Hub : Genes

Car8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Car8 0.52 0.14 4.3e-08 0.23 0.23 0.19 0.25 4.4e-06 2.8e-06 2.4e-05 1.2e-06
2 PL alternative polyA NM_001009662.1 0.02 0.01 7.3e-03 0.01 0.01 0 0.01 3.2e-02 2.7e-02 7.7e-02 3.3e-02
3 Liver intron excision ratio chr5_26151723_26187671 0.11 0.05 8.3e-13 0.09 0.08 0.09 0.09 1.6e-10 5.1e-09 5.4e-10 2.4e-10
4 OFC gene expression Car8 0.87 0.06 2.8e-16 0.52 0.39 0.48 0.48 2.8e-14 3.3e-10 3.3e-13 7.0e-13
5 Brain isoform ratio XM_039109404.2 0.1 0.05 1.5e-05 0.05 0.05 0.03 0.03 1.3e-05 1.6e-05 3.6e-04 5.7e-04
6 PL gene expression Car8 0.44 0.14 0.0e+00 0.35 0.36 0.35 0.36 1.1e-39 1.7e-40 6.2e-40 1.7e-40
7 pVTA intron excision ratio chr5_26131717_26145468 0.03 0.02 6.7e-03 0.04 0.02 0.01 0.02 6.0e-04 1.5e-02 2.1e-02 1.4e-02
8 pVTA intron excision ratio chr5_26151723_26187671 0.03 0.02 3.0e-03 0.04 0.02 0.02 0.02 2.3e-04 7.3e-03 1.0e-02 7.2e-03
9 pVTA gene expression Car8 0.33 0.11 0.0e+00 0.22 0.24 0.26 0.26 2.7e-17 1.2e-19 1.6e-20 1.5e-20
10 Adipose gene expression Car8 0.14 0.06 1.4e-15 0.11 0.1 0.1 0.11 1.5e-12 9.3e-11 1.3e-11 4.5e-12
11 IC gene expression Car8 0.67 0.1 0.0e+00 0.45 0.53 0.51 0.54 1.2e-20 1.3e-25 1.5e-24 1.5e-26
12 BLA intron excision ratio chr5_26151723_26187671 0.06 0.04 7.8e-03 0.04 0.02 0.01 0.01 3.8e-03 3.0e-02 1.5e-01 6.6e-02
13 Liver intron excision ratio chr5_26147841_26151628 0.05 0.03 1.5e-03 0.01 0.01 0.01 0.01 9.5e-03 1.2e-02 5.3e-02 2.1e-02
14 Brain isoform ratio NM_001009662.1 0.09 0.04 3.8e-05 0.03 0.05 0.03 0.04 7.5e-04 1.6e-05 5.7e-04 9.0e-05
15 BLA gene expression Car8 0.17 0.08 5.8e-07 0.11 0.1 0.12 0.12 1.3e-06 4.2e-06 4.2e-07 6.7e-07
16 NAcc gene expression Car8 0.44 0.1 0.0e+00 0.51 0.51 0.52 0.52 6.0e-91 2.7e-89 2.1e-91 1.1e-91
17 Brain gene expression Car8 0.16 0.08 2.2e-06 0.03 0.06 0.06 0.05 4.9e-04 2.2e-06 1.8e-06 9.5e-06
18 Brain alternative polyA XM_039109404.2 0.17 0.07 2.3e-10 0.09 0.13 0.12 0.12 1.0e-08 4.0e-12 3.3e-11 7.4e-11
19 Brain alternative polyA NM_001009662.1 0.17 0.07 3.4e-10 0.07 0.12 0.12 0.11 7.1e-07 1.2e-11 5.3e-11 2.2e-10
20 PL intron excision ratio chr5_26151723_26187671 0.04 0.02 8.5e-05 0.04 0.03 0.03 0.03 2.2e-05 1.3e-04 5.4e-04 3.6e-04
21 RMTg gene expression Car8 0.3 0.13 1.5e-03 0.19 0.09 0.1 0.12 7.5e-06 2.9e-03 1.2e-03 4.3e-04
22 Liver gene expression Car8 0.05 0.03 2.6e-03 0.01 0.01 0 0.01 1.9e-02 7.1e-02 1.4e-01 6.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.20.42.40.9-0.0-0.0-0.10.60.00.2-0.21.30.30.20.30.3-0.50.40.4-0.20.5-0.50.61.5-0.9
Area under the delay curve0.80.92.50.20.4-1.1-1.4-0.3-1.30.5-0.5-1.0-0.8-1.6-1.21.2-0.1-1.0-1.40.00.1-0.1-1.3-1.41.1
BMI with tail0.72.55.3-1.3-2.31.01.21.41.2-1.91.9-0.32.21.71.40.6-1.91.51.8-1.42.1-2.11.80.91.0
BMI without tail0.41.43.1-0.8-1.70.60.71.00.6-1.31.3-0.01.61.10.90.8-1.61.01.2-1.11.8-1.71.20.91.0
Body weight0.93.89.71.5-0.8-2.7-2.42.2-2.50.0-0.00.60.0-1.8-1.33.1-3.0-1.9-1.3-1.53.0-2.9-1.10.72.4
Weight adjusted by age1.01.64.31.71.6-0.3-0.3-1.1-0.72.1-2.11.2-1.6-0.6-1.30.51.3-0.5-0.91.8-1.41.4-0.80.6-1.3
Bone surface0.20.41.41.20.5-0.6-0.90.3-0.60.8-0.81.0-0.4-0.7-0.60.9-0.3-0.2-0.4-0.10.3-0.3-0.20.9-0.5
Bone volume0.20.31.21.10.5-0.6-0.70.3-0.60.6-0.61.0-0.2-0.5-0.50.5-0.3-0.2-0.3-0.00.3-0.3-0.10.9-0.3
Breakpoint value in progressive ratio session0.20.21.0-0.40.00.40.20.40.3-0.50.50.50.70.40.2-1.0-0.1-0.10.50.70.5-0.50.60.40.4
Number of licking bursts0.30.42.20.10.80.2-0.0-1.0-0.20.4-0.4-0.5-0.1-0.3-0.9-0.81.0-0.5-0.61.5-0.80.8-0.3-0.80.2
Context. condit. distance diff. score3.03.77.3-2.3-1.52.52.5-0.02.7-2.42.4-0.12.32.62.3-2.6-0.02.02.5-0.10.4-0.52.40.4-0.2
Locomotion velocity, session 12.62.87.0-1.8-1.02.62.5-1.02.6-1.41.4-0.61.42.32.0-1.60.82.52.20.1-0.50.41.90.6-1.4
Locomotion distance, session 10.40.53.90.21.1-0.2-0.60.20.30.2-0.20.8-0.7-0.40.5-2.00.6-0.5-0.0-0.2-0.60.6-0.20.5-1.3
Locomotion velocity, session 21.71.94.3-1.8-0.22.11.9-1.91.9-0.90.9-1.50.61.41.1-1.81.71.51.10.8-1.51.41.0-1.1-0.7
Locomotion distance, session 20.60.92.90.71.6-0.5-1.1-0.2-0.20.9-0.90.5-1.4-1.0-0.5-1.21.0-1.0-0.70.1-1.21.2-0.70.1-1.7
Locomotion velocity, session 31.31.510.3-0.60.71.30.9-0.31.6-0.70.71.30.41.11.2-3.21.01.11.20.1-0.80.71.21.1-1.9
Locomotion distance, session 31.01.16.0-0.11.10.80.6-0.31.20.1-0.11.2-0.30.50.5-2.51.20.70.70.5-1.11.10.60.9-2.2
Stereotopy head waving bouts, day 31.41.64.91.40.6-1.5-2.20.8-1.80.8-0.81.6-0.4-1.8-1.61.7-1.2-0.7-0.9-0.61.5-1.6-0.70.71.0
