Hub : Genes

Cbx6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Cbx6 0.08 0.04 9.3e-08 0.05 0.05 0.03 0.05 1.4e-06 7.3e-06 1.1e-04 4.5e-06
2 NAcc mRNA stability Cbx6 0.03 0.02 2.6e-03 0.01 0.01 0.01 0.02 9.2e-03 1.8e-02 4.4e-03 6.5e-04
3 IC mRNA stability Cbx6 0.11 0.06 3.4e-03 0.07 0.02 0.01 0.03 6.7e-04 5.5e-02 9.9e-02 1.4e-02
4 BLA mRNA stability Cbx6 0.06 0.04 9.3e-03 0.02 0.01 0.01 0.01 2.1e-02 1.1e-01 1.1e-01 1.4e-01
5 PL gene expression Cbx6 0.03 0.02 9.5e-03 0.01 0.02 0.01 0.01 1.2e-02 5.3e-03 8.0e-03 3.2e-02
6 Brain mRNA stability Cbx6 0.06 0.04 2.2e-03 0 0.02 0.01 0.02 1.3e-01 1.1e-02 2.2e-02 7.4e-03
7 Adipose gene expression Cbx6 0.06 0.03 2.5e-06 0.03 0.04 0.04 0.04 1.2e-04 5.9e-05 3.2e-05 6.7e-05
8 Brain gene expression Cbx6 0.07 0.04 1.6e-04 0.04 0.05 0.05 0.04 9.5e-05 8.3e-06 3.0e-05 1.5e-04
9 IL mRNA stability Cbx6 0.25 0.11 7.6e-03 0.01 0.03 0.02 0.03 2.1e-01 6.7e-02 1.2e-01 5.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.10.3-0.00.1-0.10.1-0.0-0.5-0.30.2-0.5
Area under the delay curve1.82.77.6-2.81.9-2.2-1.61.21.9-0.80.7-0.3
BMI with tail0.31.23.11.8-1.51.00.1-1.2-1.11.1-0.20.7
BMI without tail0.20.92.51.6-1.00.90.2-1.1-1.40.7-0.6-0.2
Body weight1.56.413.03.6-3.53.42.4-0.9-3.10.8-0.61.9
Weight adjusted by age0.10.41.00.7-0.50.51.0-0.1-0.50.6-0.70.3
Bone surface0.10.10.5-0.40.0-0.2-0.10.7-0.2-0.40.30.4
Bone volume0.00.10.3-0.20.2-0.3-0.1-0.0-0.6-0.0-0.10.3
Breakpoint value in progressive ratio session0.10.30.9-0.80.0-0.6-0.90.10.0-0.40.4-0.1
Number of licking bursts0.31.02.1-1.11.5-1.4-1.40.10.80.1-0.6-0.7
Context. condit. distance diff. score5.36.412.73.6-2.22.62.5-2.0-3.32.1-1.52.3
Locomotion velocity, session 11.11.24.3-0.2-0.40.91.32.11.0-1.00.91.1
Locomotion distance, session 12.53.27.1-2.72.4-2.3-1.81.72.1-0.70.4-0.2
Locomotion velocity, session 20.50.61.8-0.10.00.20.51.01.3-0.41.20.7
Locomotion distance, session 23.44.810.2-3.22.1-2.0-1.72.52.8-2.11.6-0.9
Locomotion velocity, session 31.92.13.61.9-0.80.80.7-1.4-1.51.9-1.71.7
Locomotion distance, session 32.02.36.2-0.31.5-1.6-1.7-1.6-0.61.9-2.50.6
Stereotopy head waving bouts, day 31.01.22.20.6-1.41.51.51.2-0.2-1.11.10.4
Stereotopy head waving duration, day 32.73.47.41.7-2.52.72.71.3-0.5-0.81.61.1
Locomotion velocity, session 70.30.40.80.6-0.30.40.5-0.5-0.90.8-0.30.7
Locomotion distance, session 70.30.30.9-0.1-0.10.60.90.6-0.8-0.50.10.7
Stereotopy head waving bouts, day 72.02.35.02.2-1.61.52.0-1.0-0.91.8-0.41.5
Stereotopy head waving duration, day 71.51.94.82.2-1.41.31.5-1.3-0.71.8-0.10.8
Locomotion velocity, session 81.61.94.01.4-1.92.01.71.0-0.4-0.30.81.6
Locomotion distance, session 80.50.81.51.2-0.41.01.2-0.6-1.20.7-0.20.9
