11.40.7-2.00.8-0.8-1.20.8
Extensor digitorum longus weight0.62.25.7-2.31.0-1.0-2.11.41.0-2.1-2.20.0-1.6-1.2-1.20.9-1.7-1.4-1.4-1.7-1.40.01.1-1.1-1.0-2.4
Bone: elastic displacement0.10.10.20.4-0.20.20.4-0.4-0.20.30.40.20.2-0.10.20.20.2-0.0-0.00.00.0-0.4-0.40.40.00.2
Bone: elastic work1.41.84.00.9-2.01.91.8-2.0-1.91.71.3-1.71.21.21.1-1.51.21.01.01.20.3-1.10.8-0.8-0.40.1
Bone: endosteal estimation0.92.04.11.9-1.81.71.9-2.0-1.71.71.6-1.51.31.31.4-1.51.51.11.11.50.4-1.30.6-0.6-0.20.5
Bone: endosteal perimeter0.51.13.10.8-1.21.11.8-1.7-1.11.71.3-1.20.80.90.9-1.21.20.60.61.0-0.1-1.10.7-0.70.1-0.2
Epididymis fat weight0.20.64.90.0-0.2-0.31.7-1.60.02.20.9-0.6-0.30.0-0.10.10.50.40.40.7-0.10.40.6-0.6-0.00.3
Delta time in closed arm before/after self-admin0.90.81.61.2-0.71.20.7-0.2-1.30.30.6-0.10.81.00.8-0.80.91.01.00.71.21.3-0.90.91.00.7
Delta time in open arm before/after self-admin0.10.10.3-0.3-0.2-0.3-0.30.30.6-0.5-0.3-0.0-0.2-0.1-0.20.1-0.3-0.1-0.1-0.2-0.2-0.50.2-0.2-0.4-0.2
Diff in mean of infusions in LGA sessions0.91.12.51.0-0.70.21.3-0.70.21.11.2-0.01.11.21.1-1.01.21.51.51.31.60.6-1.21.20.41.4
Delay discount exponential model param0.70.82.3-0.90.7-0.50.1-0.80.40.4-0.2-0.1-0.9-0.9-0.90.9-0.6-1.1-1.2-0.6-1.5-1.01.5-1.5-1.2-0.6
Extinction: sum of active levers before priming0.80.91.90.9-1.10.31.1-0.0-0.50.91.2-0.81.21.41.2-1.31.31.31.31.00.80.1-0.30.31.20.2
Active lever presses in extinction session 60.10.10.30.1-0.30.00.40.50.30.40.4-0.50.30.40.3-0.40.30.30.30.2-0.2-0.60.4-0.40.0-0.3
Bone: final force1.42.24.42.0-2.11.91.9-1.9-1.91.21.5-1.71.51.51.4-1.41.41.81.81.41.1-0.60.3-0.30.10.3
Bone: final moment1.62.64.82.2-2.22.12.1-2.0-2.11.31.6-1.81.61.61.6-1.61.52.02.01.61.3-0.60.3-0.3-0.00.5
Food consumed during 24 hour testing period0.91.32.81.2-1.21.11.6-1.2-1.11.71.3-1.31.21.31.1-1.21.31.41.41.20.8-0.70.2-0.2-0.00.4
Glucose0.40.73.40.0-0.50.9-0.0-0.7-0.80.30.1-1.3-0.1-0.1-0.3-0.2-0.2-0.6-0.60.1-0.9-1.91.5-1.5-1.2-0.3
Heart weight1.11.75.91.6-1.20.62.1-2.4-1.11.91.4-1.60.70.80.7-0.80.91.21.21.20.1-1.81.4-1.4-1.20.3
Delay discount hyperbolic model param0.60.72.0-0.70.6-0.30.3-0.90.30.6-0.1-0.1-0.8-0.8-0.80.8-0.4-1.0-1.1-0.5-1.4-1.11.4-1.4-1.2-0.4
Intermittent access intake day 1-15 change0.20.40.9-0.60.5-0.6-0.70.30.7-0.8-0.70.3-0.5-0.7-0.60.7-0.7-0.9-1.0-0.8-0.80.40.7-0.7-0.7-0.6
Intermittent access intake escalation0.30.61.1-0.80.8-0.8-0.90.51.0-1.0-0.90.7-0.6-0.8-0.70.8-0.8-1.0-1.0-0.9-0.70.70.3-0.3-0.5-0.5
Intermittent access intake escalation 20.50.61.0-0.80.8-0.8-0.90.41.0-0.6-0.80.3-0.6-0.7-0.70.7-0.7-1.0-1.0-0.7-0.80.40.8-0.8-0.9-0.4
Intermitt. access day 1 inactive lever presses0.52.14.41.4-2.01.90.9-2.1-2.11.51.5-2.11.31.01.3-1.41.00.70.61.40.1-2.01.4-1.4-1.00.6
Intermitt. access day 15 inactive lever presses0.40.81.40.8-1.11.10.5-0.9-1.00.81.1-0.91.11.11.1-1.20.90.60.51.00.4-0.60.7-0.7-0.60.9
Intermitt. access escalation Index0.60.92.3-1.01.1-1.2-1.21.51.2-0.9-1.30.7-1.0-0.9-1.01.0-1.0-0.7-0.7-1.2-0.50.5-0.10.1-0.1-0.8
Intermittent access day 1 total infusions2.13.36.02.4-2.12.31.6-1.1-2.41.22.2-1.42.42.32.4-2.12.22.12.01.81.7-0.3-0.30.31.21.0
