Hub : Genes

C1h19orf81

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_103994174_103994823 0.03 0.02 2.7e-04 0.02 0.02 0.02 0.02 1.2e-03 1.2e-03 5.7e-04 9.8e-04
2 IC gene expression C1h19orf81 0.05 0.04 9.7e-03 0.02 0.03 0.01 0.02 4.1e-02 1.5e-02 9.4e-02 5.5e-02
3 Brain alternative TSS XM_039104739.2 0.04 0.03 3.9e-04 0.03 0.04 0.03 0.03 6.7e-04 3.0e-04 5.8e-04 5.6e-04
4 NAcc intron excision ratio chr1_103994174_103994564 0.02 0.01 2.8e-04 0.02 0.02 0.02 0.02 2.7e-04 1.8e-04 2.2e-04 3.0e-04
5 Brain alternative TSS NM_001401372.1 0.03 0.02 1.1e-03 0.03 0.03 0.03 0.03 1.7e-03 1.1e-03 1.5e-03 2.0e-03
6 pVTA intron excision ratio chr1_103994174_103994564 0.06 0.04 8.4e-05 0.05 0.05 0.06 0.05 4.0e-05 4.9e-05 1.7e-05 4.4e-05
7 BLA gene expression C1h19orf81 0.09 0.07 3.3e-03 0.06 0.04 0.05 0.06 7.2e-04 2.3e-03 8.5e-04 4.9e-04
8 PL gene expression C1h19orf81 0.03 0.02 2.8e-04 0.03 0.03 0.03 0.03 2.0e-04 3.8e-04 2.1e-04 3.9e-04
9 PL alternative TSS XM_039104739.2 0.03 0.02 5.8e-04 0.02 0.03 0.01 0.01 2.4e-03 5.7e-04 1.8e-02 7.6e-03
10 NAcc gene expression C1h19orf81 0.02 0.02 1.8e-04 0.01 0.02 0.01 0.02 2.2e-03 5.4e-04 3.9e-03 1.3e-03
11 Brain gene expression C1h19orf81 0.06 0.04 4.6e-06 0.03 0.05 0.05 0.04 6.0e-04 2.6e-05 3.0e-05 5.0e-05
12 pVTA intron excision ratio chr1_103994174_103994823 0.04 0.03 1.7e-03 0.03 0.03 0.01 0.03 3.6e-03 2.0e-03 1.9e-02 3.1e-03
13 pVTA gene expression C1h19orf81 0.06 0.04 8.1e-04 0.02 0.03 0.04 0.02 1.2e-02 1.6e-03 7.6e-04 5.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.30.40.9-0.40.6-0.60.60.60.90.10.7-0.70.60.6-0.81.0
Area under the delay curve0.50.61.30.1-0.60.6-0.7-0.60.2-0.9-1.00.8-1.0-1.10.6-0.8
BMI with tail0.31.22.3-0.81.0-1.01.11.11.00.51.1-1.21.21.2-1.21.5
BMI without tail0.10.20.70.60.1-0.20.10.10.4-0.80.2-0.10.0-0.1-0.60.8
Body weight0.83.77.22.7-1.91.9-2.0-1.9-1.8-2.5-1.91.9-1.9-2.01.1-0.9
Weight adjusted by age0.10.10.3-0.40.1-0.10.20.1-0.40.50.3-0.20.40.50.2-0.2
Bone surface0.91.74.2-0.61.3-1.41.11.31.9-0.51.3-1.10.70.5-2.11.8
Bone volume0.40.72.0-0.00.6-0.70.50.71.2-0.70.7-0.60.40.3-1.41.4
Breakpoint value in progressive ratio session0.40.41.3-0.70.5-0.60.50.60.7-0.60.6-0.60.50.4-1.11.0
Number of licking bursts0.20.30.8-0.60.8-0.70.60.60.60.90.5-0.40.20.2-0.3-0.1
Context. condit. distance diff. score8.09.613.1-2.93.5-3.63.33.53.62.23.3-3.12.72.4-3.22.5
Locomotion velocity, session 12.32.46.4-2.11.6-1.51.71.51.02.51.4-1.51.61.7-0.60.3
Locomotion distance, session 13.94.95.6-2.12.2-2.22.32.32.21.92.3-2.32.42.4-2.02.1
Locomotion velocity, session 20.91.03.3-1.21.0-0.91.10.90.71.80.9-1.01.11.2-0.20.3
Locomotion distance, session 20.60.81.0-0.71.0-1.01.00.91.00.80.9-0.90.90.8-0.90.8
Locomotion velocity, session 31.01.24.1-1.31.2-1.11.21.10.72.00.8-1.00.91.0-0.3-0.1
Locomotion distance, session 30.10.10.3-0.20.2-0.10.20.20.20.30.3-0.30.40.5-0.20.5
Stereotopy head waving bouts, day 32.12.43.2-1.11.7-1.71.71.71.61.81.4-1.71.61.6-1.31.2
Stereotopy head waving duration, day 32.32.73.6-1.61.9-1.81.81.81.61.81.5-1.71.61.6-1.41.1
Locomotion velocity, session 70.20.21.3-0.4-0.10.1-0.1-0.1-0.40.6-0.30.4-0.5-0.50.6-1.1
Locomotion distance, session 70.20.20.6-0.40.6-0.60.50.50.80.00.5-0.40.20.1-0.70.5
Stereotopy head waving bouts, day 70.20.21.0-0.60.1-0.00.1-0.0-0.50.8-0.20.1-0.2-0.10.5-1.0
