Hub : Genes

Cabp5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Cabp5	0.94	0.04	0.0e+00	0.31	0.36	0.36	0.36	1.7e-35	6.2e-41	7.9e-42	1.2e-41
2	Liver	alternative polyA	NM_001108907.1	0.04	0.03	4.0e-04	0.03	0.02	0.02	0.02	5.8e-04	4.5e-03	6.4e-03	6.4e-03
3	Liver	alternative polyA	XM_063269032.1	0.04	0.03	4.6e-04	0.02	0.02	0.01	0.01	9.2e-04	5.0e-03	7.6e-03	8.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.0	0.0	0.1	0.3	0.1	-0.1
Area under the delay curve	0.2	0.3	0.3	0.4	0.5	-0.5
BMI with tail	1.4	4.8	5.5	-1.9	-2.3	2.3
BMI without tail	1.5	7.8	8.0	-2.7	-2.8	2.8
Body weight	3.1	13.7	15.4	-3.9	-3.6	3.6
Weight adjusted by age	0.2	0.7	1.0	-1.0	-0.7	0.7
Bone surface	0.4	0.8	1.4	-1.2	-0.7	0.7
Bone volume	0.1	0.3	0.5	-0.7	-0.4	0.4
Breakpoint value in progressive ratio session	0.9	1.6	2.1	1.5	1.2	-1.2
Number of licking bursts	0.7	2.1	2.3	-1.5	-1.4	1.4
Context. condit. distance diff. score	0.1	0.1	0.2	-0.4	-0.3	0.3
Locomotion velocity, session 1	0.8	0.9	1.1	0.7	1.0	-1.0
Locomotion distance, session 1	0.2	0.2	0.3	-0.2	0.5	-0.5
Locomotion velocity, session 2	0.6	0.7	1.4	-1.2	-0.6	0.6
Locomotion distance, session 2	0.7	1.0	2.5	-1.6	-0.5	0.5
Locomotion velocity, session 3	0.1	0.2	0.2	-0.4	-0.4	0.4
Locomotion distance, session 3	0.1	0.1	0.2	-0.0	0.4	-0.4
Stereotopy head waving bouts, day 3	0.1	0.2	0.2	-0.2	-0.5	0.5
Stereotopy head waving duration, day 3	0.0	0.0	0.0	0.1	-0.1	0.1
Locomotion velocity, session 7	1.8	2.0	2.2	1.2	1.5	-1.5
Locomotion distance, session 7	0.1	0.2	0.2	0.2	0.5	-0.5
Stereotopy head waving bouts, day 7	0.4	0.4	0.7	-0.8	-0.5	0.5
Stereotopy head waving duration, day 7	0.3	0.4	0.6	-0.8	-0.5	0.5
Locomotion velocity, session 8	0.0	0.1	0.1	0.2	0.2	-0.2
Locomotion distance, session 8	0.2	0.3	0.7	-0.8	-0.2	0.2
Degree of sensitization distance	0.0	0.0	0.0	0.1	-0.1	0.1
Degree of sensitization stereotypy	0.9	1.0	1.8	-1.3	-0.8	0.8
Conditioned locomotion	0.1	0.1	0.2	-0.4	-0.1	0.1
Cocaine response after cond. corrected	0.1	0.1	0.1	0.2	-0.3	0.3
Cocaine response after cond. not corrected	0.4	0.6	0.7	-0.8	-0.8	0.8
Cocaine response before conditioning	2.9	3.5	5.8	-2.4	-1.6	1.6
Saline control response	1.3	1.7	2.3	-1.5	-1.2	1.2
Bone: connectivity density	0.0	0.0	0.0	0.0	-0.2	0.2
Bone: cortical apparent density	0.2	0.4	0.4	0.5	0.7	-0.7
Bone: cortical area	0.7	1.1	2.3	-1.5	-0.7	0.7
Bone: cortical porosity	0.3	0.3	0.5	-0.0	-0.7	0.7
