Hub : Genes

C5h1orf127

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	intron excision ratio	chr5_164374718_164375873	0.02	0.02	2.1e-03	0.01	0.01	-0	0.01	9.8e-03	1.3e-02	4.1e-01	1.6e-02
2	Liver	mRNA stability	C5h1orf127	0.02	0.02	2.4e-03	0.01	0.01	0.01	0.01	9.2e-03	1.9e-02	5.3e-02	1.8e-02
3	Liver	gene expression	C5h1orf127	0.1	0.07	6.2e-10	0.07	0.06	0.06	0.07	1.7e-08	9.6e-08	3.3e-07	2.0e-08
4	Adipose	gene expression	C5h1orf127	0.04	0.04	4.6e-04	0.02	0.02	0.01	0.02	1.6e-03	4.4e-03	3.9e-02	3.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.0	0.0	0.1	0.2	-0.3	-0.2	-0.2
Area under the delay curve	1.1	1.3	2.0	1.4	-0.8	-1.3	-0.9
BMI with tail	0.0	0.1	0.1	0.1	-0.3	-0.1	0.4
BMI without tail	0.1	0.2	0.3	-0.5	0.2	0.6	0.2
Body weight	0.3	1.3	1.7	-1.1	0.8	1.3	1.3
Weight adjusted by age	1.5	2.2	2.8	-1.7	1.4	1.6	1.2
Bone surface	0.4	0.8	0.9	-1.0	0.8	0.9	0.8
Bone volume	0.1	0.2	0.2	-0.4	0.4	0.5	0.3
Breakpoint value in progressive ratio session	0.3	0.4	0.7	-0.6	-0.1	0.7	0.8
Number of licking bursts	1.0	1.6	1.8	1.2	-1.3	-1.2	-1.4
Context. condit. distance diff. score	4.0	4.9	5.4	2.3	-2.0	-2.3	-2.2
Locomotion velocity, session 1	0.1	0.1	0.3	0.2	-0.5	-0.2	-0.3
Locomotion distance, session 1	0.0	0.0	0.1	0.0	-0.3	-0.1	-0.1
Locomotion velocity, session 2	0.4	0.5	0.6	0.8	-0.7	-0.7	-0.7
Locomotion distance, session 2	0.1	0.1	0.2	-0.4	0.1	0.4	0.3
Locomotion velocity, session 3	0.8	1.0	1.0	1.0	-1.0	-0.9	-1.0
Locomotion distance, session 3	0.5	0.6	0.7	0.8	-0.7	-0.8	-0.8
Stereotopy head waving bouts, day 3	0.0	0.0	0.1	-0.2	-0.1	0.2	0.1
Stereotopy head waving duration, day 3	0.1	0.1	0.2	-0.4	0.2	0.4	0.4
Locomotion velocity, session 7	0.0	0.0	0.0	0.1	-0.1	-0.1	-0.1
Locomotion distance, session 7	0.1	0.1	0.2	-0.4	0.2	0.4	0.4
Stereotopy head waving bouts, day 7	2.3	2.6	3.0	1.6	-1.4	-1.6	-1.7
Stereotopy head waving duration, day 7	1.2	1.4	1.8	1.2	-0.9	-1.2	-1.3
Locomotion velocity, session 8	2.3	2.8	3.6	1.6	-1.9	-1.6	-1.6
Locomotion distance, session 8	2.2	3.2	3.6	1.8	-1.9	-1.7	-1.8
Degree of sensitization distance	0.3	0.3	0.4	-0.6	0.4	0.6	0.6
Degree of sensitization stereotypy	0.8	0.9	1.1	1.0	-0.7	-1.0	-1.1
Conditioned locomotion	3.5	4.0	4.3	2.0	-1.9	-2.1	-2.0
Cocaine response after cond. corrected	0.8	0.9	1.1	-1.0	0.9	1.0	0.9
Cocaine response after cond. not corrected	0.7	0.8	1.0	-1.0	0.9	0.9	0.8
Cocaine response before conditioning	0.0	0.0	0.0	-0.0	-0.0	0.1	0.1
Saline control response	0.6	0.8	1.1	-1.0	0.6	0.9	0.9
Bone: connectivity density	0.0	0.0	0.0	-0.1	-0.1	-0.1	-0.1
Bone: cortical apparent density	2.1	2.8	4.5	-1.4	2.1	1.5	1.6
