Hub : Genes

Btaf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC mRNA stability Btaf1 0.11 0.08 1.9e-03 0.05 0.05 0.05 0.04 4.2e-03 3.9e-03 4.1e-03 5.8e-03
2 Brain alternative TSS XM_039085850.2 0.04 0.03 6.2e-03 0.02 0.01 0.01 0.01 6.5e-03 6.2e-02 4.0e-02 6.0e-02
3 PL alternative TSS XM_039085850.2 0.03 0.02 7.4e-04 0.03 0.02 0.02 0.02 6.1e-04 2.0e-03 4.4e-03 2.4e-03
4 NAcc mRNA stability Btaf1 0.01 0.01 9.4e-03 0.01 0.01 0 0 1.0e-02 3.4e-02 2.1e-01 5.1e-02
5 PL gene expression Btaf1 0.02 0.01 9.1e-03 0 0.01 0.01 0 8.8e-02 6.9e-02 6.5e-02 2.3e-01
6 NAcc gene expression Btaf1 0.02 0.01 7.7e-04 0.03 0.02 0.01 0.02 4.9e-05 8.1e-04 2.4e-02 3.4e-04
7 Brain mRNA stability Btaf1 0.13 0.08 2.1e-10 0.1 0.11 0.1 0.12 5.5e-10 4.4e-10 4.9e-10 4.2e-11
8 IC gene expression Btaf1 0.12 0.07 5.2e-05 0.12 0.12 0.11 0.12 7.3e-06 1.3e-05 2.8e-05 8.7e-06
9 Adipose gene expression Btaf1 0.06 0.04 2.1e-05 0.04 0.04 0.02 0.03 7.7e-05 8.8e-05 1.3e-03 2.3e-04
10 Brain gene expression Btaf1 0.03 0.02 4.4e-03 0.02 0.01 0.01 0.01 7.2e-03 5.1e-02 2.6e-02 3.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density6.612.218.2-3.43.73.74.33.93.6-3.34.3-2.11.9
Area under the delay curve0.20.30.50.6-0.7-0.7-0.6-0.6-0.70.3-0.30.0-0.0
BMI with tail0.10.40.9-0.60.60.70.90.70.9-0.60.5-0.00.0
BMI without tail0.00.10.2-0.50.20.2-0.0-0.00.1-0.3-0.2-0.20.2
Body weight1.46.010.2-3.22.62.82.02.32.5-2.71.4-2.42.3
Weight adjusted by age0.10.20.60.6-0.4-0.50.50.3-0.40.00.80.5-0.3
Bone surface3.46.79.4-2.93.03.13.02.82.5-2.23.1-1.31.1
Bone volume5.210.413.9-3.53.53.63.63.53.2-3.13.7-2.12.0
Breakpoint value in progressive ratio session0.30.51.3-0.40.30.40.60.70.4-0.90.1-1.11.1
Number of licking bursts0.92.74.71.9-2.2-2.0-1.7-1.6-1.61.3-1.61.0-1.3
Context. condit. distance diff. score3.03.75.7-1.91.81.81.61.91.8-2.11.6-2.12.4
Locomotion velocity, session 14.04.57.72.1-2.1-2.0-1.6-2.1-1.62.1-1.72.7-2.8
Locomotion distance, session 10.30.40.80.7-0.8-0.7-0.3-0.5-0.60.6-0.60.7-0.9
Locomotion velocity, session 21.01.21.71.0-1.1-1.0-0.9-1.1-0.91.2-1.11.2-1.3
Locomotion distance, session 20.20.30.80.4-0.7-0.5-0.6-0.6-0.80.4-0.90.0-0.2
Locomotion velocity, session 30.20.30.5-0.70.60.50.20.30.7-0.50.3-0.60.7
Locomotion distance, session 31.11.32.9-1.31.11.10.30.81.1-1.20.4-1.61.7
Stereotopy head waving bouts, day 30.20.31.00.4-0.1-0.3-0.1-0.4-0.20.6-0.11.0-0.9
Stereotopy head waving duration, day 30.20.30.90.5-0.3-0.40.1-0.3-0.20.50.10.9-0.9
Locomotion velocity, session 71.21.32.7-0.90.60.60.91.10.7-1.40.9-1.61.6
Locomotion distance, session 71.11.52.7-1.00.80.91.01.20.9-1.51.1-1.61.6
Stereotopy head waving bouts, day 70.30.30.60.2-0.1-0.2-0.7-0.7-0.40.7-0.60.8-0.6
Stereotopy head waving duration, day 70.20.20.8-0.10.20.2-0.4-0.5-0.10.6-0.40.9-0.7
Locomotion velocity, session 80.30.30.5-0.60.50.60.70.70.7-0.60.5-0.50.5