Bone: cortical porosity	0.7	0.8	1.1	-0.4	-1.0	1.0
Bone: cortical thickness	0.0	0.0	0.0	-0.1	-0.1	0.1
Bone: cortical thickness	0.3	0.4	0.5	-0.6	-0.7	0.7
Bone: cortical tissue density	0.3	0.5	0.5	0.6	0.7	-0.7
Condit. Reinf. active minus inactive responses	0.8	0.9	1.0	-0.8	-1.0	1.0
Condit. Reinf. active-inactive response ratio	0.9	1.0	1.1	-0.8	-1.0	1.0
Condit. Reinf. active responses	0.4	0.5	0.5	-0.7	-0.7	0.7
Condit. Reinf. inactive responses	0.2	0.3	0.4	0.3	0.6	-0.6
Incentive salience index mean	0.7	0.9	0.9	-1.0	-1.0	1.0
Condit. Reinf. lever presses	0.4	0.6	0.7	-0.8	-0.8	0.8
Condit. Reinf. active minus inactive responses	0.3	0.4	0.5	-0.3	0.7	-0.7
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.4	-0.3	0.7	-0.7
Condit. Reinf. active responses	0.2	0.3	0.4	-0.3	0.7	-0.7
Condit. Reinf. inactive responses	0.0	0.0	0.0	0.2	-0.0	0.0
Condit. Reinf. lever presses	0.3	0.4	0.8	-0.9	-0.5	0.5
Condit. Reinf. lever reinforcers received	0.2	0.3	0.3	-0.5	0.5	-0.5
Conditioned reinforcement - actives	0.7	2.7	2.7	-1.6	-1.7	1.7
Conditioned reinforcement - inactives	0.1	0.4	0.7	-0.9	-0.4	0.4
Conditioned locomotion	0.4	0.6	0.7	-0.8	-0.7	0.7
Patch foraging indifference point 0 sec	0.0	0.1	0.1	0.1	-0.3	0.3
Patch foraging indifference point AUC	2.2	5.3	5.6	-2.2	-2.4	2.4
Delay disc. indifference point, 0s delay	0.3	0.3	0.4	0.3	0.6	-0.6
Delay disc. indifference point, 16s delay	0.3	0.4	0.7	0.9	0.5	-0.5
Delay disc. indifference point, 2s delay	0.4	0.4	0.4	0.6	0.7	-0.7
Delay disc. indifference point, 24s delay	0.2	0.2	0.4	-0.0	-0.6	0.6
Delay disc. indifference point, 4s delay	0.2	0.2	0.5	-0.7	-0.2	0.2
Delay disc. indifference point, 8s delay	0.4	0.7	0.8	0.7	0.9	-0.9
Indifference point function ln k	1.5	4.6	5.5	1.7	2.3	-2.3
Indifference point function log k	1.5	4.6	5.5	1.7	2.3	-2.3
Patch foraging total patch changes 0 sec	0.0	0.1	0.2	-0.0	-0.5	0.5
Patch foraging total patch changes 12 sec	1.7	2.2	2.5	-1.3	-1.6	1.6
Patch foraging total patch changes 18 sec	1.2	2.8	3.1	-1.5	-1.8	1.8
Patch foraging total patch changes 24 sec	0.8	2.9	2.9	-1.7	-1.7	1.7
Patch foraging total patch changes 6 sec	1.1	1.9	2.4	-1.0	-1.6	1.6
Patch foraging time to switch 0 sec	0.6	2.5	4.8	2.2	1.2	-1.2
Patch foraging water rate 0 sec	0.7	2.6	3.6	-1.9	-1.4	1.4
Patch foraging water rate 12 sec	0.0	0.1	0.2	-0.2	0.4	-0.4
Patch foraging water rate 18 sec	0.1	0.2	0.2	0.3	0.4	-0.4
Patch foraging water rate 24 sec	0.1	0.2	0.3	0.2	0.5	-0.5
