Hub : Genes

Cbx1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_006247234.5 0.02 0.03 7.4e-03 0.01 0.01 0.01 0.01 9.2e-03 2.0e-02 2.1e-02 2.9e-02
2 Brain mRNA stability Cbx1 0.03 0.02 3.0e-03 0.02 0.02 0.02 0.02 2.8e-03 4.2e-03 2.7e-03 5.8e-03
3 pVTA gene expression Cbx1 0.04 0.03 2.7e-05 0.05 0.05 0.04 0.04 9.8e-05 9.6e-05 3.9e-04 4.8e-04
4 BLA gene expression Cbx1 0.07 0.05 8.7e-05 0.04 0.07 0.06 0.06 2.1e-03 9.4e-05 4.8e-04 5.5e-04
5 Adipose mRNA stability Cbx1 0.04 0.02 5.5e-07 0.05 0.05 0.05 0.04 3.9e-06 2.4e-06 7.2e-06 9.3e-06
6 NAcc gene expression Cbx1 0.06 0.04 5.7e-13 0.09 0.09 0.09 0.09 6.0e-14 2.3e-13 3.1e-13 1.3e-13
7 PL gene expression Cbx1 0.1 0.05 3.5e-15 0.16 0.14 0.14 0.15 1.0e-16 2.5e-15 1.3e-15 2.6e-16
8 IC gene expression Cbx1 0.07 0.05 4.8e-03 0.03 0.04 0.01 0.03 1.5e-02 1.3e-02 8.2e-02 2.9e-02
9 Brain gene expression Cbx1 0.18 0.1 0.0e+00 0.23 0.23 0.21 0.23 1.4e-21 8.1e-21 1.9e-19 2.0e-21
10 OFC intron excision ratio chr10_82281992_82285658 0.27 0.19 2.3e-03 0.07 0.09 0.11 0.11 8.1e-03 3.7e-03 1.4e-03 1.8e-03
11 OFC intron excision ratio chr10_82281814_82285658 0.26 0.2 3.4e-03 0.07 0.08 0.1 0.1 1.2e-02 6.0e-03 1.8e-03 2.5e-03
12 RMTg gene expression Cbx1 0.23 0.15 1.3e-04 0.13 0.14 0.15 0.14 2.6e-04 2.0e-04 1.0e-04 1.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.93.23.81.7-1.8-1.8-1.81.8-1.6-1.8-1.8-1.91.8-1.7-1.9
Area under the delay curve0.40.50.8-0.80.90.80.8-0.70.60.60.80.5-0.70.70.6
BMI with tail14.951.374.88.6-8.1-7.3-7.27.2-7.1-6.8-6.8-6.66.7-6.6-6.4
BMI without tail0.82.35.22.3-1.9-1.5-1.41.5-1.6-1.3-1.2-1.21.5-1.5-1.2
Body weight1.04.36.62.6-2.2-1.9-1.51.9-2.3-2.1-1.5-1.92.4-2.3-2.0
Weight adjusted by age0.50.81.2-0.51.00.90.9-0.90.70.90.91.1-1.01.00.9
Bone surface0.61.01.51.2-1.1-1.0-1.01.0-0.8-1.0-0.9-1.11.0-1.0-1.0
Bone volume1.73.13.61.9-1.8-1.8-1.71.7-1.6-1.8-1.7-1.91.7-1.7-1.7
Breakpoint value in progressive ratio session2.93.44.8-1.41.51.91.9-1.92.02.12.02.1-1.41.42.2
Number of licking bursts0.10.10.3-0.30.30.30.2-0.30.30.20.20.2-0.50.50.3
Context. condit. distance diff. score0.30.30.90.9-0.8-0.6-0.60.5-0.4-0.5-0.5-0.60.4-0.4-0.4
Locomotion velocity, session 10.30.30.50.1-0.4-0.6-0.50.6-0.7-0.6-0.7-0.50.7-0.7-0.6
Locomotion distance, session 12.73.44.8-2.12.21.92.0-1.91.71.71.91.6-1.71.71.5
Locomotion velocity, session 21.01.22.1-1.31.41.11.2-1.11.00.91.11.0-0.90.80.9
Locomotion distance, session 23.54.86.0-2.52.42.32.4-2.22.12.12.32.0-2.12.11.9
Locomotion velocity, session 30.00.00.00.20.10.10.2-0.10.00.20.20.1-0.00.00.2
Locomotion distance, session 33.03.23.8-1.51.81.91.9-1.91.81.81.91.7-1.81.81.8
Stereotopy head waving bouts, day 34.75.57.02.4-2.6-2.4-2.42.4-2.3-2.2-2.3-2.22.3-2.3-2.2
Stereotopy head waving duration, day 33.54.25.02.0-2.2-2.1-2.12.1-2.1-2.0-2.1-2.02.1-2.0-1.9
Locomotion velocity, session 71.51.71.9-0.81.11.31.3-1.31.31.31.41.4-1.41.41.4
Locomotion distance, session 75.46.87.2-2.52.52.72.7-2.72.72.62.72.6-2.62.62.6
Stereotopy head waving bouts, day 70.40.50.70.6-0.6-0.7-0.70.7-0.7-0.6-0.7-0.70.8-0.8-0.6
Stereotopy head waving duration, day 70.30.40.50.5-0.5-0.6-0.70.6-0.6-0.6-0.7-0.70.6-0.7-0.6