Locomotion distance, session 80.71.02.5-0.90.50.70.81.00.5-1.20.7-1.51.6
Degree of sensitization distance0.10.20.50.6-0.7-0.60.20.1-0.5-0.20.2-0.1-0.0
Degree of sensitization stereotypy0.10.10.2-0.30.40.4-0.3-0.20.10.4-0.30.4-0.2
Conditioned locomotion0.70.81.3-0.80.70.71.01.00.9-1.01.1-0.90.8
Cocaine response after cond. corrected0.00.00.10.10.10.10.0-0.0-0.10.10.10.2-0.2
Cocaine response after cond. not corrected0.10.10.3-0.40.40.50.10.20.2-0.40.2-0.50.5
Cocaine response before conditioning0.10.20.5-0.2-0.00.1-0.6-0.1-0.2-0.2-0.7-0.70.7
Saline control response0.20.30.90.1-0.2-0.30.20.5-0.1-0.60.4-0.90.8
Bone: connectivity density3.14.99.2-2.02.42.43.02.62.2-1.92.8-0.80.8
Bone: cortical apparent density1.52.33.51.7-1.6-1.6-1.2-1.5-1.91.5-1.21.5-1.5
Bone: cortical area4.47.210.3-3.22.92.92.12.52.5-3.02.1-2.72.6
Bone: cortical porosity0.00.00.10.3-0.4-0.4-0.1-0.1-0.20.2-0.1-0.0-0.1
Bone: cortical porosity0.00.00.1-0.20.10.10.10.20.1-0.10.1-0.30.3
Bone: cortical thickness0.81.32.5-1.51.11.10.40.90.7-1.50.4-1.61.4
Bone: cortical thickness0.10.20.40.3-0.6-0.6-0.5-0.4-0.70.1-0.3-0.20.0
Bone: cortical tissue density1.62.53.71.8-1.7-1.7-1.2-1.5-1.91.6-1.21.6-1.6
Condit. Reinf. active minus inactive responses0.60.71.50.7-0.9-0.9-1.2-1.0-0.80.7-1.10.3-0.3
Condit. Reinf. active-inactive response ratio1.41.52.01.1-1.0-1.1-1.4-1.4-1.01.3-1.31.3-1.2
Condit. Reinf. active responses0.20.20.8-0.40.10.1-0.20.00.3-0.5-0.1-0.80.9
Condit. Reinf. inactive responses1.41.83.0-1.41.11.11.11.31.2-1.51.2-1.71.7
Incentive salience index mean0.60.81.90.6-1.0-1.0-1.4-1.1-0.80.4-1.3-0.10.1
Condit. Reinf. lever presses0.81.32.31.0-1.3-1.4-1.5-1.3-1.10.6-1.50.2-0.2
Condit. Reinf. active minus inactive responses0.50.72.1-0.80.60.50.40.70.4-1.00.4-1.41.4
Condit. Reinf. active-inactive response ratio0.00.10.3-0.1-0.1-0.2-0.00.1-0.2-0.20.2-0.50.5
Condit. Reinf. active responses1.72.43.4-1.81.61.51.11.41.3-1.61.3-1.81.8
Condit. Reinf. inactive responses1.32.03.0-1.71.71.71.01.21.6-1.41.0-1.21.3
Condit. Reinf. lever presses0.10.10.3-0.30.20.20.10.20.4-0.20.5-0.20.1
Condit. Reinf. lever reinforcers received1.01.42.3-1.31.21.10.81.11.0-1.31.0-1.51.5
Conditioned reinforcement - actives0.41.52.4-1.51.41.31.51.31.4-1.20.7-0.80.6
Conditioned reinforcement - inactives0.41.12.1-1.11.11.11.41.21.1-1.00.9-0.60.5
Conditioned locomotion0.71.01.9-1.11.31.21.41.01.3-0.70.6-0.2-0.0
Patch foraging indifference point 0 sec0.10.20.7-0.30.10.1-0.5-0.30.10.5-0.90.6-0.7
Patch foraging indifference point AUC0.40.92.10.8-0.9-0.9-1.2-1.2-0.90.8-1.40.4-0.5
Delay disc. indifference point, 0s delay0.60.72.3-0.1-0.1-0.20.30.6-0.3-1.10.6-1.51.5
Delay disc. indifference point, 16s delay0.10.10.3-0.30.30.30.30.20.4-0.10.6-0.00.0
Delay disc. indifference point, 2s delay0.30.30.60.8-0.7-0.7-0.0-0.3-0.80.50.20.4-0.4
