Hub : Genes

Capns1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Capns1 0.86 0.03 0.0e+00 0.72 0.73 0.73 0.74 4.0e-53 1.4e-55 1.2e-54 1.1e-55
2 Liver mRNA stability Capns1 0.03 0.02 6.8e-04 0.02 0.02 0.02 0.02 1.6e-03 3.4e-03 1.6e-03 3.7e-03
3 Eye gene expression Capns1 0.45 0.18 4.4e-04 0.06 0.01 0.03 0.04 3.9e-02 2.5e-01 1.2e-01 9.2e-02
4 BLA mRNA stability Capns1 0.11 0.06 3.0e-07 0.14 0.13 0.13 0.14 1.4e-07 1.6e-07 1.8e-07 1.1e-07
5 pVTA gene expression Capns1 0.88 0.07 0.0e+00 0.69 0.67 0.73 0.72 1.5e-75 2.3e-71 1.2e-83 2.7e-81
6 Liver gene expression Capns1 0.32 0.14 0.0e+00 0.27 0.28 0.28 0.28 2.0e-30 2.1e-31 2.7e-31 4.6e-31
7 NAcc mRNA stability Capns1 0.08 0.04 0.0e+00 0.13 0.14 0.13 0.14 1.7e-18 2.8e-20 9.3e-19 7.6e-20
8 LHb gene expression Capns1 0.87 0.07 0.0e+00 0.54 0.11 0.52 -0.01 5.3e-15 1.7e-03 2.2e-14 4.6e-01
9 OFC gene expression Capns1 0.92 0.04 0.0e+00 0.52 0.04 0.53 0.03 1.4e-14 4.0e-02 9.1e-15 5.9e-02
10 PL gene expression Capns1 0.65 0.02 0.0e+00 0.84 0.86 0.85 0.86 7.0e-163 3.9e-172 3.0e-169 1.2e-171
11 PL mRNA stability Capns1 0.16 0.07 0.0e+00 0.23 0.23 0.23 0.23 1.4e-24 1.8e-24 6.5e-25 5.1e-25
12 Brain gene expression Capns1 0.42 0.01 0.0e+00 0.79 0.78 0.8 0.8 1.2e-115 3.2e-114 1.2e-119 2.4e-120
13 NAcc gene expression Capns1 0.66 0.03 0.0e+00 0.82 0.84 0.84 0.84 4.0e-215 1.9e-229 6.1e-229 1.1e-226
14 IC mRNA stability Capns1 0.07 0.05 9.1e-04 0.04 0.03 0 0 8.7e-03 2.8e-02 1.8e-01 2.6e-01
15 IC gene expression Capns1 0.89 0.05 0.0e+00 0.63 0.31 0.7 0.41 1.1e-33 1.0e-13 1.2e-39 1.3e-18
16 Brain mRNA stability Capns1 0.27 0.17 0.0e+00 0.33 0.27 0.34 0.22 1.3e-31 4.5e-25 4.3e-32 1.9e-20
17 Adipose gene expression Capns1 0.04 0.03 2.8e-05 0.02 0.02 0.01 0.02 1.0e-03 1.9e-03 2.4e-02 3.0e-03
18 RMTg gene expression Capns1 0.48 0.15 2.6e-12 0.4 0.36 0.36 0.37 1.3e-11 2.0e-10 2.4e-10 1.2e-10
19 OFC mRNA stability Capns1 0.24 0.16 4.3e-04 0.11 0.07 0.08 0.1 1.7e-03 8.2e-03 5.5e-03 2.8e-03
20 IL gene expression Capns1 0.98 0 0.0e+00 0.59 0.42 0.6 0.06 2.6e-17 2.7e-11 1.3e-17 1.6e-02
21 Adipose mRNA stability Capns1 0.02 0.02 8.6e-03 0.01 0.01 0.01 0.01 3.4e-02 4.5e-02 5.7e-02 6.1e-02
22 IL mRNA stability Capns1 0.38 0.21 1.1e-04 0.07 0.17 0.13 0.09 1.2e-02 8.5e-05 4.3e-04 3.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.61.11.90.90.01.21.21.00.70.81.11.31.01.01.01.01.30.90.81.21.30.51.21.31.4
Area under the delay curve0.60.72.10.81.50.90.70.70.90.90.60.80.70.80.60.71.20.80.90.30.71.10.60.30.1
BMI with tail0.10.20.5-0.2-0.7-0.3-0.4-0.5-0.4-0.3-0.4-0.4-0.6-0.7-0.6-0.5-0.2-0.5-0.4-0.3-0.1-0.4-0.6-0.3-0.7
BMI without tail0.30.92.21.11.30.90.90.91.11.11.00.90.80.70.80.90.70.71.20.80.81.50.70.70.4
Body weight3.214.016.83.93.33.94.03.83.73.63.84.03.73.63.73.74.13.73.44.04.13.23.63.93.7
Weight adjusted by age0.10.10.40.2-0.20.40.00.50.10.0-0.00.30.30.50.20.30.50.6-0.20.40.4-0.50.30.60.4
Bone surface1.52.73.51.80.91.71.81.61.71.71.81.91.61.61.61.61.91.71.51.81.81.21.51.81.6
Bone volume1.62.83.91.70.91.81.71.61.61.61.71.91.61.61.61.62.01.81.52.01.91.11.62.01.8
Breakpoint value in progressive ratio session1.21.44.01.22.01.01.31.01.51.51.11.01.01.01.21.11.10.81.60.81.11.70.80.90.6
Number of licking bursts2.74.35.4-1.8-2.2-1.7-2.0-2.2-2.0-2.0-2.3-2.2-2.2-2.2-2.3-2.2-1.9-1.6-2.3-1.8-1.9-2.3-2.3-1.9-2.3
Context. condit. distance diff. score0.00.00.10.20.10.2-0.1-0.10.20.1-0.1-0.1-0.1-0.1-0.2-0.1-0.20.2-0.10.2-0.20.1-0.40.2-0.4
Locomotion velocity, session 10.60.61.2-0.8-1.1-0.8-0.7-1.0-0.9-0.9-0.7-0.6-0.9-0.9-0.9-0.9-0.6-0.9-0.8-0.5-0.6-0.6-0.7-0.5-0.4
Locomotion distance, session 10.50.61.31.10.80.70.80.50.90.80.80.80.50.50.60.50.70.80.70.90.80.90.31.10.5
Locomotion velocity, session 20.70.81.4-0.8-0.5-1.1-0.9-0.9-0.8-0.8-0.5-0.9-0.8-0.9-0.8-0.8-1.2-1.1-0.6-1.1-1.2-0.6-0.8-1.1-0.9
Locomotion distance, session 21.42.02.9-1.0-1.5-1.6-1.4-1.6-1.2-1.2-1.3-1.4-1.5-1.5-1.5-1.5-1.4-1.4-1.3-1.2-1.4-1.3-1.7-1.3-1.7
Locomotion velocity, session 30.30.30.5-0.6-0.6-0.4-0.7-0.5-0.6-0.6-0.6-0.6-0.5-0.4-0.6-0.5-0.7-0.4-0.6-0.4-0.6-0.5-0.6-0.4-0.4
Locomotion distance, session 33.03.34.82.12.11.61.61.92.22.21.91.51.92.01.91.91.31.92.01.61.42.21.41.61.1
Stereotopy head waving bouts, day 30.60.71.4-1.2-1.1-0.7-0.7-0.9-1.1-1.1-0.7-0.6-0.8-0.8-0.7-0.8-0.6-1.2-0.9-1.1-0.7-1.0-0.4-0.8-0.3
Stereotopy head waving duration, day 31.51.72.9-1.7-1.6-1.1-1.1-1.3-1.6-1.6-1.2-1.0-1.3-1.3-1.2-1.3-1.0-1.6-1.3-1.6-1.0-1.4-0.8-1.3-0.7
