Hub : Genes

Brme1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Brme1 0.12 0.05 3.4e-09 0.08 0.08 0.08 0.03 2.2e-09 6.4e-09 4.5e-09 1.3e-04
2 Liver mRNA stability Brme1 0.11 0.05 1.0e-11 0.12 0.1 0.1 0.11 4.5e-13 3.1e-11 2.8e-11 2.8e-12
3 Liver gene expression Brme1 0.07 0.04 1.1e-04 0.01 0.01 0.01 0.01 2.3e-02 2.1e-02 6.0e-02 1.7e-02
4 BLA mRNA stability Brme1 0.11 0.06 1.1e-03 0.07 0.06 0.04 0.06 2.0e-04 6.9e-04 5.0e-03 3.3e-04
5 NAcc gene expression Brme1 0.03 0.02 5.9e-03 0.03 0.02 0.03 0.02 1.6e-04 4.6e-03 3.0e-04 7.2e-04
6 NAcc mRNA stability Brme1 0.03 0.02 3.4e-03 0.03 0.02 0.02 0.02 6.0e-04 2.4e-03 4.5e-03 9.4e-04
7 Brain mRNA stability Brme1 0.06 0.03 2.8e-05 0.06 0.04 0.04 0.05 1.6e-06 5.6e-05 1.4e-04 1.2e-05
8 pVTA gene expression Brme1 0.11 0.06 1.6e-04 0.03 0.06 0.05 0.02 2.7e-02 2.0e-03 2.3e-03 3.9e-02
9 BLA intron excision ratio chr19_24000264_24011422 0.09 0.05 2.8e-04 0.06 0.03 0 0.03 5.9e-04 1.1e-02 2.2e-01 1.2e-02
10 Brain isoform ratio XM_039098080.1 0.02 0.01 7.1e-03 0.03 0.02 0.02 0.03 8.4e-04 2.9e-03 1.0e-02 1.9e-03
11 Brain gene expression Brme1 0.03 0.02 3.8e-03 0 0.01 0.01 0 1.8e-01 7.7e-02 8.8e-02 2.1e-01
12 Adipose isoform ratio XR_005496718.1 0.1 0.05 1.6e-08 0.07 0.06 0.06 0.07 1.7e-08 1.4e-07 4.2e-07 2.4e-08
13 BLA isoform ratio XM_039098080.1 0.05 0.03 8.3e-03 0.02 0.03 0.02 0.01 3.3e-02 1.5e-02 3.6e-02 9.5e-02
14 Adipose gene expression Brme1 0.04 0.02 8.8e-04 0.01 0.02 0.02 0.02 1.0e-02 2.3e-03 2.6e-03 3.0e-03
15 PL gene expression Brme1 0.12 0.06 2.8e-08 0.05 0.07 0.07 0.07 2.0e-06 4.7e-08 1.4e-08 6.4e-08
16 NAcc intron excision ratio chr19_23997612_24000090 0.04 0.03 7.1e-03 0.01 -0 -0 0 4.3e-02 4.3e-01 7.9e-01 1.3e-01
17 PL isoform ratio XM_039098080.1 0.04 0.03 1.1e-03 0.04 0.02 0.03 -0 1.2e-05 4.0e-03 5.0e-04 9.3e-01
18 PL intron excision ratio chr19_23997612_24000090 0.05 0.03 9.0e-05 0.04 0.04 0.03 0 1.9e-05 3.9e-05 3.3e-04 3.5e-01
19 BLA gene expression Brme1 0.28 0.1 1.7e-10 0.17 0.17 0.19 0.17 3.3e-09 1.8e-09 2.7e-10 2.7e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.72.98.42.92.9-1.21.90.82.21.80.9-2.8-2.20.1-1.12.0-0.50.5-1.3-1.3-1.3-0.4
Area under the delay curve0.20.20.6-0.5-0.50.8-0.2-0.6-0.4-0.20.7-0.7-0.60.6-0.30.30.4-0.5-0.2-0.2-0.2-0.1
BMI with tail1.23.810.3-2.7-2.7-0.1-1.8-0.3-2.7-2.6-2.42.13.2-1.0-0.4-2.6-1.20.71.91.81.70.1
BMI without tail0.10.30.7-0.8-0.80.6-0.3-0.6-0.6-0.8-0.30.40.40.30.2-0.40.2-0.50.00.0-0.1-0.7
Body weight0.10.62.3-0.6-0.6-0.60.30.6-0.3-0.3-1.51.51.4-0.90.5-0.9-0.30.10.40.50.4-0.7
Weight adjusted by age0.40.41.1-1.0-1.00.1-1.0-0.1-0.8-1.00.20.6-0.1-0.20.1-0.5-0.20.40.80.60.61.1
Bone surface2.34.07.52.42.40.22.0-0.52.71.82.0-2.5-2.71.50.52.61.2-1.3-2.4-2.4-2.4-1.5
Bone volume2.23.88.42.72.7-0.22.0-0.22.91.91.7-2.5-2.91.10.52.50.8-0.9-2.2-2.1-2.2-1.2
Breakpoint value in progressive ratio session4.55.011.9-0.3-0.3-2.8-0.32.9-0.5-0.1-3.42.52.8-3.1-0.2-2.3-2.82.72.52.52.51.6
Number of licking bursts0.40.53.50.60.6-0.70.70.7-0.40.9-0.5-0.80.2-0.5-1.90.3-0.60.5-0.3-0.3-0.2-1.0
Context. condit. distance diff. score0.70.83.0-1.6-1.60.3-1.0-0.3-1.7-0.4-0.71.30.8-0.2-0.2-1.10.1-0.00.70.80.8-0.1
Locomotion velocity, session 10.70.82.11.51.5-0.11.40.41.41.0-0.1-1.0-0.4-0.1-0.01.0-0.2-0.2-1.0-0.9-0.9-0.9
Locomotion distance, session 10.40.61.40.70.7-1.21.01.20.20.5-1.1-0.20.8-0.9-1.00.1-0.90.8-0.0-0.0-0.0-0.7
Locomotion velocity, session 20.40.51.51.01.0-0.31.00.60.31.00.1-1.1-0.5-0.2-1.20.7-0.30.3-0.4-0.4-0.4-0.6
Locomotion distance, session 20.60.92.8-0.0-0.0-1.20.51.3-0.60.2-1.70.61.5-1.3-1.1-0.7-1.11.10.60.60.6-0.6
Locomotion velocity, session 30.20.20.7-0.2-0.20.8-0.2-0.80.0-0.30.5-0.1-0.40.60.50.10.6-0.8-0.3-0.3-0.3-0.2
Locomotion distance, session 31.92.03.90.40.41.20.8-1.40.20.81.8-1.6-1.41.8-0.41.71.8-1.6-1.8-1.8-1.8-2.0
Stereotopy head waving bouts, day 31.41.66.1-0.9-0.92.5-1.0-2.2-0.2-1.11.5-0.2-0.91.91.30.31.7-1.9-0.7-0.8-0.8-0.5
Stereotopy head waving duration, day 30.50.52.9-0.8-0.81.7-0.9-1.1-0.7-1.00.6-0.0-0.10.90.2-0.20.7-0.8-0.0-0.1-0.1-0.1
