Hub : Genes

Capns1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Capns1 0.03 0.02 2.5e-04 0.03 0.02 0.03 0.02 7.5e-04 1.2e-03 8.4e-04 1.0e-03
2 LHb gene expression Capns1 0.8 0.06 0.0e+00 0.47 0.09 0.52 0 1.4e-12 3.6e-03 2.0e-14 2.8e-01
3 PL gene expression Capns1 0.65 0.02 0.0e+00 0.86 0.86 0.86 0.86 1.9e-173 7.4e-176 5.8e-177 9.9e-178
4 BLA mRNA stability Capns1 0.08 0.05 8.1e-06 0.1 0.09 0.08 0.09 4.5e-06 2.1e-05 4.2e-05 2.8e-05
5 BLA gene expression Capns1 0.87 0.03 0.0e+00 0.73 0.76 0.75 0.76 2.0e-55 6.4e-60 2.9e-58 1.5e-59
6 Liver gene expression Capns1 0.32 0.14 0.0e+00 0.28 0.28 0.28 0.28 5.5e-31 8.3e-32 2.3e-31 2.4e-31
7 pVTA gene expression Capns1 0.8 0.08 0.0e+00 0.62 0.64 0.64 0.64 7.4e-34 5.2e-35 9.6e-36 2.7e-35
8 IL gene expression Capns1 0.91 0.01 0.0e+00 0.52 0.44 0.57 0.46 1.9e-14 6.6e-12 1.4e-16 2.0e-12
9 NAcc mRNA stability Capns1 0.07 0.04 1.6e-12 0.11 0.1 0.11 0.11 2.5e-12 3.9e-12 5.1e-13 1.4e-12
10 NAcc gene expression Capns1 0.69 0.03 0.0e+00 0.78 0.82 0.83 0.83 2.0e-144 3.3e-163 9.2e-167 2.2e-164
11 Eye gene expression Capns1 0.41 0.17 4.5e-04 0.07 -0 0.03 0.03 2.8e-02 3.6e-01 1.3e-01 1.1e-01
12 PL mRNA stability Capns1 0.15 0.07 0.0e+00 0.22 0.22 0.21 0.22 3.9e-24 1.4e-23 3.7e-23 1.6e-23
13 OFC gene expression Capns1 0.91 0.01 0.0e+00 0.5 -0 0.5 0 7.2e-14 3.6e-01 7.6e-14 2.6e-01
14 OFC mRNA stability Capns1 0.24 0.17 1.1e-03 0.1 0.06 0.1 0.04 2.2e-03 1.3e-02 2.3e-03 4.3e-02
15 Brain gene expression Capns1 0.51 0.02 0.0e+00 0.8 0.74 0.81 0.81 8.0e-121 4.6e-102 1.6e-124 8.3e-123
16 Brain mRNA stability Capns1 0.19 0.09 0.0e+00 0.3 0.27 0.3 0.29 2.3e-28 6.9e-25 1.0e-27 4.9e-27
17 RMTg gene expression Capns1 0.49 0.15 3.4e-12 0.36 0.31 0.29 0.32 1.3e-10 6.5e-09 1.8e-08 2.6e-09
18 Adipose gene expression Capns1 0.05 0.04 1.1e-06 0.04 0.03 0.02 0.03 7.1e-05 1.7e-04 2.3e-03 2.1e-04
19 IL mRNA stability Capns1 0.24 0.16 7.5e-04 0.08 0.12 0.09 0.05 5.9e-03 7.9e-04 2.9e-03 2.3e-02
20 Adipose mRNA stability Capns1 0.02 0.02 8.1e-03 0.01 0 0 0 3.2e-02 7.2e-02 1.3e-01 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.61.01.70.2-1.01.0-1.10.80.7-1.0-1.0-1.0-1.0-1.3-1.0-1.1-1.1-1.0-0.8-1.3-1.21.3-1.1
Area under the delay curve0.40.41.9-1.4-0.50.5-0.60.70.8-0.5-0.5-0.6-0.5-0.8-0.6-0.7-0.7-0.6-0.7-0.6-0.10.2-0.1
BMI with tail0.20.82.01.40.9-0.80.6-0.8-0.90.80.90.90.90.90.90.80.80.81.10.50.6-1.00.9
BMI without tail0.10.10.5-0.6-0.50.4-0.70.40.2-0.4-0.5-0.3-0.3-0.3-0.2-0.3-0.3-0.5-0.3-0.4-0.10.3-0.1
Body weight2.711.214.5-3.0-3.53.4-3.53.33.2-3.3-3.4-3.2-3.3-3.3-3.2-3.3-3.3-3.3-3.0-3.6-3.83.5-3.4
Weight adjusted by age0.20.20.40.5-0.60.3-0.10.30.0-0.3-0.2-0.1-0.3-0.6-0.5-0.6-0.60.00.6-0.4-0.50.3-0.7
Bone surface1.62.83.4-0.7-1.61.7-1.81.61.7-1.7-1.6-1.7-1.7-1.8-1.6-1.7-1.7-1.7-1.7-1.8-1.81.7-1.6
Bone volume1.52.63.7-0.7-1.61.6-1.61.51.5-1.6-1.5-1.6-1.6-1.8-1.5-1.6-1.6-1.6-1.5-1.8-1.91.7-1.7
Breakpoint value in progressive ratio session1.51.75.7-2.4-0.81.2-1.41.31.7-1.1-1.2-1.3-1.1-1.1-1.0-1.2-1.2-1.4-1.9-1.0-0.70.9-0.9
Number of licking bursts3.33.85.22.02.0-2.12.2-1.9-1.92.12.22.12.11.52.11.51.52.22.31.71.7-2.21.7
Context. condit. distance diff. score0.00.00.10.00.3-0.20.2-0.10.10.20.30.20.20.10.20.00.00.20.10.2-0.1-0.30.0
Locomotion velocity, session 10.70.71.31.11.1-0.90.8-1.1-1.01.00.91.01.00.61.00.80.80.80.70.70.5-0.50.5
Locomotion distance, session 10.40.51.1-0.7-0.40.6-0.90.70.9-0.5-0.5-0.6-0.6-1.0-0.5-0.8-0.8-0.7-0.8-0.7-1.00.6-1.0
Locomotion velocity, session 20.60.71.30.50.9-0.70.5-0.8-0.80.80.70.70.81.00.80.90.90.50.51.11.1-0.71.1
Locomotion distance, session 21.42.02.51.61.6-1.41.2-1.3-1.21.51.51.41.41.31.51.51.51.31.21.41.2-1.61.5
Locomotion velocity, session 30.30.30.80.70.4-0.50.7-0.5-0.60.50.50.50.50.50.50.50.50.60.70.70.4-0.50.9
Locomotion distance, session 32.72.94.4-2.0-1.81.8-1.62.02.1-1.8-1.7-1.9-1.8-1.4-1.9-1.6-1.6-1.7-1.8-1.2-1.61.3-1.2
Stereotopy head waving bouts, day 30.60.71.41.10.7-0.70.7-1.0-1.20.70.70.80.80.80.80.70.70.60.80.61.1-0.50.9
Stereotopy head waving duration, day 31.31.62.71.51.2-1.21.2-1.5-1.61.21.21.31.31.11.31.11.11.21.20.91.6-0.91.4
Locomotion velocity, session 70.20.30.5-0.3-0.40.5-0.70.60.7-0.4-0.4-0.4-0.5-0.4-0.5-0.5-0.5-0.6-0.5-0.4-0.70.3-0.6