Stereotopy head waving duration, day 30.81.02.81.20.5-1.3-1.70.9-1.40.5-0.51.5-0.4-1.3-1.00.9-1.0-1.0-0.7-0.81.1-1.1-0.50.90.2
Locomotion velocity, session 72.12.35.8-1.9-1.02.32.3-1.02.4-1.61.6-0.81.32.11.6-1.60.61.91.90.3-0.50.41.8-0.0-0.9
Locomotion distance, session 70.60.73.0-0.50.21.20.9-0.51.4-0.30.30.20.00.80.4-1.20.81.01.00.7-0.80.80.90.4-1.7
Stereotopy head waving bouts, day 70.70.71.80.8-0.1-1.3-1.01.4-1.10.2-0.21.0-0.1-0.60.20.8-1.3-1.0-0.6-1.31.0-0.9-0.40.90.3
Stereotopy head waving duration, day 70.70.93.50.2-0.6-0.5-0.41.6-0.1-0.60.61.20.60.11.00.0-1.5-0.10.4-1.91.3-1.30.51.4-0.2
Locomotion velocity, session 80.60.71.8-0.3-0.30.80.90.31.2-0.80.80.50.51.11.3-1.3-0.10.91.2-0.5-0.00.00.91.0-1.3
Locomotion distance, session 81.82.79.0-1.8-0.81.81.40.52.4-2.22.20.51.71.82.3-3.0-0.21.42.1-0.90.3-0.42.00.7-0.9
Degree of sensitization distance0.50.52.1-0.6-1.30.50.5-0.00.2-0.70.7-1.10.70.40.21.5-0.70.40.4-0.10.7-0.70.4-0.60.7
Degree of sensitization stereotypy0.20.31.30.0-0.3-0.70.10.9-0.2-0.20.20.1-0.10.21.1-0.4-0.6-0.8-0.2-1.00.00.0-0.10.4-0.4
Conditioned locomotion0.20.20.8-0.7-0.30.60.5-0.70.4-0.40.4-0.80.40.3-0.0-0.40.30.50.40.20.0-0.00.2-0.80.9
Cocaine response after cond. corrected1.01.22.7-1.6-0.51.31.5-1.31.5-0.90.9-1.60.51.10.8-1.41.10.90.90.6-1.00.90.4-1.50.4
Cocaine response after cond. not corrected1.82.18.1-2.0-0.61.61.9-2.11.5-0.70.7-2.90.41.20.6-0.91.71.00.61.0-1.61.60.1-2.60.7
Cocaine response before conditioning0.50.63.8-0.8-0.60.30.5-0.9-0.20.0-0.0-2.00.10.1-0.11.40.3-0.0-0.40.4-0.50.5-0.4-1.61.0
Saline control response1.11.47.10.8-0.4-0.4-0.12.2-0.0-0.20.22.50.90.70.7-0.3-1.60.40.9-1.01.5-1.51.02.7-0.5
Bone: connectivity density0.30.53.00.80.30.30.10.30.50.2-0.21.2-0.00.30.5-0.4-0.00.60.6-0.2-0.10.10.71.6-1.7
Bone: cortical apparent density0.91.33.9-1.3-1.01.81.8-1.71.4-0.60.6-2.00.71.20.20.30.91.41.10.7-0.70.60.6-1.40.1
Bone: cortical area0.20.30.91.00.6-0.8-0.90.3-0.80.5-0.50.7-0.3-0.8-0.70.0-0.2-0.9-0.60.20.3-0.3-0.40.20.4
Bone: cortical porosity0.20.20.9-0.3-0.6-0.2-0.10.5-0.3-0.30.3-0.60.30.00.40.7-0.5-0.4-0.3-0.20.4-0.3-0.0-0.30.9
Bone: cortical porosity0.40.41.90.1-0.8-0.5-0.31.4-0.4-0.40.40.30.40.10.60.7-1.2-0.4-0.1-0.80.9-0.90.30.60.4
Bone: cortical thickness0.20.41.21.00.7-0.9-0.80.6-0.80.4-0.40.9-0.4-0.6-0.2-0.6-0.2-1.1-0.6-0.00.1-0.1-0.40.50.0
Bone: cortical thickness0.10.10.60.0-0.3-0.2-0.40.3-0.2-0.00.0-0.20.0-0.30.30.8-0.4-0.5-0.1-0.40.2-0.2-0.2-0.2-0.1
Bone: cortical tissue density0.91.23.8-1.2-0.91.71.7-1.71.3-0.50.5-1.90.61.10.10.40.91.31.00.8-0.70.60.5-1.40.1
Condit. Reinf. active minus inactive responses0.20.20.8-0.20.10.50.3-0.20.6-0.20.20.00.00.40.8-0.70.30.10.2-0.2-0.50.50.50.4-0.9
Condit. Reinf. active-inactive response ratio0.30.41.30.50.8-0.10.1-0.50.10.6-0.60.1-0.7-0.10.1-0.90.9-0.3-0.40.4-1.11.1-0.30.2-1.0
Condit. Reinf. active responses0.60.82.1-0.9-0.90.80.50.41.0-1.21.20.10.90.81.4-0.3-0.70.71.0-1.20.6-0.71.30.7-0.4
Condit. Reinf. inactive responses1.82.24.8-1.2-1.90.70.31.30.9-1.91.90.31.81.01.50.8-2.01.11.5-2.02.1-2.21.71.00.5
Incentive salience index mean0.20.20.7-0.6-0.20.80.4-0.50.8-0.30.3-0.50.30.30.5-0.30.30.50.5-0.3-0.30.30.60.0-0.6
Condit. Reinf. lever presses0.50.71.4-1.0-1.11.10.60.21.0-0.90.9-0.61.10.70.70.3-0.51.11.1-0.90.6-0.71.20.3-0.1
Condit. Reinf. active minus inactive responses0.20.31.5-0.1-0.40.70.9-0.40.60.2-0.2-0.20.20.70.40.80.31.20.5-0.2-0.40.30.50.4-1.0
Condit. Reinf. active-inactive response ratio0.30.41.10.10.10.50.5-1.10.40.6-0.6-0.9-0.50.1-0.30.90.90.7-0.10.5-1.01.0-0.1-0.3-0.9
Condit. Reinf. active responses0.30.41.5-0.2-0.70.40.60.20.5-0.20.20.30.70.70.60.6-0.41.20.7-0.90.4-0.40.70.7-0.4
Condit. Reinf. inactive responses0.50.71.6-0.8-1.00.20.40.80.2-0.80.80.51.30.70.80.2-1.10.80.7-1.01.2-1.20.80.41.0
Condit. Reinf. lever presses0.10.10.7-0.1-0.60.10.6-0.10.10.0-0.0-0.50.20.50.50.8-0.10.40.2-0.30.0-0.00.0-0.10.2
Condit. Reinf. lever reinforcers received0.30.41.9-0.3-0.70.60.80.00.6-0.20.20.20.70.90.70.5-0.21.40.8-0.50.3-0.30.80.7-0.4
Conditioned reinforcement - actives0.61.04.2-0.40.5-0.00.0-2.0-0.30.4-0.4-1.5-0.1-0.5-1.10.31.30.0-0.81.9-0.90.9-0.9-1.81.0
Conditioned reinforcement - inactives0.50.81.8-1.0-0.11.31.4-1.01.2-0.40.4-0.00.71.10.4-1.20.91.30.81.0-0.60.60.9-0.6-0.2
Conditioned locomotion0.91.25.9-1.5-0.10.50.6-2.20.2-0.30.3-2.30.1-0.1-0.30.21.30.3-0.50.9-1.21.2-0.5-2.40.8
Patch foraging indifference point 0 sec3.26.012.73.53.6-2.5-2.70.0-2.43.4-3.42.3-3.4-2.9-2.4-0.71.4-2.9-2.41.2-1.71.8-2.40.7-1.6
