Hub : Genes

Brinp3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS NM_173121.2 0.05 0.03 1.6e-03 0.01 0.02 0.02 0.01 1.6e-02 1.2e-02 7.1e-03 2.2e-02
2 Brain intron excision ratio chr13_60975265_60985571 0.13 0.06 4.1e-10 0.12 0.11 0.11 0.11 2.2e-11 3.2e-10 2.1e-10 1.3e-10
3 NAcc intron excision ratio chr13_60966205_60985571 0.02 0.01 9.4e-03 0.01 0.01 0 0.01 1.6e-02 1.2e-02 6.0e-02 4.0e-02
4 PL intron excision ratio chr13_60975265_60985571 0.15 0.08 1.2e-11 0.1 0.1 0.11 0.11 4.3e-11 1.9e-11 6.7e-12 8.1e-12
5 IC intron excision ratio chr13_60975265_60985571 0.1 0.07 5.2e-03 0.05 0.05 0.03 0.04 2.8e-03 5.0e-03 2.7e-02 5.5e-03
6 Brain alternative TSS XM_039090416.2 0.04 0.03 3.9e-03 0.01 0.01 0 0 1.9e-02 4.4e-02 2.8e-01 9.8e-02
7 NAcc intron excision ratio chr13_60975265_60985571 0.09 0.05 3.8e-10 0.06 0.07 0.06 0.06 4.1e-09 1.4e-10 8.7e-09 2.4e-09
8 BLA intron excision ratio chr13_61195637_61248356 0.06 0.04 3.9e-03 0.03 0.04 0.01 0.03 8.0e-03 3.9e-03 9.3e-02 1.1e-02
9 IL alternative polyA NM_173121.2 0.42 0.17 1.8e-03 0.13 0.06 0.04 0.12 5.6e-04 1.3e-02 4.5e-02 9.4e-04
10 Brain gene expression Brinp3 0.12 0.11 6.7e-05 0.03 0.06 0.05 0.05 1.7e-03 2.0e-06 2.8e-05 2.9e-05
11 BLA intron excision ratio chr13_61166085_61195447 0.06 0.04 2.4e-03 0.04 0.04 0.02 0.04 4.6e-03 2.2e-03 2.2e-02 4.3e-03
12 Brain intron excision ratio chr13_60964515_60985571 0.04 0.03 3.4e-03 0.02 0.02 0.02 0 3.3e-03 3.7e-03 2.9e-03 9.6e-02
13 IL alternative polyA XM_017598680.3 0.39 0.17 3.6e-03 0.07 0.04 0.03 0.1 1.1e-02 3.7e-02 8.3e-02 2.4e-03
14 PL intron excision ratio chr13_60966205_60985571 0.02 0.02 8.7e-03 0.01 0 0 0 1.5e-02 1.7e-01 3.7e-01 1.4e-01
15 Brain mRNA stability Brinp3 0.18 0.07 0.0e+00 0.26 0.25 0.26 0.26 9.8e-25 1.3e-23 2.0e-24 3.2e-24
16 Brain intron excision ratio chr13_61195637_61248356 0.04 0.02 2.4e-04 0.03 0.04 0.04 0.04 6.6e-04 1.9e-04 1.7e-04 2.8e-04
17 IC gene expression Brinp3 0.3 0.18 3.1e-06 0.09 0.11 0.07 0.11 1.7e-04 2.3e-05 7.7e-04 3.2e-05
18 Adipose gene expression Brinp3 0.65 0.23 0.0e+00 0.41 0.42 0.46 0.46 9.9e-49 1.1e-50 6.0e-57 5.9e-57
19 Brain intron excision ratio chr13_61166085_61195447 0.04 0.02 2.7e-04 0.03 0.04 0.03 0.03 1.4e-03 2.9e-04 4.1e-04 5.7e-04
20 Brain alternative TSS XM_017598680.3 0.04 0.02 4.5e-04 0.02 0.03 0.03 0.04 4.2e-03 5.8e-04 6.5e-04 2.4e-04
21 Brain alternative TSS XM_017598680.3 0.04 0.03 2.8e-04 0.02 0.03 0.04 0.04 2.6e-03 3.5e-04 3.0e-04 2.0e-04
22 pVTA intron excision ratio chr13_60975265_60985571 0.3 0.13 1.1e-11 0.14 0.11 0.17 0.16 9.9e-12 7.5e-09 7.9e-14 1.8e-12
23 Brain isoform ratio XM_017598680.3 0.03 0.02 3.7e-03 0.04 0.02 0.01 0.03 2.6e-04 8.0e-03 4.0e-02 5.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density2.84.914.1-2.82.7-2.53.02.82.92.12.33.8-3.1-2.2-2.1-3.6-1.31.41.41.90.6-1.00.10.30.01.0
Area under the delay curve0.10.10.30.2-0.30.2-0.2-0.3-0.3-0.30.30.10.2-0.30.4-0.3-0.30.20.40.50.4-0.4-0.5-0.5-0.5-0.6
BMI with tail1.86.114.7-3.83.4-3.53.23.63.73.32.52.5-2.3-2.4-2.7-2.0-1.81.81.81.41.3-1.3-0.10.01.40.9
BMI without tail0.61.94.1-1.71.5-1.71.71.71.91.51.72.0-1.5-1.6-1.1-1.7-1.21.21.11.30.6-0.9-0.4-0.4-0.20.1
Body weight2.812.129.1-5.44.9-4.94.75.25.34.63.43.9-3.7-3.2-4.1-3.0-2.32.32.01.81.4-1.50.10.41.41.6
Weight adjusted by age0.30.51.3-0.60.6-0.30.30.80.80.2-0.30.9-1.00.4-0.8-0.40.6-0.8-0.8-0.7-0.80.81.01.10.01.2
Bone surface3.36.011.5-3.43.2-3.23.33.33.33.02.73.0-2.5-2.6-2.5-2.8-1.92.01.91.91.4-1.5-0.3-0.11.00.8
Bone volume3.25.710.4-3.13.0-3.03.13.03.12.72.83.2-2.5-2.7-2.0-3.1-1.92.12.12.21.4-1.6-0.5-0.40.70.6
Breakpoint value in progressive ratio session0.60.72.0-0.30.7-0.80.60.40.10.81.30.4-0.4-1.3-0.0-0.5-1.11.01.21.41.0-1.2-0.9-0.80.7-0.6
Number of licking bursts0.71.13.81.8-1.21.3-1.1-2.0-2.0-1.5-0.20.7-0.30.21.4-0.90.3-0.4-0.30.7-0.60.0-0.4-0.5-1.7-0.9
Context. condit. distance diff. score2.53.17.31.3-1.21.9-1.1-1.2-1.3-2.0-2.10.5-1.02.10.30.02.4-2.4-2.3-1.8-2.72.31.81.7-2.21.2
Locomotion velocity, session 10.80.92.3-0.80.6-0.20.40.81.00.2-0.9-0.0-0.71.0-0.90.51.1-1.1-1.0-1.4-1.01.31.51.50.31.5
Locomotion distance, session 11.01.33.2-0.40.10.3-0.20.60.6-0.3-1.4-0.1-0.41.4-0.70.61.5-1.6-1.3-1.8-1.41.61.81.70.11.6
Locomotion velocity, session 20.30.41.0-0.20.20.2-0.10.30.3-0.2-0.8-0.2-0.20.8-0.40.41.0-0.9-0.7-1.0-0.70.90.90.90.10.8
Locomotion distance, session 21.31.83.90.7-0.91.3-0.8-0.5-0.4-1.3-2.0-0.80.32.0-0.10.91.9-2.0-1.7-2.0-1.61.81.61.5-0.31.1
Locomotion velocity, session 32.02.36.2-0.70.70.10.30.70.7-0.2-1.70.1-1.31.7-1.30.52.0-2.0-1.9-2.1-1.82.22.52.50.12.4
Locomotion distance, session 32.22.45.80.2-0.00.8-0.3-0.2-0.3-0.8-2.0-0.4-1.02.1-0.50.82.3-2.2-1.9-2.1-1.92.32.42.40.22.0
