Bptf

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_001127535.2 0.03 0.02 9.2e-04 0.01 0.02 0.01 0.01 2.3e-03 7.4e-04 2.8e-03 1.9e-03
2 Brain intron excision ratio chr10_92498031_92499591 0.04 0.03 3.0e-03 0.01 0.01 0.01 0.01 3.7e-02 1.9e-02 6.9e-02 4.1e-02
3 Brain intron excision ratio chr10_92498031_92499168 0.04 0.03 2.0e-03 0 0.02 0.01 0.01 2.2e-01 1.2e-02 5.4e-02 4.2e-02
4 Brain mRNA stability Bptf 0.12 0.06 8.9e-11 0.12 0.12 0.11 0.11 7.6e-11 4.8e-11 1.8e-10 9.5e-11
5 Brain gene expression Bptf 0.05 0.03 2.0e-04 0.02 0.02 0.02 0.02 8.7e-03 2.3e-03 2.5e-03 3.6e-03
6 BLA mRNA stability Bptf 0.04 0.03 9.6e-03 0.01 0.03 0.01 0.02 8.6e-02 1.1e-02 4.9e-02 2.7e-02
7 NAcc mRNA stability Bptf 0.04 0.02 5.7e-06 0.05 0.04 0.04 0.05 5.7e-08 7.9e-07 3.6e-06 1.0e-07
8 PL mRNA stability Bptf 0.06 0.03 9.1e-08 0.09 0.07 0.08 0.09 1.6e-09 1.7e-08 4.3e-09 1.6e-09
9 pVTA gene expression Bptf 0.05 0.03 1.7e-03 0.03 0.03 0.02 0.03 1.5e-03 1.6e-03 1.7e-02 3.8e-03
10 pVTA mRNA stability Bptf 0.04 0.03 8.0e-03 0.01 0 0 0 9.7e-02 2.2e-01 1.2e-01 1.1e-01
11 Adipose alternative TSS XM_063269218.1 0.02 0.01 3.8e-03 0.02 0.01 0.02 0.02 1.4e-03 1.3e-02 3.3e-03 3.9e-03
12 NAcc alternative polyA XM_063269218.1 0.03 0.02 7.8e-04 0.02 0.02 0.01 0.01 1.0e-03 1.2e-03 9.7e-03 2.2e-03
13 NAcc intron excision ratio chr10_92510107_92510319 0.01 0.01 6.5e-03 0.01 0.01 0.01 0.01 7.6e-03 7.1e-03 3.9e-03 6.1e-03
14 pVTA isoform ratio NM_001127535.2 0.04 0.02 5.4e-03 0.03 0.03 0.03 0.02 1.4e-03 3.0e-03 1.1e-03 4.7e-03
15 IC mRNA stability Bptf 0.07 0.04 9.3e-03 0.03 0.04 0.03 0.03 1.9e-02 1.0e-02 3.0e-02 3.1e-02
16 Adipose alternative polyA XM_063269218.1 0.02 0.01 7.6e-03 0.01 0.02 0.01 0.01 1.5e-02 2.6e-03 6.0e-02 1.8e-02
17 Adipose alternative polyA NM_001127535.2 0.02 0.01 4.7e-03 0.01 0.02 0.01 0.01 9.5e-03 1.5e-03 4.1e-02 1.4e-02
18 Adipose isoform ratio NM_001127535.2 0.02 0.01 5.7e-03 0.01 0.02 0.01 0.01 8.3e-03 2.7e-03 3.7e-02 1.5e-02
19 Adipose alternative TSS NM_001127535.2 0.02 0.01 4.7e-03 0.02 0.01 0.02 0.02 2.7e-03 1.0e-02 5.6e-03 3.5e-03
20 BLA gene expression Bptf 0.06 0.04 3.6e-03 0.04 0.03 0.01 0.03 3.5e-03 1.8e-02 1.4e-01 1.7e-02
21 Liver intron excision ratio chr10_92482778_92487249 0.04 0.03 4.0e-05 0.03 0.03 0.02 0.03 2.2e-04 1.8e-04 2.3e-03 7.1e-04
22 Liver intron excision ratio chr10_92483523_92487249 0.06 0.04 1.3e-06 0.04 0.04 0.02 0.03 1.2e-05 4.2e-05 3.6e-03 1.3e-04
23 NAcc isoform ratio XM_063269220.1 0.02 0.01 1.6e-03 0.01 0.01 0.01 0.01 1.2e-02 7.8e-03 2.2e-02 1.4e-02
24 PL gene expression Bptf 0.04 0.02 4.9e-03 -0 0.01 0 0 7.7e-01 7.6e-03 3.7e-01 1.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.40.72.50.31.1-1.10.9-0.90.90.60.80.40.9-0.4-0.2-0.7-1.61.1-0.90.90.90.2-1.1-0.30.40.6-1.1
Area under the delay curve0.20.21.6-0.60.4-0.5-0.2-0.5-0.3-0.6-0.5-0.70.3-0.10.30.7-0.80.5-0.10.1-0.00.20.20.10.2-0.2-1.3
BMI with tail1.13.818.73.73.3-3.41.5-4.32.41.41.81.42.1-1.8-0.9-0.9-1.12.10.1-0.1-0.0-0.1-0.42.1-0.0-0.1-1.4
BMI without tail2.57.531.64.94.5-4.62.5-5.63.42.42.52.23.0-3.0-2.1-1.6-2.13.1-0.40.20.40.4-0.62.40.20.0-2.0
Body weight2.711.932.05.04.9-4.93.7-5.74.33.63.63.34.0-4.0-3.2-2.8-3.54.1-2.01.91.91.9-2.01.01.81.1-3.0
Weight adjusted by age0.40.51.3-0.9-0.50.4-0.80.6-1.1-1.1-1.1-1.0-0.40.60.71.00.2-0.70.7-0.7-0.7-0.40.80.3-0.3-0.80.0
Bone surface3.36.011.22.12.5-2.33.3-1.82.93.03.22.62.2-2.1-2.1-2.8-3.42.7-2.72.72.61.6-2.4-1.21.71.7-1.6
Bone volume2.64.710.21.82.5-2.42.8-2.02.52.42.62.12.1-1.9-1.7-2.2-3.22.5-2.32.32.21.4-2.2-0.81.51.3-1.9
Breakpoint value in progressive ratio session0.70.83.50.8-0.70.8-0.20.6-0.6-0.1-0.0-0.7-0.00.1-0.50.91.1-1.31.1-1.1-1.1-0.61.60.7-0.2-1.21.9
Number of licking bursts0.00.10.30.1-0.10.10.00.4-0.2-0.10.00.4-0.20.1-0.1-0.20.6-0.40.2-0.2-0.2-0.10.10.2-0.1-0.30.5
Context. condit. distance diff. score0.10.10.40.30.4-0.40.1-0.20.1-0.0-0.10.00.1-0.1-0.10.1-0.3-0.10.3-0.3-0.3-0.50.10.4-0.6-0.40.4
Locomotion velocity, session 10.40.51.01.00.9-0.91.0-0.90.80.91.00.80.7-0.6-0.5-0.5-0.60.8-0.50.40.40.20.00.10.30.2-0.5
Locomotion distance, session 10.40.52.30.81.5-1.50.8-1.20.60.40.60.70.1-0.10.0-0.3-0.80.8-0.0-0.0-0.1-0.50.31.0-0.6-0.4-0.8
Locomotion velocity, session 20.60.72.91.70.5-0.31.30.10.71.31.41.10.6-0.4-1.3-0.80.2-0.3-0.00.00.00.00.50.40.0-0.51.5
