Hub : Genes

C1qc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression C1qc 0.35 0.15 2.1e-11 0.2 0.19 0.21 0.2 8.8e-09 1.4e-08 4.1e-09 7.5e-09
2 pVTA gene expression C1qc 0.21 0.1 0.0e+00 0.26 0.25 0.26 0.26 1.4e-20 4.0e-20 1.1e-20 1.5e-20
3 BLA gene expression C1qc 0.25 0.13 5.8e-11 0.2 0.19 0.2 0.2 1.2e-10 3.8e-10 1.1e-10 6.0e-11
4 PL gene expression C1qc 0.17 0.07 0.0e+00 0.25 0.25 0.25 0.25 3.0e-27 3.2e-27 1.7e-27 3.3e-27
5 RMTg gene expression C1qc 0.1 0.07 6.1e-03 0.06 0.04 0.06 0.04 1.2e-02 3.1e-02 1.1e-02 3.3e-02
6 Brain gene expression C1qc 0.36 0.14 0.0e+00 0.32 0.3 0.32 0.33 4.7e-30 7.2e-29 8.0e-31 6.6e-32
7 Adipose mRNA stability C1qc 0.02 0.02 5.1e-03 0.01 0 0 0 2.8e-02 1.0e-01 3.1e-01 1.1e-01
8 OFC gene expression C1qc 0.29 0.16 2.3e-05 0.22 0.16 0.19 0.21 7.5e-06 1.4e-04 2.5e-05 9.1e-06
9 NAcc gene expression C1qc 0.19 0.11 0.0e+00 0.17 0.18 0.17 0.18 2.0e-24 5.3e-26 1.7e-25 5.7e-26
10 LHb gene expression C1qc 0.33 0.21 1.3e-06 0.24 0.29 0.3 0.27 2.6e-06 1.0e-07 9.7e-08 4.0e-07
11 IL gene expression C1qc 0.21 0.12 1.5e-05 0.14 0.18 0.2 0.18 2.5e-04 4.1e-05 1.9e-05 4.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.42.54.31.61.8-1.51.71.6-1.61.51.0-1.71.02.1
Area under the delay curve0.10.20.70.00.20.10.20.30.30.60.7-0.1-0.9-0.3
BMI with tail1.13.710.41.21.6-1.61.82.5-1.62.83.2-1.80.70.7
BMI without tail0.84.27.32.02.1-2.02.12.5-1.82.72.6-1.91.20.6
Body weight2.29.819.73.12.8-2.72.73.6-2.84.04.4-1.93.41.9
Weight adjusted by age0.10.40.6-0.6-0.70.7-0.7-0.50.8-0.30.00.8-0.4-0.6
Bone surface1.12.23.11.51.6-1.41.51.8-1.41.71.1-1.41.31.6
Bone volume1.12.23.01.61.7-1.41.51.6-1.41.50.9-1.31.41.7
Breakpoint value in progressive ratio session0.10.10.40.30.3-0.50.50.0-0.4-0.1-0.3-0.5-0.30.6
Number of licking bursts0.20.51.1-0.7-0.70.7-0.7-0.80.7-0.8-0.50.6-1.1-0.3
Context. condit. distance diff. score1.82.23.01.51.7-1.71.71.5-1.71.31.2-1.70.61.1
Locomotion velocity, session 11.21.42.31.21.5-1.31.40.9-1.20.70.9-1.5-0.41.3
Locomotion distance, session 10.70.91.90.71.0-0.91.00.3-1.1-0.10.0-1.4-1.31.2
Locomotion velocity, session 22.12.64.6-1.5-1.61.6-1.6-1.91.4-2.1-1.71.5-1.5-1.0
Locomotion distance, session 21.11.62.31.41.5-1.51.41.2-1.50.90.9-1.40.41.5
Locomotion velocity, session 30.40.52.1-0.4-0.00.2-0.0-0.60.3-0.7-0.7-0.6-1.4-1.0
Locomotion distance, session 33.03.46.61.92.2-2.22.21.5-2.31.01.0-2.60.01.8
Stereotopy head waving bouts, day 31.01.22.4-1.0-1.11.3-1.2-1.01.4-0.6-0.91.3-0.3-1.6
Stereotopy head waving duration, day 32.42.95.0-1.6-1.82.0-1.9-1.62.0-1.1-1.32.1-0.3-2.2
Locomotion velocity, session 72.42.73.81.91.9-1.91.91.8-1.71.91.1-1.80.50.9
Locomotion distance, session 70.40.60.90.80.8-1.00.80.8-0.81.00.4-0.8-0.00.0
Stereotopy head waving bouts, day 70.10.10.6-0.1-0.10.1-0.20.00.10.10.20.20.8-0.6
Stereotopy head waving duration, day 70.10.11.0-0.1-0.10.3-0.3-0.00.3-0.10.30.51.0-0.2
Locomotion velocity, session 80.20.20.50.30.6-0.50.60.4-0.50.30.6-0.7-0.20.6