Degree of sensitization distance3.53.89.41.0-2.22.73.11.5-0.9-1.92.30.2
Degree of sensitization stereotypy1.41.63.21.8-1.11.01.5-0.9-0.41.8-0.31.5
Conditioned locomotion0.60.71.71.0-0.91.31.10.2-0.50.00.31.1
Cocaine response after cond. corrected0.60.81.9-0.2-0.80.80.61.40.6-1.01.31.0
Cocaine response after cond. not corrected0.30.51.2-0.1-0.70.50.10.90.7-0.71.10.6
Cocaine response before conditioning0.70.81.9-0.00.7-1.0-1.3-1.4-0.00.9-0.8-0.8
Saline control response0.60.92.11.5-0.90.90.9-1.1-0.90.7-0.90.2
Bone: connectivity density0.20.31.00.5-0.60.60.70.3-1.0-0.30.20.2
Bone: cortical apparent density1.11.75.80.90.8-0.5-0.4-1.9-0.61.8-2.4-0.2
Bone: cortical area0.50.81.60.0-0.90.80.71.10.8-1.01.31.1
Bone: cortical porosity0.70.72.60.1-1.41.00.60.40.2-0.81.60.0
Bone: cortical porosity1.71.84.60.4-2.01.61.21.10.5-1.22.10.9
Bone: cortical thickness0.40.61.7-1.00.6-0.8-1.10.31.3-0.60.30.3
Bone: cortical thickness1.21.54.3-1.41.1-1.0-1.31.22.1-1.10.50.8
Bone: cortical tissue density1.01.55.50.90.7-0.5-0.4-1.8-0.61.7-2.3-0.1
Condit. Reinf. active minus inactive responses0.10.10.7-0.10.3-0.2-0.2-0.3-0.5-0.0-0.80.2
Condit. Reinf. active-inactive response ratio0.50.51.40.7-0.10.30.3-0.9-0.80.9-1.20.8
Condit. Reinf. active responses0.50.71.6-0.20.8-0.7-0.4-1.0-1.10.1-1.3-0.8
Condit. Reinf. inactive responses0.91.22.7-0.21.0-1.0-0.8-1.4-1.40.2-1.2-1.7
Incentive salience index mean0.20.20.7-0.30.5-0.4-0.4-0.3-0.5-0.1-0.8-0.2
Condit. Reinf. lever presses0.20.30.7-0.30.6-0.6-0.8-0.6-0.6-0.2-0.7-0.5
Condit. Reinf. active minus inactive responses0.60.92.9-1.00.3-0.1-0.41.71.1-1.30.80.3
Condit. Reinf. active-inactive response ratio0.50.72.5-0.4-0.40.60.31.60.6-1.30.90.6
Condit. Reinf. active responses0.50.72.6-0.9-0.10.0-0.21.61.0-1.10.80.6
Condit. Reinf. inactive responses0.30.41.0-1.00.4-0.7-0.60.60.9-0.10.20.7
Condit. Reinf. lever presses0.40.62.2-0.80.8-0.7-0.80.3-0.0-0.70.2-1.5
Condit. Reinf. lever reinforcers received0.60.82.7-0.7-0.20.30.11.60.9-1.31.10.3
Conditioned reinforcement - actives0.51.83.4-1.81.1-1.3-1.71.41.7-0.90.31.1
Conditioned reinforcement - inactives1.02.85.8-2.41.3-1.6-2.21.71.4-2.00.7-0.4
Conditioned locomotion1.21.73.9-1.20.1-0.2-1.02.01.5-1.91.70.5
Patch foraging indifference point 0 sec0.20.72.00.7-0.61.00.20.2-0.9-1.00.4-1.4
Patch foraging indifference point AUC0.71.63.6-1.91.6-1.2-1.41.31.5-0.9-0.30.3
Delay disc. indifference point, 0s delay0.20.21.0-0.1-0.50.3-0.20.30.5-0.71.0-0.3
Delay disc. indifference point, 16s delay2.12.98.6-2.91.9-2.1-1.21.32.2-1.00.7-0.6
Delay disc. indifference point, 2s delay4.44.910.6-3.12.4-2.9-2.71.03.3-0.31.10.0
Delay disc. indifference point, 24s delay0.40.72.5-1.20.3-0.50.21.60.8-0.50.00.8
