Capn12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Capn12 0.04 0.03 9.6e-06 0.05 0.03 0.04 0.05 1.6e-06 7.3e-05 2.1e-05 4.4e-06
2 pVTA gene expression Capn12 0.1 0.06 1.5e-04 0.12 0.08 0.1 0.1 5.2e-06 1.9e-04 5.7e-05 3.9e-05
3 Brain gene expression Capn12 0.03 0.02 2.6e-03 0 0.01 0 0.01 1.7e-01 6.3e-02 9.8e-02 6.0e-02
4 OFC alternative polyA NM_001110808.1 0.14 0.11 5.0e-03 0.06 0.04 0.02 0.05 1.2e-02 4.3e-02 1.0e-01 2.3e-02
5 Adipose gene expression Capn12 0.03 0.03 3.5e-03 0.01 0 0 0 3.0e-02 1.2e-01 1.6e-01 1.5e-01
6 IL mRNA stability Capn12 0.13 0.09 3.6e-03 0.04 0.08 0.09 0.07 5.0e-02 4.7e-03 3.7e-03 8.5e-03
7 PL gene expression Capn12 0.05 0.03 2.0e-04 0.02 0.02 0.03 0.02 2.2e-03 1.2e-03 3.4e-04 2.3e-03
8 BLA gene expression Capn12 0.04 0.04 5.1e-03 0.04 0.03 0.04 0.03 3.4e-03 6.4e-03 5.6e-03 9.6e-03
9 Brain alternative polyA XM_039111580.1 0.05 0.04 2.7e-04 0.03 0.03 0.03 0.03 1.3e-03 3.9e-04 1.8e-03 8.6e-04
10 Brain alternative polyA NM_001110808.1 0.06 0.04 2.2e-04 0.03 0.04 0.03 0.03 1.1e-03 3.0e-04 1.4e-03 1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.30.51.10.20.20.4-0.20.20.80.90.71.1-1.0
Area under the delay curve0.10.10.3-0.5-0.40.10.50.2-0.1-0.40.0-0.30.3
BMI with tail0.10.30.80.70.7-0.7-0.60.4-0.90.20.5-0.10.2
BMI without tail0.20.50.8-0.7-0.70.50.7-0.80.3-0.8-0.6-0.90.9
Body weight2.39.714.6-3.6-3.63.83.6-2.93.6-2.9-2.9-1.61.6
Weight adjusted by age0.10.10.20.40.3-0.4-0.40.2-0.40.30.30.0-0.0
Bone surface0.40.82.6-0.8-0.81.30.8-0.81.60.1-0.30.6-0.6
Bone volume0.40.82.7-0.7-0.71.30.7-0.81.60.1-0.30.6-0.6
Breakpoint value in progressive ratio session2.12.36.1-1.2-1.20.31.0-1.1-0.5-1.9-1.2-2.52.4
Number of licking bursts2.42.84.61.71.7-1.2-1.71.3-0.72.01.42.1-2.1
Context. condit. distance diff. score0.10.10.10.30.3-0.3-0.30.3-0.20.30.20.1-0.0
Locomotion velocity, session 12.32.54.31.71.7-2.1-1.71.7-2.11.21.70.7-0.7
Locomotion distance, session 10.70.91.2-1.1-1.11.01.0-0.81.0-1.0-1.0-0.60.6
Locomotion velocity, session 20.30.30.50.60.6-0.6-0.60.7-0.50.40.70.4-0.3
Locomotion distance, session 20.50.71.60.90.8-1.1-0.80.9-1.30.30.8-0.40.4
Locomotion velocity, session 30.80.93.30.60.60.1-0.60.40.51.00.31.8-1.8
Locomotion distance, session 35.15.57.2-2.5-2.62.72.6-2.62.5-2.3-2.6-1.31.3
Stereotopy head waving bouts, day 30.70.81.71.21.1-1.2-1.00.5-1.30.50.6-0.20.3
Stereotopy head waving duration, day 32.53.04.22.02.0-2.1-1.91.7-2.11.51.70.8-0.8
Locomotion velocity, session 70.20.20.8-0.0-0.00.50.10.10.70.30.10.9-0.9
Locomotion distance, session 70.20.31.2-0.3-0.30.80.3-0.41.10.1-0.20.5-0.5
Stereotopy head waving bouts, day 70.10.10.20.40.3-0.3-0.20.1-0.40.10.2-0.40.4
Stereotopy head waving duration, day 70.91.12.51.21.2-1.4-1.10.9-1.60.71.0-0.10.1
Locomotion velocity, session 83.03.64.82.22.2-1.9-2.11.8-1.51.91.91.7-1.7