Locomotion velocity, session 70.20.20.9-0.7-0.70.5-0.2-0.6-0.9-0.0-0.00.10.20.4-0.4-0.10.4-0.5-0.3-0.2-0.2-0.9
Locomotion distance, session 70.20.20.60.30.3-0.70.70.8-0.10.4-0.80.10.4-0.6-0.7-0.1-0.60.50.10.10.1-0.5
Stereotopy head waving bouts, day 72.22.55.60.40.41.90.4-1.60.30.52.4-1.8-2.42.1-0.31.81.9-1.8-1.7-1.7-1.7-1.4
Stereotopy head waving duration, day 71.72.04.50.70.71.50.6-1.30.50.72.0-1.9-2.11.8-0.41.71.5-1.4-1.6-1.7-1.7-1.3
Locomotion velocity, session 80.20.20.9-0.0-0.0-0.50.60.60.20.6-1.00.80.6-0.60.5-0.3-0.20.00.00.00.0-0.6
Locomotion distance, session 80.60.82.4-0.7-0.7-0.90.10.8-1.30.3-1.50.81.5-1.1-1.2-0.9-0.80.80.60.60.6-0.7
Degree of sensitization distance1.91.94.5-0.2-0.2-1.5-0.11.8-0.2-0.4-2.11.51.5-2.00.0-1.5-1.81.61.51.61.61.2
Degree of sensitization stereotypy1.01.12.50.00.01.50.1-1.2-0.20.11.6-1.2-1.51.5-0.41.11.4-1.3-1.1-1.1-1.1-1.0
Conditioned locomotion0.10.10.20.30.3-0.40.40.30.40.4-0.30.20.1-0.30.30.1-0.1-0.0-0.1-0.2-0.2-0.2
Cocaine response after cond. corrected1.11.23.5-0.7-0.7-1.0-0.41.0-0.7-0.1-1.91.51.7-1.5-0.0-1.4-1.21.11.21.21.20.4
Cocaine response after cond. not corrected1.61.84.9-0.6-0.6-1.4-0.31.4-0.7-0.0-2.21.51.8-1.9-0.4-1.6-1.71.61.51.41.40.6
Cocaine response before conditioning0.20.30.90.70.7-0.10.60.10.40.60.3-1.0-0.70.1-0.70.6-0.10.1-0.4-0.4-0.5-0.4
Saline control response1.82.47.51.61.6-2.72.12.70.81.7-1.7-0.30.7-2.0-1.70.3-1.81.70.10.20.1-0.5
Bone: connectivity density3.04.813.83.33.3-0.52.40.42.52.31.8-3.7-2.80.9-1.32.90.2-0.2-2.1-2.1-2.1-1.3
Bone: cortical apparent density0.40.52.2-0.7-0.70.9-0.7-1.0-1.5-0.50.7-0.70.30.8-1.30.00.4-0.3-0.1-0.1-0.1-0.5
Bone: cortical area0.10.21.20.20.2-0.40.90.30.20.6-0.20.1-0.3-0.0-0.00.40.3-0.2-0.6-0.5-0.6-1.1
Bone: cortical porosity0.60.62.7-0.9-0.90.0-0.70.1-0.2-0.8-0.31.70.6-0.41.1-0.80.20.10.80.80.81.2
Bone: cortical porosity0.30.41.9-0.8-0.80.3-0.4-0.3-0.0-0.40.11.40.30.21.3-0.30.8-0.50.10.10.10.3
Bone: cortical thickness0.61.03.4-1.6-1.60.0-0.80.0-1.8-0.9-1.01.51.5-0.4-0.5-1.2-0.10.30.80.80.8-0.2
Bone: cortical thickness4.45.111.7-0.2-0.2-2.6-0.32.8-1.9-0.5-2.80.52.2-2.9-3.3-1.8-3.23.42.52.42.51.5
Bone: cortical tissue density0.40.51.8-0.6-0.61.0-0.6-1.0-1.3-0.40.8-0.90.21.0-1.20.20.6-0.4-0.3-0.3-0.3-0.7
Condit. Reinf. active minus inactive responses2.22.56.8-1.6-1.62.1-0.2-2.3-1.6-0.41.7-0.3-0.62.20.20.72.6-2.1-1.4-1.3-1.3-2.2
Condit. Reinf. active-inactive response ratio0.70.83.5-1.6-1.60.7-0.4-1.0-1.9-0.50.40.60.40.7-0.3-0.31.2-0.6-0.1-0.1-0.1-1.0
Condit. Reinf. active responses1.72.15.2-0.8-0.82.10.2-2.0-0.90.01.9-0.9-0.92.10.11.12.3-1.9-1.5-1.5-1.5-2.0
Condit. Reinf. inactive responses1.61.93.51.71.70.61.6-0.21.81.31.4-1.9-1.50.90.11.90.7-0.9-1.6-1.6-1.7-1.1
Incentive salience index mean2.83.47.7-0.2-0.22.10.8-2.2-0.10.32.4-1.4-1.52.60.41.82.8-2.4-2.3-2.3-2.2-2.6
Condit. Reinf. lever presses2.93.86.51.21.21.81.3-1.61.51.02.5-2.0-2.02.30.72.42.3-2.1-2.5-2.5-2.5-2.1
Condit. Reinf. active minus inactive responses0.40.51.10.20.20.50.6-0.50.70.20.5-0.1-0.80.81.00.60.9-1.0-1.0-0.9-0.9-1.0
Condit. Reinf. active-inactive response ratio0.10.11.0-0.3-0.30.1-0.3-0.10.1-0.4-0.10.7-0.00.01.0-0.30.2-0.20.10.10.20.3
Condit. Reinf. active responses0.10.10.40.30.3-0.00.60.20.5-0.0-0.30.1-0.20.00.40.20.0-0.2-0.4-0.4-0.3-0.6
Condit. Reinf. inactive responses0.40.51.3-0.1-0.1-0.60.10.9-0.1-0.6-1.10.60.8-1.0-0.3-0.7-1.00.90.80.80.70.5
Condit. Reinf. lever presses0.10.10.2-0.2-0.20.1-0.40.1-0.2-0.5-0.40.3-0.1-0.2-0.0-0.5-0.40.30.40.40.50.4
Condit. Reinf. lever reinforcers received0.00.10.20.20.20.10.40.10.5-0.2-0.10.1-0.40.00.40.10.0-0.2-0.2-0.2-0.2-0.2
Conditioned reinforcement - actives0.10.10.4-0.1-0.1-0.0-0.20.0-0.1-0.1-0.10.40.0-0.10.7-0.20.1-0.10.10.20.30.4
Conditioned reinforcement - inactives0.20.21.0-0.1-0.10.5-0.4-0.6-0.10.00.40.2-0.50.51.00.00.6-0.7-0.4-0.10.00.1
Conditioned locomotion0.10.10.3-0.2-0.20.5-0.2-0.5-0.3-0.4-0.10.10.30.30.2-0.20.1-0.4-0.20.0-0.1-0.3
Patch foraging indifference point 0 sec0.50.82.3-0.5-0.50.50.5-0.70.40.20.70.2-0.21.11.30.71.5-1.2-0.9-1.2-1.1-1.5
Patch foraging indifference point AUC0.91.03.01.71.7-1.41.31.31.41.4-0.6-0.6-0.3-1.0-0.30.5-1.10.8-0.2-0.1-0.10.3
