Hub : Genes

C6h14orf180

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039113395.2 0.14 0.11 8.8e-03 0.01 0.01 0 0.01 1.9e-02 4.8e-02 1.1e-01 3.2e-02
2 Adipose alternative TSS XM_039113395.2 0.04 0.03 1.9e-04 0.04 0.03 0.04 0.03 6.5e-05 6.2e-04 6.8e-05 1.2e-04
3 Liver gene expression C6h14orf180 0.02 0.02 4.7e-03 0.01 0 0.01 0.01 2.6e-02 8.6e-02 2.3e-02 5.8e-02
4 Adipose intron excision ratio chr6_137379035_137381179 0.03 0.02 8.5e-04 0.01 0.02 0.02 0.01 9.2e-03 3.0e-03 6.3e-03 1.4e-02
5 Adipose intron excision ratio chr6_137379035_137385300 0.03 0.02 1.7e-04 0.01 0.02 0.01 0.01 9.5e-03 3.0e-03 1.1e-02 1.6e-02
6 Adipose intron excision ratio chr6_137386369_137387229 0.54 0.14 0.0e+00 0.5 0.53 0.52 0.52 1.8e-63 1.5e-68 3.5e-68 4.0e-68
7 Adipose mRNA stability C6h14orf180 0.43 0.14 0.0e+00 0.39 0.39 0.39 0.39 2.8e-45 1.4e-45 1.3e-45 4.6e-46
8 Adipose intron excision ratio chr6_137385428_137386312 0.66 0.11 0.0e+00 0.57 0.58 0.58 0.58 2.5e-76 4.0e-78 5.2e-79 2.6e-78
9 Adipose gene expression C6h14orf180 0.3 0.16 0.0e+00 0.15 0.16 0.15 0.16 1.3e-16 4.4e-17 9.9e-17 3.0e-17
10 Adipose intron excision ratio chr6_137385428_137387123 0.5 0.13 0.0e+00 0.49 0.48 0.48 0.48 2.3e-61 4.0e-60 3.3e-60 5.6e-60
11 Adipose intron excision ratio chr6_137385428_137387229 0.65 0.12 0.0e+00 0.57 0.56 0.57 0.56 9.2e-77 3.2e-75 2.4e-76 7.8e-76
12 Adipose intron excision ratio chr6_137386369_137387123 0.58 0.12 0.0e+00 0.52 0.52 0.52 0.52 1.1e-67 1.6e-66 1.2e-67 4.5e-67

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.10.50.70.6-0.50.1-0.00.0-0.10.0-0.50.10.1-0.1
Area under the delay curve0.40.51.6-1.3-1.10.80.6-0.60.6-0.50.4-0.4-0.3-0.30.3
BMI with tail3.110.712.9-3.1-3.13.33.6-3.53.5-3.23.1-3.5-3.1-3.13.1
BMI without tail1.95.77.5-2.4-2.32.52.7-2.62.6-2.32.1-2.6-2.1-2.12.1
Body weight0.62.75.22.32.2-2.0-1.31.5-1.51.4-1.51.11.41.4-1.4
Weight adjusted by age0.30.40.50.50.6-0.5-0.60.6-0.60.7-0.70.60.70.7-0.7
Bone surface0.00.10.2-0.3-0.50.30.3-0.30.3-0.20.2-0.4-0.0-0.00.0
Bone volume0.00.10.1-0.2-0.40.20.3-0.20.2-0.1-0.0-0.40.20.2-0.2
Breakpoint value in progressive ratio session0.10.20.50.70.7-0.6-0.00.0-0.0-0.30.2-0.3-0.3-0.30.3
Number of licking bursts0.30.41.6-1.2-1.31.00.4-0.50.5-0.30.3-0.3-0.4-0.40.4
Context. condit. distance diff. score3.34.04.72.01.9-1.7-2.12.1-2.11.9-2.02.22.02.0-2.0
Locomotion velocity, session 10.10.20.30.50.5-0.4-0.40.4-0.40.3-0.30.50.30.3-0.3
Locomotion distance, session 10.50.71.0-0.1-0.20.40.8-0.80.8-1.01.0-1.0-0.9-0.90.9
Locomotion velocity, session 20.10.10.5-0.5-0.50.70.1-0.10.20.00.10.1-0.0-0.00.0
Locomotion distance, session 20.40.61.1-1.1-1.01.10.7-0.70.7-0.60.6-0.6-0.5-0.50.5
Locomotion velocity, session 30.10.10.1-0.00.00.20.3-0.20.2-0.40.4-0.4-0.3-0.30.3
Locomotion distance, session 30.00.00.1-0.2-0.20.3-0.00.0-0.0-0.00.00.00.00.0-0.0
Stereotopy head waving bouts, day 30.10.10.10.10.2-0.2-0.20.2-0.20.3-0.30.00.30.3-0.3
Stereotopy head waving duration, day 30.20.30.40.20.3-0.4-0.50.4-0.40.6-0.60.30.60.6-0.6
Locomotion velocity, session 70.20.20.40.20.20.00.4-0.40.4-0.60.6-0.5-0.6-0.60.6
Locomotion distance, session 70.81.11.6-1.1-1.11.31.0-1.01.0-1.01.0-0.9-1.1-1.11.1
