Hub : Genes

C19h19orf53

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression C19h19orf53 0.04 0.02 7.9e-05 0.03 0.02 0.02 0.02 7.9e-06 4.3e-04 5.7e-04 1.1e-04
2 Brain gene expression C19h19orf53 0.07 0.04 5.6e-05 0.05 0.04 0.04 0.05 1.2e-05 2.2e-04 1.5e-04 2.9e-05
3 PL gene expression C19h19orf53 0.07 0.03 8.5e-07 0.05 0.06 0.05 0.06 3.5e-06 4.9e-07 1.6e-06 9.6e-07
4 IC gene expression C19h19orf53 0.1 0.06 6.8e-03 0.01 0.02 0 0.01 1.2e-01 5.6e-02 2.0e-01 8.4e-02
5 pVTA gene expression C19h19orf53 0.07 0.04 1.1e-05 0.04 0.06 0.06 0.06 6.4e-04 2.5e-05 1.6e-05 1.9e-05
6 NAcc intron excision ratio chr19_40819923_40822100 0.03 0.02 5.3e-04 0.02 0.02 0.02 0.02 4.5e-04 4.4e-04 1.7e-03 5.6e-04
7 RMTg gene expression C19h19orf53 0.15 0.1 6.7e-03 0.11 0.1 0.03 0.08 8.5e-04 1.1e-03 5.4e-02 3.6e-03
8 NAcc intron excision ratio chr19_40820065_40822100 0.05 0.02 1.4e-07 0.06 0.05 0.05 0.06 7.4e-09 1.2e-07 9.3e-08 8.9e-09
9 Liver gene expression C19h19orf53 0.06 0.04 5.0e-03 -0 0 0 -0 8.1e-01 1.1e-01 1.0e-01 4.9e-01
10 Adipose gene expression C19h19orf53 0.05 0.03 3.3e-05 0.03 0.03 0.02 0.03 5.4e-04 1.4e-04 1.3e-03 2.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.13.79.53.13.12.31.72.2-0.21.90.90.0-0.8
Area under the delay curve0.40.51.6-0.5-0.5-0.3-0.6-0.11.1-0.2-0.9-1.3-0.4
BMI with tail1.96.612.1-3.1-3.1-3.0-2.4-3.00.4-3.5-0.62.02.4
BMI without tail0.10.40.9-0.5-0.5-0.8-0.9-0.20.7-0.9-0.7-0.20.3
Body weight0.10.41.9-0.6-0.6-0.00.50.1-1.4-0.10.30.70.5
Weight adjusted by age0.30.40.8-0.9-0.9-0.5-0.6-0.80.8-0.4-0.2-0.8-0.1
Bone surface1.93.57.02.62.61.91.22.50.21.9-0.5-1.0-2.2
Bone volume2.24.08.62.92.92.11.52.6-0.02.0-0.1-0.7-2.0
Breakpoint value in progressive ratio session1.61.95.00.00.00.61.3-0.3-2.20.12.21.91.9
Number of licking bursts0.20.30.50.50.50.70.70.6-0.60.60.5-0.10.6
Context. condit. distance diff. score0.70.82.6-1.6-1.6-1.0-0.7-0.80.0-0.4-0.3-0.80.5
Locomotion velocity, session 10.90.92.01.41.41.11.01.2-0.70.70.30.6-0.3
Locomotion distance, session 10.60.71.80.70.70.91.10.7-1.30.20.90.80.8
Locomotion velocity, session 20.50.50.90.90.90.90.80.9-0.31.00.2-0.50.0
Locomotion distance, session 20.50.72.4-0.0-0.00.40.90.2-1.6-0.01.10.81.3
Locomotion velocity, session 30.20.20.5-0.2-0.2-0.4-0.6-0.10.6-0.4-0.6-0.7-0.5
Locomotion distance, session 31.31.55.80.40.40.3-0.21.21.20.9-1.3-2.4-1.7
Stereotopy head waving bouts, day 31.71.94.3-0.9-0.9-1.4-1.8-0.62.0-1.1-2.1-1.0-1.3
Stereotopy head waving duration, day 30.80.91.7-0.8-0.8-1.1-1.3-0.81.3-1.1-1.2-0.3-0.3
Locomotion velocity, session 70.20.30.9-0.7-0.7-0.5-0.4-0.10.3-0.1-0.5-1.0-0.2
Locomotion distance, session 70.30.40.80.40.40.70.90.5-0.90.50.8-0.10.4
Stereotopy head waving bouts, day 71.61.96.80.10.1-0.3-0.90.71.90.3-1.9-2.6-1.8
Stereotopy head waving duration, day 71.11.34.00.70.70.2-0.41.11.50.7-1.4-2.0-1.5
