Hub : Genes

Card10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC isoform ratio NM_001130554.1 0.15 0.09 2.2e-03 0.04 0.03 0.04 0.03 7.3e-03 3.0e-02 1.1e-02 1.8e-02
2 Liver alternative TSS NM_001130554.1 0.03 0.02 1.8e-05 0.04 0.03 0.03 0.03 1.4e-05 2.1e-04 5.2e-04 1.8e-04
3 Liver alternative TSS XM_063263608.1 0.02 0.02 3.1e-03 0.02 0.01 0.02 0.01 1.7e-03 3.8e-02 5.5e-03 8.1e-03
4 Liver alternative TSS NM_001130554.1 0.03 0.02 2.1e-05 0.04 0.03 0.03 0.04 1.4e-05 1.3e-04 1.9e-04 5.0e-05
5 Liver alternative TSS XM_063263608.1 0.03 0.02 1.8e-03 0.02 0.01 0.02 0.02 1.1e-03 2.5e-02 3.1e-03 4.7e-03
6 Brain alternative TSS XM_063263608.1 0.02 0.02 6.8e-03 0.02 0.02 0.01 0.01 3.0e-03 4.3e-03 2.4e-02 1.3e-02
7 Brain alternative TSS XM_063263610.1 0.06 0.04 4.9e-05 0.06 0.06 0.05 0.06 2.8e-06 6.6e-06 8.1e-06 5.9e-06
8 Brain gene expression Card10 0.03 0.02 3.4e-03 0.03 0.01 0.01 0.01 1.9e-03 4.0e-02 1.3e-02 1.3e-02
9 Brain alternative TSS XM_063263610.1 0.03 0.02 3.1e-03 0.03 0.02 0.03 0.02 1.1e-03 4.2e-03 2.1e-03 4.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.40.71.10.31.0-1.01.0-1.0-0.90.6-0.60.6
Area under the delay curve0.30.41.51.2-0.30.3-0.30.30.30.7-0.70.7
BMI with tail1.65.48.9-0.52.7-2.72.7-2.7-3.01.9-1.91.9
BMI without tail0.51.43.2-0.11.5-1.51.5-1.5-1.80.3-0.30.3
Body weight1.14.68.4-1.72.5-2.52.5-2.5-2.91.2-1.21.2
Weight adjusted by age0.10.21.2-1.1-0.10.1-0.10.10.1-0.30.3-0.3
Bone surface0.20.30.5-0.1-0.70.7-0.70.70.7-0.30.3-0.3
Bone volume0.00.00.10.4-0.20.2-0.20.20.2-0.20.2-0.2
Breakpoint value in progressive ratio session0.30.40.60.40.6-0.60.6-0.6-0.80.6-0.60.6
Number of licking bursts1.11.82.11.1-1.31.3-1.31.31.3-1.41.4-1.4
Context. condit. distance diff. score0.50.62.5-1.60.7-0.70.7-0.7-0.80.4-0.40.4
Locomotion velocity, session 11.51.62.7-1.7-1.41.4-1.41.41.5-0.70.7-0.7
Locomotion distance, session 14.75.99.10.9-3.03.0-3.03.03.0-1.51.5-1.5
Locomotion velocity, session 20.40.51.4-1.2-0.30.3-0.30.30.20.9-0.90.9
Locomotion distance, session 22.63.65.71.1-2.42.4-2.42.42.4-0.90.9-0.9
Locomotion velocity, session 33.54.05.4-1.0-2.32.3-2.32.32.3-1.71.7-1.7
Locomotion distance, session 36.16.68.01.4-2.82.8-2.82.82.8-2.52.5-2.5
Stereotopy head waving bouts, day 30.60.71.5-1.20.8-0.80.8-0.8-0.80.7-0.70.7
Stereotopy head waving duration, day 32.73.27.7-2.81.7-1.71.7-1.7-1.71.5-1.51.5
Locomotion velocity, session 70.20.20.7-0.80.4-0.40.4-0.4-0.3-0.30.3-0.3
Locomotion distance, session 70.30.30.9-0.4-0.30.3-0.30.30.3-0.90.9-0.9
Stereotopy head waving bouts, day 71.01.27.0-2.60.5-0.50.5-0.5-0.50.8-0.80.8
Stereotopy head waving duration, day 71.82.16.3-2.51.1-1.11.1-1.1-1.11.5-1.51.5
Locomotion velocity, session 80.70.85.9-2.4-0.50.5-0.50.50.50.3-0.30.3
