Hub : Genes

C2h4orf17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr2_229380762_229383931 0.02 0.01 4.2e-03 0.01 0.02 0.02 0.01 1.5e-02 6.2e-04 1.2e-03 2.0e-03
2 NAcc intron excision ratio chr2_229372719_229373788 0.04 0.02 2.5e-05 0.04 0.03 0.03 0.03 2.9e-06 2.4e-05 9.6e-05 1.4e-05
3 IC intron excision ratio chr2_229373931_229380698 0.11 0.07 6.7e-03 0.06 0.02 0.05 0.04 1.6e-03 4.2e-02 4.9e-03 8.2e-03
4 NAcc intron excision ratio chr2_229372719_229380698 0.18 0.09 0.0e+00 0.15 0.16 0.17 0.15 9.4e-22 1.4e-23 1.0e-25 1.1e-22
5 BLA gene expression C2h4orf17 0.12 0.07 2.1e-04 0.07 0.05 0.05 0.06 8.9e-05 9.8e-04 1.0e-03 2.6e-04
6 NAcc gene expression C2h4orf17 0.12 0.08 3.4e-07 0.04 0.05 0.05 0.04 1.2e-06 2.7e-08 4.0e-08 2.4e-07
7 IC intron excision ratio chr2_229372719_229380698 0.12 0.07 4.7e-03 0 0.04 0.05 0.03 3.0e-01 8.7e-03 5.2e-03 3.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.71.22.81.71.1-0.6-1.2-1.5-0.1-0.6
Area under the delay curve0.00.00.10.20.40.2-0.0-0.2-0.1-0.1
BMI with tail0.51.83.8-1.9-1.2-0.31.81.4-1.10.8
BMI without tail0.73.66.3-1.7-1.7-1.52.51.8-2.31.5
Body weight0.83.77.3-2.7-2.0-0.62.42.1-1.61.2
Weight adjusted by age0.10.31.5-0.60.2-0.1-0.3-0.2-0.01.2
Bone surface0.40.71.81.40.6-0.7-0.8-1.0-0.6-0.4
Bone volume0.30.71.71.20.2-1.3-0.5-0.5-0.80.1
Breakpoint value in progressive ratio session0.40.71.5-0.20.91.2-0.3-1.11.0-0.6
Number of licking bursts0.61.75.1-1.30.42.30.0-0.31.8-1.2
Context. condit. distance diff. score1.61.93.30.31.41.7-1.1-1.31.8-1.3
Locomotion velocity, session 11.71.94.3-2.1-1.90.11.41.3-0.81.2
Locomotion distance, session 11.62.06.8-2.6-1.21.61.21.00.90.5
Locomotion velocity, session 20.10.10.4-0.6-0.10.1-0.0-0.3-0.00.3
Locomotion distance, session 22.02.88.3-2.9-1.61.41.71.40.51.1
Locomotion velocity, session 31.61.83.7-1.9-1.71.01.91.30.30.0
Locomotion distance, session 30.30.30.8-0.6-0.10.90.70.00.7-0.4
Stereotopy head waving bouts, day 31.41.72.9-1.3-1.7-0.61.71.5-0.71.1
Stereotopy head waving duration, day 31.11.42.6-1.5-1.6-0.31.41.5-0.40.8
Locomotion velocity, session 70.70.82.4-1.6-0.50.91.00.60.40.6
Locomotion distance, session 71.21.64.9-1.20.82.20.2-0.51.8-0.6
Stereotopy head waving bouts, day 72.02.44.2-0.4-2.1-1.41.61.8-1.31.6
Stereotopy head waving duration, day 72.12.65.2-0.6-2.3-1.21.62.2-1.11.6
Locomotion velocity, session 80.20.20.4-0.7-0.10.60.70.10.40.4
Locomotion distance, session 81.72.57.1-2.5-0.22.70.60.01.9-0.2
Degree of sensitization distance0.70.81.5-0.11.21.0-0.9-1.01.0-0.4
Degree of sensitization stereotypy1.92.13.20.1-1.7-1.81.31.4-1.61.5
Conditioned locomotion1.61.96.01.3-0.6-2.50.30.4-1.81.2
Cocaine response after cond. corrected0.30.41.00.3-0.4-1.00.40.1-1.00.6
Cocaine response after cond. not corrected0.50.71.90.90.1-1.30.2-0.3-1.40.7
