Btaf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IC	mRNA stability	Btaf1	0.11	0.08	1.9e-03	0.05	0.05	0.05	0.04	4.2e-03	3.9e-03	4.1e-03	5.8e-03
2	Brain	alternative TSS	XM_039085850.2	0.04	0.03	6.2e-03	0.02	0.01	0.01	0.01	6.5e-03	6.2e-02	4.0e-02	6.1e-02
3	PL	alternative TSS	XM_039085850.2	0.03	0.02	7.4e-04	0.03	0.02	0.02	0.02	6.1e-04	2.0e-03	4.4e-03	2.4e-03
4	NAcc	mRNA stability	Btaf1	0.01	0.01	9.4e-03	0.01	0.01	0	0	1.0e-02	3.4e-02	2.1e-01	5.4e-02
5	PL	gene expression	Btaf1	0.02	0.01	9.1e-03	0	0.01	0.01	0	8.8e-02	6.9e-02	6.4e-02	2.4e-01
6	NAcc	gene expression	Btaf1	0.02	0.01	7.7e-04	0.03	0.02	0.01	0.02	4.9e-05	8.1e-04	2.4e-02	3.3e-04
7	Brain	mRNA stability	Btaf1	0.13	0.08	2.1e-10	0.1	0.11	0.1	0.12	5.5e-10	4.4e-10	4.9e-10	4.5e-11
8	IC	gene expression	Btaf1	0.12	0.07	5.2e-05	0.12	0.12	0.11	0.12	7.3e-06	1.3e-05	2.8e-05	8.6e-06
9	Adipose	gene expression	Btaf1	0.06	0.04	2.1e-05	0.04	0.04	0.02	0.03	7.7e-05	8.8e-05	1.3e-03	2.3e-04
10	Brain	gene expression	Btaf1	0.03	0.02	4.4e-03	0.02	0.01	0.01	0.01	7.2e-03	5.1e-02	2.7e-02	3.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	7.1	12.2	18.2	-3.4	-3.7	-3.7	-4.3	-3.9	-3.6	-3.3	-4.3	2.1	-1.9
Area under the delay curve	0.2	0.3	0.5	0.6	0.7	0.7	0.6	0.6	0.7	0.3	0.3	-0.0	0.0
BMI with tail	0.1	0.4	0.9	-0.6	-0.6	-0.7	-0.9	-0.7	-0.9	-0.6	-0.5	0.0	-0.0
BMI without tail	0.0	0.1	0.2	-0.5	-0.2	-0.2	0.0	0.0	-0.1	-0.3	0.2	0.2	-0.2
Body weight	1.4	6.0	10.2	-3.2	-2.6	-2.8	-2.0	-2.3	-2.5	-2.7	-1.4	2.4	-2.3
Weight adjusted by age	0.1	0.2	0.6	0.6	0.4	0.5	-0.5	-0.3	0.4	0.0	-0.8	-0.5	0.3
Bone surface	3.7	6.7	9.4	-2.9	-3.0	-3.1	-3.0	-2.8	-2.5	-2.2	-3.1	1.3	-1.1
Bone volume	5.8	10.4	13.9	-3.5	-3.5	-3.6	-3.6	-3.5	-3.2	-3.1	-3.7	2.1	-2.0
Breakpoint value in progressive ratio session	0.4	0.5	1.3	-0.4	-0.3	-0.4	-0.6	-0.7	-0.4	-0.9	-0.1	1.1	-1.1
Number of licking bursts	1.7	2.7	4.7	1.9	2.2	2.0	1.7	1.6	1.6	1.3	1.6	-1.0	1.3
Context. condit. distance diff. score	3.0	3.7	5.7	-1.9	-1.8	-1.8	-1.6	-1.9	-1.8	-2.1	-1.6	2.1	-2.4
Locomotion velocity, session 1	4.1	4.5	7.7	2.1	2.1	2.0	1.6	2.1	1.6	2.1	1.7	-2.7	2.8
Locomotion distance, session 1	0.3	0.4	0.8	0.7	0.8	0.7	0.3	0.5	0.6	0.6	0.6	-0.7	0.9
Locomotion velocity, session 2	1.0	1.2	1.7	1.0	1.1	1.0	0.9	1.1	0.9	1.2	1.1	-1.2	1.3
Locomotion distance, session 2	0.2	0.3	0.8	0.4	0.7	0.5	0.6	0.6	0.8	0.4	0.9	-0.0	0.2
Locomotion velocity, session 3	0.2	0.3	0.5	-0.7	-0.6	-0.5	-0.2	-0.3	-0.7	-0.5	-0.3	0.6	-0.7
Locomotion distance, session 3	1.2	1.3	2.9	-1.3	-1.1	-1.1	-0.3	-0.8	-1.1	-1.2	-0.4	1.6	-1.7
Stereotopy head waving bouts, day 3	0.2	0.3	1.0	0.4	0.1	0.3	0.1	0.4	0.2	0.6	0.1	-1.0	0.9
Stereotopy head waving duration, day 3	0.2	0.3	0.9	0.5	0.3	0.4	-0.1	0.3	0.2	0.5	-0.1	-0.9	0.9
Locomotion velocity, session 7	1.2	1.3	2.7	-0.9	-0.6	-0.6	-0.9	-1.1	-0.7	-1.4	-0.9	1.6	-1.6
Locomotion distance, session 7	1.2	1.5	2.7	-1.0	-0.8	-0.9	-1.0	-1.2	-0.9	-1.5	-1.1	1.6	-1.6
Stereotopy head waving bouts, day 7	0.3	0.3	0.6	0.2	0.1	0.2	0.7	0.7	0.4	0.7	0.6	-0.8	0.6
Stereotopy head waving duration, day 7	0.2	0.2	0.8	-0.1	-0.2	-0.2	0.4	0.5	0.1	0.6	0.4	-0.9	0.7
Locomotion velocity, session 8	0.3	0.3	0.5	-0.6	-0.5	-0.6	-0.7	-0.7	-0.7	-0.6	-0.5	0.5	-0.5
Locomotion distance, session 8	0.7	1.0	2.5	-0.9	-0.5	-0.7	-0.8	-1.0	-0.5	-1.2	-0.7	1.5	-1.6
Degree of sensitization distance	0.2	0.2	0.5	0.6	0.7	0.6	-0.2	-0.1	0.5	-0.2	-0.2	0.1	0.0