Patch foraging water rate 6 sec	2.6	3.8	6.7	-2.6	-1.5	1.5
Seeking ratio, delayed vs. immediate footshock	1.4	2.0	2.1	1.4	1.4	-1.4
Distance traveled before self-admin	0.1	0.1	0.1	-0.4	0.4	-0.4
Distance traveled after self-admin	0.6	1.1	1.2	1.0	1.1	-1.1
Extensor digitorum longus weight	2.0	7.9	8.4	-2.9	-2.8	2.8
Bone: elastic displacement	2.3	2.9	4.0	2.0	1.5	-1.5
Bone: elastic work	0.2	0.3	0.3	0.5	0.6	-0.6
Bone: endosteal estimation	0.1	0.3	0.8	-0.9	-0.1	0.1
Bone: endosteal perimeter	0.1	0.2	0.5	-0.7	0.1	-0.1
Epididymis fat weight	0.1	0.8	1.3	1.1	0.7	-0.7
Delta time in closed arm before/after self-admin	0.0	0.0	0.0	0.2	0.2	-0.2
Delta time in open arm before/after self-admin	0.2	0.3	0.5	-0.7	-0.4	0.4
Diff in mean of infusions in LGA sessions	0.4	0.7	0.9	0.5	1.0	-1.0
Delay discount exponential model param	0.1	0.1	0.1	-0.3	-0.4	0.4
Extinction: sum of active levers before priming	0.0	0.0	0.1	-0.3	-0.0	0.0
Active lever presses in extinction session 6	2.5	2.5	2.6	-1.5	-1.6	1.6
Bone: final force	1.1	1.7	3.2	-1.8	-1.0	1.0
Bone: final moment	1.1	1.8	3.7	-1.9	-1.0	1.0
Food consumed during 24 hour testing period	2.1	4.1	4.6	1.8	2.1	-2.1
Glucose	1.8	2.9	4.4	2.1	1.5	-1.5
Heart weight	0.8	1.3	1.7	-0.7	-1.3	1.3
Delay discount hyperbolic model param	0.0	0.1	0.1	-0.1	-0.3	0.3
Intermittent access intake day 1-15 change	0.1	0.7	0.7	-0.9	-0.9	0.9
Intermittent access intake escalation	0.2	1.2	1.3	-1.1	-1.1	1.1
Intermittent access intake escalation 2	0.0	0.1	0.1	-0.3	-0.2	0.2
Intermitt. access day 1 inactive lever presses	0.0	0.3	0.4	-0.2	-0.7	0.7
Intermitt. access day 15 inactive lever presses	0.2	1.1	1.6	-1.3	-0.9	0.9
Intermitt. access escalation Index	0.0	0.1	0.1	0.0	-0.3	0.3
Intermittent access day 1 total infusions	0.3	0.8	0.9	-0.9	-0.9	0.9
Intermittent access day 15 total infusions	0.4	0.9	1.0	-0.9	-1.0	1.0
Intermittent access terminal intake (last 3 days)	0.3	0.5	0.5	-0.7	-0.7	0.7
Intermittent access total infusions	0.9	1.1	1.2	-1.1	-1.0	1.0
Intermittent access day 1 locomotion	0.1	0.1	0.2	0.1	0.4	-0.4
Intermittent access day 15 total locomotion	0.0	0.1	0.1	0.1	0.3	-0.3
Intermittent access total locomotion	0.0	0.0	0.1	-0.3	0.0	-0.0
Intermittent access standard deviation	0.0	0.1	0.2	0.4	-0.2	0.2
Left kidney weight	3.2	25.7	34.2	-5.8	-4.6	4.6
Right kidney weight	2.8	19.7	27.1	-5.2	-4.0	4.0
Cocaine induced anxiety	0.2	0.5	0.6	0.4	0.8	-0.8
Post-drug Anxiety	0.3	0.4	0.4	0.5	0.7	-0.7
