Hub : Genes

C7h22orf23

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression C7h22orf23 0.03 0.02 2.7e-03 0.02 0.02 0.02 0.02 1.5e-03 1.8e-03 3.3e-03 5.1e-03
2 NAcc intron excision ratio chr7_112586431_112591022 0.04 0.03 9.5e-05 0.01 0.03 0.03 0.03 3.7e-03 1.7e-05 4.6e-05 1.0e-04
3 PL intron excision ratio chr7_112586431_112591022 0.09 0.04 1.1e-09 0.1 0.1 0.09 0.09 1.6e-10 1.4e-10 7.9e-10 3.1e-10
4 pVTA intron excision ratio chr7_112586431_112591022 0.04 0.02 4.3e-03 0.02 0.03 0.01 0.02 4.8e-03 1.6e-03 8.1e-02 6.5e-03
5 NAcc gene expression C7h22orf23 0.03 0.02 7.5e-04 0.02 0.02 0.02 0.02 1.4e-03 1.3e-03 8.5e-04 8.6e-04
6 IC intron excision ratio chr7_112586431_112591022 0.31 0.13 1.2e-07 0.18 0.16 0.15 0.16 3.1e-08 2.8e-07 6.0e-07 2.5e-07
7 Brain intron excision ratio chr7_112586431_112591022 0.08 0.04 1.5e-06 0.09 0.07 0.05 0.08 2.4e-08 3.7e-07 1.0e-05 1.4e-07
8 PL mRNA stability C7h22orf23 0.04 0.02 6.8e-04 0.04 0.03 0.03 0.03 5.8e-05 8.3e-04 3.7e-04 7.4e-04
9 BLA intron excision ratio chr7_112586431_112591022 0.08 0.05 5.3e-03 0.05 0.04 0.04 0.04 8.2e-04 3.0e-03 4.9e-03 2.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.00.1-0.10.3-0.40.0-0.4-0.2-0.00.0-0.0
Area under the delay curve1.51.73.4-1.71.81.30.7-1.21.21.21.21.2
BMI with tail0.20.61.80.8-0.3-1.30.3-1.0-0.7-0.8-0.8-0.7
BMI without tail0.82.44.40.9-1.6-2.1-1.10.6-1.7-1.7-1.7-1.7
Body weight0.73.27.62.8-1.8-2.4-0.50.4-1.7-1.8-1.8-1.7
Weight adjusted by age0.30.42.11.4-0.6-0.20.00.3-0.0-0.6-0.6-0.6
Bone surface0.20.40.9-0.20.30.80.4-0.00.50.90.90.9
Bone volume0.00.00.1-0.4-0.00.0-0.10.1-0.10.30.30.3
Breakpoint value in progressive ratio session0.20.30.5-0.70.70.20.3-0.60.20.60.60.5
Number of licking bursts0.40.71.6-1.3-0.7-0.4-1.01.0-0.7-0.8-0.8-0.7
Context. condit. distance diff. score0.81.05.52.4-1.3-0.7-0.00.2-0.4-0.7-0.7-0.6
Locomotion velocity, session 10.60.61.50.90.21.20.70.30.90.80.80.7
Locomotion distance, session 11.62.04.3-1.81.02.10.40.01.51.61.61.5
Locomotion velocity, session 22.93.45.10.01.62.02.0-1.41.92.32.32.1
Locomotion distance, session 22.02.84.7-2.01.72.20.7-0.41.71.91.91.7
Locomotion velocity, session 30.60.72.01.3-1.40.5-0.31.00.3-0.6-0.6-0.5
Locomotion distance, session 31.11.22.1-1.2-1.4-0.0-1.41.4-0.5-0.9-0.9-0.9
Stereotopy head waving bouts, day 30.20.21.11.10.2-0.00.6-0.20.10.00.00.3
Stereotopy head waving duration, day 30.80.95.92.40.30.01.3-0.60.30.10.10.2
Locomotion velocity, session 70.60.71.11.0-0.9-0.8-0.50.6-0.9-0.8-0.8-0.8
Locomotion distance, session 71.01.31.81.1-0.9-1.0-1.11.2-1.2-1.2-1.2-1.4
Stereotopy head waving bouts, day 70.91.04.32.1-0.10.71.4-0.80.70.70.70.8
Stereotopy head waving duration, day 71.31.53.31.80.40.91.8-1.41.10.90.91.0