Locomotion distance, session 83.24.67.42.12.5-2.42.42.1-2.51.71.7-2.70.72.0
Degree of sensitization distance3.23.56.2-1.8-2.12.1-2.1-1.52.3-1.0-1.12.5-0.6-2.2
Degree of sensitization stereotypy0.30.31.50.50.4-0.40.30.6-0.40.60.8-0.21.2-0.1
Conditioned locomotion2.32.77.8-1.4-1.51.4-1.4-1.61.6-1.5-1.71.1-2.8-1.7
Cocaine response after cond. corrected3.85.76.7-2.5-2.62.5-2.6-2.62.5-2.5-2.22.3-2.5-1.3
Cocaine response after cond. not corrected3.14.56.9-2.1-2.12.1-2.1-2.52.0-2.6-2.41.9-2.2-1.0
Cocaine response before conditioning1.41.72.71.61.5-1.41.41.0-1.60.70.6-1.31.51.3
Saline control response0.20.30.8-0.20.1-0.20.2-0.5-0.1-0.6-0.6-0.6-0.7-0.9
Bone: connectivity density0.91.43.11.21.2-1.21.21.2-1.30.90.3-1.21.01.8
Bone: cortical apparent density0.10.10.5-0.1-0.10.1-0.2-0.10.1-0.3-0.70.1-0.40.4
Bone: cortical area3.76.17.72.82.7-2.52.72.5-2.62.42.1-2.42.12.3
Bone: cortical porosity1.31.42.5-1.1-1.11.3-1.2-1.51.1-1.6-1.51.1-0.2-0.8
Bone: cortical porosity1.71.82.5-1.3-1.41.5-1.5-1.61.4-1.5-1.41.6-0.4-0.9
Bone: cortical thickness2.44.05.72.02.2-2.02.21.9-2.21.81.3-2.21.32.4
Bone: cortical thickness0.91.13.20.91.3-1.21.40.7-1.40.4-0.1-1.8-0.20.9
Bone: cortical tissue density0.20.30.8-0.4-0.40.4-0.5-0.40.4-0.5-0.90.4-0.60.1
Condit. Reinf. active minus inactive responses1.61.83.5-1.2-1.41.6-1.6-1.61.6-1.5-0.71.9-0.2-0.5
Condit. Reinf. active-inactive response ratio2.02.24.6-1.4-1.61.8-1.7-1.51.8-1.3-0.62.1-0.0-0.8
Condit. Reinf. active responses0.40.61.7-0.2-0.60.7-0.8-0.90.8-0.9-0.51.30.3-0.1
Condit. Reinf. inactive responses0.50.62.01.40.9-1.00.80.6-0.90.40.1-0.50.60.6
Incentive salience index mean0.50.71.6-0.3-0.70.8-0.8-1.10.9-1.1-0.61.30.3-0.2
Condit. Reinf. lever presses0.30.41.51.20.7-0.60.60.1-0.6-0.0-0.1-0.11.20.4
Condit. Reinf. active minus inactive responses0.60.91.70.71.0-1.01.01.1-1.01.01.3-1.10.40.7
Condit. Reinf. active-inactive response ratio0.71.12.4-1.5-1.21.3-1.2-1.11.2-0.9-0.51.0-0.8-0.7
Condit. Reinf. active responses4.76.78.22.72.8-2.92.82.8-2.82.62.6-2.71.61.8
Condit. Reinf. inactive responses8.312.317.94.23.8-4.13.83.8-3.83.53.0-3.22.72.1
Condit. Reinf. lever presses3.85.67.92.62.7-2.72.62.2-2.81.81.7-2.51.32.3
Condit. Reinf. lever reinforcers received4.66.48.12.72.8-2.82.82.8-2.72.52.5-2.51.61.9
Conditioned reinforcement - actives0.41.65.01.20.9-0.90.81.3-0.71.41.7-0.11.32.2
Conditioned reinforcement - inactives0.61.54.31.21.0-1.00.91.2-0.91.41.6-0.60.92.1
Conditioned locomotion1.31.94.81.41.3-1.41.21.3-1.11.31.8-0.81.12.2
Patch foraging indifference point 0 sec0.82.34.71.41.7-1.81.81.4-2.21.10.4-2.01.21.0
Patch foraging indifference point AUC0.92.13.21.71.6-1.71.81.4-1.71.01.3-1.60.81.2
Delay disc. indifference point, 0s delay0.60.71.20.60.9-0.71.01.1-0.71.11.1-1.10.30.0
Delay disc. indifference point, 16s delay0.10.10.60.20.10.00.10.30.20.40.40.1-0.80.4
Delay disc. indifference point, 2s delay0.20.31.3-0.10.10.10.10.50.20.80.9-0.00.2-1.1