Degree of sensitization stereotypy	0.1	0.1	0.2	-0.3	-0.4	-0.4	0.3	0.2	-0.1	0.4	0.3	-0.4	0.2
Conditioned locomotion	0.7	0.8	1.3	-0.8	-0.7	-0.7	-1.0	-1.0	-0.9	-1.0	-1.1	0.9	-0.8
Cocaine response after cond. corrected	0.0	0.0	0.1	0.1	-0.1	-0.1	-0.0	0.0	0.1	0.1	-0.1	-0.2	0.2
Cocaine response after cond. not corrected	0.1	0.1	0.3	-0.4	-0.4	-0.5	-0.1	-0.2	-0.2	-0.4	-0.2	0.5	-0.5
Cocaine response before conditioning	0.2	0.2	0.5	-0.2	0.0	-0.1	0.6	0.1	0.2	-0.2	0.7	0.7	-0.7
Saline control response	0.2	0.3	0.9	0.1	0.2	0.3	-0.2	-0.5	0.1	-0.6	-0.4	0.9	-0.8
Bone: connectivity density	3.2	4.9	9.2	-2.0	-2.4	-2.4	-3.0	-2.6	-2.2	-1.9	-2.8	0.8	-0.8
Bone: cortical apparent density	1.7	2.3	3.5	1.7	1.6	1.6	1.2	1.5	1.9	1.5	1.2	-1.5	1.5
Bone: cortical area	4.7	7.2	10.3	-3.2	-2.9	-2.9	-2.1	-2.5	-2.5	-3.0	-2.1	2.7	-2.6
Bone: cortical porosity	0.0	0.0	0.1	0.3	0.4	0.4	0.1	0.1	0.2	0.2	0.1	0.0	0.1
Bone: cortical porosity	0.0	0.0	0.1	-0.2	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.1	0.3	-0.3
Bone: cortical thickness	0.8	1.3	2.5	-1.5	-1.1	-1.1	-0.4	-0.9	-0.7	-1.5	-0.4	1.6	-1.4
Bone: cortical thickness	0.2	0.2	0.4	0.3	0.6	0.6	0.5	0.4	0.7	0.1	0.3	0.2	-0.0
Bone: cortical tissue density	1.9	2.5	3.7	1.8	1.7	1.7	1.2	1.5	1.9	1.6	1.2	-1.6	1.6
Condit. Reinf. active minus inactive responses	0.6	0.7	1.5	0.7	0.9	0.9	1.2	1.0	0.8	0.7	1.1	-0.3	0.3
Condit. Reinf. active-inactive response ratio	1.4	1.5	2.0	1.1	1.0	1.1	1.4	1.4	1.0	1.3	1.3	-1.3	1.2
Condit. Reinf. active responses	0.2	0.2	0.8	-0.4	-0.1	-0.1	0.2	-0.0	-0.3	-0.5	0.1	0.8	-0.9
Condit. Reinf. inactive responses	1.5	1.8	3.0	-1.4	-1.1	-1.1	-1.1	-1.3	-1.2	-1.5	-1.2	1.7	-1.7
Incentive salience index mean	0.6	0.8	1.9	0.6	1.0	1.0	1.4	1.1	0.8	0.4	1.3	0.1	-0.1
Condit. Reinf. lever presses	0.9	1.3	2.3	1.0	1.3	1.4	1.5	1.3	1.1	0.6	1.5	-0.2	0.2
Condit. Reinf. active minus inactive responses	0.6	0.7	2.1	-0.8	-0.6	-0.5	-0.4	-0.7	-0.4	-1.0	-0.4	1.4	-1.4
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	-0.1	0.1	0.2	0.0	-0.1	0.2	-0.2	-0.2	0.5	-0.5
Condit. Reinf. active responses	1.7	2.4	3.4	-1.8	-1.6	-1.5	-1.1	-1.4	-1.3	-1.6	-1.3	1.8	-1.8
Condit. Reinf. inactive responses	1.5	2.0	3.0	-1.7	-1.7	-1.7	-1.0	-1.2	-1.6	-1.4	-1.0	1.2	-1.3
Condit. Reinf. lever presses	0.1	0.1	0.3	-0.3	-0.2	-0.2	-0.1	-0.2	-0.4	-0.2	-0.5	0.2	-0.1
Condit. Reinf. lever reinforcers received	1.0	1.4	2.3	-1.3	-1.2	-1.1	-0.8	-1.1	-1.0	-1.3	-1.0	1.5	-1.5
Conditioned reinforcement - actives	0.9	1.5	2.4	-1.5	-1.4	-1.3	-1.5	-1.3	-1.4	-1.2	-0.7	0.8	-0.6
Conditioned reinforcement - inactives	0.7	1.1	2.1	-1.1	-1.1	-1.1	-1.4	-1.2	-1.1	-1.0	-0.9	0.6	-0.5
Conditioned locomotion	0.8	1.0	1.9	-1.1	-1.3	-1.2	-1.4	-1.0	-1.3	-0.7	-0.6	0.2	0.0
Patch foraging indifference point 0 sec	0.1	0.2	0.7	-0.3	-0.1	-0.1	0.5	0.3	-0.1	0.5	0.9	-0.6	0.7
Patch foraging indifference point AUC	0.6	0.9	2.1	0.8	0.9	0.9	1.2	1.2	0.9	0.8	1.4	-0.4	0.5
Delay disc. indifference point, 0s delay	0.6	0.7	2.3	-0.1	0.1	0.2	-0.3	-0.6	0.3	-1.1	-0.6	1.5	-1.5
Delay disc. indifference point, 16s delay	0.1	0.1	0.3	-0.3	-0.3	-0.3	-0.3	-0.2	-0.4	-0.1	-0.6	0.0	-0.0
Delay disc. indifference point, 2s delay	0.3	0.3	0.6	0.8	0.7	0.7	0.0	0.3	0.8	0.5	-0.2	-0.4	0.4
Delay disc. indifference point, 24s delay	0.8	0.9	2.5	0.7	0.9	1.0	1.6	1.3	0.8	0.5	1.2	-0.1	0.0
Delay disc. indifference point, 4s delay	0.1	0.1	0.5	0.1	0.3	0.3	0.1	0.0	0.3	-0.3	-0.0	0.7	-0.7