Intermittent access day 15 total infusions0.30.51.50.9-0.80.80.3-0.2-0.8-0.20.7-0.21.21.01.2-0.91.00.60.50.60.70.8-0.10.10.70.4
Intermittent access terminal intake (last 3 days)0.50.61.71.0-0.90.90.5-0.3-1.00.10.9-0.31.31.21.2-1.01.10.80.60.60.70.7-0.10.10.80.4
Intermittent access total infusions2.63.05.72.3-2.12.21.4-0.9-2.20.92.1-1.42.42.42.3-2.12.12.01.81.71.50.1-0.10.11.10.9
Intermittent access day 1 locomotion1.11.43.01.6-1.71.60.7-0.9-1.70.51.0-1.71.21.41.3-1.11.01.31.11.00.7-0.71.1-1.1-0.30.2
Intermittent access day 15 total locomotion0.81.43.81.9-1.31.51.1-1.1-1.61.01.4-1.31.21.41.2-1.01.21.41.31.20.9-0.60.5-0.5-0.10.6
Intermittent access total locomotion2.22.66.42.5-1.92.11.6-1.4-2.21.51.9-1.71.71.91.7-1.51.61.91.71.71.3-0.90.5-0.5-0.31.3
Intermittent access standard deviation1.63.38.61.7-2.92.81.2-2.4-2.91.11.7-2.81.81.41.8-1.71.50.60.51.5-0.1-1.92.0-2.0-0.80.2
Left kidney weight1.99.032.62.4-2.62.15.5-5.1-2.65.74.2-2.02.42.72.6-2.63.52.72.73.41.4-1.2-0.10.11.21.9
Right kidney weight2.310.334.62.8-3.02.75.9-5.8-3.05.84.5-2.72.52.62.6-2.53.52.52.63.71.2-1.90.7-0.70.22.1
Cocaine induced anxiety0.20.31.30.30.1-0.11.1-0.60.41.10.7-0.20.10.70.1-0.20.50.91.10.50.60.5-0.20.20.20.4
Post-drug Anxiety0.30.31.4-0.61.2-1.00.20.11.00.3-0.10.9-0.6-0.2-0.60.5-0.3-0.1-0.0-0.10.11.1-0.50.5-0.10.5
Baseline Anxiety0.40.41.2-0.60.9-0.6-0.90.80.3-1.0-0.81.1-0.3-0.5-0.30.3-0.4-0.7-0.8-0.5-0.01.0-0.70.70.20.2
Tail length0.10.62.5-0.80.9-0.8-0.4-0.10.7-0.5-0.40.7-0.9-0.9-1.01.0-1.0-0.6-0.7-0.4-0.3-0.70.1-0.1-1.60.6
Length with tail0.10.52.40.30.1-0.11.5-1.60.01.20.80.5-0.20.0-0.10.20.20.40.30.80.4-0.2-0.60.6-0.71.4
Length without tail0.92.88.62.5-1.61.72.9-2.9-1.62.72.1-1.21.11.31.2-1.01.61.51.51.90.9-0.8-0.10.1-0.31.4
Times rat made contact with spout0.70.82.3-0.20.1-0.20.50.20.30.40.80.61.00.90.8-0.40.91.31.31.11.50.9-1.21.20.21.4
Lifetime Intake3.74.57.92.7-2.62.71.9-1.1-2.71.42.5-1.82.82.82.8-2.62.62.42.32.21.9-0.1-0.10.11.41.1
Liver weight, left0.40.62.0-1.41.0-0.80.20.80.90.7-0.11.3-0.5-0.3-0.50.3-0.0-0.5-0.5-0.2-0.11.0-1.21.21.30.2
Liver weight, right1.22.15.2-2.32.0-1.4-0.30.71.90.3-0.91.6-2.0-1.9-2.12.0-1.4-1.7-1.7-1.4-1.50.4-0.10.10.1-0.6
Locomotor activity0.10.21.5-0.2-0.40.11.2-1.0-0.31.10.4-0.3-0.10.3-0.2-0.20.30.40.40.30.0-0.20.3-0.3-0.40.1
Locomotor testing distance0.10.20.5-0.70.3-0.3-0.30.50.3-0.3-0.70.4-0.7-0.4-0.70.5-0.5-0.1-0.1-0.4-0.10.30.1-0.1-0.4-0.2
Locomotor testing rearing0.10.31.5-0.2-0.60.91.0-0.8-0.61.20.6-0.50.40.40.3-0.40.50.40.30.50.0-0.20.2-0.20.1-0.0
Locomotion in novel chamber3.34.27.2-2.62.4-2.7-2.52.52.2-2.4-2.41.8-2.2-2.1-2.22.1-2.2-2.2-2.2-2.3-1.80.60.4-0.4-0.4-1.4
Locomotion in novel chamber post-restriction0.61.02.6-1.11.1-1.3-1.41.61.0-1.3-1.20.6-0.8-0.8-0.81.0-0.8-0.7-0.8-1.2-0.61.00.1-0.10.4-1.1
Fecal boli incidents, locomotor time 11.62.36.12.2-1.62.41.2-1.2-2.51.11.4-1.11.71.61.7-1.61.51.61.61.51.4-1.1-0.30.3-0.41.4
Change in fecal boli incidents, locomotor task1.31.35.0-0.50.8-1.30.90.11.20.80.42.00.10.20.1-0.20.50.40.30.30.91.9-2.22.21.61.4