Baseline Anxiety	0.6	1.0	1.4	1.2	0.9	-0.9
Tail length	1.2	6.6	9.6	-3.1	-2.3	2.3
Length with tail	1.1	5.0	7.4	-2.7	-2.0	2.0
Length without tail	0.3	1.8	2.5	-1.6	-1.2	1.2
Times rat made contact with spout	0.6	0.7	0.9	0.7	0.9	-0.9
Lifetime Intake	1.4	1.7	1.7	-1.3	-1.3	1.3
Liver weight, left	6.4	11.1	13.6	-3.7	-3.1	3.1
Liver weight, right	2.1	3.7	3.9	-2.0	-1.9	1.9
Locomotor activity	2.2	3.4	3.6	-1.7	-1.9	1.9
Locomotor testing distance	1.2	3.0	3.2	-1.6	-1.8	1.8
Locomotor testing rearing	3.0	10.9	12.0	-3.5	-3.2	3.2
Locomotion in novel chamber	3.0	4.1	4.4	2.1	2.0	-2.0
Locomotion in novel chamber post-restriction	0.4	1.1	1.2	1.1	1.0	-1.0
Fecal boli incidents, locomotor time 1	0.0	0.0	0.0	-0.0	0.1	-0.1
Change in fecal boli incidents, locomotor task	0.6	0.7	0.9	1.0	0.7	-0.7
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	0.0	0.2	-0.2
Bouts of movement, locomotor time 1	1.0	1.3	1.5	1.0	1.2	-1.2
Total resting periods, locomotor time 1	2.5	2.9	2.9	1.7	1.7	-1.7
Rest time, locomotor task time 1	0.3	0.5	0.5	0.6	0.7	-0.7
Distance moved, locomotor task time 1	0.3	0.9	0.9	-1.0	-0.9	0.9
Vertical activity count, locomotor time 1	0.0	0.3	0.3	-0.6	-0.5	0.5
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.0	-0.0	0.0	-0.0
Bouts of movement, locomotor time 2	0.9	2.9	2.9	1.7	1.7	-1.7
Total resting periods, locomotor time 2	0.9	3.5	3.6	1.9	1.9	-1.9
Rest time, locomotor task time 2	1.3	2.1	2.6	1.6	1.4	-1.4
Distance moved, locomotor task time 2	1.8	2.4	2.7	-1.6	-1.5	1.5
Vertical activity count, locomotor time 2	0.6	1.5	1.8	-1.3	-1.1	1.1
Light reinforcement 1	0.2	0.9	1.4	-1.2	-0.8	0.8
Light reinforcement 2	0.6	1.3	1.4	-1.0	-1.2	1.2
Bone: marrow area	0.1	0.4	1.0	-1.0	-0.2	0.2
Bone: maximum diameter	2.5	4.9	7.3	-2.7	-1.9	1.9
Bone: maximum force	0.4	0.8	1.6	-1.3	-0.6	0.6
Bone: maximum moment	0.4	0.8	1.9	-1.4	-0.5	0.5
Mean time between licks in bursts	0.0	0.2	0.3	-0.5	-0.4	0.4
Mean num. licks in bursts	1.5	4.0	4.1	1.9	2.0	-2.0
Cd content in liver	0.5	0.5	0.7	0.4	0.9	-0.9
Co content in liver	0.4	0.4	0.4	0.6	0.7	-0.7
Cu content in liver	1.4	1.7	1.8	-1.3	-1.3	1.3
Fe content in liver	3.7	4.5	4.9	-2.2	-2.1	2.1
K content in liver	2.0	2.0	2.2	-1.2	-1.5	1.5
Mg content in liver	2.2	2.5	2.6	-1.5	-1.6	1.6
Mn content in liver	0.7	0.7	0.9	-0.6	-0.9	0.9
Na content in liver	0.6	0.6	0.9	-0.3	-0.9	0.9
Rb content in liver	0.3	0.4	0.8	-0.9	-0.4	0.4
Se content in liver	8.6	10.1	10.8	-3.0	-3.3	3.3