Stereotopy head waving bouts, day 71.71.93.81.82.0-1.9-1.21.3-1.31.1-1.10.91.21.2-1.2
Stereotopy head waving duration, day 71.01.22.81.61.7-1.6-0.90.9-0.90.8-0.80.60.80.8-0.8
Locomotion velocity, session 81.31.52.71.61.6-1.3-1.11.2-1.21.0-1.11.11.11.1-1.1
Locomotion distance, session 80.20.30.60.70.7-0.4-0.50.6-0.60.4-0.50.60.50.5-0.5
Degree of sensitization distance0.30.30.4-0.4-0.40.40.5-0.50.5-0.50.5-0.4-0.7-0.70.7
Degree of sensitization stereotypy0.70.71.71.21.3-1.3-0.70.7-0.70.6-0.60.50.70.7-0.7
Conditioned locomotion1.51.72.11.41.4-1.4-1.31.3-1.31.3-1.31.21.21.2-1.2
Cocaine response after cond. corrected0.60.71.40.30.3-0.00.8-0.80.8-0.90.9-1.2-1.1-1.11.1
Cocaine response after cond. not corrected1.61.93.3-0.5-0.50.81.5-1.51.5-1.51.5-1.8-1.6-1.61.6
Cocaine response before conditioning2.32.75.0-2.2-2.22.21.7-1.61.6-1.51.4-1.4-1.2-1.21.2
Saline control response0.10.10.30.50.4-0.3-0.10.2-0.30.2-0.30.10.40.4-0.4
Bone: connectivity density0.40.61.31.11.0-1.0-0.60.7-0.70.4-0.50.50.70.7-0.7
Bone: cortical apparent density6.08.29.82.12.1-2.5-3.13.0-3.03.1-3.13.03.03.0-3.0
Bone: cortical area0.20.30.40.60.6-0.6-0.50.5-0.50.6-0.50.30.40.4-0.4
Bone: cortical porosity0.70.71.10.60.8-0.6-0.70.8-0.80.8-0.90.71.01.0-1.0
Bone: cortical porosity0.10.10.20.30.4-0.2-0.10.2-0.20.1-0.20.10.30.3-0.3
Bone: cortical thickness0.50.82.21.51.5-1.4-0.70.7-0.70.7-0.60.30.50.5-0.5
Bone: cortical thickness1.01.21.80.90.9-0.9-1.01.0-1.11.3-1.30.91.31.3-1.3
Bone: cortical tissue density5.98.09.72.12.1-2.5-3.13.0-3.03.1-3.03.03.03.0-3.0
Condit. Reinf. active minus inactive responses0.50.61.2-0.2-0.20.30.8-0.80.8-0.80.8-1.1-0.9-0.90.9
Condit. Reinf. active-inactive response ratio2.52.73.4-1.1-1.11.21.8-1.71.7-1.81.8-1.8-1.8-1.81.8
Condit. Reinf. active responses0.20.20.50.50.5-0.30.3-0.30.3-0.30.3-0.7-0.4-0.40.4
Condit. Reinf. inactive responses1.82.23.51.91.9-1.7-1.51.5-1.51.4-1.41.11.31.3-1.3
Incentive salience index mean0.40.51.20.30.3-0.10.7-0.70.7-0.80.8-1.1-0.9-0.90.9
Condit. Reinf. lever presses0.20.20.40.60.6-0.30.3-0.30.3-0.50.5-0.6-0.5-0.50.5
Condit. Reinf. active minus inactive responses0.70.91.20.60.5-0.5-0.91.0-1.00.9-1.11.11.11.1-1.1
Condit. Reinf. active-inactive response ratio0.60.71.00.30.3-0.4-0.80.8-0.80.9-1.01.01.01.0-1.0
Condit. Reinf. active responses0.10.10.2-0.2-0.30.3-0.10.1-0.20.3-0.40.20.50.5-0.5
Condit. Reinf. inactive responses0.40.50.8-0.7-0.80.90.9-0.80.8-0.70.6-0.9-0.6-0.60.6
Condit. Reinf. lever presses1.41.94.0-1.9-2.02.01.4-1.31.3-1.11.1-0.9-0.9-0.90.9
Condit. Reinf. lever reinforcers received0.10.20.3-0.1-0.20.2-0.20.3-0.30.4-0.50.40.60.6-0.6
Conditioned reinforcement - actives0.30.50.80.30.3-0.4-0.70.7-0.70.8-0.90.90.70.7-0.7
Conditioned reinforcement - inactives0.30.40.80.80.9-0.8-0.60.6-0.60.5-0.60.50.50.5-0.5
Conditioned locomotion0.10.10.20.20.3-0.00.4-0.30.3-0.40.3-0.3-0.4-0.40.4
Patch foraging indifference point 0 sec4.78.813.53.73.6-3.5-2.92.9-2.92.7-2.72.42.62.6-2.6
Patch foraging indifference point AUC2.23.17.92.82.8-2.6-1.71.6-1.61.1-1.21.11.01.0-1.0
Delay disc. indifference point, 0s delay0.30.30.50.50.5-0.7-0.50.5-0.50.5-0.60.40.60.6-0.6
