Btaf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA XM_006231332.4 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 3.3e-03 1.2e-03 7.6e-03 5.2e-03
2 Liver isoform ratio XM_039085850.1 0.02 0.01 8.8e-03 0 0.01 0 0 1.6e-01 2.6e-02 1.5e-01 1.3e-01
3 PL alternative TSS XM_039085850.1 0.02 0.02 4.1e-03 0.02 0.02 0.01 0.01 2.3e-03 5.2e-03 8.7e-03 7.0e-03
4 Brain alternative polyA XM_006231332.4 0.05 0.03 6.8e-05 0.04 0.03 0.03 0.03 1.4e-04 1.2e-03 3.4e-04 4.3e-04
5 Brain alternative polyA XM_039085850.1 0.05 0.03 6.2e-05 0.04 0.03 0.04 0.04 1.1e-04 9.8e-04 3.2e-04 2.6e-04
6 Brain mRNA stability Btaf1 0.09 0.06 1.3e-07 0.06 0.07 0.07 0.06 4.4e-06 1.9e-07 5.7e-07 1.4e-06
7 Adipose gene expression Btaf1 0.03 0.03 1.1e-03 0.02 0.02 0.01 0.02 9.6e-04 3.5e-03 5.2e-02 4.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density6.911.518.0-4.23.83.63.3-3.3-3.0-2.0
Area under the delay curve0.40.40.70.9-0.6-0.7-0.80.80.40.1
BMI with tail0.10.20.3-0.50.40.60.6-0.6-0.3-0.3
BMI without tail0.00.10.1-0.30.20.30.3-0.3-0.10.1
Body weight1.35.66.6-1.82.32.62.4-2.4-2.5-2.5
Weight adjusted by age0.20.20.5-0.1-0.2-0.7-0.30.30.50.7
Bone surface3.56.110.3-3.22.72.82.4-2.4-2.0-1.2
Bone volume5.28.812.3-3.53.33.32.9-2.9-2.7-2.0
Breakpoint value in progressive ratio session1.01.12.2-0.71.10.90.9-0.9-1.3-1.5
Number of licking bursts2.32.73.92.0-1.8-1.9-1.61.61.50.9
Context. condit. distance diff. score2.73.24.3-1.41.81.71.7-1.7-2.1-2.1
Locomotion velocity, session 13.63.96.41.4-2.0-1.9-1.61.62.42.5
Locomotion distance, session 10.20.30.50.4-0.6-0.5-0.50.50.70.5
Locomotion velocity, session 20.80.91.40.9-1.1-0.9-0.70.71.21.0
Locomotion distance, session 20.20.30.70.9-0.6-0.3-0.60.60.3-0.2
Locomotion velocity, session 30.30.30.5-0.30.50.40.7-0.7-0.6-0.6
Locomotion distance, session 31.01.12.4-0.30.91.00.9-0.9-1.3-1.5
Stereotopy head waving bouts, day 30.20.31.2-0.2-0.3-0.2-0.10.10.71.1
Stereotopy head waving duration, day 30.20.20.9-0.2-0.2-0.3-0.10.10.60.9
Locomotion velocity, session 71.01.13.3-0.41.00.50.7-0.7-1.3-1.8
Locomotion distance, session 71.01.23.4-0.61.10.70.7-0.7-1.4-1.8
Stereotopy head waving bouts, day 70.20.20.60.1-0.4-0.2-0.30.30.50.8
Stereotopy head waving duration, day 70.20.20.9-0.3-0.20.20.1-0.10.41.0
Locomotion velocity, session 80.30.40.4-0.60.60.60.7-0.7-0.6-0.7
Locomotion distance, session 80.60.82.5-0.30.90.60.6-0.6-1.2-1.6
Degree of sensitization distance0.20.20.40.3-0.2-0.6-0.50.50.1-0.3
Degree of sensitization stereotypy0.10.10.2-0.30.10.30.2-0.20.00.4
Conditioned locomotion0.80.91.1-0.91.00.90.9-0.9-1.0-1.0
Cocaine response after cond. corrected0.00.00.0-0.20.00.2-0.10.10.10.2
Cocaine response after cond. not corrected0.10.10.3-0.10.30.50.1-0.1-0.5-0.6
Cocaine response before conditioning0.10.20.50.6-0.2-0.0-0.20.2-0.3-0.7
