Hub : Genes

C9h2orf88

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression C9h2orf88 0.04 0.03 8.8e-05 0.01 0.01 0.01 0 3.4e-02 1.6e-02 2.3e-02 9.6e-02
2 pVTA intron excision ratio chr9_56051719_56076002 0.28 0.14 5.6e-17 0.21 0.2 0.21 0.22 4.7e-17 3.2e-16 1.5e-16 3.5e-17
3 Liver gene expression C9h2orf88 0.03 0.02 1.1e-03 0.01 0.01 -0 0.01 3.2e-02 7.6e-03 7.9e-01 3.8e-02
4 NAcc gene expression C9h2orf88 0.05 0.03 1.8e-06 0.04 0.02 0.04 0.04 3.4e-07 1.2e-04 1.2e-06 1.3e-06
5 Brain intron excision ratio chr9_56051719_56076002 0.17 0.1 1.1e-13 0.15 0.14 0.14 0.14 1.0e-13 4.8e-13 4.4e-13 2.9e-13
6 NAcc intron excision ratio chr9_56051719_56076002 0.09 0.06 6.8e-08 0.03 0.04 0.04 0.04 7.9e-05 4.0e-07 4.1e-07 2.0e-07
7 pVTA gene expression C9h2orf88 0.07 0.05 7.7e-05 0.04 0.04 0.04 0.04 3.8e-04 4.8e-04 6.8e-04 8.3e-04
8 IC gene expression C9h2orf88 0.3 0.11 1.7e-09 0.19 0.17 0.17 0.17 2.7e-08 1.6e-07 1.6e-07 1.2e-07
9 IC intron excision ratio chr9_56051719_56076002 0.27 0.2 2.3e-03 0.02 0.03 0.02 0.03 6.3e-02 1.6e-02 3.5e-02 3.2e-02
10 pVTA intron excision ratio chr9_56052293_56076002 0.09 0.05 1.2e-05 0.04 0.07 0.06 0.06 2.2e-04 4.7e-06 8.1e-06 9.0e-06
11 Brain mRNA stability C9h2orf88 0.07 0.04 4.0e-06 0.06 0.06 0.05 0.06 2.6e-06 1.6e-06 2.2e-05 3.7e-06
12 Brain intron excision ratio chr9_56052293_56076002 0.07 0.04 2.7e-05 0.04 0.06 0.06 0.06 9.0e-05 7.7e-06 4.3e-06 6.0e-06
13 NAcc intron excision ratio chr9_56052293_56076002 0.06 0.04 8.0e-08 0.03 0.04 0.04 0.04 7.8e-06 2.1e-07 3.0e-06 7.1e-07
14 PL intron excision ratio chr9_56052293_56076002 0.04 0.03 5.4e-03 0 0.02 0.01 0.01 1.1e-01 6.3e-03 1.4e-02 2.2e-02
15 PL mRNA stability C9h2orf88 0.06 0.04 2.4e-05 0.04 0.04 0.04 0.04 6.2e-05 1.7e-05 2.4e-05 1.7e-05
16 OFC gene expression C9h2orf88 0.5 0.19 1.7e-03 0.1 0.12 0.09 0.09 2.5e-03 8.2e-04 4.3e-03 3.8e-03
17 PL gene expression C9h2orf88 0.34 0.13 0.0e+00 0.18 0.24 0.25 0.25 8.8e-20 5.5e-26 1.2e-26 1.2e-26
18 Brain gene expression C9h2orf88 0.15 0.08 1.1e-10 0.1 0.11 0.11 0.1 3.0e-09 8.4e-11 3.3e-10 5.5e-10
19 BLA gene expression C9h2orf88 0.15 0.1 1.7e-04 0.02 0.04 0.03 0.04 1.9e-02 3.1e-03 6.2e-03 3.2e-03
20 IC intron excision ratio chr9_56052293_56076002 0.14 0.08 5.7e-04 0.03 0.05 0.05 0.05 1.5e-02 2.8e-03 4.5e-03 3.3e-03
21 IL gene expression C9h2orf88 0.31 0.15 2.8e-04 0.18 0.16 0.2 0.2 4.8e-05 1.1e-04 1.6e-05 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.52.75.02.21.71.61.6-2.01.91.91.91.7-1.9-1.91.6-1.7-1.9-1.4-0.2-1.3-1.3-1.5-0.70.9
Area under the delay curve0.00.00.20.0-0.0-0.00.20.00.10.10.10.2-0.1-0.1-0.0-0.1-0.0-0.0-0.4-0.0-0.10.0-0.10.3
BMI with tail1.55.119.7-4.0-3.5-4.4-3.23.1-2.6-2.5-2.5-1.81.91.8-1.71.31.40.5-1.10.40.00.3-1.11.1
BMI without tail0.31.45.1-1.0-0.5-2.2-0.50.20.10.10.20.7-0.5-0.60.7-0.9-0.7-1.3-2.1-1.4-1.4-1.2-2.01.9
Body weight0.00.00.10.10.00.30.10.20.10.20.2-0.00.10.2-0.20.20.30.1-0.2-0.10.30.40.2-0.3
Weight adjusted by age0.51.33.50.3-0.31.5-0.10.5-0.5-0.7-0.7-0.90.90.9-1.11.11.01.41.91.61.51.31.8-1.8
Bone surface0.20.42.10.60.11.20.10.1-0.00.0-0.0-0.40.20.2-0.50.40.20.61.40.60.60.41.0-0.8
Bone volume0.50.93.61.81.21.91.1-1.11.11.21.10.6-0.9-0.90.5-0.6-0.9-0.30.9-0.3-0.2-0.40.4-0.3
Breakpoint value in progressive ratio session0.91.72.71.51.30.91.4-1.61.51.61.61.6-1.4-1.31.4-1.3-1.1-1.2-1.4-1.2-1.0-0.8-0.80.6
Number of licking bursts0.61.93.30.30.9-0.90.9-1.11.01.01.01.5-1.3-1.41.6-1.5-1.4-1.7-1.8-1.7-1.7-1.6-1.81.7
Context. condit. distance diff. score2.02.48.6-0.30.0-1.8-0.0-0.80.70.70.71.6-1.2-1.21.5-1.5-1.2-1.8-2.9-1.9-1.9-1.5-2.42.5
Locomotion velocity, session 10.10.10.5-0.0-0.0-0.3-0.1-0.30.30.30.30.3-0.2-0.20.5-0.3-0.1-0.5-0.7-0.5-0.3-0.2-0.40.4
Locomotion distance, session 10.40.51.4-0.7-1.1-0.4-1.20.6-0.8-0.8-0.9-0.60.70.7-0.40.70.80.60.10.70.60.70.4-0.3
Locomotion velocity, session 21.72.13.6-1.7-1.9-1.1-1.91.7-1.6-1.6-1.5-1.71.61.6-1.41.51.51.30.81.21.21.20.8-0.7
Locomotion distance, session 21.42.02.8-1.4-1.4-0.6-1.41.5-1.6-1.6-1.7-1.51.61.6-1.51.51.51.41.01.51.31.41.1-1.1
Locomotion velocity, session 30.00.10.3-0.4-0.3-0.5-0.20.2-0.3-0.4-0.4-0.10.10.1-0.10.10.10.1-0.20.1-0.1-0.0-0.20.2
Locomotion distance, session 30.30.40.9-0.20.6-0.80.6-0.20.00.0-0.00.5-0.4-0.50.4-0.6-0.6-0.6-0.8-0.7-0.8-0.8-0.90.9
Stereotopy head waving bouts, day 30.40.51.3-0.9-1.1-0.7-1.10.8-0.8-0.7-0.8-0.70.70.7-0.60.60.70.50.10.50.40.50.2-0.1