Locomotion distance, session 80.10.21.0-1.0-0.20.2-0.20.20.20.4-0.40.4
Degree of sensitization distance6.26.38.5-2.22.9-2.92.9-2.9-2.81.8-1.81.8
Degree of sensitization stereotypy0.91.06.8-2.60.1-0.10.1-0.1-0.10.9-0.90.9
Conditioned locomotion0.30.41.4-1.20.6-0.60.6-0.6-0.60.0-0.00.0
Cocaine response after cond. corrected0.60.81.3-1.10.7-0.70.7-0.7-0.71.0-1.01.0
Cocaine response after cond. not corrected1.01.21.6-0.71.1-1.11.1-1.1-0.91.2-1.21.2
Cocaine response before conditioning0.20.21.51.2-0.10.1-0.10.10.2-0.30.3-0.3
Saline control response0.40.60.8-0.1-0.80.8-0.80.80.9-0.70.7-0.7
Bone: connectivity density0.00.00.1-0.30.2-0.20.2-0.2-0.1-0.20.2-0.2
Bone: cortical apparent density1.52.03.91.2-1.01.0-1.01.01.1-2.02.0-2.0
Bone: cortical area0.40.70.8-0.70.9-0.90.9-0.9-0.90.7-0.70.7
Bone: cortical porosity1.21.32.1-0.81.0-1.01.0-1.0-1.01.4-1.41.4
Bone: cortical porosity1.21.32.8-1.70.7-0.70.7-0.7-0.71.4-1.41.4
Bone: cortical thickness0.20.32.31.50.0-0.00.0-0.0-0.0-0.10.1-0.1
Bone: cortical thickness0.20.21.71.3-0.20.2-0.20.20.2-0.10.1-0.1
Bone: cortical tissue density1.62.14.01.1-1.01.0-1.01.01.2-2.02.0-2.0
Condit. Reinf. active minus inactive responses1.51.72.60.8-1.21.2-1.21.21.2-1.61.6-1.6
Condit. Reinf. active-inactive response ratio2.02.22.90.2-1.51.5-1.51.51.5-1.71.7-1.7
Condit. Reinf. active responses1.11.32.91.7-0.60.6-0.60.60.8-1.51.5-1.5
Condit. Reinf. inactive responses0.50.74.12.00.4-0.40.4-0.4-0.3-0.60.6-0.6
Incentive salience index mean1.31.63.21.2-0.80.8-0.80.80.9-1.81.8-1.8
Condit. Reinf. lever presses0.71.02.31.5-0.00.0-0.00.00.1-1.51.5-1.5
Condit. Reinf. active minus inactive responses0.10.10.2-0.0-0.20.2-0.20.20.20.4-0.40.4
Condit. Reinf. active-inactive response ratio0.20.20.4-0.50.3-0.30.3-0.3-0.30.6-0.60.6
Condit. Reinf. active responses0.20.30.3-0.4-0.60.6-0.60.60.50.6-0.60.6
Condit. Reinf. inactive responses1.11.52.40.1-1.51.5-1.51.51.5-0.60.6-0.6
Condit. Reinf. lever presses0.10.10.50.70.1-0.10.1-0.1-0.10.2-0.20.2
Condit. Reinf. lever reinforcers received0.20.20.6-0.6-0.20.2-0.20.20.10.7-0.70.7
Conditioned reinforcement - actives1.72.94.71.4-2.22.2-2.22.22.2-0.40.4-0.4
Conditioned reinforcement - inactives0.81.25.32.3-0.90.9-0.90.90.9-0.60.6-0.6
Conditioned locomotion0.60.82.00.4-0.40.4-0.40.40.41.4-1.41.4
Patch foraging indifference point 0 sec0.40.61.30.3-0.60.6-0.60.60.5-1.11.1-1.1
Patch foraging indifference point AUC5.07.29.31.1-3.13.1-3.13.12.9-2.42.4-2.4
Delay disc. indifference point, 0s delay3.33.64.80.32.2-2.22.2-2.2-2.01.7-1.71.7
Delay disc. indifference point, 16s delay0.40.41.11.1-0.60.6-0.60.60.60.5-0.50.5
Delay disc. indifference point, 2s delay2.02.35.91.50.3-0.30.3-0.3-0.32.4-2.42.4