Delay disc. indifference point, 24s delay0.60.92.50.7-0.9-1.0-1.6-1.3-0.80.5-1.20.1-0.0
Delay disc. indifference point, 4s delay0.10.10.50.1-0.3-0.3-0.1-0.0-0.3-0.30.0-0.70.7
Delay disc. indifference point, 8s delay1.42.43.21.7-1.8-1.7-1.6-1.6-1.71.4-1.31.2-1.2
Indifference point function ln k0.51.72.5-1.51.41.31.21.41.3-1.11.6-0.91.0
Indifference point function log k0.51.72.5-1.51.41.31.21.41.3-1.11.6-0.91.0
Patch foraging total patch changes 0 sec0.10.20.6-0.30.20.3-0.4-0.20.20.4-0.80.5-0.6
Patch foraging total patch changes 12 sec1.41.92.81.4-1.3-1.3-1.4-1.5-1.21.5-1.71.3-1.3
Patch foraging total patch changes 18 sec0.10.30.60.5-0.6-0.6-0.5-0.7-0.50.6-0.80.5-0.6
Patch foraging total patch changes 24 sec0.10.20.6-0.1-0.2-0.2-0.7-0.5-0.50.4-0.80.0-0.1
Patch foraging total patch changes 6 sec1.01.63.40.8-0.9-0.8-1.6-1.4-0.91.4-1.81.3-1.4
Patch foraging time to switch 0 sec0.31.32.21.5-1.4-1.3-0.9-1.2-1.21.1-0.71.0-0.9
Patch foraging water rate 0 sec0.10.50.9-1.00.90.80.60.80.8-0.70.4-0.70.6
Patch foraging water rate 12 sec0.20.71.5-1.21.11.00.80.81.1-0.80.4-0.50.5
Patch foraging water rate 18 sec0.61.32.0-1.41.21.30.91.21.1-1.10.6-1.11.1
Patch foraging water rate 24 sec1.82.63.7-1.81.51.61.11.71.7-1.81.0-1.91.9
Patch foraging water rate 6 sec0.10.10.2-0.40.40.30.20.30.30.10.30.3-0.3
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.1-0.1-0.0-0.3-0.0-0.1-0.3-0.2-0.40.3
Distance traveled before self-admin0.10.30.50.6-0.7-0.7-0.6-0.5-0.70.4-0.20.2-0.2
Distance traveled after self-admin0.20.41.30.6-0.2-0.10.80.4-0.10.21.10.8-0.7
Extensor digitorum longus weight0.83.17.9-1.71.41.10.91.51.2-2.21.1-2.62.8
Bone: elastic displacement3.54.46.82.4-2.0-2.2-1.3-1.8-1.92.6-1.22.5-2.4
Bone: elastic work2.02.64.51.9-1.6-1.7-0.6-1.1-1.62.0-0.52.1-2.0
Bone: endosteal estimation4.210.213.4-3.53.73.63.33.33.4-2.83.6-2.12.2
Bone: endosteal perimeter4.410.713.4-3.53.73.63.63.53.4-3.03.6-2.22.2
Epididymis fat weight0.73.54.6-1.71.71.92.12.02.1-1.92.0-1.51.3
Delta time in closed arm before/after self-admin0.70.62.00.5-0.6-0.5-1.0-1.1-0.60.5-1.40.5-0.4
Delta time in open arm before/after self-admin0.20.20.70.7-0.6-0.60.10.0-0.60.20.90.2-0.2
Diff in mean of infusions in LGA sessions0.30.60.9-0.80.70.70.90.90.7-0.80.5-0.90.8
Delay discount exponential model param0.20.30.5-0.60.70.70.70.70.6-0.30.4-0.10.0
Extinction: sum of active levers before priming0.30.51.2-0.80.60.70.10.30.9-0.9-0.2-1.01.1
Active lever presses in extinction session 61.31.32.9-0.50.40.41.31.30.5-1.31.1-1.71.6
Bone: final force1.72.74.4-2.12.01.91.31.61.4-1.71.4-1.51.4
Bone: final moment1.42.33.8-1.91.91.81.31.51.4-1.41.4-1.11.0
Food consumed during 24 hour testing period0.10.10.4-0.2-0.00.1-0.6-0.30.20.2-0.60.1-0.1
Glucose0.00.10.2-0.40.50.4-0.1-0.00.2-0.2-0.0-0.20.2
Heart weight0.40.62.2-0.40.50.6-0.3-0.40.50.6-0.31.3-1.5