Stereotopy head waving duration, day 70.20.20.9-0.70.1-0.00.10.0-0.50.8-0.20.1-0.0-0.00.5-0.9
Locomotion velocity, session 84.95.913.3-3.02.5-2.32.62.41.73.62.2-2.42.62.7-1.00.9
Locomotion distance, session 89.714.117.0-3.94.1-4.14.14.14.03.43.9-3.93.63.4-3.32.8
Degree of sensitization distance0.20.20.4-0.40.5-0.50.40.50.60.20.4-0.30.20.1-0.40.1
Degree of sensitization stereotypy0.80.82.50.0-0.70.8-0.7-0.8-1.20.0-0.90.9-0.9-0.91.1-1.6
Conditioned locomotion0.10.10.20.3-0.10.1-0.2-0.1-0.3-0.0-0.30.2-0.3-0.30.3-0.5
Cocaine response after cond. corrected1.61.93.11.2-1.71.7-1.5-1.6-1.8-0.7-1.31.3-0.9-0.71.7-1.1
Cocaine response after cond. not corrected1.41.62.51.0-1.51.5-1.3-1.5-1.6-0.6-1.21.2-0.9-0.81.6-1.1
Cocaine response before conditioning0.20.30.5-0.70.7-0.70.60.60.50.50.4-0.40.30.2-0.40.0
Saline control response0.20.20.60.8-0.40.4-0.5-0.4-0.4-0.4-0.50.5-0.6-0.60.3-0.4
Bone: connectivity density1.82.84.5-1.61.8-1.91.71.82.10.81.8-1.71.41.2-1.91.6
Bone: cortical apparent density1.41.93.31.8-1.41.4-1.5-1.4-1.1-1.7-1.31.4-1.5-1.60.8-0.8
Bone: cortical area0.50.72.41.2-0.80.8-0.9-0.8-0.3-1.5-0.70.8-0.9-0.90.10.0
Bone: cortical porosity0.50.63.4-0.90.3-0.20.50.3-0.41.80.2-0.30.60.70.8-0.9
Bone: cortical porosity0.80.84.2-1.30.7-0.60.80.7-0.02.00.5-0.60.81.00.4-0.7
Bone: cortical thickness0.61.01.31.1-1.11.1-1.1-1.1-1.1-0.6-1.01.1-0.9-0.91.1-0.9
Bone: cortical thickness0.10.20.4-0.20.3-0.30.30.30.50.40.6-0.40.50.5-0.30.6
Bone: cortical tissue density1.41.93.21.8-1.41.4-1.5-1.4-1.1-1.7-1.31.4-1.5-1.60.9-0.8
Condit. Reinf. active minus inactive responses0.10.10.40.7-0.10.1-0.2-0.10.3-0.40.10.1-0.2-0.3-0.10.2
Condit. Reinf. active-inactive response ratio0.00.00.00.00.0-0.10.00.10.1-0.10.1-0.0-0.0-0.1-0.1-0.0
Condit. Reinf. active responses0.30.41.11.1-0.50.5-0.6-0.5-0.1-0.9-0.40.6-0.8-0.90.1-0.2
Condit. Reinf. inactive responses0.81.02.01.4-0.90.9-1.1-1.0-0.7-1.4-1.01.0-1.2-1.20.3-0.4
Incentive salience index mean0.00.00.20.5-0.10.1-0.2-0.10.1-0.30.10.2-0.2-0.3-0.00.1
Condit. Reinf. lever presses0.91.31.61.2-1.21.2-1.2-1.2-1.0-1.1-1.01.2-1.2-1.11.0-0.8
Condit. Reinf. active minus inactive responses0.30.41.30.9-0.30.3-0.5-0.4-0.2-0.9-0.50.7-1.0-1.2-0.0-0.6
Condit. Reinf. active-inactive response ratio0.10.20.50.3-0.30.3-0.3-0.3-0.40.1-0.40.4-0.4-0.40.5-0.7
Condit. Reinf. active responses0.50.72.61.2-0.30.3-0.6-0.40.1-1.6-0.50.7-1.1-1.4-0.4-0.1
Condit. Reinf. inactive responses0.50.63.41.0-0.0-0.1-0.20.00.8-1.80.10.1-0.5-0.7-1.21.1
Condit. Reinf. lever presses0.60.83.91.2-0.1-0.0-0.4-0.10.6-2.0-0.20.4-1.0-1.3-1.00.5
Condit. Reinf. lever reinforcers received0.60.83.61.4-0.30.2-0.7-0.40.2-1.9-0.40.7-1.2-1.4-0.60.1
Conditioned reinforcement - actives0.10.10.30.10.2-0.20.30.2-0.20.20.2-0.40.50.5-0.10.3
Conditioned reinforcement - inactives0.00.10.20.30.1-0.2-0.00.1-0.1-0.3-0.30.1-0.3-0.5-0.1-0.2
Conditioned locomotion0.70.91.6-0.40.9-0.91.00.90.80.91.0-1.01.21.2-0.81.3
Patch foraging indifference point 0 sec0.91.65.41.3-0.40.3-0.9-0.6-0.4-2.0-1.11.2-2.0-2.3-0.3-1.2
Patch foraging indifference point AUC0.91.32.5-0.81.2-1.21.21.21.60.61.4-1.11.00.9-1.21.2
Delay disc. indifference point, 0s delay0.60.61.5-0.80.8-0.80.70.81.20.40.8-0.70.60.5-1.00.9