Stereotopy head waving bouts, day 33.74.310.60.3-0.51.4-0.3-0.10.0-1.6-2.40.9-1.62.5-1.10.12.9-3.0-3.1-2.6-3.33.02.72.6-2.42.1
Stereotopy head waving duration, day 31.82.15.40.1-0.10.80.10.10.1-0.9-1.60.5-1.21.7-1.20.32.0-2.0-2.3-1.8-2.32.11.91.9-1.51.6
Locomotion velocity, session 70.80.94.1-1.10.8-0.71.01.51.40.40.52.0-1.3-0.5-0.6-1.8-0.10.10.20.2-0.10.10.40.5-1.20.7
Locomotion distance, session 70.30.41.1-0.60.5-0.30.60.70.60.2-0.30.8-0.90.3-0.7-0.70.5-0.5-0.4-0.5-0.50.70.90.9-0.21.0
Stereotopy head waving bouts, day 72.12.48.12.1-2.02.2-1.8-1.7-1.7-2.4-1.50.10.31.41.40.01.5-1.4-1.5-0.8-1.81.20.40.3-2.8-0.4
Stereotopy head waving duration, day 71.01.25.51.4-1.41.6-1.3-1.1-1.0-1.7-1.00.20.11.00.9-0.01.1-1.0-1.2-0.6-1.40.90.30.2-2.3-0.2
Locomotion velocity, session 82.12.55.11.0-1.01.6-1.1-0.8-0.7-1.7-2.10.2-0.62.10.30.22.2-2.3-2.0-1.9-2.22.21.91.8-1.61.3
Locomotion distance, session 83.24.69.91.1-1.01.9-1.1-0.9-0.9-2.0-2.9-0.1-0.92.9-0.10.73.1-3.1-2.9-2.8-3.13.12.72.6-1.72.0
Degree of sensitization distance1.41.42.6-1.21.0-1.31.31.21.31.21.61.2-0.4-1.6-0.7-1.4-1.51.41.21.31.2-1.3-0.9-0.90.1-0.4
Degree of sensitization stereotypy1.41.53.91.8-1.91.6-1.8-1.5-1.5-1.7-0.5-0.51.30.42.00.20.3-0.2-0.10.1-0.4-0.1-0.9-1.0-2.0-1.4
Conditioned locomotion3.23.77.1-2.52.5-2.72.12.32.32.62.41.5-1.3-2.4-1.4-1.4-2.01.92.01.81.7-1.8-0.8-0.71.70.1
Cocaine response after cond. corrected1.51.84.6-0.70.9-0.21.10.40.30.2-1.00.5-1.91.1-2.10.21.5-1.4-1.8-1.3-1.61.62.02.00.32.1
Cocaine response after cond. not corrected1.61.94.5-0.40.60.20.60.20.2-0.2-1.30.4-1.61.4-1.80.41.8-1.7-2.0-1.6-1.81.92.12.10.02.1
Cocaine response before conditioning1.01.23.71.6-1.71.5-1.9-1.3-1.1-1.4-0.8-1.21.80.71.80.80.3-0.4-0.2-0.40.00.1-0.5-0.6-0.6-1.1
Saline control response0.81.02.31.0-0.81.2-0.6-1.0-1.0-1.3-1.3-0.0-0.31.3-0.10.11.4-1.5-1.5-1.0-1.51.30.90.9-0.60.6
Bone: connectivity density2.03.17.2-2.52.4-2.12.42.52.61.91.52.7-2.5-1.3-2.1-2.4-0.50.70.80.90.1-0.30.70.80.61.4
Bone: cortical apparent density1.11.53.9-0.40.20.1-0.30.40.4-0.0-1.5-0.7-0.31.5-0.71.31.5-1.6-1.5-2.0-1.31.71.91.90.41.7
Bone: cortical area3.14.710.5-3.23.2-3.02.93.13.02.82.22.5-2.4-2.1-2.5-2.0-1.61.51.31.30.9-1.10.20.31.01.2
Bone: cortical porosity2.12.27.7-1.81.8-1.12.11.91.81.0-0.11.5-2.10.2-2.8-0.80.9-0.8-1.1-0.7-1.01.01.81.90.62.0
Bone: cortical porosity1.92.17.1-1.61.7-1.02.01.61.50.8-0.21.5-2.20.3-2.7-0.91.0-0.9-1.1-0.7-1.11.11.81.90.52.0
Bone: cortical thickness1.11.95.1-2.01.9-1.61.82.12.11.41.22.3-1.8-1.2-1.5-1.8-0.70.60.40.70.0-0.40.30.4-0.60.9
Bone: cortical thickness0.40.51.6-0.10.20.20.50.10.0-0.3-0.31.2-1.20.3-0.9-0.90.7-0.9-0.9-0.2-1.00.71.00.9-0.70.8
Bone: cortical tissue density1.31.74.6-0.40.20.2-0.30.40.4-0.1-1.6-0.8-0.41.7-0.81.41.7-1.7-1.6-2.1-1.41.82.02.00.41.8
Condit. Reinf. active minus inactive responses0.20.21.0-0.50.3-0.10.50.50.50.2-0.3-0.20.00.4-1.00.20.5-0.3-0.5-0.5-0.20.40.70.70.50.6
Condit. Reinf. active-inactive response ratio0.91.03.0-0.90.8-0.81.21.01.00.71.31.5-0.7-1.2-0.7-1.7-0.91.11.01.30.9-0.9-0.6-0.6-0.2-0.2
Condit. Reinf. active responses1.11.33.40.0-0.30.7-0.10.1-0.0-0.6-1.6-1.00.31.6-1.01.21.6-1.5-1.6-1.8-1.21.51.51.50.31.2
Condit. Reinf. inactive responses2.22.77.50.1-0.30.7-0.7-0.1-0.2-0.5-2.2-2.20.62.2-0.82.72.0-2.0-2.2-2.7-1.82.12.02.00.61.6
Incentive salience index mean0.10.10.5-0.1-0.10.10.20.30.2-0.0-0.0-0.40.7-0.0-0.40.1-0.00.20.1-0.10.4-0.2-0.1-0.10.3-0.2
Condit. Reinf. lever presses0.30.52.30.6-0.80.5-0.4-0.4-0.4-0.50.3-0.71.5-0.30.6-0.1-0.60.60.70.60.9-0.8-0.9-1.0-0.0-1.1
Condit. Reinf. active minus inactive responses0.20.20.6-0.20.20.00.2-0.00.1-0.0-0.40.3-0.60.4-0.80.10.4-0.5-0.7-0.5-0.70.60.70.7-0.20.7
Condit. Reinf. active-inactive response ratio0.40.50.90.7-0.50.7-0.7-0.8-0.7-0.7-0.9-0.40.10.9-0.00.70.8-0.8-1.0-0.8-0.80.80.60.6-0.50.4
Condit. Reinf. active responses0.30.41.0-0.30.3-0.00.30.10.3-0.0-0.40.5-0.70.5-1.0-0.10.6-0.6-1.0-0.6-1.00.70.80.9-0.50.9
Condit. Reinf. inactive responses0.70.91.9-1.41.2-1.31.41.31.41.20.90.9-0.9-0.9-1.2-1.0-0.70.70.50.50.2-0.4-0.00.00.50.5
Condit. Reinf. lever presses0.60.82.7-0.20.30.30.40.20.3-0.5-0.51.6-1.40.5-0.8-1.30.9-0.9-1.0-0.4-1.41.01.01.0-1.31.0
Condit. Reinf. lever reinforcers received0.50.61.9-0.10.10.30.1-0.1-0.0-0.3-0.80.4-0.80.8-0.90.10.9-1.0-1.4-0.9-1.41.11.11.1-0.61.1
Conditioned reinforcement - actives0.30.51.50.5-0.50.9-1.0-0.5-0.3-1.0-0.70.5-0.60.70.3-0.51.0-1.0-0.7-0.3-1.20.80.60.5-0.70.3
Conditioned reinforcement - inactives0.81.15.0-1.21.2-0.71.01.11.10.40.32.0-2.2-0.3-1.4-1.80.5-0.5-0.30.3-1.00.40.80.9-0.41.1