Locomotion velocity, session 80.30.42.1-0.0-0.00.50.90.5-1.50.60.50.20.3
Locomotion distance, session 80.30.51.4-0.7-0.7-0.00.4-0.1-1.20.10.8-0.01.2
Degree of sensitization distance1.41.54.1-0.1-0.10.31.0-0.6-1.9-0.21.72.01.7
Degree of sensitization stereotypy1.01.14.50.00.0-0.2-0.70.61.40.2-1.5-2.1-1.2
Conditioned locomotion0.20.20.50.20.20.50.60.4-0.70.40.40.3-0.0
Cocaine response after cond. corrected0.70.82.0-0.7-0.7-0.20.4-0.6-1.4-0.31.21.41.3
Cocaine response after cond. not corrected1.01.22.8-0.5-0.50.00.6-0.6-1.6-0.11.61.61.7
Cocaine response before conditioning0.20.30.50.70.70.50.30.60.20.60.1-0.5-0.2
Saline control response2.73.66.41.61.62.32.51.4-2.51.62.51.01.2
Bone: connectivity density3.14.811.53.43.42.51.62.80.42.30.3-0.8-1.6
Bone: cortical apparent density0.71.02.9-0.7-0.7-1.0-1.4-0.61.7-0.7-1.1-0.80.0
Bone: cortical area0.30.51.40.20.20.81.00.8-1.20.60.6-0.4-0.1
Bone: cortical porosity0.30.31.0-1.0-1.0-0.4-0.1-0.8-0.5-0.40.1-0.10.2
Bone: cortical porosity0.20.30.8-0.9-0.9-0.20.0-0.3-0.4-0.1-0.2-0.7-0.4
Bone: cortical thickness0.50.82.4-1.6-1.6-0.8-0.4-0.8-0.5-0.90.2-0.30.9
Bone: cortical thickness2.42.812.0-0.4-0.40.20.7-1.2-1.4-0.82.81.83.5
Bone: cortical tissue density0.71.03.1-0.7-0.7-1.0-1.3-0.51.8-0.6-1.2-0.9-0.1
Condit. Reinf. active minus inactive responses2.63.012.3-1.6-1.6-1.0-1.30.11.60.0-1.9-3.5-1.7
Condit. Reinf. active-inactive response ratio1.21.24.8-1.7-1.7-0.8-0.7-0.40.5-0.1-0.6-2.2-0.3
Condit. Reinf. active responses1.62.08.3-0.9-0.9-0.5-1.00.41.60.3-1.8-2.9-1.7
Condit. Reinf. inactive responses1.21.52.71.61.61.30.81.60.31.3-0.5-0.5-1.4
Incentive salience index mean2.02.510.9-0.3-0.3-0.1-0.71.11.60.6-1.9-3.3-2.4
Condit. Reinf. lever presses1.62.26.71.01.00.6-0.01.71.31.2-1.5-2.2-2.6
Condit. Reinf. active minus inactive responses0.20.30.80.40.40.20.20.7-0.20.2-0.6-0.6-0.9
Condit. Reinf. active-inactive response ratio0.00.00.1-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.20.1-0.1
Condit. Reinf. active responses0.10.10.50.40.40.30.40.5-0.7-0.10.20.1-0.1
Condit. Reinf. inactive responses0.30.41.1-0.0-0.00.00.3-0.3-0.9-0.71.00.91.1
Condit. Reinf. lever presses0.10.10.3-0.1-0.1-0.4-0.4-0.30.3-0.6-0.4-0.00.0
Condit. Reinf. lever reinforcers received0.00.10.10.30.30.20.20.3-0.4-0.2-0.00.0-0.1
Conditioned reinforcement - actives0.00.00.10.20.20.10.20.2-0.30.20.20.3-0.0
Conditioned reinforcement - inactives0.10.10.50.10.1-0.2-0.20.20.30.0-0.4-0.7-0.5
Conditioned locomotion0.10.10.4-0.0-0.0-0.5-0.50.00.4-0.4-0.70.5-0.2
Patch foraging indifference point 0 sec0.20.41.5-0.5-0.5-0.1-0.20.30.1-0.1-0.9-1.0-1.2
Patch foraging indifference point AUC1.21.83.01.71.71.51.51.2-1.21.21.11.10.2
Delay disc. indifference point, 0s delay0.40.40.80.90.90.70.50.90.10.6-0.30.2-0.8
Delay disc. indifference point, 16s delay0.70.71.5-1.2-1.2-0.8-0.6-1.10.1-0.80.20.31.1