Stereotopy head waving duration, day 30.00.10.5-0.1-0.7-0.1-0.70.00.10.10.1-0.00.10.10.00.10.1-0.0-0.3-0.00.00.1-0.10.2
Locomotion velocity, session 72.22.53.5-0.9-1.10.3-1.01.5-1.5-1.5-1.5-1.71.71.7-1.81.71.71.81.61.81.81.81.7-1.9
Locomotion distance, session 71.31.72.5-0.8-0.70.1-0.61.3-1.3-1.3-1.3-1.31.41.4-1.51.51.51.41.01.41.51.61.4-1.6
Stereotopy head waving bouts, day 70.40.50.70.70.70.30.7-0.70.80.70.80.9-0.8-0.70.6-0.8-0.7-0.7-0.7-0.6-0.6-0.6-0.60.6
Stereotopy head waving duration, day 70.40.50.91.00.70.70.7-0.80.90.80.90.8-0.8-0.80.6-0.7-0.7-0.5-0.2-0.4-0.5-0.5-0.30.3
Locomotion velocity, session 80.20.31.2-0.3-0.1-0.8-0.1-0.10.0-0.0-0.00.4-0.3-0.40.5-0.5-0.4-0.5-0.7-0.5-0.7-0.6-0.81.1
Locomotion distance, session 80.40.63.0-1.2-0.9-1.7-1.00.5-0.6-0.6-0.60.10.20.20.0-0.10.1-0.3-1.2-0.4-0.5-0.3-1.01.2
Degree of sensitization distance1.71.83.6-0.2-0.81.0-0.81.0-0.9-0.8-0.8-1.31.31.4-1.41.51.51.61.51.61.81.81.9-1.9
Degree of sensitization stereotypy0.60.70.90.70.90.20.9-0.90.80.80.81.0-0.9-0.90.8-0.9-0.9-0.8-0.7-0.7-0.8-0.8-0.70.8
Conditioned locomotion0.00.00.30.00.20.10.20.00.00.10.10.10.10.2-0.00.10.3-0.0-0.5-0.10.20.40.1-0.2
Cocaine response after cond. corrected1.21.82.9-0.7-0.90.4-1.01.1-1.3-1.4-1.3-1.31.41.5-1.31.51.61.61.21.61.61.71.6-1.3
Cocaine response after cond. not corrected1.82.65.3-0.0-0.61.5-0.70.8-1.1-1.2-1.1-1.51.51.5-1.41.71.72.12.02.12.12.12.3-2.1
Cocaine response before conditioning0.40.51.90.70.31.40.3-0.10.10.20.2-0.40.20.2-0.30.40.30.71.30.80.80.61.1-1.3
Saline control response0.30.50.80.20.5-0.40.5-0.40.60.70.70.6-0.7-0.70.7-0.7-0.8-0.8-0.7-0.8-0.8-0.9-0.80.9
Bone: connectivity density0.10.20.50.60.40.40.3-0.60.40.40.30.4-0.6-0.60.5-0.5-0.7-0.30.2-0.3-0.4-0.6-0.20.5
Bone: cortical apparent density2.94.510.6-3.3-2.1-2.8-2.12.7-2.8-2.8-2.8-2.22.32.3-2.12.02.11.60.11.51.21.50.4-0.5
Bone: cortical area0.91.52.4-0.7-1.50.2-1.51.1-1.0-1.0-1.0-1.21.21.3-1.21.31.41.30.91.21.41.51.2-1.3
Bone: cortical porosity1.51.63.01.51.60.91.7-1.41.41.41.31.2-1.4-1.51.2-1.3-1.5-1.1-0.1-1.1-1.1-1.3-0.70.8
Bone: cortical porosity1.21.32.91.71.51.51.6-1.41.31.41.31.0-1.2-1.20.9-1.0-1.2-0.70.5-0.7-0.6-0.9-0.10.1
Bone: cortical thickness0.91.53.9-1.8-2.0-1.6-2.01.5-1.4-1.4-1.5-1.11.21.3-1.01.01.20.8-0.30.70.70.90.1-0.2
Bone: cortical thickness0.30.40.6-0.3-0.50.2-0.50.5-0.5-0.6-0.6-0.70.70.7-0.70.70.70.80.60.80.70.80.7-0.7
Bone: cortical tissue density2.84.410.1-3.2-2.0-2.7-2.12.7-2.7-2.8-2.8-2.22.32.3-2.11.92.11.60.21.51.21.50.4-0.5
Condit. Reinf. active minus inactive responses2.52.86.42.52.22.32.2-2.12.12.22.11.8-1.7-1.61.5-1.4-1.2-1.1-0.9-1.1-0.7-0.6-0.2-0.2
Condit. Reinf. active-inactive response ratio1.61.73.71.91.71.71.8-1.51.71.81.71.4-1.4-1.21.1-1.1-1.0-1.0-0.8-0.9-0.6-0.5-0.2-0.2
Condit. Reinf. active responses1.11.45.52.11.62.41.6-1.51.51.51.51.1-1.1-0.90.9-0.7-0.6-0.5-0.2-0.5-0.00.00.5-0.8
Condit. Reinf. inactive responses0.30.40.8-0.1-0.50.5-0.60.3-0.4-0.5-0.5-0.50.60.6-0.40.70.80.70.50.60.80.90.8-0.8
Incentive salience index mean2.33.05.82.42.21.92.2-2.12.22.22.21.9-1.9-1.81.7-1.6-1.5-1.4-0.9-1.4-1.1-1.1-0.60.3
Condit. Reinf. lever presses1.42.12.71.41.50.61.5-1.61.61.61.61.6-1.6-1.61.6-1.5-1.5-1.5-1.3-1.5-1.4-1.3-1.21.2
Condit. Reinf. active minus inactive responses0.81.25.42.01.22.31.3-1.41.41.41.40.8-0.9-0.80.6-0.5-0.5-0.10.4-0.10.10.00.6-0.8
Condit. Reinf. active-inactive response ratio1.11.74.12.01.51.81.6-1.71.71.71.71.3-1.4-1.41.2-1.2-1.2-0.8-0.2-0.8-0.7-0.8-0.20.1
Condit. Reinf. active responses0.20.32.00.9-0.01.40.0-0.40.50.40.40.0-0.00.1-0.10.20.20.50.60.50.60.60.9-0.9
Condit. Reinf. inactive responses0.71.11.5-0.5-1.20.3-1.20.9-0.8-0.8-0.8-1.11.11.1-1.11.11.11.21.11.21.21.21.2-1.1
Condit. Reinf. lever presses0.00.10.20.3-0.50.4-0.4-0.00.20.20.2-0.1-0.1-0.1-0.20.0-0.10.10.40.10.10.00.2-0.3
Condit. Reinf. lever reinforcers received0.30.41.90.7-0.31.4-0.2-0.10.20.20.2-0.30.20.3-0.40.50.50.70.80.70.90.91.1-1.1
Conditioned reinforcement - actives0.00.10.2-0.4-0.1-0.4-0.20.3-0.4-0.3-0.3-0.20.30.3-0.20.30.30.1-0.00.10.20.20.0-0.1
Conditioned reinforcement - inactives0.10.10.30.00.10.40.20.2-0.2-0.4-0.4-0.20.30.3-0.30.30.40.50.40.50.50.50.5-0.6
Conditioned locomotion2.84.15.7-2.0-1.6-0.8-1.82.2-2.4-2.3-2.3-2.42.32.2-2.12.22.12.12.22.02.01.81.7-1.6
Patch foraging indifference point 0 sec0.92.58.9-2.4-3.0-2.4-2.62.2-1.9-1.7-1.7-1.61.41.2-1.61.00.80.80.80.60.20.1-0.20.0