Patch foraging indifference point AUC1.11.66.5-1.5-1.80.2-0.1-0.6-0.2-1.11.1-2.51.0-0.10.12.6-1.00.4-0.1-0.91.2-1.2-0.2-1.82.4
Delay disc. indifference point, 0s delay2.73.07.71.52.6-1.2-1.6-1.3-1.42.4-2.40.7-2.0-1.8-2.3-0.41.8-1.3-1.92.8-1.71.7-1.8-0.4-0.5
Delay disc. indifference point, 16s delay0.80.93.3-0.7-1.3-0.2-0.40.4-0.4-0.70.7-1.40.6-0.3-0.11.8-1.2-0.1-0.2-0.81.2-1.2-0.2-1.01.8
Delay disc. indifference point, 2s delay0.30.40.90.10.6-0.6-0.7-0.8-0.60.6-0.6-0.4-0.6-1.0-1.00.40.5-0.1-0.80.2-0.40.4-0.9-0.90.3
Delay disc. indifference point, 24s delay1.11.35.0-1.2-1.5-0.4-0.50.6-0.4-1.21.2-1.80.9-0.30.11.5-1.4-0.2-0.4-1.11.4-1.4-0.2-1.32.2
Delay disc. indifference point, 4s delay1.21.23.20.51.0-1.3-1.6-0.5-1.31.0-1.0-0.7-1.5-1.8-1.20.80.5-1.5-1.6-0.0-0.70.7-1.5-1.20.2
Delay disc. indifference point, 8s delay1.11.23.20.80.8-1.4-1.6-0.2-1.50.9-0.9-0.6-1.4-1.8-1.41.00.1-1.4-1.70.1-0.30.3-1.4-1.20.5
Indifference point function ln k0.50.95.70.40.70.41.20.20.90.3-0.31.2-0.41.00.7-2.40.80.10.80.2-1.11.10.61.0-1.9
Indifference point function log k0.50.95.70.40.70.41.20.20.90.3-0.31.2-0.41.00.7-2.40.80.10.80.2-1.11.10.61.0-1.9
Patch foraging total patch changes 0 sec3.56.513.73.73.7-2.7-2.80.1-2.63.6-3.62.5-3.5-2.9-2.5-0.61.4-3.0-2.51.2-1.71.8-2.50.8-1.7
Patch foraging total patch changes 12 sec0.91.23.91.30.7-1.6-2.00.6-1.61.1-1.10.4-1.0-1.7-0.91.1-0.6-1.6-1.2-0.70.4-0.4-1.2-0.10.3
Patch foraging total patch changes 18 sec0.50.81.91.41.0-1.1-1.20.2-1.21.3-1.30.7-1.0-1.1-0.90.40.1-1.0-0.90.3-0.10.2-1.00.4-0.1
Patch foraging total patch changes 24 sec2.84.811.23.12.8-2.1-2.2-0.5-2.23.3-3.31.3-3.1-2.4-2.30.51.4-2.2-2.41.3-1.81.8-2.40.3-1.3
Patch foraging total patch changes 6 sec1.82.85.51.82.1-1.4-1.5-1.2-1.72.3-2.30.1-2.2-2.0-2.20.31.5-1.6-1.91.9-1.41.4-2.1-0.8-0.0
Patch foraging time to switch 0 sec0.30.63.10.30.30.3-0.00.70.7-0.10.11.80.30.30.5-1.1-0.30.61.0-0.10.4-0.40.91.5-1.4
Patch foraging water rate 0 sec0.10.31.01.00.6-0.7-0.60.2-0.60.7-0.70.6-0.7-0.6-0.60.40.0-0.5-0.60.2-0.10.1-0.60.40.1
Patch foraging water rate 12 sec3.26.614.23.63.5-2.8-2.2-0.4-2.73.4-3.41.4-3.8-2.6-2.9-0.31.8-3.1-2.91.8-2.32.4-3.00.0-0.9
Patch foraging water rate 18 sec5.88.918.63.74.0-3.1-2.8-0.9-3.34.0-4.01.4-3.7-3.4-4.30.22.1-3.4-3.72.5-2.22.3-3.6-0.5-0.1
Patch foraging water rate 24 sec1.82.67.72.82.3-2.0-1.70.8-1.61.9-1.92.6-1.9-1.5-1.8-0.80.4-1.6-1.30.6-0.50.5-1.31.6-0.8
Patch foraging water rate 6 sec0.81.22.71.51.6-0.9-0.3-0.5-0.71.3-1.30.5-1.6-0.7-0.9-0.91.3-1.2-1.01.0-1.51.5-1.2-0.0-0.5
Seeking ratio, delayed vs. immediate footshock0.70.82.9-0.6-0.6-0.1-0.21.70.4-1.11.10.70.90.50.9-0.8-1.2-0.10.9-1.51.2-1.20.80.9-0.1
Distance traveled before self-admin0.50.61.70.30.7-0.4-0.2-1.3-0.50.6-0.6-1.0-0.9-0.7-0.9-0.11.0-0.5-0.90.5-1.01.0-1.0-1.30.5
Distance traveled after self-admin1.01.24.2-1.8-0.81.41.5-1.61.2-1.31.3-2.00.91.01.0-0.90.80.70.3-0.2-0.80.70.7-1.20.5
Extensor digitorum longus weight1.97.616.04.03.4-3.8-3.50.3-3.63.4-3.42.0-3.3-3.5-3.30.70.7-3.3-3.41.5-0.80.9-3.30.40.0
Bone: elastic displacement2.02.36.6-0.80.90.61.1-2.50.40.6-0.6-2.3-0.90.1-0.9-1.32.6-0.3-0.82.2-2.52.5-1.0-2.30.6
Bone: elastic work0.50.72.00.20.5-0.8-0.6-0.6-0.90.4-0.4-1.0-0.7-0.9-0.80.10.5-1.3-1.20.6-0.60.7-1.0-1.41.1
Bone: endosteal estimation0.10.31.10.2-0.2-0.4-0.60.4-0.4-0.10.10.40.4-0.4-0.50.8-0.70.1-0.1-0.11.0-1.1-0.00.21.1
Bone: endosteal perimeter0.00.10.5-0.3-0.1-0.1-0.3-0.1-0.1-0.30.3-0.20.1-0.3-0.2-0.1-0.1-0.2-0.0-0.20.3-0.4-0.0-0.50.7
Epididymis fat weight1.65.613.3-2.4-3.00.80.51.91.2-3.63.6-0.63.41.52.4-0.2-3.01.12.0-2.53.4-3.42.00.22.7
Delta time in closed arm before/after self-admin0.60.62.50.80.6-1.2-1.30.5-1.00.5-0.50.0-1.0-1.2-0.40.4-0.2-1.6-1.0-0.6-0.10.2-0.9-0.0-0.1
Delta time in open arm before/after self-admin0.50.51.8-0.1-0.90.00.30.9-0.2-0.30.30.20.90.4-0.30.8-1.10.40.1-0.11.3-1.30.50.51.1
Diff in mean of infusions in LGA sessions0.30.41.7-0.10.50.60.6-0.40.80.1-0.10.4-0.20.50.3-1.30.90.10.50.9-0.90.90.40.9-1.0
Delay discount exponential model param0.80.92.40.0-0.01.01.30.31.2-0.30.31.30.71.51.0-1.50.30.91.30.3-0.20.21.21.6-1.3
Extinction: sum of active levers before priming0.70.81.71.31.2-0.8-0.80.5-0.61.2-1.21.2-1.0-0.8-0.9-0.40.3-0.8-0.70.5-0.40.4-0.71.2-0.9
Active lever presses in extinction session 60.80.82.31.31.5-0.7-0.70.2-0.81.2-1.21.3-1.0-0.7-1.1-1.00.7-1.1-0.90.6-0.60.6-0.70.7-0.4
Bone: final force1.01.63.81.81.1-1.5-1.9-0.1-1.81.3-1.30.6-1.1-1.8-2.01.4-0.2-1.4-1.40.70.3-0.3-1.3-0.10.8