Delay disc. indifference point, 24s delay0.30.51.2-0.6-0.80.8-0.9-0.70.8-0.6-0.41.1-0.3-0.6
Delay disc. indifference point, 4s delay0.30.32.00.00.00.2-0.00.20.40.60.60.1-1.4-0.2
Delay disc. indifference point, 8s delay0.10.20.70.10.3-0.10.30.40.10.60.8-0.3-0.8-0.2
Indifference point function ln k0.82.33.2-1.6-1.61.6-1.7-1.41.8-1.0-1.41.7-1.3-1.2
Indifference point function log k0.82.33.2-1.6-1.61.6-1.7-1.41.8-1.0-1.41.7-1.3-1.2
Patch foraging total patch changes 0 sec0.82.34.61.41.7-1.81.81.3-2.21.00.4-2.01.11.1
Patch foraging total patch changes 12 sec2.33.05.82.12.0-2.12.11.3-2.40.90.9-2.01.21.2
Patch foraging total patch changes 18 sec1.63.76.22.42.2-2.42.51.7-2.51.40.6-2.40.61.1
Patch foraging total patch changes 24 sec1.13.77.62.02.3-2.32.51.6-2.50.91.1-2.70.81.3
Patch foraging total patch changes 6 sec2.74.58.42.22.3-2.52.61.9-2.91.50.8-2.71.11.6
Patch foraging time to switch 0 sec0.20.61.9-0.6-0.60.6-0.7-1.00.3-1.0-1.40.70.6-0.2
Patch foraging water rate 0 sec0.10.32.7-0.4-0.10.20.1-0.20.3-0.1-0.2-0.4-1.7-0.5
Patch foraging water rate 12 sec0.10.62.70.10.6-0.50.80.4-0.50.20.3-1.2-1.60.5
Patch foraging water rate 18 sec0.61.32.21.41.1-0.91.11.4-0.81.41.5-0.60.41.0
Patch foraging water rate 24 sec0.50.81.3-0.7-0.80.9-0.8-0.61.2-0.5-0.60.9-1.2-1.1
Patch foraging water rate 6 sec0.50.74.1-0.8-0.60.6-0.4-0.70.9-0.6-0.50.1-2.0-0.8
Seeking ratio, delayed vs. immediate footshock1.42.13.91.21.6-1.31.71.5-1.51.71.5-2.00.7-0.1
Distance traveled before self-admin1.32.83.41.81.8-1.81.81.7-1.81.81.8-1.71.01.0
Distance traveled after self-admin2.13.64.62.12.1-2.12.11.9-2.21.51.5-2.11.11.9
Extensor digitorum longus weight0.83.14.41.51.9-1.82.01.8-1.91.51.7-2.10.81.9
Bone: elastic displacement0.30.41.20.40.5-0.40.50.1-0.7-0.0-1.1-0.80.20.8
Bone: elastic work0.91.12.21.01.3-1.01.31.0-1.11.0-0.1-1.50.61.2
Bone: endosteal estimation1.02.46.11.71.3-1.21.21.7-1.01.82.2-0.42.50.6
Bone: endosteal perimeter1.02.34.31.71.5-1.31.41.7-1.21.72.1-0.92.10.5
Epididymis fat weight0.10.71.2-1.0-1.00.9-1.0-0.51.0-0.2-0.31.1-0.1-1.1
Delta time in closed arm before/after self-admin0.30.31.1-0.2-0.50.4-0.7-0.30.4-0.3-0.11.00.80.1
Delta time in open arm before/after self-admin0.20.20.5-0.3-0.40.5-0.4-0.30.5-0.1-0.40.50.7-0.5
Diff in mean of infusions in LGA sessions0.10.20.90.30.1-0.10.1-0.50.1-0.5-1.00.0-0.30.0
Delay discount exponential model param0.10.20.80.10.0-0.30.0-0.2-0.4-0.5-0.7-0.10.90.4
Extinction: sum of active levers before priming0.40.63.00.20.2-0.40.30.9-0.41.20.80.11.70.3
Active lever presses in extinction session 60.20.20.4-0.6-0.50.4-0.3-0.60.3-0.4-0.40.50.10.5
Bone: final force2.64.25.82.32.4-2.22.42.1-2.21.91.5-2.21.31.8
Bone: final moment3.35.26.92.52.6-2.42.62.4-2.42.21.8-2.41.42.2
Food consumed during 24 hour testing period0.10.20.7-0.0-0.10.3-0.3-0.50.6-0.4-0.10.3-0.2-0.9
Glucose0.30.41.0-0.7-0.70.7-0.7-0.20.90.10.41.00.2-0.7
Heart weight0.10.21.3-0.2-0.10.2-0.10.00.20.30.30.10.1-1.1