Delay disc. indifference point, 16s delay0.60.61.8-1.3-1.21.10.7-0.70.7-0.50.5-0.4-0.5-0.50.5
Delay disc. indifference point, 2s delay1.41.64.8-2.2-2.11.71.0-1.11.1-0.80.8-0.8-0.7-0.70.7
Delay disc. indifference point, 24s delay0.60.61.2-1.1-1.10.90.8-0.80.8-0.70.6-0.7-0.6-0.60.6
Delay disc. indifference point, 4s delay0.30.30.6-0.8-0.70.3-0.30.2-0.20.4-0.50.60.60.6-0.6
Delay disc. indifference point, 8s delay0.20.20.8-0.9-0.70.40.4-0.40.4-0.50.4-0.3-0.3-0.30.3
Indifference point function ln k0.81.52.20.40.4-0.5-1.21.2-1.21.4-1.41.41.51.5-1.5
Indifference point function log k0.81.52.20.40.4-0.5-1.21.2-1.21.4-1.41.41.51.5-1.5
Patch foraging total patch changes 0 sec5.310.015.23.93.9-3.7-3.13.1-3.12.9-2.92.62.82.8-2.8
Patch foraging total patch changes 12 sec4.05.17.32.62.6-2.7-2.32.3-2.32.1-2.12.02.02.0-2.0
Patch foraging total patch changes 18 sec1.52.24.32.12.0-2.0-1.41.4-1.41.2-1.30.81.31.3-1.3
Patch foraging total patch changes 24 sec0.50.82.11.51.4-1.3-0.70.7-0.80.6-0.60.30.60.6-0.6
Patch foraging total patch changes 6 sec3.35.011.43.43.3-3.2-2.12.0-2.01.7-1.71.41.51.5-1.5
Patch foraging time to switch 0 sec7.615.618.3-4.2-4.34.14.2-4.14.1-3.93.9-3.8-3.6-3.63.6
Patch foraging water rate 0 sec13.327.931.55.35.3-5.3-5.65.5-5.55.3-5.35.15.15.1-5.1
Patch foraging water rate 12 sec6.814.217.72.72.7-2.8-4.03.9-3.94.2-4.24.14.14.1-4.1
Patch foraging water rate 18 sec4.16.37.51.81.8-1.9-2.72.7-2.72.7-2.72.72.72.7-2.7
Patch foraging water rate 24 sec3.95.47.21.41.3-1.4-2.42.4-2.42.7-2.62.52.72.7-2.7
Patch foraging water rate 6 sec4.46.47.42.12.2-2.2-2.72.7-2.72.7-2.72.62.62.6-2.6
Seeking ratio, delayed vs. immediate footshock0.30.30.60.40.3-0.2-0.60.6-0.60.7-0.70.40.70.7-0.7
Distance traveled before self-admin0.50.60.9-0.8-0.90.90.8-0.80.8-0.70.6-0.7-0.7-0.70.7
Distance traveled after self-admin0.30.30.50.10.3-0.4-0.50.6-0.60.6-0.70.60.70.7-0.7
Extensor digitorum longus weight7.730.236.96.16.0-6.0-5.65.7-5.75.2-5.35.25.05.0-5.0
Bone: elastic displacement0.30.40.80.00.0-0.1-0.60.5-0.50.7-0.80.50.90.9-0.9
Bone: elastic work0.10.20.6-0.8-0.80.6-0.10.0-0.00.3-0.30.20.30.3-0.3
Bone: endosteal estimation0.51.14.2-1.9-2.01.80.8-0.80.8-0.40.4-0.2-0.3-0.30.3
Bone: endosteal perimeter0.10.20.7-0.7-0.80.70.5-0.40.4-0.20.3-0.2-0.4-0.40.4
Epididymis fat weight2.89.511.7-2.5-2.72.73.3-3.33.3-3.23.1-3.4-3.1-3.13.1
Delta time in closed arm before/after self-admin0.10.10.1-0.2-0.30.4-0.10.2-0.20.2-0.30.30.20.2-0.2
Delta time in open arm before/after self-admin0.60.61.71.01.2-1.3-0.70.7-0.70.4-0.50.40.40.4-0.4
Diff in mean of infusions in LGA sessions0.20.20.90.90.8-0.7-0.10.1-0.1-0.20.1-0.2-0.2-0.20.2
Delay discount exponential model param0.40.41.51.21.0-0.7-0.50.6-0.60.5-0.40.30.30.3-0.3
Extinction: sum of active levers before priming0.50.61.00.40.4-0.40.6-0.70.7-0.90.9-0.8-1.0-1.01.0
Active lever presses in extinction session 61.91.92.41.31.3-1.4-1.41.4-1.41.3-1.31.51.31.3-1.3
Bone: final force0.10.20.4-0.6-0.60.5-0.20.2-0.20.5-0.40.50.40.4-0.4
Bone: final moment0.10.20.3-0.4-0.40.3-0.30.3-0.30.5-0.50.50.50.5-0.5