Bone: final moment1.01.53.71.81.1-1.6-1.90.2-1.81.2-1.20.8-1.1-1.8-1.71.2-0.3-1.5-1.50.50.3-0.3-1.30.10.7
Food consumed during 24 hour testing period0.20.21.40.10.50.20.4-0.50.40.5-0.50.60.30.3-0.3-0.70.70.50.11.2-0.30.30.00.5-0.0
Glucose0.20.21.6-0.10.2-0.5-0.20.2-0.60.2-0.2-0.00.1-0.2-0.9-0.1-0.1-0.6-0.60.90.3-0.2-0.5-0.01.3
Heart weight2.03.28.12.21.4-2.9-2.81.6-2.61.4-1.41.8-1.5-2.2-1.70.9-1.0-2.7-2.2-0.30.7-0.7-1.91.00.8
Delay discount hyperbolic model param1.01.12.9-0.2-0.41.21.50.51.4-0.70.71.21.01.71.3-1.4-0.11.11.50.10.2-0.21.41.6-1.0
Intermittent access intake day 1-15 change0.00.10.3-0.60.10.30.4-0.20.3-0.20.2-0.10.50.40.2-0.50.20.30.20.4-0.00.00.2-0.20.1
Intermittent access intake escalation0.10.31.0-0.70.20.60.7-0.90.4-0.00.0-0.50.40.50.1-0.40.70.50.21.0-0.50.50.1-0.6-0.0
Intermittent access intake escalation 20.20.32.1-0.40.2-0.10.1-1.0-0.20.2-0.2-0.80.1-0.1-0.50.30.6-0.2-0.41.5-0.40.4-0.5-0.80.5
Intermitt. access day 1 inactive lever presses0.10.41.40.61.2-0.1-0.2-0.3-0.20.8-0.80.9-0.6-0.3-0.6-1.01.00.4-0.80.6-0.80.8-0.30.3-0.1
Intermitt. access day 15 inactive lever presses0.20.41.50.61.2-0.3-0.5-0.2-0.30.8-0.80.8-0.5-0.3-0.6-1.20.70.1-0.61.2-0.50.5-0.50.2-0.0
Intermitt. access escalation Index0.60.82.90.6-0.4-1.2-1.21.4-1.10.0-0.0-0.1-0.4-1.0-0.11.4-1.3-0.6-0.7-1.70.9-0.9-0.6-0.50.3
Intermittent access day 1 total infusions1.01.66.7-0.60.5-0.4-0.4-2.3-0.80.4-0.4-2.2-0.2-1.0-1.60.41.3-0.5-1.31.8-1.00.9-1.4-2.61.7
Intermittent access day 15 total infusions1.01.46.3-0.80.90.30.4-2.5-0.10.5-0.5-1.5-0.1-0.3-1.0-0.61.90.0-0.72.3-1.61.6-0.8-1.90.6
Intermittent access terminal intake (last 3 days)1.11.56.4-1.50.20.60.8-2.50.3-0.20.2-2.00.60.2-0.6-0.61.60.4-0.32.3-1.11.1-0.4-2.21.2
Intermittent access total infusions1.11.46.2-0.70.90.30.4-2.5-0.00.5-0.5-1.4-0.1-0.2-1.1-0.81.90.1-0.72.3-1.51.5-0.8-1.70.8
Intermittent access day 1 locomotion1.21.57.7-0.80.70.60.6-2.80.20.4-0.4-1.6-0.3-0.2-0.7-0.72.10.1-0.61.9-1.91.9-0.6-2.00.6
Intermittent access day 15 total locomotion0.91.65.7-0.11.50.60.6-2.40.31.1-1.1-0.3-0.6-0.0-0.9-1.52.40.2-0.52.2-2.12.1-0.5-0.6-0.3
Intermittent access total locomotion1.31.66.4-0.80.81.31.4-2.50.90.3-0.3-0.8-0.00.6-0.1-1.72.30.90.12.0-2.02.00.1-0.8-0.1
Intermittent access standard deviation0.20.52.2-1.2-0.70.40.4-0.90.0-0.50.5-1.50.80.1-0.20.80.10.3-0.30.00.1-0.1-0.0-1.21.2
Left kidney weight0.52.16.50.7-0.8-1.7-1.62.4-1.6-0.50.50.90.7-0.7-0.71.8-2.4-1.0-0.8-0.92.5-2.5-0.30.92.1
Right kidney weight0.20.82.5-0.1-0.8-0.7-0.81.2-0.8-0.70.7-0.20.7-0.3-0.31.1-1.4-0.6-0.4-0.61.5-1.5-0.1-0.11.6
Cocaine induced anxiety1.11.64.40.20.81.41.6-0.41.40.5-0.51.9-0.21.40.8-2.11.11.41.31.1-1.11.11.22.0-2.0
Post-drug Anxiety0.30.31.20.50.9-0.10.0-0.2-0.10.6-0.60.8-0.6-0.1-0.2-1.10.7-0.2-0.00.8-0.60.6-0.20.3-0.4
Baseline Anxiety1.92.25.90.20.0-2.0-2.30.3-2.00.0-0.0-1.6-0.4-2.0-1.41.7-0.8-2.0-1.8-0.50.9-0.8-1.9-2.42.2
Tail length1.04.09.91.91.0-2.7-2.6-0.1-3.11.7-1.7-0.3-1.7-2.7-2.62.7-0.6-2.9-2.80.50.5-0.4-2.5-1.12.2
Length with tail2.510.827.23.71.3-5.2-5.01.8-5.22.2-2.20.8-2.4-4.5-3.64.2-2.3-4.5-4.1-0.52.0-1.9-3.8-0.32.9
Length without tail1.96.116.12.70.5-4.0-3.82.4-3.81.0-1.01.2-1.3-3.2-2.53.1-2.6-3.0-2.5-1.22.5-2.4-2.40.42.1
Times rat made contact with spout0.70.83.20.7-0.2-0.8-0.51.8-0.3-0.20.21.50.20.00.70.1-1.3-0.40.3-1.61.0-1.00.41.7-1.0
Lifetime Intake1.31.57.7-0.70.90.30.4-2.8-0.00.5-0.5-1.6-0.2-0.3-1.1-0.72.10.1-0.72.3-1.71.7-0.8-1.70.8
Liver weight, left0.50.92.50.2-0.6-1.2-1.20.7-1.0-0.40.4-0.1-0.0-1.0-0.51.6-1.5-0.9-0.6-1.31.4-1.4-0.5-0.21.3
Liver weight, right1.52.66.42.42.5-1.7-1.4-0.1-1.62.1-2.12.0-2.0-1.3-1.6-0.91.0-1.6-1.61.5-1.11.2-1.41.2-1.1
Locomotor activity2.84.49.52.52.6-3.1-2.90.7-3.02.1-2.11.6-1.8-2.8-3.0-0.20.2-2.8-2.70.70.2-0.1-2.7-0.01.5
Locomotor testing distance1.62.85.72.12.3-2.3-2.40.7-2.21.9-1.92.0-1.4-2.1-2.2-0.50.1-2.0-1.90.70.1-0.0-1.90.70.6
Locomotor testing rearing2.95.912.83.33.6-2.7-2.4-0.0-2.73.4-3.42.8-2.9-2.4-2.9-0.51.4-2.5-2.71.9-1.51.5-2.51.4-1.1
Locomotion in novel chamber1.31.74.81.72.2-0.5-0.3-0.2-0.51.9-1.92.2-1.3-0.4-1.0-1.71.3-0.8-0.51.4-1.31.3-0.51.3-1.1
Locomotion in novel chamber post-restriction1.93.08.11.32.8-0.7-0.4-1.7-0.72.0-2.01.1-2.2-1.1-1.4-2.22.5-1.2-0.92.4-2.52.5-1.4-0.4-1.6
Fecal boli incidents, locomotor time 10.60.92.2-0.5-0.60.50.41.50.7-0.80.81.40.80.81.1-1.1-0.90.61.0-0.91.0-1.01.11.4-0.5
Change in fecal boli incidents, locomotor task0.80.83.0-0.30.60.40.0-1.7-0.00.2-0.2-1.4-0.2-0.2-0.8-0.31.30.3-0.61.7-1.00.9-0.4-1.70.8