Delay disc. indifference point, 16s delay1.11.22.01.0-1.11.0-1.1-1.1-0.1-0.7-1.31.2-1.4-1.41.2-0.9
Delay disc. indifference point, 2s delay2.22.44.4-1.81.7-1.81.61.72.10.91.4-1.51.31.1-1.71.2
Delay disc. indifference point, 24s delay0.10.10.3-0.40.3-0.30.20.30.40.1-0.1-0.0-0.2-0.3-0.0-0.6
Delay disc. indifference point, 4s delay0.50.51.00.4-0.70.6-0.7-0.7-0.2-1.0-0.90.8-0.9-1.00.5-0.6
Delay disc. indifference point, 8s delay1.92.23.40.5-1.51.4-1.5-1.5-0.8-1.5-1.81.6-1.8-1.81.4-1.6
Indifference point function ln k0.10.10.70.3-0.10.0-0.2-0.10.0-0.8-0.20.2-0.3-0.4-0.40.1
Indifference point function log k0.10.10.70.3-0.10.0-0.2-0.10.0-0.8-0.20.2-0.3-0.4-0.40.1
Patch foraging total patch changes 0 sec0.81.65.31.2-0.50.4-0.9-0.6-0.5-1.9-1.21.2-2.0-2.3-0.1-1.3
Patch foraging total patch changes 12 sec0.20.31.50.80.1-0.2-0.10.10.5-1.20.10.1-0.4-0.6-0.70.5
Patch foraging total patch changes 18 sec1.21.93.7-1.11.9-1.91.51.71.90.51.3-1.20.50.2-1.80.6
Patch foraging total patch changes 24 sec1.93.36.1-1.52.0-2.01.81.92.50.32.0-1.71.31.1-2.42.0
Patch foraging total patch changes 6 sec0.20.31.00.60.1-0.1-0.20.00.2-1.0-0.20.3-0.8-1.0-0.4-0.2
Patch foraging time to switch 0 sec0.61.34.00.1-1.01.2-0.7-1.0-1.91.1-1.10.8-0.20.12.0-1.6
Patch foraging water rate 0 sec0.30.61.8-0.30.9-1.00.50.81.2-0.70.5-0.3-0.3-0.6-1.30.2
Patch foraging water rate 12 sec0.30.71.9-0.61.0-1.00.80.91.3-0.30.8-0.60.2-0.0-1.40.8
Patch foraging water rate 18 sec0.10.10.3-0.60.3-0.30.20.30.5-0.50.2-0.1-0.2-0.3-0.60.1
Patch foraging water rate 24 sec1.21.62.9-0.91.3-1.41.31.41.70.21.5-1.31.00.9-1.61.4
Patch foraging water rate 6 sec0.81.23.9-0.51.0-1.10.81.01.7-1.00.9-0.80.2-0.1-2.01.4
Seeking ratio, delayed vs. immediate footshock0.40.51.0-0.90.5-0.50.60.60.70.30.6-0.70.91.0-0.50.8
Distance traveled before self-admin0.60.82.3-0.81.0-1.10.91.00.9-0.21.0-0.90.60.5-1.50.6
Distance traveled after self-admin0.10.20.5-0.70.2-0.30.40.3-0.40.20.3-0.50.60.6-0.2-0.2
Extensor digitorum longus weight2.38.910.2-3.23.1-3.13.23.22.92.73.2-3.13.03.0-2.62.4
Bone: elastic displacement2.22.54.3-2.11.7-1.61.71.71.32.11.6-1.61.61.6-0.80.6
Bone: elastic work0.30.40.7-0.50.5-0.60.50.60.7-0.10.7-0.60.60.6-0.70.9
Bone: endosteal estimation0.61.34.5-0.10.7-0.80.60.81.5-1.40.9-0.80.60.4-1.92.1
Bone: endosteal perimeter0.30.62.00.20.3-0.40.20.31.0-1.40.4-0.30.1-0.1-1.31.4
Epididymis fat weight0.00.20.80.40.1-0.10.30.2-0.10.90.3-0.30.50.60.30.2
Delta time in closed arm before/after self-admin1.21.12.21.5-0.91.1-0.9-1.0-1.40.2-0.81.0-0.8-0.71.4-1.3
Delta time in open arm before/after self-admin0.20.20.6-0.60.3-0.40.30.30.7-0.30.2-0.30.20.1-0.60.5
Diff in mean of infusions in LGA sessions0.50.71.3-0.71.0-1.00.80.91.00.00.9-0.70.40.2-1.20.8
Delay discount exponential model param0.60.61.3-0.10.7-0.70.80.7-0.00.91.0-0.91.01.1-0.60.9
Extinction: sum of active levers before priming0.30.31.00.30.1-0.10.20.2-0.2-0.40.6-0.60.91.0-0.50.9
Active lever presses in extinction session 60.90.92.3-0.50.6-0.60.70.71.20.31.0-0.91.11.1-0.91.5
Bone: final force0.20.31.50.8-0.60.5-0.6-0.5-0.2-1.2-0.30.4-0.4-0.40.00.3
Bone: final moment0.40.62.21.1-0.80.8-0.9-0.8-0.4-1.5-0.50.7-0.7-0.70.20.2
Food consumed during 24 hour testing period0.91.32.31.2-1.01.0-1.1-1.1-0.9-1.2-1.11.2-1.4-1.50.8-1.0