Locomotion distance, session 20.40.51.81.10.7-0.70.5-0.30.00.30.5-0.0-0.10.20.20.30.3-0.40.8-0.8-0.8-0.91.31.3-1.0-1.10.9
Locomotion velocity, session 31.41.64.30.50.4-0.5-0.6-0.3-0.9-0.7-0.7-1.4-0.60.70.61.70.6-1.11.8-1.8-1.8-1.61.82.0-1.5-2.11.1
Locomotion distance, session 30.20.20.70.30.5-0.40.40.1-0.10.30.2-0.4-0.10.20.20.5-0.7-0.30.3-0.3-0.3-0.60.30.6-0.5-0.80.4
Stereotopy head waving bouts, day 30.60.81.8-1.0-0.60.4-1.30.3-1.1-1.3-1.3-1.3-0.60.80.81.30.8-0.60.9-0.9-0.9-0.60.90.5-0.5-0.6-0.2
Stereotopy head waving duration, day 30.80.92.0-1.0-0.50.3-1.20.3-1.2-1.4-1.4-1.4-0.50.70.61.40.8-0.71.0-1.0-1.1-0.71.30.7-0.6-0.9-0.1
Locomotion velocity, session 70.20.20.8-0.3-0.40.4-0.50.3-0.2-0.4-0.2-0.1-0.70.80.90.10.7-0.40.4-0.3-0.3-0.8-0.10.1-0.60.10.5
Locomotion distance, session 70.00.00.10.10.1-0.10.20.00.1-0.00.20.0-0.2-0.1-0.20.1-0.40.1-0.00.0-0.0-0.1-0.10.1-0.30.1-0.1
Stereotopy head waving bouts, day 71.71.94.1-0.3-0.80.8-1.11.0-1.5-1.3-1.2-1.4-0.90.90.61.61.9-1.81.8-1.8-1.7-1.12.01.2-1.2-1.81.7
Stereotopy head waving duration, day 72.93.57.2-1.1-1.71.6-1.81.9-2.2-1.9-1.8-1.9-1.61.61.22.02.7-2.62.1-2.1-2.0-1.32.21.1-1.3-2.02.3
Locomotion velocity, session 80.50.61.50.80.2-0.11.1-0.10.91.11.20.70.9-0.5-0.4-0.8-0.80.5-0.90.91.00.4-0.8-0.80.70.70.2
Locomotion distance, session 80.20.31.21.10.8-0.80.8-0.40.50.50.50.50.5-0.3-0.2-0.3-0.30.00.2-0.2-0.2-0.50.20.6-0.5-0.50.6
Degree of sensitization distance0.40.41.30.00.0-0.00.4-0.40.70.40.50.70.3-0.8-0.7-0.8-0.30.9-0.80.80.80.9-0.5-0.70.51.1-0.9
Degree of sensitization stereotypy2.32.56.00.2-0.60.6-0.91.0-1.4-1.1-1.0-1.2-1.31.10.61.52.2-2.12.2-2.1-2.1-1.52.21.8-1.8-2.32.5
Conditioned locomotion0.20.31.20.50.1-0.00.5-0.30.50.50.50.40.9-1.1-0.7-0.4-0.20.5-0.40.40.41.0-0.3-0.40.60.4-0.3
Cocaine response after cond. corrected0.50.62.4-1.6-1.11.1-0.91.2-1.0-0.9-0.8-0.6-0.80.91.10.50.4-0.60.2-0.1-0.2-0.30.5-0.4-0.20.1-0.0
Cocaine response after cond. not corrected0.91.13.7-1.5-1.41.4-0.91.9-1.3-1.0-0.9-0.5-1.21.41.10.51.2-1.40.6-0.5-0.6-0.80.9-0.2-0.6-0.41.1
Cocaine response before conditioning0.40.52.40.40.2-0.10.10.6-0.4-0.2-0.20.1-0.40.5-0.10.00.5-1.00.8-0.8-0.8-1.00.70.8-0.8-1.31.6
Saline control response1.01.36.62.60.8-0.71.0-1.41.21.00.90.91.9-2.1-2.2-0.70.50.30.2-0.2-0.11.20.20.51.0-0.30.8
Bone: connectivity density0.91.33.30.81.2-1.11.5-1.01.31.31.50.91.2-0.9-0.8-1.1-1.81.4-1.31.31.30.6-1.1-0.50.70.9-1.1
Bone: cortical apparent density2.73.77.8-1.6-0.40.1-2.5-0.1-1.9-2.5-2.5-2.4-2.32.32.82.41.0-1.22.2-2.2-2.1-2.41.12.0-2.2-1.5-0.1
Bone: cortical area1.62.410.82.53.2-3.31.5-2.81.61.11.21.40.7-0.4-0.0-1.0-1.91.30.1-0.1-0.1-1.0-0.72.0-0.8-0.8-0.7
Bone: cortical porosity2.22.36.92.61.2-1.02.4-0.41.72.12.12.51.8-1.6-2.1-2.30.20.5-0.90.90.90.9-0.8-0.21.1-0.01.3
Bone: cortical porosity1.92.07.12.72.0-1.82.2-1.21.71.81.82.11.6-1.5-1.6-1.9-0.50.7-0.60.50.50.5-0.60.50.7-0.50.7
Bone: cortical thickness6.210.223.8-0.41.1-1.5-3.0-1.2-2.4-3.2-3.1-2.7-3.23.64.33.21.5-2.14.2-4.2-4.1-4.72.74.9-4.3-3.81.0
Bone: cortical thickness3.33.99.80.20.7-0.9-1.6-0.5-1.2-1.7-1.7-1.3-2.22.32.51.41.2-1.52.7-2.7-2.6-3.11.33.1-3.0-2.31.4
Bone: cortical tissue density2.73.67.3-1.6-0.50.2-2.5-0.0-2.0-2.5-2.5-2.4-2.22.32.72.41.1-1.22.1-2.1-2.1-2.31.11.9-2.1-1.4-0.1
Condit. Reinf. active minus inactive responses1.71.95.22.01.8-1.72.0-0.91.41.31.22.32.0-2.0-1.9-1.9-1.10.9-0.70.70.61.0-0.40.10.9-0.3-0.0
Condit. Reinf. active-inactive response ratio0.50.52.00.90.6-0.51.10.10.60.60.51.11.3-1.3-1.4-1.1-0.50.2-0.40.40.30.6-0.2-0.30.5-0.20.4
Condit. Reinf. active responses2.53.17.72.32.2-2.12.4-1.41.91.61.62.82.4-2.4-2.1-2.4-1.41.4-1.21.11.01.5-0.9-0.01.3-0.0-0.4
Condit. Reinf. inactive responses1.31.63.41.31.8-1.71.5-1.51.51.11.31.91.2-1.2-0.8-1.5-1.31.5-1.11.11.11.0-1.10.00.90.5-1.2
Incentive salience index mean1.31.64.72.11.5-1.41.8-0.81.41.31.22.21.8-1.8-1.8-1.7-0.60.6-0.60.50.50.9-0.50.20.9-0.40.4
Condit. Reinf. lever presses0.30.41.81.30.3-0.20.4-0.10.40.40.30.90.7-0.7-0.8-0.50.8-0.40.3-0.3-0.30.3-0.00.50.4-0.71.3
Condit. Reinf. active minus inactive responses3.34.211.33.43.1-3.03.3-1.92.32.42.42.52.4-2.5-2.6-2.3-1.81.4-1.00.90.80.9-0.80.80.5-0.60.1