Delay disc. indifference point, 2s delay0.80.92.2-0.8-0.8-0.9-1.2-0.71.5-0.6-0.9-1.1-0.3
Delay disc. indifference point, 24s delay0.50.61.7-1.1-1.1-0.5-0.4-0.20.3-0.0-0.8-1.3-0.5
Delay disc. indifference point, 4s delay0.60.72.30.80.80.3-0.40.61.50.2-0.9-1.0-0.9
Delay disc. indifference point, 8s delay0.70.92.6-1.0-1.0-0.6-0.8-0.21.2-0.5-1.2-1.6-0.5
Indifference point function ln k1.83.24.7-2.1-2.1-2.0-2.2-1.12.0-1.6-2.1-1.5-1.0
Indifference point function log k1.83.24.7-2.1-2.1-2.0-2.2-1.12.0-1.6-2.1-1.5-1.0
Patch foraging total patch changes 0 sec0.20.40.9-0.8-0.8-0.4-0.4-0.10.1-0.5-0.9-0.7-0.9
Patch foraging total patch changes 12 sec1.31.73.31.31.31.61.61.8-1.21.50.5-0.8-0.6
Patch foraging total patch changes 18 sec2.03.15.12.32.32.22.12.2-1.51.60.90.2-0.5
Patch foraging total patch changes 24 sec1.01.83.51.61.61.51.31.9-0.61.60.1-0.7-1.3
Patch foraging total patch changes 6 sec0.30.50.90.80.81.00.90.7-0.60.50.60.2-0.0
Patch foraging time to switch 0 sec0.10.30.50.40.40.60.70.4-0.50.60.7-0.30.3
Patch foraging water rate 0 sec0.10.20.9-0.3-0.3-0.3-0.1-0.4-0.5-0.70.00.90.2
Patch foraging water rate 12 sec0.81.64.6-0.5-0.5-1.3-1.7-0.52.1-1.2-1.9-0.9-0.7
Patch foraging water rate 18 sec1.52.35.80.40.4-0.6-1.30.82.3-0.2-2.4-1.9-2.2
Patch foraging water rate 24 sec1.11.63.7-0.7-0.7-1.0-1.4-0.01.8-0.5-1.9-1.6-1.4
Patch foraging water rate 6 sec2.02.96.02.42.42.01.82.0-1.11.61.10.8-0.2
Seeking ratio, delayed vs. immediate footshock1.72.03.4-1.7-1.7-1.6-1.6-1.81.3-1.8-0.50.11.0
Distance traveled before self-admin0.60.81.4-1.0-1.0-1.1-1.2-1.11.0-1.0-0.6-0.1-0.1
Distance traveled after self-admin0.50.61.3-0.5-0.5-1.1-1.2-0.81.0-0.9-0.6-0.20.1
Extensor digitorum longus weight0.20.82.4-0.7-0.7-0.10.6-0.6-1.6-0.31.30.61.2
Bone: elastic displacement0.60.71.8-0.9-0.9-1.0-1.0-0.20.7-0.8-1.3-0.5-0.6
Bone: elastic work1.11.53.0-1.7-1.7-1.5-1.2-1.20.1-1.7-0.80.30.5
Bone: endosteal estimation0.81.73.71.11.11.41.70.9-1.91.01.61.30.7
Bone: endosteal perimeter1.12.44.11.31.31.91.92.0-1.61.90.7-0.9-1.1
Epididymis fat weight0.10.30.80.10.10.40.50.8-0.70.5-0.3-0.9-0.6
Delta time in closed arm before/after self-admin0.80.81.6-1.1-1.1-0.7-0.8-0.71.0-0.6-0.8-1.3-0.3
Delta time in open arm before/after self-admin3.83.88.41.61.62.02.51.3-2.91.62.21.90.8
Diff in mean of infusions in LGA sessions0.30.40.80.60.60.80.90.5-0.70.60.90.10.3
Delay discount exponential model param0.60.62.40.40.40.30.70.0-1.30.11.01.60.6
Extinction: sum of active levers before priming2.93.35.0-2.1-2.1-2.0-2.2-1.72.1-2.0-1.8-0.60.1
Active lever presses in extinction session 61.51.54.4-0.4-0.4-1.0-1.40.11.8-0.5-2.1-1.2-1.5
Bone: final force0.40.72.30.30.30.71.00.2-1.50.21.11.00.6
Bone: final moment0.30.52.00.20.20.50.90.2-1.40.11.01.00.6
Food consumed during 24 hour testing period5.47.411.13.23.23.33.32.4-2.62.82.81.60.7
Glucose0.20.31.5-0.2-0.20.10.5-0.1-1.2-0.10.30.90.3