Patch foraging indifference point AUC0.61.34.3-0.6-1.20.1-0.91.3-1.0-0.9-0.8-1.51.11.0-1.61.20.81.12.11.21.10.81.3-1.3
Delay disc. indifference point, 0s delay0.00.00.2-0.0-0.3-0.0-0.20.2-0.1-0.2-0.2-0.10.0-0.0-0.30.0-0.10.10.40.2-0.1-0.20.00.1
Delay disc. indifference point, 16s delay0.40.61.10.90.80.60.9-0.91.01.01.10.9-0.8-0.70.9-0.7-0.6-0.8-0.9-0.8-0.5-0.4-0.40.5
Delay disc. indifference point, 2s delay0.10.10.4-0.1-0.30.1-0.20.1-0.3-0.3-0.3-0.40.20.2-0.10.20.10.50.60.60.20.10.3-0.2
Delay disc. indifference point, 24s delay0.40.62.50.20.6-0.50.7-0.50.60.60.70.9-0.7-0.60.7-0.8-0.5-0.9-1.6-1.0-0.8-0.6-1.01.0
Delay disc. indifference point, 4s delay0.30.30.8-0.7-0.9-0.6-0.60.7-0.6-0.7-0.7-0.40.50.4-0.60.40.40.50.10.50.20.20.00.2
Delay disc. indifference point, 8s delay0.10.10.40.60.40.70.6-0.20.50.40.50.3-0.3-0.20.1-0.1-0.00.0-0.30.10.10.20.1-0.2
Indifference point function ln k0.41.14.1-0.30.2-1.30.3-0.60.40.30.41.0-0.8-0.81.1-1.0-0.8-1.1-2.0-1.2-1.3-1.0-1.62.0
Indifference point function log k0.41.14.1-0.30.2-1.30.3-0.60.40.30.41.0-0.8-0.81.1-1.0-0.8-1.1-2.0-1.2-1.3-1.0-1.62.0
Patch foraging total patch changes 0 sec0.92.58.9-2.4-3.0-2.4-2.62.2-1.9-1.8-1.7-1.71.41.1-1.71.00.70.81.00.60.30.1-0.10.0
Patch foraging total patch changes 12 sec0.91.23.3-0.9-1.8-0.4-1.51.4-1.0-0.9-0.8-1.31.00.9-1.51.00.60.91.60.80.70.40.8-1.0
Patch foraging total patch changes 18 sec0.51.23.7-1.5-1.9-1.4-1.71.5-1.3-1.1-1.1-1.41.10.9-1.30.90.50.71.20.70.30.10.2-0.3
Patch foraging total patch changes 24 sec0.31.03.6-1.1-1.9-0.8-1.61.2-1.1-1.0-1.0-1.30.90.7-1.10.80.50.71.40.80.40.20.4-0.5
Patch foraging total patch changes 6 sec1.72.98.3-2.3-2.9-2.1-2.62.3-2.0-1.9-1.9-1.91.61.4-1.91.30.91.11.40.90.60.30.3-0.3
Patch foraging time to switch 0 sec0.20.91.71.21.30.91.2-1.21.11.21.11.3-1.0-0.91.0-0.9-0.7-0.8-0.8-0.8-0.5-0.5-0.40.1
Patch foraging water rate 0 sec0.20.61.4-1.2-1.0-1.0-1.10.9-1.0-1.0-1.0-1.00.80.8-0.60.70.70.60.30.60.40.50.20.3
Patch foraging water rate 12 sec0.10.31.4-0.30.1-0.90.2-0.20.10.00.10.4-0.3-0.30.7-0.4-0.3-0.5-1.0-0.6-0.7-0.5-0.91.2
Patch foraging water rate 18 sec0.51.13.00.31.0-0.51.0-0.90.80.80.91.1-1.0-0.91.3-1.1-0.8-1.1-1.7-1.2-1.1-0.9-1.31.5
Patch foraging water rate 24 sec0.00.10.2-0.0-0.10.2-0.3-0.2-0.1-0.0-0.1-0.10.20.30.30.20.40.2-0.30.10.30.50.20.2
Patch foraging water rate 6 sec0.40.73.0-0.7-0.0-1.5-0.1-0.1-0.1-0.1-0.10.4-0.4-0.30.8-0.6-0.5-0.8-1.4-0.7-1.0-0.8-1.31.7
Seeking ratio, delayed vs. immediate footshock0.50.73.71.51.01.90.7-0.91.01.11.10.4-0.5-0.50.2-0.3-0.4-0.10.90.10.20.10.7-0.7
Distance traveled before self-admin0.71.56.62.21.62.61.4-1.51.41.31.40.8-1.0-1.00.6-0.7-0.9-0.21.2-0.20.0-0.30.7-0.6
Distance traveled after self-admin0.30.62.21.31.21.51.1-0.80.80.80.80.6-0.6-0.60.4-0.4-0.4-0.20.40.10.0-0.10.4-0.6
Extensor digitorum longus weight6.827.135.4-5.8-5.8-3.1-5.85.9-6.0-5.9-5.9-5.75.95.8-5.45.55.75.13.14.94.74.93.5-3.0
Bone: elastic displacement1.92.43.41.01.4-0.21.5-1.31.41.41.41.8-1.7-1.71.4-1.8-1.7-1.8-1.7-1.8-1.8-1.8-1.71.6
Bone: elastic work0.60.82.11.51.41.41.4-1.01.11.11.10.8-0.9-0.90.6-0.7-0.8-0.50.1-0.5-0.3-0.40.1-0.1
Bone: endosteal estimation0.71.810.42.00.53.20.5-0.60.80.80.9-0.30.00.0-0.40.50.30.92.41.01.31.02.1-2.1
Bone: endosteal perimeter0.20.63.81.20.22.00.2-0.40.50.60.6-0.00.00.1-0.10.30.30.51.00.50.90.81.2-1.3
Epididymis fat weight0.42.05.10.2-0.31.7-0.10.7-0.7-0.6-0.6-1.31.21.4-1.31.61.61.71.51.82.02.12.2-2.3
Delta time in closed arm before/after self-admin0.40.40.8-0.8-0.9-0.6-0.60.7-0.6-0.8-0.8-0.70.60.6-0.50.50.50.60.30.70.30.30.2-0.3
Delta time in open arm before/after self-admin1.41.64.42.12.12.11.8-1.51.51.41.51.1-1.2-1.20.8-1.0-1.1-0.70.6-0.7-0.4-0.70.2-0.1
Diff in mean of infusions in LGA sessions0.50.81.61.21.11.01.1-1.21.11.21.11.0-1.0-0.91.0-0.9-0.8-0.8-0.5-0.9-0.6-0.5-0.30.2
Delay discount exponential model param0.00.00.3-0.0-0.00.1-0.30.0-0.1-0.1-0.1-0.20.20.1-0.10.20.10.10.50.10.20.10.3-0.4
Extinction: sum of active levers before priming0.60.91.91.20.70.80.7-1.11.21.41.31.2-1.1-1.00.9-0.9-0.8-1.0-0.8-0.8-0.7-0.6-0.50.2
Active lever presses in extinction session 61.11.12.91.21.70.81.7-1.11.11.31.21.0-1.1-1.00.9-1.0-1.0-0.8-0.6-0.9-0.8-0.7-0.50.6
Bone: final force1.01.63.80.2-0.71.5-0.80.5-0.6-0.6-0.6-1.11.01.1-1.11.31.21.51.91.51.71.61.9-1.7