Condit. Reinf. active-inactive response ratio1.11.23.21.61.1-0.91.8-0.41.11.21.21.51.8-1.7-1.8-1.4-0.50.5-0.70.70.61.0-0.5-0.20.9-0.10.4
Condit. Reinf. active responses4.96.915.64.03.7-3.53.9-2.63.13.22.93.33.0-3.2-3.3-3.0-2.42.2-1.61.51.41.5-1.60.51.0-0.0-0.5
Condit. Reinf. inactive responses3.24.110.43.13.2-3.22.7-2.72.52.32.22.51.8-2.0-2.1-2.1-2.22.0-1.00.90.90.7-1.20.90.4-0.1-0.9
Condit. Reinf. lever presses2.02.810.33.22.6-2.52.3-1.81.91.81.82.51.7-1.6-2.1-2.0-0.80.9-0.30.20.20.2-0.61.20.2-0.80.6
Condit. Reinf. lever reinforcers received4.25.912.93.63.3-3.23.5-2.42.92.92.73.12.8-2.9-3.1-2.9-2.22.1-1.51.41.41.4-1.60.31.00.1-0.5
Conditioned reinforcement - actives0.30.41.91.41.0-1.00.5-1.30.50.50.40.21.1-0.9-0.9-0.0-0.10.40.2-0.3-0.30.20.40.8-0.2-0.5-0.1
Conditioned reinforcement - inactives1.01.43.11.61.5-1.51.5-1.61.61.61.81.31.3-1.1-1.1-1.1-1.51.4-0.90.90.90.4-0.50.1-0.00.6-0.7
Conditioned locomotion2.02.65.72.21.8-1.81.8-2.22.01.71.81.42.4-2.2-2.0-1.3-1.51.8-1.11.11.11.3-1.1-0.11.20.7-1.1
Patch foraging indifference point 0 sec3.87.115.33.33.9-3.93.1-3.63.22.62.73.52.8-2.8-2.2-3.0-3.13.1-1.81.71.61.3-1.90.61.30.7-2.2
Patch foraging indifference point AUC1.01.42.81.61.4-1.41.3-1.71.51.51.20.91.3-1.4-1.4-0.9-1.61.3-0.90.80.90.7-0.8-0.10.80.5-0.8
Delay disc. indifference point, 0s delay0.50.62.1-1.5-1.11.0-1.10.8-1.1-1.2-1.1-1.3-0.60.40.61.10.5-0.50.3-0.2-0.30.10.4-0.40.2-0.1-0.4
Delay disc. indifference point, 16s delay0.30.31.6-0.00.8-0.8-0.0-1.0-0.1-0.4-0.4-0.50.9-0.20.10.7-0.50.60.1-0.1-0.20.10.30.50.2-0.4-1.3
Delay disc. indifference point, 2s delay0.80.93.6-0.40.8-0.90.7-0.70.60.30.30.50.6-0.7-0.3-0.7-1.51.3-1.21.21.10.9-1.1-0.70.90.8-1.9
Delay disc. indifference point, 24s delay1.41.55.71.32.1-2.11.0-2.41.30.80.70.81.4-1.1-0.7-0.5-1.81.7-0.60.60.50.4-0.50.60.40.2-1.9
Delay disc. indifference point, 4s delay0.80.81.9-1.2-0.80.7-0.91.0-1.3-1.2-1.1-1.4-1.00.80.91.30.5-1.00.8-0.8-0.8-0.50.90.3-0.6-0.90.4
Delay disc. indifference point, 8s delay0.30.31.2-1.0-0.1-0.0-0.7-0.1-0.7-0.9-0.8-1.1-0.30.20.71.1-0.50.10.2-0.2-0.3-0.00.50.10.0-0.2-1.1
Indifference point function ln k0.50.92.2-0.20.4-0.5-0.60.2-0.8-1.0-0.9-0.3-0.91.11.20.40.9-0.81.2-1.3-1.3-1.40.41.5-1.5-1.50.7
Indifference point function log k0.50.92.2-0.20.4-0.5-0.60.2-0.8-1.0-0.9-0.3-0.91.11.20.40.9-0.81.2-1.3-1.3-1.40.41.5-1.5-1.50.7
Patch foraging total patch changes 0 sec3.77.014.33.33.8-3.73.1-3.53.22.72.73.32.9-2.9-2.2-2.8-3.23.1-1.81.71.71.4-1.90.41.30.8-2.2
Patch foraging total patch changes 12 sec6.07.811.92.82.7-2.53.2-2.83.33.13.03.13.1-3.5-3.2-2.9-3.13.2-2.72.62.62.7-2.1-1.12.61.8-2.2
Patch foraging total patch changes 18 sec2.33.58.93.02.3-2.22.4-2.42.32.42.31.92.2-2.5-2.4-1.6-1.91.8-1.01.01.01.3-0.80.41.00.4-0.7
Patch foraging total patch changes 24 sec3.05.112.03.03.5-3.42.6-3.52.72.32.22.42.3-2.3-2.0-1.9-3.22.7-1.41.31.31.0-1.20.70.90.5-2.0
Patch foraging total patch changes 6 sec3.65.411.12.83.3-3.32.8-3.02.82.52.63.22.1-2.1-1.7-2.8-2.72.7-1.71.61.60.9-1.90.31.10.8-1.8
Patch foraging time to switch 0 sec0.51.03.8-1.2-1.92.0-1.21.5-1.1-0.9-0.7-1.2-0.80.60.51.11.4-1.10.4-0.4-0.30.21.0-0.70.20.20.7
Patch foraging water rate 0 sec1.93.98.82.33.0-3.02.3-2.82.52.22.02.41.8-1.7-1.3-2.2-2.62.4-1.41.31.30.7-1.80.40.40.8-1.7
Patch foraging water rate 12 sec0.71.44.9-0.10.9-1.0-0.6-0.5-0.6-0.8-0.7-0.4-1.51.51.70.70.5-0.51.3-1.3-1.3-2.00.82.0-2.2-1.20.2
Patch foraging water rate 18 sec0.50.82.80.41.5-1.60.2-0.80.0-0.2-0.20.5-0.80.91.2-0.3-0.00.00.7-0.8-0.8-1.60.01.7-1.6-1.0-0.0
Patch foraging water rate 24 sec0.10.20.7-0.10.4-0.40.20.2-0.3-0.0-0.00.1-0.60.50.60.00.2-0.20.3-0.3-0.4-0.60.50.7-0.8-0.60.1
Patch foraging water rate 6 sec0.30.41.40.31.0-1.1-0.1-0.9-0.0-0.2-0.3-0.1-0.50.60.70.10.00.20.5-0.6-0.6-1.00.01.2-1.0-0.6-0.4
Seeking ratio, delayed vs. immediate footshock0.10.10.50.20.4-0.5-0.2-0.70.1-0.1-0.2-0.50.0-0.2-0.10.3-0.50.20.2-0.2-0.20.0-0.10.4-0.1-0.1-0.4
Distance traveled before self-admin1.01.32.3-0.9-0.90.9-0.81.4-1.5-1.1-1.1-1.2-1.21.10.81.30.8-1.51.2-1.2-1.2-1.01.50.7-1.0-1.31.2
Distance traveled after self-admin0.30.41.70.20.1-0.00.20.7-0.5-0.0-0.00.1-0.40.4-0.40.00.3-0.90.7-0.7-0.7-0.80.70.7-0.8-1.11.3
Extensor digitorum longus weight0.83.010.4-3.0-2.82.6-3.20.8-1.6-2.6-2.5-2.0-0.80.91.81.81.4-0.40.4-0.3-0.20.60.0-1.41.01.4-1.4