Heart weight1.11.74.2-1.3-1.3-1.2-1.6-1.12.0-1.2-1.2-1.30.4
Delay discount hyperbolic model param0.70.72.90.40.40.30.7-0.1-1.40.11.11.70.6
Intermittent access intake day 1-15 change1.42.85.02.22.21.91.52.2-0.42.20.2-1.1-1.2
Intermittent access intake escalation0.91.83.21.71.71.41.21.8-0.31.80.1-1.0-0.9
Intermittent access intake escalation 21.61.83.41.81.81.51.21.8-0.41.70.2-0.5-0.9
Intermitt. access day 1 inactive lever presses0.20.62.80.50.5-0.0-0.30.70.70.3-1.2-0.5-1.7
Intermitt. access day 15 inactive lever presses0.20.40.8-0.6-0.6-0.9-0.6-0.7-0.2-0.80.10.80.6
Intermitt. access escalation Index0.60.81.7-0.7-0.7-1.0-1.2-0.51.3-0.9-1.3-0.4-0.3
Intermittent access day 1 total infusions1.42.34.0-1.9-1.9-1.8-1.4-2.00.3-2.0-0.31.11.1
Intermittent access day 15 total infusions0.30.40.7-0.7-0.7-0.8-0.8-0.60.6-0.7-0.5-0.50.0
Intermittent access terminal intake (last 3 days)0.30.40.8-0.7-0.7-0.9-0.8-0.70.4-0.7-0.5-0.1-0.1
Intermittent access total infusions0.60.71.2-1.0-1.0-1.1-0.8-1.10.1-1.1-0.20.60.5
Intermittent access day 1 locomotion1.82.34.1-1.7-1.7-1.9-1.7-1.70.9-2.0-1.01.20.8
Intermittent access day 15 total locomotion0.61.01.6-1.1-1.1-1.1-0.7-1.3-0.3-1.20.21.21.2
Intermittent access total locomotion1.72.03.3-1.5-1.5-1.5-1.0-1.8-0.3-1.70.31.81.6
Intermittent access standard deviation0.51.12.11.31.30.90.61.40.11.3-0.3-1.2-1.2
Left kidney weight1.04.77.82.22.22.82.62.7-1.62.81.0-1.7-1.1
Right kidney weight0.94.37.61.71.72.62.82.4-2.42.61.7-1.1-0.4
Cocaine induced anxiety0.71.02.3-0.7-0.7-0.9-1.2-0.31.4-0.7-1.5-1.1-1.1
Post-drug Anxiety0.40.40.6-0.6-0.6-0.7-0.8-0.50.8-0.7-0.6-0.6-0.1
Baseline Anxiety0.50.62.00.20.20.70.9-0.1-1.00.41.40.41.2
Tail length2.59.616.94.04.03.52.94.1-1.03.80.7-1.7-2.6
Length with tail1.25.29.92.42.42.72.72.9-1.93.10.9-1.1-1.7
Length without tail0.20.63.4-0.3-0.30.30.90.1-1.90.30.80.80.6
Times rat made contact with spout0.00.00.20.20.2-0.0-0.2-0.10.4-0.0-0.00.10.3
Lifetime Intake0.40.40.9-0.8-0.8-0.9-0.7-0.80.2-0.9-0.30.40.2
Liver weight, left0.40.71.10.80.80.80.91.1-0.81.0-0.10.0-1.0
Liver weight, right0.61.02.20.90.91.11.11.5-1.11.2-0.20.1-1.3
Locomotor activity1.21.96.50.00.00.00.5-0.9-1.5-0.91.72.62.3
Locomotor testing distance1.01.86.10.10.1-0.10.4-1.0-1.3-1.01.82.52.3
Locomotor testing rearing1.12.34.71.51.51.61.80.8-1.60.92.21.11.5
Locomotion in novel chamber1.11.44.6-0.6-0.6-0.00.4-1.0-1.1-0.61.51.82.1
Locomotion in novel chamber post-restriction0.30.52.41.01.00.10.10.5-0.2-0.1-0.11.5-0.2
Fecal boli incidents, locomotor time 11.52.23.81.71.71.81.71.8-1.12.00.5-0.5-1.4
Change in fecal boli incidents, locomotor task0.60.62.60.40.4-0.0-0.60.51.60.0-1.0-1.1-0.8
Time >=10cm from walls, locomotor time 10.20.20.50.70.70.40.10.10.50.30.6-0.70.3
Bouts of movement, locomotor time 10.50.51.6-0.2-0.2-0.5-0.70.11.1-0.1-1.0-1.3-0.9
Total resting periods, locomotor time 10.91.12.6-0.5-0.5-0.8-1.1-0.01.5-0.3-1.4-1.6-1.1