Time >=10cm from walls, locomotor time 11.31.32.51.5-1.41.51.6-1.3-1.51.31.3-1.01.21.11.2-1.31.21.20.81.20.6-1.20.2-0.2-0.30.7
Bouts of movement, locomotor time 10.50.51.10.5-0.00.31.10.3-0.11.00.90.30.60.70.6-0.60.90.60.80.90.50.1-1.01.01.01.0
Total resting periods, locomotor time 10.60.71.40.9-0.50.61.20.1-0.51.11.1-0.20.90.90.9-0.81.10.91.01.00.7-0.1-0.70.70.70.9
Rest time, locomotor task time 11.01.32.81.1-1.21.11.4-1.5-0.81.71.6-1.11.21.31.2-1.11.31.31.11.41.00.00.0-0.00.01.0
Distance moved, locomotor task time 10.71.02.0-1.41.0-1.2-0.80.41.3-0.8-1.10.7-1.2-1.2-1.21.1-1.1-1.2-1.2-1.1-1.10.50.4-0.4-0.2-1.1
Vertical activity count, locomotor time 10.10.31.6-0.40.5-0.5-0.3-0.10.7-0.1-0.50.1-0.6-0.7-0.60.6-0.6-0.7-0.5-0.3-0.6-0.70.6-0.6-1.30.2
Time >=10cm from walls, locomotor time 20.20.22.30.7-0.60.40.5-0.4-0.40.50.4-0.40.20.20.2-0.20.10.30.10.2-0.1-1.50.3-0.3-0.60.3
Bouts of movement, locomotor time 20.30.51.6-0.60.7-0.8-0.61.30.8-0.4-0.60.1-0.4-0.6-0.41.0-0.3-0.3-0.3-0.9-0.60.70.2-0.20.9-1.2
Total resting periods, locomotor time 20.10.21.0-0.10.3-0.4-0.30.90.4-0.2-0.2-0.1-0.0-0.1-0.00.50.00.20.2-0.5-0.10.70.0-0.01.0-0.9
Rest time, locomotor task time 20.91.11.90.7-0.90.80.8-1.3-0.81.01.3-0.11.21.21.2-1.31.11.11.11.21.40.9-0.90.90.71.2
Distance moved, locomotor task time 20.50.61.3-1.00.4-0.6-0.40.10.8-0.5-0.70.1-1.0-1.0-1.00.9-0.9-1.0-1.1-0.8-1.00.00.7-0.7-0.5-0.7
Vertical activity count, locomotor time 20.10.20.80.3-0.10.30.3-0.8-0.10.40.1-0.3-0.3-0.3-0.30.4-0.2-0.2-0.1-0.0-0.3-0.80.6-0.6-0.90.3
Light reinforcement 10.00.10.70.50.00.80.0-0.1-0.3-0.10.2-0.40.50.20.2-0.20.10.30.30.10.1-0.40.2-0.2-0.5-0.3
Light reinforcement 20.50.82.3-1.30.7-0.2-0.50.70.5-0.3-1.00.0-1.1-1.0-1.30.9-1.0-1.0-1.0-1.2-1.30.20.7-0.70.3-1.5
Bone: marrow area1.02.24.32.0-1.91.82.0-2.1-1.81.71.6-1.51.41.31.5-1.61.61.21.21.60.5-1.30.5-0.5-0.20.6
Bone: maximum diameter1.62.97.32.0-1.91.82.7-2.5-1.82.22.1-1.91.61.71.5-1.71.81.91.91.80.9-0.90.6-0.6-0.10.4
Bone: maximum force2.44.37.32.4-2.72.52.7-2.4-2.52.02.3-2.12.22.32.1-2.32.12.62.62.21.8-0.60.2-0.20.10.9
Bone: maximum moment2.74.87.92.5-2.82.62.8-2.5-2.62.22.4-2.22.32.42.2-2.42.22.82.82.41.9-0.60.1-0.10.01.0
Mean time between licks in bursts0.51.23.7-0.90.5-0.7-1.41.40.7-1.7-1.40.2-0.9-1.0-1.11.0-1.2-1.0-1.0-1.5-1.2-0.60.7-0.7-0.3-1.9
Mean num. licks in bursts0.20.31.1-0.6-0.30.10.9-0.8-0.11.10.9-0.10.70.50.5-0.50.70.50.50.90.50.6-0.10.10.10.7
Cd content in liver0.91.04.00.30.6-0.31.10.30.50.60.61.40.50.70.4-0.30.61.21.20.61.41.4-2.02.01.11.1
Co content in liver0.30.31.00.5-0.60.60.30.6-0.5-0.10.2-0.40.70.70.5-0.50.41.01.00.40.7-0.8-0.20.2-0.40.2
Cu content in liver1.41.77.6-0.81.0-1.1-2.31.71.1-2.8-2.00.4-1.2-0.9-1.41.0-1.8-0.5-0.5-1.5-0.30.30.5-0.5-1.0-1.3
Fe content in liver1.21.56.91.5-1.21.21.5-1.7-1.21.20.6-1.70.10.50.2-1.00.10.60.60.6-0.3-2.61.5-1.5-1.9-0.2
K content in liver0.20.20.7-0.80.10.2-0.70.50.1-0.5-0.40.2-0.3-0.3-0.30.0-0.4-0.7-0.7-0.3-0.5-0.50.2-0.2-0.0-0.2
Mg content in liver0.10.10.7-0.4-0.20.4-0.4-0.4-0.1-0.2-0.1-0.4-0.00.2-0.0-0.5-0.1-0.1-0.10.1-0.2-0.80.5-0.5-0.4-0.2