Delay disc. indifference point, 4s delay1.41.53.6-1.91.2-1.3-1.11.21.6-0.80.9-0.1
Delay disc. indifference point, 8s delay1.01.64.5-2.11.6-1.7-1.50.70.7-0.80.0-0.8
Indifference point function ln k0.92.65.92.4-2.01.71.7-1.4-1.81.4-0.40.4
Indifference point function log k0.92.65.92.4-2.01.71.7-1.4-1.81.4-0.40.4
Patch foraging total patch changes 0 sec0.20.63.10.4-0.10.5-0.40.1-0.6-1.00.3-1.8
Patch foraging total patch changes 12 sec0.40.61.8-0.50.00.4-0.51.10.9-1.30.80.2
Patch foraging total patch changes 18 sec0.61.54.9-1.20.1-0.0-0.81.80.8-2.21.2-1.0
Patch foraging total patch changes 24 sec0.20.51.9-0.70.9-0.7-1.40.10.3-0.4-0.4-0.7
Patch foraging total patch changes 6 sec0.71.33.8-1.00.4-0.1-0.71.71.2-1.90.8-1.1
Patch foraging time to switch 0 sec0.20.63.4-0.5-0.20.20.40.51.0-0.61.8-0.2
Patch foraging water rate 0 sec0.20.72.31.1-0.71.00.3-0.0-1.5-0.4-0.8-0.3
Patch foraging water rate 12 sec0.10.61.90.9-0.00.1-0.2-1.0-0.70.6-0.8-1.4
Patch foraging water rate 18 sec0.10.30.60.6-0.60.70.70.2-0.3-0.3-0.5-0.8
Patch foraging water rate 24 sec1.52.24.82.2-1.92.01.7-0.6-1.80.3-0.4-0.2
Patch foraging water rate 6 sec0.81.23.40.8-0.1-0.1-0.3-1.6-1.60.9-1.9-0.9
Seeking ratio, delayed vs. immediate footshock0.30.41.2-0.61.1-0.9-0.6-0.30.10.4-0.1-0.8
Distance traveled before self-admin0.71.53.2-1.41.1-0.7-0.21.11.7-1.11.8-1.0
Distance traveled after self-admin0.91.65.0-0.5-0.70.70.81.90.3-2.21.7-0.8
Extensor digitorum longus weight0.51.93.6-1.21.9-1.9-1.7-0.51.60.10.0-1.8
Bone: elastic displacement0.30.41.40.8-0.70.91.20.30.00.10.2-0.2
Bone: elastic work2.02.64.60.8-1.92.12.11.70.7-1.22.11.1
Bone: endosteal estimation1.02.33.80.8-1.91.91.91.8-0.2-1.21.91.1
Bone: endosteal perimeter0.82.13.60.9-1.91.81.91.2-0.2-0.51.61.7
Epididymis fat weight1.36.412.43.5-3.43.22.2-1.3-2.91.3-0.52.7
Delta time in closed arm before/after self-admin0.60.61.5-0.70.5-0.2-1.20.51.1-0.80.00.9
Delta time in open arm before/after self-admin0.10.10.3-0.3-0.0-0.30.60.3-0.10.10.4-0.6
Diff in mean of infusions in LGA sessions0.10.30.8-0.1-0.50.20.50.7-0.7-0.00.00.9
Delay discount exponential model param2.02.77.62.7-1.92.21.7-1.2-1.80.8-0.60.4
Extinction: sum of active levers before priming0.81.32.8-1.70.3-1.0-0.81.11.6-0.31.11.3
Active lever presses in extinction session 60.10.10.3-0.4-0.0-0.20.10.40.30.20.50.4
Bone: final force1.01.63.7-0.2-1.01.00.81.90.9-1.71.91.0
Bone: final moment1.21.94.1-0.1-1.21.21.02.00.9-1.92.01.1
Food consumed during 24 hour testing period0.30.61.1-0.3-1.00.4-0.11.10.5-1.01.00.7
Glucose0.20.31.40.1-0.80.5-0.0-0.4-1.2-0.60.3-0.2
Heart weight2.33.88.91.8-2.92.73.01.2-1.1-0.71.41.0
Delay discount hyperbolic model param2.33.07.82.8-2.02.31.9-1.0-1.90.6-0.60.3