Rest time, locomotor task time 10.60.71.8-0.7-0.7-0.8-0.8-0.20.8-0.4-1.1-1.3-0.9
Distance moved, locomotor task time 10.60.93.2-0.1-0.1-0.10.3-0.6-0.9-0.41.11.81.7
Vertical activity count, locomotor time 11.53.56.21.81.82.22.51.2-2.21.72.41.21.1
Time >=10cm from walls, locomotor time 20.30.51.3-0.8-0.8-0.8-0.6-1.10.1-0.80.10.50.5
Bouts of movement, locomotor time 20.40.72.0-0.7-0.7-0.9-1.1-0.61.4-0.8-0.8-0.60.1
Total resting periods, locomotor time 20.20.31.1-0.3-0.3-0.5-0.7-0.41.0-0.4-0.4-0.60.1
Rest time, locomotor task time 20.30.40.70.80.80.70.60.5-0.20.70.6-0.5-0.2
Distance moved, locomotor task time 21.51.83.1-1.8-1.8-1.6-1.1-1.7-0.1-1.6-0.01.01.3
Vertical activity count, locomotor time 21.21.64.50.60.61.21.70.6-2.10.91.61.11.1
Light reinforcement 17.017.228.14.84.85.35.34.4-4.14.63.41.0-0.4
Light reinforcement 28.012.419.24.24.24.34.43.6-3.63.93.01.1-0.3
Bone: marrow area0.81.83.71.11.11.41.70.8-1.90.91.71.30.8
Bone: maximum diameter0.40.72.6-0.1-0.10.50.51.0-0.40.9-0.5-1.6-1.2
Bone: maximum force0.20.41.90.00.00.40.80.1-1.40.10.70.90.4
Bone: maximum moment0.20.31.7-0.1-0.10.30.70.1-1.3-0.00.60.80.4
Mean time between licks in bursts0.10.20.6-0.0-0.00.1-0.00.60.30.4-0.4-0.8-0.3
Mean num. licks in bursts0.40.51.4-0.4-0.4-0.8-1.0-0.61.2-0.7-0.90.0-0.6
Cd content in liver1.82.05.4-2.3-2.3-1.5-1.2-1.40.4-1.2-0.4-0.71.0
Co content in liver3.84.46.7-2.4-2.4-2.4-2.5-1.42.0-1.9-2.6-1.7-0.8
Cu content in liver0.20.30.7-0.8-0.8-0.5-0.2-0.5-0.4-0.6-0.3-0.20.3
Fe content in liver1.11.45.30.70.7-0.0-0.50.61.20.4-2.1-0.8-2.3
K content in liver1.11.02.6-0.9-0.9-1.3-1.1-1.00.2-1.6-1.10.90.3
Mg content in liver0.80.82.1-0.7-0.7-1.1-1.0-0.60.3-1.5-1.40.5-0.4
Mn content in liver0.30.40.90.50.50.70.80.9-1.00.60.4-0.1-0.1
Na content in liver0.20.20.90.60.60.20.20.1-0.10.0-0.00.9-0.1
Rb content in liver0.10.10.30.50.50.40.30.6-0.30.3-0.2-0.1-0.2
Se content in liver1.21.46.10.80.80.60.41.3-0.00.7-1.6-1.1-2.5
Sr content in liver0.70.61.2-1.1-1.1-0.9-0.7-0.8-0.2-1.10.20.40.5
Zn content in liver1.01.12.2-1.5-1.5-1.2-1.0-1.20.4-1.4-0.6-0.30.4
Bone: minimum diameter1.42.64.31.71.72.02.11.8-1.81.81.30.4-0.2
Time in familiar zone, hab. session 10.60.62.20.50.50.70.30.90.61.0-0.2-1.5-0.6
Time in novel zone, hab. session 11.31.32.8-0.8-0.8-1.3-1.2-1.50.6-1.7-0.11.51.0
Total zone transitions, hab. session 10.60.81.70.90.90.80.90.4-1.00.31.31.00.9
Total locomotion distance, hab. session 10.40.62.40.60.60.30.5-0.1-0.8-0.11.01.61.0
Locomotion velocity, hab. session 10.70.92.70.80.80.70.90.2-1.30.11.31.60.9
Time in familiar zone, hab. session 21.01.01.91.21.21.31.11.4-0.61.30.4-0.0-0.4
Time in novel zone, hab. session 22.22.24.4-1.9-1.9-1.7-1.3-2.10.4-1.80.20.41.5
Total zone transitions, hab. session 20.60.71.41.21.21.01.01.1-0.70.50.60.20.4
Total locomotion distance, hab. session 20.70.92.10.80.80.81.10.6-1.50.21.11.20.8