Bone: cortical area	1.3	2.0	2.1	-1.4	1.2	1.5	1.4
Bone: cortical porosity	1.1	1.2	1.4	1.0	-1.2	-1.0	-1.1
Bone: cortical porosity	0.8	0.8	1.1	0.8	-1.1	-0.9	-1.0
Bone: cortical thickness	0.6	1.0	1.1	-1.0	0.9	1.0	1.0
Bone: cortical thickness	0.3	0.3	0.4	-0.6	0.6	0.6	0.5
Bone: cortical tissue density	2.1	2.8	4.4	-1.4	2.1	1.5	1.6
Condit. Reinf. active minus inactive responses	0.8	0.9	1.1	-1.0	0.8	1.0	1.0
Condit. Reinf. active-inactive response ratio	2.3	2.5	3.0	-1.5	1.7	1.5	1.5
Condit. Reinf. active responses	0.0	0.0	0.0	-0.0	-0.1	0.1	0.1
Condit. Reinf. inactive responses	3.2	3.9	4.2	2.0	-2.0	-2.0	-2.0
Incentive salience index mean	3.3	4.1	4.4	-2.0	1.9	2.1	2.1
Condit. Reinf. lever presses	3.0	4.2	4.5	-2.0	2.0	2.1	2.0
Condit. Reinf. active minus inactive responses	0.6	0.8	1.0	1.0	-0.8	-0.8	-1.0
Condit. Reinf. active-inactive response ratio	0.3	0.4	0.5	0.7	-0.4	-0.5	-0.7
Condit. Reinf. active responses	0.8	1.2	1.4	1.2	-1.0	-1.0	-1.1
Condit. Reinf. inactive responses	0.0	0.0	0.1	-0.2	0.1	0.3	0.2
Condit. Reinf. lever presses	0.0	0.0	0.2	0.1	-0.4	-0.1	-0.1
Condit. Reinf. lever reinforcers received	0.7	1.0	1.2	1.1	-1.0	-0.9	-1.1
Conditioned reinforcement - actives	0.6	1.1	1.3	0.9	-1.1	-1.0	-1.1
Conditioned reinforcement - inactives	0.1	0.1	0.2	0.3	-0.0	-0.2	-0.4
Conditioned locomotion	0.8	1.1	1.3	0.9	-1.1	-1.0	-1.1
Patch foraging indifference point 0 sec	0.5	0.9	1.2	-1.1	0.8	1.0	0.9
Patch foraging indifference point AUC	0.3	0.5	0.8	-0.6	0.9	0.6	0.7
Delay disc. indifference point, 0s delay	1.1	1.2	1.5	1.2	-0.7	-1.2	-1.1
Delay disc. indifference point, 16s delay	1.2	1.3	1.6	1.3	-1.2	-1.2	-0.9
Delay disc. indifference point, 2s delay	0.9	1.0	1.6	1.1	-0.4	-1.0	-1.3
Delay disc. indifference point, 24s delay	0.5	0.6	1.3	-0.6	0.3	0.6	1.1
Delay disc. indifference point, 4s delay	0.6	0.6	1.0	1.0	-0.3	-0.9	-0.8
Delay disc. indifference point, 8s delay	0.3	0.3	0.5	0.7	-0.4	-0.7	-0.3
Indifference point function ln k	0.1	0.2	0.3	0.5	-0.3	-0.4	-0.5
Indifference point function log k	0.1	0.2	0.3	0.5	-0.3	-0.4	-0.5
Patch foraging total patch changes 0 sec	0.5	1.0	1.3	-1.1	0.7	1.1	1.0
Patch foraging total patch changes 12 sec	1.0	1.3	1.5	-1.2	1.0	1.2	1.2
Patch foraging total patch changes 18 sec	0.5	0.8	1.0	-0.9	0.7	1.0	1.0
Patch foraging total patch changes 24 sec	0.5	0.9	1.3	-1.0	0.8	0.9	1.1
Patch foraging total patch changes 6 sec	1.9	2.9	3.3	-1.6	1.8	1.7	1.6
Patch foraging time to switch 0 sec	1.0	2.0	2.7	-1.5	0.9	1.7	1.4
Patch foraging water rate 0 sec	0.8	1.7	2.2	1.4	-0.9	-1.5	-1.3
Patch foraging water rate 12 sec	0.0	0.1	0.1	0.2	-0.1	-0.4	-0.3