Bone: final moment0.81.32.8-0.0-1.01.1-1.00.6-0.7-0.6-0.7-1.11.11.1-1.01.31.21.41.61.31.51.41.7-1.4
Food consumed during 24 hour testing period0.30.72.70.30.21.10.20.3-0.3-0.3-0.3-0.80.60.6-0.70.80.60.91.71.01.00.81.3-1.4
Glucose1.11.83.60.10.5-1.20.5-0.90.90.90.91.3-1.3-1.31.5-1.5-1.4-1.6-1.8-1.7-1.8-1.7-1.91.8
Heart weight0.00.10.50.40.30.70.3-0.10.20.40.4-0.0-0.0-0.0-0.10.10.0-0.10.30.10.20.20.4-0.2
Delay discount hyperbolic model param0.00.00.20.10.10.2-0.1-0.1-0.1-0.0-0.1-0.20.10.10.00.10.10.10.50.00.20.10.3-0.4
Intermittent access intake day 1-15 change0.00.21.0-0.7-0.9-0.9-0.21.0-0.3-0.2-0.2-0.30.30.3-0.60.20.3-0.1-0.7-0.1-0.10.1-0.3-0.0
Intermittent access intake escalation0.10.41.6-1.0-1.2-1.3-0.51.2-0.4-0.2-0.2-0.20.30.3-0.70.10.2-0.3-0.9-0.3-0.3-0.1-0.60.3
Intermittent access intake escalation 20.20.41.4-0.1-0.4-0.80.30.20.30.40.50.5-0.5-0.50.1-0.6-0.5-0.9-1.2-0.9-0.9-0.7-1.00.7
Intermitt. access day 1 inactive lever presses0.10.95.6-1.6-1.3-2.4-1.00.9-0.5-0.5-0.5-0.00.20.1-0.1-0.2-0.1-0.6-1.2-0.7-0.8-0.7-1.31.0
Intermitt. access day 15 inactive lever presses0.00.10.4-0.5-0.1-0.6-0.2-0.0-0.3-0.4-0.50.10.20.10.2-0.00.2-0.1-0.5-0.3-0.0-0.0-0.30.3
Intermitt. access escalation Index0.10.52.8-0.20.0-0.70.3-0.20.40.50.50.7-0.4-0.30.7-0.6-0.3-0.7-1.7-0.8-0.7-0.4-1.01.0
Intermittent access day 1 total infusions0.20.71.30.70.50.10.5-1.00.80.70.71.2-1.0-1.01.1-1.0-0.9-1.0-1.0-0.9-0.9-0.9-0.90.7
Intermittent access day 15 total infusions0.30.63.1-0.8-0.9-1.6-0.40.4-0.10.00.00.5-0.3-0.30.2-0.5-0.3-0.9-1.8-0.8-0.9-0.6-1.30.9
Intermittent access terminal intake (last 3 days)0.40.73.3-1.0-1.0-1.8-0.50.4-0.3-0.2-0.20.3-0.1-0.20.3-0.4-0.2-0.8-1.6-0.7-0.9-0.7-1.30.9
Intermittent access total infusions0.30.41.3-0.1-0.3-0.7-0.1-0.30.10.10.10.7-0.5-0.50.6-0.6-0.5-0.8-1.1-0.6-0.8-0.7-1.00.8
Intermittent access day 1 locomotion0.00.00.1-0.10.3-0.00.1-0.2-0.3-0.2-0.30.00.10.10.20.10.10.10.00.20.10.10.0-0.0
Intermittent access day 15 total locomotion0.31.01.7-0.9-0.9-0.4-0.91.0-1.3-1.3-1.3-1.01.11.1-1.11.11.11.10.71.11.01.00.8-0.7
Intermittent access total locomotion0.30.31.0-0.9-0.8-1.0-0.80.5-0.9-0.8-0.8-0.30.50.5-0.30.30.40.2-0.10.30.10.1-0.20.3
Intermittent access standard deviation0.10.41.4-0.7-1.2-0.6-0.61.1-0.8-0.7-0.7-0.70.50.5-0.80.50.40.40.10.40.20.30.1-0.2
Left kidney weight0.00.30.70.50.50.40.6-0.40.60.80.80.6-0.5-0.40.4-0.4-0.4-0.6-0.5-0.6-0.3-0.3-0.30.2
Right kidney weight0.10.81.4-0.8-1.0-0.2-0.91.2-0.8-0.5-0.5-1.01.01.0-1.11.01.10.70.70.71.01.00.8-0.6
Cocaine induced anxiety0.30.82.1-1.5-0.8-1.3-0.91.2-1.2-1.3-1.3-0.91.01.0-0.80.80.90.7-0.00.60.50.60.10.0
Post-drug Anxiety1.31.52.5-1.5-1.3-1.0-1.41.5-1.5-1.6-1.6-1.21.41.4-1.11.21.31.20.41.01.01.10.6-0.5
Baseline Anxiety0.20.31.61.10.41.30.4-0.60.90.80.80.4-0.5-0.50.3-0.3-0.3-0.20.2-0.10.0-0.00.3-0.5
Tail length1.36.917.34.23.94.03.7-3.43.33.33.32.7-2.5-2.42.3-2.0-1.9-1.6-0.5-1.6-0.8-1.00.1-0.2
Length with tail1.35.827.64.33.75.33.5-2.82.72.82.81.7-1.6-1.41.3-0.9-0.9-0.31.0-0.30.60.41.7-1.9
Length without tail0.52.510.51.60.83.20.9-0.10.10.30.3-0.80.60.7-1.01.10.91.52.51.51.91.72.7-2.7
Times rat made contact with spout2.12.43.70.71.1-0.61.0-1.31.31.31.31.7-1.6-1.71.7-1.8-1.8-1.8-1.7-1.9-1.9-1.9-1.91.7
Lifetime Intake0.20.20.8-0.6-0.8-0.9-0.70.2-0.5-0.5-0.50.10.10.00.0-0.1-0.0-0.2-0.6-0.1-0.3-0.2-0.60.3
Liver weight, left0.30.62.40.70.21.50.20.10.10.10.1-0.50.40.4-0.40.70.60.81.30.91.10.91.4-1.1
Liver weight, right0.10.21.20.70.41.10.5-0.30.40.50.5-0.1-0.0-0.00.10.10.10.20.60.20.40.30.7-0.6
Locomotor activity0.00.00.2-0.2-0.5-0.1-0.40.2-0.1-0.2-0.1-0.20.20.2-0.10.10.10.30.10.20.10.10.1-0.1
Locomotor testing distance0.20.50.90.50.3-0.10.4-0.60.80.70.80.7-0.8-0.90.7-0.8-0.9-0.7-0.5-0.8-0.9-1.0-0.80.7
Locomotor testing rearing0.31.13.3-0.10.1-1.10.3-0.60.70.80.81.1-0.9-0.91.0-1.1-1.0-1.3-1.8-1.4-1.4-1.2-1.61.3
Locomotion in novel chamber3.64.87.4-1.8-2.1-0.4-2.02.5-2.2-2.2-2.1-2.62.42.3-2.72.42.22.22.42.32.22.12.0-1.9
Locomotion in novel chamber post-restriction1.54.56.4-1.8-2.2-0.5-2.52.0-2.4-2.4-2.4-2.32.32.2-2.22.22.22.32.12.22.12.01.8-1.3
Fecal boli incidents, locomotor time 10.10.20.80.20.9-0.10.8-0.60.30.30.30.3-0.4-0.50.6-0.5-0.5-0.4-0.1-0.4-0.5-0.6-0.40.2
Change in fecal boli incidents, locomotor task0.10.10.7-0.2-0.3-0.5-0.1-0.0-0.00.10.10.3-0.2-0.20.3-0.3-0.2-0.3-0.7-0.5-0.3-0.3-0.50.9