Glucose0.20.31.0-0.1-0.30.4-0.2-0.4-0.71.0-0.30.3-0.10.11.0-0.9
Heart weight0.50.71.7-0.60.8-0.90.70.91.1-0.40.8-0.80.60.4-1.31.2
Delay discount hyperbolic model param0.30.30.80.10.4-0.40.50.4-0.20.70.8-0.60.80.9-0.40.7
Intermittent access intake day 1-15 change1.12.34.9-1.21.6-1.61.51.61.50.11.5-1.51.31.1-2.21.9
Intermittent access intake escalation0.81.64.2-0.91.3-1.31.11.31.3-0.31.2-1.21.00.8-2.11.9
Intermittent access intake escalation 20.20.20.9-0.50.4-0.50.30.40.1-0.70.4-0.30.20.0-1.00.6
Intermitt. access day 1 inactive lever presses0.20.82.50.01.2-1.20.91.10.4-0.10.9-0.90.50.3-1.60.5
Intermitt. access day 15 inactive lever presses2.14.47.91.9-1.81.7-2.1-1.8-1.8-2.7-2.12.2-2.6-2.81.0-2.0
Intermitt. access escalation Index0.30.51.40.6-0.80.9-0.6-0.8-1.2-0.1-0.70.5-0.2-0.10.9-0.5
Intermittent access day 1 total infusions1.22.02.51.6-1.51.5-1.5-1.5-0.9-1.0-1.61.5-1.5-1.51.5-1.1
Intermittent access day 15 total infusions0.30.51.80.9-0.50.4-0.6-0.50.3-1.3-0.60.6-0.8-0.9-0.20.4
Intermittent access terminal intake (last 3 days)0.10.10.70.4-0.0-0.0-0.2-0.10.2-0.9-0.10.2-0.4-0.5-0.50.4
Intermittent access total infusions0.91.01.71.3-1.11.1-1.1-1.1-0.4-1.2-1.01.1-1.1-1.10.8-0.3
Intermittent access day 1 locomotion0.20.21.11.0-0.40.4-0.4-0.40.4-0.5-0.50.4-0.5-0.50.20.3
Intermittent access day 15 total locomotion1.32.35.3-0.71.5-1.61.41.52.30.41.5-1.41.21.0-1.92.2
Intermittent access total locomotion0.10.20.90.60.1-0.20.10.10.6-0.40.1-0.20.10.1-0.51.0
Intermittent access standard deviation0.00.00.3-0.50.2-0.20.10.2-0.1-0.00.0-0.1-0.0-0.0-0.30.0
Left kidney weight4.621.432.45.7-4.94.9-5.0-4.9-4.4-4.9-4.74.7-4.5-4.53.6-2.9
Right kidney weight5.022.628.55.3-5.15.0-5.1-5.1-4.6-4.8-4.84.9-4.7-4.73.9-3.3
Cocaine induced anxiety0.40.51.50.0-0.70.8-0.6-0.7-1.2-0.2-0.70.7-0.5-0.40.9-1.0
Post-drug Anxiety0.50.62.7-1.60.2-0.20.40.2-0.41.50.1-0.30.60.70.6-0.7
Baseline Anxiety0.91.13.4-1.30.9-0.91.10.90.51.80.9-1.01.21.3-0.20.2
Tail length2.18.113.63.6-2.72.6-3.0-2.7-2.1-3.7-2.72.9-3.3-3.51.5-1.8
Length with tail2.611.417.44.2-3.43.3-3.6-3.4-3.1-3.9-3.33.4-3.5-3.62.3-2.2
Length without tail0.82.73.91.5-1.61.6-1.7-1.7-2.0-1.1-1.71.7-1.6-1.61.6-1.7
Times rat made contact with spout0.10.10.50.10.00.0-0.1-0.1-0.30.1-0.30.3-0.5-0.60.2-0.7
Lifetime Intake2.63.14.22.1-1.91.9-2.0-1.9-1.1-1.9-1.81.9-1.9-1.91.5-0.8
Liver weight, left0.10.21.11.0-0.10.1-0.1-0.10.4-0.70.2-0.10.20.2-0.41.0
Liver weight, right0.10.10.60.8-0.20.2-0.3-0.2-0.1-0.3-0.40.3-0.5-0.60.1-0.3
Locomotor activity1.11.62.21.3-1.31.3-1.4-1.3-1.2-1.3-1.31.4-1.4-1.50.9-1.1
Locomotor testing distance0.20.30.90.5-0.60.5-0.6-0.6-0.4-1.0-0.60.6-0.7-0.70.1-0.2
Locomotor testing rearing0.40.81.60.9-0.90.9-1.0-0.9-0.6-1.3-0.90.9-1.0-1.00.3-0.2
Locomotion in novel chamber1.72.16.61.2-1.61.6-1.5-1.5-2.6-1.3-1.11.3-1.1-1.01.3-1.3
Locomotion in novel chamber post-restriction0.61.02.3-0.70.8-0.80.90.91.00.11.1-1.01.11.1-1.21.5
Fecal boli incidents, locomotor time 10.91.31.90.8-1.11.1-1.2-1.1-0.6-0.8-1.31.3-1.4-1.41.4-1.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.50.2-0.20.20.2-0.30.5-0.1-0.20.20.2-0.0-0.3
Time >=10cm from walls, locomotor time 15.76.07.42.7-2.62.6-2.6-2.6-2.6-2.6-2.52.5-2.3-2.32.0-1.7
Bouts of movement, locomotor time 13.13.54.51.8-2.12.1-2.0-2.1-2.1-1.4-2.01.9-1.7-1.52.0-1.5