Cocaine response before conditioning0.10.10.20.20.3-0.20.1-0.2-0.50.1
Saline control response1.11.53.7-1.2-1.6-0.21.31.9-0.21.0
Bone: connectivity density1.82.95.41.92.00.7-2.0-2.30.9-1.6
Bone: cortical apparent density0.10.10.4-0.6-0.10.1-0.10.00.40.4
Bone: cortical area0.30.51.3-0.3-0.6-1.10.80.6-1.00.4
Bone: cortical porosity1.01.11.9-1.1-1.4-0.61.21.1-0.91.0
Bone: cortical porosity1.61.72.7-1.3-1.6-0.81.41.4-1.21.2
Bone: cortical thickness0.20.31.0-0.2-0.2-1.00.50.0-0.80.1
Bone: cortical thickness0.91.23.80.0-0.5-1.70.50.5-1.90.9
Bone: cortical tissue density0.10.10.5-0.7-0.10.2-0.10.00.40.4
Condit. Reinf. active minus inactive responses1.71.96.1-2.5-1.11.21.51.20.70.6
Condit. Reinf. active-inactive response ratio2.52.69.5-3.1-1.41.31.61.50.50.5
Condit. Reinf. active responses0.91.22.9-1.7-1.00.71.41.10.40.7
Condit. Reinf. inactive responses0.30.41.31.0-0.2-1.20.10.3-0.60.5
Incentive salience index mean0.81.03.0-1.7-0.80.61.50.90.40.3
Condit. Reinf. lever presses0.10.20.7-0.1-0.2-0.20.80.40.2-0.3
Condit. Reinf. active minus inactive responses0.20.31.30.70.0-1.1-0.30.1-0.60.1
Condit. Reinf. active-inactive response ratio0.10.10.40.40.4-0.1-0.4-0.30.3-0.6
Condit. Reinf. active responses0.40.62.30.4-0.1-1.5-0.20.1-1.10.5
Condit. Reinf. inactive responses0.40.71.3-0.6-0.7-1.00.40.6-1.11.0
Condit. Reinf. lever presses0.20.31.10.50.5-1.00.0-0.1-0.80.2
Condit. Reinf. lever reinforcers received0.40.62.20.50.0-1.5-0.30.1-1.10.6
Conditioned reinforcement - actives0.31.12.6-1.0-1.01.20.81.01.6-0.1
Conditioned reinforcement - inactives0.10.20.80.0-0.2-0.10.70.50.40.9
Conditioned locomotion1.21.72.91.61.10.9-1.4-1.11.7-1.3
Patch foraging indifference point 0 sec0.72.13.80.51.41.7-1.5-1.31.9-1.3
Patch foraging indifference point AUC0.00.00.1-0.00.40.1-0.10.10.4-0.1
Delay disc. indifference point, 0s delay0.70.81.61.30.90.4-0.5-0.90.9-1.0
Delay disc. indifference point, 16s delay0.20.31.4-0.60.11.20.2-0.10.5-0.5
Delay disc. indifference point, 2s delay0.70.82.71.60.5-0.5-1.3-0.4-0.1-0.5
Delay disc. indifference point, 24s delay0.30.41.01.00.7-0.8-0.0-0.8-0.4-0.0
Delay disc. indifference point, 4s delay0.30.30.80.50.9-0.1-0.6-0.7-0.20.0
Delay disc. indifference point, 8s delay0.50.91.8-1.1-0.9-0.11.31.2-0.70.8
Indifference point function ln k0.20.72.2-1.5-0.51.30.70.50.5-0.1
Indifference point function log k0.20.72.2-1.5-0.51.30.70.50.5-0.1
Patch foraging total patch changes 0 sec0.72.03.60.31.41.8-1.3-1.21.9-1.4
Patch foraging total patch changes 12 sec0.40.61.10.11.00.7-0.9-0.90.9-0.5
Patch foraging total patch changes 18 sec0.71.63.9-0.11.21.7-0.8-1.02.0-1.1
Patch foraging total patch changes 24 sec0.10.40.9-0.8-0.40.80.60.21.0-0.1
Patch foraging total patch changes 6 sec2.13.65.30.92.31.7-2.1-2.12.0-1.8