Locomotion velocity, session 80.10.10.80.9-0.5-0.3-0.20.2-0.0-0.3-0.1-0.3-0.10.1-0.2
Locomotion distance, session 80.71.11.4-0.91.11.11.2-1.11.00.91.10.8-1.11.10.9
Degree of sensitization distance0.00.00.1-0.0-0.10.10.1-0.20.20.20.20.4-0.20.20.3
Degree of sensitization stereotypy0.00.00.1-0.20.30.10.1-0.20.20.20.10.2-0.10.00.2
Conditioned locomotion1.11.31.51.2-1.2-1.1-1.01.1-1.1-1.2-1.0-1.21.2-1.2-1.1
Cocaine response after cond. corrected5.76.87.72.6-2.5-2.6-2.52.5-2.6-2.7-2.5-2.72.8-2.8-2.5
Cocaine response after cond. not corrected2.93.54.51.8-1.7-1.8-1.71.8-1.8-1.9-1.7-1.92.1-2.1-1.9
Cocaine response before conditioning2.83.43.9-2.02.01.91.9-1.91.91.81.91.8-1.71.71.7
Saline control response0.60.81.2-0.40.60.90.9-0.91.10.91.01.0-1.01.00.9
Bone: connectivity density0.20.30.50.5-0.6-0.6-0.60.5-0.3-0.6-0.6-0.70.6-0.6-0.6
Bone: cortical apparent density6.38.610.5-2.52.62.92.8-3.03.23.22.82.9-3.13.03.1
Bone: cortical area0.10.10.40.7-0.2-0.3-0.20.3-0.1-0.3-0.2-0.40.4-0.4-0.2
Bone: cortical porosity0.40.40.60.1-0.3-0.6-0.60.6-0.8-0.7-0.7-0.70.6-0.7-0.8
Bone: cortical porosity0.50.60.80.4-0.4-0.7-0.70.7-0.9-0.8-0.8-0.80.9-0.9-0.9
Bone: cortical thickness0.40.61.0-0.00.40.70.8-0.81.00.80.90.7-0.90.90.8
Bone: cortical thickness1.01.12.3-1.51.41.11.2-1.11.10.91.00.8-0.80.80.7
Bone: cortical tissue density6.89.311.2-2.62.83.02.9-3.13.43.33.03.0-3.23.13.2
Condit. Reinf. active minus inactive responses0.20.20.4-0.60.50.40.4-0.40.50.50.40.4-0.30.30.4
Condit. Reinf. active-inactive response ratio0.20.20.40.1-0.3-0.4-0.50.4-0.4-0.2-0.5-0.30.6-0.6-0.4
Condit. Reinf. active responses0.10.10.6-0.80.50.30.3-0.30.50.40.20.3-0.20.20.2
Condit. Reinf. inactive responses0.20.30.7-0.90.70.50.5-0.50.70.40.40.4-0.50.50.2
Incentive salience index mean0.40.51.2-1.10.90.70.6-0.70.70.80.60.7-0.60.50.6
Condit. Reinf. lever presses0.91.31.9-1.41.21.11.0-1.01.01.20.91.3-1.21.11.1
Condit. Reinf. active minus inactive responses0.00.10.2-0.1-0.0-0.2-0.20.2-0.5-0.2-0.2-0.10.2-0.2-0.3
Condit. Reinf. active-inactive response ratio0.30.40.70.1-0.5-0.6-0.60.6-0.8-0.5-0.7-0.50.6-0.6-0.7
Condit. Reinf. active responses0.00.00.1-0.40.30.10.1-0.1-0.00.10.10.3-0.20.10.1
Condit. Reinf. inactive responses0.40.50.8-0.50.70.70.6-0.70.80.70.70.9-0.90.90.8
Condit. Reinf. lever presses0.81.11.9-1.41.21.01.0-1.00.80.80.91.1-1.21.20.9
Condit. Reinf. lever reinforcers received0.10.20.3-0.50.50.40.4-0.40.30.40.40.6-0.50.50.4
Conditioned reinforcement - actives0.40.71.2-0.3-0.0-0.6-0.60.8-0.9-0.9-0.9-0.81.0-1.1-1.0
Conditioned reinforcement - inactives0.10.20.40.10.00.30.3-0.30.40.60.50.6-0.40.40.7
Conditioned locomotion3.64.76.60.6-1.2-2.0-2.02.2-2.5-2.3-2.3-2.32.5-2.6-2.5
Patch foraging indifference point 0 sec0.81.52.00.8-0.8-1.2-1.21.2-1.4-1.3-1.2-1.21.4-1.4-1.2
Patch foraging indifference point AUC0.20.30.5-0.40.50.50.4-0.50.50.60.40.4-0.70.70.4
Delay disc. indifference point, 0s delay1.51.62.3-0.71.11.31.2-1.31.41.21.31.4-1.51.51.3
Delay disc. indifference point, 16s delay0.30.40.90.3-0.4-0.6-0.50.6-0.6-0.6-0.6-0.90.6-0.5-0.7