Delay discount hyperbolic model param0.30.40.7-0.70.80.80.60.70.8-0.50.4-0.20.2
Intermittent access intake day 1-15 change0.42.23.9-1.92.01.81.81.51.9-1.20.6-0.70.6
Intermittent access intake escalation0.52.53.9-1.92.01.81.81.61.9-1.30.8-0.90.9
Intermittent access intake escalation 20.40.71.2-1.11.00.91.10.90.9-0.80.2-0.60.5
Intermitt. access day 1 inactive lever presses0.10.91.21.1-1.1-1.1-0.8-0.7-1.11.1-0.11.0-1.0
Intermitt. access day 15 inactive lever presses0.31.42.8-1.11.41.41.71.21.3-0.81.4-0.10.1
Intermitt. access escalation Index0.10.41.10.7-0.8-0.7-0.8-0.8-0.60.2-1.10.0-0.1
Intermittent access day 1 total infusions0.61.73.3-1.31.21.31.81.61.4-1.21.1-1.00.8
Intermittent access day 15 total infusions2.56.08.4-2.92.92.82.92.62.8-2.31.4-1.81.7
Intermittent access terminal intake (last 3 days)2.23.86.2-2.32.22.22.52.12.3-1.81.1-1.21.1
Intermittent access total infusions2.93.55.7-2.12.02.02.42.12.1-1.81.2-1.41.3
Intermittent access day 1 locomotion0.91.62.5-1.51.31.31.51.61.3-1.11.1-0.90.8
Intermittent access day 15 total locomotion0.83.05.8-1.92.01.92.41.92.0-1.31.5-0.80.6
Intermittent access total locomotion2.32.75.7-1.71.71.62.42.01.7-1.51.6-1.00.9
Intermittent access standard deviation0.42.23.4-1.81.81.81.61.31.8-1.40.7-1.10.9
Left kidney weight0.43.36.4-2.52.32.31.01.51.8-1.90.6-1.71.7
Right kidney weight0.21.53.6-1.91.61.60.20.71.1-1.3-0.3-1.21.2
Cocaine induced anxiety0.10.30.6-0.10.10.10.70.70.1-0.80.6-0.80.8
Post-drug Anxiety0.30.40.9-0.40.60.70.90.60.6-0.50.9-0.20.2
Baseline Anxiety0.20.40.8-0.60.90.90.50.30.9-0.00.70.4-0.4
Tail length0.52.55.0-2.11.61.50.61.10.9-1.80.8-2.22.2
Length with tail1.87.812.7-3.63.03.02.02.52.5-3.01.7-3.13.0
Length without tail2.010.813.4-3.73.43.52.93.43.4-3.52.6-3.13.1
Times rat made contact with spout0.10.20.50.2-0.5-0.40.20.2-0.1-0.40.3-0.70.5
Lifetime Intake2.63.36.0-1.91.91.92.42.12.0-1.71.2-1.31.2
Liver weight, left0.91.62.8-1.71.51.50.71.01.2-1.31.1-1.21.2
Liver weight, right1.62.83.9-1.91.91.81.81.82.0-1.61.4-1.11.4
Locomotor activity0.50.91.31.0-0.9-0.9-0.8-0.8-1.11.0-0.61.0-1.0
Locomotor testing distance0.71.82.31.3-1.3-1.2-1.1-1.2-1.31.5-1.31.5-1.5
Locomotor testing rearing0.00.10.3-0.20.10.10.20.40.2-0.40.2-0.60.6
Locomotion in novel chamber1.01.43.1-0.91.01.01.41.40.9-0.91.7-1.01.1
Locomotion in novel chamber post-restriction1.33.85.6-2.01.81.71.42.01.7-2.11.7-2.42.3
Fecal boli incidents, locomotor time 10.10.20.7-0.1-0.00.10.40.4-0.0-0.70.1-0.80.8
Change in fecal boli incidents, locomotor task0.20.30.70.2-0.2-0.3-0.8-0.5-0.40.6-0.80.5-0.4
Time >=10cm from walls, locomotor time 13.74.67.7-2.42.12.11.11.81.8-2.51.5-2.82.7
Bouts of movement, locomotor time 10.30.40.8-0.50.40.40.90.80.3-0.70.2-0.80.5
Total resting periods, locomotor time 10.50.51.1-0.70.50.51.00.90.3-0.90.3-1.00.7