Total resting periods, locomotor time 12.73.04.31.7-1.91.9-1.8-1.9-2.1-1.1-1.81.7-1.5-1.32.0-1.5
Rest time, locomotor task time 10.10.10.40.3-0.10.1-0.1-0.1-0.40.6-0.10.1-0.1-0.00.6-0.5
Distance moved, locomotor task time 13.24.85.9-1.92.2-2.22.32.31.81.42.3-2.42.42.4-2.32.3
Vertical activity count, locomotor time 10.10.11.00.1-0.10.0-0.2-0.1-0.2-1.0-0.20.1-0.3-0.4-0.6-0.0
Time >=10cm from walls, locomotor time 20.91.32.90.9-1.11.1-1.1-1.1-1.7-0.5-1.31.1-0.9-0.91.3-1.6
Bouts of movement, locomotor time 20.20.31.11.0-0.40.3-0.5-0.4-0.3-1.0-0.20.3-0.5-0.5-0.3-0.0
Total resting periods, locomotor time 20.20.31.21.1-0.50.4-0.6-0.5-0.4-1.1-0.30.4-0.5-0.5-0.20.1
Rest time, locomotor task time 20.40.61.11.0-0.90.9-0.8-0.9-0.7-0.4-0.80.7-0.5-0.50.9-0.3
Distance moved, locomotor task time 21.61.92.5-1.21.5-1.51.51.51.11.01.6-1.51.41.3-1.51.2
Vertical activity count, locomotor time 20.20.31.2-0.1-0.30.3-0.4-0.4-0.8-0.4-0.60.5-0.6-0.70.4-1.1
Light reinforcement 10.20.41.3-0.50.8-0.90.70.80.8-0.20.5-0.60.20.0-1.10.5
Light reinforcement 20.30.51.5-1.10.7-0.70.70.70.21.20.3-0.60.60.6-0.1-0.3
Bone: marrow area0.61.34.6-0.20.8-0.90.70.91.6-1.31.0-0.90.60.4-1.92.1
Bone: maximum diameter0.61.03.91.2-0.90.9-1.0-0.9-0.4-2.0-0.80.9-1.1-1.20.10.0
Bone: maximum force0.30.52.50.30.1-0.20.10.20.8-1.20.5-0.40.40.3-1.01.6
Bone: maximum moment0.30.42.10.7-0.10.0-0.1-0.00.6-1.50.3-0.10.10.0-0.91.4
Mean time between licks in bursts0.00.10.6-0.2-0.10.10.0-0.1-0.40.8-0.20.10.00.10.5-0.6
Mean num. licks in bursts0.00.10.40.3-0.20.2-0.2-0.2-0.2-0.6-0.20.1-0.1-0.1-0.10.2
Cd content in liver1.82.02.71.7-1.31.3-1.5-1.4-1.3-1.5-1.41.5-1.6-1.61.0-1.0
Co content in liver0.40.40.90.4-0.70.8-0.6-0.7-1.0-0.1-0.70.6-0.5-0.40.8-0.7
Cu content in liver1.31.62.1-1.01.3-1.31.31.31.50.81.4-1.31.31.2-1.31.4
Fe content in liver2.12.53.6-1.81.9-1.91.71.81.91.01.5-1.51.21.0-1.81.1
K content in liver0.20.20.9-0.4-0.10.1-0.1-0.1-0.30.2-0.20.3-0.4-0.50.4-0.9
Mg content in liver0.50.51.60.1-0.50.5-0.5-0.6-0.80.1-0.60.7-0.7-0.70.9-1.3
Mn content in liver0.10.10.5-0.7-0.10.10.1-0.0-0.50.6-0.0-0.00.20.30.5-0.5
Na content in liver0.10.10.5-0.70.3-0.20.30.30.30.40.3-0.30.30.4-0.20.1
Rb content in liver1.92.23.6-1.61.9-1.91.71.81.61.21.3-1.51.10.9-1.60.8
Se content in liver0.20.20.4-0.40.4-0.50.40.40.6-0.30.6-0.40.20.1-0.60.4
Sr content in liver0.10.10.30.20.3-0.30.20.30.4-0.30.0-0.20.0-0.0-0.60.4
Zn content in liver0.30.30.60.7-0.40.4-0.5-0.4-0.4-0.7-0.40.6-0.7-0.80.3-0.5
Bone: minimum diameter1.01.84.8-0.41.1-1.21.01.21.8-0.71.3-1.20.90.8-2.12.2
Time in familiar zone, hab. session 10.10.10.50.3-0.20.2-0.3-0.2-0.1-0.7-0.30.3-0.4-0.5-0.1-0.1
Time in novel zone, hab. session 10.20.20.6-0.50.4-0.40.40.40.20.80.5-0.40.50.50.0-0.0
Total zone transitions, hab. session 10.91.31.9-1.41.1-1.11.21.10.91.41.1-1.21.31.3-0.70.7
Total locomotion distance, hab. session 10.60.81.0-0.91.0-1.01.01.00.90.71.0-0.90.90.8-0.80.7
Locomotion velocity, hab. session 10.20.20.3-0.50.5-0.50.50.50.30.60.5-0.50.50.5-0.30.2
Time in familiar zone, hab. session 20.80.84.61.3-0.30.1-0.5-0.20.4-2.1-0.30.4-0.8-1.1-0.90.7
Time in novel zone, hab. session 21.41.53.3-1.71.1-1.01.31.10.81.81.2-1.21.41.5-0.40.4
Total zone transitions, hab. session 21.41.82.4-1.11.5-1.51.51.51.51.21.4-1.41.21.1-1.41.2