Delay disc. indifference point, 2s delay0.30.30.6-0.30.60.60.6-0.60.20.40.70.7-0.70.80.6
Delay disc. indifference point, 24s delay0.30.30.9-0.80.90.60.6-0.60.60.50.50.2-0.10.10.4
Delay disc. indifference point, 4s delay4.04.25.2-1.82.02.22.3-2.22.12.02.32.0-1.91.92.0
Delay disc. indifference point, 8s delay0.10.10.4-0.60.60.30.3-0.30.20.20.2-0.0-0.10.10.1
Indifference point function ln k0.00.00.1-0.30.2-0.00.00.1-0.0-0.2-0.1-0.20.3-0.3-0.1
Indifference point function log k0.00.00.1-0.30.2-0.00.00.1-0.0-0.2-0.1-0.20.3-0.3-0.1
Patch foraging total patch changes 0 sec0.71.41.90.8-0.8-1.1-1.11.2-1.3-1.2-1.2-1.21.4-1.4-1.2
Patch foraging total patch changes 12 sec0.10.20.3-0.30.2-0.3-0.40.3-0.3-0.4-0.5-0.50.4-0.5-0.6
Patch foraging total patch changes 18 sec1.01.52.10.7-0.9-1.3-1.31.3-1.4-1.4-1.4-1.31.0-1.0-1.4
Patch foraging total patch changes 24 sec0.71.22.00.6-0.7-1.1-1.11.1-1.4-1.0-1.1-1.11.3-1.4-1.1
Patch foraging total patch changes 6 sec0.50.81.10.5-0.5-0.9-0.90.9-1.0-1.0-1.1-1.00.8-0.9-1.0
Patch foraging time to switch 0 sec0.10.10.3-0.0-0.1-0.3-0.30.3-0.3-0.5-0.4-0.40.3-0.3-0.5
Patch foraging water rate 0 sec0.61.21.91.4-1.2-1.0-1.01.0-1.1-1.0-0.9-1.11.2-1.2-0.9
Patch foraging water rate 12 sec0.10.20.60.40.10.40.5-0.40.40.50.60.5-0.30.40.8
Patch foraging water rate 18 sec0.50.71.7-0.10.50.80.9-0.80.81.01.01.2-0.60.61.3
Patch foraging water rate 24 sec0.50.71.31.1-0.9-0.8-0.80.8-0.8-0.7-0.7-0.70.9-0.9-0.6
Patch foraging water rate 6 sec0.10.10.20.1-0.00.20.2-0.30.30.50.30.4-0.30.30.5
Seeking ratio, delayed vs. immediate footshock0.50.61.81.3-1.2-0.8-0.80.7-0.4-0.6-0.7-0.80.5-0.5-0.4
Distance traveled before self-admin0.10.20.9-1.00.80.40.4-0.30.20.10.30.2-0.20.20.1
Distance traveled after self-admin0.70.91.5-0.00.0-0.8-0.60.8-1.1-1.2-0.9-1.01.2-1.2-1.2
Extensor digitorum longus weight0.10.42.11.4-0.8-0.5-0.30.5-0.6-0.6-0.2-0.40.5-0.5-0.2
Bone: elastic displacement0.30.30.40.3-0.5-0.6-0.60.6-0.6-0.5-0.6-0.60.6-0.6-0.6
Bone: elastic work0.00.00.1-0.0-0.0-0.10.00.1-0.1-0.1-0.1-0.30.2-0.1-0.2
Bone: endosteal estimation0.51.02.00.5-0.4-0.9-0.80.9-0.9-1.1-0.9-1.11.4-1.4-1.0
Bone: endosteal perimeter0.81.62.61.0-0.9-1.3-1.21.3-1.3-1.3-1.3-1.31.6-1.6-1.2
Epididymis fat weight0.20.61.00.7-0.7-0.8-0.70.8-1.0-0.8-0.8-0.70.8-0.8-0.8
Delta time in closed arm before/after self-admin0.10.10.30.6-0.3-0.1-0.00.0-0.0-0.10.00.00.1-0.10.3
Delta time in open arm before/after self-admin1.71.72.0-1.11.21.31.2-1.31.21.31.31.3-1.41.41.3
Diff in mean of infusions in LGA sessions0.50.71.7-0.40.40.70.7-0.81.11.00.81.3-0.40.41.0
Delay discount exponential model param0.60.71.00.9-1.0-0.9-1.00.9-0.7-0.8-0.9-0.60.7-0.7-0.7
Extinction: sum of active levers before priming0.50.51.0-1.01.00.80.9-0.80.50.60.80.6-0.30.20.6
Active lever presses in extinction session 60.20.20.30.3-0.3-0.4-0.40.4-0.4-0.5-0.4-0.40.5-0.5-0.4
Bone: final force0.30.40.60.5-0.3-0.6-0.50.6-0.5-0.7-0.6-0.80.7-0.8-0.7
Bone: final moment0.30.50.70.6-0.4-0.6-0.60.6-0.5-0.8-0.6-0.80.8-0.8-0.8
Food consumed during 24 hour testing period1.21.62.6-1.41.61.31.4-1.31.31.31.31.2-1.01.01.3
Glucose1.21.93.11.8-1.5-1.3-1.21.3-1.5-1.4-1.1-1.31.3-1.2-1.3