Food consumed during 24 hour testing period0.40.60.80.80.7-0.9-0.70.8-0.80.7-0.70.50.80.8-0.8
Glucose0.30.50.90.30.4-0.5-0.70.6-0.60.9-0.90.30.90.9-0.9
Heart weight0.50.81.00.50.6-0.7-0.90.9-0.90.9-1.01.01.01.0-1.0
Delay discount hyperbolic model param0.40.41.61.31.1-0.8-0.50.6-0.60.5-0.40.30.30.3-0.3
Intermittent access intake day 1-15 change1.73.43.8-1.6-1.51.81.9-1.91.9-1.91.9-1.8-1.9-1.91.9
Intermittent access intake escalation1.73.43.9-1.6-1.41.71.9-2.01.9-1.91.9-1.8-2.0-2.02.0
Intermittent access intake escalation 21.31.42.0-0.7-0.60.81.2-1.31.3-1.31.3-1.2-1.4-1.41.4
Intermitt. access day 1 inactive lever presses0.20.91.71.21.3-1.2-0.90.9-0.90.7-0.70.90.70.7-0.7
Intermitt. access day 15 inactive lever presses1.42.84.51.92.0-2.1-1.61.7-1.71.5-1.61.41.51.5-1.5
Intermitt. access escalation Index0.81.11.60.70.7-0.5-1.01.1-1.11.1-1.11.11.31.3-1.3
Intermittent access day 1 total infusions0.20.30.4-0.3-0.30.30.6-0.60.5-0.60.5-0.6-0.6-0.60.6
Intermittent access day 15 total infusions1.32.02.2-1.3-1.11.41.5-1.51.5-1.41.3-1.4-1.5-1.51.5
Intermittent access terminal intake (last 3 days)1.82.42.7-1.4-1.21.31.6-1.61.6-1.61.5-1.6-1.6-1.61.6
Intermittent access total infusions0.60.70.9-0.8-0.70.80.9-0.90.9-0.90.8-0.9-0.9-0.90.9
Intermittent access day 1 locomotion1.11.51.9-0.7-0.60.91.3-1.31.3-1.41.3-1.3-1.4-1.41.4
Intermittent access day 15 total locomotion0.40.71.4-1.2-1.11.20.8-0.80.8-0.70.7-0.6-0.8-0.80.8
Intermittent access total locomotion0.60.71.0-0.5-0.30.50.9-0.90.9-1.00.8-1.0-1.0-1.01.0
Intermittent access standard deviation1.12.23.3-0.4-0.20.71.6-1.61.5-1.71.6-1.8-1.8-1.81.8
Left kidney weight2.09.110.03.13.0-3.0-2.93.0-3.12.9-3.02.83.23.2-3.2
Right kidney weight1.56.98.02.52.4-2.4-2.62.7-2.72.6-2.62.62.82.8-2.8
Cocaine induced anxiety1.11.62.70.91.0-1.1-1.51.4-1.41.4-1.21.61.11.1-1.1
Post-drug Anxiety2.72.94.41.21.2-1.5-1.91.8-1.81.8-1.72.11.61.6-1.6
Baseline Anxiety0.10.10.2-0.5-0.50.30.2-0.20.2-0.20.2-0.2-0.1-0.10.1
Tail length5.019.422.34.64.5-4.7-4.44.5-4.54.3-4.44.14.24.2-4.2
Length with tail8.034.643.96.66.5-6.5-5.96.0-6.05.5-5.65.45.45.4-5.4
Length without tail4.213.519.74.44.3-4.3-3.73.7-3.73.3-3.23.43.23.2-3.2
Times rat made contact with spout0.20.20.80.70.7-0.9-0.40.3-0.30.3-0.20.20.10.1-0.1
Lifetime Intake0.40.50.7-0.9-0.70.80.8-0.80.7-0.60.6-0.6-0.7-0.70.7
Liver weight, left2.84.65.92.32.3-2.4-2.22.2-2.22.1-2.11.92.02.0-2.0
Liver weight, right0.10.10.30.20.1-0.00.4-0.30.3-0.50.5-0.5-0.5-0.50.5
Locomotor activity0.20.30.40.20.1-0.1-0.60.6-0.60.6-0.50.60.60.6-0.6
Locomotor testing distance0.20.40.60.20.1-0.2-0.70.6-0.60.7-0.60.70.70.7-0.7
Locomotor testing rearing1.73.54.3-1.9-2.02.11.8-1.81.8-1.92.0-1.6-1.8-1.81.8
Locomotion in novel chamber3.44.45.71.41.4-1.7-2.12.1-2.22.3-2.32.42.32.3-2.3
Locomotion in novel chamber post-restriction0.00.10.3-0.5-0.50.50.2-0.10.1-0.10.00.0-0.1-0.10.1
Fecal boli incidents, locomotor time 11.42.03.0-0.6-0.50.51.5-1.41.4-1.71.6-1.5-1.7-1.71.7
Change in fecal boli incidents, locomotor task1.61.62.60.60.6-0.4-1.21.3-1.31.6-1.51.41.51.5-1.5
Time >=10cm from walls, locomotor time 10.50.52.41.61.5-0.90.00.1-0.1-0.20.3-0.3-0.3-0.30.3