Mn content in liver0.30.41.7-0.50.6-0.0-0.50.60.5-0.4-0.41.0-0.4-0.5-0.40.7-0.2-0.3-0.3-0.50.21.1-0.90.91.30.1
Na content in liver0.40.41.5-0.40.2-0.1-0.7-0.40.1-0.8-0.6-0.2-0.5-0.3-0.40.1-0.7-0.6-0.6-0.3-0.7-1.21.0-1.0-1.2-0.4
Rb content in liver0.70.82.11.4-0.80.60.7-0.3-0.80.30.8-0.71.11.21.0-1.20.81.41.40.91.2-0.3-0.50.50.20.5
Se content in liver1.72.03.7-1.31.7-1.4-1.41.01.8-1.9-1.81.6-1.8-1.5-1.71.7-1.7-1.1-1.1-1.7-0.71.6-0.20.2-0.0-1.1
Sr content in liver2.72.35.7-2.11.5-1.8-2.41.51.5-2.4-2.01.1-1.5-1.4-1.51.6-1.8-1.3-1.3-1.6-0.61.80.1-0.1-0.3-0.9
Zn content in liver0.20.20.9-0.50.4-0.5-0.10.60.5-0.3-0.20.7-0.10.0-0.2-0.1-0.20.10.10.00.40.9-0.70.70.20.3
Bone: minimum diameter0.71.22.21.1-1.41.31.4-1.3-1.31.51.2-1.31.01.11.0-1.21.11.21.21.20.7-0.50.4-0.40.00.4
Time in familiar zone, hab. session 11.11.02.11.5-0.50.41.0-0.3-0.40.80.90.31.01.11.1-1.01.11.41.41.01.40.6-1.31.31.01.0
Time in novel zone, hab. session 11.01.02.5-1.30.2-0.1-0.3-0.30.1-0.1-0.5-0.7-0.8-0.9-0.80.7-0.8-1.2-1.2-0.7-1.6-1.51.6-1.6-1.4-1.2
Total zone transitions, hab. session 11.62.27.2-1.41.9-1.9-1.62.41.9-2.0-1.32.7-0.8-0.8-0.90.9-0.9-0.6-0.6-1.00.31.7-1.91.91.10.3
Total locomotion distance, hab. session 11.11.66.1-1.21.7-1.7-1.01.81.7-1.2-0.82.5-0.7-0.9-0.80.9-0.6-0.8-0.8-0.7-0.01.3-1.71.71.10.5
Locomotion velocity, hab. session 10.81.24.4-0.91.4-1.5-1.01.61.5-1.3-0.72.1-0.5-0.6-0.60.6-0.5-0.5-0.5-0.50.21.4-1.51.50.90.5
Time in familiar zone, hab. session 21.21.32.3-1.31.5-1.5-1.21.31.5-1.0-1.21.4-1.3-1.3-1.21.3-1.2-1.1-1.1-1.2-0.80.7-0.40.40.6-0.7
Time in novel zone, hab. session 21.31.32.50.8-1.61.51.1-1.3-1.51.11.2-1.31.21.41.2-1.51.21.01.01.30.8-0.80.3-0.3-0.70.9
Total zone transitions, hab. session 20.91.22.91.3-0.60.70.5-0.1-0.7-0.00.90.21.41.41.4-1.51.21.41.41.21.70.4-1.21.20.41.4
Total locomotion distance, hab. session 20.50.61.90.8-1.11.20.3-0.4-1.20.10.6-0.51.11.01.0-1.40.90.70.70.80.7-0.6-0.30.3-0.00.6
Locomotion velocity, hab. session 20.50.71.71.1-1.11.20.2-0.3-1.2-0.10.6-0.51.11.01.1-1.30.80.70.70.80.8-0.6-0.30.3-0.10.7
Novel to familiar place preference ratio0.20.20.8-0.90.7-0.70.7-0.20.70.20.10.6-0.3-0.1-0.40.3-0.2-0.0-0.0-0.1-0.20.0-0.10.1-0.60.1
Novelty place preference0.30.31.2-1.11.0-1.00.7-0.11.00.30.11.0-0.5-0.2-0.60.5-0.3-0.1-0.1-0.2-0.10.3-0.40.4-0.40.2
Time in novel zone, NPP test0.30.41.3-1.01.0-1.10.8-0.11.10.30.11.0-0.5-0.3-0.60.6-0.30.10.1-0.2-0.00.5-0.40.4-0.40.2
Total zone transitions, NPP test0.81.14.7-0.50.8-0.8-0.81.50.8-1.2-0.32.00.30.30.1-0.40.10.10.10.01.01.2-2.22.21.21.1
Total locomotion distance, NPP test0.30.51.90.4-0.30.2-0.00.3-0.2-0.30.40.90.80.60.5-0.80.60.30.30.50.90.4-1.41.40.81.1
Locomotion velocity, NPP test0.20.31.50.0-0.10.0-0.50.7-0.1-0.6-0.10.90.50.30.2-0.60.2-0.0-0.00.20.60.5-1.21.20.90.7
Intraocular pressure0.40.51.60.6-0.30.21.1-0.7-0.21.21.00.20.70.60.4-0.40.60.60.60.50.70.2-1.21.21.10.6
Delta distance traveled before/after self-admin1.51.64.31.2-0.80.91.9-1.7-1.21.81.6-0.01.11.21.1-1.31.31.11.21.61.2-0.8-0.70.7-0.52.1