Intermittent access intake day 1-15 change0.00.20.80.2-0.0-0.3-0.7-0.6-0.30.2-0.6-0.9
Intermittent access intake escalation0.10.40.80.10.2-0.5-0.7-0.7-0.30.5-0.9-0.9
Intermittent access intake escalation 20.20.31.00.20.3-0.4-0.3-0.7-0.50.4-0.8-1.0
Intermitt. access day 1 inactive lever presses0.11.33.3-0.2-1.21.11.31.2-0.6-1.81.5-0.4
Intermitt. access day 15 inactive lever presses0.10.61.7-1.00.4-0.00.41.20.0-1.30.7-0.4
Intermitt. access escalation Index0.31.14.0-0.20.8-1.4-2.0-1.00.30.7-0.8-0.8
Intermittent access day 1 total infusions1.13.26.1-2.50.7-0.8-1.22.42.2-2.22.00.9
Intermittent access day 15 total infusions0.61.63.3-1.81.2-1.2-1.51.31.6-1.10.7-0.2
Intermittent access terminal intake (last 3 days)0.91.63.4-1.91.2-1.1-1.11.51.7-1.20.90.0
Intermittent access total infusions3.33.97.5-2.71.2-1.2-1.62.62.5-2.31.90.6
Intermittent access day 1 locomotion1.01.93.7-1.90.7-0.7-1.11.71.3-1.91.6-0.3
Intermittent access day 15 total locomotion0.20.82.4-1.20.2-0.1-0.51.30.4-1.61.00.4
Intermittent access total locomotion1.01.24.6-1.1-0.20.2-0.61.70.3-2.11.20.4
Intermittent access standard deviation0.42.47.2-1.1-1.00.90.72.00.7-2.72.4-0.3
Left kidney weight2.520.342.54.4-6.56.25.91.5-2.4-0.12.05.8
Right kidney weight3.725.658.55.1-7.67.26.61.3-3.6-0.41.95.7
Cocaine induced anxiety0.20.72.01.0-0.70.70.9-0.1-0.80.6-0.11.4
Post-drug Anxiety1.21.33.01.7-0.50.81.0-0.9-1.61.2-1.20.9
Baseline Anxiety0.20.41.1-0.21.1-0.6-0.7-0.20.30.1-0.8-0.7
Tail length0.31.95.81.6-1.21.31.2-1.0-2.40.3-1.4-0.9
Length with tail1.35.910.43.2-3.03.23.1-0.7-3.10.6-1.21.4
Length without tail1.26.514.52.8-3.83.83.50.8-2.2-0.50.81.9
Times rat made contact with spout0.40.51.6-0.40.2-0.7-1.0-0.2-0.7-0.1-1.30.6
Lifetime Intake3.64.58.4-2.91.0-1.1-1.52.82.7-2.52.31.1
Liver weight, left0.81.53.51.3-0.50.40.2-1.3-1.11.7-1.41.9
Liver weight, right3.76.511.43.4-2.41.71.2-3.0-3.42.8-2.41.7
Locomotor activity0.91.44.01.7-2.01.71.1-0.0-0.70.2-0.01.2
Locomotor testing distance0.10.20.60.4-0.0-0.1-0.7-0.6-0.20.2-0.8-0.1
Locomotor testing rearing0.10.51.90.9-1.00.90.6-0.0-0.20.10.21.4
Locomotion in novel chamber1.62.24.3-0.11.5-1.8-1.4-2.1-0.21.6-1.9-1.3
Locomotion in novel chamber post-restriction0.72.04.6-1.61.8-2.1-2.1-0.90.90.7-0.6-0.6
Fecal boli incidents, locomotor time 10.61.55.2-1.20.20.20.22.01.0-2.31.3-0.2
Change in fecal boli incidents, locomotor task1.61.74.21.7-0.90.90.4-0.7-0.81.6-1.82.1
Time >=10cm from walls, locomotor time 10.91.12.40.5-1.21.51.11.2-0.0-1.21.00.7
Bouts of movement, locomotor time 10.30.41.60.3-0.70.50.1-0.2-0.70.3-0.51.3
Total resting periods, locomotor time 10.10.20.7-0.0-0.50.50.20.4-0.3-0.20.10.8
Rest time, locomotor task time 10.30.50.70.1-0.80.80.70.9-0.5-0.60.80.6