Bouts of movement, locomotor time 11.61.93.0-1.0-0.80.71.4-1.41.4-1.61.5-1.7-1.4-1.41.4
Total resting periods, locomotor time 11.71.93.0-1.2-0.90.91.4-1.41.4-1.61.5-1.7-1.4-1.41.4
Rest time, locomotor task time 10.20.20.7-0.9-0.80.50.2-0.30.3-0.30.3-0.4-0.3-0.30.3
Distance moved, locomotor task time 10.10.20.8-0.8-0.80.90.4-0.40.4-0.00.20.0-0.1-0.10.1
Vertical activity count, locomotor time 10.10.40.6-0.2-0.20.1-0.60.5-0.50.7-0.60.70.80.8-0.8
Time >=10cm from walls, locomotor time 20.60.92.81.51.7-1.7-0.80.8-0.80.4-0.40.40.40.4-0.4
Bouts of movement, locomotor time 20.71.21.7-0.1-0.0-0.4-1.11.1-1.11.2-1.31.31.31.3-1.3
Total resting periods, locomotor time 20.50.91.3-0.3-0.2-0.2-1.00.9-0.91.1-1.11.11.11.1-1.1
Rest time, locomotor task time 20.10.10.2-0.3-0.30.0-0.20.2-0.20.4-0.40.30.30.3-0.3
Distance moved, locomotor task time 20.20.30.3-0.6-0.50.60.5-0.50.5-0.50.6-0.4-0.4-0.40.4
Vertical activity count, locomotor time 20.10.10.30.40.3-0.4-0.50.5-0.40.3-0.20.40.30.3-0.3
Light reinforcement 10.00.00.1-0.0-0.00.1-0.10.1-0.20.2-0.20.10.20.2-0.2
Light reinforcement 21.62.53.0-1.2-1.31.61.6-1.61.6-1.61.7-1.5-1.7-1.71.7
Bone: marrow area0.51.03.9-1.8-2.01.70.8-0.70.7-0.40.4-0.1-0.2-0.20.2
Bone: maximum diameter0.20.30.6-0.5-0.60.50.6-0.60.6-0.40.5-0.8-0.6-0.60.6
Bone: maximum force0.00.00.1-0.2-0.20.1-0.10.2-0.20.3-0.20.30.30.3-0.3
Bone: maximum moment0.00.00.10.00.0-0.1-0.10.2-0.20.3-0.30.20.30.3-0.3
Mean time between licks in bursts0.20.61.5-0.9-1.01.20.8-0.80.8-0.50.6-0.6-0.6-0.60.6
Mean num. licks in bursts0.50.72.41.51.6-1.4-0.60.6-0.60.4-0.50.30.40.4-0.4
Cd content in liver0.20.20.3-0.2-0.20.2-0.30.3-0.30.4-0.50.50.60.6-0.6
Co content in liver1.21.42.01.00.9-1.2-1.31.3-1.31.1-1.21.41.11.1-1.1
Cu content in liver1.41.61.9-1.3-1.31.41.3-1.31.3-1.11.3-1.2-1.3-1.31.3
Fe content in liver0.40.51.2-0.8-0.91.10.7-0.70.7-0.60.7-0.5-0.6-0.60.6
K content in liver0.40.40.60.80.7-0.8-0.70.6-0.60.7-0.60.60.50.5-0.5
Mg content in liver0.30.30.60.20.2-0.3-0.50.5-0.50.8-0.60.60.60.6-0.6
Mn content in liver0.00.00.1-0.3-0.20.20.10.0-0.00.1-0.10.20.20.2-0.2
Na content in liver0.60.71.0-0.5-0.50.60.8-0.80.9-0.70.9-1.0-1.0-1.01.0
Rb content in liver0.81.01.40.70.6-0.6-1.11.1-1.01.1-1.01.21.11.1-1.1
Se content in liver0.10.10.1-0.3-0.30.40.4-0.30.3-0.10.2-0.3-0.2-0.20.2
Sr content in liver0.20.10.2-0.4-0.40.2-0.30.3-0.30.4-0.40.50.40.4-0.4
Zn content in liver0.80.81.40.40.4-0.6-0.90.9-0.91.2-1.11.01.11.1-1.1
Bone: minimum diameter0.61.21.50.80.8-0.9-1.11.1-1.11.2-1.21.21.21.2-1.2
Time in familiar zone, hab. session 10.00.00.10.20.1-0.10.1-0.10.1-0.30.20.0-0.1-0.10.1
Time in novel zone, hab. session 10.50.51.5-1.1-1.11.20.7-0.70.6-0.40.4-0.7-0.4-0.40.4
Total zone transitions, hab. session 10.20.31.0-1.0-0.80.90.6-0.50.5-0.40.4-0.3-0.2-0.20.2
Total locomotion distance, hab. session 10.40.61.0-0.10.1-0.0-0.60.7-0.70.9-0.91.01.01.0-1.0
Locomotion velocity, hab. session 10.91.21.70.60.8-0.7-1.11.1-1.11.2-1.21.31.31.3-1.3
Time in familiar zone, hab. session 20.30.30.60.80.8-0.60.2-0.10.1-0.50.5-0.2-0.6-0.60.6
Time in novel zone, hab. session 20.30.31.1-1.0-1.00.90.5-0.50.5-0.10.1-0.40.10.1-0.1