Heart weight1.62.43.71.9-1.8-1.5-1.51.5-1.7-1.3-1.4-1.61.5-1.4-1.3
Delay discount hyperbolic model param0.60.71.00.9-1.0-0.9-1.00.9-0.7-0.7-0.9-0.60.7-0.8-0.7
Intermittent access intake day 1-15 change0.40.91.7-0.1-0.4-0.9-0.91.0-1.2-1.1-1.1-1.10.9-1.0-1.3
Intermittent access intake escalation0.30.71.10.0-0.5-0.8-0.80.9-1.0-0.9-0.9-0.90.7-0.7-1.1
Intermittent access intake escalation 21.82.03.30.6-1.2-1.4-1.41.5-1.6-1.6-1.5-1.51.3-1.3-1.8
Intermitt. access day 1 inactive lever presses0.10.61.50.00.10.50.5-0.50.50.80.70.9-1.21.20.9
Intermitt. access day 15 inactive lever presses0.61.21.90.9-1.4-1.2-1.21.2-1.0-0.8-1.1-1.01.1-1.0-1.1
Intermitt. access escalation Index0.40.61.5-0.30.4-0.4-0.30.5-0.6-0.9-0.7-1.01.2-1.2-1.0
Intermittent access day 1 total infusions0.00.10.1-0.00.20.30.3-0.30.30.20.30.2-0.20.20.3
Intermittent access day 15 total infusions0.00.00.1-0.2-0.0-0.1-0.10.2-0.2-0.2-0.2-0.30.3-0.3-0.3
Intermittent access terminal intake (last 3 days)0.20.30.50.2-0.5-0.6-0.60.6-0.5-0.6-0.6-0.60.6-0.6-0.7
Intermittent access total infusions0.00.00.10.2-0.2-0.1-0.10.1-0.0-0.1-0.1-0.10.3-0.3-0.0
Intermittent access day 1 locomotion0.10.10.2-0.40.20.30.3-0.30.30.20.30.3-0.00.00.4
Intermittent access day 15 total locomotion0.20.30.5-0.20.0-0.4-0.40.5-0.5-0.6-0.6-0.70.7-0.7-0.7
Intermittent access total locomotion0.50.60.9-0.1-0.4-0.7-0.70.7-0.8-0.8-0.8-0.80.9-0.9-0.9
Intermittent access standard deviation1.02.23.00.7-1.5-1.4-1.41.5-1.4-1.4-1.4-1.51.7-1.7-1.6
Left kidney weight0.00.10.30.3-0.00.00.3-0.0-0.2-0.10.2-0.30.6-0.5-0.1
Right kidney weight0.31.52.21.4-1.3-1.1-1.01.2-1.3-1.1-0.9-1.21.5-1.4-1.1
Cocaine induced anxiety0.20.20.50.6-0.7-0.4-0.40.4-0.2-0.5-0.3-0.50.4-0.4-0.5
Post-drug Anxiety0.00.00.2-0.50.10.10.1-0.10.40.10.10.1-0.20.2-0.1
Baseline Anxiety0.80.91.5-1.21.00.90.8-0.90.81.00.81.0-1.01.00.8
Tail length14.155.183.4-9.18.87.88.1-7.66.97.07.56.8-6.26.26.5
Length with tail5.423.333.6-5.85.75.25.5-5.04.44.55.14.3-4.04.04.1
Length without tail0.10.40.91.0-0.7-0.5-0.40.6-0.7-0.8-0.4-0.70.5-0.5-0.7
Times rat made contact with spout0.00.00.1-0.30.40.20.2-0.20.30.30.20.10.0-0.10.2
Lifetime Intake0.00.00.10.1-0.2-0.0-0.00.0-0.1-0.0-0.0-0.00.2-0.20.1
Liver weight, left0.10.10.30.40.00.20.2-0.20.10.50.30.3-0.20.20.5
Liver weight, right0.10.10.4-0.40.60.40.5-0.40.30.20.40.00.0-0.00.1
Locomotor activity0.60.91.70.6-0.7-0.9-1.00.9-0.7-1.0-1.0-1.01.3-1.3-1.0
Locomotor testing distance1.32.33.31.1-1.3-1.5-1.61.5-1.2-1.6-1.6-1.51.8-1.8-1.5
Locomotor testing rearing0.00.00.1-0.0-0.2-0.1-0.20.10.10.0-0.10.00.2-0.20.1
Locomotion in novel chamber0.50.71.3-0.00.40.80.8-0.81.00.90.91.0-0.80.81.1
Locomotion in novel chamber post-restriction1.01.73.11.8-1.5-1.4-1.41.3-1.3-1.3-1.3-1.11.0-1.0-1.0
Fecal boli incidents, locomotor time 12.84.05.72.2-2.4-2.1-2.12.0-2.1-1.8-1.9-2.01.8-1.8-1.9
Change in fecal boli incidents, locomotor task2.42.32.7-1.31.51.61.6-1.61.61.51.61.6-1.41.41.5
Time >=10cm from walls, locomotor time 10.30.40.5-0.70.70.60.6-0.60.70.70.50.6-0.60.50.5
Bouts of movement, locomotor time 10.00.00.10.2-0.3-0.2-0.10.1-0.1-0.0-0.1-0.40.00.0-0.1