Locomotion distance, session 70.10.10.5-0.2-0.30.4-0.30.30.4-0.3-0.3-0.3-0.4-0.1-0.3-0.2-0.2-0.3-0.3-0.1-0.70.4-0.5
Stereotopy head waving bouts, day 71.01.11.70.51.1-1.11.1-1.0-0.91.21.21.21.21.01.21.01.01.11.00.71.1-1.31.0
Stereotopy head waving duration, day 72.42.93.31.31.8-1.81.6-1.7-1.71.81.81.81.81.61.81.61.61.71.71.41.8-1.81.7
Locomotion velocity, session 83.94.75.72.32.3-2.22.1-2.1-2.02.32.42.22.22.02.21.91.92.22.12.32.0-2.42.2
Locomotion distance, session 80.71.11.90.91.2-1.01.0-0.9-0.71.11.21.01.01.01.10.90.91.11.01.20.7-1.41.0
Degree of sensitization distance0.50.51.11.00.7-0.70.7-0.9-0.90.70.70.80.80.60.90.70.70.70.80.50.4-0.40.2
Degree of sensitization stereotypy1.31.42.20.61.2-1.21.2-1.0-1.01.31.31.21.21.11.31.21.21.31.20.91.1-1.51.1
Conditioned locomotion0.70.81.20.21.0-1.00.9-0.8-0.71.00.90.91.01.01.01.11.10.90.50.81.1-1.00.8
Cocaine response after cond. corrected0.10.10.2-0.20.0-0.10.2-0.3-0.40.1-0.10.10.10.40.10.40.40.10.20.40.50.10.4
Cocaine response after cond. not corrected0.10.10.2-0.0-0.20.1-0.0-0.2-0.4-0.2-0.3-0.1-0.10.3-0.10.40.4-0.20.00.30.30.40.4
Cocaine response before conditioning1.31.62.0-0.4-1.31.4-1.31.31.2-1.4-1.3-1.4-1.4-1.3-1.3-1.2-1.2-1.3-1.3-1.4-1.31.4-1.1
Saline control response0.00.00.2-0.50.1-0.1-0.2-0.1-0.00.0-0.10.00.00.30.10.40.4-0.1-0.10.20.00.20.0
Bone: connectivity density0.30.50.70.4-0.70.8-0.80.60.5-0.7-0.6-0.7-0.7-0.8-0.7-0.7-0.7-0.8-0.6-0.7-0.60.7-0.5
Bone: cortical apparent density2.22.93.81.91.8-1.71.9-1.7-1.61.71.81.71.71.81.81.71.71.91.71.71.3-1.71.5
Bone: cortical area1.42.12.5-1.5-1.61.6-1.41.41.4-1.5-1.6-1.5-1.5-1.4-1.5-1.4-1.4-1.4-1.4-1.1-1.51.5-1.3
Bone: cortical porosity1.31.52.61.61.1-1.01.1-1.0-1.11.11.31.01.11.11.01.11.11.21.21.11.6-1.61.5
Bone: cortical porosity1.92.03.21.81.3-1.31.3-1.2-1.31.31.61.31.31.31.31.31.31.41.41.41.7-1.81.6
Bone: cortical thickness0.30.50.8-0.9-0.80.7-0.60.60.5-0.7-0.8-0.7-0.7-0.7-0.7-0.8-0.8-0.6-0.7-0.4-0.70.8-0.4
Bone: cortical thickness0.80.91.21.00.9-0.90.9-1.0-1.10.90.91.01.00.80.91.01.00.91.00.90.8-0.70.8
Bone: cortical tissue density2.63.44.32.11.9-1.92.0-1.8-1.71.91.91.81.81.91.91.81.82.01.81.81.4-1.81.6
Condit. Reinf. active minus inactive responses0.20.20.50.60.5-0.50.5-0.5-0.50.50.50.50.50.30.50.50.50.50.40.40.7-0.50.7
Condit. Reinf. active-inactive response ratio0.10.10.70.40.2-0.30.4-0.4-0.60.30.20.30.30.10.30.30.30.30.40.30.8-0.20.7
Condit. Reinf. active responses2.43.03.81.81.9-1.81.6-1.7-1.61.81.81.81.81.61.81.81.81.61.41.61.8-1.81.9
Condit. Reinf. inactive responses2.83.34.61.62.1-1.91.7-1.7-1.41.92.01.81.91.91.91.91.91.71.41.81.5-2.01.8
Incentive salience index mean0.20.20.60.50.5-0.40.4-0.4-0.40.40.40.40.40.30.40.50.50.40.30.50.8-0.60.8
Condit. Reinf. lever presses0.00.00.20.00.00.2-0.20.20.2-0.1-0.1-0.2-0.1-0.1-0.1-0.0-0.0-0.2-0.30.10.4-0.20.4
Condit. Reinf. active minus inactive responses1.62.04.3-2.1-1.51.6-1.61.51.5-1.5-1.6-1.5-1.4-1.1-1.5-1.2-1.2-1.7-1.6-0.9-1.01.3-0.6
Condit. Reinf. active-inactive response ratio0.10.10.5-0.70.1-0.10.2-0.2-0.10.20.10.20.20.30.20.20.20.10.20.50.1-0.20.6
Condit. Reinf. active responses3.85.26.6-2.6-2.32.5-2.52.42.4-2.4-2.4-2.4-2.4-2.0-2.4-2.1-2.1-2.5-2.4-1.9-1.92.1-1.6
Condit. Reinf. inactive responses4.75.87.2-2.1-2.52.6-2.72.72.6-2.6-2.4-2.6-2.6-2.3-2.5-2.3-2.3-2.6-2.5-2.2-1.92.1-2.1
Condit. Reinf. lever presses8.010.913.5-3.7-3.33.4-3.43.33.3-3.3-3.4-3.3-3.3-3.4-3.3-3.4-3.4-3.4-3.4-3.1-2.93.3-2.7
Condit. Reinf. lever reinforcers received3.95.57.2-2.7-2.42.5-2.52.52.5-2.4-2.4-2.4-2.4-2.2-2.4-2.2-2.2-2.5-2.5-2.0-2.12.1-1.8
Conditioned reinforcement - actives0.20.20.4-0.10.4-0.40.6-0.4-0.30.50.40.40.40.40.40.40.40.50.20.30.3-0.40.3
Conditioned reinforcement - inactives0.50.61.7-1.3-0.70.7-0.81.01.1-0.7-0.5-0.8-0.7-0.8-0.6-0.8-0.8-0.7-0.9-0.5-0.40.1-0.4
Conditioned locomotion2.53.03.91.52.0-1.81.7-1.6-1.51.82.01.71.81.71.71.71.71.71.31.81.6-1.91.6
Patch foraging indifference point 0 sec0.10.20.6-0.4-0.70.5-0.50.50.4-0.5-0.4-0.5-0.5-0.3-0.8-0.3-0.3-0.5-0.6-0.20.00.30.2
Patch foraging indifference point AUC0.30.40.70.90.5-0.50.4-0.7-0.80.60.50.60.60.50.60.60.60.50.30.70.7-0.60.8
Delay disc. indifference point, 0s delay0.20.21.7-1.30.5-0.2-0.30.10.60.30.10.10.2-0.20.20.10.1-0.1-0.7-0.4-0.3-0.4-0.3