Conditioned locomotion0.70.91.8-0.80.5-0.90.10.80.90.91.20.20.4-1.30.2-0.5-1.11.21.41.21.2-1.3-1.2-1.10.6-0.9
Patch foraging indifference point 0 sec0.40.82.21.4-1.41.2-1.5-1.2-1.1-1.3-0.40.00.70.31.4-0.20.2-0.4-0.10.1-0.2-0.0-0.4-0.5-1.2-0.8
Patch foraging indifference point AUC0.10.20.9-0.70.6-0.6-0.10.40.40.70.1-0.70.3-0.1-0.30.8-0.20.10.3-0.20.3-0.10.20.21.00.1
Delay disc. indifference point, 0s delay0.10.10.4-0.50.4-0.30.50.20.20.20.30.5-0.7-0.3-0.4-0.6-0.10.00.10.4-0.0-0.10.10.10.40.2
Delay disc. indifference point, 16s delay0.50.61.40.1-0.3-0.0-0.1-0.3-0.30.00.80.00.5-0.90.6-0.5-1.00.91.01.21.0-1.1-1.2-1.2-0.2-1.2
Delay disc. indifference point, 2s delay0.30.30.6-0.80.7-0.70.50.80.80.70.70.6-0.5-0.7-0.2-0.5-0.50.40.50.50.5-0.5-0.3-0.2-0.0-0.0
Delay disc. indifference point, 24s delay1.31.43.40.7-1.10.7-0.8-0.9-0.9-0.80.90.50.6-1.01.7-1.1-1.01.01.21.61.1-1.3-1.7-1.7-1.6-1.9
Delay disc. indifference point, 4s delay0.20.21.0-0.10.00.0-0.2-0.2-0.30.1-0.5-1.00.50.5-0.21.00.4-0.4-0.3-0.7-0.00.40.40.40.70.4
Delay disc. indifference point, 8s delay0.10.20.70.1-0.20.20.0-0.1-0.2-0.20.40.4-0.1-0.40.4-0.6-0.30.20.50.60.3-0.4-0.4-0.5-0.9-0.5
Indifference point function ln k0.40.73.1-0.50.6-0.61.30.70.70.40.91.7-1.0-0.9-0.8-1.8-0.60.70.41.00.2-0.5-0.4-0.3-0.40.1
Indifference point function log k0.40.73.1-0.50.6-0.61.30.70.70.40.91.7-1.0-0.9-0.8-1.8-0.60.70.41.00.2-0.5-0.4-0.3-0.40.1
Patch foraging total patch changes 0 sec0.50.92.71.6-1.51.3-1.6-1.3-1.3-1.3-0.3-0.10.80.31.6-0.20.1-0.30.00.2-0.1-0.1-0.5-0.6-1.2-1.0
Patch foraging total patch changes 12 sec1.01.42.91.5-1.21.5-1.7-1.6-1.6-1.4-1.4-0.90.61.40.80.91.2-1.4-1.1-1.0-1.01.00.60.6-0.5-0.0
Patch foraging total patch changes 18 sec0.81.24.61.6-1.61.5-2.0-1.6-1.5-1.5-0.8-0.60.90.82.10.40.6-0.70.0-0.3-0.30.3-0.1-0.2-1.0-0.7
Patch foraging total patch changes 24 sec0.10.20.90.7-0.60.5-0.9-0.7-0.7-0.4-0.2-0.60.60.20.80.50.1-0.20.00.0-0.0-0.1-0.2-0.3-0.2-0.6
Patch foraging total patch changes 6 sec0.10.10.6-0.0-0.1-0.1-0.6-0.00.00.2-0.0-0.80.8-0.00.20.7-0.1-0.10.2-0.10.3-0.2-0.1-0.10.5-0.4
Patch foraging time to switch 0 sec0.40.92.81.3-1.40.9-0.9-0.8-1.0-0.90.0-0.91.4-0.11.70.4-0.30.40.60.40.8-0.6-1.1-1.1-0.6-1.2
Patch foraging water rate 0 sec0.20.40.8-0.90.9-0.80.50.60.70.70.80.8-0.6-0.8-0.6-0.8-0.70.70.60.70.4-0.5-0.1-0.10.20.1
Patch foraging water rate 12 sec0.40.71.5-0.60.5-0.70.90.70.60.61.21.1-0.5-1.2-0.4-1.2-1.11.20.81.20.5-1.0-0.8-0.8-0.5-0.5
Patch foraging water rate 18 sec0.40.61.4-0.91.0-0.91.20.60.60.80.91.0-1.1-0.8-1.0-1.1-0.70.60.40.90.2-0.5-0.2-0.10.50.3
Patch foraging water rate 24 sec0.20.32.40.4-0.30.5-0.0-0.5-0.5-0.60.11.0-0.7-0.1-0.0-1.0-0.1-0.1-0.20.6-0.4-0.0-0.2-0.2-1.6-0.3
Patch foraging water rate 6 sec0.40.61.7-0.81.0-0.81.10.70.60.60.91.3-1.1-0.8-0.8-1.3-0.60.60.30.80.1-0.4-0.2-0.1-0.50.2
Seeking ratio, delayed vs. immediate footshock0.91.13.21.8-1.61.3-1.4-1.6-1.7-1.3-0.2-0.71.30.11.80.0-0.10.30.50.60.3-0.5-0.9-1.0-0.4-1.2
Distance traveled before self-admin0.91.24.01.6-1.71.6-1.0-1.6-1.6-1.7-0.10.40.30.11.4-0.60.10.0-0.20.8-0.1-0.2-0.8-0.9-2.0-1.3
Distance traveled after self-admin0.70.82.41.2-0.91.2-0.1-0.9-1.6-1.5-0.21.1-1.20.20.5-1.30.5-0.6-0.70.7-1.00.40.0-0.0-1.5-0.3
Extensor digitorum longus weight0.52.15.8-1.91.8-1.21.71.81.81.1-0.31.0-2.00.4-2.4-0.20.9-0.8-1.1-1.1-1.01.21.81.90.52.2
Bone: elastic displacement0.30.31.7-0.0-0.00.1-0.40.10.10.0-0.7-1.00.40.7-0.21.30.7-0.5-0.7-1.0-0.60.60.50.50.50.3
Bone: elastic work0.20.30.8-0.70.9-0.70.60.70.60.70.60.6-0.8-0.6-0.6-0.5-0.30.40.30.40.1-0.30.00.00.40.1
Bone: endosteal estimation0.71.54.3-1.41.4-1.71.11.11.11.91.3-0.3-0.0-1.3-1.00.2-1.31.41.20.91.4-1.2-0.7-0.72.1-0.2
Bone: endosteal perimeter2.55.410.1-2.93.0-3.22.62.52.53.22.91.6-1.6-2.8-1.9-1.7-2.52.62.42.22.0-2.1-0.9-0.82.40.3
Epididymis fat weight0.72.36.3-2.52.1-2.21.82.42.52.11.41.0-1.1-1.3-1.8-0.7-0.80.81.30.71.0-0.80.20.31.20.8
Delta time in closed arm before/after self-admin0.70.61.70.3-0.5-0.0-0.9-0.4-0.20.10.5-0.81.3-0.61.00.5-0.90.81.00.51.0-1.0-1.2-1.20.1-1.2
Delta time in open arm before/after self-admin0.30.31.00.5-0.50.80.0-0.6-0.6-0.8-0.60.2-0.50.6-0.2-0.20.8-0.7-1.0-0.3-0.90.70.50.4-0.50.2
Diff in mean of infusions in LGA sessions0.91.12.6-0.91.0-1.01.10.80.70.91.51.5-1.2-1.5-0.4-1.6-1.11.01.21.60.5-1.0-0.7-0.6-0.1-0.3
Delay discount exponential model param0.10.10.5-0.30.4-0.30.30.30.40.4-0.2-0.1-0.20.2-0.50.30.2-0.2-0.3-0.5-0.30.30.50.50.70.6
Extinction: sum of active levers before priming0.30.41.70.9-0.80.8-0.3-1.1-1.3-0.8-0.00.3-0.30.00.5-0.40.2-0.3-0.10.5-0.2-0.1-0.3-0.3-1.0-0.6
Active lever presses in extinction session 60.80.81.7-0.20.4-0.60.6-0.1-0.30.61.20.10.1-1.20.3-0.4-1.31.11.31.31.3-1.3-1.1-1.10.5-0.9