Time >=10cm from walls, locomotor time 10.40.51.70.71.2-0.5-0.5-0.2-0.40.5-0.50.4-0.8-0.5-0.4-1.30.8-0.9-0.61.0-0.70.7-0.5-0.2-0.0
Bouts of movement, locomotor time 10.60.73.30.0-0.30.50.41.20.5-0.00.01.60.70.80.4-0.1-0.80.80.9-0.60.7-0.70.91.8-1.0
Total resting periods, locomotor time 10.60.74.30.40.20.30.21.10.40.4-0.42.00.20.60.2-0.5-0.40.60.7-0.30.4-0.40.72.1-1.4
Rest time, locomotor task time 11.92.311.22.12.3-1.2-1.11.4-0.51.4-1.43.4-1.5-0.6-0.5-2.60.4-0.9-0.40.4-0.50.6-0.52.4-1.9
Distance moved, locomotor task time 11.01.59.8-1.2-1.40.30.2-1.5-0.0-0.80.8-3.10.3-0.30.02.5-0.1-0.3-0.3-0.6-0.10.0-0.3-2.61.4
Vertical activity count, locomotor time 10.51.37.1-1.3-1.50.70.6-1.30.3-0.70.7-2.70.80.20.12.4-0.20.20.2-0.20.2-0.20.2-2.01.5
Time >=10cm from walls, locomotor time 20.40.63.30.10.90.40.1-0.30.80.3-0.30.8-0.70.10.6-1.61.00.00.40.1-1.11.10.40.3-1.8
Bouts of movement, locomotor time 20.20.31.60.50.50.3-0.10.3-0.00.8-0.81.0-0.4-0.0-0.20.10.20.5-0.2-0.3-0.30.30.21.1-1.3
Total resting periods, locomotor time 20.20.42.20.60.60.2-0.30.7-0.10.8-0.81.3-0.5-0.1-0.2-0.1-0.00.4-0.2-0.5-0.10.20.21.4-1.5
Rest time, locomotor task time 20.50.73.70.60.5-0.8-0.71.9-0.4-0.20.21.5-0.1-0.10.1-1.5-0.8-0.7-0.1-0.60.7-0.7-0.11.20.1
Distance moved, locomotor task time 20.91.15.6-0.20.40.40.2-2.40.20.7-0.7-1.6-0.8-0.5-0.60.81.50.1-0.41.0-1.61.5-0.6-1.8-0.4
Vertical activity count, locomotor time 20.91.26.3-0.50.40.80.6-2.50.30.7-0.7-1.7-0.6-0.1-0.40.51.70.1-0.11.2-1.81.7-0.3-1.9-0.6
Light reinforcement 10.61.63.81.12.0-0.8-0.8-1.4-0.81.4-1.40.2-1.5-1.0-1.1-1.41.7-1.1-1.21.7-1.51.5-1.4-0.6-0.1
Light reinforcement 21.32.04.21.51.9-0.5-0.3-1.5-0.72.0-2.00.3-1.8-0.7-1.4-0.51.9-0.8-1.11.9-1.91.9-1.4-0.0-1.1
Bone: marrow area0.10.31.10.3-0.2-0.4-0.70.4-0.5-0.00.00.30.3-0.5-0.60.9-0.70.1-0.2-0.11.0-1.0-0.10.21.1
Bone: maximum diameter0.30.61.70.70.3-1.0-1.30.5-1.10.2-0.20.6-0.1-1.0-0.90.4-0.7-0.9-0.6-0.11.0-1.0-0.5-0.01.3
Bone: maximum force0.50.82.41.40.6-1.2-1.50.5-1.30.7-0.70.8-0.4-1.3-1.21.0-0.6-1.0-0.90.10.7-0.7-0.70.20.7
Bone: maximum moment0.50.92.51.40.6-1.3-1.60.7-1.40.7-0.70.9-0.4-1.3-1.00.8-0.6-1.2-1.0-0.00.7-0.7-0.70.40.6
Mean time between licks in bursts0.51.22.81.21.6-1.1-1.2-0.4-1.01.2-1.20.3-1.6-1.3-1.1-0.61.0-1.7-1.20.7-1.11.1-1.3-0.5-0.3
Mean num. licks in bursts0.91.45.60.1-1.1-0.4-0.12.10.2-0.70.71.40.50.51.60.6-1.80.51.0-2.41.4-1.40.81.9-0.7
Cd content in liver1.31.53.2-1.4-1.81.01.20.61.3-1.81.8-0.41.51.51.80.1-1.10.71.4-1.20.9-0.91.50.3-0.2
Co content in liver0.91.13.41.51.6-0.6-0.4-0.3-0.21.3-1.31.3-1.4-0.5-0.6-1.21.0-0.3-0.50.6-1.21.2-0.71.0-1.8
Cu content in liver0.60.71.61.20.9-1.0-1.0-0.2-1.01.3-1.30.4-1.2-1.0-0.70.80.3-0.5-1.00.1-0.50.5-1.1-0.0-0.4
Fe content in liver0.40.51.3-1.1-0.41.00.9-0.51.1-0.70.7-0.30.60.80.5-0.70.40.80.80.0-0.40.40.7-0.3-0.5
K content in liver0.20.21.4-0.0-0.30.10.0-0.3-0.30.2-0.2-0.40.3-0.0-0.71.1-0.20.6-0.20.50.5-0.5-0.2-0.31.2
Mg content in liver0.30.31.9-0.4-0.6-0.1-0.20.2-0.3-0.20.2-0.40.6-0.1-0.31.0-0.60.2-0.2-0.00.8-0.80.0-0.31.4
Mn content in liver0.60.71.50.90.1-1.1-1.21.0-1.20.3-0.30.8-0.1-0.9-0.81.0-1.0-0.3-0.8-0.91.0-1.0-0.50.50.7
Na content in liver0.20.20.80.00.40.30.3-0.60.40.4-0.40.1-0.4-0.0-0.7-0.20.70.90.20.6-0.60.5-0.00.0-0.7
Rb content in liver3.03.48.22.91.6-2.6-2.81.9-2.21.8-1.82.7-1.7-2.2-1.51.3-1.0-1.8-1.6-1.10.8-0.7-1.42.1-0.8
Se content in liver0.70.84.5-0.2-0.5-0.7-0.8-0.3-1.0-0.00.0-0.60.2-0.7-1.01.9-0.7-0.7-0.70.31.0-1.0-0.6-0.92.1
Sr content in liver1.31.15.0-0.7-0.01.21.20.31.6-0.70.70.80.61.41.3-2.20.41.21.4-0.1-0.40.31.21.1-1.5
Zn content in liver0.20.21.5-0.1-0.60.1-0.10.2-0.0-0.10.10.00.50.10.11.2-0.60.20.3-0.00.7-0.70.20.30.4
Bone: minimum diameter0.10.10.80.30.4-0.3-0.20.2-0.20.1-0.10.60.2-0.1-0.3-0.50.00.1-0.20.70.3-0.3-0.00.10.9
Time in familiar zone, hab. session 11.31.24.8-1.2-0.21.41.8-0.51.6-1.01.0-0.20.91.61.2-2.20.81.21.30.2-0.60.61.10.1-0.7
Time in novel zone, hab. session 10.40.41.31.00.4-0.8-1.10.7-0.70.6-0.60.9-0.5-0.9-0.50.6-0.5-0.6-0.6-0.40.4-0.4-0.40.7-0.2
Total zone transitions, hab. session 10.81.24.71.31.7-0.9-1.50.2-0.61.0-1.01.1-1.6-1.4-0.6-0.80.6-1.1-0.6-0.5-0.90.8-0.80.5-2.2
Total locomotion distance, hab. session 10.60.81.90.61.3-0.5-1.2-0.9-0.51.1-1.10.1-1.3-1.4-1.10.30.9-0.5-0.80.4-0.90.8-1.0-0.4-1.0
Locomotion velocity, hab. session 10.60.92.30.71.2-0.7-1.3-0.8-0.81.2-1.20.1-1.4-1.5-1.30.90.7-0.6-0.90.5-0.60.6-1.1-0.6-0.6
Time in familiar zone, hab. session 20.30.30.8-0.4-0.70.40.70.10.3-0.70.7-0.10.90.80.5-0.2-0.40.60.6-0.00.6-0.60.60.10.8