Total zone transitions, hab. session 20.50.60.9-0.1-0.10.20.9-0.80.8-0.90.8-0.9-0.9-0.90.9
Total locomotion distance, hab. session 20.40.60.80.70.8-0.7-0.70.7-0.70.8-0.90.70.80.8-0.8
Locomotion velocity, hab. session 20.60.81.00.80.9-0.9-0.80.8-0.91.0-1.00.80.90.9-0.9
Novel to familiar place preference ratio0.60.70.9-0.5-0.60.80.8-0.90.8-0.90.8-0.9-0.8-0.80.8
Novelty place preference0.40.50.7-0.6-0.70.90.7-0.70.7-0.70.6-0.7-0.6-0.60.6
Time in novel zone, NPP test0.20.20.4-0.2-0.30.50.5-0.50.5-0.60.5-0.6-0.5-0.50.5
Total zone transitions, NPP test0.30.41.41.21.2-0.8-0.30.5-0.50.2-0.30.30.40.4-0.4
Total locomotion distance, NPP test0.40.51.00.91.0-0.7-0.60.7-0.70.5-0.70.70.70.7-0.7
Locomotion velocity, NPP test0.30.40.50.70.7-0.5-0.50.6-0.60.6-0.70.60.70.7-0.7
Intraocular pressure0.00.00.1-0.4-0.30.30.1-0.10.1-0.20.0-0.00.10.1-0.1
Delta distance traveled before/after self-admin0.10.10.20.00.2-0.3-0.20.3-0.30.3-0.30.10.40.4-0.4
Delta ambulatory time before/after self-admin0.81.01.50.50.7-0.8-0.91.0-1.01.1-1.10.91.21.2-1.2
Parametrial fat weight0.10.20.6-0.2-0.20.50.6-0.50.5-0.50.5-0.8-0.4-0.40.4
Pavlov. Cond. lever latency0.60.81.50.10.1-0.3-0.90.9-0.91.0-1.01.21.11.1-1.1
Pavlov. Cond. magazine entry latency0.40.50.90.10.2-0.10.6-0.60.6-0.90.8-0.7-0.9-0.90.9
Pavlov. Cond. change in total contacts0.20.20.50.20.2-0.20.5-0.40.4-0.50.5-0.7-0.5-0.50.5
Pavlov. Cond. index score0.80.91.6-0.00.00.11.0-1.00.9-1.21.1-1.3-1.2-1.21.2
Pavlov. Cond. latency score0.60.71.3-0.00.00.00.8-0.80.8-1.00.9-1.1-1.0-1.01.0
Pavlov. Cond. lever contacts1.21.52.4-0.5-0.50.61.2-1.21.2-1.41.3-1.6-1.4-1.41.4
Pavlov. Cond. magazine entry number0.50.71.1-0.1-0.20.1-0.80.8-0.81.1-0.91.01.11.1-1.1
Pavlov. Cond. intertrial magazine entries6.88.210.83.33.3-3.2-2.92.9-2.92.7-2.72.62.62.6-2.6
Pavlov. Cond. lever-magazine prob. diff.0.70.91.50.00.00.00.9-0.90.9-1.21.1-1.2-1.2-1.21.2
Pavlov. Cond. response bias1.01.21.90.20.2-0.01.1-1.01.0-1.41.2-1.4-1.4-1.41.4
Pavlov. Cond. lever latency1.92.64.72.12.2-2.1-1.71.6-1.61.3-1.31.31.21.2-1.2
Pavlov. Cond. magazine entry latency3.13.84.8-1.9-1.91.92.2-2.12.1-1.91.9-2.0-1.8-1.81.8
Pavlov. Cond. change in total contacts3.75.97.9-2.8-2.82.82.5-2.52.5-2.32.3-2.1-2.2-2.22.2
Pavlov. Cond. index score3.44.66.0-2.4-2.42.52.4-2.22.2-2.02.0-1.9-1.9-1.91.9
Pavlov. Cond. latency score3.64.75.6-2.3-2.22.32.4-2.32.3-2.22.1-2.0-2.0-2.02.0
Pavlov. Cond. lever contacts2.43.35.4-2.3-2.32.32.0-1.91.9-1.51.6-1.6-1.4-1.41.4
Pavlov. Cond. magazine entry number2.73.34.21.71.7-1.9-2.02.0-1.91.8-1.81.81.71.7-1.7
Pavlov. Cond. intertrial magazine entries4.36.57.32.32.3-2.4-2.72.6-2.62.7-2.72.62.62.6-2.6
Pavlov. Cond. lever-magazine prob. diff.4.15.47.0-2.6-2.62.72.5-2.42.4-2.22.2-2.1-2.1-2.12.1
Pavlov. Cond. response bias2.53.35.2-2.3-2.32.32.1-1.91.9-1.61.5-1.6-1.4-1.41.4
Time in closed arm before self-admin4.65.88.3-2.9-2.82.82.3-2.42.4-2.22.4-2.2-2.1-2.12.1
Time in closed arm after self-admin2.72.98.0-2.7-2.82.71.4-1.41.4-1.01.2-0.9-1.0-1.01.0
Time in open arm before self-admin4.65.05.62.32.2-2.2-2.22.3-2.32.2-2.32.42.22.2-2.2
Time in open arm after self-admin4.85.311.13.33.3-3.2-2.12.2-2.21.7-1.81.71.71.7-1.7