Total resting periods, locomotor time 10.10.20.50.6-0.7-0.4-0.40.4-0.4-0.2-0.3-0.60.0-0.0-0.3
Rest time, locomotor task time 10.30.40.70.5-0.7-0.7-0.60.7-0.8-0.5-0.6-0.80.4-0.4-0.7
Distance moved, locomotor task time 10.81.11.8-1.01.31.21.2-1.21.31.11.11.0-0.50.51.0
Vertical activity count, locomotor time 10.10.30.9-0.51.00.60.6-0.60.60.60.50.4-0.10.10.4
Time >=10cm from walls, locomotor time 20.50.81.1-0.70.80.90.9-0.90.81.00.91.0-0.80.81.0
Bouts of movement, locomotor time 20.00.10.10.3-0.2-0.3-0.30.3-0.2-0.1-0.3-0.30.2-0.2-0.2
Total resting periods, locomotor time 20.00.10.10.3-0.3-0.3-0.30.3-0.2-0.2-0.3-0.40.1-0.1-0.2
Rest time, locomotor task time 21.01.31.8-0.80.71.01.0-1.11.21.31.11.0-1.41.41.2
Distance moved, locomotor task time 20.10.10.2-0.20.50.40.5-0.40.20.20.40.40.2-0.10.4
Vertical activity count, locomotor time 20.10.10.40.10.3-0.00.10.1-0.4-0.1-0.1-0.20.6-0.6-0.1
Light reinforcement 10.20.40.70.3-0.7-0.7-0.80.8-0.6-0.7-0.8-0.60.6-0.6-0.7
Light reinforcement 20.00.10.1-0.20.0-0.2-0.20.2-0.2-0.3-0.2-0.20.3-0.3-0.2
Bone: marrow area0.30.81.70.4-0.3-0.8-0.70.8-0.8-1.0-0.8-1.01.3-1.3-0.8
Bone: maximum diameter0.81.52.41.0-0.8-1.2-1.21.2-1.1-1.3-1.2-1.31.5-1.5-1.2
Bone: maximum force0.50.91.40.9-0.6-0.9-0.80.9-0.8-1.1-0.9-1.21.1-1.1-1.1
Bone: maximum moment0.61.11.61.1-0.7-1.0-0.91.0-0.9-1.2-0.9-1.31.3-1.3-1.1
Mean time between licks in bursts0.10.21.11.0-0.7-0.4-0.40.4-0.3-0.3-0.3-0.40.3-0.3-0.2
Mean num. licks in bursts0.00.00.1-0.10.20.20.2-0.20.20.30.20.20.2-0.10.2
Cd content in liver0.00.00.10.2-0.1-0.0-0.10.00.00.1-0.00.20.0-0.00.2
Co content in liver0.00.00.10.0-0.20.10.2-0.10.00.10.20.1-0.00.10.1
Cu content in liver2.73.25.7-2.42.31.81.8-1.82.01.61.61.6-1.51.41.6
Fe content in liver0.50.60.9-0.81.00.80.9-0.80.90.80.90.8-0.40.40.8
K content in liver0.00.00.1-0.30.10.10.1-0.0-0.3-0.00.10.00.1-0.1-0.1
Mg content in liver2.62.73.1-1.81.71.71.7-1.71.51.61.71.6-1.51.51.6
Mn content in liver4.65.16.7-2.62.42.22.2-2.22.12.32.12.3-2.32.32.1
Na content in liver1.41.52.20.4-0.9-1.2-1.21.3-1.3-1.3-1.3-1.31.4-1.5-1.4
Rb content in liver0.40.50.7-0.60.60.60.5-0.60.70.70.50.7-0.90.80.7
Se content in liver0.40.50.70.8-0.8-0.8-0.80.7-0.6-0.7-0.8-0.60.6-0.6-0.7
Sr content in liver2.01.82.4-1.51.51.41.5-1.31.21.21.41.2-1.21.21.1
Zn content in liver0.10.10.20.3-0.3-0.3-0.30.3-0.5-0.2-0.3-0.10.3-0.3-0.2
Bone: minimum diameter0.10.20.60.3-0.0-0.3-0.20.3-0.2-0.4-0.2-0.50.7-0.7-0.4
Time in familiar zone, hab. session 10.60.61.2-0.40.30.60.5-0.71.10.90.60.7-1.11.10.8
Time in novel zone, hab. session 13.23.23.51.7-1.8-1.8-1.81.8-1.7-1.8-1.8-1.81.9-1.9-1.8
Total zone transitions, hab. session 16.69.210.1-2.72.93.13.1-3.13.13.13.22.9-3.13.12.9
Total locomotion distance, hab. session 12.94.15.0-2.01.92.02.0-2.02.12.02.01.9-2.22.21.8
Locomotion velocity, hab. session 13.85.45.8-2.32.42.42.4-2.42.22.32.42.3-2.42.42.2
Time in familiar zone, hab. session 20.40.41.01.0-1.0-0.7-0.80.6-0.5-0.3-0.6-0.30.1-0.2-0.3
Time in novel zone, hab. session 20.00.00.1-0.30.40.20.3-0.20.2-0.00.2-0.10.0-0.0-0.0
Total zone transitions, hab. session 21.92.53.8-1.91.91.61.6-1.61.51.51.51.4-1.41.41.3