Sr content in liver	0.4	0.3	0.7	0.8	0.4	-0.4
Zn content in liver	2.4	2.8	3.2	-1.8	-1.6	1.6
Bone: minimum diameter	0.4	0.8	2.2	-1.5	-0.3	0.3
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.4	0.2	-0.2
Time in novel zone, hab. session 1	0.9	1.0	1.2	-0.8	-1.1	1.1
Total zone transitions, hab. session 1	0.1	0.1	0.3	-0.5	0.2	-0.2
Total locomotion distance, hab. session 1	0.5	0.7	1.0	0.4	1.0	-1.0
Locomotion velocity, hab. session 1	1.3	1.8	2.2	1.0	1.5	-1.5
Time in familiar zone, hab. session 2	0.1	0.1	0.1	0.1	0.4	-0.4
Time in novel zone, hab. session 2	0.1	0.2	0.2	-0.4	-0.4	0.4
Total zone transitions, hab. session 2	0.4	0.5	1.2	-1.1	-0.4	0.4
Total locomotion distance, hab. session 2	0.6	0.7	0.9	0.6	0.9	-0.9
Locomotion velocity, hab. session 2	0.3	0.4	0.5	0.4	0.7	-0.7
Novel to familiar place preference ratio	0.5	0.7	1.1	-1.1	-0.7	0.7
Novelty place preference	0.4	0.5	1.0	-1.0	-0.5	0.5
Time in novel zone, NPP test	0.5	0.6	1.1	-1.0	-0.6	0.6
Total zone transitions, NPP test	0.1	0.2	0.4	-0.7	-0.3	0.3
Total locomotion distance, NPP test	0.0	0.1	0.1	-0.4	-0.1	0.1
Locomotion velocity, NPP test	0.1	0.1	0.2	-0.4	-0.1	0.1
Intraocular pressure	0.2	0.3	0.4	0.3	0.6	-0.6
Delta distance traveled before/after self-admin	0.3	0.4	0.9	1.0	0.3	-0.3
Delta ambulatory time before/after self-admin	0.2	0.4	1.0	1.0	0.3	-0.3
Parametrial fat weight	0.3	0.8	2.0	1.4	0.4	-0.4
Pavlov. Cond. lever latency	1.2	1.5	1.6	1.2	1.3	-1.3
Pavlov. Cond. magazine entry latency	1.3	1.7	2.0	-1.1	-1.4	1.4
Pavlov. Cond. change in total contacts	0.0	0.0	0.0	0.1	-0.1	0.1
Pavlov. Cond. index score	1.8	2.2	2.4	-1.4	-1.6	1.6
Pavlov. Cond. latency score	0.9	1.2	1.4	-0.9	-1.2	1.2
Pavlov. Cond. lever contacts	0.9	1.1	1.1	-1.0	-1.1	1.1
Pavlov. Cond. magazine entry number	1.2	1.5	1.7	1.1	1.3	-1.3
Pavlov. Cond. intertrial magazine entries	0.4	0.5	0.6	0.6	0.8	-0.8
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.3	2.4	-1.4	-1.6	1.6
Pavlov. Cond. response bias	3.0	3.7	3.8	-1.9	-1.9	1.9
Pavlov. Cond. lever latency	0.1	0.1	0.1	0.3	0.3	-0.3
Pavlov. Cond. magazine entry latency	0.0	0.0	0.1	-0.0	-0.2	0.2
Pavlov. Cond. change in total contacts	0.2	0.5	0.6	0.6	0.8	-0.8
Pavlov. Cond. index score	0.0	0.0	0.0	-0.1	-0.1	0.1
Pavlov. Cond. latency score	0.0	0.0	0.1	0.2	0.0	-0.0
Pavlov. Cond. lever contacts	0.2	0.3	0.3	-0.6	-0.5	0.5
Pavlov. Cond. magazine entry number	0.2	0.2	0.3	-0.5	-0.4	0.4