Distance moved, locomotor task time 10.20.71.81.4-0.40.40.4-1.1-0.41.3-0.70.1
Vertical activity count, locomotor time 10.21.02.61.5-1.10.80.3-1.0-1.60.5-1.1-0.3
Time >=10cm from walls, locomotor time 20.10.40.90.5-1.01.00.90.6-0.3-0.40.4-0.2
Bouts of movement, locomotor time 20.41.34.4-0.81.2-1.5-2.1-1.00.81.1-0.3-0.0
Total resting periods, locomotor time 20.31.45.1-1.21.3-1.6-2.2-0.51.20.60.00.0
Rest time, locomotor task time 20.20.31.0-0.70.2-0.2-0.31.00.4-0.90.40.3
Distance moved, locomotor task time 20.60.71.31.2-0.90.71.1-0.9-1.01.0-0.40.1
Vertical activity count, locomotor time 20.30.62.00.9-1.40.80.5-0.5-1.30.1-0.4-0.1
Light reinforcement 10.00.20.5-0.20.3-0.0-0.20.50.7-0.50.6-0.5
Light reinforcement 20.20.31.20.6-0.20.20.1-1.1-0.21.1-0.10.5
Bone: marrow area1.02.54.10.8-2.02.01.91.8-0.3-1.31.91.2
Bone: maximum diameter1.73.35.71.0-2.42.32.21.80.3-1.12.02.1
Bone: maximum force1.32.76.2-0.3-1.31.21.02.51.1-2.12.31.5
Bone: maximum moment1.63.06.8-0.1-1.51.51.22.61.1-2.22.41.6
Mean time between licks in bursts0.21.03.7-0.71.4-1.0-0.60.21.90.20.7-0.9
Mean num. licks in bursts0.41.02.31.0-1.30.90.8-0.5-1.40.3-0.61.5
Cd content in liver0.70.83.70.9-0.40.3-0.4-0.1-0.10.7-1.31.9
Co content in liver0.60.82.1-0.90.7-0.6-1.01.01.4-1.00.4-0.3
Cu content in liver2.83.47.5-2.12.7-2.6-2.2-0.21.1-0.2-0.3-2.3
Fe content in liver2.93.68.11.8-2.82.82.81.1-0.3-1.11.60.6
K content in liver0.10.10.8-0.30.4-0.30.1-0.2-0.1-0.1-0.1-0.9
Mg content in liver0.10.10.4-0.40.3-0.20.20.2-0.2-0.50.4-0.7
Mn content in liver0.40.50.9-0.50.7-1.0-0.7-0.90.20.7-0.90.5
Na content in liver0.20.20.80.00.20.10.4-0.0-0.6-0.40.0-0.9
Rb content in liver0.50.61.7-0.70.50.0-0.11.31.1-1.01.0-0.2
Se content in liver0.81.02.50.40.5-0.9-0.7-1.50.01.5-1.6-0.3
Sr content in liver3.43.06.4-1.32.5-2.5-2.4-1.5-0.20.8-1.4-1.2
Zn content in liver0.20.20.60.20.1-0.2-0.2-0.3-0.70.5-0.8-0.0
Bone: minimum diameter0.40.81.6-0.1-1.00.80.61.10.1-1.01.31.0
Time in familiar zone, hab. session 10.30.31.3-0.50.3-0.1-0.11.10.7-0.40.30.8
Time in novel zone, hab. session 10.60.71.91.3-1.41.10.7-0.7-0.60.30.2-0.3
Total zone transitions, hab. session 11.52.14.6-0.92.1-2.0-1.4-1.00.31.2-2.1-1.0
Total locomotion distance, hab. session 10.91.34.60.11.2-1.0-0.6-1.3-0.81.5-2.1-0.6
Locomotion velocity, hab. session 10.81.23.3-0.41.5-1.2-0.6-0.9-0.81.1-1.8-0.8
Time in familiar zone, hab. session 20.81.02.10.40.9-0.8-0.8-1.4-0.71.5-1.3-0.5
Time in novel zone, hab. session 20.70.72.1-0.4-0.90.60.41.10.4-1.51.00.7
Total zone transitions, hab. session 20.81.02.1-1.51.0-0.7-0.41.51.2-1.20.3-0.3
Total locomotion distance, hab. session 21.01.32.4-1.40.8-0.4-0.11.61.4-1.51.0-1.0