Bone: final force2.74.39.2-3.03.0-2.92.82.72.72.92.31.8-1.9-2.2-2.3-1.6-1.91.71.61.41.4-1.3-0.10.01.50.8
Bone: final moment2.94.69.8-3.13.1-3.12.82.82.83.02.41.9-1.9-2.3-2.3-1.5-1.91.81.61.51.4-1.4-0.2-0.11.50.8
Food consumed during 24 hour testing period0.40.51.6-1.01.1-1.01.30.90.91.00.60.5-0.7-0.6-0.9-0.5-0.50.50.40.30.4-0.30.10.20.70.5
Glucose0.20.30.60.7-0.40.7-0.0-0.6-0.8-0.8-0.40.6-0.70.40.1-0.70.6-0.5-0.7-0.0-0.70.50.40.4-0.60.3
Heart weight0.40.62.50.4-0.70.3-0.4-0.1-0.2-0.40.60.90.3-0.61.0-1.0-0.80.70.50.80.4-0.7-1.1-1.1-1.6-1.0
Delay discount hyperbolic model param0.10.10.4-0.10.3-0.20.10.20.20.3-0.2-0.2-0.10.2-0.30.30.2-0.1-0.2-0.4-0.30.30.30.30.60.4
Intermittent access intake day 1-15 change0.51.12.20.7-0.70.8-1.3-0.6-0.6-0.7-1.4-1.30.51.40.31.51.4-1.3-1.2-1.4-1.11.21.11.10.30.8
Intermittent access intake escalation0.51.12.50.5-0.40.6-1.1-0.4-0.4-0.5-1.4-1.30.41.4-0.01.61.4-1.3-1.3-1.5-1.11.21.31.20.61.0
Intermittent access intake escalation 21.92.23.91.5-1.11.4-1.7-1.6-1.7-1.2-1.9-1.90.71.90.52.01.7-1.7-1.6-1.6-1.51.51.31.20.50.8
Intermitt. access day 1 inactive lever presses0.31.02.5-1.41.4-1.21.41.11.31.10.91.5-1.5-0.8-1.3-1.6-0.30.30.60.70.2-0.30.30.40.80.7
Intermitt. access day 15 inactive lever presses1.53.08.3-2.92.5-2.22.72.92.92.01.11.9-2.0-1.0-2.4-1.6-0.40.40.50.30.2-0.10.80.90.61.4
Intermitt. access escalation Index0.20.30.90.4-0.60.2-0.3-0.3-0.4-0.10.3-0.70.9-0.30.90.6-0.50.50.50.40.8-0.6-0.7-0.7-0.5-0.8
Intermittent access day 1 total infusions0.61.02.0-1.21.3-1.21.31.11.01.01.21.2-1.4-1.2-0.9-1.2-0.70.60.91.20.4-0.7-0.1-0.10.50.3
Intermittent access day 15 total infusions0.20.21.3-0.40.7-0.4-0.00.40.30.5-0.1-0.2-0.60.1-0.60.30.3-0.3-0.2-0.1-0.30.30.70.71.10.8
Intermittent access terminal intake (last 3 days)0.20.20.8-0.50.8-0.60.20.50.30.60.40.3-0.9-0.4-0.5-0.4-0.20.00.20.5-0.2-0.10.30.30.80.5
Intermittent access total infusions0.40.51.9-0.80.9-0.70.70.90.80.60.71.1-1.4-0.6-0.7-1.1-0.20.10.40.7-0.1-0.20.30.30.30.6
Intermittent access day 1 locomotion0.40.51.0-1.00.9-0.90.70.80.80.81.00.6-0.6-1.0-0.6-0.6-0.70.60.80.90.4-0.7-0.4-0.40.6-0.2
Intermittent access day 15 total locomotion0.20.42.6-0.81.0-1.00.50.50.51.10.7-0.3-0.4-0.6-0.70.2-0.40.50.50.50.4-0.5-0.1-0.11.60.2
Intermittent access total locomotion0.91.12.8-1.21.5-1.41.11.10.91.41.20.7-1.1-1.2-1.0-0.8-0.80.81.01.10.6-0.8-0.2-0.21.70.2
Intermittent access standard deviation0.51.02.2-1.11.1-0.70.81.21.30.6-0.30.5-1.20.4-1.40.10.8-0.9-0.8-0.8-1.10.91.41.50.11.5
Left kidney weight0.42.05.0-1.81.6-1.62.01.81.81.31.52.1-1.7-1.5-1.3-2.2-1.01.01.21.40.6-0.8-0.3-0.30.00.2
Right kidney weight0.31.44.1-1.71.4-1.31.61.71.71.00.92.0-1.8-0.8-1.5-1.8-0.40.30.40.6-0.2-0.10.40.4-0.30.7
Cocaine induced anxiety0.40.51.41.0-1.11.1-1.1-1.1-0.7-1.2-0.50.10.40.51.0-0.40.2-0.3-0.10.0-0.30.2-0.2-0.2-1.1-0.5
Post-drug Anxiety1.61.74.21.7-1.51.9-1.5-2.1-1.6-1.8-1.6-0.60.21.60.70.41.3-1.4-1.3-1.0-1.31.30.80.7-0.60.3
Baseline Anxiety0.70.92.40.10.20.30.4-0.3-0.6-0.3-1.0-0.2-0.91.0-0.90.61.2-1.1-1.6-1.0-1.21.31.41.40.21.3
Tail length0.20.73.3-0.60.6-0.20.70.70.7-0.00.11.8-1.6-0.0-0.8-1.30.4-0.5-0.50.0-1.10.50.60.6-1.20.7
Length with tail0.94.09.5-3.12.9-2.52.93.13.12.21.32.7-2.9-1.1-3.0-1.9-0.50.30.10.3-0.30.11.01.10.41.8
Length without tail2.06.617.2-4.13.9-3.33.63.93.83.11.22.5-3.4-1.1-4.1-1.4-0.20.1-0.2-0.1-0.30.31.81.91.52.8
Times rat made contact with spout0.70.82.11.1-0.71.1-0.0-1.2-1.2-1.3-0.70.9-1.00.7-0.0-1.00.9-0.9-1.1-0.1-1.20.80.70.6-1.50.2
Lifetime Intake0.30.42.3-0.50.6-0.30.60.60.50.20.31.2-1.5-0.3-0.6-1.10.1-0.3-0.10.4-0.60.20.60.6-0.20.7
Liver weight, left1.42.36.9-2.01.9-1.82.01.92.11.51.52.6-2.2-1.5-1.6-2.2-0.70.70.91.10.5-0.60.10.2-0.60.5
Liver weight, right3.86.715.6-4.03.6-3.43.73.93.83.02.43.4-3.3-2.2-3.2-2.6-1.41.31.21.30.6-0.80.40.50.21.4
Locomotor activity0.50.72.1-1.51.2-1.11.11.11.31.00.41.1-1.2-0.4-1.4-0.7-0.10.2-0.10.0-0.20.10.40.50.30.8
Locomotor testing distance0.10.10.7-0.60.2-0.30.30.40.60.20.20.8-0.5-0.2-0.4-0.7-0.20.2-0.10.1-0.30.0-0.1-0.1-0.5-0.0
Locomotor testing rearing0.40.82.30.1-0.10.50.2-0.0-0.0-0.7-0.61.4-1.50.7-0.3-1.20.9-1.0-1.0-0.5-1.51.11.01.0-1.10.9
Locomotion in novel chamber0.40.52.1-0.70.6-0.41.00.80.70.20.31.4-1.3-0.3-0.7-1.2-0.2-0.1-0.30.3-0.50.10.30.3-1.10.5
Locomotion in novel chamber post-restriction0.81.26.80.10.30.40.90.00.1-0.70.12.5-2.6-0.1-0.6-2.50.6-0.5-0.70.7-1.30.60.80.8-1.50.9
Fecal boli incidents, locomotor time 10.10.21.30.0-0.20.30.1-0.10.0-0.40.31.0-0.6-0.30.2-1.1-0.20.0-0.10.6-0.2-0.1-0.1-0.1-0.5-0.2