Delay disc. indifference point, 8s delay	2.0	2.4	3.2	1.7	1.8	1.7	1.6	1.6	1.7	1.4	1.3	-1.2	1.2
Indifference point function ln k	0.9	1.7	2.5	-1.5	-1.4	-1.3	-1.2	-1.4	-1.3	-1.1	-1.6	0.9	-1.0
Indifference point function log k	0.9	1.7	2.5	-1.5	-1.4	-1.3	-1.2	-1.4	-1.3	-1.1	-1.6	0.9	-1.0
Patch foraging total patch changes 0 sec	0.1	0.2	0.6	-0.3	-0.2	-0.3	0.4	0.2	-0.2	0.4	0.8	-0.5	0.6
Patch foraging total patch changes 12 sec	1.5	1.9	2.8	1.4	1.3	1.3	1.4	1.5	1.2	1.5	1.7	-1.3	1.3
Patch foraging total patch changes 18 sec	0.2	0.3	0.6	0.5	0.6	0.6	0.5	0.7	0.5	0.6	0.8	-0.5	0.6
Patch foraging total patch changes 24 sec	0.1	0.2	0.6	-0.1	0.2	0.2	0.7	0.5	0.5	0.4	0.8	-0.0	0.1
Patch foraging total patch changes 6 sec	1.1	1.6	3.4	0.8	0.9	0.8	1.6	1.4	0.9	1.4	1.8	-1.3	1.4
Patch foraging time to switch 0 sec	0.6	1.3	2.2	1.5	1.4	1.3	0.9	1.2	1.2	1.1	0.7	-1.0	0.9
Patch foraging water rate 0 sec	0.3	0.5	0.9	-1.0	-0.9	-0.8	-0.6	-0.8	-0.8	-0.7	-0.4	0.7	-0.6
Patch foraging water rate 12 sec	0.4	0.7	1.5	-1.2	-1.1	-1.0	-0.8	-0.8	-1.1	-0.8	-0.4	0.5	-0.5
Patch foraging water rate 18 sec	0.8	1.3	2.0	-1.4	-1.2	-1.3	-0.9	-1.2	-1.1	-1.1	-0.6	1.1	-1.1
Patch foraging water rate 24 sec	1.9	2.6	3.7	-1.8	-1.5	-1.6	-1.1	-1.7	-1.7	-1.8	-1.0	1.9	-1.9
Patch foraging water rate 6 sec	0.1	0.1	0.2	-0.4	-0.4	-0.3	-0.2	-0.3	-0.3	0.1	-0.3	-0.3	0.3
Seeking ratio, delayed vs. immediate footshock	0.0	0.0	0.2	-0.1	0.1	0.0	0.3	0.0	0.1	-0.3	0.2	0.4	-0.3
Distance traveled before self-admin	0.2	0.3	0.5	0.6	0.7	0.7	0.6	0.5	0.7	0.4	0.2	-0.2	0.2
Distance traveled after self-admin	0.3	0.4	1.3	0.6	0.2	0.1	-0.8	-0.4	0.1	0.2	-1.1	-0.8	0.7
Extensor digitorum longus weight	0.8	3.1	7.9	-1.7	-1.4	-1.1	-0.9	-1.5	-1.2	-2.2	-1.1	2.6	-2.8
Bone: elastic displacement	3.8	4.4	6.8	2.4	2.0	2.2	1.3	1.8	1.9	2.6	1.2	-2.5	2.4
Bone: elastic work	2.0	2.6	4.5	1.9	1.6	1.7	0.6	1.1	1.6	2.0	0.5	-2.1	2.0
Bone: endosteal estimation	4.7	10.2	13.4	-3.5	-3.7	-3.6	-3.3	-3.3	-3.4	-2.8	-3.6	2.1	-2.2
Bone: endosteal perimeter	5.0	10.7	13.4	-3.5	-3.7	-3.6	-3.6	-3.5	-3.4	-3.0	-3.6	2.2	-2.2
Epididymis fat weight	1.0	3.5	4.6	-1.7	-1.7	-1.9	-2.1	-2.0	-2.1	-1.9	-2.0	1.5	-1.3
Delta time in closed arm before/after self-admin	0.7	0.6	2.0	0.5	0.6	0.5	1.0	1.1	0.6	0.5	1.4	-0.5	0.4
Delta time in open arm before/after self-admin	0.2	0.2	0.7	0.7	0.6	0.6	-0.1	-0.0	0.6	0.2	-0.9	-0.2	0.2
Diff in mean of infusions in LGA sessions	0.5	0.6	0.9	-0.8	-0.7	-0.7	-0.9	-0.9	-0.7	-0.8	-0.5	0.9	-0.8
Delay discount exponential model param	0.3	0.3	0.5	-0.6	-0.7	-0.7	-0.7	-0.7	-0.6	-0.3	-0.4	0.1	-0.0
Extinction: sum of active levers before priming	0.5	0.5	1.2	-0.8	-0.6	-0.7	-0.1	-0.3	-0.9	-0.9	0.2	1.0	-1.1
Active lever presses in extinction session 6	1.3	1.3	2.9	-0.5	-0.4	-0.4	-1.3	-1.3	-0.5	-1.3	-1.1	1.7	-1.6
Bone: final force	1.7	2.7	4.4	-2.1	-2.0	-1.9	-1.3	-1.6	-1.4	-1.7	-1.4	1.5	-1.4
Bone: final moment	1.4	2.3	3.8	-1.9	-1.9	-1.8	-1.3	-1.5	-1.4	-1.4	-1.4	1.1	-1.0
Food consumed during 24 hour testing period	0.1	0.1	0.4	-0.2	0.0	-0.1	0.6	0.3	-0.2	0.2	0.6	-0.1	0.1
Glucose	0.0	0.1	0.2	-0.4	-0.5	-0.4	0.1	0.0	-0.2	-0.2	0.0	0.2	-0.2
Heart weight	0.4	0.6	2.2	-0.4	-0.5	-0.6	0.3	0.4	-0.5	0.6	0.3	-1.3	1.5
Delay discount hyperbolic model param	0.3	0.4	0.7	-0.7	-0.8	-0.8	-0.6	-0.7	-0.8	-0.5	-0.4	0.2	-0.2
Intermittent access intake day 1-15 change	1.1	2.2	3.9	-1.9	-2.0	-1.8	-1.8	-1.5	-1.9	-1.2	-0.6	0.7	-0.6