Delta ambulatory time before/after self-admin1.92.35.01.6-1.11.22.2-1.7-1.51.91.9-0.11.51.61.5-1.71.61.51.52.01.4-0.9-1.01.0-0.32.2
Parametrial fat weight0.61.43.3-1.61.7-1.5-0.90.91.5-0.4-1.21.2-1.7-1.5-1.81.4-1.5-1.2-1.2-1.1-0.80.3-0.10.1-0.6-0.1
Pavlov. Cond. lever latency0.10.10.30.2-0.0-0.00.5-0.5-0.00.50.40.10.30.40.4-0.20.30.40.40.40.40.2-0.30.30.10.3
Pavlov. Cond. magazine entry latency0.10.20.50.3-0.60.6-0.20.6-0.6-0.40.2-0.30.60.40.7-0.40.60.40.40.00.3-0.2-0.20.20.7-0.2
Pavlov. Cond. change in total contacts0.40.41.00.9-1.00.9-0.10.3-0.9-0.40.2-0.60.80.80.8-0.70.61.01.00.40.9-0.1-0.20.20.30.1
Pavlov. Cond. index score0.20.20.70.5-0.80.80.10.2-0.80.00.4-0.50.60.50.6-0.50.60.40.40.30.4-0.3-0.10.10.40.2
Pavlov. Cond. latency score0.10.10.30.2-0.50.6-0.10.3-0.6-0.10.1-0.40.30.20.3-0.20.30.10.10.00.0-0.40.2-0.20.1-0.1
Pavlov. Cond. lever contacts0.10.10.6-0.2-0.20.2-0.80.6-0.2-0.7-0.5-0.3-0.2-0.3-0.30.1-0.3-0.4-0.4-0.4-0.3-0.30.4-0.4-0.2-0.3
Pavlov. Cond. magazine entry number0.20.30.9-0.40.5-0.60.2-0.70.60.3-0.30.0-0.7-0.5-0.80.4-0.7-0.6-0.6-0.2-0.7-0.40.7-0.7-0.9-0.3
Pavlov. Cond. intertrial magazine entries0.20.31.40.8-0.1-0.1-0.1-0.30.1-0.4-0.10.00.10.50.1-0.5-0.10.70.70.60.90.1-0.20.2-1.21.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.4-0.50.6-0.10.4-0.6-0.20.3-0.20.50.30.5-0.30.40.40.40.10.4-0.0-0.30.30.50.1
Pavlov. Cond. response bias0.10.20.40.5-0.50.6-0.30.4-0.6-0.40.2-0.30.50.30.5-0.30.40.30.30.00.40.1-0.20.20.60.0
Pavlov. Cond. lever latency0.60.82.5-0.70.8-0.60.60.50.60.70.51.20.50.61.1-0.71.00.60.60.50.81.3-1.41.41.60.6
Pavlov. Cond. magazine entry latency0.50.51.81.4-1.21.2-0.3-0.5-1.2-0.7-0.1-1.10.40.50.1-0.4-0.20.50.50.30.6-0.90.5-0.5-1.10.3
Pavlov. Cond. change in total contacts2.03.28.22.9-2.72.51.6-2.7-2.51.31.6-2.51.51.30.8-1.30.81.21.21.50.6-2.41.2-1.2-1.80.8
Pavlov. Cond. index score0.40.61.81.1-1.31.2-0.1-0.8-1.2-0.50.1-1.20.30.2-0.3-0.0-0.30.10.10.20.1-1.20.8-0.8-1.30.3
Pavlov. Cond. latency score0.40.61.81.2-1.31.2-0.2-0.8-1.3-0.50.1-1.20.40.3-0.2-0.1-0.30.10.10.30.2-1.20.7-0.7-1.30.4
Pavlov. Cond. lever contacts0.60.93.00.7-0.70.5-0.6-0.4-0.5-0.9-0.6-1.1-0.6-0.7-1.20.9-1.1-0.7-0.7-0.6-0.8-1.31.4-1.4-1.7-0.6
Pavlov. Cond. magazine entry number0.20.30.9-0.80.9-0.90.10.70.90.4-0.00.7-0.3-0.30.20.20.2-0.2-0.2-0.2-0.30.8-0.40.40.9-0.4
Pavlov. Cond. intertrial magazine entries0.81.23.20.5-0.70.71.2-0.7-0.71.81.2-0.41.01.31.4-1.31.61.41.41.31.20.6-0.50.50.81.0
Pavlov. Cond. lever-magazine prob. diff.0.40.62.11.0-1.31.1-0.3-0.7-1.1-0.6-0.1-1.20.1-0.0-0.40.1-0.5-0.1-0.10.0-0.1-1.21.0-1.0-1.40.0
Pavlov. Cond. response bias0.50.72.01.1-1.31.1-0.2-0.9-1.1-0.4-0.1-1.40.10.0-0.60.1-0.60.00.0-0.1-0.2-1.41.1-1.1-1.4-0.2
Time in closed arm before self-admin1.31.75.90.20.1-0.1-1.60.00.0-1.2-1.3-1.2-0.9-1.1-0.91.0-1.3-1.0-0.9-1.0-1.3-2.02.3-2.3-2.4-1.4
Time in closed arm after self-admin0.30.31.21.1-0.40.90.4-0.7-0.90.70.4-0.70.40.50.4-0.30.30.60.60.60.50.10.4-0.4-0.70.5
Time in open arm before self-admin0.40.42.1-0.90.7-0.5-0.2-0.10.2-0.2-0.11.2-0.3-0.3-0.30.2-0.1-0.5-0.6-0.20.21.5-1.01.00.90.5