Time >=10cm from walls, locomotor time 11.11.42.5-0.6-1.30.3-1.01.2-0.9-0.8-0.8-1.31.21.2-1.61.31.31.31.21.11.31.31.3-1.6
Bouts of movement, locomotor time 10.30.41.4-1.1-1.0-1.2-1.00.6-0.9-0.9-1.0-0.50.60.6-0.20.40.50.4-0.20.30.10.2-0.20.2
Total resting periods, locomotor time 10.80.92.2-1.5-1.3-1.3-1.31.0-1.3-1.3-1.3-0.91.01.0-0.60.80.90.70.10.70.50.60.1-0.1
Rest time, locomotor task time 10.20.31.0-0.5-0.2-1.0-0.1-0.20.00.10.10.3-0.2-0.30.7-0.4-0.4-0.8-0.8-0.8-0.7-0.7-0.90.9
Distance moved, locomotor task time 10.10.20.60.60.30.50.3-0.30.60.50.60.6-0.4-0.30.1-0.3-0.2-0.3-0.7-0.3-0.2-0.0-0.20.2
Vertical activity count, locomotor time 10.00.00.20.0-0.20.2-0.10.3-0.00.0-0.0-0.10.10.1-0.50.10.20.1-0.00.20.20.20.2-0.1
Time >=10cm from walls, locomotor time 20.51.42.51.41.20.91.4-1.11.41.61.61.3-1.3-1.30.9-1.2-1.2-1.1-0.7-1.2-0.9-1.0-0.60.7
Bouts of movement, locomotor time 20.51.84.5-2.1-1.9-2.0-1.71.6-1.7-1.6-1.6-1.11.41.4-1.11.11.30.9-0.40.80.70.90.00.2
Total resting periods, locomotor time 20.41.74.4-2.1-1.9-2.0-1.71.6-1.7-1.5-1.6-1.11.31.3-1.11.01.20.8-0.30.70.60.7-0.10.3
Rest time, locomotor task time 20.20.32.0-0.9-0.5-1.4-0.50.4-0.5-0.4-0.5-0.20.1-0.00.1-0.1-0.3-0.4-0.2-0.4-0.5-0.7-0.70.8
Distance moved, locomotor task time 20.10.21.00.80.31.00.2-0.30.60.60.60.4-0.3-0.10.0-0.10.10.1-0.30.00.20.40.3-0.4
Vertical activity count, locomotor time 20.00.10.7-0.0-0.0-0.20.0-0.00.20.30.30.3-0.2-0.10.1-0.2-0.0-0.2-0.8-0.4-0.2-0.0-0.40.4
Light reinforcement 11.56.711.1-3.3-3.1-2.4-2.93.2-3.2-3.2-3.0-3.02.92.8-2.82.62.52.11.62.11.91.91.2-1.3
Light reinforcement 20.41.02.1-1.3-0.7-0.9-0.71.2-1.3-1.5-1.4-1.21.11.0-1.10.90.81.01.00.80.70.50.5-0.3
Bone: marrow area0.71.79.61.90.43.10.4-0.60.70.70.8-0.30.10.1-0.50.60.31.02.41.01.31.02.1-2.0
Bone: maximum diameter0.10.31.2-0.3-1.00.1-1.10.4-0.3-0.3-0.3-0.40.50.6-0.40.60.70.50.10.40.60.70.5-0.5
Bone: maximum force1.22.47.00.6-0.52.2-0.60.5-0.5-0.4-0.5-1.31.11.2-1.31.51.31.82.71.82.01.82.5-2.2
Bone: maximum moment1.01.95.60.3-0.81.7-0.80.6-0.6-0.6-0.6-1.31.11.1-1.21.41.21.72.41.71.81.62.2-1.8
Mean time between licks in bursts0.63.56.3-2.0-2.5-1.1-2.42.3-2.1-2.1-2.0-2.22.01.9-2.01.91.81.61.61.61.51.41.2-0.9
Mean num. licks in bursts0.10.30.6-0.2-0.40.2-0.40.5-0.4-0.4-0.4-0.50.50.4-0.60.50.40.60.80.60.50.50.6-0.6
Cd content in liver2.32.64.01.91.81.21.8-2.01.91.91.91.9-1.8-1.71.7-1.6-1.4-1.5-1.5-1.4-1.2-1.1-1.00.7
Co content in liver2.52.94.71.21.50.11.5-1.71.71.71.72.0-1.8-1.71.9-1.8-1.6-2.0-2.2-2.0-1.7-1.6-1.71.6
Cu content in liver1.62.02.91.61.70.91.7-1.71.61.61.61.6-1.5-1.51.4-1.4-1.3-1.3-1.1-1.3-1.2-1.1-0.90.8
Fe content in liver3.54.35.52.02.20.82.2-2.22.32.32.32.3-2.3-2.32.1-2.3-2.3-2.2-1.4-2.1-2.1-2.1-1.71.6
K content in liver2.22.13.6-1.5-1.7-0.8-1.71.7-1.5-1.6-1.6-1.81.51.4-1.81.41.11.31.91.31.10.81.0-1.1
Mg content in liver0.30.30.8-0.7-0.9-0.6-0.90.6-0.5-0.6-0.6-0.60.50.3-0.70.30.10.30.80.30.1-0.10.1-0.2
Mn content in liver0.20.21.0-0.6-0.6-1.0-0.60.2-0.3-0.5-0.50.0-0.1-0.10.0-0.2-0.3-0.1-0.2-0.1-0.5-0.6-0.70.8
Na content in liver0.00.00.20.20.00.10.0-0.10.20.20.2-0.0-0.2-0.3-0.0-0.2-0.4-0.20.5-0.2-0.2-0.4-0.10.1
Rb content in liver3.94.56.2-2.1-2.3-0.9-2.22.4-2.2-2.2-2.3-2.22.42.4-2.42.32.52.01.12.02.12.31.6-1.8
Se content in liver0.10.10.3-0.5-0.3-0.4-0.20.5-0.3-0.4-0.3-0.50.40.4-0.50.40.30.30.30.20.20.20.2-0.1
Sr content in liver0.10.10.3-0.4-0.3-0.6-0.30.2-0.2-0.2-0.20.00.00.0-0.1-0.10.0-0.1-0.4-0.2-0.2-0.1-0.30.2
Zn content in liver0.00.00.2-0.1-0.4-0.2-0.40.1-0.1-0.0-0.0-0.10.10.1-0.10.10.10.0-0.0-0.00.00.0-0.0-0.1
Bone: minimum diameter0.91.73.70.1-1.21.3-1.20.7-0.8-0.8-0.8-1.21.11.1-1.21.41.21.71.91.71.61.51.9-1.7
Time in familiar zone, hab. session 10.30.31.4-0.30.2-0.90.2-0.10.20.10.20.5-0.3-0.30.4-0.5-0.4-0.6-1.2-0.7-0.7-0.5-0.91.0
Time in novel zone, hab. session 12.02.34.62.11.91.81.9-1.91.91.91.91.5-1.6-1.61.4-1.4-1.5-1.1-0.2-1.1-0.9-1.1-0.40.3
Total zone transitions, hab. session 11.01.42.7-0.2-0.20.9-0.30.9-1.0-0.9-1.0-1.21.11.2-1.21.31.21.51.61.41.51.41.6-1.6
Total locomotion distance, hab. session 12.23.17.90.1-0.71.8-0.71.0-1.1-1.1-1.1-1.81.61.6-1.61.91.72.22.82.22.32.12.7-2.3
Locomotion velocity, hab. session 12.94.27.9-0.7-1.51.0-1.51.6-1.7-1.7-1.7-2.32.02.0-2.02.32.12.52.82.52.52.32.6-2.3
Time in familiar zone, hab. session 20.20.20.40.20.5-0.20.5-0.30.40.40.40.6-0.5-0.50.5-0.6-0.5-0.6-0.6-0.6-0.6-0.5-0.60.4