Patch foraging time to switch 0 sec0.00.20.70.8-0.0-0.7-0.1-0.2-0.20.1
Patch foraging water rate 0 sec0.10.20.6-0.30.30.8-0.4-0.40.5-0.6
Patch foraging water rate 12 sec0.41.73.4-1.8-1.50.31.81.5-0.60.4
Patch foraging water rate 18 sec0.20.41.3-0.40.40.9-0.4-0.50.1-1.2
Patch foraging water rate 24 sec0.91.24.0-1.30.12.00.70.01.0-1.2
Patch foraging water rate 6 sec1.82.69.8-3.1-1.21.01.91.3-0.40.7
Seeking ratio, delayed vs. immediate footshock1.31.94.52.11.5-1.0-1.8-1.5-0.30.2
Distance traveled before self-admin0.10.20.50.5-0.3-0.50.70.30.0-0.1
Distance traveled after self-admin0.10.20.8-0.20.10.9-0.1-0.00.9-0.1
Extensor digitorum longus weight3.915.720.7-3.2-4.5-3.44.24.3-4.33.3
Bone: elastic displacement0.40.41.3-0.5-0.7-0.31.10.8-0.60.0
Bone: elastic work0.40.61.2-0.7-0.7-0.51.10.7-1.00.1
Bone: endosteal estimation0.10.10.3-0.2-0.3-0.20.60.5-0.40.1
Bone: endosteal perimeter0.30.71.8-0.6-1.0-0.21.11.4-0.30.3
Epididymis fat weight0.20.81.8-1.3-0.90.61.01.1-0.1-0.1
Delta time in closed arm before/after self-admin0.90.81.9-1.4-1.10.61.01.1-0.00.2
Delta time in open arm before/after self-admin0.91.02.7-0.5-1.6-0.70.91.5-0.50.8
Diff in mean of infusions in LGA sessions1.12.04.70.41.91.6-0.9-2.21.1-1.2
Delay discount exponential model param0.00.10.2-0.2-0.4-0.00.10.30.30.0
Extinction: sum of active levers before priming0.20.30.60.10.6-0.7-0.5-0.8-0.60.3
Active lever presses in extinction session 62.82.94.50.61.62.1-1.9-1.72.1-1.4
Bone: final force0.00.00.2-0.4-0.10.10.10.20.2-0.0
Bone: final moment0.00.00.1-0.30.00.0-0.00.1-0.0-0.1
Food consumed during 24 hour testing period0.51.02.8-1.7-1.0-0.30.60.5-1.01.2
Glucose0.30.51.5-1.2-0.1-0.21.10.3-0.40.8
Heart weight0.50.91.6-0.5-1.1-1.00.81.2-1.30.6
Delay discount hyperbolic model param0.10.10.2-0.4-0.50.00.30.30.20.1
Intermittent access intake day 1-15 change0.00.20.80.90.70.0-0.2-0.20.0-0.2
Intermittent access intake escalation0.20.82.11.41.30.2-0.8-0.90.4-0.7
Intermittent access intake escalation 20.50.81.91.41.30.0-1.0-0.90.2-0.6
Intermitt. access day 1 inactive lever presses0.00.40.9-1.0-0.4-0.10.50.3-0.50.9
Intermitt. access day 15 inactive lever presses0.21.21.8-0.8-1.0-1.01.21.1-1.21.3
Intermitt. access escalation Index0.30.92.00.1-0.9-1.40.41.0-1.30.6
Intermittent access day 1 total infusions0.41.22.9-1.7-1.0-0.21.21.0-0.41.2
Intermittent access day 15 total infusions0.00.10.1-0.30.40.2-0.2-0.10.10.3
Intermittent access terminal intake (last 3 days)0.20.31.1-1.10.00.80.10.20.40.3
Intermittent access total infusions0.50.62.4-1.5-0.40.60.80.60.20.6
Intermittent access day 1 locomotion0.20.31.1-1.0-0.40.30.50.50.20.3
Intermittent access day 15 total locomotion0.20.71.30.91.10.6-0.4-0.90.9-0.9
Intermittent access total locomotion0.10.10.20.10.50.2-0.0-0.30.40.1
Intermittent access standard deviation0.00.10.40.00.30.60.10.00.2-0.3
