Hub : Genes

Brme1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Brme1 0.06 0.03 7.8e-05 0.04 0.05 0.05 0.04 5.3e-05 3.5e-05 3.5e-05 4.6e-05
2 Liver mRNA stability Brme1 0.1 0.05 2.0e-11 0.11 0.09 0.1 0.1 1.9e-12 1.6e-10 9.2e-11 3.4e-11
3 BLA mRNA stability Brme1 0.09 0.05 8.7e-03 0.02 0.02 0.02 0.02 3.9e-02 1.8e-02 2.9e-02 2.3e-02
4 Adipose mRNA stability Brme1 0.12 0.05 7.2e-09 0.07 0.08 0.07 0.04 2.5e-08 8.3e-09 2.0e-08 2.3e-05
5 NAcc mRNA stability Brme1 0.02 0.01 1.2e-03 0.01 0.01 0.01 0 3.8e-02 9.6e-03 4.2e-02 7.1e-02
6 pVTA mRNA stability Brme1 0.05 0.03 3.3e-03 0.03 0.01 0.01 0.02 3.6e-03 2.9e-02 5.6e-02 1.5e-02
7 IC gene expression Brme1 0.13 0.09 6.5e-03 0.06 0 0.04 0.01 2.2e-03 3.0e-01 6.3e-03 1.6e-01
8 NAcc gene expression Brme1 0.02 0.01 2.9e-03 0.01 0.02 0.02 0.02 1.9e-03 1.4e-03 1.3e-03 7.0e-04
9 Brain gene expression Brme1 0.04 0.02 4.2e-03 0.01 0 0 0 4.4e-02 1.0e-01 1.7e-01 9.9e-02
10 BLA intron excision ratio chr19_40905029_40916187 0.1 0.05 9.6e-05 0.09 0.06 0.06 0.06 2.4e-05 5.5e-04 4.5e-04 3.4e-04
11 Liver gene expression Brme1 0.07 0.04 1.3e-04 0.03 0.01 0.01 0.01 1.3e-04 1.7e-02 3.9e-02 1.1e-02
12 BLA isoform ratio XM_039098080.2 0.05 0.03 7.6e-03 0.03 0.03 0.01 0.02 1.4e-02 1.5e-02 7.2e-02 3.7e-02
13 Liver isoform ratio NM_001400966.1 0.02 0.02 9.2e-03 0 0 -0 0 7.6e-02 1.4e-01 5.5e-01 3.2e-01
14 Adipose isoform ratio XR_005496718.2 0.12 0.05 1.8e-10 0.09 0.08 0.07 0.08 6.5e-10 8.7e-09 1.8e-08 2.3e-09
15 Adipose alternative polyA XM_063277963.1 0.03 0.02 3.8e-04 0.03 0.02 0.04 0.03 6.2e-04 2.3e-03 6.4e-05 3.6e-04
16 pVTA gene expression Brme1 0.06 0.03 2.2e-05 0.03 0.06 0.05 0.06 2.0e-03 6.7e-06 4.7e-05 1.3e-05
17 PL intron excision ratio chr19_40902378_40904855 0.06 0.03 3.2e-05 0.04 0.04 0.03 0.04 1.5e-05 8.1e-05 2.8e-04 9.4e-05
18 Adipose alternative polyA NM_001400966.1 0.04 0.02 4.2e-04 0.03 0.02 0.04 0.03 7.6e-04 2.9e-03 8.2e-05 5.0e-04
19 PL gene expression Brme1 0.12 0.06 8.8e-09 0.07 0.08 0.09 0.09 1.1e-07 2.3e-09 1.0e-09 1.4e-09
20 Adipose gene expression Brme1 0.04 0.02 2.0e-03 0.01 0.02 0.01 0.01 4.7e-02 4.0e-03 1.3e-02 9.0e-03
21 BLA gene expression Brme1 0.25 0.09 1.4e-09 0.13 0.16 0.14 0.16 1.5e-07 7.8e-09 5.7e-08 1.0e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density2.03.79.52.63.1-2.7-2.7-2.21.9-2.4-0.90.7-3.00.8-2.3-2.2-1.2-1.91.0-1.51.80.4-0.20.8
Area under the delay curve0.20.41.3-0.6-0.50.20.60.2-0.2-1.10.8-0.9-0.8-0.9-0.6-0.5-0.3-0.30.9-0.30.3-0.70.60.4
BMI with tail1.34.713.7-2.3-3.12.51.73.6-3.33.70.6-0.71.9-0.62.51.7-0.92.6-1.72.2-2.40.3-1.0-0.1
BMI without tail0.10.41.7-0.3-0.50.30.41.0-0.81.00.6-0.7-0.6-0.7-0.1-0.6-1.00.10.2-0.2-0.0-0.50.31.3
Body weight0.10.44.00.1-0.60.00.40.3-0.02.0-0.30.20.90.30.80.30.40.2-1.00.0-0.1-0.0-0.10.9
Weight adjusted by age0.10.31.1-1.1-0.90.70.40.4-0.4-0.60.3-0.10.4-0.10.30.60.40.60.20.5-0.60.1-0.0-1.0
Bone surface2.04.08.62.32.6-2.2-1.4-2.71.9-2.20.5-0.5-2.7-0.5-2.9-2.30.6-2.22.0-2.62.1-1.21.41.7
Bone volume2.04.08.62.72.9-2.4-1.9-2.82.0-2.00.1-0.3-2.7-0.1-2.9-2.20.5-2.31.7-2.42.1-0.81.01.4
Breakpoint value in progressive ratio session1.22.15.30.70.0-0.5-1.20.30.11.7-2.32.01.52.11.61.4-0.60.6-2.31.6-0.52.1-2.0-1.2
Number of licking bursts0.20.53.50.60.5-0.9-0.6-0.00.7-0.1-0.80.6-0.70.60.1-1.0-1.9-0.7-0.4-0.20.80.4-0.41.0
Context. condit. distance diff. score0.60.72.6-1.3-1.61.21.51.3-0.30.80.3-0.21.2-0.21.40.6-0.2-0.1-0.50.70.2-0.20.20.1
Locomotion velocity, session 10.70.82.51.61.4-1.5-1.3-1.20.8-0.1-0.40.2-1.00.3-1.1-0.90.0-0.80.2-0.90.8-0.2-0.10.8
Locomotion distance, session 10.40.51.51.10.7-1.0-0.9-0.30.30.5-1.20.6-0.20.80.4-0.5-1.0-0.0-0.8-0.00.10.6-0.70.5
Locomotion velocity, session 20.40.51.50.80.9-1.0-0.8-0.60.9-0.8-0.60.2-1.00.2-0.3-1.0-1.2-0.80.1-0.40.80.1-0.10.6
Locomotion distance, session 20.50.61.90.6-0.0-0.5-0.50.30.01.4-1.40.80.60.91.20.0-1.10.4-1.40.6-0.21.0-1.00.3
Locomotion velocity, session 30.10.20.5-0.1-0.20.40.50.1-0.40.10.7-0.5-0.1-0.5-0.4-0.10.5-0.10.6-0.30.1-0.60.60.3
Locomotion distance, session 31.92.15.10.20.4-0.40.9-0.80.8-1.51.4-1.2-1.7-1.3-1.6-2.1-0.5-1.72.0-1.91.7-1.72.02.3
Stereotopy head waving bouts, day 31.41.65.0-1.4-0.91.31.60.5-1.1-0.02.2-2.2-0.2-2.0-0.9-0.11.30.31.6-0.8-0.4-1.81.60.7
Stereotopy head waving duration, day 30.50.61.6-1.1-0.81.01.00.8-1.00.11.2-1.3-0.0-1.1-0.10.10.30.60.6-0.1-0.6-0.80.60.2