Saline control response0.10.10.40.6-0.1-0.3-0.20.2-0.1-0.7
Bone: connectivity density3.45.310.7-3.32.62.52.2-2.2-1.8-0.9
Bone: cortical apparent density2.33.03.41.5-1.7-1.8-1.81.81.81.7
Bone: cortical area3.95.86.8-1.92.42.62.4-2.4-2.5-2.6
Bone: cortical porosity0.10.10.20.5-0.4-0.5-0.30.30.30.2
Bone: cortical porosity0.00.00.00.00.00.00.1-0.1-0.1-0.1
Bone: cortical thickness0.40.61.7-0.10.60.80.5-0.5-0.9-1.3
Bone: cortical thickness0.40.40.80.9-0.6-0.8-0.80.80.3-0.2
Bone: cortical tissue density2.43.13.41.5-1.8-1.8-1.81.81.81.8
Condit. Reinf. active minus inactive responses0.60.71.71.3-1.0-0.9-0.70.70.70.3
Condit. Reinf. active-inactive response ratio1.21.21.71.1-1.3-1.1-0.90.91.31.3
Condit. Reinf. active responses0.20.20.70.40.10.10.3-0.3-0.5-0.9
Condit. Reinf. inactive responses1.21.42.9-0.71.21.01.0-1.0-1.4-1.7
Incentive salience index mean0.70.92.71.7-1.1-0.9-0.70.70.5-0.1
Condit. Reinf. lever presses0.91.33.41.8-1.3-1.2-0.90.90.7-0.1
Condit. Reinf. active minus inactive responses0.50.72.4-0.00.70.60.3-0.3-1.1-1.6
Condit. Reinf. active-inactive response ratio0.10.10.30.30.1-0.1-0.10.1-0.3-0.6
Condit. Reinf. active responses1.82.43.9-1.11.61.61.3-1.3-1.8-2.0
Condit. Reinf. inactive responses1.72.13.0-1.31.41.71.4-1.4-1.5-1.3
Condit. Reinf. lever presses0.10.20.3-0.40.40.50.5-0.5-0.4-0.3
Condit. Reinf. lever reinforcers received1.01.52.6-0.81.21.31.0-1.0-1.5-1.6
Conditioned reinforcement - actives3.03.03.5-1.71.71.81.9-1.9-1.6-1.3
Conditioned reinforcement - inactives2.62.94.0-2.01.81.81.9-1.9-1.4-0.9
Conditioned locomotion1.11.32.6-1.61.11.31.3-1.3-0.70.0
Patch foraging indifference point 0 sec0.00.10.20.1-0.20.2-0.20.20.30.5
Patch foraging indifference point AUC1.01.22.11.5-1.3-0.9-1.21.20.90.5
Delay disc. indifference point, 0s delay0.40.42.00.40.3-0.1-0.30.3-0.8-1.4
Delay disc. indifference point, 16s delay0.00.00.1-0.20.20.20.3-0.3-0.1-0.0
Delay disc. indifference point, 2s delay0.30.30.60.3-0.4-0.7-0.80.80.50.4
Delay disc. indifference point, 24s delay0.70.71.91.4-1.0-0.8-0.80.80.50.2
Delay disc. indifference point, 4s delay0.30.30.40.7-0.2-0.3-0.60.6-0.2-0.7
Delay disc. indifference point, 8s delay2.62.63.01.7-1.7-1.7-1.71.71.61.3
Indifference point function ln k1.82.43.1-1.81.81.51.6-1.6-1.5-1.1
Indifference point function log k1.82.43.1-1.81.81.51.6-1.6-1.5-1.1
Patch foraging total patch changes 0 sec0.00.10.20.0-0.20.3-0.10.10.20.4
Patch foraging total patch changes 12 sec1.82.32.91.6-1.7-1.2-1.61.61.61.4
Patch foraging total patch changes 18 sec0.30.40.60.8-0.8-0.5-0.60.60.60.4
Patch foraging total patch changes 24 sec0.20.20.50.7-0.5-0.2-0.60.60.20.1
Patch foraging total patch changes 6 sec0.91.42.11.2-1.4-0.7-1.01.01.41.3
Patch foraging time to switch 0 sec0.91.42.01.1-1.2-1.4-1.21.21.21.1
