Hub : Genes

C9h2orf49

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression C9h2orf49 0.15 0.08 5.5e-12 0.05 0.07 0.1 0.1 2.5e-06 5.3e-08 3.7e-11 1.3e-11
2 Adipose mRNA stability C9h2orf49 0.12 0.07 5.2e-10 0.04 0.05 0.04 0.04 7.8e-05 1.3e-06 1.0e-05 1.2e-05
3 PL mRNA stability C9h2orf49 0.03 0.02 1.8e-03 0.02 0.02 0.01 0.01 3.7e-03 1.5e-03 2.1e-02 7.4e-03
4 Liver gene expression C9h2orf49 0.39 0.16 0.0e+00 0.18 0.21 0.21 0.2 3.3e-19 1.1e-22 1.4e-22 2.9e-22
5 pVTA mRNA stability C9h2orf49 0.18 0.12 1.8e-10 0.08 0.11 0.1 0.1 1.0e-06 1.8e-09 2.4e-08 1.1e-08
6 NAcc mRNA stability C9h2orf49 0.06 0.03 8.0e-11 0.06 0.07 0.06 0.06 3.6e-10 9.9e-11 7.9e-10 3.6e-10
7 Brain intron excision ratio chr9_52865638_52869347 0.03 0.02 3.6e-03 0.02 0.02 0.02 0.02 1.1e-02 2.7e-03 8.9e-03 9.0e-03
8 BLA mRNA stability C9h2orf49 0.05 0.04 4.2e-03 0.07 0.04 0.04 0.06 9.1e-05 4.5e-03 5.9e-03 4.9e-04
9 LHb gene expression C9h2orf49 0.49 0.15 6.3e-06 0.2 0.17 0.09 0.16 1.6e-05 9.2e-05 3.8e-03 9.9e-05
10 Brain mRNA stability C9h2orf49 0.14 0.09 3.6e-13 0.13 0.13 0.1 0.13 2.7e-12 2.9e-12 1.4e-09 3.7e-12
11 pVTA gene expression C9h2orf49 0.4 0.13 0.0e+00 0.26 0.27 0.26 0.26 1.2e-20 8.7e-22 5.1e-21 6.3e-21
12 Brain gene expression C9h2orf49 0.32 0.14 0.0e+00 0.11 0.17 0.16 0.16 2.9e-10 5.6e-16 8.8e-15 3.9e-15
13 BLA gene expression C9h2orf49 0.35 0.17 7.7e-07 0.13 0.11 0.11 0.12 3.3e-07 1.3e-06 2.1e-06 5.4e-07
14 PL gene expression C9h2orf49 0.16 0.07 5.6e-17 0.16 0.16 0.15 0.15 4.3e-17 1.4e-17 2.1e-16 2.2e-16
15 NAcc gene expression C9h2orf49 0.2 0.08 0.0e+00 0.14 0.15 0.15 0.15 2.4e-21 1.2e-22 4.4e-22 7.2e-22
16 IL gene expression C9h2orf49 0.51 0.17 2.0e-06 0.19 0.22 0.19 0.21 2.4e-05 6.3e-06 2.7e-05 7.5e-06
17 OFC gene expression C9h2orf49 0.33 0.18 2.6e-03 0.11 0.09 0.06 0.09 1.3e-03 3.1e-03 1.9e-02 3.9e-03
18 IC gene expression C9h2orf49 0.27 0.12 7.7e-07 0.1 0.13 0.13 0.13 9.0e-05 3.7e-06 6.1e-06 3.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density3.25.510.2-2.7-2.7-3.2-3.0-3.0-3.1-3.2-2.9-2.1-3.0-1.4-0.01.51.90.81.51.61.2
Area under the delay curve1.51.74.10.0-0.20.60.40.40.70.90.8-0.70.9-1.2-1.7-2.0-1.9-1.9-1.9-2.0-2.0
BMI with tail0.31.24.91.21.21.61.11.11.31.62.21.21.20.50.0-0.4-0.8-0.1-0.7-0.4-0.4
BMI without tail0.41.33.1-0.4-0.70.0-0.2-0.20.00.30.7-0.80.3-1.4-1.8-1.6-1.5-1.7-1.6-1.6-1.7
Body weight0.10.41.0-0.6-0.6-0.1-0.6-0.6-0.3-0.00.8-0.4-0.2-1.0-1.0-0.4-0.6-0.6-0.8-0.5-0.8
Weight adjusted by age1.21.94.21.51.71.11.31.31.00.81.11.70.62.11.91.21.11.61.41.11.5
Bone surface0.30.61.2-0.6-0.9-1.0-1.0-1.1-1.0-1.0-0.8-0.7-0.9-0.5-0.10.80.50.20.30.70.0
Bone volume1.62.85.1-1.9-2.0-2.2-2.2-2.2-2.3-2.3-1.9-1.6-2.1-1.1-0.11.21.30.50.91.10.6
Breakpoint value in progressive ratio session0.91.12.3-1.4-1.4-1.1-1.2-1.1-1.0-0.9-1.0-1.0-0.9-1.5-1.4-0.6-0.4-1.0-0.6-0.7-0.7
Number of licking bursts0.20.30.7-0.3-0.5-0.3-0.2-0.2-0.1-0.2-0.2-0.60.2-0.7-0.8-0.4-0.6-0.9-0.6-0.6-0.8
Context. condit. distance diff. score1.01.32.2-1.2-1.0-1.3-1.3-1.3-1.4-1.4-1.4-0.6-1.5-0.30.41.21.20.80.91.01.0
Locomotion velocity, session 10.00.00.1-0.4-0.2-0.0-0.1-0.1-0.00.00.2-0.1-0.0-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.1
Locomotion distance, session 10.91.22.91.41.51.31.31.31.21.11.21.71.01.41.00.40.20.70.40.40.5
Locomotion velocity, session 22.63.15.62.42.32.32.32.32.32.22.32.12.21.60.8-0.0-0.70.2-0.4-0.2-0.4
Locomotion distance, session 21.92.65.92.11.92.22.01.92.12.22.41.72.01.10.3-0.5-1.1-0.2-0.8-0.6-0.7
Locomotion velocity, session 30.20.20.6-0.1-0.0-0.3-0.2-0.1-0.3-0.4-0.40.3-0.50.30.50.80.70.60.70.60.7
Locomotion distance, session 30.10.20.5-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.7-0.1-0.7-0.10.00.30.40.20.30.30.5
Stereotopy head waving bouts, day 30.20.30.7-0.7-0.7-0.7-0.6-0.7-0.7-0.6-0.7-0.9-0.3-0.6-0.4-0.2-0.0-0.3-0.1-0.3-0.2
Stereotopy head waving duration, day 30.20.20.7-0.5-0.6-0.5-0.4-0.4-0.4-0.4-0.4-0.8-0.1-0.6-0.5-0.4-0.3-0.5-0.3-0.4-0.5