Locomotion velocity, session 70.20.31.0-0.3-0.70.51.00.5-0.10.50.5-0.30.1-0.40.2-0.4-0.4-0.40.3-0.20.5-0.60.71.0
Locomotion distance, session 70.20.30.80.80.4-0.7-0.5-0.30.50.4-0.90.8-0.00.80.3-0.3-0.7-0.2-0.50.00.30.5-0.40.3
Stereotopy head waving bouts, day 71.82.14.7-0.60.10.21.2-0.40.4-1.71.8-1.8-1.5-1.8-1.5-1.6-0.1-1.32.2-1.61.3-2.02.01.7
Stereotopy head waving duration, day 71.51.83.70.10.7-0.40.4-0.70.7-1.91.3-1.2-1.8-1.3-1.7-1.8-0.4-1.51.9-1.61.5-1.51.61.6
Locomotion velocity, session 80.20.31.30.7-0.0-0.4-0.1-0.30.61.2-0.70.50.80.60.60.20.4-0.3-0.80.00.40.2-0.30.2
Locomotion distance, session 80.40.62.4-0.1-0.70.10.40.80.11.3-1.00.60.90.81.60.1-1.2-0.1-1.30.70.20.7-0.60.4
Degree of sensitization distance1.71.94.30.5-0.1-0.2-1.00.4-0.21.6-1.81.61.51.71.61.50.01.2-2.11.5-1.21.8-1.9-1.6
Degree of sensitization stereotypy1.01.12.5-0.40.00.10.9-0.20.2-1.31.2-1.3-1.2-1.5-1.0-1.3-0.4-1.01.6-1.10.9-1.51.51.3
Conditioned locomotion0.10.10.40.60.2-0.4-0.3-0.50.40.2-0.40.30.10.4-0.1-0.10.3-0.3-0.3-0.20.30.2-0.10.1
Cocaine response after cond. corrected0.71.03.80.1-0.70.2-0.20.7-0.21.9-1.11.11.51.21.51.1-0.00.5-1.71.1-0.41.2-1.2-0.7
Cocaine response after cond. not corrected1.01.54.20.3-0.5-0.0-0.60.7-0.02.0-1.51.51.41.61.61.1-0.40.4-2.01.4-0.31.6-1.6-0.9
Cocaine response before conditioning0.30.30.90.40.7-0.7-0.5-0.50.6-0.7-0.10.1-1.00.0-0.6-0.8-0.7-0.70.4-0.50.7-0.00.10.5
Saline control response1.92.66.32.51.6-2.3-2.0-1.21.6-0.3-2.52.5-0.52.50.4-0.9-1.8-0.9-1.4-0.01.01.8-1.40.3
Bone: connectivity density3.55.514.82.63.4-2.9-2.4-2.72.3-3.2-0.30.1-3.80.2-3.1-3.1-1.3-2.61.9-2.32.4-0.30.71.7
Bone: cortical apparent density0.50.72.2-1.4-0.70.71.01.1-0.7-0.71.0-1.1-0.9-1.0-0.1-0.9-1.5-0.10.8-0.10.1-0.60.60.9
Bone: cortical area0.20.31.01.00.2-0.7-0.1-0.60.60.4-0.60.50.20.60.2-0.50.0-0.6-0.3-0.50.60.10.10.7
Bone: cortical porosity0.60.72.6-0.4-1.00.90.90.3-0.50.4-0.10.31.60.11.11.31.11.0-0.60.7-1.00.2-0.1-1.1
Bone: cortical porosity0.40.41.8-0.2-0.90.71.2-0.1-0.20.10.3-0.01.3-0.20.60.81.30.5-0.10.1-0.5-0.30.5-0.5
Bone: cortical thickness0.50.82.5-0.8-1.60.91.21.2-0.91.3-0.10.11.30.21.60.5-0.40.7-0.90.7-0.60.2-0.20.2
Bone: cortical thickness3.44.211.70.2-0.4-0.4-1.41.7-0.80.6-2.82.70.62.82.60.7-3.41.3-2.72.6-1.13.3-3.0-1.5
Bone: cortical tissue density0.50.82.0-1.4-0.70.71.01.0-0.6-0.71.1-1.2-1.0-1.2-0.2-1.0-1.4-0.21.0-0.20.3-0.80.81.1
Condit. Reinf. active minus inactive responses2.42.810.1-1.5-1.61.33.20.5-0.0-0.82.3-2.0-0.2-1.9-0.1-1.4-0.1-0.71.9-1.40.8-2.32.72.5
Condit. Reinf. active-inactive response ratio0.80.95.5-1.2-1.71.22.30.9-0.2-0.10.9-0.70.7-0.50.9-0.4-0.50.00.4-0.10.1-0.81.31.1
Condit. Reinf. active responses1.82.35.9-1.0-0.90.72.30.00.3-1.32.0-2.0-0.8-1.9-0.7-1.6-0.1-0.82.0-1.50.8-2.22.42.2
Condit. Reinf. inactive responses1.31.73.71.21.6-1.4-0.9-1.71.3-1.70.4-0.6-1.9-0.7-1.9-1.60.1-1.31.4-1.71.2-0.90.91.1
Incentive salience index mean2.53.28.5-0.5-0.30.32.1-0.60.6-1.42.2-2.2-1.3-2.0-1.4-2.10.3-1.32.5-2.31.3-2.52.92.7
Condit. Reinf. lever presses2.13.26.40.41.0-0.70.6-1.61.2-1.71.7-1.9-2.1-1.6-2.3-2.20.7-1.72.5-2.51.6-2.22.42.2
Condit. Reinf. active minus inactive responses0.30.41.10.60.4-0.20.3-0.70.20.30.5-0.8-0.2-0.6-0.6-0.51.1-0.40.6-1.00.4-1.00.80.9
Condit. Reinf. active-inactive response ratio0.10.21.00.1-0.20.30.3-0.0-0.30.60.1-0.10.7-0.20.20.61.00.4-0.20.1-0.4-0.20.1-0.4
Condit. Reinf. active responses0.10.10.60.80.4-0.4-0.3-0.4-0.10.7-0.2-0.20.10.2-0.1-0.20.5-0.1-0.1-0.40.1-0.20.00.4
Condit. Reinf. inactive responses0.30.51.10.3-0.0-0.1-0.60.3-0.61.0-0.90.50.61.00.80.6-0.30.8-1.00.7-0.81.0-1.0-0.6
Condit. Reinf. lever presses0.10.10.5-0.2-0.10.30.10.3-0.50.50.3-0.70.0-0.40.00.20.20.20.10.1-0.3-0.20.0-0.1
Condit. Reinf. lever reinforcers received0.00.10.30.60.3-0.2-0.2-0.3-0.20.4-0.1-0.40.00.0-0.1-0.10.50.10.0-0.3-0.1-0.20.00.1
Conditioned reinforcement - actives0.00.00.10.40.2-0.1-0.2-0.20.20.2-0.20.20.10.20.00.10.4-0.2-0.2-0.10.20.1-0.1-0.1
Conditioned reinforcement - inactives0.00.10.6-0.20.10.40.4-0.10.00.10.4-0.40.2-0.40.00.00.8-0.00.3-0.4-0.0-0.50.4-0.0
Conditioned locomotion0.10.20.4-0.2-0.00.20.20.2-0.30.60.7-0.6-0.2-0.7-0.3-0.30.2-0.30.3-0.50.3-0.70.30.6
Patch foraging indifference point 0 sec0.30.72.2-0.1-0.50.31.4-0.4-0.10.10.8-1.40.2-1.0-0.6-0.61.1-0.10.8-0.90.1-1.21.51.3