Intermittent access intake escalation	1.2	2.5	3.9	-1.9	-2.0	-1.8	-1.8	-1.6	-1.9	-1.3	-0.8	0.9	-0.9
Intermittent access intake escalation 2	0.6	0.7	1.2	-1.1	-1.0	-0.9	-1.1	-0.9	-0.9	-0.8	-0.2	0.6	-0.5
Intermitt. access day 1 inactive lever presses	0.2	0.9	1.2	1.1	1.1	1.1	0.8	0.7	1.1	1.1	0.1	-1.0	1.0
Intermitt. access day 15 inactive lever presses	0.7	1.4	2.8	-1.1	-1.4	-1.4	-1.7	-1.2	-1.3	-0.8	-1.4	0.1	-0.1
Intermitt. access escalation Index	0.3	0.4	1.1	0.7	0.8	0.7	0.8	0.8	0.6	0.2	1.1	-0.0	0.1
Intermittent access day 1 total infusions	1.1	1.7	3.3	-1.3	-1.2	-1.3	-1.8	-1.6	-1.4	-1.2	-1.1	1.0	-0.8
Intermittent access day 15 total infusions	4.1	6.0	8.4	-2.9	-2.9	-2.8	-2.9	-2.6	-2.8	-2.3	-1.4	1.8	-1.7
Intermittent access terminal intake (last 3 days)	2.9	3.8	6.2	-2.3	-2.2	-2.2	-2.5	-2.1	-2.3	-1.7	-1.1	1.2	-1.1
Intermittent access total infusions	2.9	3.5	5.7	-2.1	-2.0	-2.0	-2.4	-2.1	-2.1	-1.8	-1.2	1.4	-1.3
Intermittent access day 1 locomotion	1.2	1.6	2.5	-1.5	-1.3	-1.3	-1.5	-1.6	-1.3	-1.1	-1.1	0.9	-0.8
Intermittent access day 15 total locomotion	1.6	3.0	5.8	-1.9	-2.0	-1.9	-2.4	-1.9	-2.0	-1.3	-1.5	0.8	-0.6
Intermittent access total locomotion	2.3	2.7	5.7	-1.7	-1.7	-1.6	-2.4	-2.0	-1.7	-1.5	-1.6	1.0	-0.9
Intermittent access standard deviation	1.0	2.2	3.4	-1.8	-1.8	-1.8	-1.6	-1.3	-1.8	-1.4	-0.7	1.1	-0.9
Left kidney weight	0.7	3.3	6.4	-2.5	-2.3	-2.3	-1.0	-1.5	-1.8	-1.9	-0.6	1.7	-1.7
Right kidney weight	0.3	1.5	3.6	-1.9	-1.6	-1.6	-0.2	-0.7	-1.1	-1.3	0.3	1.2	-1.2
Cocaine induced anxiety	0.2	0.3	0.6	-0.1	-0.1	-0.1	-0.7	-0.7	-0.1	-0.8	-0.6	0.8	-0.8
Post-drug Anxiety	0.3	0.4	0.9	-0.4	-0.6	-0.7	-0.9	-0.6	-0.6	-0.5	-0.9	0.2	-0.2
Baseline Anxiety	0.3	0.4	0.8	-0.6	-0.9	-0.9	-0.5	-0.3	-0.9	-0.0	-0.7	-0.4	0.4
Tail length	0.6	2.5	5.0	-2.1	-1.6	-1.5	-0.6	-1.1	-0.9	-1.8	-0.8	2.2	-2.2
Length with tail	1.8	7.8	12.7	-3.6	-3.0	-3.0	-2.0	-2.5	-2.5	-3.0	-1.7	3.1	-3.0
Length without tail	3.3	10.8	13.4	-3.7	-3.4	-3.5	-2.9	-3.4	-3.4	-3.5	-2.6	3.1	-3.1
Times rat made contact with spout	0.1	0.2	0.5	0.2	0.5	0.4	-0.2	-0.2	0.1	-0.4	-0.3	0.7	-0.5
Lifetime Intake	2.7	3.3	6.0	-1.9	-1.9	-1.9	-2.4	-2.1	-2.0	-1.7	-1.2	1.3	-1.2
Liver weight, left	1.0	1.6	2.8	-1.7	-1.5	-1.5	-0.7	-1.0	-1.2	-1.3	-1.1	1.2	-1.2
Liver weight, right	1.6	2.8	3.9	-1.9	-1.9	-1.8	-1.8	-1.8	-2.0	-1.6	-1.4	1.1	-1.4
Locomotor activity	0.5	0.9	1.3	1.0	0.9	0.9	0.8	0.8	1.1	1.0	0.6	-1.0	1.0
Locomotor testing distance	1.0	1.8	2.3	1.3	1.3	1.2	1.1	1.2	1.3	1.5	1.3	-1.5	1.5
Locomotor testing rearing	0.1	0.1	0.3	-0.2	-0.1	-0.1	-0.2	-0.4	-0.2	-0.4	-0.2	0.6	-0.6
Locomotion in novel chamber	1.1	1.4	3.1	-0.9	-1.0	-1.0	-1.4	-1.4	-0.9	-0.9	-1.7	1.0	-1.1
Locomotion in novel chamber post-restriction	2.3	3.8	5.6	-2.0	-1.8	-1.7	-1.4	-2.0	-1.7	-2.1	-1.7	2.4	-2.3
Fecal boli incidents, locomotor time 1	0.1	0.2	0.7	-0.1	0.0	-0.1	-0.4	-0.4	0.0	-0.7	-0.1	0.8	-0.8
Change in fecal boli incidents, locomotor task	0.3	0.3	0.7	0.2	0.2	0.3	0.8	0.5	0.4	0.6	0.8	-0.5	0.4
Time >=10cm from walls, locomotor time 1	4.3	4.6	7.7	-2.4	-2.1	-2.1	-1.1	-1.8	-1.8	-2.5	-1.5	2.8	-2.7
Bouts of movement, locomotor time 1	0.3	0.4	0.8	-0.5	-0.4	-0.4	-0.9	-0.8	-0.3	-0.7	-0.2	0.8	-0.5
Total resting periods, locomotor time 1	0.5	0.5	1.1	-0.7	-0.5	-0.5	-1.0	-0.9	-0.3	-0.9	-0.3	1.0	-0.7
Rest time, locomotor task time 1	0.3	0.4	0.7	0.8	0.7	0.7	-0.2	0.2	0.8	0.4	0.4	-0.7	0.7