Delay disc. indifference point, 16s delay1.01.03.9-2.0-0.91.0-0.71.11.2-1.0-1.0-1.1-1.0-1.1-1.0-1.1-1.1-0.9-1.3-0.7-0.20.5-0.1
Delay disc. indifference point, 2s delay0.80.92.5-1.6-0.80.8-1.11.11.2-0.8-0.8-0.8-0.8-0.9-0.8-0.9-0.9-0.9-0.9-1.1-1.10.6-1.0
Delay disc. indifference point, 24s delay2.62.63.3-1.6-1.71.7-1.61.81.7-1.7-1.6-1.7-1.7-1.6-1.7-1.8-1.8-1.6-1.4-1.4-1.11.3-1.1
Delay disc. indifference point, 4s delay0.10.10.4-0.70.2-0.10.0-0.10.00.20.20.10.2-0.20.1-0.0-0.00.00.10.10.5-0.50.5
Delay disc. indifference point, 8s delay0.30.30.5-0.3-0.60.6-0.60.50.5-0.6-0.4-0.5-0.5-0.7-0.6-0.7-0.7-0.5-0.4-0.6-0.30.3-0.2
Indifference point function ln k0.30.40.9-0.9-0.50.6-0.50.70.8-0.6-0.6-0.6-0.6-0.4-0.6-0.6-0.6-0.6-0.7-0.6-0.70.7-0.6
Indifference point function log k0.30.40.9-0.9-0.50.6-0.50.70.8-0.6-0.6-0.6-0.6-0.4-0.6-0.6-0.6-0.6-0.7-0.6-0.70.7-0.6
Patch foraging total patch changes 0 sec0.20.40.9-0.6-0.90.7-0.70.70.6-0.7-0.6-0.7-0.7-0.4-1.0-0.4-0.4-0.7-0.7-0.4-0.20.4-0.0
Patch foraging total patch changes 12 sec0.10.10.3-0.5-0.20.1-0.20.0-0.0-0.2-0.2-0.2-0.1-0.2-0.30.00.0-0.3-0.60.10.60.00.4
Patch foraging total patch changes 18 sec0.00.00.20.5-0.10.1-0.00.0-0.0-0.00.10.00.0-0.0-0.10.10.10.10.10.1-0.1-0.2-0.1
Patch foraging total patch changes 24 sec0.91.11.5-1.0-1.11.0-1.11.11.1-1.0-0.9-0.9-1.0-1.2-1.1-1.1-1.1-0.9-1.0-1.1-1.10.8-1.1
Patch foraging total patch changes 6 sec0.10.10.5-0.1-0.70.5-0.60.40.1-0.5-0.3-0.4-0.4-0.1-0.50.00.0-0.4-0.10.10.20.20.3
Patch foraging time to switch 0 sec0.50.81.30.61.0-0.90.9-1.0-1.00.80.70.80.81.00.91.01.00.70.71.01.2-0.70.9
Patch foraging water rate 0 sec0.60.91.31.10.7-0.80.7-0.8-1.00.91.11.01.01.00.80.90.90.91.11.11.0-1.11.1
Patch foraging water rate 12 sec0.71.01.7-1.1-1.21.0-0.71.11.0-0.9-0.8-0.8-0.9-1.1-0.9-1.3-1.3-0.6-0.3-1.3-1.30.7-1.2
Patch foraging water rate 18 sec0.10.20.50.20.2-0.40.2-0.3-0.40.40.50.50.50.30.30.20.20.40.70.10.5-0.40.7
Patch foraging water rate 24 sec0.00.10.2-0.40.00.00.00.30.40.10.30.10.10.00.1-0.0-0.00.20.4-0.3-0.3-0.5-0.1
Patch foraging water rate 6 sec1.11.62.4-0.8-1.51.4-1.31.51.4-1.3-1.0-1.2-1.3-1.2-1.3-1.2-1.2-1.1-0.7-1.5-1.30.9-1.2
Seeking ratio, delayed vs. immediate footshock1.21.32.0-1.4-1.11.0-0.71.31.4-1.1-1.1-1.2-1.2-1.3-1.1-1.1-1.1-0.8-1.3-1.4-1.30.8-1.4
Distance traveled before self-admin0.10.10.8-0.90.6-0.3-0.1-0.30.10.30.10.20.30.30.30.30.3-0.1-0.60.0-0.10.10.0
Distance traveled after self-admin4.14.55.7-2.4-2.02.2-2.32.22.3-2.1-2.2-2.2-2.1-2.0-2.0-2.1-2.1-2.2-2.3-1.9-2.02.0-2.0
Extensor digitorum longus weight0.20.61.00.80.7-0.80.8-1.0-1.00.80.60.90.80.70.90.90.90.81.00.60.2-0.40.7
Bone: elastic displacement0.00.00.00.0-0.1-0.00.2-0.1-0.1-0.0-0.10.00.00.1-0.00.20.20.1-0.0-0.0-0.10.20.2
Bone: elastic work1.82.43.0-1.5-1.51.5-1.51.51.5-1.5-1.6-1.5-1.5-1.7-1.5-1.5-1.5-1.5-1.6-1.7-1.51.6-1.5
Bone: endosteal estimation1.63.64.6-1.8-1.81.9-2.11.92.0-1.9-1.9-1.9-1.9-1.8-1.9-1.8-1.8-2.1-2.0-1.9-1.81.8-1.9
Bone: endosteal perimeter1.53.13.8-2.0-1.71.8-1.81.82.0-1.8-1.8-1.8-1.8-1.5-1.7-1.6-1.6-1.8-1.9-1.5-1.71.6-1.7
Epididymis fat weight0.10.20.70.4-0.40.4-0.30.40.4-0.4-0.3-0.3-0.4-0.5-0.3-0.3-0.3-0.20.0-0.8-0.70.4-0.8
Delta time in closed arm before/after self-admin2.72.63.4-1.0-1.61.6-1.61.61.5-1.6-1.6-1.6-1.6-1.8-1.7-1.7-1.7-1.6-1.3-1.8-1.81.7-1.5
Delta time in open arm before/after self-admin0.60.51.91.00.3-0.60.4-0.6-1.00.50.60.70.60.90.60.60.60.61.40.70.8-0.70.6
Diff in mean of infusions in LGA sessions0.50.61.3-0.71.1-0.70.2-0.6-0.20.90.70.60.81.00.90.90.90.4-0.20.80.9-0.90.8
Delay discount exponential model param0.60.61.81.30.7-0.70.7-0.8-0.90.70.70.80.71.00.80.90.90.80.70.70.2-0.40.2
Extinction: sum of active levers before priming3.43.44.3-1.2-1.71.9-1.71.81.8-1.8-1.8-1.9-1.8-2.1-1.9-1.9-1.9-1.9-2.0-1.9-1.92.0-1.9
Active lever presses in extinction session 62.72.64.1-1.5-1.41.6-1.81.41.5-1.6-1.8-1.7-1.6-1.6-1.4-1.5-1.5-1.8-2.0-1.4-1.42.0-1.5
Bone: final force1.72.83.8-1.4-1.71.7-1.71.71.6-1.7-1.6-1.7-1.7-1.9-1.7-1.8-1.8-1.7-1.6-1.5-1.51.6-1.6
Bone: final moment2.23.54.3-1.6-2.02.0-1.91.91.9-1.9-1.9-1.9-1.9-2.1-1.9-1.9-1.9-1.9-1.9-1.7-1.81.8-1.8
Food consumed during 24 hour testing period0.80.91.4-0.9-0.91.0-1.01.11.2-0.9-0.8-1.0-1.0-1.1-1.0-1.1-1.1-0.9-1.0-1.0-0.80.6-0.8