Patch foraging water rate 18 sec	0.0	0.0	0.0	-0.2	0.2	0.1	0.2
Patch foraging water rate 24 sec	0.3	0.4	0.5	-0.6	0.7	0.5	0.6
Patch foraging water rate 6 sec	0.5	0.7	1.0	0.8	-0.8	-1.0	-0.8
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.2	-0.4	0.0	0.3	0.3
Distance traveled before self-admin	0.1	0.1	0.3	0.1	-0.1	-0.1	-0.6
Distance traveled after self-admin	0.1	0.1	0.1	-0.3	0.3	0.3	-0.0
Extensor digitorum longus weight	0.2	0.6	0.7	0.8	-0.8	-0.8	-0.7
Bone: elastic displacement	6.5	7.5	9.2	2.6	-3.0	-2.7	-2.7
Bone: elastic work	3.6	4.7	6.0	2.0	-2.4	-2.1	-2.1
Bone: endosteal estimation	1.0	2.2	2.6	-1.5	1.3	1.6	1.5
Bone: endosteal perimeter	0.7	1.4	1.7	-1.2	1.0	1.3	1.2
Epididymis fat weight	1.1	3.8	5.2	-2.0	1.5	2.0	2.3
Delta time in closed arm before/after self-admin	0.0	0.0	0.1	-0.0	0.2	0.2	-0.3
Delta time in open arm before/after self-admin	0.1	0.1	0.4	-0.4	-0.1	0.3	0.6
Diff in mean of infusions in LGA sessions	0.2	0.2	0.3	0.4	-0.5	-0.4	-0.6
Delay discount exponential model param	1.0	1.1	1.6	-1.3	0.7	1.2	0.8
Extinction: sum of active levers before priming	0.0	0.0	0.1	0.1	0.2	-0.1	-0.3
Active lever presses in extinction session 6	0.1	0.1	0.2	-0.4	0.2	0.4	0.3
Bone: final force	0.9	1.5	1.7	-1.1	1.3	1.2	1.2
Bone: final moment	0.4	0.6	0.8	-0.7	0.9	0.8	0.7
Food consumed during 24 hour testing period	0.0	0.0	0.0	-0.1	-0.1	0.2	-0.1
Glucose	0.1	0.1	0.2	0.3	-0.3	-0.4	-0.1
Heart weight	14.9	23.0	28.6	4.8	-5.3	-4.5	-4.4
Delay discount hyperbolic model param	1.3	1.4	2.1	-1.4	0.8	1.3	1.0
Intermittent access intake day 1-15 change	0.2	0.5	0.8	0.8	-0.5	-0.6	-0.9
Intermittent access intake escalation	0.2	0.4	0.8	0.7	-0.3	-0.5	-0.9
Intermittent access intake escalation 2	0.4	0.5	0.6	0.8	-0.7	-0.5	-0.7
Intermitt. access day 1 inactive lever presses	0.0	0.1	0.1	-0.3	0.3	0.3	0.3
Intermitt. access day 15 inactive lever presses	0.2	0.4	0.6	-0.8	0.6	0.7	0.4
Intermitt. access escalation Index	0.0	0.1	0.2	0.2	-0.4	-0.1	-0.2
Intermittent access day 1 total infusions	2.1	3.3	4.0	-2.0	1.9	1.8	1.6
Intermittent access day 15 total infusions	1.2	1.8	2.6	-1.4	1.6	1.4	0.9
Intermittent access terminal intake (last 3 days)	3.7	4.9	5.5	-2.3	2.2	2.3	2.0
Intermittent access total infusions	4.1	4.9	5.4	-2.3	2.3	2.2	1.9
Intermittent access day 1 locomotion	3.8	4.8	5.4	-2.3	2.1	2.2	2.0
Intermittent access day 15 total locomotion	0.5	1.0	1.4	-1.2	1.0	1.0	0.8
Intermittent access total locomotion	2.3	2.7	3.2	-1.8	1.6	1.7	1.4
Intermittent access standard deviation	0.1	0.2	0.2	-0.5	0.4	0.4	0.4
Left kidney weight	0.0	0.0	0.1	0.1	-0.2	0.0	0.2
Right kidney weight	0.0	0.1	0.1	-0.1	-0.4	0.1	0.2