Locomotion distance, session 80.40.51.30.80.8-1.0-0.70.7-1.10.30.7-0.40.5
Degree of sensitization distance3.03.14.11.81.8-1.6-1.91.9-1.22.02.01.5-1.5
Degree of sensitization stereotypy0.20.20.60.10.1-0.3-0.0-0.1-0.6-0.3-0.0-0.80.8
Conditioned locomotion0.40.51.6-0.4-0.41.00.6-0.91.3-0.0-0.80.4-0.3
Cocaine response after cond. corrected0.40.51.3-0.6-0.61.00.7-0.81.1-0.4-0.80.1-0.0
Cocaine response after cond. not corrected0.70.81.8-0.7-0.71.20.9-1.21.3-0.6-1.0-0.10.2
Cocaine response before conditioning1.51.93.1-1.1-1.21.31.3-1.81.0-1.4-1.5-1.51.5
Saline control response0.81.13.3-0.7-0.70.20.8-0.9-0.3-1.1-0.8-1.81.8
Bone: connectivity density0.60.91.90.80.7-0.3-0.80.90.21.31.21.4-1.4
Bone: cortical apparent density1.92.53.81.81.8-2.0-1.81.7-1.91.31.70.2-0.2
Bone: cortical area1.92.83.5-1.7-1.71.61.8-1.91.3-1.7-1.6-1.71.7
Bone: cortical porosity0.60.71.21.11.0-0.9-0.90.7-1.10.50.70.4-0.4
Bone: cortical porosity0.70.81.41.11.1-1.0-0.90.8-1.20.60.70.4-0.4
Bone: cortical thickness0.81.31.8-1.1-1.11.11.1-1.30.9-1.1-1.1-1.21.2
Bone: cortical thickness0.10.10.20.50.50.1-0.30.20.40.50.20.4-0.4
Bone: cortical tissue density2.22.94.32.01.9-2.1-1.91.9-2.01.51.90.4-0.4
Condit. Reinf. active minus inactive responses0.30.40.70.70.7-0.4-0.70.4-0.10.80.50.7-0.7
Condit. Reinf. active-inactive response ratio0.20.30.40.60.6-0.6-0.60.2-0.50.60.40.3-0.3
Condit. Reinf. active responses1.01.21.91.21.2-0.7-1.21.1-0.21.41.21.2-1.2
Condit. Reinf. inactive responses0.50.61.00.80.8-0.4-0.71.0-0.00.91.00.8-0.8
Incentive salience index mean0.20.30.80.20.20.3-0.20.00.70.50.10.9-0.9
Condit. Reinf. lever presses0.20.31.1-0.5-0.50.80.5-0.31.1-0.2-0.40.4-0.4
Condit. Reinf. active minus inactive responses3.84.76.4-2.2-2.22.02.2-2.51.6-2.3-2.5-2.12.1
Condit. Reinf. active-inactive response ratio3.03.15.6-1.4-1.51.21.6-1.90.7-1.9-2.0-2.42.4
Condit. Reinf. active responses4.35.97.9-2.5-2.52.32.5-2.81.9-2.6-2.7-2.22.1
Condit. Reinf. inactive responses1.31.62.3-1.5-1.51.21.4-1.40.9-1.5-1.3-1.01.0
Condit. Reinf. lever presses5.98.010.0-3.2-3.13.13.0-3.23.0-2.8-3.1-1.71.6
Condit. Reinf. lever reinforcers received5.07.09.5-2.7-2.72.72.8-3.12.4-2.7-3.0-2.02.0
Conditioned reinforcement - actives0.50.51.2-0.6-0.80.90.7-1.11.1-0.3-0.60.2-0.2
Conditioned reinforcement - inactives1.61.84.0-1.4-1.51.81.4-1.32.0-1.0-1.5-0.20.2
Conditioned locomotion0.91.11.91.21.1-0.8-1.10.5-0.41.20.81.4-1.3
Patch foraging indifference point 0 sec0.30.40.9-0.6-0.60.80.6-0.80.9-0.6-0.7-0.30.3
Patch foraging indifference point AUC0.70.82.60.60.6-1.2-0.51.1-1.60.11.1-0.60.6
Delay disc. indifference point, 0s delay1.11.22.4-1.1-1.10.41.3-0.6-0.1-1.4-0.6-1.51.5
Delay disc. indifference point, 16s delay1.51.52.8-1.5-1.51.41.7-1.01.4-1.2-1.0-0.40.3
Delay disc. indifference point, 2s delay0.00.00.1-0.3-0.2-0.20.00.3-0.2-0.00.20.0-0.1
Delay disc. indifference point, 24s delay1.21.12.4-1.4-1.41.41.3-0.51.5-0.8-0.8-0.10.1