Locomotion velocity, hab. session 20.81.02.50.90.91.01.20.6-1.60.31.11.30.7
Novel to familiar place preference ratio0.70.82.1-0.7-0.7-0.8-0.6-1.20.1-1.00.51.01.5
Novelty place preference0.91.03.1-0.6-0.6-0.7-0.5-1.3-0.1-0.90.81.31.7
Time in novel zone, NPP test1.21.22.7-0.8-0.8-1.1-0.9-1.60.4-1.30.41.31.6
Total zone transitions, NPP test0.91.42.61.11.11.51.61.5-1.61.10.7-0.1-0.1
Total locomotion distance, NPP test0.20.20.60.40.40.50.60.5-0.80.10.40.30.3
Locomotion velocity, NPP test0.40.62.10.50.50.91.20.9-1.50.60.70.10.1
Intraocular pressure2.13.15.1-2.3-2.3-2.1-2.1-1.81.6-1.8-1.3-0.90.1
Delta distance traveled before/after self-admin0.10.10.30.40.40.20.20.3-0.3-0.10.10.60.3
Delta ambulatory time before/after self-admin0.40.51.41.21.20.70.51.2-0.20.60.00.2-0.1
Parametrial fat weight0.51.23.10.70.71.21.51.2-1.71.21.2-0.00.0
Pavlov. Cond. lever latency0.30.41.90.10.10.30.4-0.3-0.5-0.01.00.91.4
Pavlov. Cond. magazine entry latency0.60.81.8-0.6-0.6-1.1-1.3-0.61.3-0.8-1.0-0.4-0.7
Pavlov. Cond. change in total contacts0.60.72.90.40.40.1-0.10.90.50.5-1.0-1.0-1.7
Pavlov. Cond. index score0.70.91.8-0.6-0.6-1.0-1.2-0.31.1-0.6-1.3-0.8-1.2
Pavlov. Cond. latency score0.40.51.3-0.4-0.4-0.6-0.70.00.7-0.3-1.0-0.8-1.1
Pavlov. Cond. lever contacts0.60.71.6-0.4-0.4-0.7-0.9-0.10.9-0.5-1.2-0.8-1.3
Pavlov. Cond. magazine entry number1.41.83.41.21.21.71.81.0-1.61.41.50.40.9
Pavlov. Cond. intertrial magazine entries0.91.03.8-0.3-0.30.30.10.80.10.6-1.5-1.9-1.8
Pavlov. Cond. lever-magazine prob. diff.0.91.22.1-0.9-0.9-1.3-1.4-0.51.2-0.9-1.4-0.6-1.1
Pavlov. Cond. response bias1.31.63.4-0.7-0.7-1.4-1.7-0.71.8-1.1-1.7-0.7-1.3
Pavlov. Cond. lever latency0.10.10.4-0.7-0.7-0.2-0.0-0.4-0.30.10.3-0.20.2
Pavlov. Cond. magazine entry latency0.10.10.80.10.10.20.20.40.00.5-0.1-0.9-0.2
Pavlov. Cond. change in total contacts0.20.41.10.30.3-0.2-0.60.21.1-0.4-1.0-0.7-0.7
Pavlov. Cond. index score0.10.20.40.40.40.0-0.20.40.6-0.0-0.7-0.4-0.5
Pavlov. Cond. latency score0.20.20.40.50.50.1-0.10.50.50.1-0.7-0.5-0.6
Pavlov. Cond. lever contacts0.10.10.50.70.70.30.20.40.20.1-0.10.10.0
Pavlov. Cond. magazine entry number0.10.10.7-0.2-0.2-0.1-0.0-0.3-0.2-0.20.50.80.5
Pavlov. Cond. intertrial magazine entries1.31.93.41.71.71.81.71.7-1.21.51.00.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.30.3-0.1-0.30.20.6-0.1-0.7-0.4-0.4
Pavlov. Cond. response bias0.00.00.10.30.30.1-0.00.20.1-0.2-0.3-0.1-0.1
Time in closed arm before self-admin0.60.81.81.41.40.5-0.01.10.80.6-0.70.2-1.0
Time in closed arm after self-admin0.50.62.20.10.10.2-0.30.31.10.4-0.8-1.5-1.1
Time in open arm before self-admin0.80.92.2-1.2-1.2-0.8-0.9-0.81.0-0.7-0.7-1.50.0
Time in open arm after self-admin0.30.30.8-0.4-0.4-0.30.2-0.4-0.9-0.30.60.70.8
Bone: periosteal estimation0.91.94.11.11.11.61.91.2-2.01.31.60.50.4