Rest time, locomotor task time 10.20.40.70.8-0.7-0.70.2-0.2-0.80.4-0.40.7-0.7
Distance moved, locomotor task time 10.10.31.0-0.40.20.1-1.0-0.3-0.10.0-0.3-0.70.8
Vertical activity count, locomotor time 10.00.20.6-0.70.70.6-0.20.20.8-0.30.1-0.40.4
Time >=10cm from walls, locomotor time 20.10.41.7-0.50.10.1-0.20.3-0.0-0.80.0-1.31.3
Bouts of movement, locomotor time 20.62.13.81.7-1.9-1.9-0.9-1.1-1.71.1-1.60.9-1.1
Total resting periods, locomotor time 20.52.03.71.6-1.9-1.8-0.9-1.1-1.71.0-1.70.7-1.0
Rest time, locomotor task time 20.10.10.30.1-0.2-0.20.30.1-0.2-0.4-0.2-0.50.5
Distance moved, locomotor task time 20.10.20.7-0.50.40.3-0.6-0.10.1-0.10.0-0.60.8
Vertical activity count, locomotor time 20.20.40.80.5-0.5-0.4-0.9-0.8-0.40.8-0.80.7-0.6
Light reinforcement 10.10.20.9-0.00.20.10.90.6-0.0-0.10.90.4-0.4
Light reinforcement 22.14.77.12.7-2.4-2.4-1.1-1.8-2.12.2-1.22.6-2.5
Bone: marrow area4.410.814.1-3.63.83.73.53.43.5-2.83.7-2.22.2
Bone: maximum diameter9.018.021.4-4.64.64.64.34.44.4-4.24.5-3.33.3
Bone: maximum force2.54.97.2-2.72.72.62.12.32.1-2.12.2-1.71.6
Bone: maximum moment2.24.26.6-2.52.62.52.02.12.1-1.82.1-1.21.2
Mean time between licks in bursts0.42.33.91.3-1.2-1.2-1.5-1.7-1.01.6-1.61.9-2.0
Mean num. licks in bursts0.92.42.8-1.61.61.61.61.61.4-1.41.7-1.31.4
Cd content in liver1.82.13.41.0-1.0-1.0-1.6-1.6-0.81.5-1.71.8-1.9
Co content in liver1.41.63.81.1-0.8-0.8-0.8-1.2-1.11.5-1.01.8-2.0
Cu content in liver2.83.36.32.0-1.6-1.6-1.0-1.5-1.72.2-0.92.5-2.5
Fe content in liver1.41.73.41.1-1.1-1.1-1.5-1.4-1.81.4-1.31.1-1.1
K content in liver0.60.61.51.1-1.2-1.1-0.4-0.4-1.20.3-0.4-0.20.1
Mg content in liver0.70.71.21.1-1.1-1.1-0.7-0.7-1.10.8-0.50.6-0.6
Mn content in liver1.31.41.91.4-1.3-1.2-1.0-1.2-1.21.2-1.01.1-1.2
Na content in liver1.11.32.71.3-1.5-1.3-1.2-1.1-1.70.8-1.20.1-0.3
Rb content in liver0.20.20.5-0.50.60.50.30.50.3-0.30.7-0.40.6
Se content in liver25.930.734.35.6-5.5-5.4-5.6-5.9-5.75.7-5.85.1-5.2
Sr content in liver1.00.82.90.9-0.6-0.5-0.1-0.6-0.41.1-0.21.6-1.7
Zn content in liver7.28.412.53.1-3.2-3.3-2.9-2.9-3.52.6-3.11.9-2.0
Bone: minimum diameter7.614.720.4-4.54.54.43.23.74.1-3.73.3-3.23.3
Time in familiar zone, hab. session 10.10.10.2-0.10.20.20.30.20.10.10.40.3-0.5
Time in novel zone, hab. session 10.50.50.80.8-0.8-0.8-0.7-0.7-0.90.7-0.90.3-0.2
Total zone transitions, hab. session 10.00.00.2-0.10.10.10.40.20.2-0.00.40.0-0.0
Total locomotion distance, hab. session 10.50.71.41.0-1.2-1.1-0.6-0.7-1.10.8-0.50.4-0.5
Locomotion velocity, hab. session 10.71.01.91.2-1.4-1.4-0.8-0.9-1.30.9-0.60.4-0.5
Time in familiar zone, hab. session 20.50.51.20.7-0.6-0.6-0.6-0.7-0.50.8-0.51.0-1.1
Time in novel zone, hab. session 20.00.00.1-0.20.20.20.30.20.2-0.20.1-0.20.2
Total zone transitions, hab. session 20.40.50.80.4-0.5-0.5-0.8-0.8-0.60.8-0.80.9-0.9
Total locomotion distance, hab. session 20.60.81.20.8-0.9-0.8-0.9-0.9-1.10.9-1.00.8-0.8