Total locomotion distance, hab. session 20.10.10.3-0.60.40.20.2-0.20.20.20.10.1-0.30.20.0
Locomotion velocity, hab. session 20.10.10.6-0.70.60.40.4-0.30.30.30.30.2-0.30.30.1
Novel to familiar place preference ratio0.60.60.9-0.50.70.91.0-0.91.00.71.00.7-0.60.60.8
Novelty place preference0.70.81.2-0.60.80.91.0-1.01.10.81.00.8-0.70.80.9
Time in novel zone, NPP test0.50.61.0-0.40.60.80.9-0.81.00.70.90.7-0.70.70.8
Total zone transitions, NPP test4.05.88.0-2.72.82.52.5-2.42.22.22.42.1-2.42.42.0
Total locomotion distance, NPP test1.11.52.0-1.41.41.21.2-1.21.11.11.21.0-1.41.41.0
Locomotion velocity, NPP test1.72.43.2-1.81.81.61.6-1.51.41.41.51.3-1.71.71.2
Intraocular pressure1.11.63.4-1.81.81.31.4-1.31.21.01.20.8-1.01.00.9
Delta distance traveled before/after self-admin0.70.71.20.7-0.6-0.8-0.80.8-1.1-1.0-0.9-0.90.8-0.9-0.9
Delta ambulatory time before/after self-admin0.80.91.41.2-0.9-1.0-0.90.9-1.2-1.1-1.0-1.00.8-0.8-1.0
Parametrial fat weight0.10.30.70.7-0.4-0.5-0.40.4-0.5-0.5-0.5-0.60.8-0.8-0.4
Pavlov. Cond. lever latency1.51.92.61.0-1.2-1.3-1.21.3-1.3-1.5-1.3-1.61.6-1.5-1.6
Pavlov. Cond. magazine entry latency0.00.00.3-0.50.2-0.1-0.20.1-0.10.0-0.20.00.0-0.1-0.0
Pavlov. Cond. change in total contacts2.22.33.1-1.81.61.51.3-1.51.61.51.31.6-1.51.41.5
Pavlov. Cond. index score0.50.71.0-1.00.80.70.6-0.70.70.90.60.9-0.90.80.9
Pavlov. Cond. latency score0.60.81.1-0.90.90.80.7-0.80.81.00.71.0-1.01.01.0
Pavlov. Cond. lever contacts2.22.73.5-1.51.61.61.4-1.51.51.81.51.9-1.81.71.8
Pavlov. Cond. magazine entry number0.20.30.91.0-0.6-0.4-0.20.4-0.4-0.6-0.2-0.70.5-0.4-0.6
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.50.80.80.9-0.81.10.70.80.5-0.70.80.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.1-1.10.90.70.6-0.70.70.80.60.9-0.80.80.9
Pavlov. Cond. response bias0.70.81.4-1.20.90.80.6-0.80.81.00.61.1-0.90.91.0
Pavlov. Cond. lever latency0.50.71.0-0.81.00.90.9-0.90.91.00.90.7-0.60.60.9
Pavlov. Cond. magazine entry latency0.20.30.4-0.60.50.60.6-0.50.30.50.60.6-0.50.50.5
Pavlov. Cond. change in total contacts0.10.20.5-0.0-0.3-0.4-0.50.5-0.6-0.7-0.6-0.40.3-0.3-0.6
Pavlov. Cond. index score0.20.30.60.2-0.5-0.5-0.50.6-0.7-0.7-0.6-0.50.4-0.4-0.7
Pavlov. Cond. latency score0.10.10.3-0.0-0.3-0.3-0.20.3-0.5-0.5-0.3-0.30.3-0.2-0.5
Pavlov. Cond. lever contacts0.40.60.90.8-1.0-0.8-0.80.8-0.9-0.9-0.8-0.60.5-0.5-0.8
Pavlov. Cond. magazine entry number0.00.00.10.10.10.10.0-0.10.30.20.10.10.0-0.00.2
Pavlov. Cond. intertrial magazine entries1.82.73.4-1.31.51.61.6-1.71.81.71.71.6-1.71.71.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.3-0.5-0.5-0.50.6-0.8-0.7-0.6-0.50.4-0.4-0.7
Pavlov. Cond. response bias0.60.81.10.9-1.0-0.9-0.90.9-1.0-1.0-0.9-0.80.7-0.7-1.0
Time in closed arm before self-admin1.41.83.31.7-1.8-1.4-1.51.4-1.2-1.0-1.3-1.11.0-1.0-1.2
Time in closed arm after self-admin1.61.74.52.1-1.9-1.3-1.31.3-1.0-1.1-1.1-1.11.1-1.0-0.8
Time in open arm before self-admin0.10.10.5-0.40.70.30.4-0.30.3-0.10.20.0-0.30.30.2
Time in open arm after self-admin2.42.73.8-1.72.01.61.6-1.61.51.41.51.4-1.81.71.5
Bone: periosteal estimation0.51.11.90.9-0.6-1.0-0.91.0-0.8-1.1-1.0-1.21.4-1.4-1.0