Bone: periosteal perimeter0.91.52.90.60.61.41.51.7-1.31.50.3-1.5-0.9
Bone: post-yield work0.60.91.60.90.91.01.10.3-1.10.71.31.20.6
Progressive ratio test 1 active lever presses0.80.91.6-1.2-1.2-1.2-0.8-1.3-0.1-1.3-0.00.90.7
Progressive ratio test 1 breakpoint0.81.01.7-1.3-1.3-1.2-0.9-1.3-0.0-1.3-0.00.80.7
Progressive ratio test 1 inactive lever presses0.20.30.7-0.6-0.6-0.9-0.7-0.50.1-0.7-0.50.2-0.3
Progressive ratio test 2 active lever presses0.50.61.3-1.1-1.1-0.9-0.6-1.10.1-0.90.10.20.6
Progressive ratio test 2 breakpoint0.60.71.4-1.1-1.1-0.9-0.7-1.20.1-0.90.10.20.7
Progressive ratio test 2 inactive lever presses0.81.32.3-1.5-1.5-1.5-1.3-1.50.6-1.4-0.30.20.6
Incentive Sensitization - Responses0.10.10.7-0.3-0.3-0.00.0-0.30.10.10.3-0.80.2
Incentive Sensitization - Breakpoint0.10.10.6-0.2-0.20.10.1-0.20.00.20.3-0.80.2
Sum of active levers in priming session hrs 5-60.40.41.3-0.2-0.20.10.3-0.4-0.7-0.30.81.11.1
Progressive ratio0.71.12.10.80.81.31.50.7-1.21.21.4-0.30.6
Food seeking constrained by brief footshock1.82.24.11.81.81.71.52.0-0.91.90.4-0.6-1.1
Seeking ratio, punishment vs. effort0.30.41.30.80.80.30.31.0-0.20.6-0.40.0-1.1
Retroperitoneal fat weight0.41.56.60.30.31.31.81.2-2.61.01.1-0.00.3
Reaction time number correct1.01.93.3-1.3-1.3-1.4-1.6-0.71.7-0.9-1.8-1.8-0.9
Reaction time mean minus median0.30.71.5-1.2-1.2-1.0-0.8-0.70.4-0.4-0.5-0.9-0.2
Reaction time mean minus median AUC0.51.22.8-1.7-1.7-1.5-1.2-1.10.4-0.8-0.8-0.5-0.1
Reaction time num false alarms1.01.44.0-2.0-2.0-1.1-0.8-1.30.2-0.9-0.2-0.90.7
Reaction time num false alarms AUC1.01.53.4-1.8-1.8-1.2-1.2-1.20.9-1.1-0.7-1.20.3
Reaction time trials correct on left1.01.93.3-1.3-1.3-1.4-1.6-0.71.7-0.9-1.8-1.8-0.9
Reaction time trials on left1.01.93.0-1.4-1.4-1.4-1.6-0.81.6-1.0-1.7-1.7-0.8
Reaction time mean2.13.37.4-2.7-2.7-2.3-1.8-2.20.7-1.7-0.7-0.00.8
Reaction time mean AUC2.03.16.9-2.6-2.6-2.2-1.8-2.20.7-1.7-0.60.20.8
Median of all reaction times2.53.67.7-2.8-2.8-2.3-1.9-2.40.8-1.9-0.80.30.9
Reaction time omissions0.81.13.1-1.8-1.8-0.9-0.5-1.3-0.3-0.50.6-0.71.0
Reaction time false alarm rate0.20.30.8-0.9-0.9-0.4-0.3-0.60.1-0.50.1-0.20.5
Reaction time premature initiation rate3.95.410.02.92.92.82.53.2-1.12.90.7-0.6-1.5
Reaction time premature initiations1.62.95.92.02.01.91.52.4-0.32.2-0.1-1.3-1.6
Std. dev. reaction times0.50.82.1-1.5-1.5-1.2-0.9-1.00.4-0.5-0.3-0.70.2
Reaction time trials completed1.01.93.0-1.4-1.4-1.4-1.6-0.81.6-1.0-1.7-1.7-0.8
Reaction time trials AUC1.01.92.7-1.4-1.4-1.5-1.6-0.91.6-1.1-1.6-1.6-0.6
Run reversals in cocaine runway, females1.61.64.4-1.0-1.0-0.20.6-1.1-2.1-0.71.51.61.6
Run reversals in cocaine runway, males0.40.40.9-0.3-0.3-0.7-0.8-0.70.9-0.60.1-0.60.5
Latency to leave start box in cocaine runway0.91.02.6-0.6-0.6-0.00.5-0.8-1.5-0.31.51.31.6
Latency to leave start box in cocaine runway, F1.01.22.6-0.9-0.9-0.8-0.3-1.4-0.7-1.20.91.61.4