Locomotion velocity, hab. session 20.50.71.40.8-1.0-0.9-0.8-0.9-1.20.8-0.90.5-0.5
Novel to familiar place preference ratio0.60.81.9-0.40.60.51.41.10.5-0.81.0-0.81.0
Novelty place preference0.70.82.1-0.50.70.61.51.20.5-0.81.2-0.81.0
Time in novel zone, NPP test0.50.61.5-0.30.50.41.20.90.4-0.61.0-0.60.9
Total zone transitions, NPP test0.40.60.90.6-0.9-0.8-1.0-0.9-0.70.6-0.90.4-0.4
Total locomotion distance, NPP test1.31.83.01.5-1.7-1.6-1.3-1.4-1.61.3-1.20.7-0.9
Locomotion velocity, NPP test1.11.52.71.3-1.7-1.5-1.2-1.3-1.51.1-1.10.5-0.6
Intraocular pressure0.20.30.9-0.60.50.60.70.70.5-0.20.9-0.3-0.0
Delta distance traveled before/after self-admin1.71.93.9-1.01.41.52.01.61.5-1.21.7-0.40.5
Delta ambulatory time before/after self-admin1.32.34.2-1.21.51.72.11.81.7-1.41.9-0.50.7
Parametrial fat weight0.20.62.1-0.0-0.6-0.5-1.2-0.7-0.80.1-1.5-0.50.4
Pavlov. Cond. lever latency0.30.41.2-0.20.50.60.60.20.40.40.71.1-0.8
Pavlov. Cond. magazine entry latency0.60.82.50.4-0.7-0.7-1.5-1.1-0.80.3-1.60.1-0.2
Pavlov. Cond. change in total contacts1.21.33.30.7-0.9-0.9-1.8-1.4-0.90.8-1.80.5-0.7
Pavlov. Cond. index score0.40.51.40.1-0.5-0.6-1.1-0.6-0.5-0.3-1.2-0.80.6
Pavlov. Cond. latency score0.40.51.30.0-0.5-0.5-1.0-0.4-0.4-0.5-1.0-1.10.9
Pavlov. Cond. lever contacts0.40.51.30.4-0.7-0.8-1.0-0.6-0.6-0.0-1.1-0.70.5
Pavlov. Cond. magazine entry number0.30.41.5-0.10.40.41.10.80.4-0.11.2-0.10.2
Pavlov. Cond. intertrial magazine entries0.50.60.9-0.80.60.70.70.80.7-0.80.9-1.00.9
Pavlov. Cond. lever-magazine prob. diff.0.60.72.10.4-0.8-0.8-1.4-0.9-0.80.0-1.5-0.50.4
Pavlov. Cond. response bias0.91.12.60.7-0.9-0.9-1.6-1.3-0.90.7-1.60.5-0.7
Pavlov. Cond. lever latency0.10.10.4-0.10.10.10.20.40.0-0.30.0-0.60.6
Pavlov. Cond. magazine entry latency0.81.11.70.9-1.2-1.0-1.3-1.3-0.90.8-1.30.7-0.8
Pavlov. Cond. change in total contacts0.00.10.30.2-0.3-0.3-0.5-0.4-0.20.0-0.2-0.20.2
Pavlov. Cond. index score0.00.00.20.0-0.2-0.1-0.4-0.40.1-0.1-0.2-0.0-0.0
Pavlov. Cond. latency score0.00.00.1-0.1-0.10.0-0.2-0.20.1-0.1-0.0-0.10.0
Pavlov. Cond. lever contacts0.00.10.3-0.0-0.00.0-0.2-0.40.10.2-0.00.4-0.5
Pavlov. Cond. magazine entry number1.01.32.4-1.01.31.21.51.41.1-0.81.4-0.60.7
Pavlov. Cond. intertrial magazine entries0.92.03.6-1.31.21.11.11.41.2-1.51.2-1.81.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.2-0.4-0.3-0.6-0.5-0.10.0-0.30.0-0.1
Pavlov. Cond. response bias0.40.61.00.6-0.7-0.7-1.0-1.0-0.60.7-0.80.7-0.7
Time in closed arm before self-admin0.20.30.80.9-0.8-0.9-0.1-0.1-0.80.4-0.20.3-0.1
Time in closed arm after self-admin1.41.62.61.6-1.6-1.6-1.4-1.3-1.51.0-1.20.5-0.3
Time in open arm before self-admin0.10.20.90.0-0.10.10.0-0.3-0.00.5-0.10.8-0.9
Time in open arm after self-admin0.40.41.6-0.20.30.41.00.70.4-0.21.30.3-0.5
Bone: periosteal estimation5.813.817.7-4.24.24.23.63.83.8-3.63.8-2.92.8