Cocaine induced anxiety	0.7	1.0	1.3	0.9	-1.1	-0.8	-1.1
Post-drug Anxiety	0.9	1.0	1.7	0.9	-0.9	-0.9	-1.3
Baseline Anxiety	0.2	0.2	0.4	-0.4	0.6	0.4	0.3
Tail length	0.4	1.7	2.6	-1.5	1.1	1.6	0.9
Length with tail	0.6	2.5	3.4	-1.7	1.3	1.8	1.5
Length without tail	0.1	0.3	0.6	0.6	-0.8	-0.5	-0.2
Times rat made contact with spout	0.1	0.1	0.2	-0.4	0.2	0.5	0.3
Lifetime Intake	3.9	4.7	5.3	-2.3	2.2	2.2	1.9
Liver weight, left	4.5	7.4	9.0	-2.8	2.3	2.8	3.0
Liver weight, right	2.8	4.9	5.8	-2.3	1.9	2.2	2.4
Locomotor activity	3.3	5.2	6.1	2.2	-2.5	-2.2	-2.2
Locomotor testing distance	1.6	3.0	3.4	1.7	-1.8	-1.7	-1.7
Locomotor testing rearing	0.2	0.4	0.4	-0.6	0.5	0.6	0.6
Locomotion in novel chamber	1.6	2.1	2.9	1.7	-0.9	-1.6	-1.3
Locomotion in novel chamber post-restriction	3.4	5.6	6.5	2.5	-2.1	-2.3	-2.5
Fecal boli incidents, locomotor time 1	1.4	2.0	2.6	-1.6	1.3	1.4	1.3
Change in fecal boli incidents, locomotor task	2.0	1.9	2.2	1.5	-1.3	-1.3	-1.5
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.1	0.2	-0.2	-0.2	-0.3
Bouts of movement, locomotor time 1	1.6	1.8	2.1	-1.3	1.4	1.4	1.2
Total resting periods, locomotor time 1	2.6	2.9	3.0	-1.7	1.7	1.7	1.7
Rest time, locomotor task time 1	0.4	0.5	0.6	0.7	-0.7	-0.8	-0.6
Distance moved, locomotor task time 1	0.0	0.1	0.2	-0.0	-0.0	0.4	-0.3
Vertical activity count, locomotor time 1	0.1	0.2	0.4	0.4	-0.1	0.0	-0.6
Time >=10cm from walls, locomotor time 2	0.5	0.8	1.4	-0.9	1.2	0.9	0.4
Bouts of movement, locomotor time 2	0.0	0.1	0.2	-0.2	0.2	-0.1	0.4
Total resting periods, locomotor time 2	0.0	0.0	0.1	0.2	-0.0	-0.4	0.1
Rest time, locomotor task time 2	1.5	1.9	2.6	1.4	-1.6	-1.6	-0.8
Distance moved, locomotor task time 2	0.6	0.7	1.4	-0.8	0.8	1.2	0.3
Vertical activity count, locomotor time 2	0.1	0.1	0.3	0.1	0.0	0.2	-0.5
Light reinforcement 1	0.2	0.6	0.9	0.8	-0.5	-0.8	-1.0
Light reinforcement 2	0.0	0.0	0.0	0.0	0.0	0.0	-0.2
Bone: marrow area	0.8	1.8	2.1	-1.4	1.1	1.5	1.3
Bone: maximum diameter	1.1	2.0	2.3	-1.4	1.2	1.5	1.5
Bone: maximum force	1.2	2.1	2.2	-1.4	1.4	1.5	1.4
Bone: maximum moment	0.5	0.8	0.9	-0.9	0.9	1.0	0.8
Mean time between licks in bursts	0.5	1.2	1.5	-1.1	1.0	1.0	1.2
Mean num. licks in bursts	1.9	2.9	3.2	-1.7	1.6	1.8	1.7
Cd content in liver	0.2	0.2	0.3	0.5	-0.2	-0.3	-0.6
Co content in liver	0.8	0.9	1.0	1.0	-1.0	-1.0	-0.9
Cu content in liver	0.6	0.7	0.9	0.9	-0.9	-0.9	-0.7
Fe content in liver	0.3	0.4	0.6	-0.5	0.6	0.5	0.7
K content in liver	0.2	0.2	0.3	0.4	-0.6	-0.4	-0.4
Mg content in liver	0.3	0.3	0.4	-0.6	0.3	0.6	0.6
Mn content in liver	0.6	0.7	0.9	-0.9	0.7	0.8	1.0
Na content in liver	0.4	0.4	0.7	0.5	-0.8	-0.6	-0.4