Bone: periosteal perimeter0.81.32.11.5-1.2-1.2-1.11.1-1.0-1.1-1.0-1.11.3-1.3-0.9
Bone: post-yield work0.20.30.80.9-0.7-0.5-0.40.5-0.2-0.6-0.4-0.80.6-0.6-0.5
Progressive ratio test 1 active lever presses0.30.31.0-1.01.00.60.7-0.60.40.50.50.4-0.10.10.4
Progressive ratio test 1 breakpoint0.20.30.7-0.80.80.60.6-0.50.40.40.40.4-0.10.10.4
Progressive ratio test 1 inactive lever presses0.00.10.20.5-0.4-0.2-0.20.2-0.3-0.1-0.1-0.10.1-0.10.0
Progressive ratio test 2 active lever presses0.10.10.3-0.60.50.20.2-0.20.10.10.10.1-0.20.20.1
Progressive ratio test 2 breakpoint0.10.10.3-0.60.50.30.3-0.20.20.10.20.2-0.30.20.1
Progressive ratio test 2 inactive lever presses0.00.00.10.3-0.20.00.1-0.00.10.20.20.10.00.00.1
Incentive Sensitization - Responses0.00.00.1-0.20.1-0.1-0.10.1-0.3-0.1-0.10.1-0.10.1-0.1
Incentive Sensitization - Breakpoint0.00.00.2-0.1-0.0-0.2-0.20.3-0.4-0.2-0.2-0.10.1-0.1-0.3
Sum of active levers in priming session hrs 5-63.93.64.4-2.02.02.01.9-1.91.92.01.92.1-1.51.52.0
Progressive ratio0.60.91.90.4-0.20.60.5-0.60.70.90.91.3-1.31.41.4
Food seeking constrained by brief footshock0.50.61.20.0-0.2-0.8-0.80.9-0.8-0.8-0.9-0.90.9-0.9-1.1
Seeking ratio, punishment vs. effort0.50.71.6-1.00.8-0.3-0.20.4-0.3-0.5-0.7-1.11.2-1.3-1.1
Retroperitoneal fat weight0.52.02.61.0-1.2-1.4-1.31.4-1.6-1.4-1.4-1.51.6-1.6-1.5
Reaction time number correct0.20.30.70.3-0.20.30.3-0.40.70.60.50.7-0.70.80.8
Reaction time mean minus median0.30.62.4-1.61.50.70.7-0.70.60.60.40.4-0.50.40.1
Reaction time mean minus median AUC0.30.83.1-1.81.60.80.7-0.80.70.70.40.5-0.70.70.2
Reaction time num false alarms0.30.41.1-1.00.90.60.6-0.60.40.50.50.5-0.50.50.5
Reaction time num false alarms AUC0.30.51.4-1.21.00.70.7-0.60.40.60.60.6-0.50.50.5
Reaction time trials correct on left0.20.30.70.3-0.20.30.3-0.40.70.60.50.7-0.70.80.8
Reaction time trials on left0.20.30.70.3-0.20.40.3-0.40.70.60.50.7-0.70.80.8
Reaction time mean0.10.20.7-0.80.6-0.1-0.20.1-0.1-0.3-0.5-0.60.4-0.5-0.7
Reaction time mean AUC0.10.20.8-0.90.7-0.1-0.10.1-0.1-0.2-0.4-0.50.4-0.5-0.7
Median of all reaction times0.30.51.1-0.50.1-0.5-0.60.5-0.5-0.6-0.8-0.90.8-0.9-1.0
Reaction time omissions0.30.41.8-1.31.10.60.6-0.50.70.30.30.1-0.20.20.0
Reaction time false alarm rate0.10.21.1-1.10.80.30.3-0.2-0.10.00.10.00.1-0.1-0.1
Reaction time premature initiation rate0.30.50.9-0.90.90.70.7-0.60.50.50.60.6-0.70.70.6
Reaction time premature initiations0.61.01.3-0.90.91.01.0-1.01.00.91.01.1-1.11.11.1
Std. dev. reaction times0.20.41.8-1.31.30.50.5-0.40.40.30.10.0-0.20.2-0.2
Reaction time trials completed0.20.30.70.3-0.20.40.3-0.40.70.60.50.7-0.70.80.8
Reaction time trials AUC0.20.40.80.3-0.10.40.4-0.40.80.60.60.7-0.80.80.9
Run reversals in cocaine runway, females0.10.10.4-0.50.60.30.4-0.30.30.00.20.10.2-0.20.1
Run reversals in cocaine runway, males0.80.81.51.2-1.2-1.0-1.21.0-0.9-0.9-1.0-0.80.4-0.4-0.6
Latency to leave start box in cocaine runway3.03.46.72.6-2.4-1.9-1.91.9-1.8-1.7-1.7-1.51.5-1.4-1.5
Latency to leave start box in cocaine runway, F4.04.68.62.9-2.6-2.2-2.22.2-2.2-2.2-2.0-2.01.6-1.5-1.8