Bone: periosteal perimeter5.110.012.3-3.53.43.43.03.23.0-3.23.1-2.82.7
Bone: post-yield work2.64.47.2-2.72.62.61.51.82.4-2.11.6-1.71.8
Progressive ratio test 1 active lever presses1.62.74.7-1.71.81.92.21.82.0-1.31.7-0.80.7
Progressive ratio test 1 breakpoint1.42.44.1-1.61.71.82.01.71.9-1.21.6-0.70.6
Progressive ratio test 1 inactive lever presses0.61.53.7-1.21.31.31.91.51.4-1.10.8-0.50.4
Progressive ratio test 2 active lever presses4.46.210.4-2.72.82.63.22.82.7-2.22.2-1.51.4
Progressive ratio test 2 breakpoint5.16.610.9-2.82.92.73.32.92.8-2.32.3-1.51.4
Progressive ratio test 2 inactive lever presses0.51.75.1-1.11.31.22.31.71.3-1.11.2-0.40.2
Incentive Sensitization - Responses1.54.17.3-2.32.22.02.72.52.1-1.91.4-1.41.1
Incentive Sensitization - Breakpoint2.04.57.8-2.52.32.22.82.62.2-2.01.4-1.51.2
Sum of active levers in priming session hrs 5-61.61.52.31.5-1.3-1.3-0.6-1.0-1.21.3-1.11.2-1.3
Progressive ratio0.10.31.2-0.50.10.2-0.20.20.0-0.7-0.2-1.11.1
Food seeking constrained by brief footshock2.53.24.7-2.22.12.11.11.42.1-1.80.9-1.81.8
Seeking ratio, punishment vs. effort0.00.10.3-0.30.40.30.0-0.10.50.20.10.3-0.2
Retroperitoneal fat weight0.00.20.4-0.60.30.40.40.40.3-0.40.6-0.30.1
Reaction time number correct0.62.04.6-1.01.01.01.61.61.4-1.52.1-1.21.2
Reaction time mean minus median0.00.20.9-0.40.70.60.1-0.00.90.0-0.30.4-0.5
Reaction time mean minus median AUC0.00.31.30.2-0.00.0-0.3-0.40.30.6-0.50.9-1.2
Reaction time num false alarms0.81.33.0-1.10.80.90.81.10.7-1.40.8-1.71.6
Reaction time num false alarms AUC0.40.82.1-1.00.70.70.40.80.4-1.10.4-1.51.4
Reaction time trials correct on left0.62.04.6-1.01.01.01.61.61.4-1.52.1-1.21.2
Reaction time trials on left0.62.04.5-1.11.01.01.61.61.4-1.52.1-1.21.2
Reaction time mean1.32.94.21.5-1.2-1.2-2.0-2.0-1.32.0-2.01.8-1.8
Reaction time mean AUC1.63.85.41.7-1.4-1.5-2.2-2.2-1.52.2-2.32.1-2.0
Median of all reaction times2.74.25.51.9-1.7-1.7-2.3-2.3-1.82.3-2.22.1-2.0
Reaction time omissions0.10.10.50.00.0-0.0-0.7-0.6-0.00.4-0.50.3-0.3
Reaction time false alarm rate0.20.20.8-0.50.30.4-0.10.2-0.1-0.5-0.4-0.90.8
Reaction time premature initiation rate1.11.82.3-1.51.41.51.11.31.2-1.50.8-1.51.4
Reaction time premature initiations1.75.16.0-2.32.22.32.22.32.2-2.52.1-2.22.2
Std. dev. reaction times0.20.81.80.3-0.1-0.1-1.0-1.1-0.01.0-1.21.3-1.3
Reaction time trials completed0.62.04.5-1.11.01.01.61.61.4-1.52.1-1.21.2
Reaction time trials AUC0.41.53.6-0.80.80.71.41.41.2-1.41.9-1.11.1
Run reversals in cocaine runway, females0.40.51.40.8-0.6-0.60.1-0.2-0.60.70.11.0-1.2
Run reversals in cocaine runway, males0.10.10.60.0-0.1-0.1-0.6-0.50.10.2-0.7-0.0-0.0
Latency to leave start box in cocaine runway0.60.81.3-1.00.80.90.61.00.5-0.91.1-1.10.9
Latency to leave start box in cocaine runway, F0.20.30.8-0.50.40.30.30.60.1-0.60.4-0.90.8