Locomotion velocity, session 81.01.23.51.90.31.31.3-0.41.20.80.80.8
Locomotion distance, session 80.40.61.41.20.30.80.8-0.60.90.70.70.7
Degree of sensitization distance1.11.17.02.70.3-1.10.4-0.3-0.7-0.4-0.4-0.5
Degree of sensitization stereotypy1.61.83.21.80.31.41.8-1.11.41.21.21.2
Conditioned locomotion0.50.61.51.2-0.7-0.7-0.10.5-0.7-0.9-0.8-0.8
Cocaine response after cond. corrected0.70.81.50.91.00.81.2-0.80.80.90.90.9
Cocaine response after cond. not corrected0.91.01.70.41.10.81.3-1.10.91.11.11.1
Cocaine response before conditioning0.20.21.9-1.4-0.2-0.2-0.4-0.1-0.10.10.10.1
Saline control response0.10.20.60.6-0.80.1-0.20.60.10.30.30.3
Bone: connectivity density0.10.10.40.6-0.4-0.4-0.30.4-0.5-0.2-0.2-0.1
Bone: cortical apparent density2.12.94.9-0.5-2.2-1.7-2.01.9-1.9-1.6-1.6-1.5
Bone: cortical area0.10.10.40.10.40.00.6-0.2-0.10.40.40.4
Bone: cortical porosity1.21.32.10.51.30.91.4-1.11.11.21.21.2
Bone: cortical porosity2.02.13.51.11.41.41.9-1.21.51.51.51.5
Bone: cortical thickness0.20.43.1-1.80.3-0.1-0.30.1-0.3-0.1-0.10.0
Bone: cortical thickness0.40.53.8-2.00.70.3-0.0-0.10.10.20.20.3
Bone: cortical tissue density2.12.84.8-0.3-2.2-1.6-2.01.9-1.9-1.5-1.5-1.4
Condit. Reinf. active minus inactive responses1.11.32.3-0.7-1.3-0.9-1.51.5-1.1-0.9-0.9-1.0
Condit. Reinf. active-inactive response ratio0.91.02.3-0.1-1.5-0.7-1.31.5-0.9-0.7-0.7-0.8
Condit. Reinf. active responses2.12.64.3-1.0-1.5-1.6-2.11.6-1.6-1.7-1.7-1.7
Condit. Reinf. inactive responses2.02.43.9-0.8-1.0-1.7-1.80.8-1.4-2.0-2.0-1.9
Incentive salience index mean2.42.94.3-0.7-1.7-1.7-2.11.9-1.9-1.6-1.6-1.7
Condit. Reinf. lever presses3.24.56.0-0.8-1.9-2.4-2.31.9-2.5-2.2-2.3-2.3
Condit. Reinf. active minus inactive responses0.70.91.4-0.31.21.00.7-0.61.01.11.11.1
Condit. Reinf. active-inactive response ratio0.40.50.80.30.90.60.7-0.50.70.80.80.7
Condit. Reinf. active responses1.52.12.9-0.11.51.71.2-1.01.71.71.71.6
Condit. Reinf. inactive responses0.50.71.6-0.50.51.30.5-0.11.01.01.00.9
Condit. Reinf. lever presses0.10.10.5-0.70.60.1-0.1-0.40.20.40.30.3
Condit. Reinf. lever reinforcers received1.21.72.20.11.41.41.2-1.01.51.51.51.4
Conditioned reinforcement - actives0.61.13.2-1.81.01.50.2-0.31.00.80.80.8
Conditioned reinforcement - inactives0.50.75.2-2.30.60.0-0.80.3-0.2-0.2-0.2-0.2
Conditioned locomotion1.92.44.3-1.12.11.81.5-1.41.91.31.31.3
Patch foraging indifference point 0 sec0.91.72.50.5-1.4-1.2-1.41.6-1.3-1.4-1.4-1.4
Patch foraging indifference point AUC0.50.72.3-1.1-0.50.4-1.21.5-0.0-0.6-0.6-0.6
Delay disc. indifference point, 0s delay0.50.61.7-0.61.30.00.9-1.30.50.40.50.5
Delay disc. indifference point, 16s delay1.41.63.0-1.51.71.40.7-1.11.11.21.21.2
Delay disc. indifference point, 2s delay7.88.712.9-2.93.62.82.3-3.22.83.02.92.8