Glucose0.20.20.40.70.5-0.50.5-0.7-0.60.50.40.60.50.30.70.40.40.50.60.10.1-0.20.2
Heart weight0.10.20.5-0.7-0.30.3-0.10.50.7-0.3-0.3-0.3-0.4-0.5-0.4-0.4-0.4-0.2-0.5-0.4-0.50.2-0.4
Delay discount hyperbolic model param0.40.41.61.30.6-0.60.6-0.7-0.80.60.60.60.60.80.70.70.70.60.60.60.2-0.30.2
Intermittent access intake day 1-15 change2.52.53.4-1.3-1.71.6-1.51.61.5-1.5-1.5-1.6-1.6-1.6-1.6-1.6-1.6-1.4-1.2-1.7-1.81.5-1.8
Intermittent access intake escalation2.42.43.3-1.3-1.71.6-1.41.61.5-1.5-1.5-1.5-1.6-1.6-1.6-1.6-1.6-1.3-1.2-1.8-1.81.4-1.8
Intermittent access intake escalation 21.91.92.5-1.6-1.41.4-1.31.31.3-1.3-1.4-1.3-1.4-1.4-1.4-1.4-1.4-1.3-1.4-1.4-1.41.4-1.3
Intermitt. access day 1 inactive lever presses3.94.25.2-1.4-2.12.3-2.32.22.0-2.3-2.1-2.3-2.2-2.3-2.2-2.3-2.3-2.3-2.2-1.3-1.31.8-1.3
Intermitt. access day 15 inactive lever presses0.50.61.0-0.9-0.80.9-0.61.00.9-0.9-0.8-0.9-0.8-0.9-0.8-0.9-0.9-0.7-0.6-0.3-0.20.3-0.2
Intermitt. access escalation Index0.20.20.3-0.00.6-0.50.3-0.4-0.10.50.50.40.50.60.50.60.60.50.10.30.1-0.50.1
Intermittent access day 1 total infusions2.42.84.01.21.9-1.81.9-1.6-1.31.81.91.81.81.71.81.71.71.91.41.51.4-2.01.4
Intermittent access day 15 total infusions0.10.10.3-0.50.3-0.20.50.00.30.30.40.20.20.10.20.10.10.50.1-0.1-0.2-0.6-0.1
Intermittent access terminal intake (last 3 days)0.30.30.9-0.50.7-0.60.8-0.3-0.10.70.70.60.60.50.60.50.50.80.30.40.3-0.90.4
Intermittent access total infusions0.60.71.40.11.0-0.91.2-0.7-0.41.01.00.90.90.80.80.80.81.10.50.60.5-1.20.5
Intermittent access day 1 locomotion1.11.22.30.91.4-1.01.0-0.9-0.71.21.31.01.11.01.11.01.01.10.51.21.1-1.51.1
Intermittent access day 15 total locomotion0.00.10.30.20.3-0.10.20.10.30.30.40.10.10.10.10.10.10.3-0.00.1-0.2-0.6-0.1
Intermittent access total locomotion1.21.42.31.11.4-1.11.2-1.0-0.91.31.41.11.21.11.21.11.11.20.71.21.1-1.51.1
Intermittent access standard deviation5.65.97.4-2.7-2.32.4-2.32.52.6-2.3-2.3-2.4-2.4-2.5-2.5-2.5-2.5-2.3-2.7-2.5-2.42.1-2.4
Left kidney weight2.77.610.1-1.5-3.02.9-2.62.72.4-2.9-2.9-2.8-2.9-2.6-2.8-2.6-2.6-2.6-2.1-3.1-3.23.2-3.1
Right kidney weight5.014.017.3-2.8-3.93.8-3.53.63.4-3.9-4.0-3.8-3.9-3.6-3.8-3.5-3.5-3.6-3.4-4.2-4.04.1-4.0
Cocaine induced anxiety0.50.60.9-0.6-0.70.8-1.00.70.7-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.9-0.9-0.7-0.50.8-0.5
Post-drug Anxiety0.10.10.6-0.30.10.00.2-0.2-0.20.0-0.10.00.0-0.00.0-0.0-0.0-0.0-0.10.40.7-0.10.7
Baseline Anxiety1.21.32.21.01.0-1.01.3-1.0-1.11.01.01.01.01.00.91.01.01.21.31.41.4-1.31.5
Tail length5.215.919.4-4.4-4.24.0-4.23.93.8-4.0-4.2-4.0-4.0-4.0-3.9-3.9-3.9-4.0-3.8-3.9-3.84.1-3.9
Length with tail8.531.133.8-5.8-5.85.6-5.65.65.5-5.6-5.7-5.5-5.6-5.5-5.5-5.5-5.5-5.5-5.4-5.6-5.65.6-5.5
Length without tail5.512.014.4-2.9-3.73.5-3.53.63.5-3.5-3.4-3.4-3.5-3.4-3.6-3.5-3.5-3.3-3.0-3.6-3.83.4-3.6
Times rat made contact with spout0.60.71.71.30.8-0.91.0-1.0-1.00.90.91.00.90.11.00.10.11.01.10.10.2-0.40.1
Lifetime Intake0.80.91.70.51.1-1.01.3-0.9-0.61.11.11.01.00.91.00.90.91.20.70.70.5-1.10.6
Liver weight, left0.30.51.11.00.5-0.70.9-0.9-1.10.60.60.70.70.60.70.60.60.80.90.60.7-0.50.6
Liver weight, right0.10.10.60.1-0.0-0.10.3-0.3-0.60.10.10.20.20.30.30.40.40.30.50.50.8-0.10.5
Locomotor activity0.40.61.41.20.7-0.80.7-1.0-1.10.70.60.70.70.90.80.90.90.60.40.80.8-0.30.9
Locomotor testing distance0.40.61.51.20.8-0.80.7-0.9-1.00.80.70.80.81.00.90.90.90.70.50.60.6-0.40.5
Locomotor testing rearing2.03.14.71.71.6-1.91.8-1.8-1.91.81.82.01.81.81.81.81.81.92.21.61.2-1.51.1
Locomotion in novel chamber0.30.31.00.30.8-0.50.4-0.5-0.40.50.40.40.50.60.40.60.60.1-0.40.81.0-0.41.0
Locomotion in novel chamber post-restriction0.10.11.0-1.00.4-0.1-0.4-0.00.20.1-0.1-0.00.00.00.0-0.1-0.1-0.4-0.80.20.50.10.4
Fecal boli incidents, locomotor time 12.32.54.01.11.9-1.51.4-1.6-1.41.61.51.41.61.61.51.81.81.30.91.92.0-1.41.9
Change in fecal boli incidents, locomotor task0.20.20.5-0.2-0.60.6-0.70.30.1-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.7-0.3-0.1-0.00.60.0
Time >=10cm from walls, locomotor time 10.00.00.10.10.0-0.10.2-0.1-0.20.00.10.00.0-0.1-0.1-0.2-0.20.20.20.40.3-0.10.2
Bouts of movement, locomotor time 10.60.63.9-2.0-0.30.5-0.80.71.1-0.4-0.5-0.6-0.5-0.6-0.5-0.6-0.6-0.6-1.1-0.6-0.70.3-0.7