Latency to leave start box in cocaine runway, M1.11.02.40.50.51.11.40.8-1.51.21.30.20.7
Std. dev. time between licks in bursts0.81.02.11.11.11.31.11.4-0.51.40.6-0.6-0.2
Total sessions with >9 infusions2.22.64.7-1.6-1.6-2.2-2.2-1.31.5-1.9-1.90.1-0.6
Short access day 1 total inactive lever presses0.20.21.1-0.1-0.1-0.30.2-0.2-1.0-0.20.41.0-0.1
Short access day 10 total inactive lever presses0.41.02.31.41.40.90.51.5-0.00.9-0.60.2-1.3
Short access day 1 total infusions2.73.55.6-1.9-1.9-2.4-2.4-1.51.8-1.9-2.3-0.9-1.3
Short access day 10 total infusions0.50.71.5-0.8-0.8-1.2-1.0-0.80.3-1.2-0.60.90.3
Short access total infusions0.81.12.2-1.1-1.1-1.5-1.3-1.00.7-1.3-1.00.1-0.2
Short access day 1 locomotion2.83.56.2-2.2-2.2-2.5-2.3-2.01.4-2.2-1.7-0.0-0.4
Short access day 10 total locomotion1.12.03.5-1.3-1.3-1.8-1.9-1.31.4-1.9-1.31.00.7
Short access total locomotion3.03.66.3-2.0-2.0-2.5-2.4-1.91.6-2.4-1.80.80.3
One hour access (0.3 mA shock)0.40.40.8-0.9-0.9-0.8-0.6-0.90.2-0.7-0.00.10.6
Compulsive drug intake1.01.23.50.10.1-0.4-1.00.51.7-0.1-1.9-1.3-1.5
One hour access (shock baseline)0.50.72.0-0.9-0.9-0.40.0-1.1-0.7-0.51.00.71.4
Social response proportion0.50.61.2-0.9-0.9-0.20.2-0.8-0.8-0.30.90.41.1
Social responses0.20.31.7-0.2-0.20.20.3-0.1-0.4-0.10.90.31.3
Social time0.40.50.90.80.80.3-0.20.91.00.5-0.5-0.8-0.9
Soleus weight0.10.20.7-0.3-0.3-0.00.1-0.4-0.3-0.30.8-0.10.8
Bone: stiffness0.91.54.50.40.40.91.5-0.0-2.10.41.71.71.0
Tibialis anterior weight0.20.73.7-0.9-0.9-0.6-0.6-0.10.5-0.2-0.8-1.9-0.6
Time to tail flick, vehicle, before self-admin0.30.30.60.70.70.80.60.4-0.10.70.6-0.00.0
Time to tail flick, vehicle, after self-admin0.81.02.20.50.51.41.50.3-1.01.31.50.10.7
Time to tail flick, test, before self-admin1.31.42.9-1.7-1.7-1.4-0.9-1.6-0.1-1.20.10.40.8
Time to tail flick, test, after self-admin0.10.10.30.30.30.30.30.3-0.10.50.4-0.40.1
Delta time to tail flick, vehicle, before/after SA0.20.20.50.10.10.50.60.2-0.60.70.4-0.2-0.1
Delta time to tail flick, test, before/after SA0.30.31.10.50.50.2-0.10.70.70.4-0.5-1.0-0.4
Tibia length0.10.21.30.40.40.20.10.4-0.10.2-0.70.0-1.1
Ambulatory time before self-admin0.81.22.0-1.2-1.2-1.4-1.3-1.40.7-1.4-0.50.70.2
Ambulatory time after self-admin0.10.10.20.10.1-0.5-0.5-0.20.4-0.5-0.20.40.2
Bone: tissue strength0.80.81.6-1.2-1.2-1.0-0.8-0.50.3-0.5-1.3-0.6-0.7
Total heroin consumption0.20.20.9-0.3-0.3-0.20.0-0.3-0.5-0.50.50.51.0
Bone: trabecular number2.64.210.73.33.32.01.02.41.21.9-0.4-0.9-2.0
Bone: trabecular spacing1.92.66.3-2.5-2.5-1.7-1.0-2.0-0.6-1.5-0.00.61.5
Bone: trabecular thickness0.50.71.91.41.40.90.70.7-0.30.40.70.6-0.0
Bone: trabecular tissue density1.72.55.2-1.8-1.8-1.3-0.7-2.3-0.7-1.70.81.72.1
Water consumed over 24 hours0.50.61.41.21.20.80.70.5-0.40.40.80.90.7
Number of responses in last shaping day2.12.35.1-0.9-0.9-1.3-1.7-0.42.1-0.7-2.3-1.9-1.8