Locomotion velocity, session 71.92.14.51.91.91.31.61.61.21.00.92.01.02.11.81.20.81.41.11.21.1
Locomotion distance, session 70.60.71.81.31.11.11.11.11.11.00.91.11.00.90.50.2-0.30.2-0.10.0-0.0
Stereotopy head waving bouts, day 70.10.20.3-0.5-0.4-0.5-0.5-0.5-0.5-0.5-0.6-0.2-0.5-0.10.10.30.40.20.30.50.3
Stereotopy head waving duration, day 70.50.61.3-0.3-0.1-0.5-0.4-0.4-0.5-0.6-0.70.3-0.70.50.81.21.01.01.01.21.0
Locomotion velocity, session 81.11.43.40.30.70.00.20.2-0.0-0.2-0.01.2-0.41.41.71.81.61.81.61.71.7
Locomotion distance, session 80.71.02.20.81.00.60.50.50.40.40.51.40.11.31.41.50.91.51.01.31.2
Degree of sensitization distance1.31.32.51.41.11.41.41.31.41.41.50.71.60.4-0.2-0.7-1.1-0.7-1.0-0.9-1.1
Degree of sensitization stereotypy0.20.20.7-0.3-0.1-0.3-0.3-0.3-0.4-0.4-0.30.2-0.50.20.40.60.60.60.50.80.6
Conditioned locomotion0.60.71.7-1.3-1.2-0.8-1.2-1.3-0.9-0.6-0.3-1.1-0.8-1.3-1.0-0.3-0.3-0.5-0.6-0.3-0.3
Cocaine response after cond. corrected1.01.22.80.2-0.10.60.30.30.60.80.7-0.50.8-0.9-1.4-1.4-1.6-1.5-1.7-1.5-1.7
Cocaine response after cond. not corrected0.50.61.40.30.10.60.40.40.60.70.7-0.10.7-0.5-0.9-0.9-1.2-1.0-1.2-1.1-1.2
Cocaine response before conditioning0.81.02.00.70.70.20.40.40.1-0.1-0.01.4-0.11.31.41.31.21.41.41.21.3
Saline control response0.60.81.80.91.00.60.60.60.50.50.31.00.41.31.31.10.71.20.80.91.0
Bone: connectivity density0.71.12.0-1.1-1.3-1.4-1.4-1.4-1.4-1.4-1.2-1.1-1.2-0.9-0.30.60.50.00.30.50.1
Bone: cortical apparent density3.34.59.63.02.82.22.52.52.11.91.83.11.82.92.31.30.71.71.11.11.1
Bone: cortical area0.10.20.80.10.10.0-0.2-0.2-0.1-0.10.30.3-0.20.30.50.90.50.70.40.80.3
Bone: cortical porosity0.80.81.7-1.0-1.1-1.3-1.1-1.1-1.2-1.3-1.3-0.9-1.1-0.5-0.00.60.70.20.60.40.6
Bone: cortical porosity1.21.32.5-1.2-1.2-1.5-1.3-1.3-1.5-1.6-1.6-0.9-1.4-0.40.31.11.10.60.90.81.0
Bone: cortical thickness0.20.31.30.00.1-0.1-0.2-0.3-0.2-0.20.40.3-0.20.40.61.10.60.80.50.90.6
Bone: cortical thickness0.10.10.5-0.00.10.0-0.1-0.2-0.1-0.00.20.1-0.10.20.30.70.20.40.20.50.3
Bone: cortical tissue density3.14.39.42.92.72.12.42.42.01.81.73.11.72.82.31.40.81.81.31.21.2
Condit. Reinf. active minus inactive responses0.70.72.0-0.1-0.20.30.10.10.30.50.6-0.60.7-0.8-1.2-1.4-1.2-1.3-1.2-1.3-1.1
Condit. Reinf. active-inactive response ratio0.50.51.4-0.5-0.5-0.0-0.2-0.2-0.00.1-0.0-0.80.2-0.9-1.1-1.2-0.9-1.1-1.0-1.1-0.9
Condit. Reinf. active responses0.30.30.80.20.00.40.30.30.40.50.7-0.10.6-0.4-0.6-0.8-0.8-0.7-0.8-0.9-0.7
Condit. Reinf. inactive responses0.40.51.21.10.90.90.90.90.90.91.10.90.70.60.20.0-0.30.0-0.2-0.2-0.1
Incentive salience index mean0.10.10.3-0.3-0.3-0.1-0.2-0.2-0.1-0.00.3-0.40.1-0.5-0.5-0.4-0.4-0.5-0.4-0.5-0.3
Condit. Reinf. lever presses0.30.51.2-0.6-0.3-0.6-0.6-0.6-0.7-0.7-0.40.1-0.70.20.61.10.90.90.80.80.9
Condit. Reinf. active minus inactive responses0.50.61.2-0.7-0.8-0.5-0.5-0.5-0.4-0.3-0.6-1.1-0.2-1.0-1.1-1.0-0.7-1.1-0.8-1.0-0.8
Condit. Reinf. active-inactive response ratio1.31.53.2-1.8-1.6-1.4-1.4-1.4-1.3-1.2-1.5-1.7-1.2-1.5-1.1-0.9-0.1-0.8-0.4-0.6-0.3
Condit. Reinf. active responses0.40.51.20.2-0.00.40.30.30.40.50.5-0.40.6-0.6-0.9-0.9-1.1-1.1-1.1-1.1-1.1
Condit. Reinf. inactive responses1.21.53.81.91.51.51.61.61.51.41.81.51.41.20.70.4-0.40.2-0.10.1-0.2
Condit. Reinf. lever presses0.10.20.5-0.5-0.6-0.5-0.4-0.4-0.4-0.4-0.5-0.7-0.3-0.6-0.5-0.2-0.2-0.5-0.3-0.4-0.5
Condit. Reinf. lever reinforcers received0.50.71.50.50.10.60.50.50.70.70.7-0.30.8-0.5-0.9-1.0-1.2-1.2-1.2-1.2-1.2
Conditioned reinforcement - actives0.20.30.70.0-0.10.30.20.30.20.30.00.10.0-0.5-0.8-0.8-0.7-0.8-0.7-0.8-0.7
Conditioned reinforcement - inactives0.20.31.60.10.40.20.20.20.10.1-0.21.3-0.30.60.60.70.60.80.70.70.9
Conditioned locomotion0.50.62.31.01.10.90.80.90.60.70.61.50.21.00.80.50.30.80.50.60.6
Patch foraging indifference point 0 sec0.51.02.31.41.00.60.70.80.50.40.41.50.31.41.31.20.81.11.01.21.1
Patch foraging indifference point AUC0.30.40.80.60.50.80.60.60.70.90.80.40.8-0.0-0.4-0.7-0.8-0.5-0.7-0.4-0.8