Locomotion velocity, session 70.30.40.80.90.40.70.50.50.80.80.70.60.60.60.50.60.50.80.50.70.50.40.30.60.3
Locomotion distance, session 70.20.20.70.50.30.30.30.40.50.50.40.30.40.40.40.40.30.60.40.80.30.40.30.70.5
Stereotopy head waving bouts, day 71.71.92.8-1.2-1.1-1.3-1.4-1.4-1.3-1.3-1.5-1.3-1.5-1.6-1.5-1.5-1.2-1.2-1.5-1.4-1.3-1.3-1.6-1.3-1.7
Stereotopy head waving duration, day 72.32.73.4-1.6-1.4-1.4-1.6-1.7-1.7-1.7-1.7-1.6-1.8-1.8-1.8-1.8-1.5-1.7-1.7-1.7-1.5-1.6-1.7-1.7-1.8
Locomotion velocity, session 83.94.75.7-1.8-2.1-1.9-2.1-2.3-2.0-2.0-2.1-2.2-2.2-2.2-2.3-2.3-2.3-2.0-2.2-1.9-2.2-2.3-2.4-2.1-2.4
Locomotion distance, session 80.71.02.1-0.5-0.8-0.9-1.1-1.1-0.6-0.7-1.0-1.1-1.1-1.1-1.1-1.1-1.2-0.6-1.0-0.6-1.1-0.8-1.5-0.7-1.4
Degree of sensitization distance0.50.61.3-0.9-1.1-0.6-0.6-0.8-0.9-1.0-0.9-0.6-0.8-0.8-0.8-0.8-0.5-0.6-0.9-0.3-0.5-1.1-0.5-0.4-0.1
Degree of sensitization stereotypy1.21.32.6-0.9-0.7-1.0-1.2-1.2-1.0-1.0-1.3-1.1-1.3-1.3-1.3-1.3-1.0-0.9-1.2-1.1-1.0-1.1-1.5-1.0-1.6
Conditioned locomotion0.60.61.2-0.7-0.1-1.0-0.8-0.8-0.6-0.6-0.7-0.7-0.9-0.9-0.8-0.8-0.8-1.0-0.5-1.0-0.8-0.3-0.9-1.0-1.1
Cocaine response after cond. corrected0.10.10.3-0.50.3-0.5-0.2-0.1-0.4-0.4-0.1-0.3-0.1-0.1-0.1-0.1-0.4-0.3-0.1-0.5-0.20.00.2-0.20.2
Cocaine response after cond. not corrected0.10.10.3-0.40.0-0.4-0.10.1-0.4-0.40.1-0.10.10.00.10.1-0.3-0.20.1-0.3-0.20.10.40.00.5
Cocaine response before conditioning1.31.52.11.20.41.21.21.21.21.21.31.31.31.21.31.31.31.21.21.51.31.01.31.41.4
Saline control response0.10.10.3-0.40.2-0.6-0.4-0.3-0.3-0.4-0.2-0.4-0.4-0.5-0.3-0.3-0.5-0.4-0.1-0.3-0.4-0.2-0.2-0.3-0.2
Bone: connectivity density0.30.40.70.7-0.20.70.80.60.50.60.80.80.70.70.70.70.70.50.50.50.70.20.80.60.7
Bone: cortical apparent density1.72.43.9-1.6-2.0-1.6-1.6-1.6-1.5-1.5-1.8-1.6-1.6-1.6-1.6-1.6-1.4-1.4-1.6-1.1-1.4-1.5-1.6-1.1-1.3
Bone: cortical area1.72.53.31.51.81.61.51.71.61.51.61.51.61.61.61.61.41.71.61.81.31.51.71.61.7
Bone: cortical porosity0.91.02.1-0.6-1.3-0.8-0.8-0.9-0.8-0.7-0.8-0.8-0.8-0.8-0.9-0.8-0.8-0.7-1.1-1.3-0.9-1.5-1.0-1.2-1.4
Bone: cortical porosity1.51.63.1-0.8-1.5-1.2-1.1-1.2-1.1-1.0-1.1-1.1-1.1-1.1-1.2-1.2-1.1-1.0-1.3-1.5-1.2-1.7-1.4-1.5-1.8
Bone: cortical thickness0.61.01.60.81.31.10.91.10.90.80.90.91.01.01.01.00.91.01.01.20.81.01.21.01.2
Bone: cortical thickness0.60.70.9-1.0-0.6-0.9-0.8-0.9-0.9-0.9-0.9-0.8-0.9-1.0-0.9-0.9-0.9-0.8-0.9-0.7-0.8-0.8-0.8-0.8-0.7
Bone: cortical tissue density2.02.74.4-1.6-2.1-1.7-1.7-1.7-1.6-1.6-1.9-1.7-1.7-1.7-1.7-1.7-1.5-1.5-1.7-1.2-1.5-1.6-1.7-1.2-1.5
Condit. Reinf. active minus inactive responses0.20.20.4-0.5-0.6-0.3-0.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.7-0.4-0.6-0.3-0.3-0.4-0.6-0.5
Condit. Reinf. active-inactive response ratio0.20.20.5-0.7-0.3-0.0-0.2-0.3-0.6-0.6-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.7-0.2-0.7-0.2-0.20.1-0.7-0.2
Condit. Reinf. active responses2.32.83.6-1.5-1.7-1.6-1.6-1.9-1.6-1.5-1.7-1.7-1.8-1.8-1.8-1.8-1.6-1.8-1.5-1.8-1.6-1.3-1.9-1.7-1.9
Condit. Reinf. inactive responses2.63.25.1-1.3-1.7-2.0-1.9-2.0-1.4-1.4-1.8-1.9-1.9-1.9-1.9-1.9-1.8-1.7-1.6-1.6-1.8-1.4-2.3-1.6-2.2
Incentive salience index mean0.20.20.4-0.4-0.5-0.3-0.3-0.5-0.4-0.4-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.7-0.3-0.7-0.4-0.1-0.5-0.6-0.7
Condit. Reinf. lever presses0.00.00.20.2-0.0-0.00.1-0.00.10.10.1-0.2-0.00.00.0-0.0-0.3-0.20.2-0.4-0.20.4-0.1-0.3-0.4
Condit. Reinf. active minus inactive responses1.31.74.01.32.01.21.31.41.41.41.51.11.41.51.41.40.80.91.60.90.81.61.30.81.1
Condit. Reinf. active-inactive response ratio0.10.10.5-0.30.7-0.2-0.2-0.2-0.2-0.3-0.3-0.4-0.3-0.2-0.3-0.3-0.6-0.3-0.1-0.2-0.50.0-0.2-0.4-0.2
Condit. Reinf. active responses3.54.96.42.32.52.22.22.32.32.42.52.12.32.42.42.31.81.92.51.81.82.52.21.71.9
Condit. Reinf. inactive responses4.35.67.22.72.02.22.32.52.62.72.72.42.62.52.62.62.12.32.51.92.12.42.31.91.8
Condit. Reinf. lever presses8.011.114.03.33.73.63.53.43.43.33.53.43.43.43.43.43.13.03.52.93.13.43.32.93.1
Condit. Reinf. lever reinforcers received3.95.47.22.52.72.42.42.42.52.52.52.22.42.52.42.41.92.12.52.01.92.52.21.91.9
Conditioned reinforcement - actives0.61.01.7-1.2-0.7-1.1-1.1-1.1-1.1-1.1-1.3-1.1-1.1-1.0-1.1-1.1-0.8-0.9-1.0-0.8-0.8-1.0-1.0-0.8-0.8
Conditioned reinforcement - inactives0.10.20.60.80.80.20.40.30.70.70.30.20.30.40.30.3-0.10.30.4-0.10.10.4-0.1-0.1-0.6
Conditioned locomotion2.63.44.0-1.7-1.9-1.9-1.8-2.0-1.8-1.8-1.9-1.9-1.9-1.8-1.9-1.9-1.8-1.9-1.7-1.8-1.8-1.8-1.9-1.8-1.8