Change in fecal boli incidents, locomotor task0.40.41.40.8-0.80.7-0.7-0.9-1.2-0.7-0.1-0.50.40.10.90.4-0.10.1-0.10.30.1-0.2-0.5-0.5-1.0-0.7
Time >=10cm from walls, locomotor time 10.30.31.41.2-0.80.7-0.7-0.7-0.9-0.7-0.5-0.80.80.40.60.60.3-0.2-0.1-0.2-0.00.1-0.1-0.2-0.0-0.3
Bouts of movement, locomotor time 10.50.61.9-0.1-0.0-0.4-0.30.40.60.30.90.50.6-1.00.9-0.7-1.10.91.40.91.0-1.1-0.8-0.8-0.0-0.7
Total resting periods, locomotor time 10.50.61.9-0.0-0.2-0.3-0.60.10.40.30.80.01.0-0.81.1-0.2-1.00.91.40.71.1-1.0-0.9-0.90.2-0.9
Rest time, locomotor task time 10.40.62.60.6-0.60.1-1.3-0.6-0.40.0-0.0-1.21.60.01.21.3-0.40.30.4-0.20.8-0.5-0.6-0.60.3-0.7
Distance moved, locomotor task time 10.81.13.5-1.61.3-1.11.91.31.20.91.01.3-1.5-1.0-1.4-1.5-0.50.70.71.00.2-0.5-0.1-0.00.60.4
Vertical activity count, locomotor time 10.71.76.0-2.01.8-1.42.51.81.81.30.61.3-1.7-0.5-2.4-1.1-0.10.2-0.10.2-0.30.20.70.80.81.2
Time >=10cm from walls, locomotor time 20.10.20.40.3-0.30.1-0.5-0.0-0.2-0.10.3-0.20.5-0.30.50.1-0.50.30.40.40.5-0.5-0.6-0.60.0-0.6
Bouts of movement, locomotor time 20.10.10.30.3-0.40.3-0.2-0.00.5-0.3-0.40.30.50.4-0.1-0.20.5-0.5-0.3-0.5-0.20.30.30.3-0.00.1
Total resting periods, locomotor time 20.10.20.40.6-0.60.5-0.5-0.30.2-0.5-0.60.00.70.60.20.00.6-0.5-0.3-0.6-0.20.40.30.3-0.10.0
Rest time, locomotor task time 21.82.24.71.4-1.31.4-1.9-1.3-1.1-1.3-2.1-1.81.52.00.72.11.7-1.6-1.5-2.2-0.91.51.11.1-0.20.6
Distance moved, locomotor task time 21.61.94.5-2.11.8-1.62.11.81.71.51.51.8-1.9-1.4-1.6-1.7-1.01.00.91.20.3-0.7-0.2-0.10.80.5
Vertical activity count, locomotor time 21.82.57.1-2.32.1-1.82.72.12.01.61.42.2-2.4-1.3-2.1-2.0-0.80.70.61.10.0-0.50.20.20.70.9
Light reinforcement 10.30.71.50.2-0.10.4-0.2-0.3-0.2-0.3-1.1-0.5-0.21.1-0.60.80.8-1.2-1.1-1.2-0.81.11.21.20.81.1
Light reinforcement 20.81.34.6-1.31.5-1.22.01.11.11.20.20.9-1.9-0.1-2.1-0.40.1-0.2-0.4-0.2-0.30.51.11.21.31.4
Bone: marrow area0.71.44.6-1.41.5-1.71.11.11.11.91.3-0.3-0.0-1.3-1.10.3-1.31.31.20.81.4-1.2-0.7-0.62.1-0.2
Bone: maximum diameter2.85.211.4-3.43.3-3.32.93.03.03.32.51.7-1.9-2.4-2.6-1.3-2.12.01.61.51.5-1.5-0.2-0.12.01.0
Bone: maximum force3.35.912.8-3.53.6-3.43.33.23.13.32.62.2-2.3-2.5-2.8-1.9-2.01.91.71.71.5-1.5-0.00.11.91.1
Bone: maximum moment3.35.812.7-3.53.6-3.43.33.23.13.42.62.1-2.3-2.5-2.7-1.8-2.02.01.71.61.5-1.5-0.10.11.91.0
Mean time between licks in bursts1.33.38.20.5-0.3-0.40.3-0.5-0.60.32.30.70.7-2.31.1-1.5-2.42.42.22.92.1-2.6-2.8-2.8-0.6-2.6
Mean num. licks in bursts0.30.41.3-1.00.6-0.60.91.11.00.6-0.1-0.2-0.10.2-1.20.20.10.0-0.2-0.6-0.00.30.60.60.70.8
Cd content in liver0.30.31.10.5-0.30.1-0.6-0.5-0.60.00.1-1.00.8-0.10.90.8-0.40.30.40.20.7-0.4-0.5-0.50.5-0.6
Co content in liver0.40.41.1-0.10.30.1-0.10.20.1-0.0-0.8-0.5-0.20.8-0.30.90.8-0.8-0.9-1.0-0.90.90.80.90.50.9
Cu content in liver0.10.10.40.40.10.20.2-0.2-0.4-0.20.10.3-0.2-0.10.2-0.6-0.10.20.30.40.2-0.1-0.5-0.5-0.1-0.3
Fe content in liver0.20.30.8-0.20.30.00.10.10.2-0.0-0.50.0-0.40.6-0.80.40.6-0.6-0.9-0.7-0.90.70.70.7-0.10.7
K content in liver0.10.10.20.10.3-0.00.1-0.2-0.1-0.00.30.4-0.1-0.30.1-0.4-0.30.30.20.40.2-0.2-0.3-0.3-0.3-0.2
Mg content in liver0.70.72.0-1.01.1-0.60.80.90.90.6-0.30.6-1.20.4-1.3-0.10.6-0.6-0.7-0.8-0.70.91.21.20.41.4
Mn content in liver0.00.00.1-0.10.10.00.30.20.3-0.10.00.30.0-0.0-0.2-0.3-0.00.00.00.00.00.00.10.10.30.2
Na content in liver0.10.20.40.00.00.2-0.3-0.1-0.0-0.2-0.5-0.1-0.10.5-0.20.30.4-0.4-0.6-0.6-0.60.60.50.50.10.5
Rb content in liver0.50.62.0-0.70.9-0.50.60.50.40.6-0.5-0.2-0.90.6-1.40.60.7-0.7-0.8-0.8-0.50.91.01.01.01.2
Se content in liver0.30.31.0-0.80.6-0.60.71.01.00.50.50.9-0.4-0.5-0.5-0.8-0.40.50.50.30.4-0.3-0.1-0.00.10.3
Sr content in liver0.70.61.80.7-0.60.3-0.8-0.5-0.5-0.20.4-0.61.2-0.51.40.3-0.70.70.90.60.8-0.9-1.0-1.1-0.0-1.2
Zn content in liver0.40.51.4-1.11.2-1.11.01.00.91.10.60.3-0.6-0.6-0.7-0.2-0.60.70.40.20.6-0.3-0.10.00.70.4
Bone: minimum diameter1.93.46.5-2.32.3-2.52.02.12.12.62.30.9-0.7-2.3-1.4-0.9-2.12.21.91.71.8-1.8-0.9-0.81.9-0.1
Time in familiar zone, hab. session 10.10.10.40.4-0.30.50.0-0.3-0.4-0.5-0.5-0.30.10.5-0.10.20.6-0.5-0.4-0.3-0.50.40.30.20.10.1
Time in novel zone, hab. session 10.20.21.1-0.60.6-0.6-0.10.50.50.7-0.1-0.6-0.00.1-0.31.1-0.00.0-0.2-0.60.10.20.50.50.60.7
Total zone transitions, hab. session 10.60.82.1-0.30.20.1-0.30.40.5-0.0-1.1-0.6-0.11.1-0.41.01.2-1.1-1.0-1.5-1.01.21.31.30.51.2
Total locomotion distance, hab. session 13.34.611.7-1.10.7-0.00.01.11.20.2-2.5-1.1-0.72.5-1.82.22.7-2.6-2.6-3.4-2.42.93.33.31.23.2
Locomotion velocity, hab. session 12.63.79.3-0.70.40.3-0.20.91.0-0.2-2.3-0.7-0.72.4-1.41.72.5-2.5-2.4-3.0-2.42.72.92.90.52.7
Time in familiar zone, hab. session 20.10.10.7-0.2-0.1-0.00.00.10.20.1-0.2-0.80.60.2-0.30.8-0.0-0.1-0.2-0.40.20.10.00.00.6-0.0