Left kidney weight0.32.13.0-1.7-1.5-1.11.71.3-1.41.2
Right kidney weight0.31.82.4-1.5-1.5-0.91.31.5-1.31.2
Cocaine induced anxiety0.20.61.50.30.51.1-0.5-0.70.8-1.2
Post-drug Anxiety0.70.81.70.80.70.9-0.9-0.80.7-1.3
Baseline Anxiety0.10.20.4-0.3-0.3-0.50.10.5-0.70.4
Tail length0.20.91.5-0.2-1.1-1.21.00.9-1.20.6
Length with tail0.21.11.6-1.2-1.3-0.51.11.3-1.10.7
Length without tail0.10.30.9-0.8-0.40.9-0.10.30.4-0.6
Times rat made contact with spout0.30.41.50.20.9-0.1-0.6-1.2-0.20.1
Lifetime Intake0.70.92.9-1.7-0.70.71.00.80.30.7
Liver weight, left0.20.30.8-0.5-0.20.80.00.20.9-0.5
Liver weight, right0.40.72.0-0.20.41.0-0.7-0.21.4-1.0
Locomotor activity0.10.10.3-0.10.5-0.0-0.4-0.2-0.10.4
Locomotor testing distance0.10.41.0-0.5-0.0-0.5-0.00.1-1.01.0
Locomotor testing rearing0.20.61.3-0.71.20.1-0.6-1.0-0.60.6
Locomotion in novel chamber4.76.312.53.52.9-0.2-3.5-3.01.0-1.0
Locomotion in novel chamber post-restriction0.30.92.70.3-0.1-1.50.3-0.0-1.01.6
Fecal boli incidents, locomotor time 10.30.72.7-0.5-0.7-0.80.50.70.11.6
Change in fecal boli incidents, locomotor task0.20.31.0-0.40.3-0.11.00.0-0.60.5
Time >=10cm from walls, locomotor time 12.12.64.41.32.11.1-1.5-1.81.6-1.6
Bouts of movement, locomotor time 10.40.51.10.70.9-0.1-1.0-0.90.1-0.7
Total resting periods, locomotor time 10.20.20.60.30.60.0-0.8-0.50.1-0.4
Rest time, locomotor task time 10.40.71.60.2-0.9-0.90.30.8-1.30.8
Distance moved, locomotor task time 10.10.20.6-0.40.40.7-0.0-0.40.3-0.6
Vertical activity count, locomotor time 10.10.61.30.10.80.8-0.7-0.80.9-1.1
Time >=10cm from walls, locomotor time 20.61.74.1-1.4-1.6-0.32.01.5-0.70.5
Bouts of movement, locomotor time 20.20.81.61.31.00.2-0.3-1.20.4-1.2
Total resting periods, locomotor time 20.20.81.81.31.00.2-0.5-1.30.4-1.1
Rest time, locomotor task time 20.60.91.91.40.5-1.3-1.2-0.2-0.90.6
Distance moved, locomotor task time 20.50.71.8-0.7-0.51.30.70.30.6-1.2
Vertical activity count, locomotor time 20.10.20.7-0.0-0.20.40.2-0.30.3-0.9
Light reinforcement 10.20.94.1-2.0-0.80.50.90.7-0.30.5
Light reinforcement 20.10.20.9-0.1-0.1-0.60.20.2-0.90.4
Bone: marrow area0.00.10.2-0.1-0.2-0.20.50.4-0.40.1
Bone: maximum diameter0.10.10.40.1-0.1-0.70.30.2-0.40.1
Bone: maximum force0.10.20.6-0.3-0.00.60.1-0.00.5-0.7
Bone: maximum moment0.10.10.5-0.10.10.4-0.0-0.10.3-0.7
Mean time between licks in bursts0.21.32.9-0.30.81.7-0.8-1.01.4-1.4
Mean num. licks in bursts0.61.74.81.30.2-2.2-0.2-0.4-1.91.2
Cd content in liver0.40.41.0-0.40.21.0-0.6-0.20.9-0.7
Co content in liver3.33.98.8-3.0-2.00.82.62.4-0.11.1
Cu content in liver2.83.34.91.11.91.7-2.2-2.01.7-1.9
Fe content in liver0.50.62.81.7-0.2-0.9-0.60.0-0.1-0.7
K content in liver0.70.71.71.31.3-0.1-0.3-1.00.7-0.3
Mg content in liver0.50.61.40.21.00.8-0.4-0.71.2-0.5