Patch foraging indifference point 0 sec0.10.20.60.40.40.20.20.50.40.50.60.30.60.80.60.60.20.30.4-0.20.30.30.5-0.00.2
Patch foraging indifference point AUC0.60.91.5-0.9-0.8-0.8-0.9-0.9-1.0-1.0-0.6-0.8-0.8-1.0-1.0-0.9-1.0-1.0-1.0-1.0-1.1-1.1-0.9-1.2-0.9
Delay disc. indifference point, 0s delay0.30.41.90.91.40.10.2-0.10.80.80.00.2-0.1-0.1-0.1-0.10.70.30.70.50.61.0-0.50.5-0.5
Delay disc. indifference point, 16s delay1.01.14.10.82.01.00.81.01.31.30.70.81.01.01.01.01.20.91.40.30.71.61.00.20.2
Delay disc. indifference point, 2s delay1.01.12.51.31.60.90.80.91.31.20.91.00.91.00.90.91.41.21.01.11.11.00.61.00.5
Delay disc. indifference point, 24s delay2.22.53.21.51.61.61.61.71.71.71.71.61.71.71.71.71.61.61.61.11.31.81.61.11.1
Delay disc. indifference point, 4s delay0.10.10.60.20.80.30.1-0.00.20.10.00.10.00.1-0.1-0.10.40.10.2-0.3-0.00.3-0.1-0.3-0.5
Delay disc. indifference point, 8s delay0.20.30.90.50.30.90.60.50.40.40.40.70.50.60.40.50.90.70.40.30.40.50.60.20.3
Indifference point function ln k0.20.40.90.50.70.40.50.60.70.70.30.40.50.60.60.50.60.60.80.70.61.00.50.50.6
Indifference point function log k0.20.40.90.50.70.40.50.60.70.70.30.40.50.60.60.50.60.60.80.70.61.00.50.50.6
Patch foraging total patch changes 0 sec0.20.30.80.50.50.30.30.60.50.60.80.40.70.90.70.70.30.50.5-0.10.40.50.60.10.4
Patch foraging total patch changes 12 sec0.10.10.5-0.10.5-0.1-0.10.1-0.1-0.10.40.10.20.20.10.2-0.2-0.20.2-0.7-0.10.20.3-0.5-0.0
Patch foraging total patch changes 18 sec0.10.10.6-0.1-0.6-0.2-0.4-0.2-0.3-0.2-0.0-0.2-0.1-0.1-0.2-0.2-0.4-0.0-0.6-0.3-0.4-0.8-0.3-0.2-0.3
Patch foraging total patch changes 24 sec0.50.91.51.21.01.00.81.01.00.91.01.00.90.90.80.90.91.20.70.91.00.70.71.10.7
Patch foraging total patch changes 6 sec0.10.10.40.10.2-0.1-0.00.30.00.00.60.10.40.40.30.4-0.20.1-0.0-0.4-0.2-0.30.4-0.30.2
Patch foraging time to switch 0 sec0.40.81.3-1.1-0.7-1.0-0.9-0.9-1.0-1.0-1.0-1.0-0.9-1.0-0.8-0.9-0.9-1.0-0.5-1.1-1.0-0.2-0.6-1.0-0.7
Patch foraging water rate 0 sec0.40.92.3-0.7-1.1-0.9-0.9-0.9-0.9-0.8-0.7-0.9-0.8-0.8-0.8-0.8-1.1-0.7-1.2-1.0-1.1-1.5-0.9-1.0-0.9
Patch foraging water rate 12 sec0.51.01.71.01.01.31.01.11.00.90.81.10.91.00.90.91.21.30.41.21.20.40.61.30.8
Patch foraging water rate 18 sec0.10.10.8-0.2-0.2-0.2-0.2-0.2-0.4-0.4-0.4-0.1-0.4-0.3-0.3-0.3-0.1-0.2-0.6-0.3-0.1-0.9-0.4-0.5-0.3
Patch foraging water rate 24 sec0.10.10.50.40.3-0.0-0.1-0.10.30.3-0.1-0.1-0.1-0.1-0.1-0.10.20.4-0.30.20.1-0.6-0.5-0.1-0.7
Patch foraging water rate 6 sec1.01.42.71.50.61.21.31.31.31.31.11.31.21.31.21.21.41.60.81.31.30.40.91.20.8
Seeking ratio, delayed vs. immediate footshock1.31.63.11.51.51.31.01.21.51.41.31.21.21.21.11.11.41.81.21.41.41.20.81.40.7
Distance traveled before self-admin0.10.21.80.41.3-0.10.2-0.20.50.5-0.1-0.0-0.1-0.10.0-0.10.2-0.10.70.20.10.9-0.20.2-0.1
Distance traveled after self-admin2.12.63.11.71.51.71.71.51.71.71.71.71.71.61.71.71.61.41.61.61.41.51.61.61.6
Extensor digitorum longus weight0.20.61.2-1.0-0.8-0.7-0.8-0.8-1.0-1.1-0.8-0.6-0.9-0.9-0.9-0.9-0.5-0.7-0.9-0.3-0.5-1.0-0.6-0.4-0.2
Bone: elastic displacement0.00.00.1-0.20.0-0.0-0.00.1-0.1-0.1-0.10.10.00.10.10.10.1-0.0-0.10.20.1-0.10.20.10.3
Bone: elastic work1.92.53.21.51.61.61.61.61.51.51.51.71.51.61.61.61.81.51.61.61.71.51.61.71.6
Bone: endosteal estimation1.63.54.32.01.71.81.91.81.91.92.12.01.91.91.91.91.81.81.91.91.71.71.81.71.8
Bone: endosteal perimeter1.32.73.51.81.91.51.61.61.91.91.71.61.61.61.71.71.41.61.91.71.31.91.41.41.4
Epididymis fat weight0.00.10.5-0.0-0.70.20.10.0-0.1-0.1-0.20.2-0.1-0.1-0.1-0.10.50.1-0.30.50.5-0.4-0.00.40.2
Delta time in closed arm before/after self-admin1.31.21.71.30.61.31.21.21.01.01.31.21.11.21.11.11.21.20.81.11.20.71.11.01.1
Delta time in open arm before/after self-admin0.40.41.0-0.8-0.5-1.0-0.8-0.3-0.8-0.8-0.5-0.8-0.5-0.5-0.4-0.4-0.6-0.4-0.8-0.7-0.6-0.8-0.3-0.5-0.4
Diff in mean of infusions in LGA sessions0.60.71.6-0.40.2-1.1-0.6-1.0-0.4-0.4-0.8-0.9-0.8-0.9-0.7-0.8-1.1-1.1-0.2-1.1-1.00.0-0.9-1.1-1.3
Delay discount exponential model param0.70.82.1-0.9-1.4-1.1-0.9-0.9-1.0-1.0-0.8-0.9-0.9-0.9-0.8-0.8-1.3-1.0-1.0-0.4-0.8-1.1-0.8-0.3-0.3
Extinction: sum of active levers before priming3.53.85.51.61.22.12.11.81.91.91.92.01.81.91.91.92.01.72.12.12.12.32.02.22.3
Active lever presses in extinction session 61.31.32.90.71.11.11.41.01.01.01.11.11.01.01.21.11.10.61.51.01.01.41.51.11.7
Bone: final force2.03.14.11.71.52.01.91.81.71.71.81.91.81.81.71.81.91.91.71.61.71.51.81.91.7
Bone: final moment2.64.14.82.01.82.22.12.12.02.02.02.12.12.12.02.12.12.12.02.01.91.82.12.22.1