Time in open arm after self-admin1.01.12.0-1.41.0-1.4-1.11.21.4-1.2-1.21.2-1.2-1.1-1.21.1-1.2-1.0-1.0-1.2-0.60.4-0.40.40.3-0.5
Bone: periosteal estimation1.12.24.52.0-1.91.82.1-2.1-1.81.81.6-1.81.41.41.4-1.51.51.61.61.50.7-1.00.6-0.6-0.10.3
Bone: periosteal perimeter1.11.95.61.2-1.61.52.4-2.2-1.52.21.7-1.61.11.21.1-1.51.51.11.11.40.3-1.00.7-0.70.10.1
Bone: post-yield work2.13.17.12.1-1.31.22.0-1.3-1.21.32.1-0.82.32.32.1-1.92.12.72.72.02.30.2-1.11.10.41.4
Progressive ratio test 1 active lever presses2.32.94.92.2-2.12.11.5-0.9-2.10.91.8-1.22.12.22.1-2.01.92.12.01.61.90.2-0.60.61.10.9
Progressive ratio test 1 breakpoint2.22.64.42.1-2.02.01.4-0.8-1.90.81.8-1.02.12.12.1-1.91.92.01.91.61.90.4-0.80.81.21.0
Progressive ratio test 1 inactive lever presses2.13.06.72.2-2.52.40.9-1.6-2.50.91.6-2.62.02.02.1-2.01.71.81.61.61.0-1.21.2-1.2-0.30.1
Progressive ratio test 2 active lever presses2.83.25.82.1-1.81.81.5-0.5-1.81.32.2-0.62.42.32.4-2.22.32.02.01.92.00.6-1.11.11.81.8
Progressive ratio test 2 breakpoint2.73.15.72.0-1.71.71.4-0.4-1.71.22.1-0.52.42.22.4-2.22.32.01.91.82.00.7-1.21.21.91.7
Progressive ratio test 2 inactive lever presses0.30.61.31.0-1.00.7-0.10.4-0.80.00.8-0.31.21.11.1-1.00.90.70.60.60.70.2-0.20.20.80.7
Incentive Sensitization - Responses0.30.41.50.4-0.20.20.10.4-0.20.40.80.60.90.60.8-0.70.90.40.30.60.60.4-0.90.91.21.1
Incentive Sensitization - Breakpoint0.40.51.60.4-0.30.30.30.3-0.30.60.90.41.00.71.0-0.81.00.50.40.70.60.4-0.90.91.31.1
Sum of active levers in priming session hrs 5-60.10.10.4-0.50.0-0.4-0.10.00.6-0.20.1-0.2-0.2-0.1-0.20.0-0.3-0.2-0.2-0.2-0.3-0.40.5-0.5-0.5-0.3
Progressive ratio0.20.30.90.7-0.71.00.3-0.7-0.80.20.4-0.90.50.40.4-0.60.30.30.30.60.1-0.70.7-0.7-0.90.1
Food seeking constrained by brief footshock0.40.51.51.1-0.50.30.9-0.4-0.40.60.6-0.30.80.90.8-0.50.81.21.20.61.00.4-0.50.50.70.1
Seeking ratio, punishment vs. effort0.20.20.80.5-0.2-0.30.5-0.10.00.50.3-0.00.40.50.4-0.20.50.70.70.20.70.4-0.70.70.90.1
Retroperitoneal fat weight0.21.07.70.3-0.1-0.02.5-1.8-0.22.81.1-0.5-0.20.2-0.4-0.10.50.90.90.70.30.40.0-0.00.50.3
Reaction time number correct1.01.94.7-1.61.6-1.8-1.42.21.8-1.0-1.22.1-1.2-1.3-1.31.3-1.1-1.3-1.2-1.5-0.71.2-1.01.01.5-0.4
Reaction time mean minus median0.10.21.1-0.9-0.30.2-0.2-0.5-0.2-0.0-0.1-0.4-0.20.00.2-0.50.0-0.5-0.50.1-0.6-1.00.7-0.7-0.5-0.4
Reaction time mean minus median AUC0.10.31.5-1.2-0.0-0.2-0.0-0.70.00.40.1-0.4-0.3-0.10.1-0.30.1-0.8-0.70.1-0.9-0.90.8-0.8-0.4-0.4
Reaction time num false alarms0.40.61.5-0.30.5-1.2-0.40.10.5-0.5-0.70.1-0.8-0.9-0.91.0-0.9-0.9-0.9-0.8-1.0-0.60.8-0.8-0.8-0.6
Reaction time num false alarms AUC0.30.52.0-0.10.7-1.4-0.50.40.7-0.7-0.70.5-0.8-0.9-1.01.1-0.8-0.9-0.9-0.8-0.8-0.10.4-0.4-0.5-0.4
Reaction time trials correct on left1.01.94.7-1.61.6-1.8-1.42.21.8-1.0-1.22.1-1.2-1.3-1.31.3-1.1-1.3-1.2-1.5-0.71.2-1.01.01.5-0.4
Reaction time trials on left1.12.04.9-1.71.6-1.8-1.52.21.8-1.0-1.22.1-1.2-1.3-1.31.3-1.1-1.3-1.3-1.5-0.71.2-1.11.11.6-0.4
Reaction time mean0.20.41.5-0.7-0.20.3-0.3-0.6-0.1-0.2-0.2-0.7-0.3-0.20.1-0.2-0.2-0.7-0.7-0.0-1.0-1.21.1-1.1-0.9-0.6