Latency to leave start box in cocaine runway, M0.70.61.7-0.80.70.90.70.80.6-0.81.3-0.60.4
Std. dev. time between licks in bursts1.83.34.11.7-1.5-1.7-1.9-2.0-1.52.0-1.82.0-2.0
Total sessions with >9 infusions0.10.10.3-0.30.30.30.50.20.40.1-0.40.4-0.4
Short access day 1 total inactive lever presses0.20.52.2-0.20.50.51.50.90.4-0.31.00.3-0.3
Short access day 10 total inactive lever presses0.10.41.00.8-0.9-1.0-0.5-0.6-1.00.4-0.50.1-0.1
Short access day 1 total infusions0.00.10.20.10.00.00.4-0.00.00.4-0.40.5-0.5
Short access day 10 total infusions0.10.20.60.1-0.1-0.00.40.00.00.4-0.70.6-0.8
Short access total infusions0.50.82.3-0.90.91.01.51.11.0-0.60.4-0.30.2
Short access day 1 locomotion0.20.30.60.5-0.5-0.50.1-0.3-0.50.5-0.60.7-0.8
Short access day 10 total locomotion0.10.30.60.7-0.8-0.7-0.3-0.2-0.70.6-0.40.5-0.6
Short access total locomotion0.60.92.20.9-0.9-0.9-0.4-0.6-0.91.1-0.81.3-1.5
One hour access (0.3 mA shock)7.48.811.9-3.33.43.33.53.23.4-2.82.2-2.02.0
Compulsive drug intake0.30.50.8-0.90.80.70.30.50.7-0.70.6-0.70.8
One hour access (shock baseline)1.53.96.7-2.12.22.22.62.12.3-1.91.2-1.31.2
Social response proportion0.20.20.70.5-0.1-0.20.60.20.20.10.80.5-0.5
Social responses0.50.71.7-0.60.80.81.30.91.1-0.41.00.2-0.3
Social time0.60.91.60.9-0.9-0.9-1.0-1.0-0.51.0-1.30.9-0.8
Soleus weight1.02.95.0-1.72.01.91.81.72.2-1.52.0-0.60.7
Bone: stiffness3.76.79.0-3.02.82.71.92.42.4-2.82.0-2.82.7
Tibialis anterior weight1.03.68.8-1.41.00.91.31.91.2-2.41.5-2.93.0
Time to tail flick, vehicle, before self-admin0.91.12.91.3-1.1-1.0-0.2-0.6-0.91.1-0.21.4-1.7
Time to tail flick, vehicle, after self-admin0.51.04.1-0.60.10.10.20.60.0-1.1-0.4-1.92.0
Time to tail flick, test, before self-admin1.11.31.7-1.11.01.21.11.21.1-1.31.3-1.01.0
Time to tail flick, test, after self-admin1.71.83.21.6-1.8-1.7-1.1-1.1-1.81.2-0.70.8-0.9
Delta time to tail flick, vehicle, before/after SA4.14.413.2-2.01.41.31.01.71.2-2.40.7-3.43.6
Delta time to tail flick, test, before/after SA0.91.12.01.2-1.2-1.4-0.9-1.0-1.41.0-0.90.7-0.7
Tibia length0.10.30.8-0.90.90.80.10.40.3-0.30.5-0.40.4
Ambulatory time before self-admin0.30.91.51.1-1.2-1.2-1.0-1.0-1.20.9-0.60.6-0.7
Ambulatory time after self-admin0.20.41.60.20.10.21.10.80.2-0.31.30.3-0.2
Bone: tissue strength0.30.31.10.3-0.1-0.1-0.5-0.6-0.10.7-0.61.1-0.9
Total heroin consumption1.01.21.7-1.01.01.11.31.21.0-1.10.5-1.21.2
Bone: trabecular number3.77.010.7-2.62.93.03.32.92.9-2.33.2-1.21.1
Bone: trabecular spacing1.42.04.11.2-1.6-1.6-2.0-1.7-1.31.1-1.90.4-0.4
Bone: trabecular thickness4.05.67.3-2.52.62.72.72.62.4-2.22.7-1.41.4
Bone: trabecular tissue density1.12.03.3-1.21.31.21.81.71.1-1.41.7-1.31.3
Water consumed over 24 hours0.10.31.10.2-0.6-0.4-0.10.2-0.4-0.40.1-1.10.9
Number of responses in last shaping day0.40.51.9-0.30.70.60.4-0.10.50.7-0.21.4-1.1