Food consumed during 24 hour testing period0.60.91.51.20.91.21.00.91.11.20.91.01.01.00.91.00.91.01.00.80.80.80.70.60.4
Glucose0.20.40.8-0.9-0.7-0.2-0.6-0.7-0.8-0.9-0.6-0.4-0.7-0.7-0.7-0.7-0.3-0.6-0.7-0.2-0.4-0.8-0.4-0.4-0.1
Heart weight0.10.21.00.51.00.40.40.50.40.40.20.40.30.20.40.40.30.40.30.10.20.30.30.1-0.1
Delay discount hyperbolic model param0.50.61.7-0.7-1.3-0.9-0.7-0.7-0.9-0.8-0.6-0.8-0.7-0.8-0.6-0.7-1.2-0.8-0.8-0.3-0.7-0.9-0.6-0.3-0.1
Intermittent access intake day 1-15 change1.32.64.11.71.31.61.61.61.61.51.51.61.51.61.51.61.92.01.22.02.00.91.42.01.7
Intermittent access intake escalation0.91.93.51.40.91.31.31.41.21.21.21.31.31.41.31.31.71.80.91.81.90.61.21.81.6
Intermittent access intake escalation 21.41.52.11.11.41.41.41.21.21.11.01.21.21.31.21.21.21.31.21.31.31.11.31.21.4
Intermitt. access day 1 inactive lever presses1.65.99.22.72.22.52.62.62.72.82.72.52.62.72.62.62.02.12.91.71.73.02.31.71.6
Intermitt. access day 15 inactive lever presses0.61.32.11.41.11.21.11.31.41.41.21.11.31.41.21.30.81.31.20.60.81.31.00.60.3
Intermitt. access escalation Index0.10.20.5-0.10.2-0.6-0.5-0.4-0.1-0.2-0.5-0.5-0.5-0.5-0.5-0.5-0.1-0.2-0.3-0.2-0.3-0.3-0.7-0.2-0.7
Intermittent access day 1 total infusions1.72.84.8-1.3-1.0-1.8-1.9-2.0-1.3-1.4-1.9-1.9-1.9-2.0-1.9-1.9-1.5-1.3-1.5-1.3-1.4-1.2-2.2-1.3-2.2
Intermittent access day 15 total infusions0.10.10.4-0.00.3-0.4-0.5-0.40.1-0.0-0.5-0.4-0.4-0.4-0.5-0.40.30.3-0.30.30.4-0.2-0.70.3-0.5
Intermittent access terminal intake (last 3 days)0.30.41.1-0.30.5-0.7-0.7-0.8-0.2-0.3-0.9-0.8-0.7-0.7-0.8-0.7-0.4-0.1-0.4-0.3-0.2-0.2-1.0-0.3-1.1
Intermittent access total infusions0.60.71.7-0.6-0.2-1.0-1.1-1.1-0.5-0.6-1.1-1.1-1.0-1.0-1.1-1.0-0.5-0.4-0.8-0.4-0.4-0.6-1.3-0.5-1.2
Intermittent access day 1 locomotion1.01.23.6-0.5-0.5-1.3-1.1-1.3-0.6-0.6-1.0-1.2-1.2-1.2-1.2-1.2-1.2-1.0-0.7-1.1-1.2-0.5-1.6-1.1-1.9
Intermittent access day 15 total locomotion0.00.10.40.3-0.2-0.3-0.1-0.40.20.3-0.2-0.3-0.2-0.2-0.2-0.2-0.10.1-0.10.1-0.0-0.2-0.60.1-0.6
Intermittent access total locomotion1.21.52.8-0.8-1.0-1.4-1.2-1.5-0.9-0.9-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.1-1.0-1.0-1.1-0.9-1.6-1.1-1.7
Intermittent access standard deviation2.24.65.82.32.42.22.12.12.42.42.02.12.12.12.12.12.02.22.32.22.32.21.92.21.7
Left kidney weight2.210.213.83.02.23.33.13.32.92.93.13.43.23.33.23.23.73.42.63.73.72.33.23.63.6
Right kidney weight2.712.316.63.12.73.63.33.53.23.23.43.73.53.43.43.54.13.53.24.04.03.03.63.94.0
Cocaine induced anxiety0.00.00.10.00.1-0.00.10.0-0.0-0.00.20.20.0-0.00.10.00.0-0.10.0-0.00.10.10.1-0.00.1
Post-drug Anxiety0.10.10.4-0.20.6-0.1-0.1-0.1-0.0-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.40.1-0.5-0.40.3-0.1-0.6-0.5
Baseline Anxiety0.00.10.10.20.30.40.10.30.30.30.10.10.20.30.20.20.10.10.2-0.2-0.20.20.1-0.3-0.4
Tail length5.220.322.84.54.84.74.74.64.54.54.54.64.54.44.54.54.44.54.54.64.34.34.44.44.4
Length with tail7.432.035.55.75.75.86.05.85.65.55.75.95.75.75.85.75.95.65.45.65.75.05.65.55.5
Length without tail3.310.813.23.42.93.43.63.43.13.13.33.53.33.33.33.33.63.52.73.53.52.33.23.33.4
Times rat made contact with spout0.60.71.7-1.1-1.3-0.1-0.6-1.0-1.1-1.1-1.1-0.8-1.0-0.9-1.0-1.0-0.4-0.6-1.2-0.1-0.3-1.2-0.6-0.4-0.2
Lifetime Intake0.81.01.8-0.9-0.6-1.2-1.3-1.3-0.8-0.8-1.3-1.2-1.2-1.2-1.2-1.2-0.8-0.5-1.0-0.5-0.6-0.8-1.4-0.6-1.2
Liver weight, left0.50.81.2-1.1-0.7-0.8-1.0-0.9-1.0-1.0-1.0-0.9-0.9-1.0-0.9-0.9-0.9-0.8-1.0-0.8-0.8-0.9-0.8-0.9-0.7
Liver weight, right0.30.61.1-1.0-0.2-0.8-0.7-0.6-0.8-0.9-0.7-0.7-0.7-0.8-0.7-0.7-0.9-0.9-0.7-0.8-0.9-0.6-0.4-0.9-0.5
Locomotor activity0.50.81.7-1.3-1.3-0.8-0.8-0.8-1.2-1.1-0.6-0.7-0.8-0.8-0.7-0.7-0.8-1.3-0.8-0.9-0.7-1.1-0.4-0.7-0.2
Locomotor testing distance0.61.22.7-1.3-1.6-1.1-1.2-1.1-1.3-1.3-0.9-0.9-1.1-1.1-1.0-1.0-0.9-1.2-1.1-0.9-0.8-1.2-0.8-0.7-0.5
Locomotor testing rearing1.63.14.5-1.8-1.8-1.9-2.0-1.7-1.9-2.0-1.8-1.7-1.9-1.8-1.9-1.8-1.6-1.4-2.1-1.3-1.6-2.1-1.7-1.1-1.3
Locomotion in novel chamber0.30.31.2-0.6-0.4-0.6-0.4-0.6-0.4-0.3-0.3-0.5-0.5-0.5-0.3-0.5-0.8-1.10.1-0.9-0.80.2-0.3-1.0-0.5
Locomotion in novel chamber post-restriction0.10.21.20.01.1-0.10.1-0.30.20.10.0-0.0-0.1-0.2-0.1-0.1-0.2-0.30.7-0.7-0.41.10.0-0.5-0.4
Fecal boli incidents, locomotor time 12.63.86.6-2.0-1.4-2.0-1.9-2.0-1.8-1.7-1.9-2.0-2.0-1.8-1.8-1.9-2.3-2.6-1.4-2.3-2.2-1.3-1.6-2.3-1.9
Change in fecal boli incidents, locomotor task0.10.10.3-0.0-0.10.30.40.3-0.2-0.20.20.30.30.20.30.2-0.0-0.20.1-0.1-0.10.10.4-0.20.6