Delay disc. indifference point, 24s delay5.36.07.2-0.1-2.72.7-2.72.72.7-2.52.5-2.5
Delay disc. indifference point, 4s delay0.80.92.20.30.5-0.50.5-0.5-0.51.5-1.51.5
Delay disc. indifference point, 8s delay0.50.62.81.7-0.60.6-0.60.60.6-0.60.6-0.6
Indifference point function ln k1.52.73.4-1.41.8-1.81.8-1.8-1.81.4-1.41.4
Indifference point function log k1.52.73.4-1.41.8-1.81.8-1.8-1.81.4-1.41.4
Patch foraging total patch changes 0 sec0.40.81.30.8-0.80.8-0.80.80.6-1.11.1-1.1
Patch foraging total patch changes 12 sec2.02.63.60.2-1.91.9-1.91.91.8-1.41.4-1.4
Patch foraging total patch changes 18 sec1.42.22.50.7-1.51.5-1.51.51.4-1.61.6-1.6
Patch foraging total patch changes 24 sec2.13.74.81.6-1.81.8-1.81.81.9-2.22.2-2.2
Patch foraging total patch changes 6 sec1.21.82.50.8-1.61.6-1.61.61.1-1.21.2-1.2
Patch foraging time to switch 0 sec3.57.29.4-1.02.6-2.62.6-2.6-2.73.1-3.13.1
Patch foraging water rate 0 sec1.22.55.70.4-1.01.0-1.01.01.1-2.42.4-2.4
Patch foraging water rate 12 sec0.30.61.60.6-0.10.1-0.10.10.3-1.31.3-1.3
Patch foraging water rate 18 sec2.64.06.9-0.2-1.71.7-1.71.71.8-2.62.6-2.6
Patch foraging water rate 24 sec0.30.41.6-1.30.1-0.10.1-0.1-0.1-0.70.7-0.7
Patch foraging water rate 6 sec1.42.04.71.4-0.60.6-0.60.60.9-2.22.2-2.2
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.1-0.10.1-0.10.10.10.6-0.60.6
Distance traveled before self-admin1.21.52.90.11.0-1.01.0-1.0-1.01.7-1.71.7
Distance traveled after self-admin0.20.30.5-0.4-0.50.5-0.50.50.1-0.70.7-0.7
Extensor digitorum longus weight1.24.95.21.52.3-2.32.3-2.3-2.32.3-2.32.3
Bone: elastic displacement0.70.82.0-1.40.9-0.90.9-0.9-0.90.7-0.70.7
Bone: elastic work3.24.17.0-2.61.9-1.91.9-1.9-2.02.0-2.02.0
Bone: endosteal estimation0.51.06.8-2.60.4-0.40.4-0.4-0.40.8-0.80.8
Bone: endosteal perimeter0.81.77.0-2.61.0-1.01.0-1.0-0.91.1-1.11.1
Epididymis fat weight0.72.33.6-1.71.5-1.51.5-1.5-1.91.3-1.31.3
Delta time in closed arm before/after self-admin0.40.41.11.1-0.70.7-0.70.70.50.2-0.20.2
Delta time in open arm before/after self-admin0.10.10.3-0.50.2-0.20.2-0.2-0.00.4-0.40.4
Diff in mean of infusions in LGA sessions0.60.70.9-0.4-0.90.9-0.90.90.7-0.90.9-0.9
Delay discount exponential model param0.30.41.4-1.20.4-0.40.4-0.4-0.5-0.50.5-0.5
Extinction: sum of active levers before priming0.30.30.9-0.3-0.30.3-0.30.30.20.9-0.90.9
Active lever presses in extinction session 60.10.10.3-0.50.2-0.20.2-0.2-0.20.5-0.50.5
Bone: final force0.71.01.7-1.30.9-0.90.9-0.9-1.01.0-1.01.0
Bone: final moment0.71.12.2-1.51.0-1.01.0-1.0-1.01.0-1.01.0
Food consumed during 24 hour testing period0.00.10.1-0.2-0.30.3-0.30.30.30.2-0.20.2
Glucose0.60.91.60.91.2-1.21.2-1.2-1.30.1-0.10.1
Heart weight1.11.78.3-2.91.1-1.11.1-1.1-1.20.5-0.50.5