Time in novel zone, hab. session 20.20.20.9-0.10.3-0.30.20.10.10.20.51.0-0.7-0.50.1-0.8-0.30.40.30.60.1-0.3-0.2-0.2-0.50.0
Total zone transitions, hab. session 22.02.65.41.3-1.51.9-1.4-1.0-1.0-2.0-2.2-0.20.12.20.70.42.3-2.2-1.9-1.9-2.22.11.51.4-1.50.9
Total locomotion distance, hab. session 24.55.912.01.7-1.92.5-2.0-1.4-1.3-2.5-3.5-1.30.53.50.51.93.4-3.3-3.1-3.4-3.13.22.52.4-1.01.6
Locomotion velocity, hab. session 23.95.210.61.6-1.82.3-2.0-1.3-1.2-2.3-3.3-1.20.43.30.61.73.2-3.1-2.8-3.1-3.03.02.32.2-0.91.5
Novel to familiar place preference ratio0.91.03.20.7-0.71.1-0.3-0.6-0.5-1.3-0.91.2-0.81.0-0.1-1.01.2-1.2-1.2-0.6-1.51.21.01.0-1.80.6
Novelty place preference0.60.62.30.4-0.40.8-0.1-0.4-0.3-1.0-0.51.3-0.90.5-0.1-1.20.8-0.8-0.8-0.2-1.10.80.70.7-1.50.5
Time in novel zone, NPP test0.30.31.30.2-0.30.50.1-0.1-0.1-0.7-0.31.1-0.70.4-0.2-1.00.6-0.6-0.6-0.2-0.80.60.60.6-1.10.4
Total zone transitions, NPP test1.42.04.80.6-0.71.2-0.6-0.4-0.3-1.3-1.9-0.1-0.42.0-0.30.52.2-2.1-1.9-1.9-2.02.11.91.8-0.71.3
Total locomotion distance, NPP test4.66.213.61.1-1.32.1-1.4-1.0-0.9-2.0-3.6-1.30.13.6-0.52.03.6-3.5-3.5-3.7-3.33.53.13.0-0.52.2
Locomotion velocity, NPP test5.37.415.81.2-1.42.3-1.5-1.0-1.0-2.2-3.8-1.2-0.23.9-0.62.04.0-3.9-3.8-4.0-3.73.83.43.3-0.82.4
Intraocular pressure0.00.10.60.30.00.1-0.2-0.3-0.3-0.10.10.4-0.4-0.10.4-0.1-0.10.0-0.10.1-0.30.00.10.1-0.70.2
Delta distance traveled before/after self-admin0.80.92.7-1.11.3-1.01.61.30.80.80.61.3-1.7-0.5-1.4-1.3-0.1-0.00.10.4-0.40.10.50.50.60.8
Delta ambulatory time before/after self-admin0.40.51.8-0.60.9-0.51.10.80.50.30.21.0-1.3-0.1-1.1-1.00.2-0.3-0.20.2-0.60.30.60.60.40.7
Parametrial fat weight1.84.39.5-3.13.1-3.02.92.72.63.02.11.7-2.0-2.0-2.6-1.3-1.61.61.41.21.1-1.1-0.00.11.90.9
Pavlov. Cond. lever latency0.40.52.0-1.11.2-0.90.60.91.00.90.51.2-1.4-0.4-0.7-0.6-0.10.20.00.1-0.20.10.40.4-0.10.8
Pavlov. Cond. magazine entry latency0.60.82.31.5-1.51.5-0.7-1.5-1.4-1.5-0.8-0.50.70.70.8-0.00.7-0.7-0.5-0.1-0.50.3-0.2-0.2-0.6-0.6
Pavlov. Cond. change in total contacts0.10.10.30.4-0.60.50.1-0.5-0.3-0.5-0.2-0.40.50.2-0.2-0.00.1-0.1-0.10.10.1-0.1-0.1-0.10.2-0.3
Pavlov. Cond. index score0.91.13.21.8-1.81.7-0.9-1.6-1.6-1.7-0.8-0.91.30.81.00.20.6-0.6-0.4-0.1-0.30.2-0.3-0.4-0.6-0.9
Pavlov. Cond. latency score0.91.23.51.9-1.81.7-1.0-1.7-1.8-1.6-0.7-1.01.40.71.20.20.4-0.5-0.20.0-0.10.0-0.5-0.6-0.5-1.1
Pavlov. Cond. lever contacts0.81.03.01.5-1.51.3-1.0-1.4-1.5-1.2-0.5-1.41.70.41.10.70.0-0.10.00.00.2-0.3-0.7-0.8-0.2-1.1
Pavlov. Cond. magazine entry number0.60.82.3-1.51.5-1.40.71.51.41.40.80.8-0.9-0.7-0.7-0.2-0.60.60.50.20.4-0.30.20.30.50.6
Pavlov. Cond. intertrial magazine entries0.50.61.8-0.70.3-0.70.00.60.60.90.5-1.31.2-0.5-0.11.3-0.80.80.70.10.9-0.8-0.8-0.71.1-0.7
Pavlov. Cond. lever-magazine prob. diff.0.81.03.11.8-1.71.6-0.9-1.6-1.6-1.6-0.8-0.81.20.71.00.10.6-0.6-0.4-0.1-0.30.2-0.3-0.4-0.6-0.8
Pavlov. Cond. response bias0.60.71.61.2-1.31.3-0.6-1.1-1.0-1.2-1.0-1.00.91.00.20.70.8-0.8-0.8-0.6-0.60.60.30.2-0.2-0.2
Pavlov. Cond. lever latency0.50.61.9-0.40.2-0.70.20.40.40.90.8-0.90.9-0.80.20.8-1.11.01.00.51.4-1.0-0.8-0.81.0-0.7
Pavlov. Cond. magazine entry latency0.20.30.8-0.20.20.10.20.30.2-0.2-0.50.4-0.80.5-0.4-0.10.7-0.7-0.8-0.6-0.90.70.80.8-0.20.7
Pavlov. Cond. change in total contacts0.60.92.21.0-0.71.1-1.2-1.1-1.0-1.1-1.20.1-0.31.20.50.11.2-1.1-1.3-0.9-1.51.10.70.7-1.00.4
Pavlov. Cond. index score0.40.51.50.2-0.10.5-0.5-0.2-0.2-0.6-0.90.2-0.50.9-0.10.11.0-1.0-1.0-0.9-1.21.00.90.9-0.40.7
Pavlov. Cond. latency score0.40.51.30.6-0.40.7-0.6-0.6-0.5-0.8-0.90.2-0.30.90.2-0.01.0-0.9-1.0-0.7-1.20.90.60.6-0.50.4
Pavlov. Cond. lever contacts0.40.61.70.4-0.20.7-0.2-0.4-0.3-0.9-0.61.1-1.00.6-0.1-1.00.9-0.9-0.9-0.4-1.30.90.70.7-1.20.5
Pavlov. Cond. magazine entry number0.30.41.2-0.10.0-0.40.40.10.10.50.7-0.40.7-0.7-0.00.1-0.90.90.90.71.1-0.9-0.8-0.80.5-0.7
Pavlov. Cond. intertrial magazine entries0.60.92.20.6-0.70.1-0.1-0.6-0.6-0.10.9-0.31.1-0.90.5-0.3-1.21.21.11.21.2-1.3-1.5-1.5-0.1-1.4
Pavlov. Cond. lever-magazine prob. diff.0.40.61.70.5-0.40.7-0.7-0.5-0.5-0.8-1.00.0-0.31.00.10.21.1-1.1-1.1-0.9-1.31.10.80.8-0.50.6
Pavlov. Cond. response bias0.71.03.00.1-0.00.6-0.2-0.1-0.1-0.7-1.00.8-1.11.1-0.4-0.41.4-1.3-1.4-1.0-1.71.41.31.3-0.91.1
Time in closed arm before self-admin0.50.61.50.2-0.1-0.2-0.2-0.1-0.50.30.7-0.60.9-0.70.60.3-1.10.91.10.81.2-1.1-1.0-1.01.0-1.0
Time in closed arm after self-admin1.11.22.60.2-0.2-0.3-0.7-0.3-0.50.41.0-0.91.4-1.01.20.6-1.41.31.61.11.6-1.5-1.6-1.60.8-1.5
Time in open arm before self-admin0.10.21.0-0.10.1-0.00.30.20.4-0.10.21.0-0.6-0.20.1-1.00.00.1-0.00.2-0.20.0-0.0-0.0-0.90.1