Delay disc. indifference point, 0s delay0.50.62.00.90.90.21.1-0.21.40.60.3-1.1-0.90.20.60.9-0.0-0.5-0.8-1.0-0.9-0.6
Delay disc. indifference point, 16s delay0.90.91.8-1.1-1.1-0.3-0.90.5-1.1-0.5-1.00.81.0-0.9-0.4-1.2-1.00.81.11.31.31.1
Delay disc. indifference point, 2s delay0.40.41.4-0.9-0.90.9-1.2-0.8-1.0-0.50.90.1-0.30.60.2-0.20.5-0.20.30.30.20.8
Delay disc. indifference point, 24s delay0.40.41.5-1.2-1.20.9-0.5-0.7-0.8-0.10.60.2-0.00.70.3-0.01.1-0.9-0.20.00.0-0.4
Delay disc. indifference point, 4s delay0.80.92.90.90.90.70.5-0.60.60.41.5-1.7-1.50.9-0.51.30.5-0.5-0.9-1.1-1.0-0.1
Delay disc. indifference point, 8s delay0.40.41.0-1.0-1.01.0-0.2-0.9-0.7-0.70.7-0.7-0.50.8-0.30.30.6-0.8-0.3-0.2-0.3-0.4
Indifference point function ln k1.52.06.1-2.0-2.02.5-1.3-2.2-1.4-1.61.20.3-0.21.80.8-0.21.9-1.7-0.4-0.5-0.5-0.9
Indifference point function log k1.52.06.1-2.0-2.02.5-1.3-2.2-1.4-1.61.20.3-0.21.80.8-0.21.9-1.7-0.4-0.5-0.5-0.9
Patch foraging total patch changes 0 sec0.30.61.7-0.9-0.90.40.1-0.60.0-0.30.40.70.30.81.30.21.3-1.0-0.5-0.8-0.7-1.2
Patch foraging total patch changes 12 sec0.81.03.01.11.1-0.91.70.80.81.7-0.1-0.7-0.1-0.1-0.61.20.3-0.2-1.2-1.2-1.0-1.7
Patch foraging total patch changes 18 sec1.62.06.02.32.3-1.52.51.31.91.9-0.2-1.2-0.6-0.4-0.61.5-0.30.2-1.2-1.3-1.2-1.3
Patch foraging total patch changes 24 sec1.01.33.11.31.3-0.51.80.51.51.50.5-0.8-0.80.40.41.40.7-0.5-1.4-1.5-1.4-1.6
Patch foraging total patch changes 6 sec0.20.30.90.90.9-0.90.90.80.80.8-0.2-0.3-0.2-0.4-0.40.5-0.40.4-0.2-0.3-0.3-0.3
Patch foraging time to switch 0 sec0.10.20.70.40.4-0.80.40.6-0.00.5-0.2-0.20.0-0.5-0.90.1-0.40.50.10.10.1-0.0
Patch foraging water rate 0 sec0.10.20.9-0.2-0.2-0.10.00.30.4-0.6-0.60.90.6-0.30.9-0.5-0.20.10.40.30.20.2
Patch foraging water rate 12 sec0.60.94.1-0.5-0.52.0-0.7-1.8-0.8-1.31.2-0.6-0.61.4-0.30.20.9-1.0-0.3-0.5-0.3-0.3
Patch foraging water rate 18 sec2.12.86.30.10.12.4-0.1-2.30.3-0.32.4-1.5-1.92.50.81.52.2-2.3-2.0-1.7-1.7-1.2
Patch foraging water rate 24 sec1.01.44.1-0.7-0.72.0-0.4-2.0-0.4-0.51.5-0.7-0.91.80.30.61.6-1.6-1.0-1.0-1.1-1.1
Patch foraging water rate 6 sec1.42.05.92.42.4-0.92.31.02.11.6-0.0-1.7-1.0-0.3-0.71.5-0.60.3-1.2-1.2-1.2-1.0
Seeking ratio, delayed vs. immediate footshock1.11.34.2-1.5-1.50.6-1.4-0.6-2.0-1.8-0.30.31.2-0.0-2.1-1.0-0.40.81.30.90.70.6
Distance traveled before self-admin0.50.52.5-0.5-0.5-0.2-0.90.1-0.4-0.60.01.10.3-0.31.3-0.7-0.00.30.80.80.91.6
Distance traveled after self-admin0.40.52.3-0.2-0.20.2-1.1-0.3-0.5-0.70.21.0-0.20.01.1-0.70.0-0.00.40.80.81.5
Extensor digitorum longus weight0.31.12.8-0.6-0.6-1.4-0.31.1-0.6-0.5-1.51.71.6-1.20.3-1.2-0.81.01.01.11.10.5
Bone: elastic displacement0.60.71.9-1.1-1.11.2-0.6-1.4-0.7-0.70.30.60.40.90.9-0.21.0-1.1-0.3-0.4-0.3-0.7
Bone: elastic work0.81.12.8-1.7-1.70.5-1.2-0.6-1.4-1.5-0.91.61.5-0.00.6-1.30.1-0.20.70.70.7-0.0
Bone: endosteal estimation0.40.92.71.21.2-1.61.31.60.81.0-1.1-0.20.1-1.1-0.50.2-1.00.8-0.1-0.1-0.1-0.6
Bone: endosteal perimeter0.91.94.31.41.4-0.62.10.41.71.90.4-0.6-1.50.40.61.60.9-0.9-1.7-1.7-1.7-2.0
Epididymis fat weight0.30.83.20.20.2-1.80.61.40.30.5-1.51.00.8-1.4-0.0-0.6-1.01.10.60.60.70.2
Delta time in closed arm before/after self-admin0.60.62.0-1.4-1.40.8-1.0-0.9-1.1-1.20.60.30.20.6-0.2-0.40.7-0.20.50.30.20.2
Delta time in open arm before/after self-admin2.52.46.91.81.8-2.62.12.61.72.0-2.10.00.8-2.0-0.20.1-1.71.40.10.10.2-0.7
Diff in mean of infusions in LGA sessions0.20.30.80.30.3-0.90.60.90.40.2-0.80.00.4-0.8-0.2-0.1-0.80.70.30.20.2-0.1
Delay discount exponential model param0.30.30.90.50.5-0.90.30.70.60.2-0.90.80.7-0.70.4-0.4-0.60.60.40.30.30.2
Extinction: sum of active levers before priming1.11.14.0-2.0-2.01.4-1.3-1.2-1.6-1.6-0.00.20.90.6-0.4-0.90.2-0.30.80.30.3-0.3
Active lever presses in extinction session 61.31.33.7-0.1-0.11.7-0.3-1.50.1-0.31.3-0.7-0.61.61.50.71.5-1.9-1.3-0.9-1.0-0.9
Bone: final force0.30.41.60.30.3-1.30.51.20.50.2-1.10.70.6-1.00.3-0.4-0.70.70.40.40.40.1
Bone: final moment0.20.41.30.20.2-1.10.41.10.20.0-1.00.70.7-0.90.1-0.4-0.70.60.30.30.3-0.0