Total resting periods, locomotor time 10.50.53.8-2.0-0.20.4-0.60.61.0-0.3-0.5-0.5-0.4-0.6-0.5-0.5-0.5-0.6-1.2-0.5-0.50.3-0.5
Rest time, locomotor task time 11.21.32.30.21.5-1.20.8-1.2-0.91.31.11.21.31.11.21.31.30.70.31.01.5-1.11.5
Distance moved, locomotor task time 10.10.10.40.3-0.40.10.20.20.1-0.3-0.2-0.1-0.20.0-0.0-0.1-0.10.10.2-0.2-0.70.2-0.6
Vertical activity count, locomotor time 12.32.43.7-0.8-1.91.7-1.81.71.4-1.7-1.5-1.6-1.7-1.4-1.5-1.6-1.6-1.5-0.8-1.4-1.61.4-1.6
Time >=10cm from walls, locomotor time 21.92.02.80.41.5-1.41.3-1.4-1.31.51.41.41.51.51.41.41.41.30.91.71.7-1.51.6
Bouts of movement, locomotor time 20.10.10.7-0.80.2-0.20.3-0.10.10.30.10.20.2-0.30.2-0.1-0.10.1-0.0-0.1-0.2-0.1-0.1
Total resting periods, locomotor time 20.10.10.4-0.60.3-0.20.2-0.2-0.10.30.20.30.3-0.10.30.10.10.10.20.20.1-0.20.2
Rest time, locomotor task time 20.40.51.40.00.8-0.70.4-0.6-0.60.70.70.70.80.60.70.60.60.30.60.81.2-0.71.0
Distance moved, locomotor task time 20.10.10.30.50.0-0.30.4-0.3-0.30.30.30.30.30.40.30.30.30.50.6-0.2-0.3-0.4-0.1
Vertical activity count, locomotor time 20.80.91.4-0.7-1.10.9-1.01.01.0-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.9-0.9-0.8-1.1-1.20.8-1.0
Light reinforcement 10.10.10.40.40.2-0.30.2-0.2-0.30.30.40.30.20.30.20.30.30.30.40.40.2-0.50.6
Light reinforcement 22.63.54.82.21.9-1.91.7-1.8-1.91.81.91.81.81.81.81.81.81.71.71.92.0-1.92.2
Bone: marrow area1.73.74.8-1.8-1.91.9-2.22.02.0-1.9-1.9-1.9-1.9-1.8-2.0-1.8-1.8-2.1-2.1-1.9-1.81.9-1.9
Bone: maximum diameter1.52.73.3-1.5-1.81.8-1.61.71.6-1.7-1.8-1.8-1.7-1.6-1.7-1.6-1.6-1.6-1.6-1.5-1.61.6-1.6
Bone: maximum force2.74.76.0-1.9-2.22.2-2.22.22.2-2.2-2.1-2.1-2.2-2.4-2.2-2.3-2.3-2.1-2.1-2.1-2.12.1-2.1
Bone: maximum moment3.25.56.4-2.2-2.42.4-2.42.32.4-2.3-2.3-2.3-2.3-2.5-2.4-2.4-2.4-2.3-2.3-2.2-2.32.3-2.2
Mean time between licks in bursts0.00.00.1-0.3-0.30.2-0.20.30.1-0.2-0.2-0.3-0.20.3-0.30.10.1-0.2-0.10.20.4-0.1-0.0
Mean num. licks in bursts1.21.52.6-0.9-1.11.1-1.21.01.0-1.2-1.3-1.1-1.2-1.3-1.1-1.2-1.2-1.2-1.3-1.4-1.31.6-1.4
Cd content in liver0.10.10.40.3-0.10.1-0.00.00.1-0.1-0.1-0.0-0.1-0.4-0.1-0.2-0.20.0-0.0-0.6-0.60.3-0.6
Co content in liver0.30.41.61.30.4-0.40.3-0.5-0.70.40.50.40.50.70.40.60.60.40.70.70.7-0.60.8
Cu content in liver0.50.71.0-0.9-0.90.9-0.90.90.8-0.8-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.8-0.5-0.9-0.80.7-1.0
Fe content in liver0.00.00.00.20.2-0.10.1-0.1-0.10.10.10.10.10.10.10.10.10.10.10.20.2-0.20.1
K content in liver0.10.10.2-0.2-0.50.4-0.30.40.1-0.4-0.4-0.4-0.40.1-0.4-0.1-0.1-0.3-0.1-0.10.40.10.2
Mg content in liver0.40.51.50.50.3-0.40.5-0.5-0.80.40.50.40.50.90.40.80.80.50.70.81.2-0.71.1
Mn content in liver0.80.92.11.00.8-0.90.8-1.0-1.20.80.80.90.91.00.90.80.80.80.91.01.4-0.81.3
Na content in liver1.61.73.3-1.8-1.41.3-1.21.41.5-1.3-1.3-1.3-1.3-1.0-1.3-1.2-1.2-1.2-1.2-1.2-1.21.1-1.2
Rb content in liver0.10.10.4-0.20.1-0.10.10.0-0.00.10.20.10.10.40.20.30.30.20.20.30.6-0.50.3
Se content in liver7.79.410.83.23.0-3.03.1-3.1-3.33.03.03.13.03.03.03.03.03.03.03.23.3-2.93.2
Sr content in liver0.80.81.11.00.9-0.80.8-0.9-1.00.80.80.90.90.80.80.80.80.70.80.91.0-0.71.0
Zn content in liver0.10.10.30.60.0-0.10.0-0.1-0.30.10.20.10.10.30.10.30.30.10.40.40.5-0.30.4
Bone: minimum diameter3.26.08.9-3.0-2.52.5-2.62.62.7-2.4-2.4-2.5-2.5-2.2-2.4-2.3-2.3-2.5-2.6-2.1-2.22.1-2.1
Time in familiar zone, hab. session 10.30.30.8-0.5-0.40.4-0.50.30.3-0.4-0.6-0.4-0.4-0.7-0.4-0.7-0.7-0.5-0.5-0.5-0.90.9-0.7
Time in novel zone, hab. session 11.11.12.40.50.8-0.91.1-0.8-0.90.91.10.90.91.10.91.11.11.11.21.01.6-1.41.4
Total zone transitions, hab. session 10.00.00.2-0.20.4-0.2-0.1-0.10.10.30.20.20.20.10.40.20.20.0-0.10.1-0.0-0.30.2
Total locomotion distance, hab. session 11.11.63.8-1.9-1.11.2-1.41.31.4-1.2-1.3-1.3-1.2-1.2-1.1-1.1-1.1-1.4-1.6-1.2-0.71.0-1.0
Locomotion velocity, hab. session 10.70.91.8-1.3-0.81.0-1.21.01.0-0.9-1.0-1.0-0.9-0.9-0.8-0.8-0.8-1.1-1.4-0.9-0.50.9-0.8
Time in familiar zone, hab. session 22.42.43.4-1.7-1.61.7-1.81.51.4-1.7-1.7-1.7-1.6-1.3-1.6-1.5-1.5-1.8-1.8-1.2-0.91.6-1.1
Time in novel zone, hab. session 21.51.52.21.31.3-1.41.5-1.3-1.21.31.31.31.31.01.31.11.11.41.40.90.8-1.21.0
Total zone transitions, hab. session 23.24.14.81.52.1-2.11.8-2.0-1.92.12.12.12.12.02.12.12.11.91.92.02.1-2.22.1