Bone: elastic displacement2.12.45.0-0.8-0.20.0-1.60.5-1.5-1.7-1.7-1.1-1.72.02.11.31.4-1.51.9-1.9-1.9-2.21.31.7-1.9-1.71.0
Bone: elastic work0.40.51.90.71.3-1.4-0.1-1.30.4-0.00.00.5-0.40.71.1-0.3-0.40.40.4-0.4-0.4-1.1-0.61.2-0.7-0.4-0.2
Bone: endosteal estimation12.427.147.24.73.7-3.16.9-2.56.06.66.66.65.3-5.7-6.3-6.6-4.84.8-5.75.65.55.0-4.9-3.54.53.9-1.9
Bone: endosteal perimeter12.927.647.04.84.2-3.76.9-3.26.06.46.46.05.7-5.9-6.2-6.1-5.55.2-5.75.65.54.9-4.9-3.34.73.7-2.7
Epididymis fat weight0.31.03.01.40.9-0.90.7-1.71.21.01.10.81.2-1.2-1.1-0.6-0.61.3-0.60.60.71.1-0.70.00.90.8-1.1
Delta time in closed arm before/after self-admin0.30.30.9-0.9-0.70.7-0.20.7-0.1-0.1-0.0-0.1-0.70.10.3-0.1-0.20.1-0.60.60.60.5-0.5-0.90.20.8-0.3
Delta time in open arm before/after self-admin0.20.21.0-0.4-0.20.2-0.5-0.1-0.5-0.6-0.7-1.00.4-0.5-0.31.0-0.2-0.10.4-0.4-0.40.40.80.10.1-0.4-0.4
Diff in mean of infusions in LGA sessions1.82.13.2-0.6-1.31.2-1.70.9-1.5-1.4-1.4-1.6-1.41.51.51.81.8-1.71.8-1.8-1.7-1.41.71.0-1.2-1.21.5
Delay discount exponential model param0.20.21.80.4-0.60.6-0.10.60.00.30.30.4-0.40.3-0.2-0.41.0-0.70.3-0.3-0.2-0.30.10.0-0.40.01.3
Extinction: sum of active levers before priming0.10.10.30.30.1-0.1-0.2-0.4-0.1-0.5-0.5-0.20.4-0.3-0.20.3-0.0-0.10.4-0.4-0.4-0.00.30.40.1-0.4-0.0
Active lever presses in extinction session 60.90.82.61.61.0-0.91.1-1.01.11.01.01.11.3-1.2-1.6-0.9-1.00.7-0.40.40.40.6-0.20.10.7-0.00.0
Bone: final force1.01.66.31.42.5-2.51.5-1.71.41.21.21.60.10.10.3-1.4-1.41.2-0.50.40.4-1.0-1.11.0-0.7-0.1-0.7
Bone: final moment1.01.66.51.42.5-2.61.5-1.71.41.21.21.60.00.20.4-1.4-1.41.2-0.50.40.4-1.1-1.21.1-0.8-0.1-0.7
Food consumed during 24 hour testing period1.62.15.42.31.3-1.31.3-2.31.91.61.81.12.1-2.1-1.8-0.9-0.51.7-0.90.91.01.5-0.5-0.01.50.9-1.0
Glucose1.32.03.4-0.9-1.11.0-1.41.1-1.7-1.2-1.4-1.8-1.31.51.31.81.2-1.71.6-1.6-1.6-1.31.91.1-1.3-1.51.3
Heart weight0.60.92.0-0.50.3-0.5-0.9-0.4-1.0-1.2-1.0-1.2-0.70.71.21.30.3-0.41.2-1.2-1.2-1.00.91.4-1.1-1.2-0.3
Delay discount hyperbolic model param0.20.31.80.5-0.50.5-0.10.50.00.30.20.4-0.40.4-0.1-0.31.0-0.70.4-0.4-0.3-0.50.20.2-0.5-0.11.4
Intermittent access intake day 1-15 change0.20.41.7-0.6-1.11.2-0.20.90.10.20.10.2-0.1-0.0-0.2-0.40.5-0.1-0.60.70.70.7-0.7-1.30.61.10.2
Intermittent access intake escalation0.20.41.4-0.1-0.60.60.30.40.50.50.50.60.4-0.5-0.6-0.80.10.3-0.80.90.91.0-1.0-1.20.81.1-0.0
Intermittent access intake escalation 21.01.13.4-0.1-0.80.90.40.40.90.80.80.70.6-0.7-0.9-1.1-0.00.7-1.41.41.51.5-1.7-1.81.21.8-0.3
Intermitt. access day 1 inactive lever presses0.62.35.72.41.3-1.12.0-1.21.92.22.01.82.4-1.8-1.9-1.6-1.01.2-1.11.11.11.0-0.8-0.41.60.60.0
Intermitt. access day 15 inactive lever presses0.61.22.61.20.3-0.21.0-0.91.51.21.51.01.6-1.2-1.1-1.1-0.71.1-1.11.11.21.1-1.1-0.91.01.3-0.4
Intermitt. access escalation Index2.53.56.6-1.5-1.71.6-1.82.1-2.2-2.0-1.7-1.7-1.92.11.61.82.6-2.41.9-1.9-1.9-1.71.81.0-1.6-1.72.0
Intermittent access day 1 total infusions1.01.75.92.32.4-2.41.5-1.91.01.21.21.01.1-0.8-0.8-0.5-1.20.70.3-0.4-0.5-0.70.81.8-0.9-1.2-0.1
Intermittent access day 15 total infusions0.91.33.01.71.6-1.51.4-1.61.31.31.21.21.7-1.4-1.3-1.0-1.11.2-0.60.50.50.6-0.40.30.20.1-0.7
Intermittent access terminal intake (last 3 days)2.33.04.72.01.8-1.72.1-1.82.12.22.21.92.2-1.9-1.9-1.8-1.71.9-1.61.51.51.3-1.3-0.50.81.0-1.2
Intermittent access total infusions2.63.17.62.62.8-2.72.3-2.42.02.02.11.92.1-1.7-1.7-1.6-2.21.8-0.90.80.80.5-0.60.7-0.0-0.0-1.0
Intermittent access day 1 locomotion3.03.812.33.53.3-3.22.4-2.92.22.12.32.02.2-1.9-1.9-1.5-2.01.6-0.40.30.30.1-0.21.60.2-0.7-0.5
Intermittent access day 15 total locomotion3.25.812.33.53.3-3.13.0-3.13.03.02.92.92.9-2.6-2.6-2.5-2.42.5-1.61.51.51.2-1.30.40.90.6-1.2
Intermittent access total locomotion7.59.022.24.74.7-4.63.8-4.23.73.43.63.53.3-3.0-3.0-2.9-3.13.0-1.51.31.40.9-1.41.30.70.1-1.4
Intermittent access standard deviation0.51.01.90.90.8-0.81.2-0.81.31.21.30.91.0-1.0-0.9-1.0-1.41.1-1.11.11.10.8-1.2-0.70.60.9-0.7
Left kidney weight0.41.76.71.01.7-1.80.2-1.0-0.2-0.00.00.2-0.91.10.80.20.1-0.41.4-1.5-1.5-2.31.22.6-2.4-1.80.6
Right kidney weight0.31.35.30.81.6-1.70.0-1.2-0.2-0.1-0.1-0.0-0.70.90.90.40.0-0.21.2-1.3-1.3-2.00.92.3-1.9-1.50.2