Delay discount hyperbolic model param0.50.51.8-1.30.3-0.30.3-0.3-0.3-0.90.9-0.9
Intermittent access intake day 1-15 change0.20.30.60.8-0.70.7-0.70.70.6-0.30.3-0.3
Intermittent access intake escalation0.30.60.80.9-0.90.9-0.90.90.8-0.60.6-0.6
Intermittent access intake escalation 20.30.30.90.9-0.40.4-0.40.40.4-0.70.7-0.7
Intermitt. access day 1 inactive lever presses0.10.30.4-0.70.6-0.60.6-0.6-0.6-0.30.3-0.3
Intermitt. access day 15 inactive lever presses0.10.10.30.4-0.30.3-0.30.30.0-0.50.5-0.5
Intermitt. access escalation Index0.30.51.91.4-0.60.6-0.60.60.6-0.50.5-0.5
Intermittent access day 1 total infusions1.62.64.80.2-2.22.2-2.22.22.00.4-0.40.4
Intermittent access day 15 total infusions1.72.54.50.9-2.12.1-2.12.12.0-0.20.2-0.2
Intermittent access terminal intake (last 3 days)2.22.95.20.5-2.32.3-2.32.32.2-0.20.2-0.2
Intermittent access total infusions1.82.23.80.6-1.91.9-1.91.91.80.5-0.50.5
Intermittent access day 1 locomotion0.40.50.90.7-0.90.9-0.90.90.60.3-0.30.3
Intermittent access day 15 total locomotion0.20.40.70.6-0.90.9-0.90.90.7-0.10.1-0.1
Intermittent access total locomotion0.10.10.60.8-0.40.4-0.40.40.2-0.00.0-0.0
Intermittent access standard deviation0.30.61.0-0.10.6-0.60.6-0.6-0.81.0-1.01.0
Left kidney weight1.67.535.7-6.01.6-1.61.6-1.6-1.92.5-2.52.5
Right kidney weight2.411.035.5-6.02.7-2.72.7-2.7-3.12.8-2.82.8
Cocaine induced anxiety0.81.21.5-0.51.1-1.11.1-1.1-1.11.2-1.21.2
Post-drug Anxiety2.62.84.6-0.42.1-2.12.1-2.1-2.21.0-1.01.0
Baseline Anxiety0.20.20.50.50.2-0.20.2-0.2-0.2-0.70.7-0.7
Tail length0.10.51.40.20.0-0.00.0-0.0-0.1-1.21.2-1.2
Length with tail0.10.52.6-1.60.5-0.50.5-0.5-0.8-0.40.4-0.4
Length without tail0.51.88.7-2.91.0-1.01.0-1.0-1.10.8-0.80.8
Times rat made contact with spout7.68.712.71.9-2.72.7-2.72.72.7-3.63.6-3.6
Lifetime Intake1.61.93.30.6-1.81.8-1.81.81.70.6-0.60.6
Liver weight, left0.30.40.7-0.1-0.80.8-0.80.80.8-0.30.3-0.3
Liver weight, right0.20.30.9-1.0-0.40.4-0.40.40.3-0.60.6-0.6
Locomotor activity0.10.21.0-1.00.3-0.30.3-0.3-0.40.3-0.30.3
Locomotor testing distance0.20.41.11.1-0.20.2-0.20.20.3-0.70.7-0.7
Locomotor testing rearing0.10.20.3-0.5-0.50.5-0.50.50.5-0.20.2-0.2
Locomotion in novel chamber0.30.43.01.7-0.10.1-0.10.1-0.0-0.20.2-0.2
Locomotion in novel chamber post-restriction0.30.52.71.6-0.50.5-0.50.50.6-0.20.2-0.2
Fecal boli incidents, locomotor time 11.01.41.8-0.4-1.11.1-1.11.11.3-1.31.3-1.3
Change in fecal boli incidents, locomotor task2.12.12.8-0.3-1.51.5-1.51.51.3-1.71.7-1.7
Time >=10cm from walls, locomotor time 10.40.41.3-1.10.3-0.30.3-0.3-0.40.8-0.80.8
Bouts of movement, locomotor time 10.20.20.3-0.1-0.40.4-0.40.40.4-0.50.5-0.5
Total resting periods, locomotor time 10.00.00.1-0.30.1-0.10.1-0.1-0.1-0.20.2-0.2