Patch foraging indifference point AUC0.51.24.21.81.7-1.8-2.0-1.31.2-0.2-1.31.1-0.81.1-0.5-0.3-0.1-0.8-0.4-0.30.80.7-0.9-0.2
Delay disc. indifference point, 0s delay0.70.82.41.10.9-1.1-1.0-1.10.7-0.40.4-0.4-1.3-0.3-1.5-0.80.6-1.10.7-1.11.0-0.60.30.8
Delay disc. indifference point, 16s delay0.40.61.5-0.8-1.20.80.31.2-0.80.9-0.20.20.80.21.10.9-0.20.5-0.81.0-0.50.5-0.8-0.9
Delay disc. indifference point, 2s delay0.50.51.9-1.1-0.81.01.10.6-0.7-1.40.9-0.9-0.1-0.9-0.10.1-0.30.00.80.2-0.0-0.50.6-0.3
Delay disc. indifference point, 24s delay0.30.52.3-0.9-1.10.81.50.3-0.00.00.7-0.70.3-0.80.20.30.8-0.10.4-0.10.1-0.90.90.4
Delay disc. indifference point, 4s delay1.21.25.70.30.8-0.5-0.3-0.60.3-2.40.9-0.9-1.9-0.9-1.7-1.4-0.8-1.11.6-0.91.0-0.80.80.6
Delay disc. indifference point, 8s delay0.40.61.6-1.0-1.00.40.90.4-0.5-0.61.2-1.3-0.8-1.2-0.5-0.5-0.10.10.9-0.4-0.1-1.10.90.8
Indifference point function ln k0.82.37.1-1.9-2.12.02.71.3-1.60.22.3-2.20.3-2.2-0.1-0.10.80.61.3-0.4-0.6-1.81.81.0
Indifference point function log k0.82.37.1-1.9-2.12.02.71.3-1.60.22.3-2.20.3-2.2-0.1-0.10.80.61.3-0.4-0.6-1.81.81.0
Patch foraging total patch changes 0 sec0.20.72.3-0.5-0.80.71.5-0.0-0.50.50.8-1.40.6-1.0-0.2-0.11.10.40.5-0.5-0.4-1.11.31.0
Patch foraging total patch changes 12 sec0.91.23.21.31.3-1.6-0.5-1.51.6-0.5-0.70.2-1.00.5-0.8-1.6-0.5-1.30.3-1.21.4-0.30.61.8
Patch foraging total patch changes 18 sec0.92.16.82.62.3-2.4-1.8-2.11.7-0.9-1.20.5-1.40.9-1.1-1.6-0.7-1.30.2-1.31.30.2-0.11.2
Patch foraging total patch changes 24 sec0.41.53.31.51.6-1.5-0.6-1.81.6-0.9-0.20.1-1.30.1-1.4-1.70.4-1.40.9-1.71.4-0.60.91.5
Patch foraging total patch changes 6 sec0.20.31.01.00.8-1.0-0.8-0.80.5-0.5-0.70.3-0.40.7-0.4-0.5-0.4-0.3-0.1-0.20.30.4-0.20.2
Patch foraging time to switch 0 sec0.10.31.00.40.4-0.5-0.4-0.20.6-0.6-0.70.7-0.20.70.2-0.4-1.0-0.5-0.30.00.50.6-0.30.0
Patch foraging water rate 0 sec0.10.41.50.2-0.30.3-0.10.1-0.71.2-0.2-0.10.80.10.40.81.20.9-0.50.4-0.90.0-0.3-0.4
Patch foraging water rate 12 sec0.31.13.7-1.0-0.51.00.90.8-1.2-0.51.8-1.9-0.8-1.8-0.7-0.6-0.40.41.4-0.5-0.4-1.41.00.7
Patch foraging water rate 18 sec1.32.86.9-0.40.40.31.1-0.5-0.2-1.42.4-2.3-1.7-2.3-2.1-1.80.8-0.92.6-2.10.9-2.52.31.8
Patch foraging water rate 24 sec1.11.64.2-1.0-0.70.91.50.3-0.5-0.52.0-2.0-0.8-1.9-1.1-1.10.4-0.51.7-1.10.4-1.91.81.4
Patch foraging water rate 6 sec1.62.47.22.72.4-2.4-2.3-1.81.6-0.8-1.11.3-1.71.2-1.3-1.5-0.8-1.50.1-1.21.50.5-0.50.8
Seeking ratio, delayed vs. immediate footshock0.91.24.1-1.6-1.71.30.91.9-1.70.30.9-0.6-0.0-0.60.8-0.1-2.01.3-0.11.0-1.20.4-0.3-0.2
Distance traveled before self-admin0.30.71.9-1.0-1.01.41.10.7-1.0-0.60.6-0.60.9-0.60.60.60.70.90.30.5-0.9-0.20.2-1.2
Distance traveled after self-admin0.30.51.4-1.1-0.51.20.70.8-0.9-0.20.6-0.50.8-0.60.70.30.40.80.20.2-0.8-0.2-0.0-1.1
Extensor digitorum longus weight0.31.33.10.1-0.70.30.00.5-0.31.7-1.21.31.81.31.71.30.21.1-1.71.2-1.11.2-1.1-1.0
Bone: elastic displacement0.60.82.0-0.9-0.90.91.40.5-0.80.91.3-1.30.3-1.40.0-0.10.80.10.6-0.6-0.0-1.41.10.9
Bone: elastic work1.01.34.1-1.2-1.71.51.41.4-1.72.00.7-0.81.5-0.81.30.90.71.2-0.50.6-1.2-0.50.10.0
Bone: endosteal estimation0.51.13.01.71.1-1.4-1.6-0.81.00.6-1.71.7-0.01.60.3-0.2-0.4-0.4-1.20.10.41.2-1.1-0.1
Bone: endosteal perimeter0.61.54.12.01.3-1.6-0.5-2.01.9-0.5-0.60.7-0.50.7-0.8-1.20.7-1.70.3-1.61.6-0.40.71.3
Epididymis fat weight0.00.20.60.10.1-0.20.6-0.50.60.20.1-0.30.3-0.2-0.0-0.10.7-0.50.1-0.60.5-0.70.70.8
Delta time in closed arm before/after self-admin0.60.62.0-1.1-1.10.91.40.6-0.7-0.50.9-0.9-0.1-0.80.2-0.1-0.00.90.6-0.0-0.9-0.60.80.2
Delta time in open arm before/after self-admin1.92.35.42.31.6-2.1-2.2-1.41.71.3-2.32.10.02.20.10.10.0-1.2-1.60.11.21.5-1.40.1
Diff in mean of infusions in LGA sessions0.20.30.80.90.6-0.8-0.8-0.50.6-0.3-0.90.6-0.20.9-0.00.2-0.7-0.3-0.40.20.40.8-0.5-0.1
Delay discount exponential model param0.40.52.00.70.4-0.3-0.7-0.10.21.4-0.91.00.91.00.70.70.50.4-1.10.4-0.40.8-0.8-0.5
Extinction: sum of active levers before priming1.21.74.4-2.0-2.11.71.61.9-1.90.71.8-2.0-0.2-1.80.1-0.2-0.90.70.70.3-0.7-1.00.70.7
Active lever presses in extinction session 61.71.74.7-1.1-0.41.01.60.1-0.4-1.02.0-2.1-0.6-2.2-0.9-0.81.1-0.51.8-1.20.5-2.11.81.0
Bone: final force0.30.51.21.00.3-0.7-0.8-0.40.20.7-1.11.00.61.10.50.40.30.4-1.00.3-0.40.8-0.8-0.5