Delay disc. indifference point, 24s delay0.91.03.70.6-1.3-0.1-1.11.9-0.8-0.8-0.6-0.8
Delay disc. indifference point, 4s delay2.32.44.4-0.92.11.51.3-1.81.51.41.61.5
Delay disc. indifference point, 8s delay0.30.32.1-1.40.3-0.1-0.80.3-0.2-0.1-0.3-0.2
Indifference point function ln k0.30.52.51.6-0.2-0.30.8-0.7-0.10.40.40.4
Indifference point function log k0.30.52.51.6-0.2-0.30.8-0.7-0.10.40.40.4
Patch foraging total patch changes 0 sec0.71.42.00.0-1.2-1.1-1.41.4-1.1-1.2-1.2-1.2
Patch foraging total patch changes 12 sec0.20.21.3-0.0-0.40.4-0.41.1-0.0-0.0-0.0-0.0
Patch foraging total patch changes 18 sec0.60.92.5-0.4-0.7-0.4-1.11.6-0.8-1.0-1.0-1.0
Patch foraging total patch changes 24 sec1.32.33.8-1.3-1.3-1.0-1.91.9-1.2-1.5-1.6-1.5
Patch foraging total patch changes 6 sec0.40.71.3-0.5-0.6-0.3-1.01.2-0.5-1.0-1.0-1.0
Patch foraging time to switch 0 sec1.63.37.20.32.41.22.3-2.71.51.61.61.6
Patch foraging water rate 0 sec2.96.18.30.7-2.8-2.4-2.62.9-2.4-2.6-2.6-2.5
Patch foraging water rate 12 sec0.91.83.3-0.5-1.8-1.6-1.51.5-1.8-1.0-1.0-1.0
Patch foraging water rate 18 sec2.74.17.80.5-2.6-1.7-2.12.8-2.0-1.9-1.9-1.9
Patch foraging water rate 24 sec1.21.73.51.6-1.9-1.3-0.91.4-1.4-1.0-1.0-1.0
Patch foraging water rate 6 sec3.65.37.2-0.5-2.7-2.4-2.52.4-2.5-2.3-2.3-2.2
Seeking ratio, delayed vs. immediate footshock0.20.20.7-0.20.50.50.4-0.80.60.10.10.1
Distance traveled before self-admin1.52.04.6-0.72.11.21.4-1.81.31.21.21.2
Distance traveled after self-admin0.50.61.20.6-0.5-0.6-0.61.1-0.8-0.8-0.8-0.9
Extensor digitorum longus weight0.51.85.2-1.81.90.31.0-2.30.80.90.90.8
Bone: elastic displacement0.30.31.71.3-0.0-0.20.5-0.3-0.0-0.6-0.5-0.5
Bone: elastic work0.91.23.71.91.10.51.7-1.30.80.30.30.3
Bone: endosteal estimation0.51.23.81.90.50.81.4-0.40.81.11.10.9
Bone: endosteal perimeter0.61.23.31.80.40.71.6-0.60.61.21.21.1
Epididymis fat weight0.20.85.02.2-0.8-0.80.3-0.3-0.3-0.2-0.2-0.2
Delta time in closed arm before/after self-admin0.40.41.7-1.30.60.50.1-0.30.60.30.30.3
Delta time in open arm before/after self-admin0.10.10.20.50.40.40.4-0.40.40.10.20.2
Diff in mean of infusions in LGA sessions0.30.30.80.5-0.8-0.3-0.60.9-0.5-0.4-0.5-0.5
Delay discount exponential model param1.41.52.91.7-1.7-1.3-0.61.1-1.1-1.1-1.1-1.1
Extinction: sum of active levers before priming2.12.43.1-0.71.71.81.4-1.41.41.81.71.7
Active lever presses in extinction session 60.50.50.8-0.10.60.70.7-0.60.50.90.90.9
Bone: final force0.40.61.50.50.90.61.2-0.60.50.80.80.9
Bone: final moment0.40.61.40.80.90.51.2-0.50.40.80.80.9
Food consumed during 24 hour testing period0.30.50.7-0.20.60.80.7-0.30.70.90.90.8
Glucose1.01.53.0-0.4-0.7-1.7-1.10.7-1.5-1.4-1.4-1.4