Time in open arm after self-admin0.20.20.70.4-0.40.50.2-0.3-0.1-0.7-0.20.8-0.70.2-0.1-0.80.4-0.4-0.60.0-0.60.40.20.2-0.80.0
Bone: periosteal estimation1.73.67.5-2.62.6-2.72.22.32.32.72.21.2-1.2-2.2-1.9-1.0-1.91.91.71.51.6-1.6-0.7-0.51.80.2
Bone: periosteal perimeter2.34.07.0-2.52.6-2.72.32.22.22.62.61.8-1.5-2.5-1.5-1.8-2.22.22.02.01.6-1.8-0.9-0.81.50.1
Bone: post-yield work1.82.64.6-1.81.9-2.02.01.51.52.02.11.3-1.1-2.1-1.2-1.5-1.81.81.71.91.5-1.6-0.9-0.81.2-0.2
Progressive ratio test 1 active lever presses0.80.94.7-0.60.40.10.60.70.8-0.40.12.2-1.9-0.0-0.5-1.90.3-0.6-0.50.2-1.20.60.70.8-1.70.8
Progressive ratio test 1 breakpoint0.81.05.0-0.60.40.10.60.70.8-0.40.02.2-2.00.0-0.5-2.00.4-0.7-0.60.2-1.30.70.80.8-1.80.9
Progressive ratio test 1 inactive lever presses0.30.42.0-0.60.6-0.50.90.50.60.30.71.4-1.2-0.7-0.4-1.4-0.40.20.50.8-0.0-0.3-0.1-0.1-0.1-0.0
Progressive ratio test 2 active lever presses0.50.62.8-0.50.6-0.10.30.20.3-0.0-0.11.2-1.70.2-0.8-1.10.5-0.6-0.50.0-1.00.61.01.00.11.1
Progressive ratio test 2 breakpoint0.50.62.8-0.50.7-0.10.40.30.40.0-0.21.2-1.70.2-0.8-1.00.6-0.7-0.6-0.1-1.00.71.11.10.21.2
Progressive ratio test 2 inactive lever presses0.40.62.7-0.70.8-0.40.70.60.60.30.31.6-1.6-0.3-0.8-1.50.1-0.3-0.10.4-0.50.20.60.6-0.00.8
Incentive Sensitization - Responses0.20.31.7-0.70.7-0.60.30.30.40.60.10.1-0.6-0.1-0.7-0.00.3-0.10.0-0.0-0.00.10.50.51.30.7
Incentive Sensitization - Breakpoint0.20.31.7-0.60.7-0.50.30.30.40.6-0.0-0.1-0.60.1-0.80.10.5-0.3-0.2-0.2-0.20.30.70.71.30.8
Sum of active levers in priming session hrs 5-64.13.88.4-1.31.8-2.12.11.31.02.02.81.5-1.1-2.8-0.6-1.9-2.52.52.52.92.0-2.4-1.7-1.61.0-1.0
Progressive ratio0.10.21.2-0.10.1-0.1-0.0-0.1-0.00.2-0.4-0.90.30.4-0.41.10.2-0.4-0.4-0.6-0.00.30.30.30.60.2
Food seeking constrained by brief footshock0.50.61.8-0.81.2-1.01.30.60.51.00.80.6-1.1-0.8-1.0-0.7-0.70.60.40.80.4-0.4-0.1-0.01.10.4
Seeking ratio, punishment vs. effort0.30.41.6-0.50.5-0.50.80.60.50.30.71.2-0.8-0.7-0.2-1.3-0.40.60.50.80.2-0.4-0.2-0.2-0.20.1
Retroperitoneal fat weight1.87.715.1-3.93.5-3.83.53.73.73.73.32.5-1.8-3.2-2.4-2.2-2.72.82.82.22.3-2.3-1.1-1.01.30.0
Reaction time number correct0.20.31.51.0-0.80.8-0.7-1.2-0.9-0.7-0.5-0.40.40.50.40.40.5-0.3-0.5-0.2-0.40.20.10.1-0.6-0.2
Reaction time mean minus median0.10.20.70.2-0.30.1-0.6-0.00.0-0.10.2-0.50.8-0.20.80.3-0.30.20.60.20.4-0.4-0.6-0.60.6-0.7
Reaction time mean minus median AUC0.00.10.6-0.10.1-0.1-0.30.10.20.1-0.2-0.40.30.20.10.50.2-0.3-0.1-0.4-0.20.20.20.20.80.2
Reaction time num false alarms0.10.10.3-0.30.2-0.20.00.40.40.2-0.2-0.0-0.10.2-0.20.10.4-0.4-0.3-0.4-0.00.30.50.50.50.3
Reaction time num false alarms AUC0.00.00.1-0.1-0.0-0.1-0.10.20.30.00.10.30.0-0.10.2-0.30.1-0.10.10.10.3-0.10.00.00.3-0.2
Reaction time trials correct on left0.20.31.51.0-0.80.8-0.7-1.2-0.9-0.7-0.5-0.40.40.50.40.40.5-0.3-0.5-0.2-0.40.20.10.1-0.6-0.2
Reaction time trials on left0.20.31.41.0-0.80.7-0.7-1.2-0.9-0.6-0.4-0.40.50.40.40.40.4-0.2-0.4-0.2-0.30.20.00.0-0.5-0.2
Reaction time mean1.01.65.4-1.00.8-1.30.31.01.01.51.2-1.11.2-1.20.20.8-1.41.51.80.81.9-1.5-1.2-1.22.3-0.9
Reaction time mean AUC1.01.66.3-0.70.6-1.1-0.00.70.81.41.0-1.61.6-1.00.41.3-1.31.41.60.51.9-1.4-1.2-1.12.5-0.9
Median of all reaction times1.62.37.8-1.41.2-1.80.71.21.32.01.5-1.31.3-1.5-0.21.0-1.61.82.00.92.3-1.7-1.3-1.22.8-0.9
Reaction time omissions0.81.22.60.2-0.4-0.2-0.6-0.2-0.20.30.9-1.11.6-0.91.10.6-1.21.31.51.01.5-1.4-1.6-1.60.8-1.5
Reaction time false alarm rate0.00.10.4-0.40.2-0.20.00.70.60.2-0.00.3-0.10.0-0.0-0.20.1-0.3-0.0-0.20.10.10.20.20.30.1
Reaction time premature initiation rate0.81.12.60.2-0.4-0.2-0.2-0.1-0.00.11.20.50.6-1.30.8-1.1-1.21.21.41.51.3-1.5-1.6-1.6-0.5-1.5
Reaction time premature initiations0.50.92.30.7-0.80.2-0.6-0.7-0.5-0.20.90.10.9-0.91.1-0.5-0.91.01.11.21.0-1.2-1.4-1.5-0.6-1.5
Std. dev. reaction times0.20.32.2-0.50.3-0.5-0.20.60.50.60.3-0.90.9-0.30.30.8-0.40.40.6-0.00.7-0.4-0.4-0.41.5-0.3
Reaction time trials completed0.20.31.41.0-0.80.7-0.7-1.2-0.9-0.6-0.4-0.40.50.40.40.40.4-0.2-0.4-0.2-0.30.20.00.0-0.5-0.2
Reaction time trials AUC0.10.21.20.9-0.70.6-0.7-1.1-0.8-0.5-0.3-0.40.40.30.40.40.4-0.2-0.3-0.1-0.30.10.00.0-0.4-0.2
Run reversals in cocaine runway, females0.80.82.00.5-0.40.7-0.5-0.4-0.5-0.7-1.2-0.4-0.21.2-0.30.71.3-1.2-1.3-1.2-1.41.31.11.1-0.20.8
Run reversals in cocaine runway, males0.20.20.6-0.20.3-0.10.40.10.10.0-0.20.3-0.70.2-0.5-0.30.3-0.3-0.3-0.1-0.30.40.70.70.60.8
Latency to leave start box in cocaine runway0.50.61.60.2-0.0-0.3-0.1-0.3-0.30.40.8-0.50.8-0.80.50.2-1.01.01.10.91.3-1.1-1.0-1.01.0-0.8