Bone: final moment0.20.40.90.90.2-0.5-0.6-0.30.10.8-0.90.90.61.00.60.30.20.4-1.00.2-0.30.7-0.7-0.3
Food consumed during 24 hour testing period2.75.413.73.53.2-3.6-3.7-2.32.8-0.8-2.92.9-1.82.7-0.9-1.5-1.9-2.0-1.1-0.62.11.9-1.70.4
Glucose0.30.52.10.5-0.20.1-0.1-0.2-0.11.4-0.50.41.30.40.51.11.50.5-0.90.4-0.50.3-0.5-0.6
Heart weight0.71.13.8-1.8-1.31.01.11.5-1.2-1.21.0-1.1-0.7-1.10.2-0.6-1.90.70.80.4-0.7-0.40.40.3
Delay discount hyperbolic model param0.50.72.60.70.4-0.2-0.7-0.10.11.6-1.01.11.11.10.80.90.70.5-1.20.5-0.51.0-0.9-0.7
Intermittent access intake day 1-15 change0.42.35.01.72.2-1.9-1.0-2.02.2-1.6-0.20.2-1.70.2-1.5-1.8-0.6-2.21.0-1.82.1-0.50.71.4
Intermittent access intake escalation0.31.53.11.31.7-1.5-0.8-1.51.8-1.2-0.10.1-1.40.1-1.2-1.5-0.7-1.70.8-1.51.7-0.40.61.2
Intermittent access intake escalation 20.91.53.31.21.8-1.6-1.0-1.51.7-0.9-0.20.3-1.50.2-1.3-1.6-0.6-1.80.7-1.51.7-0.40.51.3
Intermitt. access day 1 inactive lever presses0.11.24.10.60.5-0.10.4-0.90.3-0.31.2-1.2-1.0-1.2-1.4-0.92.0-0.81.4-1.40.7-1.51.41.1
Intermitt. access day 15 inactive lever presses0.10.61.9-0.4-0.60.90.40.8-0.81.4-0.10.21.10.10.91.21.00.7-0.70.7-0.70.2-0.5-0.8
Intermitt. access escalation Index0.20.61.7-0.8-0.70.70.80.8-0.90.21.3-1.3-0.5-1.3-0.4-0.4-0.40.00.8-0.20.0-1.00.70.8
Intermittent access day 1 total infusions0.72.04.6-1.5-1.91.70.91.8-2.02.10.3-0.41.6-0.31.41.70.81.9-1.01.5-1.90.3-0.6-1.1
Intermittent access day 15 total infusions0.10.30.8-0.8-0.70.90.70.7-0.70.50.5-0.60.4-0.50.40.40.30.60.10.2-0.6-0.30.2-0.2
Intermittent access terminal intake (last 3 days)0.20.41.2-0.9-0.71.00.70.6-0.70.80.5-0.50.7-0.50.40.61.10.6-0.00.2-0.7-0.30.2-0.4
Intermittent access total infusions0.60.71.8-0.9-1.01.10.61.0-1.11.40.2-0.31.1-0.20.91.00.91.1-0.50.7-1.10.1-0.3-0.7
Intermittent access day 1 locomotion0.71.34.9-1.3-1.71.50.81.8-1.92.21.0-0.90.8-1.00.70.90.21.2-0.40.8-1.2-0.4-0.2-0.0
Intermittent access day 15 total locomotion0.31.14.0-0.9-1.11.00.31.3-1.22.0-0.20.31.40.21.31.30.41.1-1.21.2-1.10.6-0.9-0.9
Intermittent access total locomotion1.61.97.0-1.0-1.51.30.31.8-1.62.6-0.30.31.70.31.61.60.21.5-1.51.6-1.50.8-1.2-1.1
Intermittent access standard deviation0.20.92.00.61.3-0.8-0.1-1.31.2-1.30.3-0.4-1.0-0.3-1.1-1.00.3-1.31.0-1.41.3-0.80.90.9
Left kidney weight0.42.97.42.12.2-2.4-0.9-2.52.7-2.2-1.20.8-1.61.0-1.1-2.2-0.9-2.00.6-1.82.0-0.10.71.7
Right kidney weight0.32.36.32.21.7-2.2-0.7-2.12.5-0.9-1.71.5-0.71.7-0.3-1.5-0.7-1.8-0.3-1.21.90.60.21.5
Cocaine induced anxiety0.30.92.3-1.1-0.70.91.20.3-0.7-0.41.5-1.5-0.3-1.5-0.6-0.51.10.21.2-0.5-0.2-1.31.20.5
Post-drug Anxiety0.20.30.7-0.8-0.60.80.80.5-0.7-0.30.6-0.60.2-0.60.2-0.00.00.50.30.1-0.5-0.40.3-0.2
Baseline Anxiety0.50.92.80.60.2-0.5-0.70.10.4-0.3-1.41.40.61.41.00.5-1.70.3-1.10.9-0.21.5-1.2-0.9
Tail length1.47.416.63.64.0-3.5-2.4-4.13.8-2.7-0.60.6-2.90.7-3.2-2.80.4-3.51.8-3.23.4-0.71.21.9
Length with tail0.73.09.62.32.4-2.3-1.3-3.03.1-1.2-0.90.9-0.80.9-1.5-1.11.4-2.40.5-2.02.3-0.30.70.9
Length without tail0.10.72.90.1-0.30.00.1-0.10.31.4-0.90.81.70.81.21.21.20.3-1.30.4-0.20.5-0.6-0.6
Times rat made contact with spout0.10.11.0-0.00.2-0.2-0.40.20.0-0.2-0.10.0-0.60.0-0.1-0.4-1.0-0.20.10.10.20.2-0.20.1
Lifetime Intake0.40.51.5-0.8-0.81.00.60.7-0.91.10.3-0.40.9-0.30.60.81.20.9-0.30.5-0.9-0.1-0.1-0.6
Liver weight, left0.40.62.41.10.8-0.7-0.2-1.31.00.20.1-0.1-0.2-0.0-0.9-0.41.5-1.10.3-1.11.0-0.70.60.7
Liver weight, right0.61.12.71.30.9-1.0-0.2-1.61.20.30.2-0.1-0.4-0.2-1.2-1.01.6-1.20.5-1.61.2-1.01.01.4
Locomotor activity1.32.04.90.60.0-0.3-1.31.0-0.81.7-1.91.71.11.71.51.1-1.41.1-2.21.7-1.02.1-2.2-1.1
Locomotor testing distance0.92.25.20.60.1-0.2-1.41.0-0.91.6-1.91.81.11.81.61.2-1.31.2-2.11.8-1.22.2-2.3-1.5
Locomotor testing rearing0.62.26.71.81.5-1.9-2.0-0.51.0-0.4-2.22.1-0.72.20.5-0.8-2.6-0.7-1.20.30.81.9-1.60.0
Locomotion in novel chamber1.21.64.10.3-0.6-0.2-0.81.1-0.61.4-1.61.40.81.51.30.6-2.00.9-1.81.5-0.81.9-1.8-0.7
Locomotion in novel chamber post-restriction0.10.41.40.91.0-0.7-1.2-0.50.01.00.2-0.1-0.6-0.1-1.0-0.70.5-0.70.1-0.70.7-0.2-0.20.6
Fecal boli incidents, locomotor time 10.51.34.71.51.7-1.3-0.4-2.21.9-1.6-0.30.4-0.50.5-1.0-0.81.1-1.30.6-1.31.3-0.40.90.6
Change in fecal boli incidents, locomotor task1.11.13.8-0.00.4-0.5-0.2-0.20.1-1.31.0-1.1-2.0-1.0-1.6-1.7-1.2-0.91.5-1.00.9-0.90.81.3