Food consumed during 24 hour testing period3.84.510.53.23.2-3.23.13.02.32.8-1.3-1.7-0.4-1.9-1.91.3-2.11.9-0.6-0.6-0.7-0.8
Glucose0.20.43.9-0.1-0.10.10.0-0.01.0-0.1-0.31.00.4-0.02.0-0.20.3-0.6-0.1-0.1-0.20.1
Heart weight1.01.35.0-1.5-1.51.6-1.3-1.4-2.2-1.40.9-0.90.41.1-2.1-0.10.5-0.40.1-0.00.1-0.4
Delay discount hyperbolic model param0.40.41.20.50.5-0.90.20.80.60.1-1.11.00.8-0.80.6-0.6-0.60.50.40.30.40.2
Intermittent access intake day 1-15 change1.41.43.61.91.9-0.31.50.31.41.80.5-1.3-1.30.3-0.51.40.3-0.4-1.5-1.1-1.1-1.1
Intermittent access intake escalation1.61.64.42.12.1-0.61.70.61.62.10.3-1.2-1.20.0-0.31.40.1-0.3-1.5-1.0-1.1-1.0
Intermittent access intake escalation 21.81.83.92.02.0-0.11.70.11.61.90.6-1.5-1.40.5-0.11.60.5-0.7-1.7-1.4-1.5-1.4
Intermitt. access day 1 inactive lever presses1.21.32.80.10.11.50.2-1.50.6-0.01.1-0.9-0.81.51.60.91.3-1.7-1.2-1.4-1.3-1.3
Intermitt. access day 15 inactive lever presses0.40.41.1-0.3-0.3-0.3-0.60.3-0.3-0.5-0.81.10.9-0.51.0-0.9-0.40.20.50.80.80.6
Intermitt. access escalation Index0.20.10.40.50.5-0.40.50.40.40.4-0.4-0.30.2-0.3-0.60.2-0.50.2-0.2-0.2-0.2-0.5
Intermittent access day 1 total infusions0.80.92.1-1.4-1.40.4-1.3-0.4-1.0-1.4-0.61.11.0-0.11.0-1.2-0.20.11.00.90.90.7
Intermittent access day 15 total infusions0.10.10.80.20.20.20.0-0.20.30.20.20.0-0.40.30.90.10.4-0.4-0.3-0.1-0.1-0.1
Intermittent access terminal intake (last 3 days)0.10.21.6-0.0-0.00.4-0.2-0.40.1-0.00.20.2-0.20.41.3-0.10.5-0.6-0.3-0.1-0.1-0.1
Intermittent access total infusions0.10.21.3-0.4-0.40.3-0.5-0.3-0.2-0.4-0.20.50.30.11.1-0.40.2-0.40.10.30.30.1
Intermittent access day 1 locomotion0.50.61.8-1.1-1.10.8-0.9-0.8-0.7-1.4-0.60.51.10.20.8-0.9-0.2-0.40.40.30.3-0.3
Intermittent access day 15 total locomotion1.11.22.6-0.7-0.7-0.8-0.80.7-0.6-0.7-1.61.61.5-1.20.7-1.6-1.10.81.21.41.40.9
Intermittent access total locomotion1.31.53.4-1.2-1.2-0.4-1.10.4-0.9-1.2-1.71.71.8-1.00.9-1.8-1.10.71.31.51.40.8
Intermittent access standard deviation1.51.63.20.60.61.50.2-1.50.30.51.8-1.0-1.61.80.71.21.7-1.8-1.7-1.2-1.2-0.9
Left kidney weight0.20.61.71.01.0-1.01.31.10.21.1-0.2-0.5-0.3-0.4-1.10.7-0.10.3-0.6-0.5-0.4-0.9
Right kidney weight0.20.52.00.30.3-1.21.01.3-0.50.8-0.80.20.5-0.8-1.40.1-0.30.8-0.1-0.0-0.0-1.0
Cocaine induced anxiety0.20.21.0-0.2-0.20.5-0.2-0.60.1-0.10.60.1-0.60.61.00.20.7-0.6-0.3-0.2-0.20.1
Post-drug Anxiety0.40.51.4-0.9-0.90.5-1.2-0.5-1.2-0.80.20.80.20.20.1-0.60.3-0.10.40.80.81.0
Baseline Anxiety1.11.22.3-0.3-0.3-1.3-0.41.3-0.6-0.2-1.31.11.2-1.5-0.9-1.0-1.31.51.31.31.31.3
Tail length1.64.910.32.72.70.32.60.13.02.82.0-1.9-3.21.21.02.81.6-1.6-2.6-2.4-2.5-1.7
Length with tail0.51.95.32.02.0-0.61.90.82.22.30.8-0.4-1.70.11.21.60.9-0.6-1.4-1.2-1.2-0.6
Length without tail0.61.33.2-0.3-0.3-1.3-0.51.3-0.5-0.1-1.51.81.5-1.50.4-1.2-0.91.11.21.31.51.2
Times rat made contact with spout0.10.11.00.20.2-0.10.00.1-0.20.20.0-0.60.0-0.1-1.00.1-0.40.30.10.10.0-0.0
Lifetime Intake0.20.21.8-0.3-0.30.3-0.4-0.3-0.0-0.3-0.00.50.10.21.3-0.30.3-0.40.00.20.20.2
Liver weight, left0.91.53.81.51.5-1.81.32.00.91.1-1.4-0.40.2-1.6-1.20.0-1.71.60.30.40.30.1
Liver weight, right0.61.02.81.11.1-1.51.31.70.81.1-1.40.00.8-1.3-0.40.0-1.11.00.1-0.1-0.0-0.6
Locomotor activity1.72.65.90.10.1-1.9-0.31.9-0.8-0.7-2.41.02.2-2.2-1.4-1.6-2.42.21.81.61.71.0
Locomotor testing distance1.83.06.90.30.3-2.2-0.42.1-0.7-0.8-2.40.91.9-2.3-1.6-1.6-2.62.51.91.81.81.3
Locomotor testing rearing1.32.17.21.71.7-2.31.42.30.21.0-1.3-0.90.1-1.7-2.70.2-1.91.90.20.30.3-0.1
Locomotion in novel chamber2.43.05.7-0.7-0.7-2.0-0.52.0-1.3-0.5-2.31.12.3-2.2-2.2-1.6-2.32.41.91.81.91.0
Locomotion in novel chamber post-restriction0.10.20.40.50.50.20.2-0.20.6-0.1-0.5-0.40.20.00.5-0.0-0.5-0.2-0.2-0.5-0.4-0.6
Fecal boli incidents, locomotor time 11.61.74.51.71.7-0.31.60.32.11.81.0-0.5-1.30.51.51.61.2-0.8-1.3-1.3-1.5-0.9
Change in fecal boli incidents, locomotor task1.11.03.70.40.41.10.4-1.00.00.01.3-1.9-1.31.2-1.21.10.5-0.7-1.0-1.2-1.1-0.9
Time >=10cm from walls, locomotor time 10.40.42.00.70.7-0.5-0.20.5-0.30.20.3-0.5-0.7-0.3-1.40.2-0.61.00.40.30.20.8