Rest time, locomotor task time 10.10.10.3-0.30.2-0.20.2-0.2-0.2-0.50.5-0.5
Distance moved, locomotor task time 10.00.10.4-0.70.1-0.10.1-0.10.10.2-0.20.2
Vertical activity count, locomotor time 10.20.50.60.60.7-0.70.7-0.7-0.5-0.60.6-0.6
Time >=10cm from walls, locomotor time 20.30.51.1-1.0-0.20.2-0.20.20.0-1.01.0-1.0
Bouts of movement, locomotor time 20.50.71.51.20.5-0.50.5-0.5-0.71.1-1.11.1
Total resting periods, locomotor time 20.50.81.71.20.3-0.30.3-0.3-0.61.3-1.31.3
Rest time, locomotor task time 20.00.00.00.10.1-0.10.1-0.10.0-0.10.1-0.1
Distance moved, locomotor task time 20.20.20.8-0.90.4-0.40.4-0.4-0.1-0.30.3-0.3
Vertical activity count, locomotor time 20.40.50.9-0.00.6-0.60.6-0.6-0.4-1.01.0-1.0
Light reinforcement 10.00.00.1-0.2-0.10.1-0.10.10.4-0.10.1-0.1
Light reinforcement 20.40.61.0-0.40.7-0.70.7-0.7-0.51.0-1.01.0
Bone: marrow area0.51.17.3-2.70.3-0.30.3-0.3-0.30.7-0.70.7
Bone: maximum diameter1.01.96.6-2.61.1-1.11.1-1.1-1.11.2-1.21.2
Bone: maximum force0.61.02.0-1.40.8-0.80.8-0.8-0.91.0-1.01.0
Bone: maximum moment0.61.12.7-1.60.9-0.90.9-0.9-0.91.1-1.11.1
Mean time between licks in bursts0.92.13.5-0.61.2-1.21.2-1.2-1.31.9-1.91.9
Mean num. licks in bursts0.60.91.40.2-0.90.9-0.90.90.9-1.21.2-1.2
Cd content in liver0.80.91.40.2-1.21.2-1.21.21.2-0.60.6-0.6
Co content in liver0.10.10.90.90.1-0.10.1-0.10.1-0.20.2-0.2
Cu content in liver1.11.34.82.2-0.80.8-0.80.80.6-1.21.2-1.2
Fe content in liver2.73.38.1-2.91.6-1.61.6-1.6-1.71.6-1.61.6
K content in liver0.20.20.30.3-0.30.3-0.30.30.3-0.50.5-0.5
Mg content in liver0.40.40.60.2-0.60.6-0.60.60.5-0.80.8-0.8
Mn content in liver0.70.71.00.9-1.01.0-1.01.01.0-0.60.6-0.6
Na content in liver0.10.10.30.20.5-0.50.5-0.5-0.6-0.10.1-0.1
Rb content in liver0.00.00.1-0.1-0.10.1-0.10.10.2-0.20.2-0.2
Se content in liver0.20.20.50.7-0.50.5-0.50.50.5-0.20.2-0.2
Sr content in liver1.00.87.22.70.1-0.10.1-0.1-0.1-0.30.3-0.3
Zn content in liver1.51.62.00.6-1.41.4-1.41.41.3-1.21.2-1.2
Bone: minimum diameter0.10.10.6-0.70.1-0.10.1-0.1-0.10.5-0.50.5
Time in familiar zone, hab. session 10.10.10.5-0.7-0.20.2-0.20.20.1-0.30.3-0.3
Time in novel zone, hab. session 10.20.20.3-0.50.4-0.40.4-0.4-0.40.6-0.60.6
Total zone transitions, hab. session 12.13.03.81.7-1.91.9-1.91.91.9-1.31.3-1.3
Total locomotion distance, hab. session 11.92.73.61.2-1.81.8-1.81.81.9-1.51.5-1.5
Locomotion velocity, hab. session 11.82.63.31.4-1.71.7-1.71.71.8-1.51.5-1.5
Time in familiar zone, hab. session 20.30.30.40.4-0.50.5-0.50.50.5-0.70.7-0.7
Time in novel zone, hab. session 20.10.10.20.20.1-0.10.1-0.1-0.10.4-0.40.4
Total zone transitions, hab. session 23.24.15.10.7-2.22.2-2.22.22.3-1.91.9-1.9
Total locomotion distance, hab. session 20.81.11.70.1-1.31.3-1.31.31.3-0.70.7-0.7