Delay disc. indifference point, 0s delay1.01.12.61.31.41.01.21.21.00.80.61.60.81.51.20.70.51.00.70.80.7
Delay disc. indifference point, 16s delay1.71.93.9-1.2-1.4-0.7-0.8-0.9-0.6-0.4-0.4-1.8-0.3-2.0-2.0-1.8-1.4-1.9-1.6-1.8-1.7
Delay disc. indifference point, 2s delay0.70.71.70.1-0.00.60.30.30.50.70.40.00.6-0.7-1.1-1.3-1.3-1.2-1.3-1.3-1.3
Delay disc. indifference point, 24s delay0.10.10.4-0.3-0.2-0.10.0-0.00.00.0-0.2-0.30.2-0.4-0.5-0.6-0.4-0.6-0.4-0.5-0.6
Delay disc. indifference point, 4s delay0.30.30.70.50.60.80.70.60.80.80.80.50.70.2-0.1-0.3-0.5-0.2-0.5-0.4-0.4
Delay disc. indifference point, 8s delay0.91.12.7-0.1-0.30.20.20.20.40.50.4-0.80.7-1.0-1.4-1.6-1.5-1.6-1.5-1.6-1.6
Indifference point function ln k0.71.33.21.81.41.31.61.61.51.31.21.21.51.10.4-0.1-0.5-0.2-0.2-0.3-0.2
Indifference point function log k0.71.33.21.81.41.31.61.61.51.31.21.21.51.10.4-0.1-0.5-0.2-0.2-0.3-0.2
Patch foraging total patch changes 0 sec0.30.61.71.31.00.70.70.80.60.50.61.30.51.10.90.80.40.70.50.80.7
Patch foraging total patch changes 12 sec0.70.92.6-0.20.0-0.4-0.5-0.4-0.6-0.6-0.80.9-0.80.61.01.61.21.31.11.61.3
Patch foraging total patch changes 18 sec0.40.61.51.20.81.00.80.80.91.01.20.61.00.3-0.1-0.6-0.7-0.4-0.6-0.2-0.5
Patch foraging total patch changes 24 sec0.30.51.40.60.70.30.30.30.10.10.11.1-0.10.91.00.90.81.10.81.20.9
Patch foraging total patch changes 6 sec0.20.30.70.60.50.20.30.30.10.10.00.8-0.10.70.80.60.50.70.60.80.6
Patch foraging time to switch 0 sec0.40.81.8-1.1-0.7-1.1-0.9-0.9-1.1-1.2-1.3-0.4-1.1-0.10.40.71.10.71.00.70.9
Patch foraging water rate 0 sec0.40.92.20.40.10.70.40.40.70.91.1-0.30.7-0.7-1.2-1.1-1.4-1.3-1.5-1.0-1.4
Patch foraging water rate 12 sec0.20.50.90.70.40.70.70.70.80.80.8-0.20.8-0.0-0.4-0.9-0.9-0.7-0.8-0.8-0.8
Patch foraging water rate 18 sec0.00.00.20.40.1-0.00.30.40.20.0-0.20.10.10.20.0-0.0-0.1-0.20.0-0.1-0.0
Patch foraging water rate 24 sec0.10.20.40.70.50.40.60.60.60.40.5-0.00.60.30.1-0.4-0.3-0.3-0.2-0.3-0.2
Patch foraging water rate 6 sec0.70.91.51.10.60.91.11.11.11.01.0-0.21.20.1-0.5-1.1-1.1-1.0-0.9-1.1-1.2
Seeking ratio, delayed vs. immediate footshock0.70.91.9-1.4-1.1-1.2-1.3-1.3-1.3-1.2-0.8-0.6-1.3-0.6-0.20.50.80.40.60.50.6
Distance traveled before self-admin0.91.22.4-1.4-1.3-1.5-1.4-1.4-1.5-1.5-1.2-0.7-1.6-0.8-0.20.60.80.30.60.60.5
Distance traveled after self-admin3.64.47.6-1.9-1.7-2.5-2.3-2.2-2.6-2.7-2.7-0.6-2.8-0.30.92.12.41.72.22.12.0
Extensor digitorum longus weight5.220.440.26.35.95.96.05.95.85.75.75.25.54.42.2-0.8-1.70.6-0.8-0.9-0.8
Bone: elastic displacement1.01.22.8-1.2-1.4-1.1-1.1-1.0-1.0-0.9-0.9-1.7-0.7-1.5-1.4-0.9-0.5-1.2-0.7-0.9-0.7
Bone: elastic work0.81.12.1-1.4-1.4-1.3-1.4-1.4-1.3-1.2-0.9-1.4-1.2-1.2-0.70.10.2-0.3-0.10.0-0.0
Bone: endosteal estimation0.10.10.3-0.3-0.4-0.2-0.4-0.4-0.3-0.2-0.2-0.4-0.2-0.6-0.5-0.2-0.3-0.4-0.4-0.3-0.5
Bone: endosteal perimeter0.00.10.3-0.2-0.4-0.2-0.3-0.3-0.2-0.1-0.0-0.4-0.2-0.5-0.5-0.2-0.3-0.4-0.3-0.2-0.6
Epididymis fat weight0.20.51.20.80.60.80.70.70.80.91.10.50.90.1-0.3-0.6-0.7-0.5-0.6-0.8-0.8
Delta time in closed arm before/after self-admin0.10.10.3-0.2-0.3-0.2-0.0-0.0-0.1-0.1-0.2-0.20.0-0.4-0.4-0.5-0.3-0.6-0.3-0.6-0.5
Delta time in open arm before/after self-admin0.10.11.1-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.1-1.0-0.3-0.20.10.20.20.10.10.20.0
Diff in mean of infusions in LGA sessions0.60.71.5-1.2-1.1-0.8-1.1-1.1-0.8-0.7-0.5-0.9-0.8-1.2-0.9-0.4-0.2-0.6-0.4-0.4-0.4
Delay discount exponential model param1.61.84.30.10.3-0.5-0.3-0.3-0.6-0.8-0.80.7-0.91.21.82.01.92.02.02.12.0
Extinction: sum of active levers before priming3.23.58.2-2.9-2.5-2.1-2.7-2.7-2.4-1.9-1.8-1.9-2.4-2.3-1.5-0.30.1-0.6-0.4-0.2-0.2
Active lever presses in extinction session 60.90.92.2-0.2-0.20.50.00.00.30.60.7-0.40.4-1.1-1.4-1.4-1.4-1.3-1.5-1.5-1.3
Bone: final force0.40.62.1-0.10.2-0.2-0.3-0.4-0.4-0.30.10.5-0.60.61.01.41.01.20.91.20.9
Bone: final moment0.20.41.70.00.2-0.1-0.2-0.2-0.2-0.20.10.5-0.40.50.81.30.81.00.71.00.7