Distance moved, locomotor task time 1	0.2	0.3	1.0	-0.4	-0.2	-0.1	1.0	0.3	0.1	0.0	0.3	0.7	-0.8
Vertical activity count, locomotor time 1	0.1	0.2	0.6	-0.7	-0.7	-0.6	0.2	-0.2	-0.8	-0.3	-0.1	0.4	-0.4
Time >=10cm from walls, locomotor time 2	0.3	0.4	1.7	-0.5	-0.1	-0.1	0.2	-0.3	0.0	-0.8	-0.0	1.3	-1.3
Bouts of movement, locomotor time 2	1.3	2.1	3.8	1.7	1.9	1.9	0.9	1.1	1.7	1.1	1.6	-0.9	1.1
Total resting periods, locomotor time 2	1.1	2.0	3.7	1.6	1.9	1.8	0.9	1.1	1.7	1.0	1.7	-0.7	1.0
Rest time, locomotor task time 2	0.1	0.1	0.3	0.1	0.2	0.2	-0.3	-0.1	0.2	-0.4	0.2	0.5	-0.5
Distance moved, locomotor task time 2	0.2	0.2	0.7	-0.5	-0.4	-0.3	0.6	0.1	-0.1	-0.1	-0.0	0.6	-0.8
Vertical activity count, locomotor time 2	0.3	0.4	0.8	0.5	0.5	0.4	0.9	0.8	0.4	0.8	0.8	-0.7	0.6
Light reinforcement 1	0.1	0.2	0.9	-0.0	-0.2	-0.1	-0.9	-0.6	0.0	-0.1	-0.9	-0.4	0.4
Light reinforcement 2	3.1	4.7	7.1	2.7	2.4	2.4	1.1	1.8	2.1	2.2	1.2	-2.6	2.5
Bone: marrow area	4.9	10.8	14.1	-3.6	-3.8	-3.7	-3.5	-3.4	-3.5	-2.8	-3.7	2.2	-2.2
Bone: maximum diameter	9.7	18.0	21.4	-4.6	-4.6	-4.6	-4.3	-4.4	-4.4	-4.2	-4.5	3.3	-3.3
Bone: maximum force	2.8	4.9	7.2	-2.7	-2.7	-2.6	-2.1	-2.3	-2.1	-2.1	-2.2	1.7	-1.6
Bone: maximum moment	2.4	4.2	6.6	-2.5	-2.6	-2.5	-2.0	-2.1	-2.1	-1.8	-2.1	1.2	-1.2
Mean time between licks in bursts	0.9	2.3	3.9	1.3	1.2	1.2	1.5	1.7	1.0	1.6	1.6	-1.9	2.0
Mean num. licks in bursts	1.5	2.4	2.8	-1.6	-1.6	-1.6	-1.6	-1.6	-1.4	-1.4	-1.7	1.3	-1.4
Cd content in liver	1.9	2.1	3.4	1.0	1.0	1.0	1.6	1.6	0.8	1.5	1.7	-1.8	1.9
Co content in liver	1.4	1.6	3.8	1.1	0.8	0.8	0.8	1.2	1.1	1.5	1.0	-1.8	2.0
Cu content in liver	2.8	3.3	6.3	2.0	1.6	1.6	1.0	1.5	1.7	2.2	0.9	-2.5	2.5
Fe content in liver	1.4	1.7	3.4	1.1	1.1	1.1	1.5	1.4	1.8	1.4	1.3	-1.1	1.1
K content in liver	0.6	0.6	1.5	1.1	1.2	1.1	0.4	0.4	1.2	0.3	0.4	0.2	-0.1
Mg content in liver	0.7	0.7	1.2	1.1	1.1	1.1	0.7	0.7	1.1	0.8	0.5	-0.6	0.6
Mn content in liver	1.3	1.4	1.9	1.4	1.3	1.2	1.0	1.2	1.2	1.2	1.0	-1.1	1.2
Na content in liver	1.2	1.3	2.7	1.3	1.5	1.3	1.2	1.1	1.7	0.8	1.2	-0.1	0.3
Rb content in liver	0.2	0.2	0.5	-0.5	-0.6	-0.5	-0.3	-0.5	-0.3	-0.3	-0.7	0.4	-0.6
Se content in liver	25.9	30.7	34.3	5.6	5.5	5.4	5.6	5.9	5.7	5.7	5.8	-5.1	5.2
Sr content in liver	1.0	0.8	2.9	0.9	0.6	0.5	0.1	0.6	0.4	1.1	0.2	-1.6	1.7
Zn content in liver	7.6	8.4	12.5	3.1	3.2	3.3	2.9	2.9	3.5	2.6	3.1	-1.9	2.0
Bone: minimum diameter	8.0	14.7	20.4	-4.5	-4.5	-4.4	-3.2	-3.7	-4.1	-3.7	-3.3	3.2	-3.3
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.1	-0.2	-0.2	-0.3	-0.2	-0.1	0.1	-0.4	-0.3	0.5
Time in novel zone, hab. session 1	0.5	0.5	0.8	0.8	0.8	0.8	0.7	0.7	0.9	0.7	0.9	-0.3	0.2
Total zone transitions, hab. session 1	0.0	0.0	0.2	-0.1	-0.1	-0.1	-0.4	-0.2	-0.2	-0.0	-0.4	-0.0	0.0
Total locomotion distance, hab. session 1	0.5	0.7	1.4	1.0	1.2	1.1	0.6	0.7	1.1	0.8	0.5	-0.4	0.5
Locomotion velocity, hab. session 1	0.7	1.0	1.9	1.2	1.4	1.4	0.8	0.9	1.3	0.9	0.6	-0.4	0.5
Time in familiar zone, hab. session 2	0.5	0.5	1.2	0.7	0.6	0.6	0.6	0.7	0.5	0.8	0.5	-1.0	1.1
Time in novel zone, hab. session 2	0.0	0.0	0.1	-0.2	-0.2	-0.2	-0.3	-0.2	-0.2	-0.2	-0.1	0.2	-0.2
Total zone transitions, hab. session 2	0.4	0.5	0.8	0.4	0.5	0.5	0.8	0.8	0.6	0.8	0.8	-0.9	0.9
Total locomotion distance, hab. session 2	0.6	0.8	1.2	0.8	0.9	0.8	0.9	0.9	1.1	0.9	1.0	-0.8	0.8