Time in novel zone, hab. session 20.20.20.40.20.0-0.20.0-0.50.40.40.40.5-0.4-0.40.6-0.5-0.4-0.5-0.6-0.5-0.5-0.4-0.50.4
Total zone transitions, hab. session 20.00.10.3-0.00.1-0.20.1-0.20.10.10.10.3-0.2-0.20.4-0.2-0.1-0.3-0.5-0.3-0.2-0.2-0.30.2
Total locomotion distance, hab. session 20.30.41.00.3-0.40.9-0.50.1-0.1-0.1-0.1-0.40.40.5-0.30.60.70.70.60.70.90.91.0-1.0
Locomotion velocity, hab. session 20.50.71.50.1-0.60.9-0.70.3-0.4-0.4-0.4-0.70.70.8-0.60.90.91.00.91.01.11.21.2-1.2
Novel to familiar place preference ratio0.81.02.11.41.21.21.2-1.21.41.41.41.0-1.1-1.10.8-0.9-1.0-0.8-0.2-0.7-0.6-0.7-0.30.1
Novelty place preference1.01.22.21.31.10.81.1-1.31.51.51.51.2-1.2-1.21.0-1.1-1.2-1.1-0.6-1.0-0.9-1.0-0.60.5
Time in novel zone, NPP test1.31.62.71.51.20.91.2-1.41.61.61.61.4-1.4-1.41.2-1.3-1.3-1.2-0.8-1.2-1.0-1.1-0.70.6
Total zone transitions, NPP test0.30.40.7-0.8-0.5-0.6-0.60.7-0.8-0.8-0.8-0.40.70.7-0.40.60.80.5-0.40.50.50.70.2-0.3
Total locomotion distance, NPP test0.50.71.7-0.1-0.60.7-0.60.4-0.7-0.7-0.7-0.90.80.8-0.70.90.81.11.31.11.00.91.2-1.0
Locomotion velocity, NPP test0.81.12.1-0.5-0.90.3-1.00.8-1.0-1.1-1.1-1.21.11.1-1.01.21.01.31.51.31.21.11.2-1.0
Intraocular pressure0.10.20.9-0.4-0.4-0.8-0.40.0-0.1-0.1-0.10.3-0.2-0.10.3-0.3-0.1-0.3-1.0-0.3-0.5-0.3-0.70.6
Delta distance traveled before/after self-admin0.10.10.6-0.6-0.2-0.7-0.20.4-0.5-0.3-0.4-0.10.30.4-0.00.20.40.1-0.80.10.10.3-0.20.1
Delta ambulatory time before/after self-admin0.20.30.8-0.9-0.7-0.8-0.60.7-0.7-0.6-0.6-0.40.50.6-0.40.50.60.3-0.60.50.30.5-0.1-0.1
Parametrial fat weight0.20.41.8-1.0-0.8-1.4-0.80.2-0.5-0.4-0.5-0.00.20.20.3-0.00.1-0.3-0.8-0.5-0.3-0.2-0.71.2
Pavlov. Cond. lever latency2.93.74.7-2.1-2.0-1.1-2.02.2-2.2-2.2-2.2-2.12.22.1-2.12.12.11.91.32.01.81.81.4-1.3
Pavlov. Cond. magazine entry latency2.32.95.92.32.41.92.4-2.12.12.02.11.7-1.8-1.81.7-1.5-1.6-1.3-0.5-1.2-1.1-1.1-0.50.3
Pavlov. Cond. change in total contacts1.92.13.41.81.41.21.5-1.71.81.81.91.7-1.6-1.51.6-1.4-1.3-1.3-1.1-1.4-1.1-1.0-0.70.6
Pavlov. Cond. index score3.54.45.92.32.31.32.4-2.42.42.42.42.3-2.4-2.32.3-2.2-2.2-2.1-1.4-2.0-1.8-1.9-1.41.3
Pavlov. Cond. latency score3.34.25.92.32.41.42.4-2.42.42.42.42.2-2.3-2.32.2-2.1-2.1-1.9-1.2-1.9-1.7-1.8-1.21.1
Pavlov. Cond. lever contacts3.03.74.61.91.80.91.9-2.12.12.12.12.2-2.1-2.12.1-2.1-2.0-2.0-1.4-2.0-1.8-1.9-1.51.4
Pavlov. Cond. magazine entry number3.64.57.6-2.7-2.8-1.9-2.72.5-2.6-2.5-2.6-2.32.32.2-2.22.02.01.81.11.81.51.60.9-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.3-0.6-0.1-0.60.3-0.3-0.3-0.3-0.20.40.4-0.30.40.50.3-0.20.30.40.50.2-0.2
Pavlov. Cond. lever-magazine prob. diff.2.93.64.92.22.11.32.2-2.22.22.22.22.1-2.1-2.12.1-2.0-1.9-1.8-1.2-1.8-1.6-1.7-1.21.0
Pavlov. Cond. response bias3.64.46.22.42.51.52.5-2.42.52.52.52.3-2.3-2.32.2-2.1-2.1-2.0-1.3-1.9-1.7-1.8-1.21.1
Pavlov. Cond. lever latency0.10.10.5-0.50.1-0.7-0.00.2-0.3-0.3-0.30.00.20.20.10.00.2-0.1-0.7-0.1-0.10.0-0.40.5
Pavlov. Cond. magazine entry latency0.10.10.60.70.00.80.1-0.40.40.40.40.1-0.3-0.30.1-0.2-0.30.00.40.0-0.0-0.10.2-0.3
Pavlov. Cond. change in total contacts0.20.51.71.20.71.30.8-0.90.91.01.00.5-0.7-0.70.4-0.5-0.7-0.30.6-0.2-0.2-0.40.3-0.4
Pavlov. Cond. index score0.10.21.30.8-0.01.20.1-0.30.40.50.5-0.1-0.2-0.2-0.20.0-0.20.20.90.20.30.10.6-0.7
Pavlov. Cond. latency score0.20.31.40.7-0.11.20.0-0.10.20.30.3-0.30.00.0-0.40.20.00.41.20.50.50.30.8-0.9
Pavlov. Cond. lever contacts0.20.30.90.90.20.90.3-0.60.70.70.70.3-0.5-0.60.3-0.4-0.6-0.20.5-0.3-0.2-0.40.1-0.2
Pavlov. Cond. magazine entry number0.20.20.8-0.9-0.4-0.9-0.40.6-0.6-0.6-0.6-0.30.50.5-0.20.40.60.2-0.50.20.20.4-0.10.2
Pavlov. Cond. intertrial magazine entries0.10.31.3-1.0-0.7-1.2-0.80.5-0.7-0.6-0.7-0.30.50.5-0.20.30.40.1-0.60.00.00.2-0.30.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.6-0.20.9-0.1-0.10.20.30.3-0.2-0.0-0.0-0.30.1-0.10.30.90.30.30.20.6-0.7
Pavlov. Cond. response bias0.30.42.11.20.31.40.3-0.70.70.70.70.2-0.5-0.50.1-0.3-0.50.11.00.10.1-0.20.5-0.7
Time in closed arm before self-admin0.61.12.81.71.51.71.3-1.21.21.51.20.8-1.0-1.00.7-0.8-1.0-0.70.5-0.8-0.4-0.60.20.2
Time in closed arm after self-admin0.10.10.50.50.30.70.4-0.10.20.30.2-0.0-0.1-0.1-0.1-0.0-0.1-0.00.3-0.10.10.10.3-0.3
Time in open arm before self-admin1.01.22.8-1.7-1.5-1.5-1.21.4-1.2-1.2-1.2-0.91.11.3-0.91.01.30.8-0.90.90.61.00.0-0.5