Food consumed during 24 hour testing period0.30.40.70.60.50.80.60.60.70.80.80.50.7-0.0-0.4-0.4-0.8-0.5-0.7-0.8-0.6
Glucose0.50.82.0-0.9-1.0-0.6-0.7-0.7-0.5-0.4-0.5-1.4-0.3-1.3-1.2-1.1-0.8-1.1-0.9-1.1-0.8
Heart weight0.20.30.50.40.30.50.50.50.60.60.70.20.7-0.1-0.4-0.6-0.7-0.6-0.6-0.7-0.7
Delay discount hyperbolic model param1.51.74.1-0.00.1-0.7-0.5-0.4-0.7-0.9-0.80.5-1.01.11.61.91.91.91.92.01.9
Intermittent access intake day 1-15 change0.20.40.8-0.1-0.4-0.7-0.5-0.4-0.7-0.8-0.90.4-0.70.00.30.60.80.50.80.70.7
Intermittent access intake escalation0.20.51.00.0-0.3-0.7-0.4-0.4-0.7-0.8-1.00.3-0.70.20.50.80.90.71.00.90.8
Intermittent access intake escalation 20.40.51.2-0.5-0.9-1.1-0.7-0.7-0.9-1.1-1.1-0.1-0.9-0.4-0.20.20.60.00.60.30.2
Intermitt. access day 1 inactive lever presses0.20.61.4-1.2-0.9-0.8-1.2-1.2-1.1-0.9-1.0-0.4-1.1-0.6-0.10.50.50.40.30.40.4
Intermitt. access day 15 inactive lever presses0.30.51.50.30.70.30.30.30.20.1-0.10.70.21.01.20.90.91.10.91.01.1
Intermitt. access escalation Index0.10.20.60.40.50.20.50.40.40.20.50.00.20.70.70.40.30.40.40.50.4
Intermittent access day 1 total infusions1.93.18.1-1.2-1.5-0.3-0.9-0.9-0.50.10.0-1.4-0.3-2.6-2.8-2.5-2.1-2.5-2.4-2.5-2.3
Intermittent access day 15 total infusions0.30.51.2-0.5-0.9-0.6-0.6-0.5-0.6-0.5-0.7-0.4-0.6-1.0-1.1-0.8-0.4-0.8-0.5-0.8-0.5
Intermittent access terminal intake (last 3 days)0.60.72.4-0.5-0.9-0.3-0.6-0.5-0.5-0.2-0.2-0.2-0.5-1.4-1.5-1.2-0.9-1.2-1.0-1.1-1.0
Intermittent access total infusions0.91.13.2-0.6-1.0-0.4-0.6-0.5-0.4-0.2-0.4-0.7-0.4-1.6-1.8-1.5-1.1-1.5-1.2-1.5-1.3
Intermittent access day 1 locomotion0.40.61.4-0.2-0.20.40.10.10.30.50.50.10.3-0.8-1.2-1.2-1.1-1.0-1.1-1.2-0.9
Intermittent access day 15 total locomotion0.30.52.51.00.80.80.91.00.80.80.51.60.70.60.2-0.0-0.10.10.10.00.1
Intermittent access total locomotion0.30.30.70.70.40.70.60.60.70.70.50.80.60.0-0.4-0.6-0.6-0.4-0.5-0.5-0.4
Intermittent access standard deviation0.40.81.6-1.1-1.3-1.1-1.2-1.2-1.2-1.1-1.2-0.5-1.2-1.1-0.7-0.10.2-0.3-0.0-0.1-0.3
Left kidney weight0.10.51.4-0.7-0.6-0.8-0.7-0.7-0.8-0.9-0.60.1-0.8-0.10.21.20.80.60.80.70.5
Right kidney weight0.31.44.70.40.60.00.00.1-0.1-0.20.11.6-0.41.31.52.21.51.81.61.91.5
Cocaine induced anxiety0.71.02.50.71.20.70.90.90.70.50.50.90.61.61.61.00.81.21.01.10.9
Post-drug Anxiety0.80.81.90.61.30.90.90.80.80.70.61.00.61.41.40.90.61.20.60.90.7
Baseline Anxiety0.40.51.5-0.4-0.30.3-0.2-0.20.20.50.3-0.30.1-0.9-1.1-1.0-1.1-0.9-1.2-1.0-1.1
Tail length0.93.57.2-2.2-2.5-1.8-2.0-1.9-1.7-1.5-1.3-2.5-1.3-2.7-2.5-1.3-1.0-1.9-1.3-1.3-1.7
Length with tail0.52.34.7-2.2-2.2-1.8-2.1-2.0-1.8-1.6-1.2-1.8-1.7-1.9-1.4-0.1-0.0-0.8-0.4-0.1-0.6
Length without tail0.00.10.5-0.2-0.0-0.1-0.3-0.3-0.2-0.10.20.3-0.40.10.30.70.40.50.30.70.5
Times rat made contact with spout1.61.84.0-1.2-1.5-0.9-1.0-1.0-0.8-0.6-0.3-1.8-0.4-2.0-2.0-1.4-1.2-1.8-1.5-1.6-1.6
Lifetime Intake0.70.92.5-0.3-0.8-0.1-0.4-0.3-0.20.1-0.2-0.5-0.2-1.3-1.6-1.4-1.1-1.4-1.2-1.3-1.1
Liver weight, left0.81.43.5-0.7-1.2-0.4-0.7-0.8-0.4-0.20.3-1.4-0.0-1.7-1.9-1.0-1.4-1.7-1.6-1.5-1.8
Liver weight, right0.91.54.2-1.7-1.6-1.1-1.4-1.5-1.1-0.9-0.5-2.1-1.0-1.8-1.4-0.7-0.6-1.0-1.0-0.8-0.9
Locomotor activity0.10.20.4-0.5-0.7-0.6-0.5-0.5-0.6-0.5-0.4-0.6-0.5-0.6-0.5-0.4-0.0-0.3-0.1-0.2-0.3
Locomotor testing distance0.61.12.1-1.2-1.2-1.5-1.3-1.3-1.4-1.5-1.4-1.1-1.4-0.7-0.10.40.80.20.70.60.5
Locomotor testing rearing0.91.74.1-1.2-1.1-1.6-1.4-1.3-1.6-1.7-2.0-0.7-1.6-0.20.61.31.50.91.31.31.2
Locomotion in novel chamber3.34.28.72.62.42.82.52.52.72.83.02.42.51.30.2-0.7-1.4-0.3-1.1-0.6-0.9
Locomotion in novel chamber post-restriction0.71.22.71.31.41.71.31.31.51.61.61.41.30.70.2-0.1-0.70.0-0.6-0.1-0.3
Fecal boli incidents, locomotor time 10.71.01.90.80.71.20.90.91.21.31.30.21.40.1-0.5-0.8-1.2-0.8-1.2-1.0-1.0
Change in fecal boli incidents, locomotor task0.20.20.6-0.4-0.4-0.5-0.6-0.6-0.5-0.5-0.70.2-0.8-0.20.10.50.50.40.30.50.4