Total locomotion distance, hab. session 20.10.10.6-0.20.4-0.30.1-0.2-0.20.40.40.30.40.20.40.40.40.20.10.20.8-0.60.4
Locomotion velocity, hab. session 20.20.20.80.10.5-0.40.2-0.3-0.30.50.50.40.50.30.60.50.50.30.30.40.9-0.70.5
Novel to familiar place preference ratio0.20.20.4-0.6-0.60.4-0.20.50.4-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.4-0.3-0.1-0.4-0.40.20.1
Novelty place preference0.10.10.3-0.5-0.40.3-0.10.40.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.20.0-0.3-0.30.10.1
Time in novel zone, NPP test0.00.00.1-0.3-0.20.10.10.10.1-0.1-0.1-0.1-0.1-0.0-0.1-0.0-0.00.10.2-0.1-0.2-0.10.3
Total zone transitions, NPP test0.10.10.30.60.5-0.40.1-0.4-0.30.50.40.40.40.30.50.40.40.20.10.30.1-0.30.4
Total locomotion distance, NPP test2.43.34.0-1.9-1.71.8-2.01.81.8-1.8-1.8-1.8-1.8-1.9-1.7-1.8-1.8-1.9-2.0-1.8-1.61.8-1.7
Locomotion velocity, NPP test2.63.64.6-2.0-1.81.9-2.11.81.9-1.9-1.9-1.9-1.9-2.0-1.8-1.9-1.9-2.0-2.1-2.0-1.61.9-1.7
Intraocular pressure0.00.00.2-0.10.4-0.20.2-0.10.10.20.20.20.20.30.10.20.20.1-0.20.50.0-0.30.2
Delta distance traveled before/after self-admin5.35.77.4-1.9-2.72.6-2.42.62.3-2.6-2.4-2.5-2.6-2.4-2.5-2.4-2.4-2.3-2.0-2.1-2.22.2-2.2
Delta ambulatory time before/after self-admin5.86.48.4-1.7-2.92.7-2.62.82.5-2.7-2.5-2.6-2.7-2.7-2.7-2.7-2.7-2.5-1.9-2.4-2.42.3-2.5
Parametrial fat weight0.10.22.21.5-0.2-0.10.3-0.5-0.9-0.1-0.10.10.1-0.00.0-0.1-0.10.10.60.30.40.50.2
Pavlov. Cond. lever latency0.20.20.7-0.4-0.30.3-0.20.30.4-0.3-0.4-0.3-0.3-0.4-0.3-0.4-0.4-0.3-0.4-0.7-0.80.6-0.8
Pavlov. Cond. magazine entry latency0.30.40.80.40.6-0.70.6-0.7-0.80.60.70.70.70.50.70.60.60.60.70.60.9-0.60.7
Pavlov. Cond. change in total contacts0.30.31.10.30.5-0.40.2-0.3-0.40.50.50.40.40.50.50.50.50.30.50.70.8-0.81.0
Pavlov. Cond. index score0.40.61.30.70.6-0.70.5-0.7-0.80.70.70.70.70.60.70.70.70.60.80.91.1-0.81.1
Pavlov. Cond. latency score0.20.30.90.40.5-0.40.3-0.4-0.60.40.50.40.50.50.50.50.50.30.50.70.9-0.60.9
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.30.3-0.40.30.2-0.3-0.2-0.3-0.30.0-0.3-0.1-0.1-0.4-0.30.40.4-0.00.5
Pavlov. Cond. magazine entry number0.50.61.0-0.5-0.70.8-0.70.80.9-0.8-0.8-0.8-0.8-0.6-0.8-0.7-0.7-0.8-0.9-0.7-1.00.8-0.8
Pavlov. Cond. intertrial magazine entries0.91.11.60.91.2-1.11.0-1.1-0.91.11.01.11.11.21.11.21.21.00.91.30.7-1.01.1
Pavlov. Cond. lever-magazine prob. diff.0.60.71.60.70.7-0.80.6-0.8-0.90.80.80.80.80.70.80.80.80.70.90.91.3-0.91.2
Pavlov. Cond. response bias0.10.10.50.10.2-0.30.2-0.4-0.50.30.30.30.30.30.30.30.30.20.40.50.7-0.30.7
Pavlov. Cond. lever latency5.27.07.72.62.6-2.72.7-2.7-2.72.72.72.72.72.72.62.82.82.72.72.62.5-2.52.3
Pavlov. Cond. magazine entry latency3.13.64.2-2.0-1.91.9-1.92.01.9-1.9-1.9-2.0-1.9-1.9-2.0-2.0-2.0-2.0-2.1-1.7-1.41.7-1.5
Pavlov. Cond. change in total contacts8.511.713.4-3.7-3.43.5-3.33.63.7-3.4-3.4-3.5-3.4-3.4-3.4-3.4-3.4-3.3-3.4-3.4-3.43.1-3.1
Pavlov. Cond. index score5.46.98.1-2.6-2.62.7-2.62.72.7-2.6-2.6-2.6-2.6-2.8-2.6-2.8-2.8-2.6-2.7-2.7-2.42.5-2.4
Pavlov. Cond. latency score5.16.47.3-2.5-2.52.5-2.52.62.6-2.5-2.5-2.6-2.5-2.7-2.5-2.7-2.7-2.5-2.6-2.5-2.32.3-2.2
Pavlov. Cond. lever contacts4.76.58.1-2.6-2.52.6-2.52.62.6-2.5-2.5-2.5-2.5-2.8-2.4-2.9-2.9-2.4-2.4-2.6-2.52.3-2.4
Pavlov. Cond. magazine entry number4.04.86.12.02.1-2.12.1-2.2-2.22.12.22.12.22.52.12.42.42.12.12.42.3-2.12.2
Pavlov. Cond. intertrial magazine entries1.01.33.31.81.0-1.00.9-1.1-1.21.01.11.01.01.21.11.41.41.01.31.21.0-1.01.1
Pavlov. Cond. lever-magazine prob. diff.5.46.87.9-2.6-2.62.6-2.52.62.6-2.6-2.6-2.6-2.6-2.8-2.6-2.8-2.8-2.5-2.6-2.7-2.42.5-2.4
Pavlov. Cond. response bias5.37.28.7-2.7-2.62.7-2.62.72.8-2.6-2.6-2.6-2.6-2.9-2.6-3.0-3.0-2.5-2.5-2.8-2.72.4-2.6
Time in closed arm before self-admin2.63.04.00.81.7-1.82.0-1.7-1.51.81.71.71.71.81.81.71.72.01.81.81.7-1.91.6
Time in closed arm after self-admin0.10.10.7-0.80.3-0.00.10.00.40.0-0.1-0.1-0.0-0.2-0.0-0.1-0.1-0.1-0.6-0.00.1-0.00.3
Time in open arm before self-admin5.15.57.1-1.4-2.42.5-2.52.22.1-2.4-2.4-2.4-2.4-2.7-2.5-2.6-2.6-2.5-2.5-2.1-2.12.5-2.0
Time in open arm after self-admin1.61.73.0-0.1-1.71.5-1.51.40.9-1.5-1.3-1.3-1.4-1.2-1.5-1.4-1.4-1.4-0.5-1.3-1.21.3-1.3