Total locomotion distance, hab. session 21.21.62.6-0.71.4-1.41.31.41.60.61.4-1.31.00.9-1.51.4
Locomotion velocity, hab. session 20.50.61.0-0.41.0-1.00.80.91.00.50.9-0.80.60.5-0.90.7
Novel to familiar place preference ratio0.40.41.7-0.1-0.40.4-0.4-0.4-0.60.2-0.40.6-0.7-0.70.8-1.3
Novelty place preference0.20.21.3-0.2-0.10.2-0.2-0.2-0.40.4-0.30.4-0.5-0.50.6-1.1
Time in novel zone, NPP test0.10.10.9-0.2-0.00.0-0.1-0.1-0.30.3-0.20.3-0.5-0.50.4-0.9
Total zone transitions, NPP test2.02.94.5-1.61.5-1.51.71.61.51.81.8-1.82.02.1-1.21.7
Total locomotion distance, NPP test4.25.77.3-1.82.4-2.42.42.42.71.62.7-2.52.52.5-2.32.7
Locomotion velocity, NPP test3.14.45.5-1.72.0-2.02.12.12.21.82.3-2.22.32.3-1.82.2
Intraocular pressure4.97.19.42.3-3.13.1-2.9-3.0-3.1-2.3-2.72.7-2.3-2.12.7-2.1
Delta distance traveled before/after self-admin0.40.41.20.4-0.70.7-0.6-0.6-1.1-0.2-0.70.5-0.3-0.31.0-0.6
Delta ambulatory time before/after self-admin0.10.10.6-0.1-0.10.1-0.0-0.1-0.80.3-0.20.1-0.00.00.6-0.7
Parametrial fat weight1.53.46.31.1-1.92.0-1.7-1.9-2.5-0.1-2.11.8-1.4-1.22.5-2.4
Pavlov. Cond. lever latency0.50.71.1-0.91.0-1.00.91.00.90.40.7-0.80.60.5-1.10.7
Pavlov. Cond. magazine entry latency0.40.61.91.4-0.70.7-0.8-0.7-0.4-0.8-0.60.7-0.8-0.90.4-0.3
Pavlov. Cond. change in total contacts0.40.40.70.8-0.70.7-0.7-0.7-0.7-0.3-0.60.7-0.6-0.60.7-0.6
Pavlov. Cond. index score1.41.82.61.6-1.41.4-1.4-1.4-1.3-0.8-1.31.4-1.3-1.21.4-1.2
Pavlov. Cond. latency score1.51.93.11.7-1.51.5-1.5-1.5-1.3-1.0-1.31.4-1.3-1.21.4-1.1
Pavlov. Cond. lever contacts1.01.21.61.2-1.21.2-1.2-1.2-1.1-0.7-1.01.1-0.9-0.81.2-0.9
Pavlov. Cond. magazine entry number0.40.61.2-1.10.7-0.80.80.80.70.40.7-0.80.70.7-0.70.7
Pavlov. Cond. intertrial magazine entries0.80.91.9-1.41.0-1.01.01.00.71.21.0-0.90.90.9-0.60.3
Pavlov. Cond. lever-magazine prob. diff.0.60.71.01.0-0.80.9-0.8-0.9-0.9-0.2-0.80.9-0.8-0.71.0-0.9
Pavlov. Cond. response bias0.91.11.41.2-1.11.1-1.1-1.1-1.1-0.5-1.01.1-1.0-1.01.2-1.1
Pavlov. Cond. lever latency0.60.82.20.3-0.91.0-0.7-0.9-1.40.6-0.90.6-0.2-0.01.5-1.1
Pavlov. Cond. magazine entry latency0.50.61.5-0.20.9-1.00.70.91.2-0.30.7-0.60.2-0.0-1.20.7
Pavlov. Cond. change in total contacts0.50.95.01.3-0.30.1-0.6-0.30.5-2.2-0.20.5-1.0-1.3-0.90.6
Pavlov. Cond. index score0.60.82.70.00.9-1.00.60.91.4-1.00.8-0.50.0-0.3-1.61.1
Pavlov. Cond. latency score0.60.82.3-0.20.9-1.00.70.91.3-0.70.8-0.60.1-0.1-1.51.0
Pavlov. Cond. lever contacts0.60.82.4-0.10.8-0.90.60.81.4-0.80.9-0.60.2-0.0-1.61.3
Pavlov. Cond. magazine entry number1.01.23.50.2-1.21.3-0.9-1.1-1.60.8-1.10.8-0.3-0.01.9-1.3
Pavlov. Cond. intertrial magazine entries0.20.30.50.6-0.60.6-0.6-0.6-0.7-0.1-0.60.6-0.5-0.50.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.50.72.30.20.8-0.90.50.71.3-1.10.7-0.4-0.1-0.4-1.51.0
Pavlov. Cond. response bias0.91.23.70.01.0-1.10.71.01.7-1.11.1-0.70.2-0.1-1.91.6
Time in closed arm before self-admin0.10.20.7-0.90.2-0.20.40.30.10.60.4-0.40.50.60.10.0
Time in closed arm after self-admin1.81.93.2-1.01.3-1.21.41.30.91.71.7-1.51.71.8-0.81.1
Time in open arm before self-admin0.40.42.61.6-0.40.4-0.5-0.4-0.1-1.1-0.10.3-0.3-0.3-0.20.6
Time in open arm after self-admin0.10.10.60.2-0.00.0-0.1-0.00.4-0.8-0.20.0-0.2-0.2-0.50.4