Bone: periosteal estimation0.10.20.7-0.7-0.90.70.1-0.10.10.3-0.30.20.30.3-0.3
Bone: periosteal perimeter0.00.00.1-0.1-0.20.20.2-0.20.2-0.10.1-0.3-0.2-0.20.2
Bone: post-yield work2.02.93.61.91.9-1.9-1.81.8-1.81.5-1.51.81.51.5-1.5
Progressive ratio test 1 active lever presses0.30.30.8-0.9-0.80.80.5-0.60.5-0.50.4-0.5-0.4-0.40.4
Progressive ratio test 1 breakpoint0.40.40.8-0.9-0.90.90.7-0.70.6-0.60.5-0.6-0.5-0.50.5
Progressive ratio test 1 inactive lever presses1.52.22.61.11.3-1.3-1.51.5-1.61.5-1.61.51.61.6-1.6
Progressive ratio test 2 active lever presses0.30.31.3-1.1-1.10.90.2-0.20.20.0-0.00.0-0.0-0.00.0
Progressive ratio test 2 breakpoint0.20.31.1-1.1-1.10.90.1-0.20.20.1-0.10.10.00.0-0.0
Progressive ratio test 2 inactive lever presses0.30.50.8-0.4-0.30.0-0.70.6-0.60.8-0.80.90.80.8-0.8
Incentive Sensitization - Responses0.10.20.8-0.8-0.90.7-0.0-0.10.10.2-0.10.10.10.1-0.1
Incentive Sensitization - Breakpoint0.10.20.7-0.7-0.80.7-0.10.0-0.00.3-0.20.30.20.2-0.2
Sum of active levers in priming session hrs 5-60.30.20.90.91.0-0.9-0.30.3-0.30.1-0.10.1-0.1-0.10.1
Progressive ratio0.40.62.7-1.7-1.51.20.1-0.20.20.4-0.20.50.20.2-0.2
Food seeking constrained by brief footshock0.50.60.80.10.4-0.9-0.90.8-0.80.7-0.90.80.80.8-0.8
Seeking ratio, punishment vs. effort0.40.62.11.41.3-1.5-0.50.5-0.5-0.0-0.2-0.00.30.3-0.3
Retroperitoneal fat weight0.10.40.7-0.6-0.50.40.7-0.70.7-0.60.5-0.8-0.6-0.60.6
Reaction time number correct2.95.55.82.32.4-2.3-2.42.4-2.42.3-2.32.22.32.3-2.3
Reaction time mean minus median0.00.00.1-0.1-0.10.10.2-0.10.1-0.30.1-0.2-0.1-0.10.1
Reaction time mean minus median AUC0.00.00.0-0.00.1-0.10.1-0.00.0-0.20.0-0.10.00.0-0.0
Reaction time num false alarms1.31.92.51.51.6-1.5-1.31.3-1.31.4-1.41.01.41.4-1.4
Reaction time num false alarms AUC1.52.32.71.51.5-1.4-1.51.5-1.51.6-1.61.21.61.6-1.6
Reaction time trials correct on left2.95.55.82.32.4-2.3-2.42.4-2.42.3-2.32.22.32.3-2.3
Reaction time trials on left3.05.65.92.32.4-2.3-2.42.4-2.42.3-2.42.32.42.4-2.4
Reaction time mean0.81.22.5-1.6-1.61.51.1-1.01.0-1.00.9-0.7-0.8-0.80.8
Reaction time mean AUC0.40.61.5-1.2-1.21.20.8-0.70.7-0.70.6-0.5-0.5-0.50.5
Median of all reaction times0.60.92.6-1.5-1.61.50.8-0.80.8-0.60.6-0.4-0.5-0.50.5
Reaction time omissions0.71.12.00.30.3-0.3-1.01.0-1.01.1-1.30.91.41.4-1.4
Reaction time false alarm rate0.10.10.20.30.3-0.3-0.30.3-0.30.5-0.50.10.40.4-0.4
Reaction time premature initiation rate0.60.91.60.70.9-0.8-1.01.0-0.91.0-0.91.20.90.9-0.9
Reaction time premature initiations2.24.04.81.92.0-1.9-2.12.0-2.02.0-1.92.21.91.9-1.9
Std. dev. reaction times0.30.51.4-1.2-1.21.10.7-0.60.6-0.60.4-0.4-0.4-0.40.4
Reaction time trials completed3.05.65.92.32.4-2.3-2.42.4-2.42.3-2.42.32.42.4-2.4
Reaction time trials AUC3.15.86.32.42.4-2.3-2.52.5-2.52.4-2.42.32.42.4-2.4
Run reversals in cocaine runway, females0.70.71.2-0.9-1.01.10.9-0.90.9-0.80.8-0.7-0.7-0.70.7
Run reversals in cocaine runway, males0.10.10.2-0.3-0.40.2-0.50.3-0.30.4-0.40.50.40.4-0.4
Latency to leave start box in cocaine runway0.60.71.6-1.3-1.11.00.7-0.80.7-0.60.6-0.7-0.9-0.90.9
Latency to leave start box in cocaine runway, F0.70.81.0-1.0-1.01.00.7-0.70.7-0.80.7-0.8-1.0-1.01.0