Delay discount hyperbolic model param0.20.20.90.10.0-0.30.0-0.2-0.4-0.5-0.7-0.10.90.5
Intermittent access intake day 1-15 change0.31.63.01.41.2-1.21.11.5-0.91.71.5-0.70.91.5
Intermittent access intake escalation0.42.13.61.51.3-1.41.31.7-1.11.91.7-0.81.11.7
Intermittent access intake escalation 20.20.40.90.90.6-0.60.50.6-0.40.80.5-0.20.10.9
Intermitt. access day 1 inactive lever presses0.33.85.52.21.8-1.81.82.1-1.82.22.3-1.22.21.9
Intermitt. access day 15 inactive lever presses0.10.61.10.70.7-0.50.70.9-0.51.01.0-0.31.10.6
Intermitt. access escalation Index1.03.14.51.21.8-1.91.91.8-1.81.51.7-2.11.12.1
Intermittent access day 1 total infusions1.02.93.92.01.8-1.71.71.7-1.71.71.9-1.41.21.9
Intermittent access day 15 total infusions1.94.67.02.42.1-2.12.02.3-1.82.42.5-1.51.62.6
Intermittent access terminal intake (last 3 days)2.13.76.02.32.0-1.91.81.9-1.62.02.0-1.31.52.4
Intermittent access total infusions2.83.35.72.01.8-1.71.61.9-1.52.02.2-1.11.52.4
Intermittent access day 1 locomotion0.71.32.21.21.2-1.21.21.0-1.01.01.5-1.10.31.3
Intermittent access day 15 total locomotion0.10.51.21.10.8-0.90.70.1-0.7-0.10.3-0.4-0.31.1
Intermittent access total locomotion2.83.45.62.12.0-2.11.91.6-1.91.41.8-1.61.02.4
Intermittent access standard deviation0.84.28.22.11.8-1.81.72.4-1.52.92.8-0.91.72.1
Left kidney weight2.318.630.24.84.2-4.13.94.7-4.04.84.7-2.75.53.3
Right kidney weight0.96.016.22.92.2-2.12.02.6-2.12.72.6-0.84.01.3
Cocaine induced anxiety0.10.20.4-0.2-0.30.4-0.4-0.20.4-0.4-0.20.70.60.1
Post-drug Anxiety0.30.30.6-0.5-0.40.6-0.5-0.50.6-0.7-0.80.5-0.3-0.6
Baseline Anxiety0.10.10.6-0.3-0.10.20.0-0.10.10.0-0.1-0.2-0.8-0.7
Tail length0.42.17.82.21.4-1.21.01.3-1.01.51.0-0.12.80.6
Length with tail1.15.012.32.82.1-1.91.82.2-1.92.42.4-0.83.51.7
Length without tail0.31.44.31.00.7-0.60.61.1-0.81.31.9-0.22.11.1
Times rat made contact with spout0.80.92.5-0.4-0.40.5-0.4-1.30.4-1.5-1.60.0-1.3-0.6
Lifetime Intake2.32.85.81.81.6-1.51.41.7-1.31.82.1-0.91.52.4
Liver weight, left3.35.615.22.62.1-1.92.02.6-2.12.82.3-1.13.91.6
Liver weight, right1.01.78.41.40.8-1.00.81.3-1.01.31.3-0.02.90.1
Locomotor activity6.19.613.83.03.1-3.23.13.4-2.93.23.7-2.82.62.7
Locomotor testing distance2.35.78.12.42.5-2.52.42.7-2.22.52.8-2.22.01.8
Locomotor testing rearing1.86.57.92.62.7-2.82.62.7-2.62.62.5-2.52.51.7
Locomotion in novel chamber3.64.910.61.42.3-2.32.52.4-2.11.91.9-3.3-0.12.6
Locomotion in novel chamber post-restriction0.10.20.80.50.4-0.30.30.5-0.20.80.4-0.20.30.9
Fecal boli incidents, locomotor time 11.64.27.61.91.7-1.91.62.1-2.21.92.1-1.32.82.6
Change in fecal boli incidents, locomotor task5.15.47.2-2.4-2.52.5-2.4-2.32.7-1.9-1.72.3-2.6-2.2
Time >=10cm from walls, locomotor time 10.20.30.80.60.6-0.40.50.5-0.40.60.5-0.40.9-0.1
Bouts of movement, locomotor time 10.60.71.4-1.1-0.80.7-0.8-1.00.6-0.9-0.50.3-1.2-1.1
Total resting periods, locomotor time 10.70.81.4-1.2-0.90.8-0.8-1.00.7-0.9-0.60.4-1.0-1.1