Time in novel zone, hab. session 20.20.20.80.10.4-0.4-0.80.0-0.30.3-0.3-0.4-0.7-0.8-0.20.20.2-0.9-0.6-0.3-0.50.5-0.6-0.4-0.5
Total zone transitions, hab. session 20.40.63.1-0.20.30.1-0.30.50.7-0.60.60.3-0.4-0.11.2-1.60.1-0.40.5-1.5-0.40.40.20.2-1.8
Total locomotion distance, hab. session 20.30.31.2-0.30.4-0.0-0.7-0.50.2-0.00.0-0.7-0.8-0.80.2-0.20.5-0.5-0.3-1.0-0.70.7-0.7-1.1-0.6
Locomotion velocity, hab. session 20.20.31.1-0.30.30.0-0.5-0.50.2-0.10.1-0.6-0.8-0.70.3-0.10.4-0.3-0.2-1.0-0.60.6-0.5-0.9-0.7
Novel to familiar place preference ratio1.31.48.1-0.3-2.0-0.6-0.30.8-0.6-0.80.8-1.30.5-0.20.42.8-2.0-0.4-0.1-2.01.5-1.50.0-0.51.3
Novelty place preference1.61.88.7-0.6-2.2-0.5-0.20.8-0.6-1.11.1-1.60.8-0.10.52.9-2.1-0.4-0.0-2.11.7-1.70.1-0.71.6
Time in novel zone, NPP test1.61.78.0-0.6-2.2-0.5-0.10.8-0.5-1.11.1-1.60.80.00.62.8-2.1-0.30.0-2.01.7-1.60.2-0.61.6
Total zone transitions, NPP test0.50.73.50.90.9-0.5-0.91.0-0.00.2-0.21.7-0.5-0.40.4-1.3-0.2-0.50.1-1.0-0.00.00.21.5-1.9
Total locomotion distance, NPP test0.20.21.00.40.7-0.1-0.8-0.3-0.00.5-0.50.5-0.6-0.8-0.30.20.40.0-0.2-0.2-0.30.2-0.20.2-1.0
Locomotion velocity, NPP test0.10.21.10.30.70.1-0.6-0.40.10.4-0.40.4-0.6-0.6-0.20.00.40.2-0.1-0.3-0.40.3-0.10.1-1.1
Intraocular pressure0.91.33.7-0.8-1.6-0.4-0.40.9-0.3-1.21.2-0.51.0-0.10.61.5-1.9-0.20.3-1.61.9-1.90.3-0.21.6
Delta distance traveled before/after self-admin2.83.06.4-2.3-2.02.02.00.32.1-2.42.4-0.72.32.22.5-1.1-0.71.51.9-1.10.8-0.92.20.50.0
Delta ambulatory time before/after self-admin1.72.14.5-1.9-1.81.51.50.61.6-2.12.1-0.72.01.72.1-0.6-0.91.21.3-1.21.0-1.01.70.40.3
Parametrial fat weight0.61.54.60.1-1.5-0.2-0.21.9-0.0-0.90.90.71.10.50.71.2-2.10.71.0-1.82.1-2.10.91.40.6
Pavlov. Cond. lever latency0.30.42.00.10.6-0.1-0.1-1.0-0.40.5-0.5-0.4-0.4-0.4-0.70.10.8-0.3-0.61.4-0.60.6-0.7-0.80.6
Pavlov. Cond. magazine entry latency1.11.43.51.60.9-1.9-1.60.7-1.71.2-1.20.5-1.3-1.4-1.30.9-0.3-1.7-1.6-0.20.00.1-1.50.20.4
Pavlov. Cond. change in total contacts0.90.92.41.40.5-1.5-1.51.1-1.10.7-0.71.0-0.9-1.1-0.40.8-0.9-1.2-0.8-0.90.6-0.5-0.70.9-0.3
Pavlov. Cond. index score0.60.72.01.00.2-1.4-1.21.2-1.10.4-0.40.7-0.6-1.0-0.50.7-1.0-1.1-0.8-1.20.7-0.6-0.70.60.2
Pavlov. Cond. latency score0.50.72.10.9-0.0-1.3-1.21.4-0.90.2-0.20.8-0.4-0.8-0.30.5-1.2-0.9-0.5-1.40.9-0.9-0.40.70.2
Pavlov. Cond. lever contacts0.30.41.80.3-0.3-0.3-0.21.30.1-0.30.30.80.20.20.5-0.3-0.8-0.00.4-1.40.6-0.60.41.0-0.6
Pavlov. Cond. magazine entry number1.31.74.2-1.9-1.02.11.7-0.81.9-1.41.4-0.81.41.51.3-0.90.31.91.80.2-0.0-0.11.6-0.4-0.3
Pavlov. Cond. intertrial magazine entries1.82.25.6-1.3-1.01.91.40.12.1-1.51.50.71.51.62.0-1.3-0.41.82.1-1.00.6-0.72.41.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.41.00.3-1.2-1.01.0-0.90.5-0.50.8-0.6-0.8-0.40.3-0.7-0.9-0.6-1.00.4-0.4-0.60.7-0.2
Pavlov. Cond. response bias0.50.61.61.20.5-1.3-1.00.8-1.10.8-0.80.6-0.8-0.8-0.50.5-0.4-1.1-1.0-0.50.1-0.0-0.80.6-0.1
Pavlov. Cond. lever latency0.20.31.10.71.1-0.3-0.80.0-0.40.5-0.50.9-0.6-0.8-0.7-0.70.4-0.6-0.50.2-0.30.3-0.30.3-0.7
Pavlov. Cond. magazine entry latency0.91.13.80.10.30.10.1-1.9-0.40.7-0.7-1.8-0.7-0.5-1.10.91.3-0.4-0.81.8-1.11.1-1.0-1.90.7
Pavlov. Cond. change in total contacts0.10.21.2-0.0-0.4-0.30.2-0.6-0.3-0.00.0-1.0-0.2-0.10.10.70.1-0.4-0.20.2-0.20.2-0.4-1.10.7
Pavlov. Cond. index score0.20.31.6-0.1-0.4-0.10.2-0.7-0.30.1-0.1-1.3-0.1-0.1-0.21.00.2-0.2-0.30.6-0.20.3-0.5-1.20.9
Pavlov. Cond. latency score0.40.62.5-0.20.00.10.5-1.3-0.10.3-0.3-1.6-0.4-0.1-0.30.41.0-0.3-0.41.1-1.01.0-0.7-1.50.6
Pavlov. Cond. lever contacts0.30.41.2-0.7-1.10.30.9-0.00.4-0.50.5-0.80.60.80.80.8-0.40.60.5-0.20.3-0.30.3-0.30.7
Pavlov. Cond. magazine entry number0.20.20.9-0.20.2-0.0-0.20.90.2-0.30.30.90.20.10.5-0.9-0.4-0.10.2-0.80.3-0.30.50.8-0.5
Pavlov. Cond. intertrial magazine entries1.72.67.1-1.4-1.90.60.82.30.8-1.81.80.81.91.42.20.1-2.10.91.4-2.71.8-1.81.81.60.1
Pavlov. Cond. lever-magazine prob. diff.0.20.31.6-0.2-0.50.10.4-0.7-0.10.0-0.0-1.3-0.00.1-0.11.00.20.0-0.10.5-0.20.2-0.4-1.10.8
Pavlov. Cond. response bias0.30.43.2-0.3-1.2-0.20.20.1-0.2-0.30.3-1.00.40.20.21.8-0.80.30.1-0.30.7-0.7-0.1-0.51.1
Time in closed arm before self-admin1.21.53.6-1.6-1.31.81.6-0.41.6-1.21.2-0.51.61.71.4-0.2-0.21.91.50.20.3-0.41.70.1-0.1
Time in closed arm after self-admin0.40.41.4-1.1-0.80.80.6-0.60.6-0.70.7-1.20.60.60.90.30.10.30.6-0.3-0.10.10.6-0.20.0
Time in open arm before self-admin1.81.94.81.82.2-1.6-1.60.2-1.21.6-1.61.4-1.9-1.6-1.3-1.11.0-1.5-1.50.7-1.11.1-1.70.3-0.5