Latency to leave start box in cocaine runway, F0.30.31.1-0.70.8-0.60.80.50.50.60.30.5-0.9-0.3-0.9-0.4-0.20.20.10.20.1-0.00.50.61.00.8
Latency to leave start box in cocaine runway, M2.42.37.21.5-1.60.8-1.8-1.5-1.5-0.60.3-1.92.7-0.42.21.3-1.01.01.10.61.6-1.3-2.0-2.0-0.3-2.2
Std. dev. time between licks in bursts1.62.27.1-1.31.6-1.41.91.21.21.21.92.7-1.9-1.8-1.2-2.7-1.21.21.11.90.7-1.2-0.5-0.5-0.3-0.1
Total sessions with >9 infusions0.70.83.21.3-1.31.4-1.3-1.2-1.1-1.5-0.30.5-0.00.31.3-0.60.2-0.5-0.40.4-0.60.2-0.3-0.4-1.8-0.7
Short access day 1 total inactive lever presses0.81.12.8-0.40.30.20.50.60.7-0.5-0.61.6-1.70.6-0.8-1.01.2-1.2-1.3-0.7-1.61.21.31.3-1.21.1
Short access day 10 total inactive lever presses0.20.41.4-1.00.7-0.71.01.01.20.60.41.0-0.8-0.3-0.8-0.80.00.00.20.10.10.00.30.3-0.30.4
Short access day 1 total infusions0.71.04.70.8-0.71.00.0-0.6-0.5-1.3-0.12.0-1.40.10.5-2.00.4-0.7-0.60.5-1.20.50.40.3-2.20.1
Short access day 10 total infusions0.20.21.1-0.50.6-0.50.60.70.50.30.50.9-1.0-0.4-0.4-0.7-0.20.00.10.4-0.2-0.10.30.3-0.20.4
Short access total infusions0.20.31.8-0.10.10.10.50.30.1-0.30.31.3-1.3-0.3-0.1-1.3-0.1-0.2-0.10.5-0.60.10.30.3-1.00.3
Short access day 1 locomotion0.60.84.10.8-0.70.9-0.5-0.7-0.5-1.20.21.8-1.0-0.20.8-2.00.0-0.2-0.00.9-0.70.0-0.2-0.3-1.8-0.5
Short access day 10 total locomotion0.30.61.70.7-0.60.3-0.5-0.8-0.7-0.30.70.10.4-0.71.1-0.4-0.80.80.81.20.7-1.0-1.2-1.2-0.3-1.3
Short access total locomotion0.70.82.10.9-0.80.5-0.9-0.8-0.7-0.60.80.40.4-0.81.4-0.8-0.90.70.91.40.6-1.0-1.3-1.3-0.6-1.4
One hour access (0.3 mA shock)0.60.72.5-1.00.9-0.50.70.91.20.40.31.6-1.6-0.3-0.8-1.50.2-0.10.00.3-0.50.20.70.7-0.11.0
Compulsive drug intake1.82.14.6-1.81.9-1.92.11.91.91.81.61.2-0.9-1.5-1.3-1.3-1.31.51.41.11.2-1.0-0.5-0.41.90.2
One hour access (shock baseline)0.40.62.30.5-0.60.9-0.8-0.5-0.4-1.0-0.70.6-0.60.70.3-0.60.7-1.0-0.8-0.4-1.10.80.70.7-1.50.5
Social response proportion0.60.73.4-0.70.6-0.51.20.70.90.30.81.8-1.5-0.7-0.8-1.8-0.10.30.10.8-0.1-0.2-0.00.1-0.80.5
Social responses0.20.30.70.8-0.80.8-0.3-0.8-0.5-0.9-0.40.4-0.20.40.3-0.60.5-0.6-0.4-0.1-0.50.30.20.1-0.8-0.0
Social time0.91.23.3-1.41.3-1.21.61.21.31.00.81.8-1.8-0.8-1.3-1.8-0.50.20.20.60.1-0.20.50.50.41.0
Soleus weight0.20.71.2-0.80.8-0.40.51.10.90.3-0.31.0-1.10.4-1.1-0.30.8-0.7-0.9-0.8-1.00.90.91.0-0.51.1
Bone: stiffness1.93.16.1-2.42.5-2.32.52.22.22.21.92.1-2.0-1.8-1.9-1.9-1.41.31.31.41.0-1.00.10.21.00.9
Tibialis anterior weight0.20.62.2-0.60.7-0.30.80.50.50.2-0.21.1-1.50.3-1.1-0.80.8-0.6-0.7-0.3-0.80.81.11.1-0.11.2
Time to tail flick, vehicle, before self-admin1.81.84.6-2.12.0-1.82.02.02.11.71.31.6-1.6-1.2-1.4-1.2-0.80.90.70.80.4-0.50.10.20.40.8
Time to tail flick, vehicle, after self-admin1.01.32.6-0.91.1-1.10.81.31.31.01.51.3-0.7-1.50.2-1.5-1.41.41.61.50.9-1.2-0.9-0.80.5-0.4
Time to tail flick, test, before self-admin0.30.41.0-0.40.4-0.60.40.30.50.70.3-0.91.0-0.3-0.60.8-0.60.80.4-0.10.7-0.5-0.4-0.40.9-0.1
Time to tail flick, test, after self-admin2.93.05.3-2.11.7-1.91.92.01.81.82.32.1-1.3-2.2-0.6-2.3-1.81.91.82.01.4-1.7-1.0-0.90.9-0.3
Delta time to tail flick, vehicle, before/after SA0.60.51.70.6-0.50.3-0.8-0.4-0.4-0.20.4-0.30.9-0.51.3-0.2-0.70.71.10.80.8-0.8-1.0-1.00.2-1.1
Delta time to tail flick, test, before/after SA1.91.97.7-1.91.5-1.31.61.71.61.01.32.8-2.6-1.2-0.8-2.6-0.50.30.61.3-0.0-0.30.30.30.20.6
Tibia length0.92.65.2-2.32.1-2.31.62.12.12.31.90.8-0.5-1.8-1.3-0.7-1.71.71.71.21.7-1.4-0.7-0.61.40.1
Ambulatory time before self-admin1.11.74.41.9-2.11.8-1.4-2.1-2.1-1.9-0.20.00.60.21.8-0.40.00.0-0.20.8-0.1-0.3-1.0-1.1-2.1-1.5
Ambulatory time after self-admin0.50.63.60.5-0.20.50.7-0.3-1.0-0.80.41.6-1.6-0.40.0-1.9-0.1-0.0-0.11.2-0.5-0.1-0.2-0.2-0.9-0.3
Bone: tissue strength1.92.04.3-2.12.0-2.02.12.01.91.91.31.6-1.8-1.3-1.7-1.2-0.81.00.70.80.4-0.50.20.30.80.9
Total heroin consumption0.20.21.40.6-0.10.1-0.3-0.6-1.2-0.10.4-0.1-0.3-0.40.6-0.1-0.30.20.60.90.4-0.5-0.5-0.50.3-0.6
Bone: trabecular number1.52.55.8-2.22.1-1.92.22.22.31.61.12.3-2.4-1.0-1.8-2.1-0.30.40.60.6-0.1-0.10.91.00.81.6
Bone: trabecular spacing0.50.74.20.5-0.60.5-1.1-0.5-0.5-0.3-0.9-1.71.30.90.62.00.5-0.5-0.7-1.2-0.40.50.20.2-0.2-0.0
Bone: trabecular thickness2.02.54.6-1.51.4-1.71.61.41.51.62.11.4-0.6-2.1-0.7-1.8-1.91.92.02.01.6-1.8-1.3-1.20.8-0.7
Bone: trabecular tissue density0.30.51.71.0-1.21.0-1.0-0.8-0.9-1.0-0.6-0.30.70.51.10.10.3-0.3-0.4-0.3-0.20.3-0.3-0.3-1.3-0.5
Water consumed over 24 hours1.01.43.20.10.30.50.8-0.2-0.2-0.6-1.01.1-1.81.1-1.2-0.81.5-1.5-1.5-0.8-1.71.51.71.7-0.71.6
Number of responses in last shaping day0.91.05.2-0.60.5-0.40.80.90.90.11.02.2-1.4-1.0-0.3-2.3-0.70.40.61.2-0.1-0.5-0.4-0.4-1.6-0.2