Locomotion velocity, hab. session 20.81.11.60.2-1.31.3-1.31.31.3-0.90.9-0.9
Novel to familiar place preference ratio0.20.21.1-1.1-0.40.4-0.40.40.30.0-0.00.0
Novelty place preference0.20.21.0-1.0-0.50.5-0.50.50.5-0.20.2-0.2
Time in novel zone, NPP test0.30.31.0-1.0-0.50.5-0.50.50.6-0.20.2-0.2
Total zone transitions, NPP test3.75.36.91.5-2.62.6-2.62.62.6-2.02.0-2.0
Total locomotion distance, NPP test1.72.33.50.1-1.81.8-1.81.81.9-1.21.2-1.2
Locomotion velocity, NPP test1.62.23.30.4-1.71.7-1.71.71.8-1.21.2-1.2
Intraocular pressure0.20.21.0-1.0-0.50.5-0.50.50.40.1-0.10.1
Delta distance traveled before/after self-admin3.73.96.1-0.9-1.91.9-1.91.91.6-2.52.5-2.5
Delta ambulatory time before/after self-admin3.84.76.3-1.2-2.12.1-2.12.11.9-2.52.5-2.5
Parametrial fat weight0.40.91.60.41.2-1.21.2-1.2-1.3-0.50.5-0.5
Pavlov. Cond. lever latency0.00.00.1-0.4-0.10.1-0.10.10.10.2-0.20.2
Pavlov. Cond. magazine entry latency0.20.20.40.60.4-0.40.4-0.4-0.40.6-0.60.6
Pavlov. Cond. change in total contacts0.60.71.21.1-0.90.9-0.90.90.9-0.50.5-0.5
Pavlov. Cond. index score0.00.00.20.4-0.00.0-0.00.00.0-0.20.2-0.2
Pavlov. Cond. latency score0.00.00.10.40.2-0.20.2-0.2-0.2-0.00.0-0.0
Pavlov. Cond. lever contacts0.10.10.60.80.2-0.20.2-0.2-0.2-0.40.4-0.4
Pavlov. Cond. magazine entry number0.20.31.0-1.00.5-0.50.5-0.5-0.50.4-0.40.4
Pavlov. Cond. intertrial magazine entries0.91.12.20.8-0.70.7-0.70.70.8-1.51.5-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.6-0.10.1-0.10.10.2-0.30.3-0.3
Pavlov. Cond. response bias0.10.10.70.80.0-0.00.0-0.0-0.0-0.20.2-0.2
Pavlov. Cond. lever latency0.60.91.30.4-1.21.2-1.21.21.2-0.50.5-0.5
Pavlov. Cond. magazine entry latency0.20.21.11.00.4-0.40.4-0.4-0.40.1-0.10.1
Pavlov. Cond. change in total contacts1.93.14.4-2.02.0-2.02.0-2.0-2.11.2-1.21.2
Pavlov. Cond. index score0.30.40.8-0.00.8-0.80.8-0.8-0.90.2-0.20.2
Pavlov. Cond. latency score0.30.40.70.10.8-0.80.8-0.8-0.80.1-0.10.1
Pavlov. Cond. lever contacts0.40.50.9-0.30.9-0.90.9-0.9-0.90.3-0.30.3
Pavlov. Cond. magazine entry number0.20.30.5-0.1-0.70.7-0.70.70.7-0.30.3-0.3
Pavlov. Cond. intertrial magazine entries0.30.40.70.1-0.50.5-0.50.50.5-0.90.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.3-0.11.1-1.11.1-1.1-1.10.5-0.50.5
Pavlov. Cond. response bias0.60.81.2-0.31.0-1.01.0-1.0-1.10.6-0.60.6
Time in closed arm before self-admin1.41.83.30.91.8-1.81.8-1.8-1.40.4-0.40.4
Time in closed arm after self-admin0.20.21.01.00.1-0.10.1-0.1-0.2-0.50.5-0.5
Time in open arm before self-admin0.80.81.3-0.1-0.90.9-0.90.90.7-1.11.1-1.1
Time in open arm after self-admin0.00.00.00.1-0.00.0-0.00.00.2-0.20.2-0.2
Bone: periosteal estimation0.51.14.8-2.20.7-0.70.7-0.7-0.70.9-0.90.9