Time in open arm after self-admin0.20.20.70.80.4-0.7-0.40.4-0.50.5-0.50.6-0.5-0.4-0.80.0-0.1-0.3-0.60.40.2-0.1-0.50.30.3
Bone: periosteal estimation0.20.51.40.80.3-0.9-1.20.8-0.90.2-0.20.90.1-0.9-0.70.6-0.8-0.6-0.5-0.11.0-1.1-0.30.40.9
Bone: periosteal perimeter0.10.20.6-0.3-0.50.2-0.00.50.2-0.70.70.20.60.20.6-0.2-0.60.20.5-0.60.7-0.80.60.20.3
Bone: post-yield work0.71.13.21.80.7-1.4-1.71.3-1.20.9-0.91.6-0.6-1.3-0.80.7-0.8-0.9-0.7-0.40.9-0.9-0.71.0-0.1
Progressive ratio test 1 active lever presses0.81.05.2-0.80.50.30.4-2.3-0.10.1-0.1-1.40.3-0.2-1.0-0.51.50.1-0.42.0-0.90.9-0.6-1.51.3
Progressive ratio test 1 breakpoint1.01.26.2-0.80.50.20.3-2.5-0.20.2-0.2-1.60.2-0.3-1.2-0.31.6-0.0-0.62.2-1.01.0-0.8-1.71.4
Progressive ratio test 1 inactive lever presses0.30.51.70.11.10.20.1-0.9-0.10.7-0.70.6-0.2-0.1-0.8-1.01.20.3-0.41.3-0.90.9-0.20.20.1
Progressive ratio test 2 active lever presses1.51.78.1-1.00.61.51.6-2.81.20.3-0.3-1.00.20.9-0.2-1.22.31.10.72.2-1.91.90.3-0.7-0.6
Progressive ratio test 2 breakpoint1.41.67.7-1.10.51.41.5-2.81.20.2-0.2-1.10.30.8-0.2-1.02.11.10.72.1-1.81.70.3-0.8-0.4
Progressive ratio test 2 inactive lever presses0.61.04.40.11.3-0.3-0.1-1.5-0.40.9-0.9-0.5-0.6-0.7-1.4-0.61.4-0.2-1.02.1-1.21.2-1.0-1.00.4
Incentive Sensitization - Responses0.50.72.0-1.1-0.11.21.0-1.41.0-0.20.2-0.70.40.80.3-0.41.01.00.80.8-0.90.90.6-0.4-0.8
Incentive Sensitization - Breakpoint0.50.61.4-1.1-0.21.21.0-1.21.0-0.30.3-0.70.40.80.4-0.40.90.90.90.6-0.80.80.6-0.3-0.8
Sum of active levers in priming session hrs 5-61.81.77.1-0.3-0.8-1.3-1.20.2-1.3-0.40.4-1.80.3-1.3-1.22.1-1.2-1.3-1.0-0.51.3-1.3-1.2-2.02.7
Progressive ratio0.10.21.9-0.10.40.2-0.10.30.6-0.20.20.60.20.30.6-1.40.20.10.7-0.3-0.20.20.30.4-0.7
Food seeking constrained by brief footshock1.92.36.8-2.1-1.80.40.01.60.7-2.32.3-1.02.00.61.5-0.4-1.80.31.0-2.61.9-1.91.0-0.61.7
Seeking ratio, punishment vs. effort0.40.52.2-1.1-1.10.40.4-0.40.1-0.80.8-1.50.70.10.00.9-0.40.3-0.0-0.50.4-0.40.2-1.21.2
Retroperitoneal fat weight0.72.89.70.8-1.5-1.1-1.42.4-1.0-0.40.41.30.9-0.40.12.6-3.1-0.00.4-2.43.1-3.10.31.81.1
Reaction time number correct0.91.74.52.11.3-2.1-1.51.7-1.81.1-1.12.0-1.0-1.1-1.0-0.2-0.6-1.8-1.4-0.00.5-0.4-1.11.30.3
Reaction time mean minus median1.33.26.6-2.1-2.01.91.81.02.0-2.42.40.12.62.22.1-1.2-1.21.82.3-1.01.5-1.52.40.90.2
Reaction time mean minus median AUC0.92.34.5-1.3-1.81.11.21.51.3-1.91.90.52.11.71.8-0.4-1.61.31.8-1.41.8-1.81.91.20.3
Reaction time num false alarms0.10.10.4-0.1-0.0-0.2-0.50.5-0.40.0-0.0-0.20.2-0.4-0.10.2-0.3-0.6-0.3-0.60.3-0.3-0.3-0.30.5
Reaction time num false alarms AUC0.20.31.1-0.3-0.4-0.1-0.51.1-0.3-0.30.30.10.6-0.20.20.3-0.9-0.5-0.0-1.10.9-0.90.20.20.5
Reaction time trials correct on left0.91.74.52.11.3-2.1-1.51.7-1.81.1-1.12.0-1.0-1.1-1.0-0.2-0.6-1.8-1.4-0.00.5-0.4-1.11.30.3
Reaction time trials on left0.81.64.22.01.2-2.0-1.41.8-1.70.9-0.92.0-0.9-1.0-0.9-0.3-0.7-1.7-1.3-0.10.6-0.5-1.01.40.3
Reaction time mean2.84.49.6-2.6-2.51.71.51.62.2-3.13.1-0.12.82.22.7-1.4-1.81.62.4-2.02.0-2.02.50.80.5
Reaction time mean AUC2.74.49.1-2.6-2.31.81.61.52.4-3.03.00.22.72.32.8-1.8-1.61.62.4-1.81.8-1.82.51.00.3
Median of all reaction times2.43.47.9-2.4-2.21.51.21.32.0-2.82.8-0.22.31.92.5-1.3-1.61.32.0-1.91.6-1.72.10.60.5
Reaction time omissions2.94.27.5-1.8-2.31.21.12.21.7-2.72.70.92.72.02.2-1.1-2.31.52.2-2.42.5-2.62.51.90.5
Reaction time false alarm rate0.40.51.7-1.3-1.00.90.20.00.5-0.80.8-1.10.90.30.70.6-0.50.30.6-1.00.4-0.50.6-0.70.2
Reaction time premature initiation rate1.92.67.1-0.00.91.92.2-2.41.31.1-1.1-0.2-0.61.4-0.1-1.52.71.40.72.6-2.62.50.50.1-1.9
Reaction time premature initiations0.71.24.30.70.90.91.6-1.10.51.0-1.00.6-0.51.1-0.2-1.31.70.60.22.1-1.61.70.30.7-1.2
Std. dev. reaction times3.26.011.6-2.7-3.02.02.02.02.4-3.43.40.23.42.72.8-1.1-2.32.12.9-2.02.5-2.63.11.40.4
Reaction time trials completed0.81.64.22.01.2-2.0-1.41.8-1.70.9-0.92.0-0.9-1.0-0.9-0.3-0.7-1.7-1.3-0.10.6-0.5-1.01.40.3
Reaction time trials AUC0.81.43.81.91.1-1.9-1.31.8-1.60.8-0.81.9-0.8-0.9-0.8-0.4-0.7-1.7-1.2-0.20.6-0.5-0.91.30.4
Run reversals in cocaine runway, females2.42.47.71.02.10.3-0.0-2.10.31.6-1.60.5-1.8-0.2-0.5-1.42.6-0.3-0.62.0-2.82.8-0.6-0.4-2.0
Run reversals in cocaine runway, males0.30.31.80.10.0-0.5-0.50.8-0.4-0.30.30.50.6-0.2-0.5-0.3-0.7-0.4-0.20.41.0-1.0-0.10.31.4
Latency to leave start box in cocaine runway0.40.41.21.00.8-0.3-0.4-0.1-0.51.1-1.10.8-0.6-0.5-1.00.40.4-0.0-0.60.8-0.30.3-0.40.6-0.6