Time in open arm after self-admin0.80.93.81.71.62.01.5-1.11.11.01.10.6-0.7-0.70.4-0.4-0.5-0.10.7-0.10.1-0.10.6-0.7
Bone: periosteal estimation0.61.45.21.1-0.52.3-0.50.00.10.10.2-0.70.50.6-0.80.90.81.22.01.21.51.32.0-2.0
Bone: periosteal perimeter0.10.21.40.8-0.21.2-0.2-0.30.50.50.50.2-0.10.00.10.10.20.20.30.20.50.50.7-0.8
Bone: post-yield work0.40.62.40.70.11.60.1-0.10.10.00.1-0.50.40.4-0.40.60.50.91.41.01.00.91.4-1.1
Progressive ratio test 1 active lever presses0.20.31.3-0.9-1.1-1.1-0.70.7-0.6-0.5-0.5-0.10.30.3-0.30.20.2-0.1-0.8-0.1-0.20.0-0.50.2
Progressive ratio test 1 breakpoint0.10.20.9-0.7-0.9-0.8-0.60.5-0.5-0.4-0.4-0.10.20.2-0.30.10.2-0.1-0.6-0.0-0.10.1-0.40.1
Progressive ratio test 1 inactive lever presses0.41.02.8-1.6-1.4-1.7-1.01.6-1.2-1.1-1.1-0.70.90.9-1.00.70.80.4-0.40.20.30.4-0.2-0.1
Progressive ratio test 2 active lever presses0.10.10.9-0.5-0.8-0.7-0.50.3-0.1-0.2-0.10.10.00.1-0.1-0.00.1-0.3-1.0-0.1-0.20.0-0.50.2
Progressive ratio test 2 breakpoint0.20.21.4-0.5-0.9-0.9-0.50.3-0.1-0.1-0.10.3-0.00.0-0.0-0.10.0-0.4-1.2-0.3-0.4-0.1-0.70.4
Progressive ratio test 2 inactive lever presses0.10.20.8-0.5-0.6-0.7-0.20.7-0.2-0.3-0.30.20.10.1-0.5-0.00.2-0.2-0.9-0.2-0.10.0-0.4-0.0
Incentive Sensitization - Responses0.10.20.90.4-0.10.2-0.0-0.40.60.60.60.7-0.5-0.40.4-0.5-0.3-0.6-0.9-0.5-0.4-0.2-0.40.3
Incentive Sensitization - Breakpoint0.10.21.00.3-0.3-0.0-0.2-0.30.50.50.50.6-0.4-0.30.3-0.4-0.2-0.6-1.0-0.5-0.4-0.2-0.50.4
Sum of active levers in priming session hrs 5-61.51.43.71.91.61.91.8-1.51.51.51.51.2-1.2-1.11.1-0.9-0.8-0.7-0.4-0.5-0.4-0.30.0-0.0
Progressive ratio0.51.42.4-0.9-1.3-0.1-1.41.1-1.1-1.2-1.1-1.01.31.4-1.21.31.51.20.41.21.31.51.1-1.1
Food seeking constrained by brief footshock1.01.32.0-0.6-1.10.3-0.71.1-1.0-0.9-0.9-1.21.21.2-1.41.31.21.21.01.41.31.41.3-1.4
Seeking ratio, punishment vs. effort0.10.11.00.1-0.00.40.20.3-0.2-0.1-0.1-0.50.20.1-0.40.30.00.41.00.40.30.10.5-0.6
Retroperitoneal fat weight0.41.62.3-1.2-1.4-0.5-1.31.2-1.4-1.4-1.4-1.31.41.5-1.11.41.51.30.61.11.31.41.0-0.8
Reaction time number correct0.31.02.3-1.5-1.3-1.3-1.21.2-1.2-1.1-1.1-1.11.11.1-0.71.01.00.70.10.70.60.70.20.1
Reaction time mean minus median0.31.63.92.01.71.81.7-1.81.51.31.41.2-1.4-1.41.1-1.1-1.4-0.60.4-0.4-0.7-0.9-0.10.1
Reaction time mean minus median AUC0.31.74.01.82.01.51.9-1.91.51.31.41.2-1.4-1.41.5-1.2-1.3-0.80.0-0.6-0.8-1.0-0.30.5
Reaction time num false alarms2.33.96.8-2.6-2.3-2.0-2.52.2-2.5-2.5-2.5-1.92.12.2-1.91.92.11.90.31.61.41.70.7-0.9
Reaction time num false alarms AUC2.25.08.2-2.8-2.5-1.9-2.72.5-2.8-2.9-2.8-2.32.42.4-2.22.22.32.20.91.91.71.81.0-1.1
Reaction time trials correct on left0.31.02.3-1.5-1.3-1.3-1.21.2-1.2-1.1-1.1-1.11.11.1-0.71.01.00.70.10.70.60.70.20.1
Reaction time trials on left0.30.92.2-1.5-1.3-1.2-1.11.2-1.2-1.1-1.1-1.11.11.1-0.71.01.00.70.10.70.60.70.20.0
Reaction time mean2.55.612.33.53.53.13.3-3.12.82.82.82.5-2.4-2.32.4-2.0-1.9-1.5-0.7-1.3-1.1-1.1-0.30.2
Reaction time mean AUC2.25.312.03.33.52.83.3-3.12.72.62.62.5-2.4-2.32.4-2.0-1.9-1.5-0.8-1.3-1.2-1.2-0.50.3
Median of all reaction times3.86.013.63.53.73.03.4-3.22.92.92.92.7-2.5-2.32.6-2.1-1.9-1.7-1.2-1.5-1.2-1.1-0.50.3
Reaction time omissions0.71.12.10.90.90.21.1-0.91.11.11.11.4-1.2-1.10.9-1.2-1.0-1.2-1.5-1.3-1.0-0.9-1.00.7
Reaction time false alarm rate1.52.03.7-1.7-1.6-1.2-1.81.6-1.8-1.9-1.9-1.31.51.5-1.51.31.41.50.51.21.11.20.6-0.9
Reaction time premature initiation rate0.10.10.20.20.2-0.00.3-0.30.40.30.40.3-0.4-0.40.3-0.4-0.4-0.3-0.3-0.2-0.4-0.4-0.3-0.1
Reaction time premature initiations0.00.10.4-0.5-0.4-0.6-0.20.2-0.2-0.2-0.1-0.20.10.2-0.10.10.1-0.0-0.30.2-0.10.0-0.2-0.1
Std. dev. reaction times1.34.410.53.22.92.92.9-2.92.52.42.52.1-2.2-2.22.0-1.8-2.0-1.20.1-0.9-1.0-1.3-0.20.0
Reaction time trials completed0.30.92.2-1.5-1.3-1.2-1.11.2-1.2-1.1-1.1-1.11.11.1-0.71.01.00.70.10.70.60.70.20.0
Reaction time trials AUC0.20.82.0-1.4-1.2-1.3-1.01.1-1.1-1.0-1.0-1.01.01.0-0.60.80.90.6-0.00.60.50.60.10.1
Run reversals in cocaine runway, females0.91.02.1-0.2-0.50.7-0.50.6-0.7-1.1-0.8-0.90.91.0-0.91.11.11.31.11.51.31.31.3-1.5
Run reversals in cocaine runway, males1.01.11.8-1.1-1.1-0.6-1.01.3-1.2-1.1-1.1-1.01.21.2-1.21.11.20.90.40.91.01.10.7-0.8
Latency to leave start box in cocaine runway2.02.86.7-2.6-2.0-2.3-2.21.7-2.2-2.3-2.2-1.81.81.7-1.21.41.41.30.71.10.80.80.30.2