Bone: periosteal estimation2.14.44.7-2.0-2.12.1-2.22.12.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.2-2.1-1.9-2.12.1-2.0
Bone: periosteal perimeter1.42.33.7-1.9-1.51.5-1.41.51.6-1.5-1.6-1.6-1.5-1.3-1.5-1.5-1.5-1.5-1.8-1.2-1.41.6-1.3
Bone: post-yield work1.82.43.2-1.5-1.51.6-1.71.71.8-1.6-1.5-1.6-1.6-1.5-1.6-1.6-1.6-1.6-1.6-1.5-1.51.2-1.5
Progressive ratio test 1 active lever presses0.30.30.8-0.6-0.20.5-0.50.60.9-0.4-0.2-0.5-0.5-0.5-0.4-0.5-0.5-0.4-0.7-0.6-0.80.2-0.7
Progressive ratio test 1 breakpoint0.60.61.2-0.8-0.50.8-0.80.91.1-0.6-0.6-0.7-0.7-0.8-0.7-0.8-0.8-0.7-1.1-0.8-1.00.5-0.9
Progressive ratio test 1 inactive lever presses0.40.41.0-1.0-0.50.7-0.70.91.0-0.5-0.5-0.6-0.6-0.7-0.6-0.7-0.7-0.6-0.7-0.2-0.40.1-0.3
Progressive ratio test 2 active lever presses0.10.10.4-0.60.4-0.10.5-0.00.30.20.20.10.10.10.20.10.10.4-0.2-0.1-0.3-0.3-0.3
Progressive ratio test 2 breakpoint0.10.10.3-0.40.5-0.20.6-0.10.20.30.30.20.20.20.20.20.20.5-0.20.1-0.2-0.3-0.2
Progressive ratio test 2 inactive lever presses0.60.74.4-2.1-0.20.6-0.50.91.4-0.5-0.5-0.8-0.6-0.6-0.5-0.6-0.6-0.6-1.7-0.1-0.4-0.0-0.3
Incentive Sensitization - Responses0.20.20.5-0.20.6-0.40.7-0.4-0.10.50.40.40.40.40.50.40.40.60.10.4-0.0-0.4-0.0
Incentive Sensitization - Breakpoint0.20.20.5-0.10.6-0.40.7-0.4-0.10.50.40.40.40.40.40.40.40.70.20.3-0.1-0.4-0.1
Sum of active levers in priming session hrs 5-60.10.10.5-0.2-0.10.3-0.40.30.4-0.2-0.2-0.3-0.2-0.2-0.1-0.2-0.2-0.4-0.7-0.2-0.30.3-0.4
Progressive ratio0.00.00.20.20.10.2-0.40.10.1-0.1-0.1-0.2-0.1-0.0-0.2-0.0-0.0-0.3-0.30.10.20.00.1
Food seeking constrained by brief footshock3.34.04.7-2.0-1.92.1-2.12.12.1-2.1-2.1-2.1-2.1-2.0-2.1-2.0-2.0-2.2-2.1-1.8-1.72.0-1.7
Seeking ratio, punishment vs. effort0.60.71.6-1.3-0.90.8-0.60.90.9-0.8-0.8-0.8-0.9-0.9-0.8-0.9-0.9-0.7-0.8-0.8-0.80.7-0.7
Retroperitoneal fat weight1.44.67.62.82.0-2.22.5-2.4-2.52.12.02.22.21.92.11.91.92.22.51.91.7-1.61.9
Reaction time number correct0.00.10.50.70.0-0.1-0.1-0.1-0.20.20.20.20.2-0.10.2-0.0-0.00.10.6-0.1-0.1-0.1-0.0
Reaction time mean minus median0.60.81.4-0.2-1.21.0-0.60.90.7-1.1-1.0-1.0-1.1-0.9-1.0-0.9-0.9-0.7-0.4-0.9-0.80.9-0.9
Reaction time mean minus median AUC1.21.62.9-0.3-1.71.4-1.01.30.9-1.5-1.3-1.4-1.5-1.4-1.4-1.4-1.4-1.0-0.5-1.3-1.31.3-1.3
Reaction time num false alarms0.91.22.01.30.9-1.11.4-1.0-1.11.01.11.11.01.10.91.21.21.31.31.00.9-1.10.8
Reaction time num false alarms AUC1.11.52.61.61.1-1.21.5-1.2-1.31.11.31.21.11.21.11.21.21.41.31.11.1-1.21.1
Reaction time trials correct on left0.00.10.50.70.0-0.1-0.1-0.1-0.20.20.20.20.2-0.10.2-0.0-0.00.10.6-0.1-0.1-0.1-0.0
Reaction time trials on left0.00.10.60.8-0.0-0.1-0.0-0.1-0.30.10.20.20.2-0.10.10.00.00.10.6-0.1-0.1-0.0-0.1
Reaction time mean0.20.30.90.5-0.60.4-0.00.50.3-0.5-0.4-0.5-0.6-0.6-0.6-0.7-0.7-0.10.1-0.7-0.80.5-0.9
Reaction time mean AUC0.20.20.60.8-0.50.40.00.40.2-0.5-0.4-0.4-0.5-0.5-0.5-0.6-0.6-0.00.2-0.6-0.60.4-0.7
Median of all reaction times0.10.10.50.7-0.20.10.20.20.1-0.2-0.1-0.2-0.2-0.3-0.2-0.3-0.30.20.2-0.4-0.60.2-0.7
Reaction time omissions0.00.10.40.6-0.40.10.10.1-0.3-0.2-0.1-0.1-0.20.2-0.20.20.20.10.4-0.10.00.1-0.2
Reaction time false alarm rate0.70.91.60.90.9-1.01.3-0.9-0.90.90.90.90.91.00.81.01.01.10.80.90.9-1.00.9
Reaction time premature initiation rate0.10.10.5-0.4-0.10.3-0.70.40.4-0.2-0.2-0.3-0.2-0.0-0.2-0.2-0.2-0.4-0.5-0.40.2-0.1-0.1
Reaction time premature initiations0.00.10.40.0-0.10.3-0.60.40.3-0.1-0.0-0.1-0.10.0-0.1-0.1-0.1-0.4-0.1-0.30.1-0.2-0.1
Std. dev. reaction times0.81.11.8-0.0-1.31.1-0.61.10.9-1.2-1.0-1.1-1.2-1.1-1.2-1.1-1.1-0.7-0.4-1.2-1.31.0-1.3
Reaction time trials completed0.00.10.60.8-0.0-0.1-0.0-0.1-0.30.10.20.20.2-0.10.10.00.00.10.6-0.1-0.1-0.0-0.1
Reaction time trials AUC0.10.10.91.00.1-0.10.1-0.2-0.40.20.30.30.30.00.20.10.10.20.70.0-0.1-0.10.0
Run reversals in cocaine runway, females0.50.51.50.1-0.90.6-0.50.80.7-0.7-0.5-0.7-0.8-0.7-0.8-0.7-0.7-0.4-0.2-1.0-1.20.6-1.1
Run reversals in cocaine runway, males0.20.21.71.3-0.40.10.2-0.2-0.7-0.2-0.2-0.1-0.1-0.2-0.1-0.2-0.2-0.10.60.20.50.40.4
Latency to leave start box in cocaine runway0.10.10.70.2-0.20.3-0.30.40.4-0.2-0.0-0.2-0.2-0.0-0.1-0.1-0.1-0.1-0.1-0.6-0.70.1-0.8
Latency to leave start box in cocaine runway, F0.00.00.20.4-0.20.1-0.10.20.0-0.00.20.0-0.0-0.00.0-0.1-0.10.10.5-0.2-0.2-0.3-0.2