Locomotion velocity, hab. session 21.21.62.8-1.61.0-0.5-0.21.71.4-1.71.1-1.2
Novel to familiar place preference ratio1.52.04.72.2-1.71.51.5-0.7-1.21.0-1.01.5
Novelty place preference2.12.76.12.5-1.91.61.6-1.0-1.41.3-1.31.7
Time in novel zone, NPP test2.63.27.12.7-2.01.71.6-1.1-1.71.5-1.51.9
Total zone transitions, NPP test1.01.54.1-1.42.0-1.7-1.10.21.00.2-1.2-0.8
Total locomotion distance, NPP test0.40.51.1-0.91.1-0.6-0.10.90.7-0.5-0.1-0.8
Locomotion velocity, NPP test0.70.92.4-1.31.6-1.1-0.60.71.0-0.4-0.1-1.1
Intraocular pressure0.20.41.00.7-0.70.90.60.2-0.20.40.11.0
Delta distance traveled before/after self-admin1.61.84.51.2-2.11.71.60.6-1.7-0.6-0.40.9
Delta ambulatory time before/after self-admin1.01.74.30.9-2.11.71.61.1-1.2-1.0-0.11.0
Parametrial fat weight0.92.14.31.8-0.70.60.2-2.1-2.11.5-2.0-0.3
Pavlov. Cond. lever latency0.20.20.90.5-0.40.70.90.2-0.20.1-0.00.5
Pavlov. Cond. magazine entry latency1.51.93.8-1.91.4-1.5-1.80.82.0-0.80.8-0.5
Pavlov. Cond. change in total contacts2.42.65.5-2.31.6-1.8-1.91.12.0-1.40.9-0.7
Pavlov. Cond. index score0.70.91.9-1.40.7-1.0-1.30.71.1-0.80.7-0.3
Pavlov. Cond. latency score0.40.61.4-1.00.5-0.8-1.20.40.8-0.60.5-0.4
Pavlov. Cond. lever contacts0.70.82.0-1.20.9-1.2-1.40.00.5-0.50.2-1.0
Pavlov. Cond. magazine entry number1.41.83.71.9-1.61.61.8-0.7-1.60.7-0.40.4
Pavlov. Cond. intertrial magazine entries0.10.20.40.0-0.00.10.40.2-0.6-0.7-0.6-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.92.2-1.40.9-1.1-1.50.51.0-0.60.5-0.3
Pavlov. Cond. response bias1.21.53.3-1.81.4-1.4-1.60.61.4-0.80.6-0.6
Pavlov. Cond. lever latency0.50.74.10.10.1-0.3-0.3-0.30.50.9-0.92.0
Pavlov. Cond. magazine entry latency1.01.53.4-1.50.8-0.7-0.61.11.0-1.80.9-1.8
Pavlov. Cond. change in total contacts1.43.47.60.1-1.71.91.82.40.3-2.82.5-1.1
Pavlov. Cond. index score0.61.03.7-0.70.10.20.40.90.2-1.61.0-1.9
Pavlov. Cond. latency score0.71.14.1-0.80.20.10.31.00.3-1.71.0-2.0
Pavlov. Cond. lever contacts0.50.74.50.0-0.10.40.40.2-0.5-0.90.7-2.1
Pavlov. Cond. magazine entry number0.40.51.80.5-0.1-0.1-0.3-0.7-0.41.3-0.61.3
Pavlov. Cond. intertrial magazine entries0.20.43.1-0.3-0.30.20.20.5-0.3-0.30.21.7
Pavlov. Cond. lever-magazine prob. diff.0.61.04.1-0.60.10.20.30.80.3-1.51.0-2.0
Pavlov. Cond. response bias0.71.03.7-0.60.10.20.30.90.2-1.61.3-1.9
Time in closed arm before self-admin0.71.38.0-0.90.6-0.70.20.10.3-1.00.8-2.8
Time in closed arm after self-admin0.10.10.70.1-0.50.5-0.00.1-0.3-0.80.0-0.1
Time in open arm before self-admin0.30.41.10.50.20.1-0.0-0.7-0.70.6-1.10.7
Time in open arm after self-admin0.50.51.40.30.6-0.7-0.5-0.9-0.61.2-0.9-0.4
Bone: periosteal estimation1.02.34.10.5-1.81.71.71.80.3-1.32.01.5
Bone: periosteal perimeter1.63.16.01.3-2.42.42.31.30.0-0.71.72.1