Cocaine induced anxiety0.50.72.4-0.40.2-0.2-0.40.7-0.7-0.6-0.70.2-0.81.51.2-0.00.4-0.90.9-0.9-0.9-1.50.40.9-1.4-1.10.9
Post-drug Anxiety0.60.72.0-0.7-0.0-0.1-0.70.5-0.8-0.7-0.9-0.3-1.01.31.40.40.1-0.70.8-0.8-0.8-1.40.50.8-1.3-0.80.4
Baseline Anxiety0.20.21.2-0.4-0.40.4-0.9-0.5-0.3-0.5-0.6-1.1-0.3-0.20.31.00.20.10.3-0.3-0.30.20.40.1-0.40.2-0.6
Tail length2.07.914.53.83.3-3.23.5-3.43.53.43.23.23.0-3.5-3.5-2.9-2.73.0-2.12.02.12.0-1.9-0.21.71.2-1.7
Length with tail1.87.911.42.52.6-2.53.3-2.53.23.43.03.03.0-3.2-3.2-2.9-3.33.2-2.92.92.82.7-2.3-1.32.51.9-2.4
Length without tail0.41.33.1-0.40.1-0.00.6-0.30.71.00.70.50.9-0.9-0.7-0.7-1.51.3-1.61.61.61.8-1.3-1.51.71.4-1.6
Times rat made contact with spout0.40.41.10.90.3-0.20.8-0.40.81.01.10.60.8-0.8-0.8-0.80.20.5-0.60.60.60.7-0.4-0.40.70.50.1
Lifetime Intake3.03.610.03.13.2-3.12.4-2.82.12.12.21.92.2-1.9-1.9-1.5-2.21.8-0.70.60.50.3-0.41.3-0.2-0.4-0.9
Liver weight, left2.43.99.42.82.1-1.93.1-1.42.52.82.72.52.1-2.1-2.7-2.5-1.51.5-1.71.61.61.1-1.5-0.41.00.60.1
Liver weight, right1.22.16.80.50.8-0.9-0.6-0.5-0.8-0.5-0.6-0.5-1.51.51.31.01.1-1.01.9-1.9-1.9-2.42.02.5-2.6-1.70.9
Locomotor activity1.72.69.83.12.8-2.81.4-2.01.01.01.21.30.2-0.4-0.6-0.7-0.0-0.01.2-1.3-1.3-1.51.02.9-1.6-2.11.2
Locomotor testing distance1.42.511.43.42.6-2.51.6-1.81.11.11.21.20.6-1.0-1.2-0.70.2-0.11.2-1.3-1.3-1.00.92.7-1.2-2.21.5
Locomotor testing rearing0.81.68.62.91.0-0.81.5-0.51.21.51.61.70.8-1.1-2.0-1.41.0-0.40.5-0.5-0.4-0.20.21.0-0.4-0.92.3
Locomotion in novel chamber0.10.11.0-0.5-0.30.40.21.0-0.40.00.1-0.0-0.40.60.2-0.00.1-0.5-0.00.0-0.0-0.40.1-0.2-0.3-0.30.6
Locomotion in novel chamber post-restriction1.62.65.00.31.1-1.01.9-0.71.51.71.71.61.4-1.2-1.0-1.9-2.21.9-2.22.22.11.5-1.8-1.51.51.6-1.8
Fecal boli incidents, locomotor time 10.30.41.4-1.0-1.11.1-0.40.9-0.5-0.4-0.4-0.20.5-0.3-0.10.20.2-0.1-0.50.50.40.7-0.3-1.21.10.5-0.3
Change in fecal boli incidents, locomotor task0.40.42.6-0.70.2-0.3-0.3-0.60.3-0.2-0.10.0-0.0-0.10.3-0.2-1.01.0-0.70.70.70.5-0.9-0.50.30.9-1.6
Time >=10cm from walls, locomotor time 11.61.74.4-1.1-1.11.1-0.91.7-1.5-0.8-0.9-0.8-2.11.81.30.81.6-1.71.2-1.1-1.1-1.61.30.6-1.6-1.01.6
Bouts of movement, locomotor time 10.20.20.8-0.7-0.40.3-0.9-0.1-0.3-0.6-0.7-0.1-0.40.60.90.20.30.10.2-0.1-0.1-0.2-0.0-0.1-0.20.4-0.6
Total resting periods, locomotor time 10.20.31.0-1.0-0.60.5-0.90.0-0.3-0.6-0.6-0.1-0.50.50.90.20.00.3-0.10.20.2-0.0-0.3-0.50.00.8-0.9
Rest time, locomotor task time 10.60.72.7-1.7-1.61.6-0.91.2-0.6-0.5-0.5-0.4-0.30.30.30.40.3-0.1-0.60.60.60.7-0.2-1.50.81.1-0.5
Distance moved, locomotor task time 10.30.41.61.31.0-0.90.8-1.20.90.90.90.20.6-0.6-0.5-0.3-0.50.6-0.20.10.20.2-0.30.50.00.1-0.2
Vertical activity count, locomotor time 10.10.20.80.90.8-0.80.7-0.80.60.70.70.30.4-0.3-0.2-0.4-0.20.4-0.10.00.1-0.1-0.30.5-0.2-0.1-0.0
Time >=10cm from walls, locomotor time 20.50.72.9-0.2-1.41.5-0.51.3-0.50.10.1-0.2-1.10.80.30.11.7-1.10.4-0.4-0.3-0.50.6-0.3-0.40.11.6
Bouts of movement, locomotor time 20.20.31.1-0.2-0.60.5-1.0-0.3-0.5-0.7-0.8-1.0-0.20.20.41.00.6-0.40.7-0.7-0.6-0.10.60.4-0.3-0.10.0
Total resting periods, locomotor time 20.30.51.4-0.4-0.60.5-1.1-0.1-0.7-0.9-1.1-1.1-0.40.30.61.20.6-0.60.9-0.9-0.8-0.30.80.5-0.4-0.40.1
Rest time, locomotor task time 23.24.110.9-3.3-2.82.6-2.72.4-2.8-2.6-2.6-2.7-1.61.72.12.61.3-1.81.2-1.2-1.2-0.71.8-0.4-0.6-0.60.2
Distance moved, locomotor task time 20.50.52.51.60.2-0.10.8-0.61.11.41.30.80.3-0.5-0.9-0.90.70.2-0.20.30.40.3-0.5-0.00.10.60.8
Vertical activity count, locomotor time 21.42.06.82.61.3-1.21.7-1.52.02.02.01.81.3-1.4-1.7-1.9-0.11.0-0.80.70.90.8-1.30.10.70.70.4
Light reinforcement 10.41.05.11.31.6-1.7-0.2-2.30.2-0.6-0.3-0.50.7-0.6-0.00.9-0.30.51.0-1.0-1.0-0.30.62.0-0.3-1.2-0.9
Light reinforcement 20.40.63.00.31.2-1.4-0.0-1.70.2-0.3-0.2-0.80.6-0.80.00.8-1.41.00.0-0.1-0.10.20.00.70.3-0.3-1.7
Bone: marrow area11.926.145.34.63.5-3.06.7-2.45.96.56.56.45.1-5.6-6.2-6.5-4.74.7-5.65.55.54.9-4.8-3.54.43.9-1.8
Bone: maximum diameter3.76.914.92.63.3-3.23.6-2.43.03.13.13.12.4-2.4-2.3-3.0-3.92.8-2.52.42.31.5-2.5-0.51.61.1-1.8
Bone: maximum force1.93.412.52.23.5-3.52.3-2.82.01.71.82.10.8-0.7-0.3-1.8-2.52.1-0.90.80.7-0.4-1.21.3-0.4-0.0-1.7
Bone: maximum moment1.93.412.42.13.5-3.52.2-2.72.11.71.82.20.7-0.6-0.3-1.8-2.52.2-1.00.90.8-0.5-1.51.2-0.40.1-1.7