Locomotion velocity, hab. session 2	0.5	0.7	1.4	0.8	1.0	0.9	0.8	0.9	1.2	0.8	0.9	-0.5	0.5
Novel to familiar place preference ratio	0.7	0.8	1.9	-0.4	-0.6	-0.5	-1.4	-1.1	-0.5	-0.8	-1.0	0.8	-1.0
Novelty place preference	0.8	0.8	2.1	-0.5	-0.7	-0.6	-1.5	-1.2	-0.5	-0.8	-1.2	0.8	-1.0
Time in novel zone, NPP test	0.5	0.6	1.5	-0.3	-0.5	-0.4	-1.2	-0.9	-0.4	-0.6	-1.0	0.6	-0.9
Total zone transitions, NPP test	0.4	0.6	0.9	0.6	0.9	0.8	1.0	0.9	0.7	0.6	0.9	-0.4	0.4
Total locomotion distance, NPP test	1.4	1.8	3.0	1.5	1.7	1.6	1.3	1.4	1.6	1.3	1.2	-0.7	0.9
Locomotion velocity, NPP test	1.1	1.5	2.7	1.3	1.7	1.5	1.2	1.3	1.5	1.1	1.1	-0.5	0.6
Intraocular pressure	0.2	0.3	0.9	-0.6	-0.5	-0.6	-0.7	-0.7	-0.5	-0.2	-0.9	0.3	0.0
Delta distance traveled before/after self-admin	1.8	1.9	3.9	-1.0	-1.4	-1.5	-2.0	-1.6	-1.5	-1.2	-1.7	0.4	-0.5
Delta ambulatory time before/after self-admin	1.9	2.3	4.2	-1.2	-1.5	-1.7	-2.1	-1.8	-1.7	-1.4	-1.9	0.5	-0.7
Parametrial fat weight	0.2	0.6	2.1	-0.0	0.6	0.5	1.2	0.7	0.8	0.1	1.5	0.5	-0.4
Pavlov. Cond. lever latency	0.3	0.4	1.2	-0.2	-0.5	-0.6	-0.6	-0.2	-0.4	0.4	-0.7	-1.1	0.8
Pavlov. Cond. magazine entry latency	0.6	0.8	2.5	0.4	0.7	0.7	1.5	1.1	0.8	0.3	1.6	-0.1	0.2
Pavlov. Cond. change in total contacts	1.2	1.3	3.3	0.7	0.9	0.9	1.8	1.4	0.9	0.8	1.8	-0.5	0.7
Pavlov. Cond. index score	0.4	0.5	1.4	0.1	0.5	0.6	1.1	0.6	0.5	-0.3	1.2	0.8	-0.6
Pavlov. Cond. latency score	0.4	0.5	1.3	0.0	0.5	0.5	1.0	0.4	0.4	-0.5	1.0	1.1	-0.9
Pavlov. Cond. lever contacts	0.4	0.5	1.3	0.4	0.7	0.8	1.0	0.6	0.6	-0.0	1.1	0.7	-0.5
Pavlov. Cond. magazine entry number	0.3	0.4	1.5	-0.1	-0.4	-0.4	-1.1	-0.8	-0.4	-0.1	-1.2	0.1	-0.2
Pavlov. Cond. intertrial magazine entries	0.5	0.6	0.9	-0.8	-0.6	-0.7	-0.7	-0.8	-0.7	-0.8	-0.9	1.0	-0.9
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.7	2.1	0.4	0.8	0.8	1.4	0.9	0.8	0.0	1.5	0.5	-0.4
Pavlov. Cond. response bias	0.9	1.1	2.6	0.7	0.9	0.9	1.6	1.3	0.9	0.7	1.6	-0.5	0.7
Pavlov. Cond. lever latency	0.1	0.1	0.4	-0.1	-0.1	-0.1	-0.2	-0.4	-0.0	-0.3	-0.0	0.6	-0.6
Pavlov. Cond. magazine entry latency	0.9	1.1	1.7	0.9	1.2	1.0	1.3	1.3	0.9	0.8	1.3	-0.7	0.8
Pavlov. Cond. change in total contacts	0.1	0.1	0.3	0.2	0.3	0.3	0.5	0.4	0.2	0.0	0.2	0.2	-0.2
Pavlov. Cond. index score	0.0	0.0	0.2	0.0	0.2	0.1	0.4	0.4	-0.1	-0.1	0.2	0.0	0.0
Pavlov. Cond. latency score	0.0	0.0	0.1	-0.1	0.1	-0.0	0.2	0.2	-0.1	-0.1	0.0	0.1	-0.0
Pavlov. Cond. lever contacts	0.1	0.1	0.3	-0.0	0.0	-0.0	0.2	0.4	-0.1	0.2	0.0	-0.4	0.5
Pavlov. Cond. magazine entry number	1.1	1.3	2.4	-1.0	-1.3	-1.2	-1.5	-1.4	-1.1	-0.8	-1.4	0.6	-0.7
Pavlov. Cond. intertrial magazine entries	1.3	2.0	3.6	-1.3	-1.2	-1.1	-1.1	-1.4	-1.2	-1.5	-1.2	1.8	-1.9
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	0.2	0.4	0.3	0.6	0.5	0.1	0.0	0.3	-0.0	0.1
Pavlov. Cond. response bias	0.4	0.6	1.0	0.6	0.7	0.7	1.0	1.0	0.6	0.7	0.8	-0.7	0.7
Time in closed arm before self-admin	0.2	0.3	0.8	0.9	0.8	0.9	0.1	0.1	0.8	0.4	0.2	-0.3	0.1
Time in closed arm after self-admin	1.5	1.6	2.6	1.6	1.6	1.6	1.4	1.3	1.5	1.0	1.2	-0.5	0.3
Time in open arm before self-admin	0.2	0.2	0.9	0.0	0.1	-0.1	-0.0	0.3	0.0	0.5	0.1	-0.8	0.9
Time in open arm after self-admin	0.4	0.4	1.6	-0.2	-0.3	-0.4	-1.0	-0.7	-0.4	-0.2	-1.3	-0.3	0.5
Bone: periosteal estimation	6.5	13.8	17.7	-4.2	-4.2	-4.2	-3.6	-3.8	-3.8	-3.6	-3.8	2.9	-2.8
Bone: periosteal perimeter	5.8	10.0	12.3	-3.5	-3.4	-3.4	-3.0	-3.2	-3.0	-3.2	-3.1	2.8	-2.7