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.5	-0.7	-0.1	0.1
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.1	-0.3	-0.3	0.3
Pavlov. Cond. response bias	0.1	0.1	0.2	-0.5	-0.2	0.2
Time in closed arm before self-admin	0.0	0.1	0.1	-0.3	-0.3	0.3
Time in closed arm after self-admin	0.3	0.4	0.5	0.7	0.6	-0.6
Time in open arm before self-admin	0.1	0.1	0.2	0.4	0.3	-0.3
Time in open arm after self-admin	0.0	0.0	0.0	0.0	-0.0	0.0
Bone: periosteal estimation	0.4	1.0	2.4	-1.6	-0.6	0.6
Bone: periosteal perimeter	0.4	0.7	1.8	-1.4	-0.4	0.4
Bone: post-yield work	0.1	0.2	0.3	-0.1	0.5	-0.5
Progressive ratio test 1 active lever presses	0.5	0.8	1.2	-1.1	-0.8	0.8
Progressive ratio test 1 breakpoint	0.4	0.7	1.0	-1.0	-0.7	0.7
Progressive ratio test 1 inactive lever presses	0.8	2.1	3.2	-1.8	-1.2	1.2
Progressive ratio test 2 active lever presses	1.6	2.3	2.5	-1.4	-1.6	1.6
Progressive ratio test 2 breakpoint	2.0	2.5	2.7	-1.5	-1.7	1.7
Progressive ratio test 2 inactive lever presses	0.6	1.8	3.0	-1.7	-1.1	1.1
Incentive Sensitization - Responses	0.5	1.5	1.6	-1.1	-1.3	1.3
Incentive Sensitization - Breakpoint	0.7	1.6	1.7	-1.1	-1.3	1.3
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.4	0.5	0.6	-0.6
Progressive ratio	0.1	0.2	0.2	0.5	0.4	-0.4
Food seeking constrained by brief footshock	2.2	2.7	3.5	1.1	1.9	-1.9
Seeking ratio, punishment vs. effort	0.2	0.4	0.6	0.2	0.8	-0.8
Retroperitoneal fat weight	0.2	1.1	3.1	1.8	0.2	-0.2
Reaction time number correct	0.7	2.7	2.8	-1.7	-1.6	1.6
Reaction time mean minus median	0.1	0.8	0.9	0.8	0.9	-0.9
Reaction time mean minus median AUC	0.0	0.0	0.1	0.1	0.2	-0.2
Reaction time num false alarms	4.9	8.4	8.5	-2.9	-2.9	2.9
Reaction time num false alarms AUC	2.9	6.6	6.6	-2.6	-2.6	2.6
Reaction time trials correct on left	0.7	2.7	2.8	-1.7	-1.6	1.6
Reaction time trials on left	0.8	2.7	2.8	-1.7	-1.6	1.6
Reaction time mean	1.0	2.3	2.3	1.5	1.5	-1.5
Reaction time mean AUC	0.8	1.9	2.0	1.4	1.4	-1.4
Median of all reaction times	1.2	1.8	1.9	1.3	1.4	-1.4
Reaction time omissions	0.1	0.1	0.1	-0.1	0.4	-0.4
Reaction time false alarm rate	0.9	1.2	1.3	-1.1	-1.1	1.1
Reaction time premature initiation rate	2.2	3.5	4.0	2.0	1.8	-1.8
Reaction time premature initiations	0.3	1.0	1.3	1.1	0.9	-0.9
Std. dev. reaction times	0.4	1.3	1.4	1.0	1.2	-1.2
Reaction time trials completed	0.8	2.7	2.8	-1.7	-1.6	1.6
Reaction time trials AUC	0.9	3.3	3.4	-1.8	-1.8	1.8