Mn content in liver0.30.30.60.60.6-0.8-0.2-0.7-0.40.4
Na content in liver0.30.30.70.80.6-0.10.1-0.70.1-0.6
Rb content in liver0.20.20.5-0.3-0.50.70.30.30.7-0.4
Se content in liver0.20.30.80.7-0.2-0.90.30.2-0.50.4
Sr content in liver0.90.82.20.40.0-1.50.10.4-1.41.2
Zn content in liver23.026.843.14.46.63.8-5.4-5.84.8-4.9
Bone: minimum diameter1.02.03.0-1.7-1.7-0.51.61.6-1.20.9
Time in familiar zone, hab. session 10.10.10.3-0.2-0.60.20.20.30.40.1
Time in novel zone, hab. session 10.20.20.40.60.2-0.6-0.40.2-0.6-0.0
Total zone transitions, hab. session 12.33.37.4-2.7-2.30.82.11.90.21.2
Total locomotion distance, hab. session 10.40.61.3-1.1-0.61.10.80.50.8-0.1
Locomotion velocity, hab. session 10.40.51.3-1.1-0.31.00.80.30.7-0.0
Time in familiar zone, hab. session 21.11.24.21.00.3-2.1-0.4-0.2-1.51.0
Time in novel zone, hab. session 20.60.72.2-0.60.11.5-0.1-0.11.4-0.6
Total zone transitions, hab. session 21.31.75.0-2.2-1.41.21.31.10.70.4
Total locomotion distance, hab. session 20.20.31.1-1.1-0.20.50.50.20.20.1
Locomotion velocity, hab. session 20.20.20.9-0.9-0.10.70.40.00.4-0.0
Novel to familiar place preference ratio0.10.20.5-0.50.30.4-0.7-0.20.10.3
Novelty place preference0.20.20.6-0.50.40.4-0.8-0.3-0.10.4
Time in novel zone, NPP test0.20.20.6-0.40.40.2-0.8-0.3-0.20.4
Total zone transitions, NPP test1.21.86.2-2.5-1.40.81.51.00.30.7
Total locomotion distance, NPP test0.30.41.0-0.80.31.00.1-0.30.8-0.6
Locomotion velocity, NPP test0.30.40.9-0.90.30.90.1-0.40.7-0.5
Intraocular pressure0.20.30.90.7-0.3-0.9-0.00.4-0.7-0.2
Delta distance traveled before/after self-admin0.60.62.4-1.00.21.5-0.5-0.00.9-0.3
Delta ambulatory time before/after self-admin0.40.72.4-0.80.41.6-0.4-0.40.9-0.5
Parametrial fat weight0.40.92.30.71.11.1-0.8-0.40.9-1.5
Pavlov. Cond. lever latency0.60.81.1-1.0-1.0-0.40.71.0-0.91.0
Pavlov. Cond. magazine entry latency0.30.41.0-0.4-0.8-0.21.00.9-0.20.4
Pavlov. Cond. change in total contacts0.20.31.1-0.40.10.70.4-0.11.0-0.1
Pavlov. Cond. index score0.20.20.40.70.60.0-0.1-0.50.4-0.5
Pavlov. Cond. latency score0.30.40.80.90.80.2-0.4-0.80.6-0.7
Pavlov. Cond. lever contacts0.50.61.00.90.90.3-0.4-0.90.8-1.0
Pavlov. Cond. magazine entry number0.40.61.11.01.0-0.1-1.1-0.80.0-0.4
Pavlov. Cond. intertrial magazine entries0.30.40.80.40.60.8-0.5-0.10.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.60.70.0-0.2-0.60.3-0.3
Pavlov. Cond. response bias0.20.20.4-0.3-0.40.50.60.40.6-0.4
Pavlov. Cond. lever latency0.30.51.21.00.6-0.3-1.1-0.90.20.2
Pavlov. Cond. magazine entry latency0.10.10.20.50.1-0.40.30.4-0.1-0.1
Pavlov. Cond. change in total contacts0.10.20.60.00.50.5-0.3-0.20.3-0.7
Pavlov. Cond. index score0.10.10.30.60.2-0.30.20.2-0.2-0.6
Pavlov. Cond. latency score0.10.20.70.70.50.1-0.1-0.20.3-0.9