Reaction time mean AUC0.10.20.7-0.7-0.10.2-0.2-0.4-0.0-0.1-0.1-0.4-0.2-0.10.1-0.3-0.0-0.6-0.60.1-0.7-0.80.7-0.7-0.5-0.4
Median of all reaction times0.20.31.1-0.6-0.20.2-0.4-0.4-0.1-0.4-0.3-0.6-0.3-0.3-0.0-0.1-0.3-0.7-0.7-0.2-0.9-1.01.0-1.0-0.7-0.7
Reaction time omissions0.20.21.0-1.00.10.2-0.60.90.1-0.5-0.50.4-0.00.10.2-0.50.0-0.4-0.4-0.3-0.3-0.3-0.30.31.0-0.7
Reaction time false alarm rate0.20.31.50.30.1-0.7-0.0-0.40.0-0.4-0.4-0.5-0.5-0.4-0.50.6-0.5-0.4-0.4-0.3-0.6-0.61.0-1.0-1.2-0.5
Reaction time premature initiation rate1.52.15.11.0-1.91.41.2-1.9-1.81.71.3-2.11.31.51.5-2.31.30.90.91.60.3-1.71.1-1.1-1.20.4
Reaction time premature initiations0.40.62.60.2-1.00.40.6-0.9-0.91.40.8-1.00.80.90.8-1.60.80.30.31.00.1-0.90.4-0.4-0.30.4
Std. dev. reaction times0.10.31.4-0.6-0.20.30.2-0.9-0.20.40.2-0.4-0.20.00.2-0.50.1-0.5-0.50.3-0.7-1.20.8-0.8-0.6-0.1
Reaction time trials completed1.12.04.9-1.71.6-1.8-1.52.21.8-1.0-1.22.1-1.2-1.3-1.31.3-1.1-1.3-1.3-1.5-0.71.2-1.11.11.6-0.4
Reaction time trials AUC0.81.63.7-1.41.4-1.7-1.21.91.6-0.7-1.01.9-1.1-1.2-1.21.2-1.0-1.1-1.1-1.3-0.71.1-0.90.91.5-0.3
Run reversals in cocaine runway, females0.40.41.7-0.71.3-1.0-0.50.51.1-0.1-0.30.9-0.6-0.6-0.60.7-0.5-0.5-0.4-0.5-0.2-0.5-0.50.5-0.20.1
Run reversals in cocaine runway, males2.12.15.60.6-0.20.51.5-0.3-0.41.01.31.01.41.51.4-1.41.51.31.31.51.92.4-2.32.31.72.0
Latency to leave start box in cocaine runway0.20.31.3-0.80.3-0.3-0.20.20.2-0.2-0.3-0.0-0.4-0.6-0.40.3-0.3-0.8-0.7-0.5-1.00.10.4-0.40.5-1.1
Latency to leave start box in cocaine runway, F0.10.11.1-0.1-0.0-0.0-0.20.3-0.2-0.5-0.4-0.1-0.2-0.2-0.1-0.1-0.2-0.4-0.3-0.4-0.50.10.2-0.20.5-1.0
Latency to leave start box in cocaine runway, M0.40.41.7-1.30.5-0.5-0.1-0.00.60.2-0.10.2-0.6-0.8-0.60.6-0.4-0.9-0.9-0.5-1.1-0.30.5-0.50.2-0.6
Std. dev. time between licks in bursts0.20.21.51.2-0.70.5-0.30.4-0.5-0.7-0.2-0.40.1-0.0-0.00.0-0.20.10.10.00.0-1.10.4-0.4-0.90.0
Total sessions with >9 infusions3.84.78.12.5-2.82.62.5-1.8-2.62.22.5-2.22.42.62.4-2.42.52.52.52.31.8-0.40.1-0.11.00.9
Short access day 1 total inactive lever presses5.26.813.03.6-3.33.32.4-2.9-3.51.82.7-2.92.82.82.8-2.82.42.62.72.91.8-2.71.0-1.0-1.41.6
Short access day 10 total inactive lever presses0.30.82.81.0-0.50.81.0-1.7-0.81.51.3-0.60.80.70.7-0.60.80.60.61.20.6-0.40.1-0.1-0.71.5
Short access day 1 total infusions1.92.55.31.8-2.12.21.4-1.4-2.31.31.7-2.01.61.71.7-1.71.61.51.61.70.9-1.50.8-0.8-0.20.8
Short access day 10 total infusions2.32.95.72.0-2.42.11.8-1.9-2.11.52.0-2.12.02.02.1-1.92.01.81.71.71.1-0.30.6-0.60.60.4
Short access total infusions4.05.18.42.8-2.92.82.3-1.8-2.82.02.6-2.42.72.82.7-2.62.62.72.62.41.8-0.70.3-0.30.90.9
Short access day 1 locomotion1.01.33.80.7-2.01.70.7-1.4-1.60.70.9-1.90.80.90.9-1.00.70.50.60.90.0-1.51.5-1.5-0.90.1
Short access day 10 total locomotion1.01.96.61.0-2.21.7-0.1-1.8-1.90.20.7-2.60.70.30.7-0.60.3-0.1-0.10.8-0.4-2.02.3-2.3-1.9-0.1
Short access total locomotion1.72.16.61.4-2.62.00.8-1.8-2.10.91.1-2.61.11.01.2-1.10.90.80.81.10.2-1.51.9-1.9-1.0-0.1