Bouts of movement, locomotor time 10.60.61.7-0.1-0.11.2-0.3-1.1-0.10.11.3-0.5-1.21.10.50.61.1-1.1-0.8-0.6-0.5-0.1
Total resting periods, locomotor time 10.91.02.8-0.4-0.41.7-0.6-1.5-0.4-0.11.6-0.5-1.21.50.70.61.5-1.5-0.9-0.7-0.5-0.2
Rest time, locomotor task time 11.01.13.1-0.6-0.61.7-0.7-1.5-0.4-0.61.40.0-0.81.61.20.41.8-1.6-0.9-0.7-0.5-0.5
Distance moved, locomotor task time 11.41.53.8-0.1-0.1-1.5-0.21.4-0.3-0.1-1.90.81.3-1.7-0.8-1.2-2.01.61.31.41.21.0
Vertical activity count, locomotor time 12.52.68.01.91.9-2.81.82.81.51.7-1.4-0.00.1-2.2-1.10.2-2.02.00.60.80.61.2
Time >=10cm from walls, locomotor time 20.80.83.5-0.8-0.8-0.1-1.20.0-0.4-0.8-0.51.20.5-0.60.6-1.1-0.60.51.11.21.21.9
Bouts of movement, locomotor time 20.40.41.4-0.8-0.80.6-1.0-0.6-1.2-1.00.4-0.00.10.3-0.8-0.4-0.00.00.30.50.40.8
Total resting periods, locomotor time 20.20.20.8-0.4-0.40.2-0.7-0.2-0.9-0.60.3-0.0-0.00.1-0.8-0.3-0.20.30.30.50.40.8
Rest time, locomotor task time 20.20.30.70.90.9-0.30.60.30.40.60.3-0.6-0.7-0.1-0.70.5-0.00.4-0.1-0.3-0.4-0.2
Distance moved, locomotor task time 21.61.83.6-1.7-1.70.0-1.7-0.1-1.2-1.5-1.21.81.5-0.80.9-1.9-0.70.31.31.71.71.5
Vertical activity count, locomotor time 20.70.72.10.50.5-1.40.91.40.60.5-1.20.60.8-1.40.2-0.3-1.10.60.20.80.80.8
Light reinforcement 15.610.230.25.05.0-3.35.53.44.44.8-0.6-2.7-1.8-1.5-1.33.1-1.11.0-2.3-2.4-2.3-2.4
Light reinforcement 24.96.617.14.14.1-3.24.13.23.94.1-0.7-1.4-1.7-1.6-0.02.2-1.11.0-1.6-1.4-1.4-1.1
Bone: marrow area0.40.82.81.11.1-1.61.21.70.81.0-1.1-0.10.2-1.2-0.60.1-1.10.9-0.00.0-0.0-0.5
Bone: maximum diameter0.51.02.80.10.10.70.9-0.70.50.90.8-0.1-1.11.00.71.01.5-1.4-1.3-1.3-1.3-1.7
Bone: maximum force0.10.20.70.10.1-0.80.40.60.50.1-0.80.80.4-0.60.7-0.3-0.30.20.10.10.1-0.2
Bone: maximum moment0.10.20.60.00.0-0.70.40.60.30.1-0.80.80.5-0.50.6-0.2-0.20.1-0.00.0-0.0-0.4
Mean time between licks in bursts0.30.41.6-0.4-0.40.40.1-0.6-1.00.30.3-0.60.10.5-1.20.40.4-0.4-0.6-0.6-0.5-1.3
Mean num. licks in bursts0.30.41.1-0.4-0.40.9-0.7-1.00.2-0.80.80.0-0.40.71.0-0.10.5-0.50.10.1-0.10.8
Cd content in liver0.70.72.6-0.3-0.31.00.4-0.8-0.70.50.9-0.7-0.11.0-0.60.81.1-1.0-1.0-0.9-1.1-1.6
Co content in liver1.92.37.0-1.8-1.82.6-1.3-2.6-1.2-1.11.60.2-0.12.10.90.12.1-2.1-0.7-0.7-0.8-0.9
Cu content in liver0.30.31.6-0.9-0.90.2-0.4-0.3-1.3-0.4-0.10.40.80.3-0.5-0.40.5-0.30.10.10.1-0.8
Fe content in liver1.11.33.50.10.11.7-0.2-1.61.2-0.11.6-0.2-1.21.41.90.81.5-1.6-1.0-1.0-0.90.1
K content in liver0.30.31.1-0.5-0.50.0-0.30.0-0.0-0.9-1.00.70.9-0.30.5-0.8-0.5-0.10.30.30.3-0.3
Mg content in liver0.50.51.6-0.8-0.81.0-0.6-0.9-0.1-1.3-0.40.70.70.51.0-0.50.4-1.0-0.2-0.2-0.1-0.7
Mn content in liver0.20.21.1-0.1-0.1-0.40.40.30.2-0.4-0.60.40.9-0.10.4-0.10.2-0.4-0.3-0.3-0.3-1.0
Na content in liver0.40.41.40.40.4-0.5-0.10.80.6-0.2-0.90.10.4-0.90.1-0.5-1.20.70.60.60.71.0
Rb content in liver0.10.20.50.20.20.30.2-0.40.40.30.2-0.1-0.10.40.40.30.5-0.6-0.6-0.6-0.5-0.7
Se content in liver1.82.24.30.90.91.31.0-1.02.10.71.5-0.6-1.71.51.91.61.8-2.0-1.8-1.8-1.7-1.1
Sr content in liver0.40.41.2-0.9-0.9-0.3-0.4-0.1-0.5-0.9-0.81.11.1-0.10.5-0.70.3-0.10.30.30.3-0.6
Zn content in liver0.40.41.8-0.8-0.8-0.7-0.40.3-1.3-0.3-0.40.60.7-0.3-0.8-0.6-0.10.60.60.60.6-0.0
Bone: minimum diameter0.81.54.01.81.8-1.52.01.21.71.9-0.3-0.8-0.9-0.6-0.21.1-0.40.3-1.0-0.9-1.0-1.1
Time in familiar zone, hab. session 10.70.61.80.50.50.50.8-0.2-0.11.01.0-1.3-1.00.6-1.31.10.5-0.4-0.8-0.8-0.8-0.8
Time in novel zone, hab. session 11.11.12.8-0.8-0.8-0.2-1.5-0.1-0.6-1.6-0.70.80.8-0.50.4-1.3-1.00.81.31.31.31.7
Total zone transitions, hab. session 10.50.71.80.90.9-1.30.61.30.50.6-1.0-0.10.5-1.2-0.7-0.2-1.31.20.50.50.50.4
Total locomotion distance, hab. session 10.30.51.70.60.6-0.70.31.00.30.1-1.1-0.00.9-1.0-0.5-0.4-1.30.90.50.50.50.3
Locomotion velocity, hab. session 10.40.61.60.80.8-1.00.61.20.60.4-1.30.01.1-1.1-0.4-0.3-1.30.90.40.30.30.0
Time in familiar zone, hab. session 20.80.82.21.21.2-0.31.50.40.81.30.3-1.2-0.50.1-0.71.20.1-0.3-1.1-1.1-1.1-1.2
Time in novel zone, hab. session 22.52.54.5-1.9-1.9-0.2-2.00.1-2.0-1.8-1.31.81.5-0.9-0.2-2.1-1.01.22.02.02.01.6