Mean time between licks in bursts0.20.41.6-0.10.2-0.20.2-0.70.50.50.40.00.6-0.4-0.1-0.3-0.31.0-0.80.80.80.7-0.9-0.60.81.0-1.3
Mean num. licks in bursts0.20.30.60.30.3-0.30.3-0.80.60.50.4-0.30.7-0.7-0.40.0-0.60.8-0.50.50.50.6-0.3-0.30.60.6-0.8
Cd content in liver2.52.810.9-3.3-2.92.8-2.02.6-1.5-2.0-1.8-1.2-1.41.51.50.41.8-0.9-0.20.30.30.1-0.7-2.20.21.4-0.0
Co content in liver0.80.91.9-1.4-1.41.3-1.31.2-1.2-1.2-1.3-1.3-0.61.10.91.00.9-1.00.6-0.6-0.5-0.60.5-0.4-0.1-0.20.6
Cu content in liver0.30.41.5-0.1-0.20.30.30.00.40.40.30.50.8-0.6-0.4-0.5-0.20.5-0.80.80.81.1-0.7-0.91.20.8-0.5
Fe content in liver0.40.41.81.10.8-0.70.90.20.20.70.60.8-0.10.0-0.5-0.60.0-0.50.3-0.4-0.4-0.50.20.9-0.4-1.11.4
K content in liver0.20.21.00.30.6-0.60.7-0.20.30.50.60.50.5-0.2-0.3-0.4-1.00.4-0.50.50.50.3-0.3-0.10.6-0.1-0.3
Mg content in liver0.30.31.2-1.1-0.80.8-0.70.7-0.6-0.7-0.6-0.4-0.30.70.40.30.1-0.3-0.10.10.10.0-0.1-0.60.40.2-0.2
Mn content in liver0.30.31.4-0.00.9-1.00.3-0.1-0.2-0.0-0.00.4-0.50.90.6-0.2-0.7-0.10.2-0.3-0.3-1.20.10.9-0.8-0.80.0
Na content in liver0.20.31.30.70.3-0.20.40.2-0.2-0.00.0-0.40.8-0.5-0.90.4-0.3-0.50.4-0.4-0.40.10.30.30.4-1.20.9
Rb content in liver1.82.05.6-1.8-0.90.8-1.41.7-1.7-1.5-1.4-0.9-2.12.41.90.90.8-1.61.2-1.2-1.2-1.80.50.8-1.7-1.21.1
Se content in liver1.21.43.8-0.50.4-0.5-0.80.0-1.3-1.2-1.1-1.3-0.80.91.11.6-0.4-0.91.4-1.5-1.6-1.41.81.7-1.3-2.00.2
Sr content in liver0.40.30.80.80.5-0.50.5-0.90.80.70.70.50.6-0.5-0.3-0.5-0.20.7-0.50.50.50.3-0.5-0.20.50.6-0.4
Zn content in liver0.50.51.2-1.1-0.60.5-0.70.9-1.0-0.8-0.8-0.7-0.80.90.90.70.8-0.70.5-0.5-0.6-0.71.00.2-0.7-0.50.2
Bone: minimum diameter10.318.930.44.54.4-4.15.5-3.85.25.15.15.14.8-4.7-4.5-5.0-4.84.6-4.34.24.13.5-4.2-1.73.42.6-2.6
Time in familiar zone, hab. session 11.61.63.70.10.10.01.0-0.11.11.11.11.31.3-1.2-0.8-1.4-1.11.2-1.71.71.61.7-1.9-1.51.61.6-1.0
Time in novel zone, hab. session 11.71.73.9-0.2-0.20.1-1.20.1-1.1-1.2-1.0-1.3-1.51.41.11.41.4-1.21.7-1.7-1.7-2.01.71.6-1.8-1.41.0
Total zone transitions, hab. session 10.60.83.11.61.7-1.80.8-1.60.90.70.81.00.3-0.2-0.0-0.5-0.20.60.3-0.4-0.3-0.70.21.5-0.8-0.6-0.1
Total locomotion distance, hab. session 11.31.86.62.42.6-2.61.4-2.41.51.21.41.50.6-0.5-0.6-0.9-0.51.20.1-0.1-0.1-0.70.21.7-0.8-0.5-0.5
Locomotion velocity, hab. session 11.21.75.52.32.3-2.31.6-2.21.61.51.51.50.9-0.8-0.9-1.0-0.71.3-0.30.20.2-0.20.11.3-0.3-0.2-0.6
Time in familiar zone, hab. session 21.41.52.71.20.5-0.31.6-0.21.41.51.61.61.4-1.5-1.5-1.6-1.10.8-1.21.21.21.2-1.3-1.11.10.90.2
Time in novel zone, hab. session 21.01.02.7-1.3-0.30.1-1.20.1-1.1-1.1-1.1-1.3-1.51.61.61.20.6-0.40.8-0.8-0.8-1.21.00.8-1.1-0.4-0.7
Total zone transitions, hab. session 20.30.42.11.50.8-0.80.5-1.00.50.50.70.50.4-0.2-0.2-0.10.50.10.5-0.5-0.5-0.40.61.1-0.5-0.50.5
Total locomotion distance, hab. session 20.71.04.01.61.6-1.60.9-2.01.20.91.01.01.0-0.8-0.6-0.6-0.71.2-0.30.20.30.2-0.20.80.10.2-1.0
Locomotion velocity, hab. session 20.60.83.71.41.4-1.50.8-1.91.10.90.90.80.9-0.7-0.5-0.4-0.61.2-0.30.20.30.2-0.10.70.10.2-1.0
Novel to familiar place preference ratio0.70.82.10.81.4-1.40.9-1.11.10.80.71.30.3-0.4-0.2-1.4-0.91.1-0.70.70.70.1-0.90.10.20.4-0.9
Novelty place preference0.40.41.40.71.2-1.20.7-0.90.80.60.51.00.1-0.2-0.1-1.2-0.50.7-0.40.40.4-0.1-0.60.3-0.10.2-0.5
Time in novel zone, NPP test0.40.41.40.71.2-1.20.6-0.70.70.50.51.1-0.1-0.00.0-1.1-0.40.5-0.20.20.2-0.4-0.50.5-0.3-0.0-0.2
Total zone transitions, NPP test0.71.14.71.51.9-1.90.5-1.70.30.20.30.20.0-0.00.20.4-0.30.30.9-1.0-1.0-1.01.02.2-1.3-1.3-0.1
Total locomotion distance, NPP test0.81.13.61.71.9-1.91.3-1.81.31.21.31.20.6-0.7-0.5-0.8-0.91.2-0.40.30.3-0.1-0.11.0-0.40.0-0.7
Locomotion velocity, NPP test0.71.04.51.51.9-1.90.9-2.11.00.80.80.60.7-0.8-0.4-0.2-1.01.2-0.10.00.00.10.21.2-0.2-0.2-1.2
Intraocular pressure0.40.62.01.10.9-1.00.3-1.40.20.20.2-0.41.0-1.2-0.60.6-0.50.50.4-0.4-0.50.61.11.00.3-0.7-0.8
Delta distance traveled before/after self-admin0.40.41.51.10.9-0.90.3-0.70.30.20.20.40.0-0.1-0.3-0.20.3-0.20.7-0.7-0.7-0.70.51.2-0.9-0.90.7
Delta ambulatory time before/after self-admin0.20.30.91.00.9-0.90.5-0.90.70.50.40.70.5-0.5-0.6-0.6-0.10.5-0.10.00.00.0-0.20.5-0.1-0.1-0.1