Patch foraging water rate 0 sec0.30.50.9-0.60.71.00.6-0.6-0.8-0.8
Patch foraging water rate 12 sec0.71.11.6-0.90.91.11.3-1.3-0.9-0.7
Patch foraging water rate 18 sec1.31.82.4-1.11.31.61.3-1.3-1.4-1.3
Patch foraging water rate 24 sec2.02.83.8-1.01.51.81.7-1.7-1.8-2.0
Patch foraging water rate 6 sec0.10.10.3-0.60.40.40.4-0.4-0.20.2
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.00.20.10.1-0.1-0.4-0.6
Distance traveled before self-admin0.20.20.50.7-0.4-0.5-0.50.50.1-0.3
Distance traveled after self-admin0.20.20.6-0.80.40.00.3-0.30.10.5
Extensor digitorum longus weight0.52.16.0-0.41.31.10.9-0.9-1.9-2.4
Bone: elastic displacement3.64.16.41.2-1.9-2.1-1.91.92.32.5
Bone: elastic work2.02.64.40.6-1.3-1.5-1.81.81.82.1
Bone: endosteal estimation4.810.513.6-3.73.53.43.4-3.4-2.9-2.1
Bone: endosteal perimeter5.511.314.6-3.83.63.53.6-3.6-3.0-2.2
Epididymis fat weight0.30.61.6-0.00.50.80.8-0.8-0.8-1.3
Delta time in closed arm before/after self-admin0.40.41.41.2-0.8-0.4-0.30.30.3-0.1
Delta time in open arm before/after self-admin0.10.10.2-0.20.2-0.3-0.40.4-0.1-0.2
Diff in mean of infusions in LGA sessions0.30.41.0-0.10.50.60.4-0.4-0.7-1.0
Delay discount exponential model param0.40.50.9-0.90.70.70.8-0.8-0.5-0.2
Extinction: sum of active levers before priming0.40.40.7-0.20.50.80.6-0.6-0.7-0.9
Active lever presses in extinction session 61.31.32.3-0.91.20.90.9-0.9-1.3-1.5
Bone: final force1.11.82.6-1.21.41.61.3-1.3-1.3-1.2
Bone: final moment0.91.52.3-1.31.31.51.2-1.2-1.1-0.8
Food consumed during 24 hour testing period0.00.00.10.3-0.20.20.2-0.20.10.0
Glucose0.10.10.4-0.20.30.60.3-0.3-0.4-0.3
Heart weight0.20.21.0-0.1-0.30.30.3-0.30.61.0
Delay discount hyperbolic model param0.50.50.8-0.90.70.80.9-0.9-0.5-0.3
Intermittent access intake day 1-15 change2.42.34.2-2.01.61.81.6-1.6-1.1-0.4
Intermittent access intake escalation2.12.13.8-2.01.51.81.5-1.5-1.0-0.3
Intermittent access intake escalation 20.80.81.7-1.30.91.00.9-0.9-0.6-0.3
Intermitt. access day 1 inactive lever presses0.10.10.4-0.40.1-0.3-0.10.10.30.6
Intermitt. access day 15 inactive lever presses1.41.53.7-1.91.31.11.3-1.3-0.50.3
Intermitt. access escalation Index0.20.10.40.7-0.3-0.3-0.20.2-0.0-0.6
Intermittent access day 1 total infusions1.31.52.0-1.01.21.21.2-1.2-1.3-1.4
Intermittent access day 15 total infusions5.15.77.4-2.52.42.72.6-2.6-2.1-1.7
Intermittent access terminal intake (last 3 days)2.83.03.8-1.91.71.91.9-1.9-1.5-1.1
Intermittent access total infusions2.72.93.4-1.61.71.81.8-1.8-1.6-1.5
Intermittent access day 1 locomotion0.80.81.2-0.71.00.90.8-0.8-1.0-1.1
Intermittent access day 15 total locomotion1.31.42.7-1.61.31.41.1-1.1-0.9-0.4
Intermittent access total locomotion0.40.40.6-0.70.70.60.6-0.6-0.7-0.7
Intermittent access standard deviation1.51.62.4-1.51.21.51.4-1.4-1.0-0.6