Run reversals in cocaine runway, females	2.1	2.4	2.5	1.6	1.5	-1.5
Run reversals in cocaine runway, males	0.9	1.0	1.5	-1.2	-0.8	0.8
Latency to leave start box in cocaine runway	0.5	0.7	1.3	1.2	0.6	-0.6
Latency to leave start box in cocaine runway, F	0.3	0.3	0.8	0.9	0.3	-0.3
Latency to leave start box in cocaine runway, M	0.0	0.0	0.0	0.0	-0.1	0.1
Std. dev. time between licks in bursts	0.7	1.4	1.6	-1.3	-1.1	1.1
Total sessions with >9 infusions	1.7	2.2	3.0	-1.7	-1.3	1.3
Short access day 1 total inactive lever presses	1.1	2.3	2.8	-1.7	-1.4	1.4
Short access day 10 total inactive lever presses	0.2	1.1	1.1	1.0	1.0	-1.0
Short access day 1 total infusions	0.7	1.4	1.4	-1.2	-1.2	1.2
Short access day 10 total infusions	2.4	3.9	4.1	-1.9	-2.0	2.0
Short access total infusions	1.7	2.4	2.5	-1.5	-1.6	1.6
Short access day 1 locomotion	1.8	3.0	4.2	-2.0	-1.6	1.6
Short access day 10 total locomotion	0.3	1.1	1.4	0.8	1.2	-1.2
Short access total locomotion	0.0	0.1	0.2	-0.4	-0.0	0.0
One hour access (0.3 mA shock)	0.0	0.0	0.0	-0.1	-0.0	0.0
Compulsive drug intake	0.0	0.0	0.0	-0.1	-0.2	0.2
One hour access (shock baseline)	0.3	0.8	0.9	-0.8	-0.9	0.9
Social response proportion	0.6	0.7	1.2	-1.1	-0.7	0.7
Social responses	1.6	2.1	4.3	-2.1	-1.0	1.0
Social time	0.1	0.2	0.3	-0.3	0.6	-0.6
Soleus weight	0.5	1.6	1.7	-1.1	-1.3	1.3
Bone: stiffness	1.8	3.4	4.6	-2.2	-1.6	1.6
Tibialis anterior weight	3.4	11.6	12.6	-3.1	-3.5	3.5
Time to tail flick, vehicle, before self-admin	0.0	0.0	0.0	0.1	-0.1	0.1
Time to tail flick, vehicle, after self-admin	0.2	0.3	0.4	0.4	0.6	-0.6
Time to tail flick, test, before self-admin	1.4	1.6	1.9	1.0	1.4	-1.4
Time to tail flick, test, after self-admin	0.2	0.2	0.5	0.7	0.2	-0.2
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	-0.1	0.3	-0.3
Delta time to tail flick, test, before/after SA	0.3	0.4	0.6	-0.4	-0.8	0.8
Tibia length	1.9	5.3	7.7	-2.8	-2.0	2.0
Ambulatory time before self-admin	0.1	0.2	0.2	-0.5	0.4	-0.4
Ambulatory time after self-admin	0.7	1.0	1.1	1.0	1.1	-1.1
Bone: tissue strength	0.2	0.2	0.3	0.4	0.5	-0.5
Total heroin consumption	0.2	0.3	0.7	-0.9	-0.2	0.2
Bone: trabecular number	0.0	0.0	0.1	0.4	0.0	-0.0
Bone: trabecular spacing	0.0	0.0	0.0	-0.1	-0.0	0.0
Bone: trabecular thickness	0.5	0.7	0.8	-0.7	-0.9	0.9
Bone: trabecular tissue density	0.1	0.2	0.2	0.2	-0.5	0.5
Water consumed over 24 hours	0.4	0.8	1.0	0.7	1.0	-1.0
Number of responses in last shaping day	2.2	2.8	3.1	-1.5	-1.8	1.8