Total zone transitions, hab. session 20.60.72.11.21.2-0.61.30.90.40.9-0.5-1.10.1-0.4-1.40.7-0.70.4-0.6-0.6-0.6-1.2
Total locomotion distance, hab. session 20.40.61.50.80.8-0.91.01.20.40.4-1.2-0.11.1-1.0-0.6-0.0-1.00.70.0-0.0-0.0-0.6
Locomotion velocity, hab. session 20.40.61.60.90.9-1.01.01.30.70.5-1.20.01.0-1.0-0.40.0-1.00.70.0-0.0-0.0-0.5
Novel to familiar place preference ratio1.01.01.8-0.7-0.7-0.6-1.00.5-1.2-0.9-1.00.51.1-0.9-1.1-1.2-1.21.21.41.31.31.0
Novelty place preference1.41.52.5-0.6-0.6-0.9-1.00.8-1.2-0.8-1.30.61.3-1.3-1.2-1.4-1.61.51.61.51.51.3
Time in novel zone, NPP test1.41.52.7-0.8-0.8-0.5-1.30.4-1.3-1.2-1.10.61.2-1.0-0.9-1.5-1.41.31.61.61.61.5
Total zone transitions, NPP test0.60.82.71.11.1-1.11.71.00.91.4-0.6-0.40.2-0.5-0.30.8-0.20.2-0.8-0.8-0.8-1.5
Total locomotion distance, NPP test0.10.20.60.50.5-0.60.70.60.20.3-0.6-0.20.6-0.4-0.50.1-0.40.3-0.2-0.2-0.2-0.8
Locomotion velocity, NPP test0.30.41.40.50.5-0.81.10.80.40.8-0.80.10.7-0.5-0.10.2-0.20.2-0.4-0.4-0.4-1.2
Intraocular pressure1.42.05.5-2.3-2.31.8-2.2-1.6-2.2-1.90.41.10.70.80.2-1.20.8-0.70.80.90.90.7
Delta distance traveled before/after self-admin0.00.10.4-0.1-0.10.4-0.2-0.4-0.1-0.6-0.0-0.1-0.00.2-0.2-0.1-0.0-0.2-0.1-0.1-0.0-0.2
Delta ambulatory time before/after self-admin0.40.40.90.70.70.50.4-0.50.40.30.5-0.9-0.70.6-0.60.70.3-0.6-1.0-0.7-0.7-0.8
Parametrial fat weight0.10.30.90.70.7-0.80.70.71.00.8-0.40.2-0.2-0.50.60.2-0.20.1-0.3-0.0-0.10.1
Pavlov. Cond. lever latency0.81.02.70.20.2-1.60.21.4-0.60.2-1.2-0.10.7-1.3-1.6-0.5-1.51.60.90.90.90.4
Pavlov. Cond. magazine entry latency0.50.62.0-0.9-0.91.4-1.2-1.3-0.4-1.20.60.30.10.90.8-0.40.7-0.70.20.10.20.6
Pavlov. Cond. change in total contacts1.41.52.70.40.41.50.6-1.21.20.31.4-0.6-1.21.51.41.21.6-1.6-1.4-1.5-1.5-1.0
Pavlov. Cond. index score0.81.13.7-0.7-0.71.9-0.7-1.70.1-0.71.10.2-0.41.41.50.21.5-1.6-0.6-0.7-0.7-0.3
Pavlov. Cond. latency score0.60.72.5-0.4-0.41.6-0.3-1.30.3-0.30.90.2-0.41.21.30.31.3-1.4-0.7-0.7-0.7-0.5
Pavlov. Cond. lever contacts0.70.83.4-0.3-0.31.5-0.4-1.20.6-0.60.90.4-0.51.11.80.21.2-1.3-0.5-0.5-0.50.0
Pavlov. Cond. magazine entry number1.11.44.51.11.1-2.11.32.10.11.3-1.2-0.30.3-1.6-1.70.1-1.51.60.30.40.4-0.2
Pavlov. Cond. intertrial magazine entries1.41.74.2-0.1-0.11.30.9-1.20.50.51.3-0.1-1.01.51.51.22.1-2.0-1.5-1.5-1.6-1.8
Pavlov. Cond. lever-magazine prob. diff.0.91.13.7-1.0-1.01.9-1.1-1.70.0-1.00.90.7-0.21.31.8-0.21.4-1.5-0.3-0.4-0.40.0
Pavlov. Cond. response bias1.01.24.0-0.8-0.82.0-1.2-1.80.1-1.31.20.3-0.31.41.8-0.11.3-1.4-0.2-0.3-0.30.4
Pavlov. Cond. lever latency0.10.10.6-0.5-0.5-0.4-0.10.0-0.20.3-0.20.80.5-0.20.4-0.30.20.10.20.30.20.2
Pavlov. Cond. magazine entry latency0.10.10.40.00.00.10.10.1-0.10.40.1-0.1-0.60.1-0.20.20.3-0.1-0.2-0.2-0.2-0.4
Pavlov. Cond. change in total contacts0.30.41.30.20.21.1-0.1-0.70.2-0.30.9-0.8-1.01.00.10.60.7-0.8-0.6-0.7-0.6-0.4
Pavlov. Cond. index score0.20.20.90.40.40.7-0.0-0.20.3-0.10.5-0.7-1.00.5-0.10.40.3-0.4-0.4-0.4-0.4-0.3
Pavlov. Cond. latency score0.20.21.00.40.40.70.0-0.30.3-0.00.5-0.7-1.00.60.10.50.3-0.4-0.4-0.5-0.4-0.3
Pavlov. Cond. lever contacts0.10.10.50.60.6-0.00.20.30.2-0.0-0.1-0.7-0.4-0.1-0.70.2-0.40.3-0.0-0.1-0.0-0.0
Pavlov. Cond. magazine entry number0.10.10.7-0.0-0.0-0.60.00.2-0.10.0-0.40.10.8-0.5-0.4-0.3-0.60.50.30.40.30.4
Pavlov. Cond. intertrial magazine entries0.91.13.51.51.5-1.11.90.91.21.40.1-1.2-0.5-0.3-0.71.3-0.20.2-1.0-1.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.20.20.7-0.1-0.30.1-0.20.4-0.5-0.70.5-0.10.30.3-0.4-0.3-0.3-0.3-0.3
Pavlov. Cond. response bias0.00.00.10.20.20.2-0.10.20.1-0.3-0.1-0.2-0.3-0.0-0.1-0.0-0.20.00.10.00.10.0
Time in closed arm before self-admin0.70.81.80.90.90.80.3-0.80.50.41.2-1.2-1.41.0-0.41.10.5-0.7-1.2-1.1-1.2-0.5
Time in closed arm after self-admin0.30.31.5-0.4-0.40.6-0.4-0.6-0.3-0.51.2-0.3-0.90.7-0.50.40.7-0.10.0-0.3-0.30.5
Time in open arm before self-admin0.60.61.8-1.3-1.31.0-1.2-0.9-1.1-1.00.60.50.10.60.1-0.50.7-0.40.40.60.60.6