Delay disc. indifference point, 4s delay0.10.10.2-0.4-0.40.30.5-0.20.2-0.4-0.1-0.30.3
Delay disc. indifference point, 8s delay0.80.82.00.70.8-1.3-0.81.2-1.40.51.1-0.00.0
Indifference point function ln k0.70.93.3-0.7-0.71.40.7-1.01.8-0.1-0.90.7-0.7
Indifference point function log k0.70.93.3-0.7-0.71.40.7-1.01.8-0.1-0.90.7-0.7
Patch foraging total patch changes 0 sec0.40.61.2-0.7-0.71.00.7-0.91.1-0.6-0.8-0.30.3
Patch foraging total patch changes 12 sec0.40.51.0-0.7-0.70.40.7-0.40.1-1.0-0.4-1.01.0
Patch foraging total patch changes 18 sec0.70.92.40.30.3-1.0-0.30.7-1.6-0.50.5-1.41.4
Patch foraging total patch changes 24 sec0.60.71.2-1.0-1.00.71.0-0.60.5-1.1-0.6-0.80.8
Patch foraging total patch changes 6 sec0.20.31.0-0.3-0.40.10.4-0.2-0.2-0.7-0.2-1.01.0
Patch foraging time to switch 0 sec0.91.42.61.21.2-1.2-1.31.6-1.11.21.30.8-0.8
Patch foraging water rate 0 sec0.81.23.40.90.9-0.2-0.90.70.21.40.71.8-1.8
Patch foraging water rate 12 sec0.81.23.9-1.0-1.01.61.0-0.92.0-0.3-1.20.5-0.5
Patch foraging water rate 18 sec1.11.54.01.01.1-0.5-1.10.70.11.50.82.0-2.0
Patch foraging water rate 24 sec0.40.51.6-0.4-0.41.00.4-0.91.30.0-0.90.4-0.4
Patch foraging water rate 6 sec0.40.51.5-0.2-0.20.80.2-0.31.10.5-0.31.2-1.2
Seeking ratio, delayed vs. immediate footshock0.91.11.5-1.0-0.91.01.0-1.10.8-1.1-1.2-1.11.1
Distance traveled before self-admin1.51.62.3-1.2-1.21.21.2-1.51.0-1.3-1.5-1.11.1
Distance traveled after self-admin4.75.26.6-2.6-2.62.42.5-2.52.2-2.2-2.4-1.61.6
Extensor digitorum longus weight0.20.60.80.90.9-0.8-0.90.7-0.70.80.90.8-0.8
Bone: elastic displacement0.10.10.10.20.2-0.1-0.20.2-0.00.30.40.4-0.4
Bone: elastic work1.82.33.5-1.6-1.61.91.6-1.71.8-1.4-1.5-0.80.7
Bone: endosteal estimation1.12.53.7-1.8-1.81.31.7-1.50.8-1.9-1.4-1.71.6
Bone: endosteal perimeter1.02.03.0-1.7-1.71.31.6-1.41.0-1.6-1.3-1.11.1
Epididymis fat weight0.00.00.0-0.0-0.0-0.10.00.2-0.2-0.10.2-0.10.1
Delta time in closed arm before/after self-admin1.01.02.6-1.1-1.11.41.2-0.71.6-0.5-0.60.5-0.5
Delta time in open arm before/after self-admin0.20.10.40.60.6-0.3-0.50.1-0.50.40.0-0.00.1
Diff in mean of infusions in LGA sessions0.40.51.6-0.2-0.1-0.40.1-0.1-0.8-0.7-0.3-1.31.3
Delay discount exponential model param0.10.10.20.50.4-0.1-0.5-0.1-0.00.30.00.3-0.2
Extinction: sum of active levers before priming1.71.73.6-1.2-1.20.61.2-1.0-0.0-1.7-1.1-1.91.9
Active lever presses in extinction session 60.40.40.8-0.9-0.90.40.7-0.30.2-0.8-0.3-0.80.8
Bone: final force1.52.42.8-1.7-1.71.71.7-1.61.5-1.5-1.5-1.21.2
Bone: final moment2.23.54.3-2.0-2.02.12.0-2.11.9-1.8-1.9-1.41.4
Food consumed during 24 hour testing period0.40.41.0-0.7-0.60.80.6-0.71.0-0.3-0.70.5-0.5
Glucose0.81.13.80.50.50.1-0.50.80.61.10.91.9-2.0
Heart weight0.50.81.1-0.9-0.90.91.0-1.00.7-1.0-1.0-0.60.6