Bone: periosteal perimeter0.61.17.1-2.70.6-0.60.6-0.6-0.60.6-0.60.6
Bone: post-yield work0.20.30.5-0.4-0.70.7-0.70.70.7-0.30.3-0.3
Progressive ratio test 1 active lever presses1.31.62.70.2-1.71.7-1.71.71.50.5-0.50.5
Progressive ratio test 1 breakpoint1.41.73.10.2-1.81.8-1.81.81.60.3-0.30.3
Progressive ratio test 1 inactive lever presses1.11.63.50.30.8-0.80.8-0.8-0.91.9-1.91.9
Progressive ratio test 2 active lever presses2.22.64.31.4-2.12.1-2.12.12.0-0.40.4-0.4
Progressive ratio test 2 breakpoint2.12.44.01.3-2.02.0-2.02.02.0-0.20.2-0.2
Progressive ratio test 2 inactive lever presses1.72.84.52.1-1.91.9-1.91.91.9-0.90.9-0.9
Incentive Sensitization - Responses0.91.31.81.3-1.31.3-1.31.31.3-0.70.7-0.7
Incentive Sensitization - Breakpoint0.91.21.71.3-1.21.2-1.21.21.2-0.60.6-0.6
Sum of active levers in priming session hrs 5-60.80.71.7-0.10.8-0.80.8-0.8-1.30.8-0.80.8
Progressive ratio0.20.30.8-0.30.3-0.30.3-0.3-0.20.9-0.90.9
Food seeking constrained by brief footshock0.10.10.3-0.1-0.30.3-0.30.30.50.2-0.20.2
Seeking ratio, punishment vs. effort0.10.10.20.1-0.10.1-0.10.10.2-0.50.5-0.5
Retroperitoneal fat weight1.98.210.4-2.73.2-3.23.2-3.2-3.22.3-2.32.3
Reaction time number correct2.14.15.80.8-2.42.4-2.42.42.2-1.61.6-1.6
Reaction time mean minus median0.10.20.2-0.30.4-0.40.4-0.4-0.40.5-0.50.5
Reaction time mean minus median AUC0.20.40.5-0.30.7-0.70.7-0.7-0.70.6-0.60.6
Reaction time num false alarms0.10.10.20.4-0.40.4-0.40.40.4-0.30.3-0.3
Reaction time num false alarms AUC0.30.40.60.4-0.80.8-0.80.80.8-0.50.5-0.5
Reaction time trials correct on left2.14.15.80.8-2.42.4-2.42.42.2-1.61.6-1.6
Reaction time trials on left2.34.36.20.9-2.52.5-2.52.52.2-1.71.7-1.7
Reaction time mean1.11.82.6-0.71.6-1.61.6-1.6-1.51.0-1.01.0
Reaction time mean AUC0.60.91.3-0.51.1-1.11.1-1.1-1.10.8-0.80.8
Median of all reaction times1.52.13.0-0.71.7-1.71.7-1.7-1.71.2-1.21.2
Reaction time omissions0.40.61.70.8-0.10.1-0.10.1-0.21.3-1.31.3
Reaction time false alarm rate0.30.40.60.10.7-0.70.7-0.7-0.60.5-0.50.5
Reaction time premature initiation rate0.20.30.4-0.40.6-0.60.6-0.6-0.50.4-0.40.4
Reaction time premature initiations0.10.30.30.1-0.60.6-0.60.60.6-0.40.4-0.4
Std. dev. reaction times0.20.40.5-0.50.7-0.70.7-0.7-0.70.5-0.50.5
Reaction time trials completed2.34.36.20.9-2.52.5-2.52.52.2-1.71.7-1.7
Reaction time trials AUC2.03.95.60.7-2.42.4-2.42.42.1-1.61.6-1.6
Run reversals in cocaine runway, females0.10.10.3-0.0-0.20.2-0.20.2-0.3-0.50.5-0.5
Run reversals in cocaine runway, males4.74.77.8-0.9-2.72.7-2.72.72.8-1.31.3-1.3
Latency to leave start box in cocaine runway2.12.33.9-1.61.1-1.11.1-1.1-1.22.0-2.02.0
Latency to leave start box in cocaine runway, F1.41.62.5-1.60.9-0.90.9-0.9-1.21.6-1.61.6