Left kidney weight0.61.62.5-0.40.91.61.3-1.3-1.3-1.5
Right kidney weight0.10.40.80.40.10.80.5-0.5-0.6-0.9
Cocaine induced anxiety0.20.20.50.5-0.2-0.7-0.40.4-0.0-0.4
Post-drug Anxiety0.40.40.80.4-0.5-0.9-0.60.60.70.6
Baseline Anxiety0.10.10.6-0.2-0.2-0.0-0.10.10.50.8
Tail length0.51.73.3-0.71.31.21.1-1.1-1.6-1.8
Length with tail1.65.78.7-1.52.32.62.2-2.2-2.7-2.9
Length without tail2.24.78.4-1.22.12.31.9-1.9-2.6-2.9
Times rat made contact with spout0.10.10.50.30.1-0.4-0.00.0-0.3-0.7
Lifetime Intake2.02.22.7-1.41.51.61.6-1.6-1.4-1.3
Liver weight, left3.75.97.7-1.62.32.52.5-2.5-2.7-2.8
Liver weight, right0.91.54.1-0.21.01.01.0-1.0-1.5-2.0
Locomotor activity0.50.80.90.7-0.9-0.9-0.90.91.00.9
Locomotor testing distance0.81.31.60.9-1.2-1.1-1.11.11.21.3
Locomotor testing rearing0.10.10.4-0.00.30.20.1-0.1-0.4-0.6
Locomotion in novel chamber1.21.52.8-1.71.51.11.1-1.1-1.2-0.8
Locomotion in novel chamber post-restriction3.03.66.4-1.52.01.81.4-1.4-2.2-2.5
Fecal boli incidents, locomotor time 10.10.10.30.10.2-0.0-0.00.0-0.4-0.5
Change in fecal boli incidents, locomotor task0.00.00.00.1-0.2-0.1-0.10.10.20.1
Time >=10cm from walls, locomotor time 14.94.98.6-1.52.22.21.9-1.9-2.6-2.9
Bouts of movement, locomotor time 10.30.40.7-0.60.70.40.5-0.5-0.7-0.8
Total resting periods, locomotor time 10.50.51.0-0.60.80.60.5-0.5-0.8-1.0
Rest time, locomotor task time 10.10.10.2-0.40.1-0.30.4-0.40.10.4
Distance moved, locomotor task time 10.40.40.90.8-0.3-0.1-1.01.0-0.1-0.6
Vertical activity count, locomotor time 10.10.10.40.10.10.6-0.20.2-0.1-0.3
Time >=10cm from walls, locomotor time 20.50.52.40.10.50.30.3-0.3-0.9-1.5
Bouts of movement, locomotor time 22.12.33.41.8-1.6-1.9-1.51.51.40.6
Total resting periods, locomotor time 22.22.33.51.8-1.6-1.9-1.51.51.40.6
Rest time, locomotor task time 20.00.10.20.20.1-0.20.1-0.1-0.3-0.4
Distance moved, locomotor task time 20.10.20.40.20.20.4-0.30.3-0.5-0.7
Vertical activity count, locomotor time 20.30.30.40.4-0.6-0.2-0.60.60.60.6
Light reinforcement 10.10.20.9-0.90.60.20.4-0.4-0.20.3
Light reinforcement 23.34.46.21.3-1.9-2.3-2.02.02.32.5
Bone: marrow area5.111.014.4-3.83.63.53.5-3.5-3.0-2.1
Bone: maximum diameter9.717.820.5-4.44.44.34.5-4.5-3.9-3.2
Bone: maximum force2.54.35.8-2.22.22.42.1-2.1-1.9-1.5
Bone: maximum moment2.13.75.2-2.32.02.32.0-2.0-1.6-1.0
Mean time between licks in bursts1.21.63.00.9-1.3-1.0-1.11.11.51.7
Mean num. licks in bursts1.92.32.9-1.61.71.61.4-1.4-1.5-1.3
Cd content in liver0.20.20.60.4-0.6-0.3-0.20.20.70.8
Co content in liver1.31.54.20.3-1.1-1.0-0.90.91.62.0
Cu content in liver3.74.57.51.2-2.0-2.0-2.12.12.42.7
Fe content in liver4.85.87.32.3-2.4-2.4-2.72.72.22.0
K content in liver0.70.71.30.9-0.6-1.1-1.01.00.4-0.1
Mg content in liver1.61.72.21.4-1.3-1.5-1.41.41.10.8