Delay discount hyperbolic model param0.10.10.10.40.30.0-0.4-0.20.10.2-0.10.2-0.2
Intermittent access intake day 1-15 change1.41.42.3-1.3-1.41.11.5-0.70.9-1.5-0.8-1.11.1
Intermittent access intake escalation1.01.01.5-1.0-1.11.01.2-0.80.8-1.2-0.9-0.80.8
Intermittent access intake escalation 23.63.56.3-1.6-1.81.21.9-1.50.6-2.4-1.7-2.52.5
Intermitt. access day 1 inactive lever presses0.91.03.2-0.9-0.81.30.7-0.41.8-0.0-0.41.2-1.2
Intermitt. access day 15 inactive lever presses0.91.03.2-0.7-0.71.20.5-0.21.80.3-0.31.4-1.4
Intermitt. access escalation Index0.30.30.80.20.3-0.2-0.1-0.9-0.4-0.4-0.5-0.80.8
Intermittent access day 1 total infusions0.50.61.20.80.80.2-0.6-0.90.70.8-0.51.1-1.1
Intermittent access day 15 total infusions0.70.81.9-0.5-0.61.10.7-1.41.2-0.6-1.2-0.10.1
Intermittent access terminal intake (last 3 days)1.11.22.2-0.7-1.01.31.1-1.51.3-1.0-1.4-0.60.6
Intermittent access total infusions0.60.62.0-0.1-0.31.00.5-1.41.3-0.2-1.10.3-0.3
Intermittent access day 1 locomotion0.50.51.30.30.30.4-0.3-1.10.80.6-0.41.0-1.0
Intermittent access day 15 total locomotion0.20.20.80.20.20.40.0-0.20.70.30.10.9-0.9
Intermittent access total locomotion0.50.61.90.70.6-0.1-0.5-0.00.40.90.51.4-1.4
Intermittent access standard deviation4.34.66.1-2.2-2.41.72.1-2.01.2-2.5-2.2-2.42.4
Left kidney weight2.36.69.3-2.7-2.83.02.9-2.82.8-2.5-2.6-1.51.5
Right kidney weight3.59.912.5-3.5-3.53.53.5-3.23.0-3.2-3.2-2.22.2
Cocaine induced anxiety0.10.10.2-0.4-0.5-0.3-0.00.3-0.4-0.2-0.1-0.40.4
Post-drug Anxiety0.20.30.60.10.1-0.8-0.40.8-0.70.30.70.1-0.1
Baseline Anxiety0.10.10.40.50.6-0.2-0.4-0.1-0.20.50.40.3-0.3
Tail length4.413.318.1-4.3-4.24.24.2-3.43.9-3.5-3.6-2.32.2
Length with tail6.323.232.8-5.6-5.65.75.5-4.65.5-4.5-4.7-2.52.5
Length without tail2.86.19.3-2.9-2.83.12.8-2.53.0-2.2-2.4-1.01.0
Times rat made contact with spout0.40.51.60.70.7-1.0-0.60.7-1.30.20.6-0.30.4
Lifetime Intake0.30.31.00.40.20.5-0.1-1.00.70.3-0.60.6-0.6
Liver weight, left0.00.10.10.30.2-0.3-0.10.2-0.4-0.20.3-0.10.1
Liver weight, right0.00.10.3-0.1-0.10.40.10.00.60.1-0.10.3-0.3
Locomotor activity0.40.71.80.80.8-1.0-0.71.2-1.30.30.9-0.10.1
Locomotor testing distance0.91.43.01.31.3-1.5-1.31.3-1.70.81.20.3-0.3
Locomotor testing rearing1.92.98.91.71.7-2.4-1.51.7-3.00.41.5-0.90.9
Locomotion in novel chamber0.40.51.90.60.7-1.0-0.40.6-1.40.00.9-0.40.4
Locomotion in novel chamber post-restriction0.00.00.10.10.2-0.0-0.20.1-0.00.3-0.00.1-0.1
Fecal boli incidents, locomotor time 13.23.56.31.71.7-1.3-1.81.7-0.72.12.02.5-2.5
Change in fecal boli incidents, locomotor task1.21.13.9-0.3-0.3-0.50.2-0.6-1.1-1.1-0.5-2.02.0
Time >=10cm from walls, locomotor time 10.00.00.10.10.1-0.1-0.20.1-0.00.20.20.2-0.2
Bouts of movement, locomotor time 10.30.30.6-0.7-0.70.00.3-0.4-0.1-0.6-0.0-0.80.7
Total resting periods, locomotor time 10.10.10.3-0.6-0.50.00.1-0.4-0.0-0.30.1-0.40.3