Heart weight0.71.17.72.8-0.9-0.70.40.5-0.8-0.1-0.1-0.2
Delay discount hyperbolic model param2.22.44.31.9-2.1-1.5-0.91.5-1.4-1.4-1.5-1.4
Intermittent access intake day 1-15 change0.00.10.5-0.7-0.30.0-0.30.2-0.0-0.2-0.2-0.2
Intermittent access intake escalation0.10.20.5-0.7-0.5-0.1-0.50.4-0.2-0.3-0.3-0.3
Intermittent access intake escalation 20.50.60.8-0.5-0.8-0.7-0.90.8-0.7-0.8-0.8-0.8
Intermitt. access day 1 inactive lever presses0.31.01.51.2-0.5-1.0-0.71.1-1.1-1.0-1.0-1.0
Intermitt. access day 15 inactive lever presses0.20.40.60.1-0.2-0.6-0.70.8-0.7-0.7-0.7-0.7
Intermitt. access escalation Index0.20.32.5-1.6-0.10.1-0.4-0.0-0.00.20.20.2
Intermittent access day 1 total infusions1.82.96.0-1.11.92.41.3-1.01.81.71.71.7
Intermittent access day 15 total infusions0.91.32.8-1.51.11.70.5-0.51.21.11.11.1
Intermittent access terminal intake (last 3 days)1.01.33.3-1.11.11.80.6-0.51.31.21.21.2
Intermittent access total infusions2.52.95.6-1.52.12.41.2-1.11.81.61.61.6
Intermittent access day 1 locomotion0.40.61.3-1.11.10.90.3-0.40.60.60.60.6
Intermittent access day 15 total locomotion0.10.20.6-0.80.60.50.10.10.20.30.30.3
Intermittent access total locomotion0.10.10.5-0.70.4-0.0-0.20.4-0.1-0.2-0.2-0.2
Intermittent access standard deviation0.10.21.5-0.11.20.30.6-0.30.30.20.20.2
Left kidney weight1.25.629.45.40.41.33.0-1.31.51.41.41.5
Right kidney weight1.14.936.16.0-0.30.12.4-0.80.60.70.70.7
Cocaine induced anxiety0.20.21.00.30.50.10.7-1.00.50.10.10.1
Post-drug Anxiety0.60.71.90.7-0.5-1.4-0.2-0.3-0.9-0.9-0.9-0.9
Baseline Anxiety0.40.51.3-0.4-0.7-0.9-0.80.8-1.1-0.4-0.4-0.4
Tail length1.24.66.20.9-2.5-2.4-2.12.0-2.2-2.3-2.3-2.4
Length with tail0.83.56.62.6-2.4-1.9-1.11.6-1.7-1.7-1.7-1.8
Length without tail0.41.29.83.1-0.6-0.30.70.2-0.2-0.2-0.2-0.1
Times rat made contact with spout4.75.411.3-1.4-2.8-1.8-3.03.4-2.5-1.8-1.8-1.8
Lifetime Intake2.73.25.9-1.52.32.41.3-1.11.91.81.81.8
Liver weight, left0.10.10.40.2-0.30.50.20.00.60.10.10.1
Liver weight, right0.71.24.31.2-2.1-0.9-0.60.9-0.7-0.9-0.9-0.9
Locomotor activity0.20.20.90.9-0.5-0.00.40.1-0.10.50.50.6
Locomotor testing distance0.30.50.9-1.0-0.9-0.7-0.90.8-0.9-0.3-0.3-0.2
Locomotor testing rearing0.20.41.20.1-0.20.50.40.30.21.01.01.1
Locomotion in novel chamber0.50.62.8-1.7-0.5-0.6-0.8-0.1-0.4-0.6-0.6-0.6
Locomotion in novel chamber post-restriction0.50.85.5-2.40.60.6-0.0-0.60.60.40.50.4
Fecal boli incidents, locomotor time 10.50.82.40.1-0.7-0.5-0.91.6-1.0-0.9-0.8-0.8
Change in fecal boli incidents, locomotor task0.70.72.60.7-1.6-0.3-0.61.4-0.4-0.4-0.4-0.5
Time >=10cm from walls, locomotor time 10.20.21.51.20.20.20.6-0.30.20.00.10.1
Bouts of movement, locomotor time 10.10.10.40.1-0.6-0.2-0.30.5-0.3-0.2-0.0-0.2