Rest time, locomotor task time 12.84.45.9-2.4-2.42.3-2.3-2.12.4-1.9-1.92.2-0.8-2.1
Distance moved, locomotor task time 10.72.02.71.31.6-1.41.61.5-1.41.51.4-1.60.61.2
Vertical activity count, locomotor time 10.64.25.62.02.3-2.12.32.1-2.11.91.7-2.41.51.8
Time >=10cm from walls, locomotor time 20.00.00.3-0.3-0.10.0-0.0-0.0-0.20.10.3-0.1-0.0-0.5
Bouts of movement, locomotor time 20.72.23.3-1.7-1.51.5-1.5-1.51.5-1.3-1.31.2-1.2-1.8
Total resting periods, locomotor time 20.93.75.6-2.2-2.02.0-2.0-1.92.0-1.7-1.71.6-1.5-2.4
Rest time, locomotor task time 22.03.54.2-2.0-2.02.0-2.0-2.02.0-2.1-1.91.8-1.4-1.2
Distance moved, locomotor task time 21.62.13.21.51.5-1.41.51.6-1.21.61.6-1.31.80.5
Vertical activity count, locomotor time 21.94.57.62.12.2-2.02.22.3-2.02.21.9-2.02.81.3
Light reinforcement 10.20.81.31.00.9-1.01.10.9-1.00.70.9-1.10.30.6
Light reinforcement 20.10.30.60.30.5-0.50.60.8-0.50.70.6-0.8-0.10.3
Bone: marrow area1.02.46.11.71.3-1.21.21.7-1.01.82.2-0.42.50.6
Bone: maximum diameter2.85.67.42.72.4-2.32.42.6-2.22.72.7-1.82.21.5
Bone: maximum force3.06.07.42.72.7-2.52.62.7-2.32.72.2-2.32.02.0
Bone: maximum moment3.87.28.72.92.9-2.72.82.9-2.52.92.5-2.52.22.3
Mean time between licks in bursts0.00.10.70.00.0-0.20.10.3-0.30.40.8-0.1-0.30.6
Mean num. licks in bursts0.00.10.30.30.3-0.20.2-0.2-0.3-0.4-0.6-0.40.2-0.2
Cd content in liver7.48.311.42.72.9-3.03.03.4-3.03.02.9-2.82.22.5
Co content in liver1.31.53.31.81.3-1.61.40.9-1.80.4-0.1-1.30.80.6
Cu content in liver0.70.81.6-0.7-0.80.7-0.8-0.80.9-0.8-1.10.7-1.1-1.3
Fe content in liver0.10.20.70.30.3-0.20.20.30.00.30.8-0.10.20.8
K content in liver0.10.10.2-0.3-0.30.3-0.3-0.20.5-0.4-0.50.3-0.4-0.2
Mg content in liver0.10.10.2-0.3-0.30.3-0.3-0.20.5-0.4-0.40.4-0.5-0.4
Mn content in liver0.50.61.60.50.3-0.40.31.0-0.51.01.30.10.91.0
Na content in liver1.21.32.31.51.4-1.31.21.1-1.00.91.3-0.90.71.1
Rb content in liver0.50.61.5-0.7-0.91.0-0.9-0.70.9-0.7-0.31.20.2-0.1
Se content in liver1.51.83.0-1.5-1.61.5-1.6-1.21.6-1.2-0.41.7-0.9-0.5
Sr content in liver1.31.21.71.11.2-1.31.21.0-1.20.80.9-1.30.31.1
Zn content in liver0.10.20.70.40.5-0.50.40.3-0.2-0.10.1-0.5-0.80.1
Bone: minimum diameter0.91.75.91.61.1-1.01.01.2-1.01.31.3-0.22.40.8
Time in familiar zone, hab. session 10.20.20.70.10.3-0.40.40.3-0.60.2-0.5-0.8-0.20.0
Time in novel zone, hab. session 10.10.10.3-0.4-0.40.5-0.4-0.30.6-0.20.10.5-0.2-0.3
Total zone transitions, hab. session 10.71.01.81.01.1-1.11.10.7-1.30.30.3-1.30.41.2
Total locomotion distance, hab. session 11.01.52.81.21.3-1.31.31.0-1.70.60.3-1.31.31.4
Locomotion velocity, hab. session 10.71.01.91.11.0-1.01.00.7-1.40.30.1-1.01.11.3
Time in familiar zone, hab. session 20.10.10.80.40.3-0.30.3-0.1-0.5-0.1-0.9-0.40.10.1
Time in novel zone, hab. session 20.40.41.1-0.9-0.70.6-0.6-0.30.8-0.2-0.20.5-1.1-0.8
Total zone transitions, hab. session 21.92.44.31.71.9-1.91.81.4-1.81.10.9-2.10.21.1