Rest time, locomotor task time 10.10.10.50.20.20.0-0.20.00.20.40.30.7-0.7
Distance moved, locomotor task time 10.20.20.6-0.2-0.30.20.4-0.2-0.0-0.6-0.6-0.70.8
Vertical activity count, locomotor time 11.11.22.1-1.0-1.00.60.8-1.10.4-1.3-1.3-1.41.4
Time >=10cm from walls, locomotor time 20.10.10.3-0.1-0.1-0.10.20.0-0.2-0.30.1-0.50.6
Bouts of movement, locomotor time 20.50.51.80.00.00.30.20.50.60.60.91.3-1.3
Total resting periods, locomotor time 20.40.51.50.10.10.10.10.50.40.61.01.2-1.2
Rest time, locomotor task time 20.10.10.4-0.3-0.30.40.0-0.60.5-0.1-0.5-0.10.1
Distance moved, locomotor task time 20.20.20.60.10.1-0.40.20.2-0.7-0.40.1-0.70.8
Vertical activity count, locomotor time 20.50.51.6-0.6-0.6-0.10.6-0.2-0.5-0.9-0.2-1.21.2
Light reinforcement 10.20.31.00.30.3-0.5-0.41.0-0.60.10.70.3-0.3
Light reinforcement 26.58.711.53.03.1-2.5-3.12.8-1.83.43.03.2-3.2
Bone: marrow area1.22.64.0-1.8-1.81.21.8-1.60.7-2.0-1.4-1.71.7
Bone: maximum diameter1.32.43.7-1.7-1.71.91.7-1.71.9-1.3-1.4-0.70.7
Bone: maximum force2.64.45.3-2.3-2.32.02.2-2.31.7-2.2-2.0-2.02.0
Bone: maximum moment3.45.87.3-2.6-2.62.42.6-2.72.0-2.5-2.3-2.22.2
Mean time between licks in bursts0.10.20.5-0.4-0.40.60.4-0.50.7-0.3-0.5-0.10.1
Mean num. licks in bursts1.41.64.5-1.0-1.10.51.1-0.7-0.1-1.6-0.8-2.12.1
Cd content in liver0.70.72.40.60.6-1.2-0.70.6-1.60.10.6-0.80.8
Co content in liver1.61.92.51.61.6-1.4-1.61.0-1.11.61.41.3-1.3
Cu content in liver1.21.54.2-1.2-1.21.71.2-1.32.1-0.6-1.30.1-0.1
Fe content in liver0.50.61.50.50.5-0.2-0.60.90.10.90.81.2-1.2
K content in liver0.60.61.5-0.7-0.71.10.8-0.81.2-0.5-0.9-0.00.0
Mg content in liver0.20.20.50.0-0.00.50.1-0.20.70.2-0.30.7-0.7
Mn content in liver0.50.51.2-0.3-0.30.50.6-0.90.1-0.8-0.9-1.01.1
Na content in liver4.95.16.3-2.4-2.52.52.5-2.32.2-2.4-2.4-1.71.7
Rb content in liver0.00.00.1-0.1-0.10.10.10.10.2-0.10.00.2-0.2
Se content in liver2.93.55.12.32.2-2.0-2.02.0-2.01.81.81.0-0.9
Sr content in liver0.70.61.01.01.0-0.8-0.90.4-0.70.90.60.7-0.7
Zn content in liver0.50.51.30.60.6-0.2-0.60.50.11.00.51.1-1.1
Bone: minimum diameter5.610.415.7-3.2-3.22.33.2-3.41.3-3.8-3.1-4.03.9
Time in familiar zone, hab. session 10.40.30.5-0.6-0.60.50.6-0.60.3-0.7-0.4-0.70.7
Time in novel zone, hab. session 10.20.20.20.50.5-0.3-0.40.4-0.30.50.20.3-0.3
Total zone transitions, hab. session 11.11.53.8-0.9-0.90.00.9-0.7-0.7-1.8-0.7-2.02.0
Total locomotion distance, hab. session 13.65.19.3-2.3-2.31.22.2-1.80.4-3.0-1.9-3.13.0
Locomotion velocity, hab. session 11.72.55.2-1.5-1.50.51.4-1.1-0.1-2.2-1.3-2.32.3
Time in familiar zone, hab. session 20.30.30.5-0.7-0.70.50.6-0.50.4-0.6-0.7-0.30.3
Time in novel zone, hab. session 20.50.50.90.80.8-0.6-0.70.9-0.40.80.80.5-0.4
Total zone transitions, hab. session 20.10.10.20.40.4-0.3-0.30.3-0.3-0.00.1-0.20.2
Total locomotion distance, hab. session 20.50.61.4-0.6-0.60.40.7-0.60.2-1.0-0.8-1.21.2