Mn content in liver1.92.12.61.6-1.5-1.5-1.61.61.30.9
Na content in liver2.12.34.12.0-1.5-1.7-1.71.71.00.1
Rb content in liver0.10.10.3-0.00.30.1-0.10.1-0.5-0.5
Se content in liver25.831.636.25.5-6.0-5.6-5.65.65.85.2
Sr content in liver0.40.41.0-1.00.30.40.4-0.40.30.9
Zn content in liver10.811.913.93.7-3.6-3.6-3.73.73.12.4
Bone: minimum diameter8.516.020.1-3.84.04.54.2-4.2-3.9-3.3
Time in familiar zone, hab. session 10.00.00.2-0.40.20.10.1-0.10.10.2
Time in novel zone, hab. session 10.60.60.80.9-0.8-0.7-0.80.80.50.5
Total zone transitions, hab. session 10.00.00.1-0.30.20.20.2-0.2-0.1-0.0
Total locomotion distance, hab. session 10.71.01.61.0-0.8-1.1-1.31.30.70.4
Locomotion velocity, hab. session 11.01.42.31.3-1.0-1.3-1.51.50.80.3
Time in familiar zone, hab. session 20.30.30.60.3-0.6-0.5-0.30.30.80.7
Time in novel zone, hab. session 20.00.00.0-0.20.20.20.0-0.0-0.20.1
Total zone transitions, hab. session 20.40.50.70.6-0.8-0.5-0.60.60.90.9
Total locomotion distance, hab. session 20.70.91.30.9-1.0-0.9-1.11.10.90.7
Locomotion velocity, hab. session 20.70.91.41.1-0.9-1.0-1.21.20.70.4
Novel to familiar place preference ratio0.40.40.8-0.80.90.40.4-0.4-0.9-0.6
Novelty place preference0.50.51.0-1.01.00.50.4-0.4-0.9-0.6
Time in novel zone, NPP test0.30.30.6-0.80.80.40.3-0.3-0.7-0.4
Total zone transitions, NPP test0.50.71.51.2-1.0-0.8-0.70.70.70.3
Total locomotion distance, NPP test1.62.23.01.7-1.5-1.5-1.71.71.20.8
Locomotion velocity, NPP test1.31.93.01.7-1.4-1.4-1.61.61.00.5
Intraocular pressure0.30.40.9-0.90.70.60.4-0.4-0.4-0.4
Delta distance traveled before/after self-admin1.31.42.6-1.61.21.11.3-1.3-0.8-0.1
Delta ambulatory time before/after self-admin2.42.64.1-2.01.71.61.8-1.8-1.3-0.6
Parametrial fat weight0.40.82.0-0.30.80.80.8-0.8-1.0-1.4
Pavlov. Cond. lever latency0.40.51.6-1.30.50.70.4-0.40.11.0
Pavlov. Cond. magazine entry latency0.81.02.71.6-1.2-0.9-0.90.90.80.1
Pavlov. Cond. change in total contacts1.01.12.61.6-1.3-0.9-0.90.90.90.4
Pavlov. Cond. index score0.50.62.21.5-0.7-0.6-0.40.4-0.0-0.9
Pavlov. Cond. latency score0.50.72.21.5-0.6-0.5-0.40.4-0.2-1.3
Pavlov. Cond. lever contacts0.50.62.21.5-0.7-0.7-0.50.5-0.0-0.9
Pavlov. Cond. magazine entry number0.20.20.9-0.90.70.40.1-0.1-0.40.1
Pavlov. Cond. intertrial magazine entries0.50.61.0-0.60.90.80.6-0.6-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.93.11.7-1.0-0.8-0.70.70.2-0.7
Pavlov. Cond. response bias0.70.92.31.5-1.2-0.9-0.70.70.80.3
Pavlov. Cond. lever latency0.10.10.6-0.00.40.10.1-0.1-0.5-0.8
Pavlov. Cond. magazine entry latency0.50.61.41.2-1.0-0.6-0.60.60.60.3
Pavlov. Cond. change in total contacts0.10.10.40.6-0.3-0.1-0.20.20.0-0.2
Pavlov. Cond. index score0.00.00.20.4-0.20.10.0-0.00.1-0.1
Pavlov. Cond. latency score0.00.00.00.2-0.00.20.2-0.2-0.1-0.2
Pavlov. Cond. lever contacts0.00.00.10.0-0.20.10.1-0.10.20.3