Total resting periods, locomotor time 10.10.10.20.4-0.3-0.3-0.20.3-0.4-0.2-0.1-0.3
Rest time, locomotor task time 10.70.91.11.1-0.7-0.9-0.71.0-0.9-1.1-0.9-1.0
Distance moved, locomotor task time 10.10.20.40.3-0.10.50.5-0.40.60.50.40.6
Vertical activity count, locomotor time 11.12.63.90.1-1.6-1.9-1.51.3-1.7-1.9-2.0-1.7
Time >=10cm from walls, locomotor time 21.82.73.81.4-1.7-1.6-1.11.6-1.8-1.7-1.8-2.0
Bouts of movement, locomotor time 21.32.14.6-2.11.51.01.0-1.71.41.41.21.4
Total resting periods, locomotor time 21.73.05.0-2.21.91.41.3-1.91.71.61.51.7
Rest time, locomotor task time 20.00.00.1-0.10.3-0.1-0.10.2-0.1-0.2-0.1-0.1
Distance moved, locomotor task time 20.30.41.11.0-0.9-0.6-0.30.5-0.5-0.5-0.6-0.6
Vertical activity count, locomotor time 22.02.83.80.6-1.8-2.0-1.41.7-1.9-1.7-1.8-1.9
Light reinforcement 10.10.20.40.10.20.40.4-0.10.30.60.60.6
Light reinforcement 20.50.71.30.10.70.81.1-1.21.20.70.70.7
Bone: marrow area0.61.34.12.00.50.91.4-0.40.81.11.11.0
Bone: maximum diameter0.50.92.81.70.50.51.5-0.50.50.90.90.9
Bone: maximum force0.40.71.70.61.00.71.3-0.60.60.90.90.9
Bone: maximum moment0.50.91.80.81.00.71.3-0.60.61.01.01.0
Mean time between licks in bursts1.22.94.70.11.91.31.8-2.21.41.91.91.8
Mean num. licks in bursts0.40.71.80.3-1.3-0.7-1.01.4-0.8-0.4-0.4-0.4
Cd content in liver0.20.20.5-0.6-0.20.70.30.10.60.40.40.4
Co content in liver0.30.32.4-1.50.2-0.2-0.20.0-0.3-0.4-0.4-0.4
Cu content in liver1.11.34.4-2.1-0.5-0.8-1.40.9-1.1-0.9-1.0-1.0
Fe content in liver0.91.17.32.70.20.11.4-0.70.50.10.10.1
K content in liver0.10.10.3-0.0-0.4-0.3-0.50.5-0.4-0.00.0-0.0
Mg content in liver0.30.30.80.0-0.5-0.4-0.70.9-0.6-0.3-0.3-0.3
Mn content in liver0.10.10.6-0.8-0.00.4-0.20.20.30.00.00.0
Na content in liver0.60.71.10.2-0.6-1.0-0.80.7-1.0-0.9-0.8-0.9
Rb content in liver0.00.00.10.30.1-0.0-0.10.3-0.2-0.1-0.2-0.2
Se content in liver0.20.31.6-1.3-0.20.40.1-0.20.40.50.50.5
Sr content in liver1.21.05.3-2.3-0.0-0.7-1.20.0-0.7-0.7-0.7-0.7
Zn content in liver0.30.30.9-0.7-0.9-0.1-0.81.0-0.4-0.0-0.0-0.0
Bone: minimum diameter0.30.50.80.30.60.70.8-0.30.60.90.90.8
Time in familiar zone, hab. session 10.00.00.10.2-0.2-0.10.00.2-0.3-0.2-0.2-0.2
Time in novel zone, hab. session 10.20.20.60.80.10.30.6-0.40.60.30.30.2
Total zone transitions, hab. session 10.30.42.6-1.6-0.20.5-0.70.20.40.10.1-0.2
Total locomotion distance, hab. session 10.30.41.3-1.1-0.80.2-0.80.70.0-0.1-0.1-0.3
Locomotion velocity, hab. session 10.30.41.6-1.3-0.70.0-0.90.7-0.1-0.1-0.1-0.4
Time in familiar zone, hab. session 20.40.40.6-0.6-0.8-0.4-0.60.3-0.5-0.7-0.7-0.8
Time in novel zone, hab. session 20.30.30.6-0.10.80.50.4-0.20.60.70.70.8
Total zone transitions, hab. session 20.40.51.8-0.7-0.50.2-0.91.3-0.2-0.6-0.6-0.8