Locomotion velocity, hab. session 20.40.61.4-0.5-0.50.40.6-0.60.2-0.9-0.8-1.21.2
Novel to familiar place preference ratio1.51.63.7-1.2-1.20.81.2-0.70.4-1.4-1.0-1.91.9
Novelty place preference1.31.32.6-1.1-1.20.81.2-0.60.5-1.2-0.9-1.61.6
Time in novel zone, NPP test0.90.92.2-0.9-0.90.60.9-0.40.3-1.0-0.7-1.51.5
Total zone transitions, NPP test0.10.20.40.30.3-0.4-0.30.6-0.40.20.50.4-0.4
Total locomotion distance, NPP test1.72.43.9-1.6-1.61.01.5-1.30.7-1.9-1.4-2.01.9
Locomotion velocity, NPP test2.23.14.6-1.9-1.81.21.8-1.50.9-2.1-1.6-2.12.1
Intraocular pressure0.20.20.80.00.00.0-0.10.20.20.60.50.9-0.9
Delta distance traveled before/after self-admin0.60.71.4-1.2-1.20.91.1-0.60.8-0.7-0.4-0.40.4
Delta ambulatory time before/after self-admin1.21.32.0-1.4-1.41.11.4-1.10.9-1.1-0.9-1.01.0
Parametrial fat weight0.61.11.71.11.1-0.7-1.00.9-0.51.20.91.3-1.3
Pavlov. Cond. lever latency0.10.20.30.30.4-0.5-0.40.5-0.40.50.50.2-0.2
Pavlov. Cond. magazine entry latency0.10.20.50.40.4-0.3-0.40.2-0.20.40.30.7-0.7
Pavlov. Cond. change in total contacts0.00.00.1-0.0-0.00.20.0-0.30.30.1-0.00.2-0.2
Pavlov. Cond. index score0.00.00.10.00.00.10.1-0.30.1-0.2-0.10.2-0.1
Pavlov. Cond. latency score0.00.10.2-0.1-0.10.20.2-0.40.2-0.3-0.30.0-0.0
Pavlov. Cond. lever contacts0.70.81.2-0.9-1.01.11.0-1.11.0-1.0-1.0-0.30.3
Pavlov. Cond. magazine entry number0.10.10.1-0.3-0.30.30.3-0.00.3-0.2-0.1-0.20.2
Pavlov. Cond. intertrial magazine entries0.10.10.20.50.5-0.3-0.40.3-0.20.40.3-0.30.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.1-0.10.30.2-0.60.3-0.3-0.40.1-0.0
Pavlov. Cond. response bias0.10.10.2-0.3-0.30.40.3-0.50.4-0.3-0.40.0-0.0
Pavlov. Cond. lever latency2.63.64.62.22.1-2.0-2.02.1-1.81.92.11.2-1.2
Pavlov. Cond. magazine entry latency1.92.25.9-1.6-1.62.01.5-1.42.4-0.8-1.30.3-0.4
Pavlov. Cond. change in total contacts5.37.39.0-3.0-3.02.72.9-3.02.3-2.9-2.9-2.12.1
Pavlov. Cond. index score2.53.24.9-2.1-2.12.11.9-1.92.2-1.6-1.8-0.60.5
Pavlov. Cond. latency score2.43.05.0-2.0-2.02.11.8-1.82.2-1.5-1.8-0.40.4
Pavlov. Cond. lever contacts2.53.54.5-2.1-2.12.02.0-2.11.8-1.9-2.0-1.21.2
Pavlov. Cond. magazine entry number1.21.43.61.41.4-1.6-1.21.1-1.90.71.0-0.30.3
Pavlov. Cond. intertrial magazine entries0.91.21.71.31.2-0.8-1.21.1-0.51.30.91.3-1.3
Pavlov. Cond. lever-magazine prob. diff.2.93.75.6-2.2-2.22.32.1-2.12.4-1.7-2.0-0.70.6
Pavlov. Cond. response bias2.94.05.1-2.3-2.22.22.1-2.22.1-2.0-2.2-1.11.1
Time in closed arm before self-admin0.30.30.80.80.8-0.7-0.90.0-0.70.4-0.0-0.10.1
Time in closed arm after self-admin0.30.41.0-0.4-0.40.70.3-0.71.0-0.2-0.60.6-0.7
Time in open arm before self-admin1.31.42.2-1.5-1.51.51.5-0.91.4-1.1-0.9-0.60.6
Time in open arm after self-admin0.80.92.0-0.8-0.80.80.9-0.80.3-1.0-0.7-1.41.4
Bone: periosteal estimation1.94.05.1-2.1-2.11.72.1-2.11.2-2.3-1.8-2.12.1