Bone: post-yield work	3.0	4.4	7.2	-2.7	-2.6	-2.6	-1.5	-1.8	-2.4	-2.1	-1.6	1.7	-1.8
Progressive ratio test 1 active lever presses	2.2	2.7	4.7	-1.7	-1.8	-1.9	-2.2	-1.8	-2.0	-1.3	-1.7	0.8	-0.7
Progressive ratio test 1 breakpoint	2.0	2.4	4.1	-1.6	-1.7	-1.8	-2.0	-1.7	-1.9	-1.2	-1.6	0.7	-0.6
Progressive ratio test 1 inactive lever presses	1.0	1.5	3.7	-1.2	-1.3	-1.3	-1.9	-1.5	-1.4	-1.1	-0.8	0.5	-0.4
Progressive ratio test 2 active lever presses	5.3	6.2	10.4	-2.7	-2.8	-2.6	-3.2	-2.8	-2.7	-2.2	-2.2	1.5	-1.4
Progressive ratio test 2 breakpoint	5.7	6.6	10.9	-2.8	-2.9	-2.7	-3.3	-2.9	-2.8	-2.2	-2.3	1.5	-1.4
Progressive ratio test 2 inactive lever presses	1.0	1.7	5.1	-1.1	-1.3	-1.2	-2.3	-1.7	-1.3	-1.1	-1.2	0.4	-0.2
Incentive Sensitization - Responses	2.9	4.1	7.3	-2.3	-2.2	-2.0	-2.7	-2.5	-2.1	-1.9	-1.4	1.4	-1.1
Incentive Sensitization - Breakpoint	3.5	4.5	7.8	-2.5	-2.3	-2.2	-2.8	-2.6	-2.2	-2.0	-1.4	1.5	-1.2
Sum of active levers in priming session hrs 5-6	1.6	1.5	2.3	1.5	1.3	1.3	0.6	1.0	1.2	1.3	1.1	-1.2	1.3
Progressive ratio	0.2	0.3	1.2	-0.5	-0.1	-0.2	0.2	-0.2	-0.0	-0.7	0.2	1.1	-1.1
Food seeking constrained by brief footshock	2.6	3.2	4.7	-2.2	-2.1	-2.1	-1.1	-1.4	-2.1	-1.8	-0.9	1.8	-1.8
Seeking ratio, punishment vs. effort	0.1	0.1	0.3	-0.3	-0.4	-0.3	-0.0	0.1	-0.5	0.2	-0.1	-0.3	0.2
Retroperitoneal fat weight	0.0	0.2	0.4	-0.6	-0.3	-0.4	-0.4	-0.4	-0.3	-0.4	-0.6	0.3	-0.1
Reaction time number correct	1.0	2.0	4.6	-1.0	-1.0	-1.0	-1.6	-1.6	-1.4	-1.5	-2.1	1.2	-1.2
Reaction time mean minus median	0.1	0.2	0.9	-0.4	-0.7	-0.6	-0.1	0.0	-0.9	0.0	0.3	-0.4	0.5
Reaction time mean minus median AUC	0.1	0.3	1.3	0.2	0.0	-0.0	0.3	0.4	-0.3	0.6	0.5	-0.9	1.2
Reaction time num false alarms	0.9	1.3	3.0	-1.1	-0.8	-0.9	-0.8	-1.1	-0.7	-1.4	-0.8	1.7	-1.6
Reaction time num false alarms AUC	0.5	0.8	2.1	-1.0	-0.7	-0.7	-0.4	-0.8	-0.4	-1.1	-0.4	1.5	-1.4
Reaction time trials correct on left	1.0	2.0	4.6	-1.0	-1.0	-1.0	-1.6	-1.6	-1.4	-1.5	-2.1	1.2	-1.2
Reaction time trials on left	1.0	2.0	4.5	-1.1	-1.0	-1.0	-1.6	-1.6	-1.4	-1.5	-2.1	1.2	-1.2
Reaction time mean	1.8	2.9	4.2	1.5	1.2	1.2	2.0	2.0	1.3	2.0	2.0	-1.8	1.8
Reaction time mean AUC	2.4	3.8	5.4	1.7	1.4	1.5	2.2	2.2	1.5	2.2	2.3	-2.1	2.0
Median of all reaction times	2.9	4.2	5.5	1.9	1.7	1.7	2.3	2.3	1.8	2.3	2.2	-2.1	2.0
Reaction time omissions	0.1	0.1	0.5	0.0	-0.0	0.0	0.7	0.6	0.0	0.4	0.5	-0.3	0.3
Reaction time false alarm rate	0.2	0.2	0.8	-0.5	-0.3	-0.4	0.1	-0.2	0.1	-0.5	0.4	0.9	-0.8
Reaction time premature initiation rate	1.3	1.8	2.3	-1.5	-1.4	-1.5	-1.1	-1.3	-1.2	-1.5	-0.8	1.5	-1.4
Reaction time premature initiations	2.8	5.1	6.0	-2.3	-2.2	-2.3	-2.2	-2.3	-2.2	-2.5	-2.1	2.2	-2.2
Std. dev. reaction times	0.4	0.8	1.8	0.3	0.1	0.1	1.0	1.1	0.0	1.0	1.2	-1.3	1.3
Reaction time trials completed	1.0	2.0	4.5	-1.1	-1.0	-1.0	-1.6	-1.6	-1.4	-1.5	-2.1	1.2	-1.2
Reaction time trials AUC	0.8	1.5	3.6	-0.8	-0.8	-0.7	-1.4	-1.4	-1.2	-1.4	-1.9	1.1	-1.1
Run reversals in cocaine runway, females	0.5	0.5	1.4	0.8	0.6	0.6	-0.1	0.2	0.6	0.7	-0.1	-1.0	1.2
Run reversals in cocaine runway, males	0.1	0.1	0.6	0.0	0.1	0.1	0.6	0.5	-0.1	0.2	0.7	0.0	0.0
Latency to leave start box in cocaine runway	0.7	0.8	1.3	-1.0	-0.8	-0.9	-0.6	-1.0	-0.5	-0.9	-1.1	1.1	-0.9
Latency to leave start box in cocaine runway, F	0.3	0.3	0.8	-0.5	-0.4	-0.3	-0.3	-0.6	-0.1	-0.6	-0.4	0.9	-0.8