Time >=10cm from walls, locomotor time 10.40.43.10.10.7-0.3-0.7-0.10.2-1.6-0.50.5-0.50.6-0.1-0.1-1.8-0.20.10.40.20.8-0.5-0.7
Bouts of movement, locomotor time 10.30.41.3-0.7-0.20.50.7-0.0-0.2-0.61.0-1.2-0.2-1.0-0.4-0.20.7-0.11.0-0.6-0.0-1.00.90.1
Total resting periods, locomotor time 10.70.82.4-1.1-0.50.91.20.2-0.3-0.71.4-1.5-0.2-1.4-0.4-0.40.8-0.01.3-0.8-0.1-1.41.30.3
Rest time, locomotor task time 10.40.72.4-1.1-0.71.01.60.2-0.40.11.1-1.10.4-1.1-0.1-0.11.10.50.8-0.5-0.6-1.21.20.4
Distance moved, locomotor task time 10.41.12.90.4-0.1-0.2-1.20.8-0.41.5-1.21.30.61.11.01.1-0.80.4-1.61.4-0.41.4-1.7-1.0
Vertical activity count, locomotor time 10.42.66.42.01.8-2.1-2.5-1.31.6-0.9-2.52.5-0.12.40.40.2-0.9-0.4-1.40.60.42.1-1.9-1.1
Time >=10cm from walls, locomotor time 20.30.93.8-0.7-0.80.90.00.7-0.90.70.00.01.30.10.81.91.21.0-0.61.2-1.00.4-0.7-1.8
Bouts of movement, locomotor time 20.10.40.8-0.9-0.70.70.50.8-0.8-0.70.7-0.7-0.2-0.80.10.1-0.70.70.60.1-0.7-0.30.2-0.2
Total resting periods, locomotor time 20.00.20.7-0.6-0.30.40.20.5-0.5-0.80.3-0.2-0.2-0.40.10.0-0.80.50.40.1-0.6-0.00.0-0.3
Rest time, locomotor task time 20.20.30.70.20.8-0.6-0.5-0.60.7-0.8-0.40.4-0.50.6-0.3-0.7-0.8-0.40.1-0.10.30.4-0.10.0
Distance moved, locomotor task time 21.52.05.2-1.2-1.81.50.71.7-1.62.30.1-0.01.9-0.01.72.21.01.6-1.21.5-1.60.4-0.9-1.4
Vertical activity count, locomotor time 20.51.12.71.20.6-1.2-1.3-0.60.90.8-1.71.50.71.60.90.80.50.3-1.50.4-0.21.1-1.3-0.7
Light reinforcement 12.411.128.05.04.8-5.3-4.3-4.54.6-1.9-3.53.4-2.53.4-1.9-2.9-1.3-3.6-0.7-2.03.71.7-1.01.6
Light reinforcement 23.37.519.34.44.2-4.2-3.7-3.83.9-1.2-3.13.1-1.43.0-1.4-1.6-0.1-2.9-0.8-1.43.01.6-1.10.4
Bone: marrow area0.51.23.01.71.1-1.4-1.6-0.81.00.5-1.71.7-0.01.70.3-0.1-0.5-0.3-1.20.20.41.3-1.2-0.2
Bone: maximum diameter0.30.61.80.4-0.1-0.20.9-0.80.90.00.5-0.50.1-0.5-0.3-0.70.9-1.00.7-1.21.0-1.11.31.3
Bone: maximum force0.20.41.50.70.0-0.3-0.5-0.30.11.2-0.70.70.90.70.50.60.70.3-0.90.2-0.30.5-0.6-0.4
Bone: maximum moment0.20.31.60.6-0.1-0.3-0.3-0.20.01.3-0.60.60.80.60.60.50.60.2-0.90.1-0.20.3-0.5-0.1
Mean time between licks in bursts0.10.62.60.2-0.0-0.30.50.00.5-0.40.4-0.6-0.8-0.4-0.3-1.4-1.1-1.00.5-0.81.1-0.70.71.6
Mean num. licks in bursts0.10.41.1-0.7-0.40.80.40.3-0.7-0.21.0-0.9-0.1-0.9-0.50.41.10.40.7-0.0-0.5-0.60.4-0.6
Cd content in liver1.51.65.4-2.2-2.31.72.32.0-1.20.70.4-0.51.2-0.41.90.2-1.20.9-0.50.9-0.7-0.10.30.6
Co content in liver2.93.410.6-2.8-2.42.53.31.8-1.90.82.5-2.60.9-2.60.40.20.71.01.2-0.2-0.9-2.11.91.1
Cu content in liver0.30.41.1-0.5-0.80.61.00.7-0.60.8-0.0-0.40.9-0.30.90.2-0.10.9-0.40.3-0.8-0.20.20.4
Fe content in liver1.51.85.7-0.00.70.10.3-1.30.3-0.61.9-2.1-0.6-2.1-2.0-0.22.4-0.51.9-1.50.4-2.11.70.3
K content in liver0.90.94.7-0.6-0.91.00.61.0-1.52.20.7-1.01.0-1.10.40.91.01.0-0.30.3-1.0-0.7-0.0-0.0
Mg content in liver0.80.93.4-0.4-0.70.80.80.5-1.41.91.1-1.50.6-1.4-0.10.41.40.80.3-0.4-0.8-1.30.60.6
Mn content in liver0.30.31.51.00.5-0.70.0-0.60.60.1-0.40.2-0.30.40.0-0.9-0.3-0.4-0.1-0.70.4-0.10.31.2
Na content in liver0.10.20.80.50.6-0.3-0.9-0.40.00.4-0.10.1-0.0-0.0-0.40.40.80.1-0.1-0.0-0.20.1-0.4-0.6
Rb content in liver0.10.20.50.60.5-0.5-0.2-0.40.3-0.0-0.1-0.3-0.4-0.3-0.4-0.6-0.1-0.40.2-0.50.4-0.30.20.7
Se content in liver1.61.98.50.70.8-0.30.6-1.80.7-0.01.4-1.6-0.1-1.5-1.7-0.32.9-0.71.5-1.90.5-2.11.90.8
Sr content in liver0.60.51.6-0.8-1.10.91.11.0-1.01.30.3-0.30.90.10.80.60.20.9-0.50.5-0.80.10.10.3
Zn content in liver0.81.02.2-1.2-1.51.41.41.2-1.50.90.5-0.51.2-0.51.10.80.21.4-0.30.7-1.4-0.20.2-0.2
Bone: minimum diameter0.91.75.72.41.7-2.0-1.6-1.81.9-0.5-1.31.4-0.81.3-0.7-1.0-0.2-1.6-0.3-0.91.60.5-0.40.6
Time in familiar zone, hab. session 10.80.93.60.10.5-0.60.1-0.51.0-1.90.2-0.2-1.3-0.2-0.7-1.4-1.3-1.30.9-0.81.3-0.40.71.1
Time in novel zone, hab. session 11.01.12.8-0.8-0.81.1-0.21.3-1.71.30.20.00.80.00.71.50.41.6-0.71.3-1.60.6-1.0-1.6
Total zone transitions, hab. session 10.50.72.11.00.9-1.0-1.5-0.30.40.2-1.31.0-0.21.10.30.1-0.80.0-0.90.4-0.01.2-1.2-0.6
Total locomotion distance, hab. session 10.40.51.60.80.6-0.6-1.30.1-0.11.0-1.00.7-0.01.00.30.2-0.50.3-1.00.5-0.31.1-1.2-0.5
Locomotion velocity, hab. session 10.50.72.01.10.8-0.9-1.4-0.20.11.2-1.20.90.01.10.30.1-0.40.3-1.10.3-0.31.1-1.2-0.3
Time in familiar zone, hab. session 20.80.91.91.11.2-1.4-0.8-1.11.3-0.9-0.40.2-1.20.4-0.9-1.4-0.7-1.30.3-1.11.3-0.10.31.2