Time >=10cm from walls, locomotor time 12.52.75.62.02.22.12.42.32.32.01.71.52.41.70.9-0.4-0.7-0.0-0.3-0.5-0.4
Bouts of movement, locomotor time 15.15.89.72.01.82.82.32.32.83.13.00.33.10.0-1.3-2.6-3.0-2.1-2.9-2.5-2.6
Total resting periods, locomotor time 15.05.610.02.22.02.92.42.42.93.23.10.63.00.4-1.0-2.3-2.8-1.8-2.6-2.1-2.3
Rest time, locomotor task time 11.72.14.8-0.7-0.90.1-0.4-0.40.10.50.4-1.50.3-1.8-2.2-2.0-2.0-2.1-2.2-2.0-1.9
Distance moved, locomotor task time 10.10.10.40.60.40.20.50.60.30.10.10.70.40.50.40.10.20.20.40.10.2
Vertical activity count, locomotor time 10.41.02.7-0.3-0.1-0.8-0.4-0.4-0.7-1.0-1.00.3-0.80.81.21.21.61.31.61.31.5
Time >=10cm from walls, locomotor time 20.00.00.1-0.3-0.2-0.1-0.1-0.10.0-0.0-0.0-0.10.1-0.2-0.3-0.3-0.2-0.3-0.2-0.3-0.2
Bouts of movement, locomotor time 21.01.53.11.71.31.71.41.41.61.71.81.01.50.5-0.2-0.8-1.1-0.5-0.9-0.6-0.8
Total resting periods, locomotor time 20.71.22.61.61.21.51.31.31.41.51.51.01.20.5-0.2-0.7-0.9-0.4-0.8-0.4-0.7
Rest time, locomotor task time 20.10.10.4-0.2-0.4-0.3-0.3-0.3-0.3-0.3-0.6-0.6-0.3-0.4-0.3-0.3-0.1-0.3-0.2-0.1-0.2
Distance moved, locomotor task time 20.70.81.61.00.91.01.21.21.21.11.20.71.30.5-0.1-0.6-0.7-0.4-0.5-0.8-0.5
Vertical activity count, locomotor time 20.30.30.80.40.80.60.50.50.50.50.90.80.40.80.70.40.30.70.40.30.6
Light reinforcement 11.33.27.32.72.42.52.22.22.12.32.32.61.91.71.00.1-0.60.5-0.30.00.1
Light reinforcement 20.40.51.41.00.81.10.70.70.81.01.21.00.80.3-0.1-0.3-0.7-0.2-0.6-0.4-0.4
Bone: marrow area0.00.10.2-0.2-0.3-0.1-0.3-0.3-0.2-0.1-0.2-0.3-0.1-0.5-0.4-0.2-0.3-0.4-0.4-0.3-0.4
Bone: maximum diameter0.10.30.6-0.6-0.6-0.6-0.8-0.8-0.7-0.6-0.3-0.5-0.7-0.4-0.10.50.30.20.20.4-0.0
Bone: maximum force0.20.41.50.00.2-0.0-0.2-0.2-0.2-0.10.30.5-0.30.50.81.20.81.00.71.00.6
Bone: maximum moment0.10.21.10.20.30.1-0.0-0.1-0.00.00.40.5-0.10.50.71.10.50.80.50.80.5
Mean time between licks in bursts0.61.53.31.71.71.61.61.61.51.41.31.81.31.40.90.4-0.10.50.10.20.1
Mean num. licks in bursts0.00.10.20.10.00.20.00.00.10.30.4-0.00.0-0.2-0.3-0.5-0.4-0.3-0.4-0.5-0.2
Cd content in liver2.52.86.0-2.4-2.3-1.9-2.1-2.1-1.9-1.7-1.8-2.1-1.9-2.2-1.6-0.5-0.1-1.0-0.5-0.4-0.4
Co content in liver0.81.01.8-1.3-1.3-1.1-1.1-1.1-1.0-0.9-0.9-1.3-1.0-1.3-1.1-0.5-0.3-0.8-0.4-0.6-0.5
Cu content in liver0.10.20.3-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.3-0.5-0.30.0-0.0-0.2-0.1-0.2-0.0
Fe content in liver2.32.85.1-2.2-2.0-2.2-2.3-2.2-2.2-2.2-1.9-1.8-2.1-1.3-0.30.81.10.30.70.81.0
K content in liver1.11.12.41.51.41.31.41.31.21.21.21.11.31.30.90.2-0.10.50.10.00.1
Mg content in liver0.30.30.60.70.70.40.60.50.40.30.20.60.50.80.70.50.30.50.40.30.4
Mn content in liver0.60.61.40.91.00.60.80.70.60.50.40.90.51.21.20.30.61.00.80.61.0
Na content in liver1.21.32.7-0.7-0.6-1.2-0.9-0.9-1.2-1.4-1.0-0.3-1.20.31.01.71.51.21.41.31.3
Rb content in liver2.93.46.52.52.32.52.32.22.42.52.42.02.31.50.6-0.7-1.00.1-0.6-0.6-0.5
Se content in liver0.20.20.50.40.20.60.30.30.50.60.70.20.6-0.2-0.4-0.5-0.6-0.4-0.7-0.6-0.4
Sr content in liver0.20.20.60.2-0.10.10.10.10.20.20.0-0.40.3-0.4-0.6-0.6-0.6-0.7-0.6-0.6-0.4
Zn content in liver0.00.00.2-0.2-0.3-0.3-0.2-0.2-0.2-0.3-0.5-0.1-0.2-0.2-0.10.20.1-0.10.0-0.0-0.0
Bone: minimum diameter0.20.31.00.70.70.70.50.40.50.61.00.70.30.60.50.50.10.50.10.4-0.1
Time in familiar zone, hab. session 11.41.43.1-1.2-1.3-0.6-1.0-1.0-0.7-0.4-0.2-1.6-0.4-1.8-1.7-1.2-1.1-1.5-1.4-1.1-1.4
Time in novel zone, hab. session 10.20.20.5-0.6-0.5-0.7-0.4-0.4-0.6-0.7-0.7-0.4-0.6-0.2-0.1-0.00.40.00.40.00.2
Total zone transitions, hab. session 11.31.94.10.81.10.20.60.60.2-0.1-0.21.6-0.21.82.01.91.72.01.91.91.8
Total locomotion distance, hab. session 10.71.02.11.41.31.21.21.31.11.11.01.51.01.20.80.40.00.50.20.30.3
Locomotion velocity, hab. session 10.81.22.81.41.41.11.21.21.10.90.81.70.81.51.20.80.41.00.60.70.7
Time in familiar zone, hab. session 20.20.30.5-0.7-0.7-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.5-0.6-0.5-0.1-0.0-0.4-0.1-0.1-0.2