Pavlov. Cond. magazine entry number1.21.53.1-1.81.41.21.2-1.2-1.0-0.6
Pavlov. Cond. intertrial magazine entries1.01.43.0-0.71.21.00.9-0.9-1.4-1.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.6-0.3-0.1-0.10.10.1-0.1
Pavlov. Cond. response bias0.40.51.01.0-0.9-0.6-0.60.60.70.5
Time in closed arm before self-admin0.20.20.40.2-0.3-0.6-0.50.50.40.5
Time in closed arm after self-admin0.90.92.61.6-1.1-0.9-0.90.90.5-0.1
Time in open arm before self-admin0.10.10.30.1-0.30.00.0-0.00.40.6
Time in open arm after self-admin0.60.61.7-1.31.00.60.7-0.7-0.5-0.2
Bone: periosteal estimation6.112.714.5-3.73.83.83.7-3.7-3.4-2.8
Bone: periosteal perimeter6.110.210.9-3.13.33.33.3-3.3-3.2-2.8
Bone: post-yield work3.95.37.9-1.92.12.52.8-2.8-2.1-1.7
Progressive ratio test 1 active lever presses1.71.82.4-1.51.41.51.4-1.4-1.2-1.1
Progressive ratio test 1 breakpoint1.51.62.1-1.41.31.51.3-1.3-1.1-0.9
Progressive ratio test 1 inactive lever presses2.32.53.4-1.71.61.61.8-1.8-1.3-1.0
Progressive ratio test 2 active lever presses4.75.16.5-2.52.42.52.3-2.3-2.0-1.5
Progressive ratio test 2 breakpoint5.76.48.3-2.92.72.72.6-2.6-2.3-1.7
Progressive ratio test 2 inactive lever presses2.22.54.3-2.11.71.51.7-1.7-1.2-0.6
Incentive Sensitization - Responses4.44.56.1-2.52.32.22.2-2.2-1.9-1.4
Incentive Sensitization - Breakpoint4.64.76.4-2.52.32.32.3-2.3-1.9-1.4
Sum of active levers in priming session hrs 5-60.60.60.90.2-0.6-0.8-0.80.80.91.0
Progressive ratio0.60.72.0-0.30.70.80.6-0.6-1.1-1.4
Food seeking constrained by brief footshock2.93.54.6-1.51.82.22.0-2.0-1.9-1.7
Seeking ratio, punishment vs. effort0.00.00.1-0.20.10.20.3-0.30.00.2
Retroperitoneal fat weight0.20.60.9-0.50.70.71.0-1.0-0.7-0.9
Reaction time number correct1.01.52.2-1.41.50.91.1-1.1-1.3-1.1
Reaction time mean minus median0.40.51.0-0.70.20.71.0-1.00.00.5
Reaction time mean minus median AUC0.20.21.0-0.3-0.20.00.3-0.30.61.0
Reaction time num false alarms0.71.03.0-0.41.00.80.5-0.5-1.3-1.7
Reaction time num false alarms AUC0.40.62.0-0.10.60.60.3-0.3-1.0-1.4
Reaction time trials correct on left1.01.52.2-1.41.50.91.1-1.1-1.3-1.1
Reaction time trials on left1.01.52.2-1.41.50.91.1-1.1-1.3-1.1
Reaction time mean1.82.53.81.4-1.8-1.4-1.31.31.81.9
Reaction time mean AUC2.43.24.81.6-2.0-1.6-1.51.52.02.2
Median of all reaction times3.04.25.11.8-2.2-1.9-2.02.02.22.3
Reaction time omissions0.00.00.10.2-0.3-0.1-0.20.20.20.3
Reaction time false alarm rate0.10.20.80.30.20.3-0.00.0-0.5-0.9
Reaction time premature initiation rate1.52.12.5-1.11.31.61.6-1.6-1.4-1.5
Reaction time premature initiations3.65.15.6-2.02.32.32.4-2.4-2.3-2.2
Std. dev. reaction times0.30.51.90.2-0.7-0.10.1-0.10.91.4
Reaction time trials completed1.01.52.2-1.41.50.91.1-1.1-1.3-1.1
Reaction time trials AUC0.71.01.5-1.11.20.70.8-0.8-1.1-1.1