Latency to leave start box in cocaine runway, M0.10.10.4-0.2-0.00.0-0.10.10.2-0.0-0.1-0.0-0.00.20.10.20.20.0-0.2-0.4-0.50.1-0.7
Std. dev. time between licks in bursts0.40.52.0-1.4-0.70.8-0.91.00.9-0.7-0.7-0.8-0.70.0-0.8-0.1-0.1-0.9-0.90.20.30.0-0.0
Total sessions with >9 infusions1.21.32.31.51.1-1.01.2-1.2-1.21.11.21.21.11.11.11.11.11.21.51.10.9-1.10.9
Short access day 1 total inactive lever presses0.10.21.4-1.2-0.00.2-0.40.60.8-0.1-0.1-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.50.1-0.0-0.3-0.0
Short access day 10 total inactive lever presses1.31.52.7-1.5-1.01.3-1.21.41.5-1.2-1.3-1.3-1.2-1.1-1.2-1.1-1.1-1.3-1.6-0.8-0.81.0-0.9
Short access day 1 total infusions0.10.10.30.10.4-0.40.4-0.4-0.30.40.40.40.40.40.40.40.40.50.40.50.1-0.40.2
Short access day 10 total infusions0.50.61.21.10.9-0.81.0-0.8-0.70.80.90.80.70.70.70.70.70.90.60.60.4-0.80.5
Short access total infusions1.11.31.91.31.2-1.11.4-1.2-1.11.21.21.21.11.11.11.11.11.31.01.00.7-1.00.7
Short access day 1 locomotion0.40.43.31.80.3-0.30.4-0.4-0.70.40.60.40.40.30.30.30.30.50.90.60.4-0.60.5
Short access day 10 total locomotion0.70.71.8-0.3-0.61.0-1.01.01.0-0.8-0.6-1.0-0.9-0.9-0.9-0.9-0.9-1.0-1.4-0.6-0.50.5-0.5
Short access total locomotion0.80.91.81.41.0-0.80.8-0.9-0.90.91.00.80.90.80.80.80.80.80.51.11.1-1.11.1
One hour access (0.3 mA shock)0.91.02.0-1.4-0.81.0-0.71.11.4-0.9-0.8-1.0-0.9-1.0-1.0-1.0-1.0-0.7-1.3-1.1-1.10.6-1.1
Compulsive drug intake0.10.10.8-0.9-0.40.2-0.20.30.2-0.2-0.4-0.1-0.2-0.1-0.2-0.1-0.1-0.20.0-0.3-0.10.2-0.1
One hour access (shock baseline)0.00.10.4-0.30.20.00.20.20.40.10.1-0.1-0.0-0.1-0.0-0.1-0.10.2-0.6-0.2-0.2-0.3-0.2
Social response proportion2.32.44.3-2.0-1.51.6-1.61.61.7-1.6-1.6-1.7-1.6-1.5-1.6-1.5-1.5-1.7-2.1-1.1-0.91.4-0.9
Social responses0.81.02.1-0.8-1.11.2-1.31.11.0-1.2-1.1-1.2-1.1-0.7-1.2-0.8-0.8-1.3-1.5-0.2-0.10.80.2
Social time2.83.64.6-1.6-1.81.9-2.02.12.1-1.9-1.8-1.9-1.9-1.9-2.0-2.0-2.0-1.9-2.1-1.9-1.91.7-1.7
Soleus weight0.10.30.80.90.4-0.40.2-0.6-0.70.50.60.50.50.50.50.60.60.30.60.60.4-0.40.7
Bone: stiffness1.42.22.8-1.4-1.41.5-1.51.51.5-1.4-1.4-1.4-1.4-1.7-1.4-1.6-1.6-1.4-1.5-1.5-1.31.4-1.4
Tibialis anterior weight0.00.10.30.30.3-0.40.2-0.6-0.60.40.20.50.40.30.40.30.30.20.60.2-0.30.20.1
Time to tail flick, vehicle, before self-admin1.11.22.00.91.2-1.11.4-1.1-1.01.11.11.11.11.11.01.11.11.20.90.91.0-1.10.9
Time to tail flick, vehicle, after self-admin0.10.10.8-0.90.10.0-0.10.10.1-0.1-0.2-0.1-0.10.0-0.00.00.0-0.2-0.60.30.50.00.5
Time to tail flick, test, before self-admin0.30.31.10.50.3-0.60.9-0.3-0.30.60.70.60.50.30.50.40.41.01.1-0.00.0-0.9-0.1
Time to tail flick, test, after self-admin0.00.00.20.3-0.20.1-0.10.1-0.10.00.1-0.0-0.0-0.1-0.0-0.0-0.00.10.4-0.1-0.0-0.10.1
Delta time to tail flick, vehicle, before/after SA0.90.91.4-0.9-1.11.0-1.21.00.9-1.0-1.0-1.0-1.0-0.9-0.9-0.9-0.9-1.1-0.8-0.6-0.60.8-0.4
Delta time to tail flick, test, before/after SA0.10.10.60.40.2-0.1-0.2-0.4-0.50.20.10.20.30.30.20.30.3-0.10.20.70.60.10.8
Tibia length2.87.911.4-2.1-2.72.7-2.62.72.7-2.7-2.7-2.6-2.7-3.2-2.7-3.1-3.1-2.6-2.5-3.4-3.22.8-3.1
Ambulatory time before self-admin0.10.10.4-0.60.6-0.3-0.1-0.30.00.30.10.20.30.40.40.30.3-0.1-0.40.30.2-0.10.2
Ambulatory time after self-admin7.58.39.7-2.7-2.82.9-3.13.03.1-2.9-2.8-2.9-2.9-2.9-2.8-2.9-2.9-3.0-2.9-2.7-2.72.7-2.7
Bone: tissue strength3.83.74.6-2.0-2.12.0-1.92.12.0-1.9-1.8-2.0-2.0-2.0-2.0-2.1-2.1-1.8-1.7-1.8-1.71.6-1.8
Total heroin consumption0.30.31.4-1.0-0.10.5-0.70.50.9-0.4-0.4-0.6-0.4-0.3-0.3-0.4-0.4-0.6-1.2-0.7-0.40.3-0.6
Bone: trabecular number1.52.33.4-0.5-1.51.6-1.61.51.4-1.5-1.4-1.5-1.5-1.8-1.5-1.6-1.6-1.5-1.4-1.8-1.61.5-1.6
Bone: trabecular spacing0.30.41.8-1.3-0.70.6-0.60.50.4-0.6-0.7-0.6-0.6-0.3-0.6-0.4-0.4-0.6-0.6-0.4-0.10.6-0.3
Bone: trabecular thickness0.10.10.80.90.2-0.30.4-0.3-0.30.30.30.30.30.00.30.20.20.50.6-0.1-0.3-0.1-0.1
Bone: trabecular tissue density2.43.44.91.91.9-2.02.1-2.2-2.21.91.72.01.91.72.01.71.71.91.81.71.4-1.21.6
Water consumed over 24 hours0.40.51.1-0.2-0.70.7-0.70.70.7-0.7-0.6-0.6-0.7-1.0-0.7-0.9-0.9-0.6-0.6-0.9-0.80.7-0.8
Number of responses in last shaping day0.20.21.1-1.10.5-0.30.0-0.20.20.40.30.20.30.50.40.50.50.2-0.70.40.2-0.60.2