Time in novel zone, hab. session 20.00.00.0-0.1-0.00.0-0.1-0.1-0.10.00.2-0.1-0.1-0.00.1-0.00.00.1-0.00.00.1
Total zone transitions, hab. session 20.10.21.00.40.40.60.40.40.50.61.00.60.50.1-0.2-0.3-0.3-0.1-0.3-0.1-0.1
Total locomotion distance, hab. session 21.31.63.21.31.01.51.41.41.51.61.80.81.60.2-0.6-1.2-1.4-1.0-1.2-1.3-1.2
Locomotion velocity, hab. session 21.01.42.71.41.11.41.41.41.51.51.61.01.50.5-0.3-0.8-1.1-0.6-0.8-0.9-0.8
Novel to familiar place preference ratio1.41.63.6-0.7-1.0-0.2-0.6-0.6-0.20.00.1-1.50.2-1.7-1.9-1.5-1.6-1.8-1.8-1.6-1.8
Novelty place preference1.41.53.4-0.8-1.1-0.3-0.6-0.7-0.3-0.00.1-1.50.2-1.7-1.8-1.5-1.5-1.8-1.7-1.5-1.7
Time in novel zone, NPP test1.71.84.1-1.0-1.3-0.5-0.9-0.9-0.5-0.2-0.1-1.8-0.0-2.0-2.0-1.6-1.5-1.9-1.8-1.6-1.8
Total zone transitions, NPP test0.40.61.71.01.01.01.01.01.00.91.11.30.80.90.50.2-0.00.30.20.10.2
Total locomotion distance, NPP test0.71.01.91.31.21.31.41.41.31.21.31.11.30.70.1-0.4-0.7-0.3-0.4-0.6-0.5
Locomotion velocity, NPP test1.21.63.11.81.71.61.81.81.61.51.51.61.61.30.6-0.0-0.40.1-0.1-0.3-0.1
Intraocular pressure1.11.63.31.31.51.81.51.51.71.81.61.41.60.7-0.0-0.6-1.1-0.4-0.9-0.8-0.6
Delta distance traveled before/after self-admin0.50.51.2-0.10.0-0.4-0.3-0.2-0.4-0.6-1.00.3-0.50.60.91.01.11.01.11.11.0
Delta ambulatory time before/after self-admin0.30.40.90.10.2-0.2-0.1-0.0-0.2-0.3-0.70.5-0.40.60.80.80.90.90.90.90.9
Parametrial fat weight0.00.10.5-0.4-0.10.2-0.2-0.20.00.30.7-0.2-0.2-0.4-0.3-0.2-0.3-0.1-0.4-0.2-0.2
Pavlov. Cond. lever latency0.70.91.71.00.61.01.01.01.11.10.80.11.1-0.0-0.6-1.3-1.3-1.0-1.1-0.9-1.1
Pavlov. Cond. magazine entry latency0.10.10.4-0.6-0.4-0.4-0.5-0.5-0.5-0.4-0.3-0.5-0.2-0.4-0.2-0.30.1-0.00.0-0.30.1
Pavlov. Cond. change in total contacts0.10.10.4-0.2-0.10.2-0.1-0.10.10.20.3-0.20.2-0.4-0.4-0.4-0.5-0.4-0.5-0.6-0.4
Pavlov. Cond. index score0.30.41.0-1.0-0.8-0.8-0.9-0.9-0.9-0.8-0.5-0.6-0.7-0.6-0.20.20.40.10.2-0.00.2
Pavlov. Cond. latency score0.40.51.2-1.1-0.9-1.0-1.0-1.0-1.0-1.0-0.6-0.6-0.9-0.5-0.00.50.60.30.40.20.5
Pavlov. Cond. lever contacts0.40.51.0-0.8-0.4-0.7-0.7-0.7-0.8-0.8-0.40.0-0.80.10.51.01.00.80.90.70.9
Pavlov. Cond. magazine entry number0.40.51.21.10.91.00.91.01.01.00.90.90.70.60.20.0-0.4-0.0-0.30.1-0.3
Pavlov. Cond. intertrial magazine entries0.50.61.30.40.10.60.50.40.70.71.1-0.00.7-0.4-0.9-0.6-1.1-1.0-1.1-1.0-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.7-0.6-0.5-0.6-0.7-0.5-0.5-0.2-0.5-0.3-0.6-0.3-0.10.0-0.1-0.1-0.3-0.1
Pavlov. Cond. response bias0.20.30.7-0.8-0.7-0.7-0.8-0.8-0.7-0.7-0.3-0.6-0.5-0.5-0.10.10.30.10.20.00.3
Pavlov. Cond. lever latency0.20.30.70.40.40.70.40.40.60.70.80.20.7-0.0-0.3-0.5-0.6-0.4-0.6-0.4-0.5
Pavlov. Cond. magazine entry latency0.91.12.70.00.2-0.5-0.2-0.1-0.5-0.8-1.00.6-0.81.01.41.31.61.51.61.31.5
Pavlov. Cond. change in total contacts0.20.40.7-0.8-0.8-0.8-0.7-0.7-0.8-0.8-0.9-0.7-0.7-0.5-0.20.30.2-0.10.10.1-0.0
Pavlov. Cond. index score0.30.40.9-0.5-0.4-0.7-0.6-0.6-0.7-0.8-0.9-0.1-0.90.00.40.60.80.60.70.50.7
Pavlov. Cond. latency score0.20.20.5-0.2-0.1-0.5-0.3-0.3-0.5-0.5-0.70.1-0.60.20.50.60.70.60.70.50.6
Pavlov. Cond. lever contacts0.40.51.3-0.9-0.8-1.0-0.8-0.7-0.9-1.0-1.2-0.6-1.0-0.4-0.00.30.60.10.50.20.3
Pavlov. Cond. magazine entry number0.60.81.80.30.10.70.40.30.70.91.3-0.20.9-0.5-1.0-1.0-1.3-1.1-1.3-0.9-1.2
Pavlov. Cond. intertrial magazine entries1.72.54.81.81.52.01.81.82.02.12.21.12.00.5-0.4-1.3-1.6-0.9-1.3-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.3-0.2-0.5-0.4-0.4-0.5-0.6-0.7-0.0-0.70.20.50.60.70.60.70.50.6
Pavlov. Cond. response bias0.91.22.3-0.9-0.7-1.3-0.9-0.9-1.2-1.4-1.5-0.3-1.40.20.81.21.51.01.41.11.2
Time in closed arm before self-admin1.01.22.8-1.4-1.5-1.0-1.3-1.3-1.0-0.8-0.7-1.6-0.8-1.7-1.4-0.8-0.6-1.0-0.8-0.8-0.8
Time in closed arm after self-admin0.80.81.7-1.1-1.1-1.2-1.2-1.1-1.2-1.2-1.2-0.7-1.3-0.7-0.30.50.60.20.50.50.4
Time in open arm before self-admin0.80.92.31.11.21.21.21.21.21.11.01.51.10.80.3-0.2-0.40.0-0.2-0.2-0.1