Rb content in liver	0.2	0.2	0.4	-0.5	0.2	0.6	0.5
Se content in liver	2.3	2.7	2.8	-1.6	1.7	1.6	1.7
Sr content in liver	0.2	0.2	0.5	-0.3	0.7	0.3	0.4
Zn content in liver	0.1	0.1	0.1	-0.3	0.2	0.3	0.3
Bone: minimum diameter	2.6	4.7	5.3	-2.3	2.0	2.2	2.2
Time in familiar zone, hab. session 1	0.5	0.5	0.5	0.7	-0.7	-0.7	-0.7
Time in novel zone, hab. session 1	0.5	0.5	0.5	-0.7	0.6	0.7	0.7
Total zone transitions, hab. session 1	0.1	0.2	0.3	-0.6	-0.0	0.5	0.3
Total locomotion distance, hab. session 1	0.1	0.1	0.4	0.1	-0.6	-0.1	-0.3
Locomotion velocity, hab. session 1	0.2	0.3	0.7	0.3	-0.9	-0.3	-0.5
Time in familiar zone, hab. session 2	0.9	1.0	1.2	1.1	-0.7	-1.0	-1.1
Time in novel zone, hab. session 2	0.0	0.0	0.1	-0.2	0.0	0.2	0.3
Total zone transitions, hab. session 2	0.7	0.9	1.2	0.9	-1.1	-0.9	-1.0
Total locomotion distance, hab. session 2	1.6	2.1	2.2	1.4	-1.5	-1.4	-1.5
Locomotion velocity, hab. session 2	0.8	1.1	1.4	0.9	-1.2	-1.0	-1.1
Novel to familiar place preference ratio	0.8	0.8	0.9	-1.0	0.9	0.9	0.9
Novelty place preference	0.6	0.6	0.7	-0.8	0.8	0.8	0.7
Time in novel zone, NPP test	0.4	0.4	0.5	-0.7	0.7	0.6	0.6
Total zone transitions, NPP test	2.3	3.3	3.5	1.8	-1.8	-1.7	-1.9
Total locomotion distance, NPP test	2.2	3.1	3.4	1.7	-1.8	-1.7	-1.9
Locomotion velocity, NPP test	2.0	2.9	3.5	1.6	-1.9	-1.6	-1.7
Intraocular pressure	0.4	0.5	0.8	-0.7	0.8	0.9	0.6
Delta distance traveled before/after self-admin	0.4	0.4	0.7	-0.7	0.4	0.6	0.8
Delta ambulatory time before/after self-admin	1.1	1.3	1.7	-1.3	0.8	1.1	1.3
Parametrial fat weight	1.0	2.4	2.5	-1.6	1.6	1.5	1.6
Pavlov. Cond. lever latency	0.4	0.6	0.7	0.7	-0.6	-0.8	-0.8
Pavlov. Cond. magazine entry latency	1.3	1.7	2.5	-1.1	1.6	1.2	1.3
Pavlov. Cond. change in total contacts	0.4	0.4	0.5	-0.6	0.5	0.6	0.7
Pavlov. Cond. index score	1.4	1.8	2.3	-1.2	1.5	1.3	1.3
Pavlov. Cond. latency score	0.8	1.0	1.2	-0.9	1.1	1.0	1.0
Pavlov. Cond. lever contacts	0.8	0.9	1.1	-0.9	1.1	1.0	1.0
Pavlov. Cond. magazine entry number	1.0	1.3	2.2	1.0	-1.5	-1.0	-1.0
Pavlov. Cond. intertrial magazine entries	1.2	1.5	2.0	1.1	-1.4	-1.1	-1.1
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.2	2.8	-1.3	1.7	1.5	1.5
Pavlov. Cond. response bias	1.1	1.4	2.3	-1.0	1.5	1.1	1.1
Pavlov. Cond. lever latency	0.5	0.7	0.9	-0.9	1.0	0.8	0.8
Pavlov. Cond. magazine entry latency	0.0	0.0	0.0	-0.2	0.2	0.1	0.2
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	0.1	-0.2	-0.1	-0.2
Pavlov. Cond. index score	0.0	0.0	0.0	0.1	-0.2	-0.1	-0.0
Pavlov. Cond. latency score	0.0	0.0	0.0	0.0	-0.1	-0.1	-0.0
Pavlov. Cond. lever contacts	0.5	0.7	0.9	0.8	-1.0	-0.8	-0.8