Total locomotion distance, hab. session 21.11.43.01.31.4-1.51.41.0-1.60.70.2-1.7-0.00.8
Locomotion velocity, hab. session 21.72.23.91.71.8-1.91.71.3-1.91.00.6-2.00.41.2
Novel to familiar place preference ratio0.40.61.2-0.8-0.91.0-0.9-0.41.00.1-0.21.10.1-0.7
Novelty place preference0.30.41.1-0.5-0.70.8-0.7-0.30.90.2-0.01.10.4-0.6
Time in novel zone, NPP test0.40.51.0-0.6-0.80.8-0.8-0.30.90.2-0.11.00.1-0.9
Total zone transitions, NPP test0.50.81.51.01.1-1.11.00.5-1.10.10.6-1.2-0.40.9
Total locomotion distance, NPP test0.40.61.31.01.0-1.00.90.5-1.10.2-0.1-1.00.00.5
Locomotion velocity, NPP test0.60.81.71.11.1-1.11.00.5-1.30.20.1-1.10.31.0
Intraocular pressure1.22.03.61.51.7-1.61.71.1-1.80.50.7-1.90.61.6
Delta distance traveled before/after self-admin0.40.41.30.60.7-0.60.70.5-0.70.20.0-0.60.61.1
Delta ambulatory time before/after self-admin0.10.10.40.20.3-0.40.40.1-0.5-0.3-0.3-0.40.10.6
Parametrial fat weight1.63.76.0-1.9-2.32.2-2.2-1.72.1-1.2-1.42.4-1.5-1.5
Pavlov. Cond. lever latency0.50.61.7-0.9-0.90.8-0.8-0.50.8-0.3-0.30.6-0.5-1.3
Pavlov. Cond. magazine entry latency0.50.60.90.81.0-0.80.90.7-0.80.80.2-0.90.50.9
Pavlov. Cond. change in total contacts0.10.10.20.30.3-0.30.30.3-0.30.4-0.1-0.30.40.2
Pavlov. Cond. index score0.60.71.20.90.9-0.90.90.7-0.90.80.5-0.70.91.1
Pavlov. Cond. latency score0.50.61.40.90.9-0.80.80.6-0.80.50.2-0.70.61.2
Pavlov. Cond. lever contacts0.10.10.50.50.4-0.30.3-0.0-0.3-0.1-0.1-0.20.20.7
Pavlov. Cond. magazine entry number2.12.63.5-1.8-1.91.8-1.8-1.61.7-1.7-1.01.6-1.4-1.6
Pavlov. Cond. intertrial magazine entries8.29.813.0-3.1-3.23.2-3.3-3.63.2-3.6-2.93.1-2.8-2.3
Pavlov. Cond. lever-magazine prob. diff.0.30.30.60.60.7-0.60.60.5-0.50.60.3-0.50.60.8
Pavlov. Cond. response bias1.01.21.81.31.3-1.31.20.9-1.20.90.4-1.11.01.2
Pavlov. Cond. lever latency2.33.25.0-2.1-2.22.2-2.2-1.62.1-1.2-1.02.2-0.6-1.4
Pavlov. Cond. magazine entry latency0.00.00.20.10.2-0.00.0-0.20.2-0.20.20.10.4-0.2
Pavlov. Cond. change in total contacts1.33.24.42.12.0-2.01.91.8-1.91.71.7-1.61.41.5
Pavlov. Cond. index score0.81.32.31.41.5-1.41.40.9-1.20.60.7-1.30.60.6
Pavlov. Cond. latency score0.50.81.61.11.3-1.11.10.6-1.00.30.4-1.20.30.5
Pavlov. Cond. lever contacts2.43.65.52.32.3-2.32.21.7-2.21.31.1-2.11.01.4
Pavlov. Cond. magazine entry number0.40.50.8-0.8-0.90.8-0.8-0.70.6-0.6-0.90.7-0.5-0.3
Pavlov. Cond. intertrial magazine entries1.53.24.6-1.4-1.81.8-1.9-1.72.1-1.5-1.62.0-1.5-2.1
Pavlov. Cond. lever-magazine prob. diff.0.81.32.41.41.5-1.41.40.9-1.20.60.7-1.30.70.5
Pavlov. Cond. response bias2.12.84.32.02.1-2.12.01.6-1.81.31.3-1.81.01.2
Time in closed arm before self-admin0.81.41.91.21.4-1.11.41.3-1.11.21.2-1.30.80.8
Time in closed arm after self-admin0.10.10.40.2-0.10.3-0.3-0.30.2-0.5-0.10.60.4-0.5
Time in open arm before self-admin0.60.73.5-0.7-0.60.2-0.6-1.00.4-1.2-0.90.2-1.90.1
Time in open arm after self-admin1.11.21.9-1.4-1.31.1-1.3-1.21.3-0.9-1.01.1-0.7-0.6
Bone: periosteal estimation2.76.39.02.92.5-2.42.52.8-2.22.82.8-1.73.01.7