Latency to leave start box in cocaine runway, M	0.7	0.6	1.7	-0.8	-0.7	-0.9	-0.7	-0.8	-0.6	-0.7	-1.3	0.6	-0.4
Std. dev. time between licks in bursts	2.5	3.3	4.1	1.7	1.5	1.7	1.9	2.0	1.5	2.0	1.8	-2.0	2.0
Total sessions with >9 infusions	0.1	0.1	0.3	-0.3	-0.3	-0.3	-0.5	-0.2	-0.4	0.1	0.4	-0.4	0.4
Short access day 1 total inactive lever presses	0.4	0.5	2.2	-0.2	-0.5	-0.5	-1.5	-0.9	-0.4	-0.3	-1.0	-0.3	0.3
Short access day 10 total inactive lever presses	0.2	0.4	1.0	0.8	0.9	1.0	0.5	0.6	1.0	0.4	0.5	-0.1	0.1
Short access day 1 total infusions	0.1	0.1	0.2	0.1	-0.0	-0.0	-0.4	0.0	-0.0	0.4	0.4	-0.5	0.5
Short access day 10 total infusions	0.1	0.2	0.6	0.1	0.1	0.0	-0.4	-0.0	-0.0	0.4	0.7	-0.6	0.8
Short access total infusions	0.6	0.8	2.3	-0.9	-0.9	-1.0	-1.5	-1.1	-1.0	-0.6	-0.4	0.3	-0.2
Short access day 1 locomotion	0.2	0.3	0.6	0.5	0.5	0.5	-0.1	0.3	0.5	0.5	0.6	-0.7	0.8
Short access day 10 total locomotion	0.2	0.3	0.6	0.7	0.8	0.7	0.3	0.2	0.7	0.6	0.4	-0.5	0.6
Short access total locomotion	0.8	0.9	2.2	0.9	0.9	0.9	0.4	0.6	0.9	1.1	0.8	-1.3	1.5
One hour access (0.3 mA shock)	7.6	8.8	11.9	-3.3	-3.4	-3.3	-3.5	-3.2	-3.4	-2.8	-2.2	2.0	-2.0
Compulsive drug intake	0.4	0.5	0.8	-0.9	-0.8	-0.7	-0.3	-0.5	-0.7	-0.7	-0.6	0.7	-0.8
One hour access (shock baseline)	2.5	3.9	6.7	-2.1	-2.2	-2.2	-2.6	-2.1	-2.3	-1.9	-1.2	1.3	-1.2
Social response proportion	0.2	0.2	0.7	0.5	0.1	0.2	-0.6	-0.2	-0.2	0.1	-0.8	-0.5	0.5
Social responses	0.5	0.7	1.7	-0.6	-0.8	-0.8	-1.3	-0.9	-1.1	-0.4	-1.0	-0.2	0.3
Social time	0.6	0.9	1.6	0.9	0.9	0.9	1.0	1.0	0.5	1.0	1.3	-0.9	0.8
Soleus weight	1.0	2.9	5.0	-1.7	-2.0	-1.9	-1.8	-1.7	-2.2	-1.4	-2.0	0.6	-0.7
Bone: stiffness	4.1	6.7	9.0	-3.0	-2.8	-2.7	-1.9	-2.4	-2.4	-2.8	-2.0	2.8	-2.7
Tibialis anterior weight	1.1	3.6	8.8	-1.4	-1.0	-0.9	-1.3	-1.9	-1.2	-2.4	-1.5	2.9	-3.0
Time to tail flick, vehicle, before self-admin	1.1	1.1	2.9	1.3	1.1	1.0	0.2	0.6	0.9	1.1	0.2	-1.4	1.7
Time to tail flick, vehicle, after self-admin	0.8	1.0	4.1	-0.6	-0.1	-0.1	-0.2	-0.6	-0.0	-1.1	0.4	1.9	-2.0
Time to tail flick, test, before self-admin	1.2	1.3	1.7	-1.1	-1.0	-1.2	-1.1	-1.2	-1.1	-1.3	-1.3	1.0	-1.0
Time to tail flick, test, after self-admin	1.7	1.8	3.2	1.6	1.8	1.7	1.1	1.1	1.8	1.2	0.7	-0.8	0.9
Delta time to tail flick, vehicle, before/after SA	4.6	4.4	13.2	-2.0	-1.4	-1.3	-1.0	-1.7	-1.2	-2.4	-0.7	3.4	-3.6
Delta time to tail flick, test, before/after SA	1.1	1.1	2.0	1.2	1.2	1.4	0.9	1.0	1.4	1.0	0.9	-0.7	0.7
Tibia length	0.1	0.3	0.8	-0.9	-0.9	-0.8	-0.1	-0.4	-0.3	-0.3	-0.5	0.4	-0.4
Ambulatory time before self-admin	0.6	0.9	1.5	1.1	1.2	1.2	1.0	1.0	1.2	0.9	0.6	-0.6	0.7
Ambulatory time after self-admin	0.3	0.4	1.6	0.2	-0.1	-0.2	-1.1	-0.8	-0.2	-0.3	-1.3	-0.3	0.2
Bone: tissue strength	0.3	0.3	1.1	0.3	0.1	0.1	0.5	0.6	0.1	0.7	0.6	-1.1	0.9
Total heroin consumption	1.0	1.2	1.7	-1.0	-1.0	-1.1	-1.3	-1.2	-1.0	-1.1	-0.5	1.2	-1.2
Bone: trabecular number	4.2	7.0	10.7	-2.6	-2.9	-3.0	-3.3	-2.9	-2.9	-2.3	-3.2	1.2	-1.1
Bone: trabecular spacing	1.5	2.0	4.1	1.2	1.6	1.6	2.0	1.7	1.3	1.1	1.9	-0.4	0.4
Bone: trabecular thickness	4.5	5.6	7.3	-2.5	-2.6	-2.7	-2.7	-2.6	-2.4	-2.2	-2.7	1.4	-1.4
Bone: trabecular tissue density	1.4	2.0	3.3	-1.2	-1.3	-1.2	-1.8	-1.7	-1.1	-1.4	-1.7	1.3	-1.3
Water consumed over 24 hours	0.2	0.3	1.1	0.2	0.6	0.4	0.1	-0.2	0.4	-0.4	-0.1	1.1	-0.9
Number of responses in last shaping day	0.4	0.5	1.9	-0.3	-0.7	-0.6	-0.4	0.1	-0.5	0.7	0.2	-1.4	1.1