Bone: post-yield work0.71.35.0-1.00.1-0.2-0.22.21.1-1.31.21.0
Progressive ratio test 1 active lever presses1.83.26.0-2.50.7-0.9-1.22.42.4-2.11.80.7
Progressive ratio test 1 breakpoint1.72.95.7-2.40.8-0.9-1.22.32.3-1.91.70.7
Progressive ratio test 1 inactive lever presses1.64.28.0-2.80.7-1.0-0.92.52.4-2.82.7-0.5
Progressive ratio test 2 active lever presses1.82.56.1-2.50.9-1.3-1.81.81.7-1.70.81.1
Progressive ratio test 2 breakpoint2.22.86.8-2.61.0-1.5-1.91.81.9-1.60.91.1
Progressive ratio test 2 inactive lever presses0.82.56.8-2.61.5-2.1-2.20.91.2-1.20.3-0.3
Incentive Sensitization - Responses0.20.61.8-1.20.6-1.0-1.30.00.3-0.2-0.60.3
Incentive Sensitization - Breakpoint0.20.51.6-1.20.5-1.0-1.30.10.3-0.2-0.50.5
Sum of active levers in priming session hrs 5-60.10.10.2-0.0-0.1-0.10.2-0.1-0.50.30.1-0.3
Progressive ratio0.10.30.70.0-0.40.50.10.8-0.2-0.80.8-0.3
Food seeking constrained by brief footshock0.30.41.2-0.20.00.1-0.80.61.10.00.51.1
Seeking ratio, punishment vs. effort0.10.21.0-0.40.2-0.3-0.40.11.00.10.10.8
Retroperitoneal fat weight1.98.417.13.9-4.13.72.6-1.2-2.61.5-0.43.5
Reaction time number correct0.41.63.3-0.41.1-1.5-1.2-1.7-0.11.8-1.7-0.2
Reaction time mean minus median0.00.10.4-0.1-0.30.20.60.1-0.2-0.30.4-0.2
Reaction time mean minus median AUC0.10.40.90.6-0.80.60.8-0.5-1.00.20.00.3
Reaction time num false alarms0.20.41.10.7-0.60.40.3-0.6-0.20.4-0.4-1.1
Reaction time num false alarms AUC0.20.40.90.8-0.40.30.2-0.7-0.10.7-0.7-1.0
Reaction time trials correct on left0.41.63.3-0.41.1-1.5-1.2-1.7-0.11.8-1.7-0.2
Reaction time trials on left0.51.73.3-0.51.2-1.7-1.4-1.70.01.8-1.7-0.2
Reaction time mean0.20.41.70.4-0.50.71.30.1-0.5-0.30.5-0.3
Reaction time mean AUC0.10.21.10.3-0.40.51.10.0-0.6-0.20.3-0.0
Median of all reaction times0.20.31.50.4-0.30.61.20.1-0.2-0.30.6-0.2
Reaction time omissions0.81.33.2-1.71.2-1.8-1.60.21.4-0.00.2-0.1
Reaction time false alarm rate0.20.30.80.9-0.70.90.7-0.1-0.2-0.10.1-0.8
Reaction time premature initiation rate0.91.43.7-0.5-1.20.80.21.70.4-1.91.90.1
Reaction time premature initiations0.10.30.8-0.5-0.80.2-0.30.80.0-0.90.80.2
Std. dev. reaction times0.10.51.60.6-1.30.81.0-0.1-0.9-0.10.10.2
Reaction time trials completed0.51.73.3-0.51.2-1.7-1.4-1.70.01.8-1.7-0.2
Reaction time trials AUC0.41.32.9-0.20.8-1.3-1.1-1.6-0.11.7-1.6-0.0
Run reversals in cocaine runway, females0.50.50.90.9-0.10.50.9-0.8-0.50.9-0.9-0.4
Run reversals in cocaine runway, males0.70.83.80.3-0.10.81.40.80.00.2-0.41.9
Latency to leave start box in cocaine runway0.10.20.40.4-0.30.30.6-0.20.30.60.60.5
Latency to leave start box in cocaine runway, F0.30.41.7-0.30.3-0.10.10.61.3-0.11.10.1