Time in open arm after self-admin0.10.10.40.10.2-0.10.10.0-0.0-0.1-0.1-0.1-0.00.50.70.50.50.60.50.60.5
Bone: periosteal estimation0.10.20.5-0.4-0.5-0.5-0.7-0.7-0.6-0.5-0.2-0.3-0.6-0.3-0.00.60.30.20.10.40.0
Bone: periosteal perimeter0.20.30.8-0.7-0.8-0.5-0.7-0.8-0.6-0.4-0.2-0.8-0.5-0.9-0.7-0.1-0.3-0.5-0.4-0.2-0.7
Bone: post-yield work0.30.51.60.10.3-0.10.0-0.0-0.2-0.3-0.00.7-0.30.81.01.31.01.11.01.00.7
Progressive ratio test 1 active lever presses0.60.71.40.70.30.90.60.60.71.01.10.40.8-0.4-1.0-1.1-1.2-0.9-1.1-1.1-0.9
Progressive ratio test 1 breakpoint0.60.71.50.50.20.80.50.50.60.91.00.30.7-0.5-1.1-1.2-1.2-1.0-1.2-1.2-1.0
Progressive ratio test 1 inactive lever presses0.20.30.9-0.10.0-0.1-0.4-0.4-0.4-0.2-0.20.8-0.70.20.40.80.70.80.60.81.0
Progressive ratio test 2 active lever presses0.40.41.81.10.70.70.91.00.70.70.51.30.50.50.0-0.1-0.2-0.10.0-0.10.0
Progressive ratio test 2 breakpoint0.50.51.81.20.80.80.91.10.80.80.61.30.60.5-0.0-0.1-0.3-0.2-0.1-0.2-0.0
Progressive ratio test 2 inactive lever presses0.30.41.5-0.00.2-0.1-0.10.0-0.2-0.2-0.51.2-0.50.50.60.80.80.90.90.81.0
Incentive Sensitization - Responses0.30.51.00.80.50.10.50.60.3-0.1-0.30.90.01.00.90.80.70.71.00.80.8
Incentive Sensitization - Breakpoint0.40.61.30.90.70.20.60.70.30.0-0.31.10.11.11.00.90.80.81.00.90.9
Sum of active levers in priming session hrs 5-62.01.94.2-1.5-1.8-1.2-1.3-1.2-1.1-0.9-0.8-1.4-0.9-2.0-2.0-1.3-0.9-1.7-1.1-1.3-1.3
Progressive ratio1.52.34.31.51.11.81.51.41.81.92.10.41.80.1-0.8-1.8-1.8-1.3-1.6-1.5-1.5
Food seeking constrained by brief footshock0.10.20.40.60.60.50.60.60.50.50.20.40.50.50.3-0.5-0.00.10.1-0.10.1
Seeking ratio, punishment vs. effort0.60.91.7-0.7-0.4-0.9-0.7-0.7-1.0-1.1-1.30.1-1.00.30.81.11.31.01.21.11.2
Retroperitoneal fat weight0.20.82.51.21.11.20.90.80.91.11.61.40.80.70.40.2-0.20.4-0.20.1-0.1
Reaction time number correct0.61.22.61.61.41.51.41.41.41.41.41.21.31.00.5-0.2-0.50.1-0.3-0.2-0.0
Reaction time mean minus median0.40.91.8-1.3-1.3-1.3-1.1-1.1-1.1-1.2-1.3-1.2-1.0-1.1-0.7-0.10.2-0.40.1-0.3-0.3
Reaction time mean minus median AUC0.30.71.6-1.0-1.1-1.2-0.9-0.9-1.0-1.1-1.3-0.9-0.9-0.8-0.6-0.00.3-0.30.2-0.2-0.3
Reaction time num false alarms1.01.43.01.71.51.61.51.51.51.51.51.61.21.10.5-0.2-0.50.2-0.2-0.2-0.1
Reaction time num false alarms AUC1.32.04.22.01.91.91.81.81.71.71.81.91.41.40.80.0-0.40.4-0.1-0.1-0.0
Reaction time trials correct on left0.61.22.61.61.41.51.41.41.41.41.41.21.31.00.5-0.2-0.50.1-0.3-0.2-0.0
Reaction time trials on left0.61.12.41.61.41.41.41.31.41.31.31.11.31.00.5-0.2-0.50.1-0.3-0.2-0.0
Reaction time mean1.52.45.1-2.3-2.1-2.0-1.9-1.9-1.8-1.8-1.8-2.1-1.7-1.8-1.2-0.30.2-0.7-0.1-0.4-0.4
Reaction time mean AUC1.11.83.7-1.9-1.8-1.6-1.6-1.6-1.5-1.5-1.4-1.9-1.3-1.7-1.2-0.5-0.1-0.8-0.3-0.5-0.6
Median of all reaction times1.72.45.4-2.3-2.1-1.9-1.9-1.9-1.8-1.7-1.6-2.2-1.7-1.9-1.3-0.40.0-0.8-0.3-0.4-0.5
Reaction time omissions0.40.62.1-0.9-0.9-1.1-0.9-0.8-1.0-1.1-1.4-0.5-1.0-0.4-0.10.70.60.20.60.30.4
Reaction time false alarm rate0.40.61.41.11.00.91.00.90.90.80.91.20.60.80.60.2-0.00.40.10.10.1
Reaction time premature initiation rate0.10.20.3-0.6-0.3-0.5-0.5-0.5-0.5-0.5-0.4-0.2-0.5-0.20.10.20.50.30.40.30.4
Reaction time premature initiations0.00.00.10.20.20.20.10.10.10.10.20.20.10.20.30.10.20.30.20.20.3
Std. dev. reaction times0.81.43.2-1.6-1.5-1.7-1.4-1.3-1.5-1.6-1.8-1.5-1.4-1.1-0.60.20.5-0.30.40.0-0.1
Reaction time trials completed0.61.12.41.61.41.41.41.31.41.31.31.11.31.00.5-0.2-0.50.1-0.3-0.2-0.0
Reaction time trials AUC0.51.02.21.51.31.41.31.31.31.31.31.11.30.90.5-0.2-0.50.1-0.3-0.2-0.1
Run reversals in cocaine runway, females0.40.41.00.90.90.80.90.80.90.81.00.30.80.70.4-0.1-0.20.1-0.1-0.0-0.2
Run reversals in cocaine runway, males0.20.20.6-0.1-0.10.30.00.10.10.30.20.70.1-0.4-0.6-0.4-0.5-0.5-0.5-0.4-0.4
Latency to leave start box in cocaine runway1.31.53.31.11.51.11.01.00.90.91.01.80.51.71.61.40.81.50.91.21.3