Total locomotion distance, hab. session 20.20.20.7-0.60.50.80.10.20.60.20.20.1
Locomotion velocity, hab. session 20.10.10.3-0.60.30.5-0.20.50.3-0.1-0.1-0.2
Novel to familiar place preference ratio0.20.30.91.0-0.50.40.4-0.00.60.40.40.3
Novelty place preference0.20.20.91.0-0.80.30.30.20.40.30.30.2
Time in novel zone, NPP test0.20.31.01.0-0.90.30.20.20.40.20.20.2
Total zone transitions, NPP test0.40.52.4-1.5-0.40.5-0.90.90.1-0.2-0.2-0.4
Total locomotion distance, NPP test0.10.10.6-0.3-0.00.8-0.20.50.50.20.20.1
Locomotion velocity, NPP test0.10.10.5-0.70.10.7-0.30.40.40.10.10.0
Intraocular pressure0.30.40.70.70.20.90.8-0.30.60.60.60.6
Delta distance traveled before/after self-admin4.04.38.41.6-2.7-1.5-1.82.9-1.8-1.9-1.9-1.9
Delta ambulatory time before/after self-admin2.53.17.61.7-2.5-1.0-1.52.8-1.5-1.4-1.4-1.5
Parametrial fat weight1.94.47.50.5-2.4-2.7-1.91.4-2.5-2.2-2.2-2.2
Pavlov. Cond. lever latency0.10.10.40.60.20.40.4-0.20.50.20.20.2
Pavlov. Cond. magazine entry latency0.50.61.5-1.21.20.50.5-0.90.50.70.60.5
Pavlov. Cond. change in total contacts0.50.62.7-1.60.80.7-0.0-0.10.40.60.60.6
Pavlov. Cond. index score0.10.10.7-0.90.3-0.1-0.10.0-0.20.20.10.1
Pavlov. Cond. latency score0.10.10.6-0.70.2-0.2-0.1-0.1-0.20.10.10.1
Pavlov. Cond. lever contacts0.40.40.9-0.9-0.2-0.8-0.80.4-0.9-0.5-0.6-0.5
Pavlov. Cond. magazine entry number0.20.31.91.4-0.6-0.30.10.1-0.1-0.4-0.3-0.2
Pavlov. Cond. intertrial magazine entries1.61.93.00.2-1.4-1.3-1.71.7-1.4-1.3-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.9-1.00.2-0.1-0.20.1-0.30.10.10.1
Pavlov. Cond. response bias0.20.21.5-1.20.4-0.2-0.30.0-0.40.0-0.0-0.1
Pavlov. Cond. lever latency0.20.30.6-0.60.00.80.30.10.60.60.60.7
Pavlov. Cond. magazine entry latency0.20.30.7-0.80.5-0.4-0.60.1-0.3-0.6-0.6-0.6
Pavlov. Cond. change in total contacts0.60.94.42.10.2-0.90.3-0.1-0.7-0.8-0.8-0.9
Pavlov. Cond. index score0.40.50.90.30.0-0.9-0.60.3-0.8-0.9-0.9-1.0
Pavlov. Cond. latency score0.60.71.20.3-0.1-1.1-0.80.5-1.0-1.1-1.1-1.1
Pavlov. Cond. lever contacts0.30.50.90.5-0.3-0.9-0.50.2-0.8-0.8-0.8-0.9
Pavlov. Cond. magazine entry number0.30.40.8-0.2-0.00.70.5-0.20.50.80.80.9
Pavlov. Cond. intertrial magazine entries0.30.41.00.1-0.6-0.5-0.71.0-0.7-0.5-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.30.2-0.8-0.4-0.0-0.6-0.8-0.8-0.8
Pavlov. Cond. response bias0.10.20.40.30.4-0.5-0.1-0.2-0.3-0.6-0.6-0.6
Time in closed arm before self-admin0.30.41.2-0.40.2-1.1-0.5-0.0-0.7-0.8-0.8-0.8
Time in closed arm after self-admin1.11.21.9-0.3-0.8-1.2-1.11.1-0.9-1.3-1.4-1.4
Time in open arm before self-admin0.50.51.20.3-1.1-0.6-0.81.1-0.8-0.5-0.4-0.4
Time in open arm after self-admin0.00.00.0-0.1-0.20.0-0.1-0.0-0.1-0.00.00.0