Bone: periosteal estimation0.30.73.00.60.2-0.30.00.21.0-1.70.4-0.30.0-0.1-1.41.6
Bone: periosteal perimeter0.10.20.90.3-0.0-0.0-0.00.00.5-0.90.1-0.10.0-0.1-0.60.8
Bone: post-yield work0.30.42.0-0.00.2-0.30.30.30.8-0.80.6-0.50.50.4-0.91.4
Progressive ratio test 1 active lever presses2.63.25.72.4-1.81.8-1.9-1.8-1.2-1.9-1.91.8-1.9-1.91.3-1.0
Progressive ratio test 1 breakpoint2.32.85.52.4-1.71.6-1.8-1.7-1.1-1.9-1.81.7-1.8-1.91.2-0.9
Progressive ratio test 1 inactive lever presses1.82.66.72.4-1.51.4-1.7-1.4-0.9-2.6-1.51.5-1.8-1.90.4-0.3
Progressive ratio test 2 active lever presses1.21.42.11.0-1.21.2-1.3-1.2-0.9-1.4-1.31.3-1.4-1.40.9-0.8
Progressive ratio test 2 breakpoint1.71.92.71.2-1.41.4-1.5-1.4-1.1-1.6-1.51.5-1.6-1.61.0-0.9
Progressive ratio test 2 inactive lever presses0.30.41.10.5-0.60.5-0.7-0.6-0.4-1.1-0.70.7-0.8-0.90.3-0.3
Incentive Sensitization - Responses0.10.10.5-0.2-0.10.0-0.1-0.00.1-0.7-0.10.1-0.3-0.4-0.20.3
Incentive Sensitization - Breakpoint0.10.10.5-0.2-0.10.1-0.2-0.10.0-0.7-0.20.2-0.4-0.5-0.20.2
Sum of active levers in priming session hrs 5-62.72.54.5-1.71.7-1.81.51.71.80.21.6-1.51.21.0-2.11.6
Progressive ratio0.30.51.30.2-0.40.4-0.6-0.5-0.2-0.7-0.80.8-1.1-1.20.3-0.7
Food seeking constrained by brief footshock0.70.81.80.9-1.01.0-1.0-1.0-0.3-1.3-0.80.9-0.9-0.90.6-0.2
Seeking ratio, punishment vs. effort0.10.10.60.5-0.30.3-0.1-0.2-0.1-0.20.2-0.20.50.60.10.8
Retroperitoneal fat weight0.73.14.32.1-1.91.9-1.8-1.9-2.1-0.7-1.81.8-1.5-1.32.1-1.7
Reaction time number correct3.16.07.0-2.32.4-2.42.52.42.61.52.6-2.62.62.6-2.32.6
Reaction time mean minus median0.30.72.00.30.7-0.80.50.71.3-0.50.8-0.60.30.1-1.41.4
Reaction time mean minus median AUC0.20.51.40.20.6-0.60.50.61.00.00.8-0.60.50.5-0.91.2
Reaction time num false alarms1.21.73.7-0.31.5-1.61.31.51.8-0.01.3-1.20.70.4-1.91.4
Reaction time num false alarms AUC0.20.31.00.20.8-0.90.50.70.9-0.30.5-0.4-0.1-0.3-1.00.3
Reaction time trials correct on left3.16.07.0-2.32.4-2.42.52.42.61.52.6-2.62.62.6-2.32.6
Reaction time trials on left2.85.26.4-2.12.2-2.22.32.32.51.42.5-2.42.42.4-2.22.5
Reaction time mean1.01.53.31.7-1.21.1-1.3-1.2-0.8-1.8-1.11.2-1.4-1.50.5-0.5
Reaction time mean AUC0.91.42.51.4-1.21.1-1.3-1.2-0.9-1.6-1.11.2-1.3-1.40.7-0.7
Median of all reaction times2.02.93.91.9-1.71.7-1.8-1.7-1.5-2.0-1.61.8-1.9-1.91.2-1.2
Reaction time omissions2.23.34.01.8-2.02.0-2.0-2.0-1.9-1.5-1.71.9-1.8-1.71.7-1.5
Reaction time false alarm rate0.30.41.51.0-0.20.1-0.4-0.2-0.2-0.7-0.60.6-1.0-1.20.0-0.8
Reaction time premature initiation rate2.02.84.71.0-1.71.7-1.6-1.7-2.1-0.5-1.91.7-1.6-1.52.0-2.2
Reaction time premature initiations0.20.30.8-0.1-0.60.6-0.5-0.6-0.80.2-0.60.5-0.3-0.20.9-0.8
Std. dev. reaction times0.20.31.61.0-0.20.2-0.4-0.20.2-1.2-0.10.3-0.6-0.7-0.50.5
Reaction time trials completed2.85.26.4-2.12.2-2.22.32.32.51.42.5-2.42.42.4-2.22.5
Reaction time trials AUC2.64.96.0-2.02.2-2.22.22.22.41.32.4-2.32.42.3-2.12.4
Run reversals in cocaine runway, females2.22.24.3-0.41.5-1.61.51.52.10.91.4-1.51.31.2-1.62.0
Run reversals in cocaine runway, males0.30.30.6-0.60.5-0.50.50.50.60.30.6-0.60.60.6-0.60.8
Latency to leave start box in cocaine runway8.39.412.6-2.53.2-3.33.13.23.62.03.2-3.22.92.8-3.43.1
Latency to leave start box in cocaine runway, F5.05.88.3-2.22.4-2.52.42.52.91.52.5-2.52.32.2-2.52.5