Latency to leave start box in cocaine runway, F0.30.41.50.30.30.70.5-0.80.50.7-0.70.4-0.10.4-0.30.10.70.60.51.2-0.60.60.40.5-1.0
Latency to leave start box in cocaine runway, M0.50.51.50.80.4-1.0-1.00.7-1.00.5-0.50.4-0.5-0.9-0.70.4-0.4-0.4-1.2-0.20.3-0.3-0.70.20.7
Std. dev. time between licks in bursts0.40.51.80.91.40.0-0.7-0.50.10.9-0.91.1-0.7-0.7-0.6-0.80.9-0.0-0.10.8-0.70.6-0.30.6-1.0
Total sessions with >9 infusions1.11.36.9-1.00.31.41.3-2.61.1-0.00.0-1.10.20.7-0.0-1.21.91.10.51.7-1.61.60.3-0.60.0
Short access day 1 total inactive lever presses0.81.04.00.31.40.50.6-0.90.70.8-0.81.2-0.80.3-0.2-2.01.61.10.11.2-1.51.50.10.7-1.1
Short access day 10 total inactive lever presses0.20.61.31.21.0-1.0-1.10.9-0.70.8-0.81.1-0.8-0.8-0.6-0.40.0-0.5-1.0-0.5-0.00.1-0.71.00.1
Short access day 1 total infusions0.81.16.7-0.50.50.80.8-2.60.60.2-0.2-1.2-0.20.2-0.2-0.71.80.7-0.21.6-1.61.6-0.2-0.80.2
Short access day 10 total infusions1.21.65.1-2.3-0.71.21.3-2.20.9-1.21.2-2.11.50.8-0.0-0.81.01.20.51.2-0.40.40.3-1.71.6
Short access total infusions1.11.47.4-0.80.60.30.4-2.70.10.2-0.2-1.8-0.0-0.2-0.9-0.61.80.2-0.62.1-1.51.4-0.7-1.71.0
Short access day 1 locomotion0.81.03.3-0.00.91.00.9-1.80.70.6-0.60.1-0.40.50.0-1.31.80.80.31.3-1.71.70.2-0.0-0.7
Short access day 10 total locomotion0.20.31.1-0.40.50.10.2-1.0-0.30.5-0.5-0.3-0.2-0.3-0.6-0.20.90.3-0.80.8-0.80.7-0.5-0.60.4
Short access total locomotion0.81.05.7-0.80.50.80.9-2.40.40.3-0.3-1.1-0.20.2-0.3-0.61.80.4-0.11.3-1.61.6-0.2-1.20.2
One hour access (0.3 mA shock)0.81.04.5-1.1-0.20.30.3-2.1-0.20.1-0.1-2.00.1-0.3-0.81.10.90.8-0.51.1-0.70.7-0.6-1.91.1
Compulsive drug intake1.11.25.01.70.4-0.3-0.21.6-0.11.1-1.12.0-1.2-0.20.40.3-0.60.20.2-1.8-0.10.10.32.2-2.1
One hour access (shock baseline)1.52.38.3-2.7-1.41.31.2-2.30.9-1.61.6-2.91.70.90.20.40.61.50.60.9-0.0-0.10.4-2.62.1
Social response proportion1.31.54.12.00.9-1.9-1.81.6-1.30.9-0.91.7-1.3-1.3-0.80.1-0.8-1.3-0.8-1.00.6-0.5-1.01.3-0.5
Social responses1.41.84.61.30.6-2.2-2.10.8-2.00.7-0.70.4-0.7-1.7-1.71.3-0.9-1.6-1.3-0.21.1-1.0-1.6-0.31.9
Social time0.50.72.50.30.3-0.9-0.8-0.7-0.80.4-0.4-1.2-0.7-0.9-0.80.60.4-0.9-1.00.5-0.40.5-1.4-1.61.4
Soleus weight3.811.122.63.83.0-4.5-4.60.2-4.83.8-3.80.6-3.7-4.6-4.23.10.1-4.5-4.51.4-0.30.4-4.3-1.01.8
Bone: stiffness0.61.02.51.1-0.1-1.2-1.61.2-1.30.2-0.20.80.2-1.1-0.81.4-1.4-0.9-0.6-0.71.5-1.5-0.50.31.4
Tibialis anterior weight0.41.34.01.20.1-2.0-1.71.6-1.60.1-0.11.0-0.2-1.2-0.20.7-1.5-1.4-0.9-1.21.4-1.4-0.80.31.2
Time to tail flick, vehicle, before self-admin3.03.18.12.62.8-1.7-1.81.0-1.32.3-2.32.8-2.1-1.5-1.1-1.60.9-1.5-1.70.9-1.11.1-1.22.1-1.4
Time to tail flick, vehicle, after self-admin0.50.61.5-1.1-1.20.20.30.40.5-1.21.2-1.00.80.51.00.4-0.80.50.5-0.80.8-0.80.4-1.10.6
Time to tail flick, test, before self-admin2.22.35.0-1.3-1.80.80.91.71.0-2.12.10.32.21.51.3-0.4-1.71.51.5-1.02.1-2.11.70.81.1
Time to tail flick, test, after self-admin1.01.04.10.90.7-1.6-1.60.5-1.40.5-0.5-0.1-1.0-1.3-1.00.3-0.2-2.0-1.50.40.1-0.1-1.4-0.30.7
Delta time to tail flick, vehicle, before/after SA3.53.49.0-2.6-3.01.21.3-0.21.1-2.62.6-2.72.21.31.41.5-1.51.31.4-1.41.6-1.61.1-2.51.7
Delta time to tail flick, test, before/after SA2.93.06.51.21.7-1.7-1.6-1.5-1.61.8-1.8-1.1-2.4-2.0-1.60.51.5-2.5-2.21.2-1.81.9-2.4-1.7-0.2
Tibia length1.23.39.1-0.5-2.40.20.12.40.4-2.02.00.92.01.01.31.2-3.00.81.5-2.63.0-3.01.81.80.5
Ambulatory time before self-admin0.20.41.4-0.10.4-0.2-0.0-1.1-0.30.2-0.2-1.0-0.3-0.4-0.7-0.20.7-0.4-0.60.4-0.60.6-0.6-1.20.8
Ambulatory time after self-admin0.40.51.8-1.1-0.80.50.6-0.30.3-1.11.1-1.30.90.40.5-0.3-0.20.1-0.2-0.40.3-0.30.3-0.51.2
Bone: tissue strength0.10.10.50.10.10.10.10.30.2-0.10.10.70.30.20.3-0.6-0.10.20.2-0.20.2-0.20.50.6-0.4
Total heroin consumption0.70.92.6-1.6-1.10.60.30.20.4-1.61.6-1.41.20.40.8-0.4-0.5-0.40.4-0.80.6-0.60.5-1.31.0
Bone: trabecular number0.10.21.30.8-0.0-0.3-0.20.4-0.20.4-0.40.8-0.1-0.1-0.10.9-0.50.1-0.1-0.10.3-0.30.21.1-0.7
Bone: trabecular spacing0.20.31.0-0.7-0.60.00.00.20.2-0.90.9-0.30.60.20.5-0.6-0.50.20.4-0.90.7-0.70.2-0.61.0
Bone: trabecular thickness0.30.31.50.80.1-0.8-0.71.2-0.60.0-0.00.90.1-0.20.30.0-0.8-0.8-0.3-0.20.7-0.7-0.00.80.3
Bone: trabecular tissue density0.20.31.20.80.5-0.7-0.90.3-0.80.5-0.50.6-0.3-0.7-1.10.7-0.2-0.3-0.40.30.5-0.5-0.60.10.5
Water consumed over 24 hours0.20.31.30.60.6-0.7-0.40.2-0.60.8-0.80.2-0.3-0.4-0.4-0.00.3-1.1-0.70.4-0.30.4-0.70.2-0.0
Number of responses in last shaping day0.60.62.00.41.1-0.0-0.1-1.4-0.20.7-0.7-0.2-0.7-0.4-0.6-1.01.4-0.4-0.71.1-1.21.2-0.6-0.60.4