Bone: periosteal perimeter3.57.09.23.02.9-2.62.82.8-2.52.82.6-2.22.72.0
Bone: post-yield work0.50.92.80.80.5-0.60.41.1-0.11.31.50.21.7-0.0
Progressive ratio test 1 active lever presses0.40.82.61.00.7-0.80.70.7-0.60.61.1-0.20.71.6
Progressive ratio test 1 breakpoint0.50.92.91.10.9-0.90.80.8-0.70.71.1-0.40.71.7
Progressive ratio test 1 inactive lever presses0.41.12.21.30.9-0.90.81.2-0.81.21.5-0.31.21.2
Progressive ratio test 2 active lever presses1.82.56.41.91.6-1.51.51.3-1.61.21.4-1.01.42.5
Progressive ratio test 2 breakpoint1.92.56.51.91.6-1.51.51.3-1.61.11.4-0.91.42.5
Progressive ratio test 2 inactive lever presses0.51.75.61.41.2-1.11.21.0-1.20.71.2-0.71.42.4
Incentive Sensitization - Responses0.92.43.61.91.7-1.51.61.3-1.81.00.9-1.21.71.9
Incentive Sensitization - Breakpoint1.02.33.61.81.6-1.41.51.3-1.81.11.0-1.01.81.9
Sum of active levers in priming session hrs 5-60.10.10.6-0.8-0.40.4-0.1-0.10.40.30.10.20.10.2
Progressive ratio0.10.21.40.0-0.20.2-0.2-0.10.2-0.0-0.20.40.3-1.2
Food seeking constrained by brief footshock0.30.31.8-0.1-0.30.4-0.4-0.40.3-0.4-0.20.81.4-0.5
Seeking ratio, punishment vs. effort0.00.10.70.00.1-0.20.10.0-0.2-0.00.3-0.00.30.9
Retroperitoneal fat weight0.20.92.7-0.9-1.31.1-1.2-0.40.90.20.31.6-0.3-0.9
Reaction time number correct0.31.01.7-1.1-1.11.1-1.2-0.91.3-1.0-0.81.1-0.9-0.5
Reaction time mean minus median0.10.30.90.10.6-0.70.70.7-0.40.70.5-0.90.10.3
Reaction time mean minus median AUC0.10.31.00.20.7-0.70.80.6-0.40.70.2-1.0-0.00.2
Reaction time num false alarms0.61.04.20.71.0-0.80.81.0-0.50.91.2-0.92.10.1
Reaction time num false alarms AUC0.41.03.90.60.9-0.80.71.0-0.41.01.3-0.82.00.1
Reaction time trials correct on left0.31.01.7-1.1-1.11.1-1.2-0.91.3-1.0-0.81.1-0.9-0.5
Reaction time trials on left0.31.11.7-1.1-1.11.1-1.2-0.91.3-1.1-0.81.1-0.9-0.5
Reaction time mean0.10.20.60.50.6-0.80.60.4-0.50.4-0.0-0.60.00.3
Reaction time mean AUC0.00.10.20.00.2-0.30.10.1-0.10.1-0.4-0.3-0.40.1
Median of all reaction times0.00.10.20.40.3-0.50.20.2-0.20.1-0.2-0.2-0.0-0.0
Reaction time omissions0.20.40.50.60.7-0.70.70.6-0.50.40.6-0.70.60.6
Reaction time false alarm rate1.11.54.40.91.2-1.01.11.3-0.91.31.4-1.12.10.3
Reaction time premature initiation rate0.60.92.9-0.9-0.60.4-0.4-1.2-0.0-1.7-1.7-0.1-0.8-0.5
Reaction time premature initiations0.51.54.2-1.3-1.00.8-0.8-1.50.5-2.1-1.90.3-1.1-0.6
Std. dev. reaction times0.10.41.10.20.7-0.90.70.4-0.60.30.0-1.1-0.70.5
Reaction time trials completed0.31.11.7-1.1-1.11.1-1.2-0.91.3-1.1-0.81.1-0.9-0.5
Reaction time trials AUC0.20.91.6-1.0-1.11.0-1.1-0.81.3-0.9-0.61.1-0.7-0.5
Run reversals in cocaine runway, females0.70.71.80.70.9-0.91.00.6-1.10.50.3-1.30.21.1
Run reversals in cocaine runway, males0.10.10.5-0.00.2-0.20.30.3-0.20.40.7-0.4-0.60.4
Latency to leave start box in cocaine runway0.71.01.3-0.9-1.01.0-1.0-1.10.9-0.9-0.81.0-1.1-1.1
Latency to leave start box in cocaine runway, F0.10.20.5-0.00.1-0.10.10.3-0.10.70.7-0.2-0.5-0.5