Time >=10cm from walls, locomotor time 10.00.00.2-0.3-0.00.2-0.10.0-0.1-0.2-0.30.0-0.00.2-0.1-0.0-0.3-0.2-0.0-0.2-0.40.10.1-0.2-0.1
Bouts of movement, locomotor time 10.70.84.21.22.10.80.70.61.21.20.60.60.50.50.60.60.50.81.00.80.71.10.30.80.0
Total resting periods, locomotor time 10.60.64.11.02.00.70.60.51.11.10.40.50.40.40.50.50.40.51.00.60.61.20.20.6-0.1
Rest time, locomotor task time 11.72.14.7-1.3-0.3-1.3-1.0-1.6-1.2-1.2-1.4-1.3-1.6-1.6-1.5-1.6-1.5-2.2-0.8-1.9-1.5-0.6-1.4-1.9-1.8
Distance moved, locomotor task time 10.10.10.70.1-0.3-0.1-0.20.20.10.10.1-0.10.20.10.20.20.20.8-0.20.60.2-0.30.00.50.3
Vertical activity count, locomotor time 11.12.64.71.90.81.51.51.81.51.51.81.51.81.81.81.71.52.21.21.61.41.01.41.61.5
Time >=10cm from walls, locomotor time 21.11.73.1-1.2-0.3-1.2-1.3-1.3-1.1-1.1-1.4-1.3-1.2-1.3-1.3-1.2-1.7-1.5-0.9-1.6-1.7-0.8-1.2-1.6-1.5
Bouts of movement, locomotor time 20.00.10.80.10.90.20.2-0.10.10.0-0.5-0.0-0.2-0.2-0.1-0.20.30.00.10.20.00.1-0.20.1-0.1
Total resting periods, locomotor time 20.00.10.4-0.10.60.00.0-0.2-0.1-0.1-0.5-0.2-0.3-0.3-0.2-0.30.0-0.2-0.1-0.1-0.2-0.0-0.3-0.1-0.2
Rest time, locomotor task time 20.30.41.3-0.60.0-0.4-0.2-0.6-0.6-0.6-0.4-0.5-0.7-0.7-0.6-0.7-0.7-1.0-0.4-1.1-0.7-0.3-0.6-1.0-0.8
Distance moved, locomotor task time 20.10.10.6-0.1-0.5-0.5-0.6-0.2-0.2-0.3-0.3-0.3-0.2-0.4-0.3-0.30.00.5-0.60.20.1-0.8-0.40.1-0.2
Vertical activity count, locomotor time 20.71.02.01.20.70.90.91.11.01.01.01.01.11.01.01.01.01.40.81.11.00.70.80.90.8
Light reinforcement 10.10.10.5-0.2-0.4-0.4-0.3-0.2-0.3-0.3-0.3-0.3-0.2-0.2-0.3-0.3-0.3-0.2-0.6-0.2-0.3-0.7-0.4-0.5-0.4
Light reinforcement 22.33.64.9-1.9-2.2-1.8-1.8-1.8-1.9-1.9-1.8-1.9-1.8-1.8-1.8-1.8-1.9-2.2-1.9-1.9-1.8-2.1-1.8-2.1-1.8
Bone: marrow area1.63.64.52.01.71.81.91.91.92.02.12.01.91.92.01.91.81.82.01.91.71.71.91.71.8
Bone: maximum diameter1.42.73.11.71.81.61.61.71.71.71.61.61.71.71.71.71.51.71.61.81.41.51.61.51.6
Bone: maximum force3.15.56.42.32.22.52.42.42.32.32.32.52.42.32.32.42.52.52.32.32.42.12.42.42.3
Bone: maximum moment3.76.57.42.62.52.72.62.62.52.52.52.62.62.52.52.62.62.72.52.52.52.32.52.62.5
Mean time between licks in bursts0.00.10.20.40.3-0.3-0.00.40.30.30.30.20.30.40.30.3-0.00.30.2-0.3-0.10.30.10.1-0.2
Mean num. licks in bursts1.11.73.30.91.11.51.41.21.11.01.21.31.21.31.31.21.41.01.31.51.41.21.51.51.8
Cd content in liver0.20.20.9-0.4-0.8-0.1-0.3-0.4-0.5-0.4-0.5-0.3-0.4-0.4-0.4-0.4-0.1-0.4-0.6-0.2-0.1-1.0-0.4-0.2-0.2
Co content in liver0.40.50.9-0.7-1.0-0.7-0.5-0.6-0.8-0.8-0.3-0.6-0.6-0.6-0.6-0.6-0.8-0.9-0.7-0.8-0.8-0.6-0.4-0.8-0.5
Cu content in liver1.21.42.01.41.21.11.31.11.21.11.31.31.21.11.11.11.31.31.01.31.30.61.11.31.1
Fe content in liver0.30.40.8-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.9-0.5-0.9-0.6-0.4-0.5-0.8-0.6
K content in liver0.10.10.30.30.5-0.00.30.50.20.30.40.30.50.40.40.40.00.10.4-0.2-0.00.50.5-0.10.2
Mg content in liver0.40.41.2-0.8-0.2-0.8-0.6-0.3-0.8-0.8-0.4-0.6-0.4-0.4-0.4-0.4-0.8-0.8-0.5-1.1-0.9-0.5-0.1-1.1-0.4
Mn content in liver0.60.61.1-1.0-0.7-0.9-0.6-0.7-1.0-0.9-0.6-0.7-0.6-0.6-0.6-0.6-0.9-1.1-0.7-1.1-1.0-0.8-0.3-1.0-0.4
Na content in liver0.91.01.61.11.30.70.91.11.01.00.90.91.01.01.01.00.81.11.00.90.81.20.91.00.9
Rb content in liver0.10.10.4-0.2-0.0-0.3-0.3-0.3-0.2-0.2-0.4-0.4-0.2-0.3-0.3-0.3-0.3-0.4-0.2-0.5-0.3-0.1-0.4-0.4-0.6
Se content in liver5.66.68.1-2.8-2.7-2.5-2.3-2.5-2.8-2.8-2.5-2.6-2.4-2.4-2.4-2.4-2.7-2.9-2.5-2.8-2.8-2.6-2.0-2.8-2.1
Sr content in liver0.20.20.5-0.4-0.7-0.4-0.3-0.4-0.6-0.5-0.1-0.3-0.4-0.4-0.3-0.4-0.5-0.5-0.4-0.6-0.5-0.4-0.2-0.6-0.2
Zn content in liver2.12.44.2-1.5-2.0-1.4-1.3-1.4-1.8-1.8-1.1-1.3-1.3-1.4-1.4-1.4-1.5-1.5-1.7-1.8-1.5-2.0-1.1-1.7-1.2
Bone: minimum diameter3.46.39.62.93.12.32.42.62.82.82.62.42.52.52.52.52.22.62.72.42.02.62.22.32.0
Time in familiar zone, hab. session 10.40.41.20.40.60.70.50.50.40.30.60.60.50.50.60.50.50.60.50.90.50.50.70.81.1
Time in novel zone, hab. session 11.21.22.7-0.9-0.6-1.0-1.1-0.9-0.9-0.9-1.1-1.1-1.0-0.9-1.0-1.0-1.0-0.9-1.0-1.6-1.0-1.0-1.1-1.5-1.7
Total zone transitions, hab. session 10.00.10.30.20.2-0.2-0.1-0.30.10.1-0.1-0.1-0.3-0.4-0.3-0.3-0.1-0.1-0.00.1-0.10.3-0.50.0-0.5
Total locomotion distance, hab. session 11.11.63.71.41.91.01.31.11.41.41.31.31.11.11.21.21.21.01.50.71.11.81.11.00.8
Locomotion velocity, hab. session 10.60.92.01.01.30.71.00.81.01.01.11.00.80.81.00.90.90.61.20.50.91.40.90.90.7