Pavlov. Cond. lever contacts0.30.51.1-0.8-0.7-0.11.01.1-0.5-0.1
Pavlov. Cond. magazine entry number0.10.10.4-0.6-0.10.4-0.2-0.10.10.3
Pavlov. Cond. intertrial magazine entries0.20.40.90.40.3-0.9-0.8-0.6-0.90.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.70.3-0.30.10.1-0.1-0.6
Pavlov. Cond. response bias0.81.12.2-0.8-1.1-0.61.41.5-0.90.4
Time in closed arm before self-admin0.40.82.1-0.00.61.4-0.0-0.51.5-0.8
Time in closed arm after self-admin1.72.04.60.11.22.2-0.8-1.21.8-1.6
Time in open arm before self-admin0.50.61.70.00.4-1.2-0.6-0.3-1.30.7
Time in open arm after self-admin1.01.12.1-0.3-1.2-1.50.21.1-1.21.0
Bone: periosteal estimation0.30.71.2-0.5-0.7-0.91.00.8-1.10.5
Bone: periosteal perimeter0.71.42.1-0.7-1.3-1.21.51.4-1.21.0
Bone: post-yield work1.11.83.90.60.81.9-0.7-0.62.0-1.8
Progressive ratio test 1 active lever presses1.52.67.5-2.7-1.70.41.61.7-0.71.4
Progressive ratio test 1 breakpoint1.32.27.2-2.7-1.50.61.41.5-0.51.2
Progressive ratio test 1 inactive lever presses0.51.22.3-0.8-0.6-1.01.40.8-1.21.5
Progressive ratio test 2 active lever presses1.31.83.3-1.7-1.4-0.51.51.8-0.91.2
Progressive ratio test 2 breakpoint1.11.52.4-1.5-1.2-0.51.31.6-0.91.2
Progressive ratio test 2 inactive lever presses0.30.81.7-0.9-1.1-0.40.71.3-0.31.2
Incentive Sensitization - Responses0.10.10.50.70.1-0.3-0.10.40.4-0.3
Incentive Sensitization - Breakpoint0.10.20.70.80.2-0.5-0.20.30.1-0.2
Sum of active levers in priming session hrs 5-62.01.95.01.52.0-0.1-1.2-2.20.2-0.8
Progressive ratio0.61.75.10.5-0.5-2.3-0.10.3-1.81.7
Food seeking constrained by brief footshock0.10.10.5-0.7-0.10.20.10.0-0.4-0.2
Seeking ratio, punishment vs. effort0.51.13.8-0.90.42.00.1-0.31.1-1.3
Retroperitoneal fat weight0.10.41.5-0.3-0.3-0.70.60.7-1.20.0
Reaction time number correct0.10.20.8-0.3-0.1-0.40.20.0-0.90.7
Reaction time mean minus median0.10.62.11.1-0.1-1.4-0.10.3-0.50.6
Reaction time mean minus median AUC0.10.41.31.10.1-1.2-0.3-0.1-0.50.3
Reaction time num false alarms0.61.02.7-0.8-1.7-0.20.61.4-0.41.1
Reaction time num false alarms AUC0.81.94.5-0.9-2.1-0.61.22.0-0.71.2
Reaction time trials correct on left0.10.20.8-0.3-0.1-0.40.20.0-0.90.7
Reaction time trials on left0.10.20.9-0.2-0.0-0.50.2-0.0-0.90.7
Reaction time mean0.61.34.50.9-0.2-2.10.20.4-1.61.2
Reaction time mean AUC0.71.65.00.6-0.5-2.20.40.6-1.81.5
Median of all reaction times0.91.44.10.5-0.4-2.00.40.5-1.81.3
Reaction time omissions0.61.04.02.00.2-1.4-0.8-0.2-0.8-0.1
Reaction time false alarm rate0.50.72.2-0.4-1.5-0.20.51.3-0.10.6
Reaction time premature initiation rate1.52.34.3-1.5-2.0-0.61.72.1-0.91.2
Reaction time premature initiations1.13.35.0-1.7-2.2-1.02.02.2-1.51.7
Std. dev. reaction times0.20.72.51.60.2-1.4-0.4-0.1-0.40.2
Reaction time trials completed0.10.20.9-0.2-0.0-0.50.2-0.0-0.90.7