Time in open arm after self-admin0.50.62.1-0.4-0.4-0.7-0.20.8-0.30.0-1.40.81.2-1.00.1-1.0-0.90.70.80.90.90.1
Bone: periosteal estimation0.40.92.71.31.3-1.51.61.50.91.4-0.7-0.4-0.3-0.8-0.70.6-0.60.5-0.5-0.5-0.5-1.1
Bone: periosteal perimeter0.81.45.10.80.8-0.21.80.20.81.70.4-0.5-1.10.5-0.11.31.0-0.9-1.6-1.5-1.6-2.2
Bone: post-yield work0.50.71.91.41.4-1.30.91.31.10.7-0.4-0.6-0.5-0.9-0.40.4-0.91.00.10.10.10.4
Progressive ratio test 1 active lever presses1.11.22.2-1.5-1.50.2-1.4-0.2-1.0-1.4-0.71.41.1-0.31.4-1.4-0.20.11.21.11.10.9
Progressive ratio test 1 breakpoint0.90.91.8-1.4-1.40.3-1.3-0.3-0.9-1.3-0.51.20.9-0.21.3-1.2-0.10.01.00.90.90.8
Progressive ratio test 1 inactive lever presses0.40.56.5-0.3-0.30.5-0.4-0.50.3-0.40.10.5-0.00.42.5-0.30.6-0.8-0.1-0.0-0.00.1
Progressive ratio test 2 active lever presses0.30.40.9-0.9-0.90.5-0.9-0.5-0.7-0.80.00.70.30.20.8-0.70.3-0.20.40.50.50.5
Progressive ratio test 2 breakpoint0.50.51.1-1.0-1.00.1-1.0-0.2-0.9-0.9-0.31.00.5-0.10.6-0.9-0.00.10.70.90.80.8
Progressive ratio test 2 inactive lever presses1.01.12.6-1.3-1.30.4-1.6-0.4-1.2-1.4-0.51.41.0-0.11.4-1.4-0.0-0.10.91.21.20.9
Incentive Sensitization - Responses0.20.20.70.20.20.40.0-0.40.00.30.8-0.3-0.90.6-0.00.50.7-0.5-0.5-0.3-0.4-0.2
Incentive Sensitization - Breakpoint0.20.20.80.20.20.40.1-0.40.10.40.9-0.4-0.90.6-0.10.50.7-0.5-0.6-0.3-0.4-0.2
Sum of active levers in priming session hrs 5-60.40.31.30.50.5-0.70.80.80.30.3-0.7-0.40.5-0.7-1.10.1-0.80.60.00.00.0-0.5
Progressive ratio0.50.63.10.80.8-0.90.91.40.20.3-0.4-0.6-0.1-0.7-1.80.3-0.61.20.3-0.1-0.2-0.4
Food seeking constrained by brief footshock1.41.74.01.81.8-0.31.80.51.72.00.6-1.1-1.30.4-0.41.60.6-0.6-1.5-1.6-1.4-1.4
Seeking ratio, punishment vs. effort0.60.82.40.50.50.50.3-0.91.00.90.7-0.1-0.70.81.50.71.0-1.5-1.3-0.9-0.7-0.5
Retroperitoneal fat weight0.62.07.1-0.5-0.5-2.10.52.0-0.30.2-2.72.32.1-2.10.4-1.4-1.21.21.01.11.1-0.3
Reaction time number correct0.91.24.1-1.5-1.52.0-1.1-1.6-1.1-1.31.10.1-0.51.50.5-0.21.4-1.4-0.2-0.2-0.3-0.3
Reaction time mean minus median0.40.62.3-1.1-1.10.4-1.0-0.7-0.6-0.50.11.2-0.20.21.5-0.80.6-0.50.40.70.70.7
Reaction time mean minus median AUC0.91.23.2-1.6-1.60.8-1.5-0.8-1.1-1.0-0.21.70.50.21.8-1.30.6-0.50.70.90.80.7
Reaction time num false alarms1.01.35.0-2.0-2.00.5-1.2-0.2-2.2-1.2-0.51.21.6-0.1-1.0-1.10.30.20.90.90.90.0
Reaction time num false alarms AUC0.81.14.3-1.8-1.81.0-1.3-0.7-2.1-1.30.10.71.10.4-1.0-0.80.5-0.10.50.60.6-0.0
Reaction time trials correct on left0.91.24.1-1.5-1.52.0-1.1-1.6-1.1-1.31.10.1-0.51.50.5-0.21.4-1.4-0.2-0.2-0.3-0.3
Reaction time trials on left0.81.23.9-1.6-1.62.0-1.2-1.5-1.2-1.31.00.2-0.51.40.5-0.31.3-1.3-0.1-0.1-0.2-0.3
Reaction time mean1.82.66.0-2.5-2.50.5-2.4-0.9-2.2-1.7-0.72.21.3-0.31.1-2.10.10.11.61.71.71.4
Reaction time mean AUC1.92.55.8-2.4-2.40.6-2.4-0.8-2.1-1.8-0.72.11.3-0.31.1-2.10.00.11.51.71.61.3
Median of all reaction times2.02.86.5-2.6-2.60.4-2.4-0.8-2.3-1.9-0.82.11.6-0.40.8-2.2-0.10.31.71.81.71.3
Reaction time omissions1.31.85.5-1.7-1.7-0.5-1.50.4-1.7-0.9-0.82.30.7-0.80.5-1.7-0.10.71.51.71.81.5
Reaction time false alarm rate0.20.31.2-0.8-0.80.1-0.5-0.0-1.1-0.5-0.30.51.1-0.2-0.8-0.5-0.00.30.40.40.5-0.0
Reaction time premature initiation rate3.85.110.73.23.2-0.63.30.82.93.10.9-2.6-2.30.5-0.52.70.5-0.9-2.6-2.5-2.3-2.5
Reaction time premature initiations2.33.35.52.02.00.32.30.12.02.11.2-2.2-2.21.0-0.32.21.0-1.2-2.3-2.2-2.1-2.3
Std. dev. reaction times0.60.92.2-1.3-1.30.2-1.4-0.6-1.1-0.5-0.11.5-0.1-0.11.2-1.20.30.00.81.21.11.2
Reaction time trials completed0.81.23.9-1.6-1.62.0-1.2-1.5-1.2-1.31.00.2-0.51.40.5-0.31.3-1.3-0.1-0.1-0.2-0.3
Reaction time trials AUC0.81.23.5-1.7-1.71.9-1.3-1.4-1.3-1.40.80.3-0.31.20.5-0.41.2-1.10.10.0-0.0-0.1
Run reversals in cocaine runway, females2.82.75.9-1.5-1.5-1.2-1.01.2-0.7-1.4-2.02.42.1-1.71.3-2.1-1.01.12.02.12.01.5
Run reversals in cocaine runway, males0.50.52.3-0.2-0.20.2-1.1-0.2-1.2-0.40.60.4-0.40.1-1.5-0.30.00.70.60.50.51.4
Latency to leave start box in cocaine runway1.51.63.1-0.3-0.3-1.7-0.41.4-0.4-0.1-1.71.51.6-1.80.5-1.3-1.41.41.31.61.71.2