Parametrial fat weight0.61.35.0-1.6-0.90.90.00.70.30.20.30.50.10.20.4-0.8-0.41.0-1.71.81.70.9-1.4-2.21.22.2-1.5
Pavlov. Cond. lever latency1.01.37.2-2.7-1.61.6-1.11.4-0.9-0.9-0.8-0.7-1.21.01.20.4-0.40.1-0.70.80.70.3-0.5-1.60.31.5-1.3
Pavlov. Cond. magazine entry latency1.82.37.12.72.1-2.02.0-1.61.71.71.52.02.1-1.9-2.1-1.6-1.01.0-0.60.50.50.9-0.40.50.9-0.50.1
Pavlov. Cond. change in total contacts1.41.56.72.61.7-1.61.5-1.41.41.21.11.51.8-1.6-1.8-1.2-0.40.4-0.10.00.10.6-0.10.80.6-0.80.8
Pavlov. Cond. index score1.51.98.12.82.1-2.01.8-1.71.51.51.31.62.0-1.7-1.9-1.2-0.50.6-0.10.00.10.4-0.01.00.5-0.90.6
Pavlov. Cond. latency score1.41.78.12.82.0-1.91.6-1.61.31.41.21.31.8-1.5-1.7-0.9-0.30.40.2-0.2-0.20.20.21.20.2-1.10.8
Pavlov. Cond. lever contacts0.81.05.52.31.1-1.01.1-1.01.01.10.91.01.4-1.3-1.5-0.70.4-0.00.2-0.2-0.20.4-0.00.80.4-0.81.3
Pavlov. Cond. magazine entry number1.11.44.6-2.1-1.71.6-1.61.2-1.2-1.2-1.0-1.5-1.91.61.91.20.7-0.60.3-0.3-0.3-0.70.1-0.5-0.80.7-0.3
Pavlov. Cond. intertrial magazine entries1.72.05.51.52.3-2.31.6-2.01.50.91.01.41.4-1.7-0.9-1.3-2.21.8-0.90.80.71.0-0.90.50.70.0-1.7
Pavlov. Cond. lever-magazine prob. diff.1.51.87.52.72.1-2.01.8-1.71.41.51.31.61.9-1.6-1.8-1.2-0.60.6-0.10.10.10.4-0.01.00.4-1.00.5
Pavlov. Cond. response bias1.62.07.02.62.0-1.91.9-1.51.51.51.41.82.0-1.7-2.0-1.4-0.70.7-0.40.30.30.7-0.20.70.8-0.80.4
Pavlov. Cond. lever latency0.30.51.7-1.3-1.11.0-1.00.5-0.6-0.6-0.6-1.0-0.70.61.00.80.1-0.1-0.10.10.10.1-0.1-0.70.10.7-0.5
Pavlov. Cond. magazine entry latency2.22.64.2-1.6-1.71.6-1.52.0-2.0-1.5-1.5-2.0-1.81.91.31.81.6-2.01.5-1.5-1.5-1.51.70.6-1.3-1.31.5
Pavlov. Cond. change in total contacts0.30.62.91.20.5-0.31.20.20.60.80.80.71.2-0.9-1.7-0.8-0.3-0.1-0.20.20.20.4-0.3-0.10.5-0.51.0
Pavlov. Cond. index score0.20.31.70.60.1-0.00.40.5-0.30.10.00.00.00.2-0.50.00.6-0.80.6-0.6-0.6-0.60.60.6-0.5-1.01.3
Pavlov. Cond. latency score0.40.52.40.4-0.00.10.20.8-0.5-0.1-0.1-0.3-0.30.5-0.30.30.7-1.10.8-0.8-0.9-0.90.90.8-0.8-1.31.5
Pavlov. Cond. lever contacts0.30.41.81.31.1-1.10.8-0.60.50.40.40.80.7-0.6-0.9-0.60.10.00.3-0.3-0.4-0.20.20.9-0.2-0.90.5
Pavlov. Cond. magazine entry number3.34.06.51.71.8-1.71.8-2.32.41.91.92.22.2-2.3-1.7-2.1-2.02.6-2.02.02.02.1-2.1-1.02.01.8-2.1
Pavlov. Cond. intertrial magazine entries9.514.320.83.42.8-2.63.8-3.84.54.14.03.64.4-4.6-3.5-3.7-3.64.5-4.04.04.04.2-3.6-2.34.03.5-3.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.60.30.00.10.20.7-0.4-0.0-0.1-0.1-0.20.4-0.30.10.6-0.90.6-0.6-0.7-0.70.70.6-0.6-1.01.3
Pavlov. Cond. response bias0.20.20.70.80.7-0.70.5-0.20.10.20.20.50.2-0.0-0.5-0.40.3-0.20.4-0.4-0.4-0.50.30.8-0.4-0.80.7
Time in closed arm before self-admin0.70.93.11.31.0-1.00.3-0.70.10.30.30.2-0.40.60.10.00.7-0.51.1-1.1-1.1-1.60.81.8-1.4-1.31.1
Time in closed arm after self-admin0.30.31.5-0.4-0.50.5-0.20.7-0.20.20.30.1-1.21.10.7-0.10.9-0.50.1-0.1-0.0-0.8-0.1-0.0-0.60.20.7
Time in open arm before self-admin1.21.42.6-1.3-1.41.4-1.31.4-1.4-1.2-1.2-1.2-1.61.41.41.11.4-1.30.9-0.9-0.9-0.81.00.2-0.9-0.50.9
Time in open arm after self-admin0.20.20.6-0.4-0.40.4-0.20.2-0.3-0.4-0.5-0.50.6-0.6-0.40.5-0.50.0-0.10.10.00.80.5-0.40.5-0.0-0.5
Bone: periosteal estimation7.415.528.34.44.4-4.15.3-3.44.84.84.95.13.8-3.9-4.0-5.0-4.34.0-3.73.63.52.6-3.7-1.12.52.1-1.8
Bone: periosteal perimeter3.25.611.02.73.1-3.03.3-2.22.82.82.82.82.4-2.2-2.2-2.8-3.22.4-2.12.01.91.1-2.2-0.31.30.7-1.2
Bone: post-yield work1.52.24.71.61.5-1.32.2-0.91.82.02.12.01.2-1.2-1.6-1.9-1.91.4-1.51.41.40.9-1.3-0.50.70.8-0.4
Progressive ratio test 1 active lever presses2.43.09.83.13.0-3.01.9-2.91.91.81.71.91.9-1.7-1.6-1.3-1.61.5-0.20.10.10.0-0.11.6-0.0-0.6-0.6
Progressive ratio test 1 breakpoint2.83.410.53.23.1-3.02.1-3.12.12.01.92.02.1-1.9-1.8-1.5-1.71.7-0.40.30.30.2-0.31.50.2-0.4-0.8
Progressive ratio test 1 inactive lever presses3.14.412.43.53.3-3.22.7-2.92.62.52.82.72.3-1.9-1.8-2.2-1.62.0-0.90.80.80.2-0.71.2-0.1-0.1-0.7
Progressive ratio test 2 active lever presses3.03.57.62.42.5-2.42.4-2.42.02.12.11.72.8-2.4-2.2-1.4-2.42.0-1.31.21.11.3-0.50.21.00.2-1.4
Progressive ratio test 2 breakpoint3.33.88.22.52.5-2.42.5-2.32.12.22.21.72.9-2.5-2.3-1.5-2.52.1-1.41.31.31.4-0.70.01.10.3-1.5
Progressive ratio test 2 inactive lever presses1.93.17.92.42.8-2.81.9-2.82.01.71.81.72.4-1.9-1.5-1.3-2.32.1-0.90.80.80.6-0.50.70.30.1-1.7