Pavlov. Cond. magazine entry number	0.1	0.1	0.1	-0.3	0.2	0.4	0.3
Pavlov. Cond. intertrial magazine entries	1.0	1.5	1.6	-1.2	1.2	1.3	1.2
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.0	-0.0	-0.1	-0.0	0.0
Pavlov. Cond. response bias	0.5	0.7	1.0	0.9	-1.0	-0.8	-0.8
Time in closed arm before self-admin	0.2	0.3	0.3	-0.5	0.6	0.4	0.5
Time in closed arm after self-admin	0.1	0.1	0.5	-0.2	0.7	0.3	-0.1
Time in open arm before self-admin	1.9	2.1	2.4	1.5	-1.4	-1.4	-1.5
Time in open arm after self-admin	0.9	1.0	1.8	0.9	-1.3	-0.9	-0.6
Bone: periosteal estimation	1.7	3.5	4.0	-2.0	1.7	2.0	1.9
Bone: periosteal perimeter	0.6	1.0	1.3	-1.1	0.8	1.1	1.0
Bone: post-yield work	0.9	1.2	1.5	-1.1	1.2	1.2	1.0
Progressive ratio test 1 active lever presses	0.3	0.4	0.8	-0.6	0.9	0.4	0.3
Progressive ratio test 1 breakpoint	0.4	0.4	1.0	-0.7	1.0	0.5	0.4
Progressive ratio test 1 inactive lever presses	0.2	0.3	0.7	-0.5	0.9	0.5	0.2
Progressive ratio test 2 active lever presses	2.9	3.4	4.2	-1.9	2.1	1.9	1.6
Progressive ratio test 2 breakpoint	3.1	3.5	4.3	-1.9	2.1	1.9	1.6
Progressive ratio test 2 inactive lever presses	0.6	1.0	1.7	-1.0	1.3	1.0	0.5
Incentive Sensitization - Responses	1.3	1.8	2.0	-1.4	1.3	1.4	1.2
Incentive Sensitization - Breakpoint	1.5	2.0	2.3	-1.5	1.4	1.5	1.3
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	-0.3	0.1	0.4	0.1
Progressive ratio	0.0	0.1	0.1	0.3	-0.3	-0.4	-0.1
Food seeking constrained by brief footshock	1.6	1.9	2.6	1.2	-1.3	-1.4	-1.6
Seeking ratio, punishment vs. effort	0.3	0.5	0.7	0.6	-0.7	-0.6	-0.9
Retroperitoneal fat weight	0.4	1.5	2.7	-1.2	0.9	1.1	1.6
Reaction time number correct	0.9	1.7	2.4	1.4	-1.0	-1.3	-1.6
Reaction time mean minus median	0.7	1.8	1.9	-1.3	1.4	1.3	1.3
Reaction time mean minus median AUC	0.1	0.2	0.3	-0.6	0.3	0.6	0.4
Reaction time num false alarms	0.1	0.2	0.6	-0.1	0.8	0.2	0.1
Reaction time num false alarms AUC	0.0	0.1	0.1	0.3	0.2	-0.2	-0.3
Reaction time trials correct on left	0.9	1.7	2.4	1.4	-1.0	-1.3	-1.6
Reaction time trials on left	0.8	1.5	2.2	1.3	-0.9	-1.2	-1.5
Reaction time mean	0.1	0.1	0.2	-0.4	0.4	0.4	0.3
Reaction time mean AUC	0.2	0.3	0.3	-0.6	0.5	0.5	0.5
Median of all reaction times	0.0	0.0	0.0	-0.1	0.1	0.1	-0.1
Reaction time omissions	1.1	1.6	2.0	-1.4	1.0	1.2	1.4
Reaction time false alarm rate	0.3	0.3	0.6	-0.5	0.8	0.5	0.5
Reaction time premature initiation rate	3.1	4.3	5.3	-2.0	2.0	1.9	2.3
Reaction time premature initiations	0.8	1.4	1.9	-1.1	1.4	1.1	1.2
Std. dev. reaction times	0.7	1.3	1.5	-1.2	1.1	1.1	1.1
Reaction time trials completed	0.8	1.5	2.2	1.3	-0.9	-1.2	-1.5
Reaction time trials AUC	0.9	1.6	2.4	1.4	-0.9	-1.2	-1.5