Latency to leave start box in cocaine runway, F1.01.35.0-2.0-1.3-2.2-1.41.3-1.5-1.5-1.5-1.11.00.8-0.80.60.50.50.40.30.0-0.1-0.40.7
Latency to leave start box in cocaine runway, M3.12.94.2-1.8-1.7-0.8-1.91.4-1.9-2.0-2.0-1.92.02.0-1.21.92.01.80.91.81.71.91.3-0.9
Std. dev. time between licks in bursts1.63.07.5-2.7-2.3-2.6-2.22.2-2.2-2.3-2.2-1.61.71.7-1.51.41.51.0-0.11.00.70.9-0.00.2
Total sessions with >9 infusions2.43.05.0-1.9-2.0-1.1-2.01.9-2.2-2.2-2.2-2.01.81.8-1.81.71.61.71.31.71.31.31.0-1.0
Short access day 1 total inactive lever presses1.93.85.6-1.7-1.8-0.5-2.11.8-2.3-2.4-2.4-2.02.12.1-1.82.12.12.21.82.12.01.91.7-1.2
Short access day 10 total inactive lever presses0.00.00.3-0.3-0.6-0.3-0.30.3-0.10.0-0.0-0.30.20.2-0.10.20.20.10.0-0.10.10.10.00.0
Short access day 1 total infusions1.63.25.1-1.5-1.6-0.4-1.81.7-2.1-2.3-2.3-2.01.81.8-1.91.81.62.02.02.11.61.51.5-1.4
Short access day 10 total infusions0.61.04.2-0.8-0.6-1.8-0.4-0.2-0.00.0-0.00.8-0.5-0.50.9-0.8-0.6-1.1-2.0-1.1-1.2-1.0-1.71.3
Short access total infusions0.20.30.8-0.8-0.8-0.9-0.90.5-0.8-0.8-0.9-0.30.40.4-0.30.30.30.2-0.20.30.10.2-0.2-0.0
Short access day 1 locomotion2.13.44.9-1.7-1.8-0.6-1.91.8-2.2-2.2-2.2-2.12.02.0-1.92.01.92.01.82.01.81.71.6-1.3
Short access day 10 total locomotion0.10.61.0-1.0-1.0-0.7-0.90.8-1.0-0.8-0.8-0.80.80.8-0.50.80.80.70.20.70.60.70.4-0.3
Short access total locomotion2.03.04.8-1.9-1.7-1.0-1.81.8-2.2-2.2-2.2-1.81.91.9-1.71.81.81.71.01.81.61.61.2-1.1
One hour access (0.3 mA shock)0.30.31.9-0.1-0.1-0.50.2-0.10.30.50.50.6-0.4-0.30.5-0.4-0.3-0.8-1.4-0.6-0.6-0.3-0.80.6
Compulsive drug intake0.71.11.7-1.2-1.1-0.7-1.31.3-1.0-1.1-1.2-1.01.11.2-1.01.11.21.00.21.01.01.10.6-0.6
One hour access (shock baseline)0.20.50.90.40.3-0.10.6-0.60.50.80.80.8-0.7-0.70.7-0.7-0.7-0.9-0.9-0.9-0.8-0.7-0.80.7
Social response proportion0.30.40.90.90.90.80.8-0.80.80.90.70.8-0.6-0.60.5-0.5-0.4-0.5-0.4-0.6-0.2-0.3-0.1-0.3
Social responses0.10.10.3-0.2-0.20.1-0.30.2-0.4-0.3-0.4-0.20.30.4-0.20.40.50.3-0.00.40.40.50.3-0.5
Social time1.42.23.21.31.80.41.7-1.61.51.51.41.7-1.6-1.61.6-1.6-1.5-1.6-1.4-1.4-1.4-1.4-1.31.2
Soleus weight1.54.46.7-1.7-2.5-0.5-2.62.1-2.1-2.1-2.1-2.32.22.2-2.22.22.12.32.02.22.02.01.8-1.8
Bone: stiffness1.73.17.40.3-0.82.0-0.90.8-0.8-0.8-0.8-1.71.51.6-1.51.91.72.22.72.22.32.22.7-2.5
Tibialis anterior weight2.89.616.6-4.0-4.1-2.8-4.13.7-3.6-3.6-3.6-3.43.43.3-3.13.13.12.71.52.52.32.41.5-1.1
Time to tail flick, vehicle, before self-admin0.20.21.0-0.4-1.0-0.7-1.00.3-0.10.1-0.00.3-0.0-0.0-0.1-0.2-0.0-0.5-0.8-0.6-0.3-0.2-0.50.5
Time to tail flick, vehicle, after self-admin0.61.12.30.70.6-0.00.9-1.11.01.11.21.1-1.1-1.01.3-1.1-1.0-1.3-1.3-1.5-1.1-1.0-1.01.1
Time to tail flick, test, before self-admin2.12.43.5-1.7-1.5-0.9-1.71.8-1.8-1.7-1.7-1.51.81.8-1.61.71.91.50.61.41.51.71.1-1.1
Time to tail flick, test, after self-admin2.93.14.5-1.6-1.9-0.6-1.92.0-1.9-1.9-1.8-2.02.01.9-2.11.91.81.71.81.41.71.61.5-1.5
Delta time to tail flick, vehicle, before/after SA0.50.51.40.71.00.31.2-0.80.80.70.80.6-0.8-0.80.9-0.7-0.8-0.6-0.2-0.6-0.7-0.7-0.50.5
Delta time to tail flick, test, before/after SA0.10.10.80.3-0.10.20.1-0.20.30.30.30.0-0.3-0.50.1-0.3-0.7-0.30.9-0.4-0.4-0.7-0.10.1
Tibia length1.02.917.12.60.84.10.9-0.91.01.11.1-0.4-0.00.0-0.30.70.31.22.91.31.61.32.7-2.6
Ambulatory time before self-admin0.51.65.92.21.92.41.7-1.61.51.51.51.0-1.1-1.10.8-0.8-1.0-0.50.7-0.4-0.2-0.40.5-0.4
Ambulatory time after self-admin0.20.40.91.00.90.90.9-0.70.70.70.70.7-0.6-0.60.4-0.5-0.5-0.3-0.1-0.2-0.2-0.3-0.0-0.2
Bone: tissue strength0.00.00.20.20.20.20.2-0.1-0.0-0.1-0.1-0.10.0-0.00.10.0-0.10.10.40.10.1-0.00.20.0
Total heroin consumption2.12.53.31.41.70.51.7-1.81.61.71.71.8-1.7-1.71.8-1.7-1.7-1.6-1.2-1.7-1.5-1.6-1.31.3
Bone: trabecular number0.51.02.51.61.21.31.1-1.31.21.11.01.0-1.2-1.21.0-1.0-1.1-0.60.1-0.6-0.7-0.8-0.20.5
Bone: trabecular spacing0.71.01.8-0.8-0.6-0.1-0.61.0-1.0-0.9-0.9-1.01.21.2-1.11.21.31.10.61.01.21.31.0-1.4
Bone: trabecular thickness4.05.67.72.62.31.42.3-2.62.82.82.72.5-2.6-2.72.4-2.5-2.6-2.4-1.3-2.4-2.1-2.3-1.61.9
Bone: trabecular tissue density0.10.20.80.20.10.70.10.20.10.10.2-0.30.40.5-0.50.50.60.40.30.40.70.80.8-0.9
Water consumed over 24 hours0.10.10.7-0.5-0.1-0.9-0.20.1-0.1-0.1-0.10.1-0.1-0.20.2-0.3-0.3-0.4-0.4-0.4-0.5-0.5-0.60.4
Number of responses in last shaping day0.10.10.2-0.0-0.1-0.30.10.20.10.30.20.2-0.2-0.2-0.0-0.3-0.3-0.4-0.5-0.4-0.4-0.3-0.40.3