Bone: periosteal estimation0.51.02.01.40.60.71.4-0.50.71.11.11.0
Bone: periosteal perimeter0.40.83.31.8-0.00.41.3-0.00.20.80.80.7
Bone: post-yield work0.20.30.7-0.30.50.80.50.10.40.70.70.6
Progressive ratio test 1 active lever presses1.92.44.6-1.01.92.11.2-1.01.71.51.51.5
Progressive ratio test 1 breakpoint1.72.04.2-0.91.72.01.1-0.91.61.41.41.4
Progressive ratio test 1 inactive lever presses1.42.16.8-0.72.61.31.4-1.71.50.90.90.9
Progressive ratio test 2 active lever presses0.81.03.0-1.71.11.40.1-0.20.90.70.70.7
Progressive ratio test 2 breakpoint1.11.33.2-1.81.31.60.4-0.41.20.90.90.9
Progressive ratio test 2 inactive lever presses0.40.74.7-2.20.50.6-0.70.30.30.00.00.0
Incentive Sensitization - Responses0.20.21.6-1.3-0.00.2-0.60.3-0.0-0.1-0.1-0.1
Incentive Sensitization - Breakpoint0.20.21.5-1.20.10.3-0.50.20.1-0.1-0.1-0.1
Sum of active levers in priming session hrs 5-60.10.10.30.00.3-0.20.3-0.6-0.00.10.00.0
Progressive ratio0.20.30.60.50.80.50.6-0.70.70.20.40.4
Food seeking constrained by brief footshock0.81.01.6-0.90.81.10.9-0.50.91.31.21.3
Seeking ratio, punishment vs. effort0.10.10.5-0.7-0.1-0.00.00.3-0.20.30.10.1
Retroperitoneal fat weight0.31.27.22.7-0.5-1.01.1-0.8-0.6-0.0-0.00.1
Reaction time number correct0.20.41.2-1.1-0.80.5-0.60.70.1-0.2-0.2-0.2
Reaction time mean minus median0.00.10.20.30.40.10.3-0.40.5-0.1-0.1-0.1
Reaction time mean minus median AUC0.00.10.30.60.1-0.20.2-0.30.2-0.4-0.4-0.4
Reaction time num false alarms0.00.10.2-0.3-0.4-0.0-0.20.3-0.10.30.30.3
Reaction time num false alarms AUC0.10.10.3-0.3-0.40.2-0.20.30.00.50.50.6
Reaction time trials correct on left0.20.41.2-1.1-0.80.5-0.60.70.1-0.2-0.2-0.2
Reaction time trials on left0.20.41.5-1.2-0.70.6-0.60.70.2-0.1-0.1-0.1
Reaction time mean0.20.21.21.10.2-0.60.2-0.4-0.2-0.3-0.3-0.4
Reaction time mean AUC0.10.10.70.80.2-0.40.2-0.3-0.1-0.2-0.3-0.3
Median of all reaction times0.20.21.31.10.3-0.50.3-0.5-0.3-0.2-0.2-0.2
Reaction time omissions2.43.54.9-1.82.22.01.6-2.12.11.71.71.7
Reaction time false alarm rate0.10.10.30.20.1-0.20.2-0.2-0.00.50.50.6
Reaction time premature initiation rate0.00.10.20.10.50.00.3-0.10.00.30.30.3
Reaction time premature initiations0.00.00.1-0.2-0.00.2-0.10.40.0-0.0-0.0-0.0
Std. dev. reaction times0.10.10.60.8-0.0-0.30.1-0.20.1-0.4-0.4-0.5
Reaction time trials completed0.20.41.5-1.2-0.70.6-0.60.70.2-0.1-0.1-0.1
Reaction time trials AUC0.20.31.0-1.0-0.70.6-0.50.60.3-0.1-0.1-0.0
Run reversals in cocaine runway, females1.01.01.40.8-1.2-1.0-0.80.7-0.9-1.1-1.2-1.2
Run reversals in cocaine runway, males0.60.61.71.0-0.41.30.00.70.90.90.70.6
Latency to leave start box in cocaine runway2.32.74.21.21.61.42.0-2.01.51.51.71.6
Latency to leave start box in cocaine runway, F1.61.93.20.91.51.11.8-1.61.01.41.51.3