Latency to leave start box in cocaine runway, M0.40.40.80.6-0.8-0.6-0.60.6-0.4-0.3-0.5-0.30.9-0.9-0.5
Std. dev. time between licks in bursts1.21.61.90.8-1.0-1.2-1.21.3-1.3-1.4-1.3-1.31.3-1.4-1.4
Total sessions with >9 infusions0.10.10.40.1-0.1-0.3-0.20.3-0.6-0.3-0.3-0.30.4-0.4-0.2
Short access day 1 total inactive lever presses4.05.37.0-1.71.62.22.1-2.32.42.62.42.5-2.42.42.6
Short access day 10 total inactive lever presses0.10.31.10.9-1.0-0.6-0.70.6-0.3-0.2-0.5-0.2-0.30.3-0.2
Short access day 1 total infusions0.00.10.3-0.50.2-0.1-0.10.1-0.4-0.2-0.1-0.10.2-0.2-0.3
Short access day 10 total infusions0.50.61.20.3-0.7-0.7-0.70.8-1.1-0.6-0.7-0.71.1-1.1-0.8
Short access total infusions0.20.20.50.2-0.4-0.4-0.40.4-0.6-0.4-0.4-0.40.7-0.7-0.4
Short access day 1 locomotion1.31.62.60.7-1.3-1.2-1.21.3-1.6-1.2-1.2-1.21.3-1.3-1.4
Short access day 10 total locomotion1.22.23.10.3-1.1-1.4-1.51.6-1.8-1.6-1.6-1.41.6-1.6-1.7
Short access total locomotion1.21.52.30.7-1.1-1.2-1.21.3-1.5-1.2-1.2-1.21.3-1.3-1.3
One hour access (0.3 mA shock)0.40.40.6-0.70.80.70.7-0.70.70.70.60.7-0.50.50.6
Compulsive drug intake4.04.76.1-1.82.02.22.2-2.32.22.32.22.3-2.02.02.5
One hour access (shock baseline)1.42.22.71.1-1.4-1.5-1.51.5-1.5-1.5-1.5-1.51.6-1.6-1.6
Social response proportion0.91.02.7-1.61.41.11.2-1.00.90.81.00.6-0.70.70.6
Social responses0.00.00.2-0.40.30.20.2-0.20.20.10.2-0.00.1-0.10.0
Social time0.10.10.20.3-0.2-0.2-0.30.20.0-0.1-0.3-0.10.5-0.5-0.1
Soleus weight1.23.75.42.3-2.2-1.9-1.91.9-1.9-1.8-1.8-1.81.8-1.7-1.7
Bone: stiffness0.10.10.20.10.1-0.2-0.20.2-0.2-0.4-0.3-0.50.4-0.4-0.4
Tibialis anterior weight0.20.81.3-0.81.20.91.0-0.90.80.80.90.8-0.80.80.9
Time to tail flick, vehicle, before self-admin4.54.66.8-1.51.72.22.1-2.32.62.42.32.4-1.81.82.5
Time to tail flick, vehicle, after self-admin0.20.31.21.1-0.8-0.6-0.60.5-0.1-0.3-0.5-0.40.4-0.4-0.3
Time to tail flick, test, before self-admin0.10.20.60.7-0.5-0.4-0.40.4-0.0-0.2-0.3-0.30.3-0.3-0.3
Time to tail flick, test, after self-admin0.20.20.90.9-0.6-0.5-0.50.4-0.0-0.3-0.5-0.50.2-0.2-0.3
Delta time to tail flick, vehicle, before/after SA3.83.64.42.1-2.1-2.0-2.02.0-1.9-1.9-2.0-2.01.5-1.5-1.9
Delta time to tail flick, test, before/after SA0.30.30.5-0.70.60.60.6-0.60.50.50.50.6-0.60.60.5
Tibia length0.41.02.41.5-1.1-0.9-0.70.8-0.8-1.1-0.7-1.11.0-0.9-1.0
Ambulatory time before self-admin0.10.10.4-0.70.60.10.2-0.1-0.1-0.2-0.0-0.10.1-0.1-0.2
Ambulatory time after self-admin1.01.22.00.1-0.1-0.9-0.70.9-1.4-1.4-1.0-1.21.3-1.3-1.3
Bone: tissue strength0.10.10.70.8-0.6-0.3-0.30.3-0.2-0.2-0.2-0.10.2-0.1-0.1
Total heroin consumption1.21.42.0-1.01.01.21.1-1.21.31.41.11.3-1.01.01.4
Bone: trabecular number1.01.72.11.0-1.3-1.3-1.41.3-1.1-1.3-1.4-1.51.3-1.3-1.4
Bone: trabecular spacing0.10.10.3-0.20.30.30.2-0.20.00.30.30.6-0.40.30.5
Bone: trabecular thickness2.43.03.81.9-1.7-1.7-1.61.7-1.6-1.8-1.6-1.91.7-1.7-1.7
Bone: trabecular tissue density0.10.20.3-0.40.50.40.4-0.40.20.50.40.4-0.50.50.5
Water consumed over 24 hours0.10.20.30.00.40.40.3-0.40.50.50.40.4-0.50.40.6
Number of responses in last shaping day0.20.20.90.9-0.8-0.4-0.50.4-0.5-0.3-0.3-0.30.0-0.0-0.2