Time in familiar zone, hab. session 22.02.13.31.31.71.31.51.61.31.41.81.41.71.61.71.71.11.01.70.91.11.61.80.81.5
Time in novel zone, hab. session 21.31.32.1-1.1-1.3-1.0-1.2-1.3-1.1-1.2-1.4-1.1-1.3-1.2-1.4-1.3-0.8-0.9-1.3-0.8-0.8-1.2-1.3-0.8-1.1
Total zone transitions, hab. session 23.14.05.1-1.7-1.5-2.2-1.9-2.1-1.9-1.9-1.9-2.0-2.1-2.1-2.1-2.1-2.0-2.0-1.9-2.1-2.0-1.7-2.2-2.0-2.3
Total locomotion distance, hab. session 20.10.10.70.00.2-0.4-0.1-0.4-0.2-0.1-0.1-0.2-0.4-0.5-0.3-0.4-0.2-0.4-0.2-0.8-0.2-0.1-0.5-0.5-0.8
Locomotion velocity, hab. session 20.20.20.8-0.1-0.1-0.5-0.3-0.5-0.3-0.3-0.2-0.3-0.5-0.6-0.4-0.5-0.4-0.5-0.3-0.9-0.4-0.3-0.6-0.6-0.8
Novel to familiar place preference ratio0.20.20.50.40.60.30.40.60.50.40.40.40.50.50.50.50.50.70.30.40.40.10.50.00.3
Novelty place preference0.10.10.40.40.40.20.20.50.40.30.30.30.40.30.40.40.30.60.20.30.3-0.00.30.00.2
Time in novel zone, NPP test0.00.00.20.20.2-0.00.00.20.10.10.00.00.10.10.10.10.10.4-0.00.20.1-0.20.1-0.2-0.0
Total zone transitions, NPP test0.10.10.3-0.1-0.5-0.4-0.3-0.6-0.3-0.3-0.3-0.3-0.5-0.5-0.5-0.5-0.3-0.5-0.3-0.0-0.2-0.3-0.6-0.0-0.3
Total locomotion distance, NPP test2.43.33.71.91.91.81.91.71.81.81.91.91.71.71.81.71.91.61.91.71.91.81.71.81.8
Locomotion velocity, NPP test2.63.64.11.92.01.92.01.81.91.92.02.01.91.81.91.92.01.62.01.72.02.01.91.81.9
Intraocular pressure0.10.10.3-0.1-0.1-0.3-0.3-0.30.00.0-0.3-0.4-0.3-0.3-0.1-0.3-0.5-0.4-0.0-0.2-0.50.0-0.4-0.1-0.4
Delta distance traveled before/after self-admin2.62.74.31.70.51.81.61.81.41.42.11.81.81.81.81.81.51.81.11.71.61.01.81.61.8
Delta ambulatory time before/after self-admin2.22.74.31.80.41.81.71.81.41.52.11.91.81.81.81.81.71.91.01.71.70.71.71.71.8
Parametrial fat weight0.10.30.9-0.9-0.9-0.2-0.3-0.1-0.9-0.9-0.2-0.1-0.2-0.1-0.2-0.2-0.6-0.7-0.7-0.6-0.6-0.80.3-0.60.5
Pavlov. Cond. lever latency0.10.10.40.20.10.30.20.30.20.20.10.40.20.20.20.20.60.40.20.60.50.10.30.50.5
Pavlov. Cond. magazine entry latency0.70.91.3-1.0-0.6-0.8-0.8-1.0-1.0-1.1-1.0-0.9-1.0-0.9-1.0-1.0-0.8-0.9-1.0-1.1-0.8-1.0-0.8-0.9-0.9
Pavlov. Cond. change in total contacts0.40.41.2-0.2-0.2-0.5-0.4-0.6-0.4-0.4-0.4-0.7-0.6-0.6-0.7-0.6-0.8-0.6-0.5-0.9-0.8-0.2-0.8-0.9-1.1
Pavlov. Cond. index score0.50.61.1-0.7-0.6-0.7-0.5-0.8-0.8-0.8-0.6-0.8-0.7-0.7-0.8-0.8-0.8-0.8-0.8-1.1-0.8-0.7-0.7-0.9-0.8
Pavlov. Cond. latency score0.20.30.8-0.4-0.3-0.6-0.4-0.5-0.5-0.5-0.4-0.6-0.5-0.4-0.5-0.5-0.7-0.6-0.5-0.9-0.7-0.3-0.5-0.7-0.7
Pavlov. Cond. lever contacts0.00.10.20.20.50.00.20.20.20.20.3-0.10.20.30.20.2-0.4-0.00.3-0.3-0.30.30.1-0.2-0.2
Pavlov. Cond. magazine entry number0.50.60.90.80.50.60.60.80.80.90.80.80.80.80.90.90.70.70.91.00.70.80.80.80.9
Pavlov. Cond. intertrial magazine entries0.91.11.7-1.0-0.9-1.1-1.1-1.1-0.9-0.9-1.0-1.1-1.1-1.1-1.0-1.1-1.3-1.3-0.8-0.8-1.3-0.5-1.1-1.1-0.9
Pavlov. Cond. lever-magazine prob. diff.0.70.91.6-0.9-0.7-0.8-0.7-0.9-1.0-1.0-0.8-1.0-0.9-0.9-1.0-1.0-1.0-1.0-1.0-1.3-1.0-0.9-0.8-1.1-1.0
Pavlov. Cond. response bias0.30.40.6-0.7-0.3-0.4-0.4-0.6-0.7-0.7-0.6-0.6-0.6-0.5-0.6-0.6-0.6-0.7-0.6-0.8-0.6-0.6-0.4-0.7-0.5
Pavlov. Cond. lever latency5.67.69.7-2.8-2.7-3.1-3.0-2.8-2.8-2.8-2.8-2.8-2.8-2.8-2.8-2.8-2.7-2.7-2.7-2.5-2.8-2.6-2.6-2.4-2.4
Pavlov. Cond. magazine entry latency3.84.55.62.22.22.32.42.22.22.22.22.22.22.22.22.22.11.92.31.72.12.22.11.71.8
Pavlov. Cond. change in total contacts7.712.313.93.73.73.73.63.63.73.73.33.53.53.63.53.53.53.63.53.43.63.53.23.33.0
Pavlov. Cond. index score6.38.511.13.02.93.33.23.03.03.02.93.02.93.02.92.93.02.82.92.73.02.82.82.62.6
Pavlov. Cond. latency score5.67.59.72.82.73.13.02.82.82.82.72.82.82.82.82.82.72.62.82.42.82.62.72.32.3
Pavlov. Cond. lever contacts5.98.210.73.02.93.33.12.92.92.92.82.92.82.92.82.82.92.82.82.72.92.82.72.62.4
Pavlov. Cond. magazine entry number4.65.67.3-2.3-2.2-2.7-2.6-2.4-2.4-2.3-2.2-2.5-2.3-2.3-2.3-2.3-2.6-2.3-2.3-2.4-2.7-2.2-2.3-2.3-2.2
Pavlov. Cond. intertrial magazine entries1.11.73.5-1.1-1.9-1.4-1.4-1.3-1.3-1.3-1.1-1.2-1.1-1.2-1.2-1.2-1.4-1.0-1.4-1.0-1.5-1.7-1.2-1.1-1.1
Pavlov. Cond. lever-magazine prob. diff.6.08.010.32.82.83.23.12.92.82.82.72.92.82.92.82.82.92.72.82.73.02.62.82.52.5
Pavlov. Cond. response bias7.09.612.13.23.13.53.33.23.23.23.03.13.13.13.03.13.23.13.03.03.23.02.92.92.7
Time in closed arm before self-admin1.51.93.0-1.4-0.4-1.4-1.7-1.5-1.2-1.3-1.6-1.5-1.5-1.5-1.6-1.5-1.3-1.0-1.3-1.2-1.3-1.0-1.6-1.2-1.7
Time in closed arm after self-admin0.20.21.40.51.20.20.0-0.00.60.50.10.20.00.00.0-0.00.2-0.10.7-0.10.11.0-0.2-0.1-0.5