Latency to leave start box in cocaine runway, M0.10.10.5-0.7-0.30.30.4-0.40.4-0.20.2-0.3-0.3-0.30.3
Std. dev. time between licks in bursts0.00.00.10.20.2-0.00.10.0-0.10.0-0.1-0.00.20.2-0.2
Total sessions with >9 infusions0.50.62.0-1.4-1.31.20.7-0.70.7-0.40.4-0.4-0.3-0.30.3
Short access day 1 total inactive lever presses0.00.10.1-0.4-0.30.0-0.10.1-0.10.2-0.30.30.30.3-0.3
Short access day 10 total inactive lever presses0.10.20.30.50.5-0.5-0.30.3-0.30.3-0.40.30.40.4-0.4
Short access day 1 total infusions0.10.20.4-0.6-0.50.3-0.30.2-0.20.5-0.50.60.40.4-0.4
Short access day 10 total infusions0.60.81.2-1.1-0.90.91.0-1.01.0-0.80.7-0.9-0.8-0.80.8
Short access total infusions0.50.72.1-1.5-1.31.30.7-0.70.7-0.40.4-0.4-0.4-0.40.4
Short access day 1 locomotion0.60.71.9-1.4-1.31.20.8-0.80.8-0.50.6-0.5-0.6-0.60.6
Short access day 10 total locomotion1.01.93.1-0.7-0.40.81.6-1.51.5-1.61.5-1.8-1.5-1.51.5
Short access total locomotion0.40.50.8-0.9-0.80.90.7-0.70.7-0.60.5-0.6-0.5-0.50.5
One hour access (0.3 mA shock)0.10.10.40.50.6-0.5-0.20.1-0.20.0-0.10.1-0.1-0.10.1
Compulsive drug intake0.40.51.91.41.3-1.1-0.50.6-0.60.3-0.30.40.20.2-0.2
One hour access (shock baseline)0.00.00.1-0.3-0.10.10.1-0.10.10.0-0.10.1-0.1-0.10.1
Social response proportion0.30.41.2-1.0-1.11.0-0.30.2-0.20.6-0.40.50.50.5-0.5
Social responses0.10.20.6-0.7-0.80.70.2-0.20.2-0.00.1-0.10.00.0-0.0
Social time1.41.83.2-0.2-0.20.1-1.21.2-1.21.6-1.61.71.81.8-1.8
Soleus weight0.61.76.32.52.4-2.0-0.81.0-1.00.4-0.60.40.40.4-0.4
Bone: stiffness0.71.21.41.11.1-1.1-1.21.2-1.21.1-1.11.21.01.0-1.0
Tibialis anterior weight0.41.33.11.81.7-1.6-1.11.1-1.10.9-0.90.80.70.7-0.7
Time to tail flick, vehicle, before self-admin0.70.71.41.11.2-1.2-0.70.8-0.80.6-0.70.60.60.6-0.6
Time to tail flick, vehicle, after self-admin0.10.20.30.20.30.10.5-0.40.4-0.50.4-0.4-0.6-0.60.6
Time to tail flick, test, before self-admin0.20.20.7-0.9-0.80.80.3-0.40.4-0.30.2-0.3-0.2-0.20.2
Time to tail flick, test, after self-admin1.21.22.01.41.4-1.2-1.11.1-1.11.0-1.01.00.90.9-0.9
Delta time to tail flick, vehicle, before/after SA0.10.00.20.40.5-0.10.1-0.00.0-0.20.1-0.2-0.2-0.20.2
Delta time to tail flick, test, before/after SA1.61.62.71.61.5-1.4-1.21.3-1.31.2-1.21.21.11.1-1.1
Tibia length0.10.30.50.30.4-0.5-0.60.5-0.60.7-0.70.30.70.7-0.7
Ambulatory time before self-admin0.71.11.2-0.9-1.01.01.0-1.01.0-1.01.0-1.0-1.1-1.11.1
Ambulatory time after self-admin0.00.10.2-0.5-0.30.30.2-0.20.2-0.20.1-0.3-0.1-0.10.1
Bone: tissue strength0.00.00.1-0.4-0.30.10.1-0.10.10.0-0.1-0.20.10.1-0.1
Total heroin consumption2.32.75.52.42.3-2.3-1.61.6-1.61.2-1.31.31.11.1-1.1
Bone: trabecular number0.30.51.11.01.0-1.0-0.50.5-0.50.4-0.50.20.70.7-0.7
Bone: trabecular spacing0.10.10.3-0.5-0.50.60.3-0.30.3-0.20.2-0.0-0.3-0.30.3
Bone: trabecular thickness0.00.00.10.1-0.0-0.00.2-0.20.1-0.20.1-0.3-0.1-0.10.1
Bone: trabecular tissue density0.10.10.2-0.3-0.30.20.2-0.30.3-0.30.3-0.4-0.5-0.50.5
Water consumed over 24 hours1.72.23.01.10.9-1.3-1.61.6-1.61.7-1.71.51.61.6-1.6
Number of responses in last shaping day0.00.00.1-0.3-0.30.30.2-0.10.1-0.00.0-0.00.10.1-0.1