Reaction time trials AUC0.10.20.7-0.3-0.1-0.30.20.0-0.80.6
Run reversals in cocaine runway, females0.10.20.4-0.00.6-0.1-0.1-0.6-0.10.5
Run reversals in cocaine runway, males0.50.61.8-1.0-0.2-0.20.5-0.0-0.91.4
Latency to leave start box in cocaine runway0.60.81.30.31.11.1-0.3-1.11.0-0.8
Latency to leave start box in cocaine runway, F0.60.82.2-0.20.41.50.2-0.31.2-1.2
Latency to leave start box in cocaine runway, M1.31.22.91.11.7-0.2-1.2-1.70.30.2
Std. dev. time between licks in bursts1.83.310.8-1.20.83.3-1.1-1.02.4-1.7
Total sessions with >9 infusions1.41.74.8-2.2-0.91.61.20.81.20.6
Short access day 1 total inactive lever presses0.40.82.0-1.30.01.40.9-0.21.20.1
Short access day 10 total inactive lever presses0.00.30.80.90.60.10.1-0.60.5-0.3
Short access day 1 total infusions0.71.43.6-1.5-0.61.90.80.51.7-0.3
Short access day 10 total infusions0.81.23.5-1.9-0.80.51.70.80.10.8
Short access total infusions1.01.44.4-2.1-0.81.11.20.80.60.8
Short access day 1 locomotion1.32.27.0-1.50.12.60.4-0.22.2-1.1
Short access day 10 total locomotion0.10.40.8-0.10.80.8-0.5-0.90.8-0.4
Short access total locomotion0.50.71.6-0.40.91.3-0.4-0.91.3-0.5
One hour access (0.3 mA shock)0.00.00.10.10.3-0.1-0.20.00.00.2
Compulsive drug intake0.30.51.40.80.5-1.2-0.4-0.3-0.70.1
One hour access (shock baseline)0.10.30.7-0.7-0.40.00.80.6-0.30.5
Social response proportion0.10.20.50.70.1-0.5-0.20.40.20.2
Social responses0.50.71.30.91.0-0.1-1.1-1.1-0.1-0.5
Social time1.01.54.62.21.2-0.2-1.7-1.00.6-0.8
Soleus weight1.03.14.9-1.4-1.9-1.32.22.1-1.71.5
Bone: stiffness0.00.10.3-0.6-0.10.10.1-0.00.2-0.1
Tibialis anterior weight4.716.125.8-3.1-4.4-3.64.33.8-5.13.5
Time to tail flick, vehicle, before self-admin0.10.10.30.3-0.2-0.20.20.30.60.4
Time to tail flick, vehicle, after self-admin0.20.41.71.3-0.2-0.7-0.20.2-0.0-0.8
Time to tail flick, test, before self-admin0.40.51.71.30.4-0.7-1.0-0.3-0.10.3
Time to tail flick, test, after self-admin0.20.20.60.30.20.5-0.2-0.00.7-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.7-0.0-0.10.3-0.0-0.10.1-0.8
Delta time to tail flick, test, before/after SA0.40.51.0-1.0-0.40.90.90.40.4-0.7
Tibia length0.82.15.8-0.1-1.3-2.20.81.0-2.41.0
Ambulatory time before self-admin0.10.20.50.4-0.3-0.50.70.30.10.2
Ambulatory time after self-admin0.40.62.10.10.11.3-0.2-0.01.5-0.5
Bone: tissue strength0.60.61.7-0.30.21.3-0.4-0.10.7-1.2
Total heroin consumption0.30.40.80.90.7-0.3-0.7-0.80.0-0.3
Bone: trabecular number0.30.51.81.40.4-0.3-0.6-0.70.3-0.6
Bone: trabecular spacing0.30.41.20.41.10.0-0.7-0.8-0.2-0.4
Bone: trabecular thickness0.40.61.3-0.5-0.9-0.70.70.5-0.51.1
Bone: trabecular tissue density0.61.01.7-0.8-1.1-0.71.31.0-0.51.3
Water consumed over 24 hours0.10.20.7-0.8-0.3-0.00.50.0-0.00.4
Number of responses in last shaping day2.32.96.0-2.1-2.20.12.52.0-0.31.1