Latency to leave start box in cocaine runway, M0.70.71.2-0.60.7-0.70.7-0.7-0.61.1-1.11.1
Std. dev. time between licks in bursts0.00.10.6-0.80.0-0.00.0-0.0-0.1-0.00.0-0.0
Total sessions with >9 infusions0.60.70.9-0.8-0.90.9-0.90.90.90.9-0.90.9
Short access day 1 total inactive lever presses0.20.32.4-1.5-0.10.1-0.10.1-0.10.4-0.40.4
Short access day 10 total inactive lever presses0.71.64.7-0.5-0.30.3-0.30.30.2-2.22.2-2.2
Short access day 1 total infusions0.20.20.4-0.5-0.60.6-0.60.60.6-0.20.2-0.2
Short access day 10 total infusions0.91.21.8-0.6-1.31.3-1.31.31.30.7-0.70.7
Short access total infusions0.91.11.8-0.4-1.31.3-1.31.31.30.6-0.60.6
Short access day 1 locomotion0.20.20.4-0.4-0.60.6-0.60.60.6-0.10.1-0.1
Short access day 10 total locomotion0.40.71.21.10.9-0.90.9-0.9-1.0-0.40.4-0.4
Short access total locomotion0.20.20.40.20.3-0.30.3-0.3-0.50.6-0.60.6
One hour access (0.3 mA shock)4.75.48.62.1-2.92.9-2.92.92.9-0.70.7-0.7
Compulsive drug intake1.21.42.11.2-1.01.0-1.01.00.9-1.51.5-1.5
One hour access (shock baseline)0.60.91.10.6-1.01.0-1.01.01.00.9-0.90.9
Social response proportion7.48.412.1-1.72.7-2.72.7-2.7-2.63.5-3.53.5
Social responses0.10.10.4-0.20.1-0.10.1-0.10.10.6-0.60.6
Social time0.10.21.31.20.2-0.20.2-0.2-0.00.2-0.20.2
Soleus weight0.41.24.22.00.1-0.10.1-0.1-0.2-1.51.5-1.5
Bone: stiffness1.01.62.0-1.21.4-1.41.4-1.4-1.40.9-0.90.9
Tibialis anterior weight0.51.711.33.40.6-0.60.6-0.6-0.60.8-0.80.8
Time to tail flick, vehicle, before self-admin0.20.20.60.20.2-0.20.2-0.2-0.40.8-0.80.8
Time to tail flick, vehicle, after self-admin0.40.51.40.0-0.30.3-0.30.30.2-1.21.2-1.2
Time to tail flick, test, before self-admin0.80.91.41.1-1.21.2-1.21.20.90.1-0.10.1
Time to tail flick, test, after self-admin0.50.61.00.4-0.70.7-0.70.70.3-1.01.0-1.0
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.9-0.40.4-0.40.40.2-0.40.4-0.4
Delta time to tail flick, test, before/after SA0.40.40.70.90.4-0.40.4-0.4-0.7-0.70.7-0.7
Tibia length0.10.41.6-1.30.5-0.50.5-0.5-0.60.5-0.50.5
Ambulatory time before self-admin0.40.61.00.70.6-0.60.6-0.6-0.61.0-1.01.0
Ambulatory time after self-admin1.21.52.10.1-1.21.2-1.21.20.9-1.51.5-1.5
Bone: tissue strength0.70.70.9-0.50.9-0.90.9-0.9-0.90.7-0.70.7
Total heroin consumption0.80.91.60.6-1.31.3-1.31.31.10.2-0.20.2
Bone: trabecular number0.00.00.0-0.10.1-0.10.1-0.1-0.1-0.20.2-0.2
Bone: trabecular spacing0.10.10.6-0.80.0-0.00.0-0.0-0.1-0.20.2-0.2
Bone: trabecular thickness0.10.20.40.60.5-0.50.5-0.5-0.4-0.00.0-0.0
Bone: trabecular tissue density0.40.61.00.71.0-1.01.0-1.0-0.9-0.10.1-0.1
Water consumed over 24 hours2.33.14.21.1-1.71.7-1.71.71.7-2.02.0-2.0
Number of responses in last shaping day0.50.61.60.6-0.20.2-0.20.20.31.3-1.31.3