Time in open arm before self-admin4.54.97.32.21.02.72.72.32.02.12.32.52.42.52.42.32.01.82.22.11.91.92.51.92.5
Time in open arm after self-admin1.01.12.30.90.11.01.11.30.70.71.21.01.31.31.21.31.01.20.61.01.00.41.41.11.5
Bone: periosteal estimation2.34.95.82.32.32.22.22.32.32.22.32.32.32.22.22.22.12.32.22.42.02.02.22.22.3
Bone: periosteal perimeter1.32.34.41.42.11.41.41.51.61.61.51.41.51.51.51.51.21.31.81.61.11.91.51.31.5
Bone: post-yield work2.23.24.52.11.81.71.81.82.02.11.91.81.81.81.81.81.82.01.81.71.71.61.51.61.3
Progressive ratio test 1 active lever presses0.00.10.20.30.0-0.1-0.1-0.30.20.2-0.2-0.1-0.2-0.3-0.2-0.20.10.2-0.00.20.20.3-0.50.2-0.4
Progressive ratio test 1 breakpoint0.10.10.20.40.2-0.0-0.0-0.30.30.3-0.1-0.1-0.1-0.2-0.1-0.10.10.30.10.30.30.5-0.40.2-0.4
Progressive ratio test 1 inactive lever presses0.10.20.80.90.70.10.30.20.80.90.30.20.30.30.20.20.00.40.50.20.10.7-0.30.1-0.7
Progressive ratio test 2 active lever presses0.40.51.2-0.6-0.3-0.8-0.8-1.0-0.4-0.5-1.1-0.8-0.9-0.9-0.9-0.9-0.3-0.3-0.5-0.1-0.2-0.2-1.0-0.1-0.6
Progressive ratio test 2 breakpoint0.60.61.5-0.7-0.5-0.9-1.0-1.1-0.6-0.6-1.2-1.0-1.0-1.0-1.0-1.0-0.5-0.5-0.6-0.2-0.3-0.3-1.1-0.2-0.8
Progressive ratio test 2 inactive lever presses0.30.41.90.81.40.30.30.21.11.10.20.20.30.30.30.30.00.31.10.30.21.4-0.20.3-0.5
Incentive Sensitization - Responses0.70.92.0-1.0-0.6-1.1-1.2-1.2-0.8-0.8-1.4-1.2-1.2-1.1-1.2-1.1-0.8-0.7-0.8-0.4-0.7-0.5-1.2-0.4-0.9
Incentive Sensitization - Breakpoint0.70.91.9-1.0-0.6-1.1-1.2-1.2-0.7-0.8-1.4-1.1-1.2-1.1-1.1-1.1-0.8-0.6-0.8-0.4-0.6-0.6-1.2-0.4-0.8
Sum of active levers in priming session hrs 5-60.10.10.3-0.3-0.5-0.4-0.3-0.5-0.2-0.2-0.4-0.4-0.4-0.5-0.3-0.3-0.4-0.5-0.0-0.2-0.40.0-0.4-0.1-0.2
Progressive ratio0.00.00.20.1-0.1-0.10.0-0.1-0.00.00.20.0-0.0-0.10.0-0.0-0.3-0.30.2-0.4-0.30.20.0-0.4-0.3
Food seeking constrained by brief footshock2.63.24.51.91.91.92.01.71.91.92.01.91.81.91.91.81.51.42.01.41.52.11.81.41.5
Seeking ratio, punishment vs. effort0.40.61.30.71.10.90.80.70.90.80.70.70.80.80.70.70.80.90.70.70.70.70.60.80.6
Retroperitoneal fat weight0.52.24.8-2.2-1.9-1.2-1.2-1.2-2.1-2.1-1.2-1.1-1.3-1.3-1.2-1.3-1.4-1.9-1.7-1.3-1.3-2.0-0.5-1.4-0.0
Reaction time number correct0.00.10.50.0-0.70.10.1-0.0-0.2-0.20.00.1-0.1-0.1-0.1-0.10.00.1-0.50.10.0-0.5-0.10.20.1
Reaction time mean minus median0.20.61.00.60.10.70.60.90.60.60.90.81.00.90.80.90.81.00.50.80.70.20.90.90.9
Reaction time mean minus median AUC0.61.42.31.00.11.21.11.30.90.91.31.31.41.41.31.31.31.50.61.31.20.21.31.31.5
Reaction time num false alarms0.91.33.0-1.3-1.4-1.2-1.4-0.9-1.1-1.1-1.3-1.2-1.1-0.9-1.1-1.0-0.9-0.8-1.3-1.0-0.8-1.7-1.1-0.7-1.0
Reaction time num false alarms AUC1.11.73.4-1.5-1.8-1.3-1.5-1.1-1.3-1.3-1.4-1.3-1.2-1.0-1.2-1.2-1.1-1.2-1.5-1.2-1.0-1.9-1.2-0.9-1.1
Reaction time trials correct on left0.00.10.50.0-0.70.10.1-0.0-0.2-0.20.00.1-0.1-0.1-0.1-0.10.00.1-0.50.10.0-0.5-0.10.20.1
Reaction time trials on left0.00.10.50.0-0.70.10.10.0-0.2-0.20.00.1-0.1-0.1-0.0-0.10.00.1-0.50.10.0-0.5-0.10.30.2
Reaction time mean0.20.30.80.3-0.60.50.40.50.30.30.30.50.50.50.40.50.70.70.10.90.6-0.10.40.90.6
Reaction time mean AUC0.10.20.90.2-0.90.50.30.40.20.20.30.40.40.50.40.40.60.5-0.00.70.5-0.20.40.80.6
Median of all reaction times0.10.11.0-0.0-1.00.2-0.00.0-0.1-0.0-0.20.1-0.00.0-0.00.00.30.2-0.30.50.2-0.4-0.10.50.2
Reaction time omissions0.10.10.9-0.3-0.8-0.3-0.20.1-0.3-0.30.10.00.10.20.10.10.20.2-0.50.10.1-0.90.20.20.4
Reaction time false alarm rate0.70.91.6-1.1-1.0-1.1-1.3-0.9-0.9-0.9-1.1-1.1-0.9-0.8-1.0-0.9-0.9-0.9-0.9-0.9-0.7-1.2-1.0-0.8-1.0
Reaction time premature initiation rate0.10.10.30.50.50.10.30.10.30.40.50.30.20.20.30.20.2-0.00.2-0.20.30.3-0.1-0.2-0.4
Reaction time premature initiations0.00.00.20.50.00.00.20.10.10.20.50.30.10.10.20.10.1-0.0-0.1-0.20.2-0.1-0.2-0.1-0.3
Std. dev. reaction times0.51.01.90.9-0.11.00.81.00.80.80.91.01.11.00.91.01.21.40.51.41.20.20.91.41.1
Reaction time trials completed0.00.10.50.0-0.70.10.10.0-0.2-0.20.00.1-0.1-0.1-0.0-0.10.00.1-0.50.10.0-0.5-0.10.30.2
Reaction time trials AUC0.10.10.8-0.2-0.9-0.1-0.0-0.1-0.4-0.4-0.1-0.0-0.2-0.2-0.2-0.2-0.1-0.0-0.6-0.0-0.1-0.7-0.10.20.2
Run reversals in cocaine runway, females0.80.81.60.90.10.80.80.90.80.90.90.80.90.90.90.91.11.20.41.31.10.10.61.20.8
Run reversals in cocaine runway, males0.20.21.5-0.7-1.20.20.00.1-0.8-0.7-0.20.10.10.10.10.1-0.1-0.3-0.4-0.5-0.1-0.30.7-0.30.7
Latency to leave start box in cocaine runway0.20.20.90.7-0.00.20.40.40.50.50.50.40.40.30.30.30.60.80.10.80.80.1-0.00.90.2