Latency to leave start box in cocaine runway, M0.70.61.10.90.60.60.9-1.00.90.40.70.8
Std. dev. time between licks in bursts0.00.10.40.60.10.00.00.0-0.10.20.20.2
Total sessions with >9 infusions1.92.34.10.11.82.01.6-1.11.61.61.61.6
Short access day 1 total inactive lever presses0.40.53.31.80.70.30.40.20.4-0.2-0.2-0.2
Short access day 10 total inactive lever presses2.35.58.21.6-2.6-2.4-2.22.9-2.4-2.2-2.2-2.2
Short access day 1 total infusions0.10.10.30.60.40.40.10.30.10.10.10.1
Short access day 10 total infusions1.82.34.5-0.11.72.11.5-1.01.61.61.61.6
Short access total infusions1.92.54.6-0.31.92.11.4-1.01.71.61.61.6
Short access day 1 locomotion0.10.10.50.70.20.20.00.40.1-0.2-0.2-0.2
Short access day 10 total locomotion0.81.52.4-0.4-0.3-1.6-1.21.1-1.5-1.4-1.4-1.4
Short access total locomotion0.10.10.7-0.10.80.10.2-0.20.2-0.1-0.1-0.1
One hour access (0.3 mA shock)2.02.38.3-2.91.42.00.2-0.51.21.31.31.3
Compulsive drug intake1.01.22.2-0.8-1.0-0.9-1.51.1-1.0-1.1-1.1-1.1
One hour access (shock baseline)1.72.64.0-1.41.92.01.3-1.41.71.61.61.6
Social response proportion5.05.710.40.93.01.93.1-3.22.42.02.02.0
Social responses1.11.41.9-0.21.41.31.2-1.11.11.31.31.3
Social time0.40.62.5-1.61.20.50.2-0.50.20.50.50.5
Soleus weight1.95.67.9-1.4-1.8-2.7-2.72.2-2.8-2.4-2.4-2.4
Bone: stiffness0.10.20.90.90.4-0.30.7-0.2-0.3-0.0-0.1-0.1
Tibialis anterior weight0.51.811.2-3.41.70.3-0.1-1.30.60.30.30.3
Time to tail flick, vehicle, before self-admin0.30.30.7-0.30.70.50.6-0.80.70.40.40.4
Time to tail flick, vehicle, after self-admin1.92.53.80.8-1.7-1.6-1.51.6-1.3-1.9-1.8-1.8
Time to tail flick, test, before self-admin0.50.61.8-1.30.50.90.2-0.60.90.60.60.6
Time to tail flick, test, after self-admin1.01.01.70.1-1.1-0.9-1.11.1-1.0-1.3-1.0-1.0
Delta time to tail flick, vehicle, before/after SA0.20.20.90.9-0.3-0.2-0.20.5-0.2-0.4-0.3-0.3
Delta time to tail flick, test, before/after SA1.71.72.5-0.1-1.2-1.6-1.31.0-1.5-1.6-1.4-1.4
Tibia length0.10.20.91.00.20.20.7-0.10.00.30.30.4
Ambulatory time before self-admin0.50.71.9-0.81.40.60.6-1.10.70.60.60.6
Ambulatory time after self-admin0.81.02.50.3-1.1-0.7-1.11.6-1.1-0.7-0.9-0.9
Bone: tissue strength0.10.10.40.70.1-0.20.4-0.30.0-0.2-0.2-0.3
Total heroin consumption1.61.82.7-1.41.21.60.8-0.81.21.61.61.6
Bone: trabecular number0.10.10.20.3-0.5-0.3-0.20.1-0.4-0.2-0.2-0.2
Bone: trabecular spacing0.30.40.80.6-0.2-0.3-0.00.8-0.5-0.8-0.9-0.9
Bone: trabecular thickness0.20.20.5-0.3-0.4-0.7-0.60.1-0.6-0.3-0.3-0.3
Bone: trabecular tissue density1.01.52.7-0.0-0.9-1.6-1.10.6-1.4-1.3-1.4-1.5
Water consumed over 24 hours1.11.53.8-0.7-1.4-0.9-1.72.0-1.2-0.8-0.8-0.8
Number of responses in last shaping day2.83.06.5-1.42.61.91.4-1.71.91.51.51.5