Run reversals in cocaine runway, females0.40.41.00.0-0.4-0.7-0.40.40.81.0
Run reversals in cocaine runway, males0.00.00.20.4-0.3-0.1-0.20.20.1-0.1
Latency to leave start box in cocaine runway0.60.60.9-0.80.90.80.5-0.5-0.9-0.9
Latency to leave start box in cocaine runway, F0.10.10.3-0.30.40.30.1-0.1-0.4-0.5
Latency to leave start box in cocaine runway, M0.70.71.0-0.91.01.00.6-0.6-0.9-0.8
Std. dev. time between licks in bursts2.63.14.01.6-1.9-1.6-1.61.62.02.0
Total sessions with >9 infusions0.40.40.8-0.60.40.80.9-0.9-0.4-0.2
Short access day 1 total inactive lever presses0.70.82.4-1.60.80.70.9-0.9-0.10.6
Short access day 10 total inactive lever presses1.01.11.60.9-1.0-1.3-1.01.01.11.1
Short access day 1 total infusions0.00.00.10.0-0.10.20.0-0.00.00.1
Short access day 10 total infusions0.00.00.1-0.1-0.00.30.3-0.30.00.1
Short access total infusions0.80.91.3-0.90.91.21.1-1.1-0.9-0.8
Short access day 1 locomotion0.00.00.20.4-0.3-0.0-0.10.10.1-0.0
Short access day 10 total locomotion0.10.10.30.3-0.3-0.5-0.50.50.30.0
Short access total locomotion0.30.30.40.5-0.5-0.6-0.60.60.60.5
One hour access (0.3 mA shock)9.310.912.4-3.53.43.53.5-3.5-3.1-2.6
Compulsive drug intake1.41.42.4-0.91.21.11.0-1.0-1.3-1.6
One hour access (shock baseline)2.22.53.2-1.81.61.71.7-1.7-1.4-1.0
Social response proportion0.10.10.4-0.60.2-0.10.3-0.30.30.6
Social responses0.70.92.0-1.40.80.91.1-1.1-0.30.3
Social time0.70.91.31.1-1.1-0.9-0.80.81.01.0
Soleus weight0.82.44.1-2.01.61.71.7-1.7-1.1-0.4
Bone: stiffness3.75.97.5-1.82.42.52.4-2.4-2.6-2.7
Tibialis anterior weight0.72.47.7-0.41.40.80.9-0.9-2.1-2.8
Time to tail flick, vehicle, before self-admin1.01.11.70.6-0.9-1.1-1.01.01.21.3
Time to tail flick, vehicle, after self-admin0.91.03.5-0.20.90.60.5-0.5-1.4-1.9
Time to tail flick, test, before self-admin2.62.63.7-1.31.71.51.4-1.4-1.9-1.9
Time to tail flick, test, after self-admin0.30.30.80.6-0.5-0.9-0.50.50.50.3
Delta time to tail flick, vehicle, before/after SA4.24.110.0-1.02.01.71.5-1.5-2.6-3.2
Delta time to tail flick, test, before/after SA0.20.20.40.6-0.5-0.7-0.30.30.50.2
Tibia length0.10.20.4-0.50.50.60.4-0.4-0.5-0.4
Ambulatory time before self-admin1.01.01.51.2-1.0-1.0-1.21.20.70.3
Ambulatory time after self-admin0.20.20.7-0.90.60.20.5-0.5-0.20.1
Bone: tissue strength0.30.31.6-0.1-0.4-0.0-0.10.10.71.3
Total heroin consumption1.11.21.5-1.11.21.21.1-1.1-1.2-1.0
Bone: trabecular number5.07.813.0-3.63.03.12.8-2.8-2.3-1.3
Bone: trabecular spacing2.02.65.22.3-1.8-1.7-1.51.51.30.5
Bone: trabecular thickness4.35.27.8-2.82.52.62.2-2.2-2.1-1.4
Bone: trabecular tissue density1.52.12.6-1.51.61.31.4-1.4-1.4-1.4
Water consumed over 24 hours0.30.40.91.0-0.4-0.7-0.60.6-0.1-0.7
Number of responses in last shaping day1.51.62.6-1.61.31.41.3-1.3-1.0-0.4