Bone: periosteal perimeter1.72.83.5-1.9-1.91.51.8-1.71.1-1.8-1.5-1.71.6
Bone: post-yield work0.71.01.3-1.1-1.10.81.0-0.90.6-1.0-1.0-1.11.1
Progressive ratio test 1 active lever presses1.41.54.9-0.6-0.51.50.8-2.21.7-0.7-1.80.0-0.0
Progressive ratio test 1 breakpoint1.71.84.7-0.8-0.71.71.1-2.21.8-0.9-1.9-0.20.2
Progressive ratio test 1 inactive lever presses0.60.72.1-0.8-0.71.00.3-1.01.40.1-0.60.8-0.8
Progressive ratio test 2 active lever presses0.80.92.6-0.5-0.51.30.7-1.31.6-0.2-1.00.6-0.6
Progressive ratio test 2 breakpoint0.91.03.1-0.5-0.51.40.7-1.41.8-0.2-1.00.7-0.7
Progressive ratio test 2 inactive lever presses2.32.75.8-1.7-1.72.21.7-2.02.4-1.1-1.7-0.10.1
Incentive Sensitization - Responses0.30.30.8-0.1-0.00.50.20.10.80.30.30.9-0.9
Incentive Sensitization - Breakpoint0.30.30.80.00.10.30.10.40.60.40.50.9-0.9
Sum of active levers in priming session hrs 5-61.61.65.3-0.1-0.1-1.00.20.1-1.7-1.1-0.0-2.32.3
Progressive ratio0.30.30.90.30.1-0.9-0.60.8-1.00.20.8-0.10.1
Food seeking constrained by brief footshock2.83.44.5-1.9-2.01.31.6-2.10.9-2.1-1.9-2.12.1
Seeking ratio, punishment vs. effort1.31.63.1-1.1-1.01.51.2-1.81.5-1.0-1.7-0.60.6
Retroperitoneal fat weight0.92.94.51.81.8-1.5-1.72.1-1.31.72.01.6-1.6
Reaction time number correct0.00.00.10.10.10.20.1-0.40.1-0.2-0.3-0.20.3
Reaction time mean minus median0.10.20.4-0.5-0.40.60.4-0.40.6-0.4-0.50.1-0.1
Reaction time mean minus median AUC0.30.41.4-0.5-0.50.90.6-0.61.2-0.3-0.50.4-0.4
Reaction time num false alarms0.60.91.21.11.1-1.1-1.00.5-1.10.81.10.6-0.5
Reaction time num false alarms AUC0.91.31.81.31.3-1.3-1.20.7-1.31.01.30.7-0.7
Reaction time trials correct on left0.00.00.10.10.10.20.1-0.40.1-0.2-0.3-0.20.3
Reaction time trials on left0.00.00.10.10.10.20.0-0.40.1-0.1-0.3-0.20.2
Reaction time mean0.20.20.90.30.3-0.0-0.30.00.20.50.10.9-1.0
Reaction time mean AUC0.40.51.90.50.5-0.0-0.50.20.40.80.21.4-1.4
Median of all reaction times0.30.41.10.50.5-0.2-0.50.20.00.70.31.0-1.0
Reaction time omissions0.20.20.50.70.7-0.4-0.60.1-0.40.50.20.4-0.4
Reaction time false alarm rate0.81.21.71.11.1-1.2-1.10.9-1.01.11.31.0-1.0
Reaction time premature initiation rate0.00.00.1-0.1-0.1-0.20.00.1-0.3-0.20.1-0.20.2
Reaction time premature initiations0.00.00.10.00.0-0.1-0.0-0.1-0.3-0.2-0.0-0.30.3
Std. dev. reaction times0.10.20.5-0.2-0.20.50.2-0.40.7-0.0-0.40.5-0.5
Reaction time trials completed0.00.00.10.10.10.20.0-0.40.1-0.1-0.3-0.20.2
Reaction time trials AUC0.00.00.10.30.30.0-0.1-0.3-0.0-0.0-0.2-0.10.2
Run reversals in cocaine runway, females1.11.03.60.50.40.2-0.50.50.71.20.71.9-1.9
Run reversals in cocaine runway, males1.31.22.71.51.6-1.2-1.20.9-1.30.90.80.5-0.5
Latency to leave start box in cocaine runway0.10.10.40.00.1-0.10.10.7-0.10.10.40.2-0.2
Latency to leave start box in cocaine runway, F0.40.41.10.60.8-0.7-0.31.1-0.70.50.80.1-0.1