Run reversals in cocaine runway, females	0.9	0.9	1.3	0.8	-1.1	-1.0	-0.7
Run reversals in cocaine runway, males	0.9	0.9	1.6	0.9	-1.3	-0.9	-0.6
Latency to leave start box in cocaine runway	0.0	0.0	0.1	-0.2	0.1	0.3	0.1
Latency to leave start box in cocaine runway, F	0.5	0.5	0.8	-0.8	0.6	0.9	0.6
Latency to leave start box in cocaine runway, M	0.7	0.7	0.7	0.8	-0.9	-0.8	-0.7
Std. dev. time between licks in bursts	0.8	1.1	1.8	0.8	-1.3	-1.1	-0.8
Total sessions with >9 infusions	0.7	0.9	0.9	-1.0	1.0	0.8	1.0
Short access day 1 total inactive lever presses	0.4	0.5	0.7	-0.7	0.7	0.5	0.8
Short access day 10 total inactive lever presses	0.1	0.1	0.3	0.4	-0.2	-0.3	-0.6
Short access day 1 total infusions	1.1	1.5	1.9	-1.3	1.4	1.3	0.9
Short access day 10 total infusions	1.2	1.5	1.7	-1.3	1.2	1.1	1.3
Short access total infusions	1.7	2.1	2.4	-1.5	1.5	1.4	1.3
Short access day 1 locomotion	0.1	0.1	0.1	-0.4	0.4	0.2	0.2
Short access day 10 total locomotion	0.0	0.0	0.1	-0.0	-0.2	-0.3	0.1
Short access total locomotion	0.1	0.1	0.2	-0.3	0.2	-0.0	0.4
One hour access (0.3 mA shock)	2.0	2.3	2.6	-1.6	1.4	1.6	1.5
Compulsive drug intake	0.1	0.1	0.2	-0.1	-0.5	0.0	0.3
One hour access (shock baseline)	0.8	1.2	1.6	-1.2	1.3	1.1	0.9
Social response proportion	1.7	1.9	2.2	-1.5	1.2	1.4	1.4
Social responses	0.1	0.1	0.2	-0.4	0.1	0.3	0.2
Social time	0.6	0.8	0.9	0.9	-0.7	-1.0	-0.9
Soleus weight	0.1	0.4	0.7	0.5	-0.8	-0.5	-0.6
Bone: stiffness	3.2	5.2	6.1	-2.1	2.5	2.2	2.3
Tibialis anterior weight	0.0	0.1	0.3	-0.1	0.6	0.1	0.3
Time to tail flick, vehicle, before self-admin	0.5	0.5	0.7	0.6	-0.8	-0.6	-0.8
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.1	0.1	-0.3	-0.1	0.1
Time to tail flick, test, before self-admin	1.5	1.6	1.8	1.3	-1.4	-1.3	-1.1
Time to tail flick, test, after self-admin	1.8	1.9	3.7	1.2	-1.9	-1.2	-0.9
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.5	-0.5	0.7	0.5	0.7
Delta time to tail flick, test, before/after SA	0.1	0.1	0.2	0.2	-0.5	-0.1	-0.1
Tibia length	2.0	5.6	6.3	-2.3	2.5	2.3	2.3
Ambulatory time before self-admin	0.1	0.2	0.6	0.3	-0.2	-0.3	-0.8
Ambulatory time after self-admin	0.5	0.6	0.9	-0.9	0.7	0.8	0.5
Bone: tissue strength	0.1	0.1	0.1	0.4	-0.2	-0.2	-0.4
Total heroin consumption	0.0	0.0	0.1	-0.1	-0.4	0.1	0.1
Bone: trabecular number	0.2	0.3	0.4	0.6	-0.5	-0.6	-0.6
Bone: trabecular spacing	0.1	0.1	0.1	0.3	-0.2	-0.3	-0.3
Bone: trabecular thickness	0.2	0.2	0.4	0.5	-0.4	-0.4	-0.6
Bone: trabecular tissue density	0.1	0.2	0.4	-0.3	0.6	0.3	0.4
Water consumed over 24 hours	0.0	0.0	0.1	0.0	-0.2	0.1	-0.2
Number of responses in last shaping day	1.0	1.1	1.6	1.2	-0.5	-1.1	-1.3