Latency to leave start box in cocaine runway, F1.21.32.3-0.7-0.7-0.9-0.90.7-0.3-0.7-1.41.51.4-1.21.3-1.4-1.10.91.41.41.51.4
Latency to leave start box in cocaine runway, M1.41.34.91.21.2-2.21.61.90.81.7-1.40.40.6-1.6-0.20.1-1.01.0-0.10.50.4-0.4
Std. dev. time between licks in bursts0.81.02.21.21.2-0.61.40.60.51.50.3-1.4-0.70.1-1.31.20.10.1-1.0-1.0-1.0-1.4
Total sessions with >9 infusions2.02.26.6-1.8-1.82.3-1.6-2.3-1.0-1.81.00.50.01.72.6-0.61.5-1.9-0.1-0.2-0.2-0.2
Short access day 1 total inactive lever presses0.50.67.70.60.6-0.60.40.51.10.6-0.40.8-0.1-0.32.8-0.10.2-0.3-0.10.10.10.3
Short access day 10 total inactive lever presses1.31.42.51.11.10.61.2-0.61.60.90.8-1.2-1.00.91.41.30.9-1.3-1.5-1.5-1.5-1.4
Short access day 1 total infusions2.12.314.0-1.8-1.81.8-1.7-1.9-0.7-1.70.61.10.01.33.7-0.91.5-1.60.30.20.30.4
Short access day 10 total infusions0.20.31.3-0.0-0.0-0.4-0.10.40.2-0.2-0.90.80.7-0.51.2-0.6-0.50.10.30.50.40.2
Short access total infusions0.30.44.2-0.4-0.40.3-0.5-0.30.1-0.40.00.80.00.22.1-0.40.5-0.60.10.20.30.4
Short access day 1 locomotion1.21.37.1-1.5-1.51.2-1.4-1.3-0.7-1.40.31.00.30.82.7-0.90.9-1.00.50.30.30.3
Short access day 10 total locomotion0.60.72.1-1.2-1.20.9-1.1-0.9-1.1-1.4-0.70.41.50.1-0.1-1.0-0.4-0.30.40.40.3-0.3
Short access total locomotion1.11.23.0-1.5-1.51.6-1.4-1.6-1.0-1.7-0.10.61.00.81.6-0.90.5-1.10.20.20.1-0.3
One hour access (0.3 mA shock)0.00.00.1-0.1-0.10.3-0.2-0.3-0.10.00.1-0.0-0.30.20.2-0.10.2-0.3-0.10.0-0.0-0.2
Compulsive drug intake2.22.23.70.60.61.70.7-1.70.60.61.9-1.9-1.71.9-0.11.71.6-1.8-1.8-1.8-1.8-1.7
One hour access (shock baseline)1.01.22.1-0.9-0.9-0.7-1.00.7-1.1-0.8-1.21.31.3-1.1-0.5-1.4-1.01.11.31.41.41.1
Social response proportion1.01.02.0-0.9-0.9-0.9-0.51.0-1.0-0.4-1.21.31.4-1.1-0.6-1.1-0.81.21.41.11.10.6
Social responses0.70.98.0-0.1-0.1-0.80.21.1-1.2-0.0-0.9-0.10.9-0.9-2.8-0.3-1.01.30.60.50.5-0.4
Social time0.60.81.90.70.70.50.4-0.60.20.51.3-1.4-1.31.1-0.81.20.9-0.7-1.2-1.0-0.9-0.8
Soleus weight0.10.40.8-0.2-0.2-0.60.00.8-0.7-0.4-0.60.30.7-0.7-0.8-0.5-0.70.90.70.80.70.4
Bone: stiffness0.60.92.30.50.5-1.50.51.51.00.3-1.21.10.5-1.50.7-0.5-1.01.00.70.80.70.9
Tibialis anterior weight0.10.51.5-1.0-1.00.9-0.4-1.0-0.9-0.60.60.6-0.10.90.5-0.01.2-0.9-0.3-0.3-0.3-0.6
Time to tail flick, vehicle, before self-admin0.30.30.80.70.7-0.50.80.50.90.60.2-0.5-0.8-0.2-0.10.5-0.40.50.1-0.4-0.50.2
Time to tail flick, vehicle, after self-admin1.61.75.90.90.9-2.21.32.20.71.1-0.8-0.10.1-1.7-2.40.3-1.32.10.90.50.50.7
Time to tail flick, test, before self-admin0.90.92.9-1.1-1.1-0.0-1.30.1-0.8-0.7-0.51.70.8-0.31.4-1.20.20.10.91.21.11.2
Time to tail flick, test, after self-admin0.10.20.80.30.3-0.60.30.70.20.9-0.10.0-0.2-0.4-0.40.1-0.20.50.20.20.10.2
Delta time to tail flick, vehicle, before/after SA0.30.30.80.50.5-0.90.70.90.50.9-0.00.0-0.1-0.5-0.80.40.00.5-0.00.10.0-0.0
Delta time to tail flick, test, before/after SA0.10.10.80.20.20.10.2-0.1-0.10.60.3-0.5-0.40.2-0.90.40.20.0-0.3-0.3-0.3-0.3
Tibia length0.20.73.80.50.50.70.2-0.51.60.20.70.2-1.20.61.90.50.8-1.0-0.6-0.6-0.70.1
Ambulatory time before self-admin1.11.13.1-0.8-0.8-0.4-1.10.3-0.6-0.9-0.61.71.0-0.71.7-1.3-0.40.41.11.31.31.8
Ambulatory time after self-admin0.20.31.60.50.5-0.3-0.40.20.0-0.1-0.10.7-0.2-0.30.9-0.3-0.30.10.10.60.71.3
Bone: tissue strength0.50.51.3-0.9-0.90.9-0.5-0.8-0.4-0.40.40.90.30.71.2-0.21.1-1.1-0.3-0.3-0.3-0.4
Total heroin consumption0.80.92.9-0.3-0.3-1.0-0.11.1-0.5-0.2-1.70.71.7-1.3-0.6-1.0-1.31.00.90.90.9-0.0
Bone: trabecular number2.84.512.33.13.1-0.01.8-0.32.71.82.3-3.5-3.21.4-0.52.80.6-0.6-2.1-2.1-2.1-0.7
Bone: trabecular spacing2.22.97.1-2.5-2.50.2-1.8-0.1-2.3-1.4-1.72.72.2-1.00.3-2.3-0.50.41.81.71.70.7
Bone: trabecular thickness0.50.61.81.31.3-1.10.70.71.30.5-0.2-0.8-0.8-0.4-0.00.4-0.80.8-0.1-0.1-0.10.4
Bone: trabecular tissue density2.23.15.7-1.5-1.5-0.8-1.70.7-1.3-1.5-1.72.32.0-1.60.3-2.3-1.41.42.32.32.32.4
Water consumed over 24 hours0.91.02.41.51.5-1.41.21.40.70.9-0.8-1.10.2-1.0-1.60.4-1.41.1-0.0-0.0-0.0-0.2
Number of responses in last shaping day1.51.55.2-1.6-1.61.7-1.6-1.7-1.0-1.60.80.80.11.22.3-0.71.2-1.30.30.20.20.4