Latency to leave start box in cocaine runway, M0.10.10.2-0.4-0.40.40.1-0.20.4-0.0-0.00.4-0.4
Std. dev. time between licks in bursts0.70.91.2-1.0-1.00.71.0-0.80.6-1.1-0.7-1.11.1
Total sessions with >9 infusions0.20.20.80.90.7-0.2-0.4-0.8-0.20.1-0.4-0.10.1
Short access day 1 total inactive lever presses0.50.51.6-0.8-0.81.00.6-0.71.3-0.3-0.50.4-0.4
Short access day 10 total inactive lever presses0.50.61.4-1.1-1.10.90.5-0.51.2-0.1-0.40.6-0.7
Short access day 1 total infusions0.20.31.00.20.00.60.2-1.00.7-0.2-0.8-0.00.0
Short access day 10 total infusions0.30.30.60.80.7-0.3-0.7-0.4-0.00.6-0.10.6-0.6
Short access total infusions0.30.40.91.00.8-0.2-0.6-0.50.10.7-0.10.8-0.8
Short access day 1 locomotion0.91.01.31.11.1-1.2-1.10.9-1.00.91.10.7-0.6
Short access day 10 total locomotion0.70.72.0-0.8-0.90.90.8-1.41.0-0.6-1.0-0.10.1
Short access total locomotion0.10.10.30.20.2-0.1-0.2-0.60.10.3-0.00.5-0.4
One hour access (0.3 mA shock)1.31.62.9-1.2-1.41.31.3-1.71.3-1.2-1.4-0.60.5
Compulsive drug intake0.60.61.6-0.9-0.80.00.4-0.5-0.4-0.9-0.4-1.31.3
One hour access (shock baseline)0.30.41.2-0.1-0.30.80.4-0.81.1-0.2-0.70.5-0.5
Social response proportion4.04.36.7-1.9-2.02.22.0-2.52.1-1.9-2.6-1.61.6
Social responses0.20.21.0-0.3-0.30.70.3-0.21.00.1-0.40.5-0.5
Social time0.40.50.9-0.9-0.90.40.7-0.20.2-0.8-0.5-0.90.9
Soleus weight0.82.46.71.41.5-2.3-1.51.6-2.60.61.60.0-0.0
Bone: stiffness1.42.23.0-1.5-1.51.21.5-1.60.8-1.6-1.4-1.71.7
Tibialis anterior weight0.10.41.3-0.0-0.0-0.40.1-0.0-0.8-0.6-0.1-1.11.1
Time to tail flick, vehicle, before self-admin0.30.31.1-0.3-0.40.80.5-0.51.0-0.2-0.30.4-0.3
Time to tail flick, vehicle, after self-admin0.20.20.5-0.2-0.20.5-0.1-0.60.70.1-0.50.6-0.6
Time to tail flick, test, before self-admin0.10.10.2-0.1-0.20.30.5-0.10.2-0.4-0.0-0.30.3
Time to tail flick, test, after self-admin0.10.10.2-0.1-0.10.20.1-0.40.4-0.1-0.20.2-0.2
Delta time to tail flick, vehicle, before/after SA0.00.00.2-0.1-0.10.1-0.1-0.40.10.0-0.4-0.00.0
Delta time to tail flick, test, before/after SA0.10.10.10.10.1-0.0-0.3-0.10.20.3-0.20.4-0.3
Tibia length1.74.97.1-2.4-2.42.72.4-2.52.6-2.0-2.3-1.01.0
Ambulatory time before self-admin0.80.81.3-0.8-0.80.80.8-1.00.6-1.0-1.1-0.90.9
Ambulatory time after self-admin4.85.36.8-2.6-2.62.42.5-2.42.2-2.1-2.5-1.71.7
Bone: tissue strength3.93.85.2-2.1-2.12.02.1-2.31.7-1.9-2.1-1.61.6
Total heroin consumption2.93.410.1-1.3-1.30.21.3-1.1-0.8-2.2-1.3-3.23.2
Bone: trabecular number0.20.31.2-0.5-0.50.90.4-0.51.10.0-0.10.2-0.2
Bone: trabecular spacing1.72.23.5-1.5-1.50.91.5-1.30.4-1.9-1.6-1.81.8
Bone: trabecular thickness0.50.61.90.50.50.2-0.40.30.61.00.61.4-1.4
Bone: trabecular tissue density2.33.24.21.91.9-2.0-1.92.0-1.91.72.01.1-1.0
Water consumed over 24 hours0.60.81.1-0.9-0.91.11.0-1.01.0-0.9-1.1-0.30.3
Number of responses in last shaping day1.61.62.2-1.0-1.21.51.3-1.41.3-1.3-1.5-1.01.0