Latency to leave start box in cocaine runway, F1.21.43.50.41.00.30.40.40.20.10.01.1-0.11.61.91.61.41.81.51.61.7
Latency to leave start box in cocaine runway, M2.22.04.52.01.81.91.71.71.71.82.12.11.61.30.60.3-0.60.3-0.3-0.1-0.1
Std. dev. time between licks in bursts0.50.71.70.90.81.10.90.91.11.11.30.41.10.2-0.2-0.4-0.9-0.5-0.8-0.6-0.8
Total sessions with >9 infusions0.40.40.80.70.40.80.40.40.60.90.90.40.5-0.2-0.6-0.8-0.9-0.6-0.9-0.8-0.5
Short access day 1 total inactive lever presses0.40.51.80.90.80.60.60.60.40.50.31.30.40.90.70.60.40.70.50.50.8
Short access day 10 total inactive lever presses0.20.50.9-0.5-0.4-0.7-0.7-0.6-0.7-0.8-0.90.1-0.70.10.50.90.90.80.80.90.8
Short access day 1 total infusions0.50.62.11.10.91.10.91.00.91.00.91.50.70.4-0.2-0.4-0.6-0.2-0.4-0.4-0.1
Short access day 10 total infusions2.43.07.5-0.1-0.70.4-0.0-0.00.30.80.8-1.00.7-2.0-2.6-2.7-2.4-2.6-2.5-2.7-2.5
Short access total infusions1.01.23.00.3-0.20.60.10.20.40.80.8-0.20.5-1.1-1.7-1.7-1.6-1.6-1.7-1.7-1.4
Short access day 1 locomotion0.70.91.81.11.31.31.11.21.21.31.21.31.00.90.4-0.1-0.40.2-0.2-0.00.2
Short access day 10 total locomotion0.10.10.30.2-0.10.10.10.10.00.1-0.00.20.3-0.3-0.5-0.5-0.4-0.5-0.4-0.5-0.5
Short access total locomotion0.81.02.01.41.31.41.31.31.31.41.21.21.30.80.3-0.3-0.60.0-0.4-0.3-0.1
One hour access (0.3 mA shock)2.93.39.5-1.1-1.8-0.6-1.2-1.1-0.7-0.2-0.0-1.4-0.6-2.8-3.1-2.3-2.1-2.6-2.3-2.4-2.3
Compulsive drug intake0.30.41.00.60.80.40.80.70.60.30.20.40.51.00.90.50.40.50.50.40.5
One hour access (shock baseline)1.52.36.3-1.0-1.6-0.7-1.1-1.0-0.8-0.4-0.3-1.1-0.7-2.3-2.5-1.9-1.6-2.1-1.8-1.9-1.8
Social response proportion0.40.51.2-1.1-0.9-0.7-1.0-0.9-0.8-0.6-0.5-0.6-0.6-1.0-0.8-0.5-0.1-0.4-0.3-0.4-0.2
Social responses1.01.32.9-1.7-1.6-1.3-1.5-1.5-1.4-1.2-1.1-1.3-1.2-1.5-1.0-0.5-0.0-0.5-0.3-0.4-0.4
Social time3.34.58.6-2.8-2.8-2.9-2.9-2.9-2.9-2.8-2.6-2.0-2.6-1.9-0.90.81.10.00.70.90.6
Soleus weight1.02.95.82.42.22.12.22.22.11.92.32.11.91.81.10.2-0.30.50.10.20.0
Bone: stiffness0.71.23.20.40.80.30.20.20.10.10.31.2-0.21.31.71.81.31.81.31.51.3
Tibialis anterior weight2.79.018.84.34.03.84.24.23.93.63.13.63.73.01.6-0.7-1.10.3-0.3-0.4-0.5
Time to tail flick, vehicle, before self-admin0.60.61.5-0.9-1.0-0.7-1.0-1.0-0.7-0.5-0.4-1.2-0.6-1.1-0.8-0.4-0.4-0.6-0.6-0.4-0.6
Time to tail flick, vehicle, after self-admin0.20.31.2-0.8-0.7-0.7-0.7-0.8-0.6-0.6-0.5-1.1-0.4-0.5-0.20.00.1-0.1-0.10.1-0.1
Time to tail flick, test, before self-admin2.93.06.62.62.12.12.52.62.32.02.01.72.31.50.4-0.7-0.9-0.4-0.4-0.6-0.6
Time to tail flick, test, after self-admin0.70.82.31.01.01.30.90.81.11.31.50.50.90.3-0.1-0.5-0.8-0.2-0.8-0.4-0.5
Delta time to tail flick, vehicle, before/after SA0.10.00.20.20.30.10.30.30.20.10.10.00.30.40.30.20.10.20.20.20.2
Delta time to tail flick, test, before/after SA0.91.02.8-1.5-1.2-0.9-1.6-1.7-1.3-0.9-0.6-1.2-1.3-1.1-0.50.20.20.1-0.30.10.1
Tibia length0.51.22.3-1.2-0.9-1.2-1.4-1.4-1.3-1.3-0.9-0.7-1.4-0.20.51.51.21.00.91.30.8
Ambulatory time before self-admin0.60.91.8-1.3-1.2-1.3-1.3-1.3-1.3-1.3-1.0-0.7-1.4-0.8-0.30.30.60.10.40.40.3
Ambulatory time after self-admin1.92.24.0-1.1-1.0-1.7-1.4-1.4-1.7-1.9-2.00.1-1.90.00.81.61.91.31.71.71.6
Bone: tissue strength0.10.10.40.30.30.30.30.30.30.30.60.30.30.20.10.1-0.10.0-0.1-0.1-0.0
Total heroin consumption2.83.28.1-1.5-1.8-0.7-1.3-1.3-0.7-0.3-0.2-1.8-0.4-2.7-2.8-2.2-2.0-2.4-2.3-2.3-2.2
Bone: trabecular number3.05.09.1-2.5-2.4-2.9-2.8-2.8-3.0-3.0-2.7-1.8-3.0-1.10.31.72.01.11.61.71.4
Bone: trabecular spacing1.52.03.91.71.82.01.81.81.91.91.71.81.81.20.5-0.4-0.70.1-0.4-0.4-0.3
Bone: trabecular thickness3.84.88.9-2.9-2.8-3.0-2.8-2.8-2.9-2.9-2.6-2.6-2.8-1.8-0.70.61.20.00.70.60.4
Bone: trabecular tissue density0.60.91.90.70.80.20.60.60.3-0.0-0.41.1-0.01.41.41.11.21.31.41.31.2
Water consumed over 24 hours0.10.20.5-0.3-0.4-0.1-0.3-0.3-0.10.00.3-0.3-0.1-0.6-0.7-0.4-0.5-0.5-0.6-0.6-0.4
Number of responses in last shaping day0.10.10.3-0.1-0.3-0.3-0.4-0.4-0.4-0.3-0.6-0.1-0.3-0.2-0.0-0.00.20.10.0-0.00.5