Time in novel zone, hab. session 22.12.34.5-1.5-1.91.80.92.1-1.81.6-0.10.51.80.22.01.9-0.21.8-1.22.0-1.80.9-1.0-1.6
Total zone transitions, hab. session 20.60.72.31.11.2-1.4-1.1-0.60.5-0.2-0.90.1-1.20.3-0.4-1.3-1.5-0.6-0.1-0.60.60.3-0.41.1
Total locomotion distance, hab. session 20.40.51.51.20.8-1.0-1.1-0.40.31.0-1.20.8-0.10.90.3-0.3-0.60.1-0.9-0.0-0.00.7-0.90.4
Locomotion velocity, hab. session 20.40.61.71.30.9-1.1-1.2-0.50.30.9-1.30.8-0.00.90.3-0.2-0.40.2-1.0-0.0-0.10.8-0.90.2
Novel to familiar place preference ratio0.60.81.9-0.8-0.70.6-0.21.4-1.00.8-0.40.90.50.61.10.7-1.10.7-1.01.3-0.71.0-1.2-0.9
Novelty place preference0.91.12.4-0.6-0.60.5-0.51.4-0.90.9-0.71.30.60.91.30.9-1.20.8-1.31.5-0.71.4-1.5-1.2
Time in novel zone, NPP test0.91.12.7-0.9-0.80.9-0.31.6-1.30.9-0.41.00.60.61.21.1-0.91.0-1.11.6-1.01.1-1.4-1.3
Total zone transitions, NPP test0.50.72.21.41.1-1.5-0.8-1.21.10.2-1.00.2-0.40.4-0.2-1.0-0.4-0.7-0.3-0.80.80.1-0.01.1
Total locomotion distance, NPP test0.10.20.60.70.4-0.6-0.5-0.20.20.8-0.60.0-0.20.20.2-0.5-0.50.0-0.4-0.20.00.1-0.30.6
Locomotion velocity, NPP test0.20.30.91.00.5-0.8-0.3-0.60.70.9-0.80.20.10.50.3-0.5-0.1-0.2-0.6-0.40.30.1-0.10.8
Intraocular pressure1.22.05.6-2.4-2.32.22.21.8-1.80.51.5-1.50.9-1.40.90.70.31.40.40.8-1.4-0.80.7-0.2
Delta distance traveled before/after self-admin0.10.10.50.20.4-0.5-0.6-0.0-0.10.7-0.10.2-0.40.1-0.2-0.3-0.20.2-0.2-0.3-0.20.1-0.30.4
Delta ambulatory time before/after self-admin0.40.61.40.91.2-1.1-0.9-0.60.70.1-0.00.1-1.20.0-0.8-1.2-0.7-0.90.3-1.10.9-0.30.01.1
Parametrial fat weight0.20.61.51.20.7-1.0-0.5-1.01.20.5-1.01.00.41.20.30.00.6-0.7-0.7-0.40.70.5-0.30.2
Pavlov. Cond. lever latency0.50.72.90.20.1-0.4-0.80.5-0.0-0.2-1.21.5-0.01.10.70.1-1.70.3-1.00.9-0.21.2-1.2-0.4
Pavlov. Cond. magazine entry latency0.50.61.9-1.1-0.61.00.90.5-0.80.21.4-1.30.0-1.1-0.50.31.00.40.8-0.2-0.4-0.80.8-0.0
Pavlov. Cond. change in total contacts1.01.12.40.30.4-0.20.5-1.00.5-0.31.3-1.3-0.7-1.1-1.5-0.81.5-1.01.4-1.60.9-1.41.51.1
Pavlov. Cond. index score0.81.02.9-0.9-0.61.01.30.2-0.60.51.7-1.70.1-1.4-0.70.11.60.01.1-0.7-0.1-1.31.30.5
Pavlov. Cond. latency score0.50.62.1-0.6-0.40.71.0-0.1-0.20.41.3-1.40.1-1.1-0.6-0.01.4-0.10.9-0.70.1-1.11.20.5
Pavlov. Cond. lever contacts0.70.83.4-0.6-0.40.80.9-0.1-0.50.51.4-1.70.2-1.3-0.70.31.90.11.0-0.7-0.2-1.21.20.2
Pavlov. Cond. magazine entry number1.21.53.61.61.2-1.7-1.5-0.81.4-0.8-1.91.8-0.61.60.3-0.8-1.8-0.8-0.90.10.91.2-1.10.2
Pavlov. Cond. intertrial magazine entries1.11.43.8-0.1-0.30.11.5-1.00.5-0.61.2-1.4-0.0-1.5-0.8-0.81.4-0.81.3-1.60.7-1.92.01.6
Pavlov. Cond. lever-magazine prob. diff.1.01.23.7-1.2-0.91.31.50.4-0.80.91.7-1.80.5-1.5-0.40.51.90.30.9-0.5-0.3-1.31.30.2
Pavlov. Cond. response bias1.21.44.3-1.3-0.71.31.30.4-1.10.22.1-2.1-0.0-1.8-0.90.31.80.51.4-0.6-0.6-1.51.40.1
Pavlov. Cond. lever latency0.10.20.8-0.4-0.70.50.50.30.00.1-0.00.60.90.30.60.70.40.2-0.40.5-0.20.2-0.1-0.4
Pavlov. Cond. magazine entry latency0.10.10.40.10.1-0.10.2-0.20.4-0.2-0.1-0.2-0.3-0.2-0.0-0.5-0.3-0.60.2-0.30.6-0.20.30.4
Pavlov. Cond. change in total contacts0.20.51.8-0.10.30.10.2-0.2-0.3-0.60.8-1.3-0.9-1.0-0.9-0.70.0-0.21.1-0.70.1-0.90.80.7
Pavlov. Cond. index score0.20.20.80.20.4-0.2-0.1-0.3-0.0-0.30.3-0.9-0.8-0.7-0.7-0.6-0.1-0.40.7-0.50.3-0.50.40.5
Pavlov. Cond. latency score0.20.30.80.30.5-0.3-0.2-0.40.1-0.30.3-0.8-0.9-0.7-0.7-0.70.0-0.60.7-0.60.5-0.60.50.5
Pavlov. Cond. lever contacts0.10.20.80.50.7-0.6-0.6-0.30.1-0.3-0.2-0.4-0.9-0.1-0.4-0.7-0.7-0.20.2-0.30.20.0-0.10.3
Pavlov. Cond. magazine entry number0.10.10.4-0.2-0.20.1-0.20.3-0.10.0-0.20.70.20.50.30.3-0.30.3-0.40.4-0.20.4-0.5-0.3
Pavlov. Cond. intertrial magazine entries0.71.53.61.81.7-1.9-1.3-1.61.5-1.3-0.91.0-1.21.0-1.0-1.4-0.6-1.40.2-1.11.40.3-0.00.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.00.3-0.10.0-0.1-0.1-0.20.4-0.9-0.7-0.8-0.6-0.6-0.1-0.30.6-0.50.2-0.60.40.5
Pavlov. Cond. response bias0.00.10.40.20.3-0.2-0.2-0.1-0.20.1-0.1-0.6-0.4-0.3-0.2-0.3-0.20.10.2-0.2-0.1-0.10.00.2
Time in closed arm before self-admin0.71.22.70.91.4-0.9-0.9-1.00.7-1.10.6-0.4-1.4-0.6-1.6-1.5-0.6-1.71.2-1.21.7-0.70.60.9
Time in closed arm after self-admin0.60.74.2-0.10.1-0.10.5-0.60.3-2.00.9-0.6-1.0-0.8-1.0-0.9-0.5-0.31.3-0.60.3-0.81.10.6
Time in open arm before self-admin0.50.62.2-1.5-1.21.11.40.9-0.8-0.60.7-0.80.3-0.70.70.30.01.00.30.2-1.0-0.40.5-0.3