Latency to leave start box in cocaine runway, M3.73.45.1-1.42.1-2.12.02.11.81.41.9-2.01.71.6-2.31.4
Std. dev. time between licks in bursts0.10.10.40.3-0.10.1-0.2-0.2-0.3-0.5-0.40.3-0.5-0.60.0-0.5
Total sessions with >9 infusions5.56.68.02.5-2.82.7-2.8-2.8-1.8-2.3-2.82.8-2.8-2.82.5-1.9
Short access day 1 total inactive lever presses0.60.71.30.3-0.80.7-0.9-0.8-0.6-0.8-1.01.0-1.1-1.20.7-0.9
Short access day 10 total inactive lever presses1.12.74.4-1.41.9-2.01.81.91.50.71.7-1.71.41.1-2.11.2
Short access day 1 total infusions2.83.84.41.8-2.12.0-2.0-2.0-2.0-1.7-2.12.0-1.9-1.91.9-1.7
Short access day 10 total infusions4.76.07.32.7-2.62.6-2.7-2.6-1.4-2.3-2.62.6-2.6-2.62.2-1.6
Short access total infusions6.98.810.83.2-3.33.3-3.3-3.3-2.2-2.8-3.13.2-3.0-2.92.7-1.9
Short access day 1 locomotion2.02.45.32.3-1.51.4-1.6-1.5-1.2-2.1-1.51.5-1.7-1.80.8-0.6
Short access day 10 total locomotion0.10.21.10.1-0.00.10.0-0.1-0.41.1-0.40.2-0.10.00.8-0.9
Short access total locomotion1.82.22.81.6-1.51.5-1.5-1.5-1.0-0.9-1.71.6-1.7-1.61.6-1.3
One hour access (0.3 mA shock)0.10.10.4-0.00.1-0.1-0.10.10.6-0.6-0.10.1-0.4-0.5-0.40.5
Compulsive drug intake0.10.20.9-1.0-0.20.2-0.1-0.2-0.60.0-0.40.2-0.1-0.10.3-0.5
One hour access (shock baseline)0.10.10.40.6-0.20.2-0.3-0.20.2-0.7-0.20.3-0.4-0.5-0.10.3
Social response proportion3.13.54.42.1-1.81.9-1.9-1.9-2.1-0.9-1.92.0-1.9-1.81.9-1.8
Social responses1.62.12.81.7-1.41.4-1.5-1.5-1.5-0.8-1.41.5-1.6-1.51.4-1.4
Social time0.40.61.2-0.20.8-0.80.70.80.90.10.7-0.70.50.4-1.11.1
Soleus weight1.64.97.6-2.82.4-2.42.42.42.12.32.2-2.22.12.0-1.71.3
Bone: stiffness0.30.51.90.00.4-0.50.40.50.8-0.40.6-0.60.60.5-1.01.4
Tibialis anterior weight0.31.11.3-1.11.1-1.01.11.11.01.11.1-1.11.11.1-0.80.9
Time to tail flick, vehicle, before self-admin1.21.31.9-1.01.1-1.01.21.11.31.31.1-1.21.31.4-0.70.9
Time to tail flick, vehicle, after self-admin1.92.53.7-0.81.7-1.71.71.71.41.31.9-1.71.61.5-1.61.6
Time to tail flick, test, before self-admin0.40.41.0-1.00.7-0.70.70.70.20.70.6-0.60.60.6-0.60.2
Time to tail flick, test, after self-admin1.71.83.7-0.91.4-1.41.31.41.91.11.2-1.31.11.1-1.31.6
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.20.2-0.20.20.2-0.10.30.2-0.10.10.1-0.00.1
Delta time to tail flick, test, before/after SA0.10.10.30.50.1-0.10.10.10.60.30.0-0.10.10.1-0.00.4
Tibia length4.612.822.84.5-3.83.7-3.9-3.7-2.7-4.8-3.33.6-3.7-3.82.0-1.5
Ambulatory time before self-admin0.20.41.5-0.30.6-0.60.50.60.6-0.60.7-0.50.30.2-1.20.5
Ambulatory time after self-admin0.10.10.2-0.40.3-0.30.30.3-0.2-0.10.4-0.30.30.3-0.3-0.2
Bone: tissue strength0.30.30.40.3-0.60.6-0.6-0.6-0.7-0.5-0.60.6-0.5-0.50.6-0.5
Total heroin consumption0.80.93.9-2.01.0-1.00.91.00.60.40.9-0.80.70.6-0.90.4
Bone: trabecular number0.50.91.6-0.80.8-0.90.90.91.20.31.0-1.01.01.0-1.11.3
Bone: trabecular spacing0.70.91.20.9-1.11.1-1.0-1.1-1.0-0.7-0.91.0-0.9-0.81.0-0.8
Bone: trabecular thickness0.10.10.50.7-0.10.0-0.1-0.00.4-0.70.1-0.0-0.0-0.1-0.40.7
Bone: trabecular tissue density0.91.34.11.7-1.00.9-1.1-1.0-0.5-2.0-0.91.0-1.2-1.30.1-0.1
Water consumed over 24 hours0.30.40.9-0.71.0-0.90.80.80.60.90.5-0.50.20.1-0.5-0.3
Number of responses in last shaping day2.02.23.31.8-1.51.5-1.5-1.5-1.4-1.1-1.71.5-1.4-1.41.4-1.3