Latency to leave start box in cocaine runway, M1.00.92.01.1-1.10.60.8-1.1-1.41.1-0.40.6
Std. dev. time between licks in bursts0.20.41.0-0.20.30.30.20.90.7-1.00.8-0.8
Total sessions with >9 infusions2.32.86.3-1.6-0.60.2-0.22.51.7-2.02.51.8
Short access day 1 total inactive lever presses2.44.813.9-1.0-0.91.71.83.50.8-3.73.00.0
Short access day 10 total inactive lever presses0.21.53.61.0-1.41.61.90.2-1.9-0.5-0.20.6
Short access day 1 total infusions0.81.64.3-1.2-0.40.30.51.90.6-2.12.00.4
Short access day 10 total infusions1.32.25.5-1.4-0.30.1-0.22.21.8-1.72.31.0
Short access total infusions2.63.67.9-2.20.0-0.3-0.42.82.1-2.42.71.4
Short access day 1 locomotion0.61.02.8-0.7-0.70.50.41.40.3-1.61.7-0.3
Short access day 10 total locomotion0.41.65.2-1.3-0.40.1-0.30.9-0.5-2.31.6-1.9
Short access total locomotion1.01.44.4-1.1-0.60.3-0.31.40.5-2.12.1-0.4
One hour access (0.3 mA shock)4.55.410.8-3.32.7-2.9-3.21.22.8-1.20.8-0.3
Compulsive drug intake0.50.82.2-0.81.0-1.2-0.9-0.2-0.10.6-1.50.7
One hour access (shock baseline)0.82.04.5-1.71.3-1.3-1.60.82.1-1.11.4-0.7
Social response proportion0.91.24.7-0.4-0.80.30.41.01.5-0.92.2-1.0
Social responses0.71.03.3-0.90.3-0.3-0.71.21.8-0.91.0-0.7
Social time1.82.94.8-2.21.6-1.5-2.01.02.0-1.61.2-1.8
Soleus weight0.10.41.1-0.90.1-0.4-0.90.6-0.0-1.0-0.7-0.0
Bone: stiffness1.01.94.20.1-1.51.41.11.80.4-1.92.10.7
Tibialis anterior weight1.44.910.1-2.63.0-3.0-3.20.02.2-0.8-0.1-2.0
Time to tail flick, vehicle, before self-admin0.10.10.3-0.4-0.50.00.30.5-0.5-0.50.10.1
Time to tail flick, vehicle, after self-admin0.30.61.50.6-0.90.80.8-0.1-1.2-0.2-0.7-0.9
Time to tail flick, test, before self-admin0.70.82.3-0.60.8-1.0-1.5-0.60.81.0-0.70.8
Time to tail flick, test, after self-admin0.20.20.4-0.20.4-0.6-0.2-0.60.00.3-0.6-0.5
Delta time to tail flick, vehicle, before/after SA0.30.40.8-0.0-0.30.70.50.70.4-0.90.8-0.6
Delta time to tail flick, test, before/after SA0.50.73.00.20.5-0.6-0.4-0.9-0.70.2-0.9-1.7
Tibia length0.51.33.70.4-1.41.21.11.40.5-0.60.61.9
Ambulatory time before self-admin0.30.81.5-1.01.1-0.9-0.60.51.2-0.60.9-1.0
Ambulatory time after self-admin0.50.72.7-0.3-0.40.40.51.30.2-1.60.7-1.0
Bone: tissue strength0.30.30.80.8-0.80.90.7-0.0-0.30.2-0.20.7
Total heroin consumption0.91.12.6-1.60.8-0.9-1.00.91.5-0.60.40.9
Bone: trabecular number0.20.40.80.6-0.10.00.2-0.7-0.80.9-0.70.7
Bone: trabecular spacing0.91.43.8-0.4-0.80.90.51.91.2-1.61.40.9
Bone: trabecular thickness0.50.72.50.20.5-0.5-0.3-1.6-1.30.9-0.7-0.4
Bone: trabecular tissue density0.50.85.60.40.4-0.2-0.5-0.8-0.30.0-0.4-2.4
Water consumed over 24 hours0.10.20.7-0.2-0.4-0.0-0.50.5-0.5-0.8-0.50.3
Number of responses in last shaping day3.84.99.1-3.01.0-1.5-1.42.12.7-2.72.9-1.4