Latency to leave start box in cocaine runway, F0.10.10.30.3-0.50.10.10.20.10.10.10.00.10.10.00.10.20.5-0.40.30.3-0.5-0.20.3-0.2
Latency to leave start box in cocaine runway, M0.10.10.40.30.4-0.2-0.00.00.30.20.30.0-0.0-0.1-0.00.00.40.30.20.50.50.3-0.20.70.1
Std. dev. time between licks in bursts0.30.51.51.01.2-0.10.40.80.80.80.90.50.70.70.70.7-0.00.40.9-0.5-0.21.00.3-0.2-0.4
Total sessions with >9 infusions1.31.63.3-1.3-1.8-1.3-1.3-1.4-1.4-1.4-1.3-1.3-1.3-1.3-1.3-1.3-1.1-1.0-1.4-0.8-1.0-1.3-1.2-0.9-0.9
Short access day 1 total inactive lever presses0.40.61.81.31.30.20.50.51.21.20.60.50.50.40.50.50.60.70.80.70.61.0-0.10.7-0.4
Short access day 10 total inactive lever presses1.43.47.02.22.71.41.71.72.42.41.81.51.81.81.81.81.21.52.41.41.32.61.21.50.8
Short access day 1 total infusions0.00.10.30.00.3-0.4-0.3-0.2-0.0-0.1-0.1-0.3-0.1-0.2-0.2-0.2-0.50.0-0.1-0.0-0.4-0.0-0.3-0.1-0.3
Short access day 10 total infusions0.50.61.1-0.8-1.0-0.8-1.0-1.0-0.7-0.7-0.9-0.8-0.9-0.9-0.9-0.9-0.5-0.4-0.7-0.3-0.4-0.5-0.9-0.4-0.6
Short access total infusions0.91.11.5-1.1-1.1-1.2-1.2-1.2-1.1-1.1-1.2-1.1-1.1-1.1-1.2-1.2-1.0-0.8-1.1-0.7-0.9-1.0-1.1-0.7-0.9
Short access day 1 locomotion1.01.34.3-0.9-2.1-1.0-1.0-1.0-1.2-1.1-1.1-1.0-1.0-0.9-1.0-1.0-1.2-1.0-1.4-0.8-1.0-1.6-1.1-0.9-0.9
Short access day 10 total locomotion0.30.51.91.00.30.50.60.50.91.00.90.50.70.70.70.60.30.31.20.20.31.40.40.2-0.0
Short access total locomotion1.21.52.1-1.0-1.5-1.2-1.2-1.3-1.1-1.1-1.0-1.2-1.2-1.1-1.2-1.2-1.3-1.3-1.0-1.2-1.3-1.0-1.3-1.3-1.4
One hour access (0.3 mA shock)0.50.51.31.01.10.60.50.41.01.00.40.50.50.60.50.50.91.10.70.90.90.80.10.80.1
Compulsive drug intake0.10.11.30.51.1-0.10.10.30.40.30.20.10.10.20.20.2-0.00.2-0.0-0.1-0.1-0.1-0.1-0.1-0.4
One hour access (shock baseline)0.00.10.2-0.00.2-0.0-0.2-0.40.20.1-0.4-0.2-0.2-0.3-0.3-0.30.40.30.20.30.40.4-0.40.3-0.3
Social response proportion1.92.24.21.52.11.41.41.41.71.71.51.31.51.51.61.51.11.11.91.01.22.01.41.01.1
Social responses0.60.71.41.00.80.60.80.90.91.11.20.71.11.01.11.10.20.21.20.00.31.10.90.20.5
Social time2.53.44.92.11.61.71.71.82.12.11.81.61.92.01.91.91.71.82.01.71.82.21.51.81.5
Soleus weight0.00.10.5-0.2-0.6-0.2-0.1-0.3-0.4-0.40.0-0.1-0.3-0.3-0.3-0.3-0.2-0.2-0.5-0.3-0.3-0.7-0.1-0.3-0.1
Bone: stiffness1.52.53.01.61.71.71.61.51.61.61.61.71.61.51.51.61.71.71.61.41.61.51.51.61.4
Tibialis anterior weight0.10.20.6-0.6-0.4-0.4-0.4-0.4-0.7-0.7-0.4-0.2-0.5-0.5-0.5-0.5-0.2-0.3-0.60.2-0.2-0.6-0.20.10.3
Time to tail flick, vehicle, before self-admin0.40.41.2-0.7-1.1-0.5-0.7-0.6-0.6-0.6-0.6-0.6-0.5-0.4-0.6-0.5-0.4-0.5-0.7-0.5-0.4-0.8-0.6-0.4-0.5
Time to tail flick, vehicle, after self-admin0.30.52.40.41.50.40.70.40.70.80.40.40.50.40.60.50.4-0.11.3-0.00.21.50.5-0.00.2
Time to tail flick, test, before self-admin0.20.20.70.0-0.6-0.1-0.5-0.30.0-0.0-0.4-0.2-0.3-0.2-0.5-0.30.50.5-0.60.40.6-0.9-0.70.5-0.4
Time to tail flick, test, after self-admin0.10.10.5-0.3-0.1-0.2-0.2-0.4-0.3-0.2-0.6-0.3-0.4-0.4-0.3-0.4-0.4-0.7-0.2-0.5-0.4-0.3-0.4-0.5-0.4
Delta time to tail flick, vehicle, before/after SA0.90.81.41.01.20.91.10.91.01.00.91.00.90.91.00.90.90.61.10.50.71.11.00.40.7
Delta time to tail flick, test, before/after SA0.50.51.7-0.7-0.0-0.5-0.2-0.5-0.7-0.7-0.5-0.5-0.5-0.5-0.3-0.5-1.2-1.3-0.2-1.1-1.3-0.1-0.1-1.3-0.3
Tibia length2.77.410.42.72.13.02.92.72.62.62.63.02.62.62.52.63.22.72.53.13.22.42.52.82.7
Ambulatory time before self-admin0.20.22.10.51.40.00.30.00.70.60.10.20.10.10.20.10.1-0.10.80.1-0.01.00.00.1-0.1
Ambulatory time after self-admin4.24.96.12.42.02.22.52.12.42.42.42.42.32.22.42.32.22.02.22.12.12.02.12.12.0
Bone: tissue strength3.53.64.72.11.92.01.92.02.02.01.91.92.02.01.91.91.92.21.81.61.81.61.71.71.4
Total heroin consumption0.30.30.70.70.60.40.50.30.80.90.40.40.50.40.50.50.80.40.80.50.80.60.20.70.1
Bone: trabecular number1.42.33.31.50.61.81.71.51.41.41.51.71.51.51.41.51.81.51.31.51.81.01.51.71.5
Bone: trabecular spacing0.30.51.70.41.30.40.60.80.60.50.70.50.70.80.80.80.40.50.70.30.50.70.90.50.7
Bone: trabecular thickness0.10.10.5-0.2-0.7-0.1-0.2-0.2-0.3-0.3-0.4-0.1-0.4-0.4-0.4-0.40.10.0-0.50.30.1-0.5-0.30.2-0.1
Bone: trabecular tissue density1.92.74.7-2.2-1.8-1.4-1.7-1.8-2.0-2.0-1.9-1.6-1.8-1.8-1.8-1.8-1.4-1.7-1.7-1.1-1.4-1.7-1.3-1.2-0.7
Water consumed over 24 hours0.40.61.40.60.31.20.90.70.60.70.70.80.70.70.70.70.90.70.71.00.90.60.80.70.9
Number of responses in last shaping day0.10.11.00.51.0-0.00.10.10.40.40.10.20.20.10.10.10.20.20.50.50.40.5-0.10.50.1