Time in open arm after self-admin0.40.52.7-0.1-0.40.2-0.10.5-0.31.6-0.60.50.80.60.90.90.50.3-1.10.7-0.30.6-0.7-0.4
Bone: periosteal estimation0.51.13.81.91.1-1.6-1.3-1.11.30.3-1.61.5-0.21.60.2-0.6-0.5-0.8-0.9-0.30.80.9-0.70.4
Bone: periosteal perimeter0.61.13.21.40.6-1.20.2-1.41.6-0.3-0.30.4-0.40.4-0.4-1.40.1-1.70.3-1.51.7-0.60.91.8
Bone: post-yield work0.50.82.41.20.9-1.0-1.5-0.60.7-0.3-1.31.4-0.11.3-0.00.3-0.3-0.3-0.80.40.31.2-1.2-0.9
Progressive ratio test 1 active lever presses0.61.12.9-1.0-1.21.20.51.1-1.31.70.0-0.01.3-0.01.11.41.11.4-0.91.1-1.40.3-0.6-0.9
Progressive ratio test 1 breakpoint0.71.22.9-1.0-1.31.30.61.2-1.31.70.0-0.11.4-0.01.11.51.11.4-0.91.1-1.40.3-0.5-1.0
Progressive ratio test 1 inactive lever presses0.20.65.4-0.4-0.61.00.60.3-0.71.10.5-0.40.8-0.50.30.92.30.7-0.10.2-0.7-0.40.2-0.6
Progressive ratio test 2 active lever presses0.60.81.6-1.0-1.11.10.61.0-0.90.9-0.10.11.20.11.11.30.51.3-0.71.0-1.30.4-0.5-1.1
Progressive ratio test 2 breakpoint0.70.91.8-1.1-1.11.10.61.0-1.00.8-0.10.11.20.11.21.30.51.3-0.71.0-1.30.4-0.5-1.1
Progressive ratio test 2 inactive lever presses0.41.32.8-1.4-1.51.71.11.5-1.41.20.3-0.31.3-0.31.31.30.71.6-0.51.1-1.60.1-0.3-1.1
Incentive Sensitization - Responses0.10.10.4-0.5-0.30.30.30.20.0-0.4-0.30.30.40.30.50.5-0.30.5-0.20.4-0.50.4-0.2-0.6
Incentive Sensitization - Breakpoint0.10.10.3-0.4-0.20.20.20.10.1-0.5-0.30.30.30.30.50.4-0.40.4-0.20.3-0.40.4-0.2-0.5
Sum of active levers in priming session hrs 5-60.50.41.20.1-0.2-0.3-0.70.5-0.30.9-0.80.60.30.70.60.4-1.10.5-1.00.7-0.40.9-1.0-0.2
Progressive ratio0.30.93.30.90.8-1.1-1.0-0.61.1-0.6-1.81.4-0.21.40.4-0.2-1.8-0.4-0.80.50.41.3-0.8-0.1
Food seeking constrained by brief footshock1.21.53.51.91.8-1.6-0.8-1.81.9-0.9-0.60.3-1.00.4-1.1-1.30.1-1.70.6-1.31.7-0.40.71.3
Seeking ratio, punishment vs. effort0.30.74.20.80.8-0.40.0-1.00.60.00.7-0.5-0.2-0.5-0.9-0.52.1-0.90.7-1.30.9-1.10.90.7
Retroperitoneal fat weight0.20.72.11.00.3-0.90.1-0.81.01.4-1.30.81.01.20.80.10.7-0.5-1.1-0.40.60.3-0.10.8
Reaction time number correct0.31.23.2-1.4-1.31.41.80.8-1.00.01.7-1.50.1-1.7-0.2-0.10.60.11.2-0.3-0.2-1.41.40.6
Reaction time mean minus median0.10.72.3-1.1-1.21.41.30.7-0.50.80.7-0.41.2-0.40.81.11.50.4-0.10.3-0.4-0.40.4-0.8
Reaction time mean minus median AUC0.21.43.4-1.6-1.71.91.71.1-0.91.50.8-0.71.7-0.61.11.41.70.8-0.30.6-0.8-0.50.4-0.8
Reaction time num false alarms0.71.14.0-1.6-2.01.42.01.5-1.00.50.3-0.41.2-0.21.50.4-0.81.1-0.50.9-1.00.00.30.2
Reaction time num false alarms AUC0.51.03.8-1.8-1.81.42.01.5-1.1-0.00.7-0.80.6-0.70.90.1-0.80.90.10.5-0.8-0.40.60.4
Reaction time trials correct on left0.31.23.2-1.4-1.31.41.80.8-1.00.01.7-1.50.1-1.7-0.2-0.10.60.11.2-0.3-0.2-1.41.40.6
Reaction time trials on left0.31.13.4-1.4-1.41.51.80.9-1.00.11.6-1.50.2-1.7-0.10.00.60.21.0-0.2-0.2-1.31.30.5
Reaction time mean1.32.97.4-2.4-2.72.62.12.2-1.71.70.9-0.72.2-0.72.12.01.11.6-0.81.5-1.6-0.1-0.1-1.4
Reaction time mean AUC1.22.86.9-2.4-2.62.52.02.2-1.71.80.9-0.62.2-0.61.92.01.11.6-0.81.5-1.6-0.1-0.2-1.3
Median of all reaction times1.93.07.7-2.5-2.82.62.12.3-1.91.71.0-0.82.1-0.82.01.90.81.8-0.81.6-1.7-0.1-0.2-1.3
Reaction time omissions1.01.74.6-1.7-1.81.51.31.4-0.60.4-0.50.52.20.72.11.7-0.21.1-1.21.6-1.11.0-0.6-1.5
Reaction time false alarm rate0.20.30.8-0.8-0.90.50.90.7-0.50.00.0-0.10.40.10.70.0-0.80.7-0.30.4-0.60.10.00.2
Reaction time premature initiation rate3.14.810.33.22.9-3.1-2.1-3.02.9-1.3-0.70.8-2.50.7-2.5-2.6-0.3-2.81.1-2.52.7-0.50.72.2
Reaction time premature initiations1.03.15.72.22.0-2.1-1.1-2.22.2-1.20.00.1-2.2-0.0-2.2-2.3-0.1-2.41.4-2.22.3-1.01.12.1
Std. dev. reaction times0.31.02.5-1.4-1.51.61.31.0-0.50.80.5-0.21.5-0.21.21.41.20.5-0.40.8-0.5-0.10.0-1.2
Reaction time trials completed0.31.13.4-1.4-1.41.51.80.9-1.00.11.6-1.50.2-1.7-0.10.00.60.21.0-0.2-0.2-1.31.30.5
Reaction time trials AUC0.31.13.3-1.5-1.41.61.81.0-1.10.21.5-1.40.3-1.60.10.10.50.40.9-0.0-0.4-1.21.10.4
Run reversals in cocaine runway, females2.52.86.3-0.4-1.00.60.10.8-0.72.4-1.61.42.41.52.22.51.31.9-2.32.0-1.91.6-1.6-1.7
Run reversals in cocaine runway, males0.50.63.1-1.0-0.30.90.40.8-0.7-1.4-0.00.10.60.10.80.4-1.70.7-0.00.8-0.70.6-0.3-1.1
Latency to leave start box in cocaine runway1.21.63.5-0.4-0.60.3-0.20.8-0.31.3-1.31.41.81.41.91.60.21.1-1.91.5-1.11.6-1.5-1.5