One hour access (0.3 mA shock)0.50.61.70.7-0.71.0-0.30.7-0.9-0.70.5-0.51.11.01.0-0.70.80.60.50.20.41.30.5-0.51.0-0.2
Compulsive drug intake1.21.57.3-0.10.7-0.40.21.10.50.20.21.60.40.60.4-0.40.50.70.80.51.61.9-2.72.71.41.9
One hour access (shock baseline)0.40.73.80.6-0.60.8-0.4-0.0-0.8-0.70.0-1.20.40.20.4-0.10.2-0.1-0.1-0.3-0.8-0.41.9-1.9-0.1-1.4
Social response proportion1.41.65.8-1.0-0.71.0-0.3-0.6-0.8-0.4-0.8-1.6-0.7-0.4-0.8-0.0-0.9-0.8-0.8-0.8-1.7-2.42.3-2.3-1.4-2.3
Social responses0.20.20.70.8-0.70.90.4-0.2-0.8-0.20.1-0.30.50.60.5-0.60.40.50.50.20.4-0.3-0.30.30.10.0
Social time0.30.41.50.0-1.01.2-0.80.1-1.1-1.0-0.6-0.90.20.20.1-0.5-0.1-0.2-0.2-0.2-0.2-1.10.5-0.5-0.4-0.7
Soleus weight0.61.75.51.0-1.01.00.8-0.5-1.01.11.40.11.61.41.8-1.71.71.01.01.71.50.6-1.31.30.52.3
Bone: stiffness1.42.35.01.9-2.12.01.8-2.1-2.01.31.3-2.21.21.31.3-1.31.21.61.61.40.8-1.21.1-1.1-0.80.1
Tibialis anterior weight0.20.83.9-1.20.3-0.4-1.91.70.4-2.0-1.5-0.0-0.5-0.3-0.30.1-0.9-0.4-0.4-0.8-0.10.70.3-0.3-0.5-1.1
Time to tail flick, vehicle, before self-admin0.20.30.60.5-0.30.30.6-0.6-0.50.60.7-0.30.60.70.6-0.80.60.40.40.70.3-0.30.0-0.0-0.40.5
Time to tail flick, vehicle, after self-admin0.10.21.60.20.1-0.4-0.10.10.1-0.3-0.10.3-0.1-0.3-0.10.1-0.3-0.4-0.30.2-0.3-1.0-0.00.0-1.30.7
Time to tail flick, test, before self-admin0.40.42.8-0.90.7-0.8-0.10.70.70.3-0.10.60.10.10.1-0.30.20.1-0.1-0.10.41.7-0.90.91.30.0
Time to tail flick, test, after self-admin0.40.51.0-0.40.8-0.9-0.81.00.4-0.7-0.90.6-0.9-0.7-0.90.9-0.9-0.6-0.6-0.9-0.40.1-0.20.2-0.1-0.3
Delta time to tail flick, vehicle, before/after SA0.20.21.50.7-0.80.60.1-0.1-0.6-0.10.0-0.80.20.10.2-0.10.00.20.20.2-0.1-1.20.5-0.5-0.80.0
Delta time to tail flick, test, before/after SA1.51.62.8-0.41.1-1.0-1.61.50.9-1.7-1.60.7-1.5-1.4-1.51.7-1.7-1.2-1.1-1.5-1.1-1.10.6-0.6-1.3-0.7
Tibia length1.02.65.61.8-1.31.22.4-1.5-1.21.72.1-0.22.01.81.9-1.71.92.02.01.81.70.2-1.21.21.21.4
Ambulatory time before self-admin0.10.20.8-0.1-0.60.4-0.90.50.1-0.9-0.5-0.6-0.2-0.2-0.20.2-0.4-0.2-0.2-0.4-0.2-0.10.6-0.6-0.1-0.8
Ambulatory time after self-admin0.50.62.51.2-1.21.00.5-0.6-0.9-0.10.6-0.50.80.70.8-0.90.50.60.60.80.5-1.60.0-0.0-0.90.8
Bone: tissue strength0.20.20.50.6-0.20.20.7-0.3-0.20.50.60.20.40.30.2-0.20.30.40.40.30.40.2-0.60.60.50.6
Total heroin consumption0.80.91.71.1-0.70.81.00.0-0.70.50.9-0.21.21.31.2-1.21.21.31.30.91.20.3-0.80.81.10.7
Bone: trabecular number0.20.32.0-1.40.8-0.8-0.30.50.8-0.1-0.40.7-0.5-0.4-0.60.1-0.4-0.5-0.5-0.3-0.30.5-0.30.30.2-0.2
Bone: trabecular spacing2.63.56.72.6-1.92.02.2-1.7-2.02.22.3-1.22.22.12.1-2.02.12.32.31.91.8-0.4-0.50.50.61.4
Bone: trabecular thickness1.61.95.1-2.31.2-1.2-1.71.01.2-1.1-1.80.2-1.8-1.6-1.71.3-1.6-1.5-1.5-1.4-1.50.21.3-1.3-0.8-1.3
Bone: trabecular tissue density1.42.15.6-0.61.0-0.9-1.80.80.9-1.9-1.8-0.2-1.6-1.5-1.61.3-1.9-1.2-1.2-1.4-1.3-1.01.7-1.7-2.4-1.4
Water consumed over 24 hours0.60.92.20.4-0.60.60.9-0.4-0.60.71.0-0.11.11.11.0-0.71.01.41.41.31.4-0.0-0.80.8-0.31.5
Number of responses in last shaping day2.02.27.41.6-2.52.30.1-1.1-2.30.00.8-2.71.31.11.4-1.40.90.70.80.7-0.1-1.62.1-2.1-0.5-1.0