Latency to leave start box in cocaine runway, M2.82.75.5-1.3-1.51.6-1.6-2.11.4-2.3-2.01.6-0.9-0.9
Std. dev. time between licks in bursts0.71.32.81.11.1-1.31.31.0-1.70.60.6-1.30.61.5
Total sessions with >9 infusions2.53.15.91.71.5-1.61.41.9-1.32.12.4-0.81.62.4
Short access day 1 total inactive lever presses0.51.03.10.80.9-0.80.70.9-0.90.70.9-0.61.41.8
Short access day 10 total inactive lever presses0.32.02.71.41.5-1.61.51.6-1.51.51.1-1.61.11.0
Short access day 1 total infusions2.03.97.91.91.8-1.81.71.9-1.71.92.2-1.22.32.8
Short access day 10 total infusions1.21.93.51.51.3-1.31.11.4-1.11.41.9-0.61.51.7
Short access total infusions1.42.05.51.41.2-1.21.01.3-1.01.41.9-0.41.62.4
Short access day 1 locomotion1.01.63.91.01.0-1.01.01.2-0.81.11.6-0.62.01.8
Short access day 10 total locomotion1.04.27.42.22.0-2.01.92.0-1.82.02.7-1.51.72.5
Short access total locomotion2.64.07.91.91.8-1.91.72.0-1.52.12.8-1.22.12.5
One hour access (0.3 mA shock)4.65.57.32.72.5-2.62.42.5-2.22.42.1-2.01.62.5
Compulsive drug intake1.72.55.01.71.5-1.41.41.8-1.61.81.4-1.22.20.9
One hour access (shock baseline)0.82.03.11.51.6-1.71.61.4-1.41.21.3-1.50.11.8
Social response proportion0.30.40.8-0.9-0.80.7-0.6-0.60.4-0.7-0.30.60.4-0.2
Social responses1.92.44.91.31.5-1.41.61.7-1.51.32.2-1.51.71.3
Social time0.10.10.40.10.2-0.20.10.20.20.00.5-0.00.60.5
Soleus weight4.312.716.13.33.7-3.83.83.6-4.03.03.6-3.62.34.0
Bone: stiffness3.15.67.42.62.5-2.42.42.6-2.22.72.6-2.01.81.7
Tibialis anterior weight2.48.211.62.43.0-3.13.22.8-3.42.32.7-3.41.53.1
Time to tail flick, vehicle, before self-admin0.70.91.8-1.3-1.21.0-1.1-0.41.3-0.20.30.9-1.1-0.3
Time to tail flick, vehicle, after self-admin0.71.53.9-1.2-1.41.4-1.6-0.81.3-0.7-0.12.01.1-0.6
Time to tail flick, test, before self-admin0.20.21.6-0.20.0-0.40.00.2-0.1-0.1-0.2-0.4-0.41.3
Time to tail flick, test, after self-admin0.40.41.3-0.1-0.40.6-0.7-0.10.50.10.31.11.1-0.5
Delta time to tail flick, vehicle, before/after SA0.30.32.80.30.1-0.1-0.10.2-0.40.20.30.41.70.4
Delta time to tail flick, test, before/after SA0.40.51.80.1-0.30.7-0.5-0.10.50.20.41.01.1-1.3
Tibia length1.33.78.82.11.7-1.81.62.1-1.72.22.1-1.03.01.1
Ambulatory time before self-admin0.72.03.31.81.6-1.61.61.4-1.51.41.3-1.41.00.7
Ambulatory time after self-admin2.13.44.62.12.1-2.02.11.8-2.11.41.4-1.81.51.6
Bone: tissue strength1.81.93.71.11.0-1.11.01.6-0.91.71.9-0.61.71.8
Total heroin consumption0.30.30.60.30.5-0.50.70.5-0.50.70.6-0.60.80.4
Bone: trabecular number0.61.11.81.01.2-1.11.21.1-1.11.00.4-1.30.51.1
Bone: trabecular spacing1.31.83.0-1.5-1.51.4-1.5-1.71.2-1.7-0.91.4-1.0-0.6
Bone: trabecular thickness0.81.11.81.21.1-1.01.01.1-0.80.80.9-0.71.31.2
Bone: trabecular tissue density0.10.10.70.30.1-0.1-0.00.40.10.70.80.3-0.20.3
Water consumed over 24 hours0.30.51.4-0.2-0.30.6-0.4-1.00.6-1.0-1.00.2-1.2-0.4
Number of responses in last shaping day0.60.81.80.90.6-0.80.60.9-0.71.01.0-0.31.31.3