Latency to leave start box in cocaine runway, F1.31.73.3-0.6-0.90.9-0.11.1-1.21.7-0.70.81.80.91.61.70.71.5-1.61.7-1.51.3-1.4-1.7
Latency to leave start box in cocaine runway, M0.50.51.60.60.5-0.9-0.5-0.51.20.1-1.21.30.31.30.60.2-0.3-0.4-0.90.00.40.8-0.60.0
Std. dev. time between licks in bursts0.61.12.41.41.1-1.4-0.7-0.91.4-1.1-0.60.6-1.20.6-0.6-1.5-1.4-1.40.3-0.91.40.10.21.3
Total sessions with >9 infusions1.62.04.4-1.8-1.61.91.71.3-1.91.51.9-2.00.6-1.90.00.62.11.10.70.1-1.1-1.51.00.2
Short access day 1 total inactive lever presses0.50.99.20.3-0.10.5-0.0-0.2-0.21.6-0.40.41.30.40.61.33.00.6-0.80.4-0.60.2-0.3-1.1
Short access day 10 total inactive lever presses0.21.63.21.31.4-1.2-0.7-1.41.0-0.40.6-0.6-1.7-0.6-1.8-1.50.6-1.71.1-1.71.7-1.21.01.7
Short access day 1 total infusions1.73.314.0-2.2-1.92.52.31.1-1.91.12.3-2.31.0-2.30.10.93.71.41.00.1-1.5-1.91.5-0.3
Short access day 10 total infusions0.30.63.1-0.7-0.80.90.40.9-1.21.80.6-0.60.7-0.60.40.51.00.8-0.30.3-0.7-0.4-0.1-0.1
Short access total infusions0.71.03.3-1.2-1.11.51.10.9-1.31.31.0-1.00.9-1.00.50.81.81.10.10.3-1.1-0.70.4-0.4
Short access day 1 locomotion1.72.87.4-2.2-2.22.51.91.7-2.21.71.7-1.71.3-1.70.61.22.71.70.30.8-1.7-1.10.7-0.6
Short access day 10 total locomotion0.31.03.4-1.3-1.31.20.81.8-1.71.61.3-1.30.1-1.30.2-0.0-1.00.60.10.3-0.5-0.70.10.7
Short access total locomotion1.42.15.1-1.9-2.02.11.52.1-2.32.11.8-1.80.7-1.80.50.60.81.20.20.5-1.2-1.10.40.2
One hour access (0.3 mA shock)0.40.51.0-0.9-0.90.80.41.0-0.81.00.0-0.10.8-0.00.90.8-0.10.9-0.60.7-0.90.3-0.4-0.6
Compulsive drug intake1.11.74.0-0.40.10.20.9-0.3-0.1-0.91.9-2.0-1.4-1.9-1.4-1.40.2-0.81.9-1.60.7-1.91.71.6
One hour access (shock baseline)0.51.32.4-0.7-0.90.6-0.11.0-0.61.1-1.01.01.41.01.61.4-0.51.2-1.51.5-1.21.3-1.3-1.4
Social response proportion0.70.81.8-0.3-0.90.50.30.8-0.40.7-0.91.11.20.91.31.0-0.71.0-1.21.3-0.91.1-0.8-0.7
Social responses0.50.77.70.3-0.2-0.4-0.20.7-0.1-0.0-1.01.0-0.10.80.8-0.5-2.80.1-0.80.70.01.0-0.80.5
Social time0.60.92.50.60.8-0.40.2-0.60.5-1.50.7-0.2-1.5-0.5-1.2-1.6-0.7-1.01.3-1.30.9-0.81.01.2
Soleus weight0.10.31.0-0.1-0.30.0-0.10.5-0.30.0-0.70.80.30.70.90.2-1.00.5-0.60.7-0.50.8-0.6-0.4
Bone: stiffness0.81.53.01.30.4-0.7-1.4-0.50.41.2-1.71.61.21.70.81.30.60.6-1.71.0-0.61.5-1.6-1.5
Tibialis anterior weight0.10.52.4-0.9-0.90.91.50.4-0.20.20.8-0.90.5-0.80.4-0.10.3-0.00.6-0.30.0-0.81.10.7
Time to tail flick, vehicle, before self-admin0.30.31.40.50.7-0.7-0.9-0.60.6-1.2-0.60.5-0.30.5-0.30.0-0.9-0.30.00.40.40.7-0.4-0.5
Time to tail flick, vehicle, after self-admin0.51.03.10.90.5-1.1-1.0-0.61.2-1.2-1.51.8-0.21.50.40.2-1.70.0-0.80.7-0.01.5-0.9-0.5
Time to tail flick, test, before self-admin1.72.05.0-1.5-1.71.81.31.4-1.31.4-0.10.22.20.01.82.11.51.5-1.11.6-1.50.5-0.5-1.6
Time to tail flick, test, after self-admin0.10.10.60.20.3-0.2-0.1-0.10.5-0.5-0.40.30.10.30.20.1-0.8-0.5-0.10.30.50.3-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.40.30.1-0.20.3-0.40.7-0.3-0.40.60.10.40.20.00.4-0.0-0.2-0.20.00.10.10.0
Delta time to tail flick, test, before/after SA0.40.51.60.20.5-0.40.2-0.20.4-1.00.5-0.5-1.0-0.4-0.6-1.1-1.3-0.80.9-0.80.8-0.60.71.1
Tibia length0.20.54.60.50.4-0.0-0.1-0.90.20.30.6-0.90.3-0.7-0.90.52.1-0.20.5-0.60.1-0.80.6-0.4
Ambulatory time before self-admin0.31.02.6-1.1-1.21.61.11.1-1.40.30.5-0.61.4-0.50.91.01.31.3-0.20.8-1.3-0.1-0.0-1.3
Ambulatory time after self-admin0.10.10.5-0.30.10.4-0.00.3-0.4-0.00.2-0.10.4-0.10.4-0.10.40.2-0.0-0.1-0.2-0.1-0.2-0.7
Bone: tissue strength0.90.92.8-1.1-1.21.21.70.5-0.50.91.2-1.11.1-1.30.40.51.40.30.3-0.2-0.3-1.21.00.3
Total heroin consumption0.20.31.2-0.1-0.3-0.0-0.10.7-0.40.9-0.60.20.30.40.70.2-1.10.3-0.80.5-0.20.5-0.60.2
Bone: trabecular number2.75.014.22.23.3-2.4-2.2-2.61.9-3.40.4-0.5-3.8-0.4-3.5-2.6-0.5-2.22.4-2.32.1-0.71.01.2
Bone: trabecular spacing2.03.07.5-2.0-2.52.01.72.2-1.52.6-0.10.12.7-0.02.72.00.31.5-1.71.8-1.40.5-0.7-1.0
Bone: trabecular thickness0.50.62.71.41.4-1.1-1.7-0.90.4-0.3-0.60.6-1.00.8-1.0-0.3-0.1-0.30.1-0.30.20.5-0.6-0.3
Bone: trabecular tissue density2.03.57.2-1.5-1.81.60.31.9-1.71.9-0.90.72.50.92.42.70.22.4-2.12.5-2.31.5-1.8-2.5
Water consumed over 24 hours0.40.72.71.11.2-1.2-1.7-0.30.4-0.0-1.00.9-1.00.8-0.3-0.6-1.4-0.2-0.40.10.20.9-1.00.1
Number of responses in last shaping day1.62.05.1-1.2-0.91.41.90.2-0.7-0.92.3-2.3-0.4-2.3-0.9-0.51.90.31.9-0.8-0.3-2.02.00.6