Incentive Sensitization - Responses1.31.84.31.31.1-1.01.8-1.11.31.61.70.82.1-1.9-1.8-0.8-1.81.4-1.41.31.31.5-0.4-0.71.20.6-1.1
Incentive Sensitization - Breakpoint1.41.94.31.21.1-0.91.8-1.01.31.71.70.82.1-1.9-1.8-0.8-1.71.4-1.41.41.31.6-0.5-0.81.20.7-1.1
Sum of active levers in priming session hrs 5-61.61.53.1-0.1-0.60.6-1.10.7-1.3-1.4-1.4-0.6-0.40.70.30.91.6-1.61.8-1.7-1.7-1.01.31.2-0.8-1.71.6
Progressive ratio0.30.41.4-1.1-0.40.40.30.7-0.10.10.1-0.00.2-0.0-0.0-0.1-1.20.4-1.01.00.90.6-0.4-1.20.50.7-0.8
Food seeking constrained by brief footshock2.73.36.61.90.20.12.2-0.22.12.62.52.02.1-1.9-2.4-2.3-0.61.2-2.02.02.11.9-1.8-1.92.01.80.4
Seeking ratio, punishment vs. effort1.01.55.82.41.0-0.91.5-1.21.61.61.61.51.5-1.5-1.8-1.50.10.7-0.50.50.60.8-0.80.11.00.30.6
Retroperitoneal fat weight0.41.83.71.61.1-1.01.1-1.91.81.51.51.71.4-1.4-1.2-1.4-0.31.7-1.11.11.21.2-1.1-0.31.11.5-1.2
Reaction time number correct0.61.12.0-1.3-0.1-0.0-1.00.5-1.4-1.3-1.4-0.9-1.31.31.41.10.5-0.71.0-1.0-1.1-1.31.31.0-1.4-1.0-0.3
Reaction time mean minus median0.20.52.0-1.2-1.41.4-0.91.0-0.6-0.6-0.6-0.3-0.50.40.30.11.0-0.4-0.10.20.20.5-0.2-0.90.40.70.0
Reaction time mean minus median AUC0.30.82.0-1.4-0.70.6-1.20.8-1.1-1.3-1.3-0.3-1.41.31.30.41.1-0.70.6-0.6-0.6-0.60.40.3-0.7-0.3-0.0
Reaction time num false alarms2.02.87.52.72.5-2.42.5-1.81.82.32.01.81.9-2.1-2.0-1.4-2.01.2-0.70.70.60.7-0.20.70.6-0.5-0.2
Reaction time num false alarms AUC1.92.96.62.62.4-2.32.5-1.82.02.32.02.02.0-2.1-1.9-1.7-2.11.4-1.01.00.90.9-0.60.40.8-0.1-0.4
Reaction time trials correct on left0.61.12.0-1.3-0.1-0.0-1.00.5-1.4-1.3-1.4-0.9-1.31.31.41.10.5-0.71.0-1.0-1.1-1.31.31.0-1.4-1.0-0.3
Reaction time trials on left0.61.01.9-1.3-0.1-0.0-0.90.5-1.3-1.3-1.3-0.8-1.31.31.41.00.4-0.60.9-0.9-1.0-1.21.20.9-1.4-0.9-0.4
Reaction time mean0.40.72.5-1.4-1.11.1-0.81.6-1.0-0.8-0.8-0.1-1.31.10.90.10.9-0.90.3-0.3-0.3-0.30.2-0.3-0.5-0.10.6
Reaction time mean AUC0.71.13.4-1.5-1.41.4-1.11.8-1.2-1.1-1.1-0.2-1.51.31.00.31.4-1.30.6-0.6-0.6-0.40.3-0.2-0.7-0.31.0
Median of all reaction times0.50.72.2-1.2-0.90.8-0.71.5-1.0-0.8-0.80.0-1.41.21.00.20.8-1.00.5-0.5-0.5-0.60.30.0-0.8-0.50.8
Reaction time omissions0.60.82.6-0.50.0-0.00.4-0.30.70.60.80.70.3-0.2-0.1-0.8-0.91.3-1.31.31.30.8-1.0-1.10.81.6-1.6
Reaction time false alarm rate2.33.17.72.81.8-1.72.5-1.52.22.52.32.02.2-2.4-2.3-1.8-1.71.3-1.21.21.21.3-0.9-0.21.40.30.1
Reaction time premature initiation rate0.81.03.21.51.8-1.81.0-1.81.20.60.70.91.1-0.9-0.8-0.9-1.41.2-0.40.30.30.1-0.80.60.4-0.0-0.8
Reaction time premature initiations0.30.52.30.71.4-1.50.4-1.40.5-0.00.00.40.5-0.3-0.2-0.3-1.00.80.0-0.1-0.1-0.3-0.20.8-0.1-0.4-1.0
Std. dev. reaction times0.40.72.5-1.6-1.61.6-0.61.5-0.5-0.4-0.50.2-0.80.60.4-0.40.7-0.3-0.60.60.60.6-0.6-1.50.51.10.0
Reaction time trials completed0.61.01.9-1.3-0.1-0.0-0.90.5-1.3-1.3-1.3-0.8-1.31.31.41.00.4-0.60.9-0.9-1.0-1.21.20.9-1.4-0.9-0.4
Reaction time trials AUC0.50.91.9-1.3-0.1-0.0-0.90.5-1.2-1.2-1.3-0.7-1.31.31.40.90.4-0.50.8-0.8-1.0-1.21.10.8-1.3-0.8-0.4
Run reversals in cocaine runway, females0.70.72.4-1.2-1.41.3-1.50.3-0.6-0.9-0.8-1.2-0.50.71.11.30.8-0.30.3-0.2-0.1-0.10.2-0.50.10.8-0.3
Run reversals in cocaine runway, males0.20.21.0-1.0-0.40.3-0.30.5-0.4-0.5-0.4-0.4-0.30.20.30.3-0.50.1-0.30.30.20.2-0.0-0.60.30.3-0.6
Latency to leave start box in cocaine runway0.40.41.10.4-0.30.3-0.40.1-0.5-0.2-0.4-0.6-0.20.40.20.70.7-0.80.9-0.9-0.9-0.71.00.8-0.5-0.81.0
Latency to leave start box in cocaine runway, F1.31.53.90.60.0-0.0-0.60.2-1.0-0.6-0.8-1.1-0.50.90.61.30.9-1.51.8-1.8-1.8-1.51.91.7-1.4-2.01.7
Latency to leave start box in cocaine runway, M0.30.20.8-0.0-0.80.8-0.10.30.30.30.30.30.1-0.3-0.4-0.30.40.1-0.40.50.50.6-0.5-0.80.80.90.2
Std. dev. time between licks in bursts0.10.10.60.1-0.30.3-0.3-0.40.10.0-0.2-0.80.4-0.3-0.20.5-0.10.10.0-0.00.00.4-0.0-0.20.40.3-0.2
Total sessions with >9 infusions1.41.77.11.91.9-1.90.1-2.00.1-0.1-0.0-0.20.5-0.4-0.30.7-0.1-0.11.6-1.6-1.6-1.21.62.7-1.3-2.00.2
Short access day 1 total inactive lever presses1.92.57.52.52.7-2.71.9-2.51.81.81.91.61.5-1.4-1.2-1.2-1.91.6-0.50.40.4-0.1-0.21.2-0.7-0.2-0.9
Short access day 10 total inactive lever presses0.20.51.30.20.6-0.70.4-0.70.80.40.50.90.8-0.30.1-0.9-1.11.1-0.80.80.80.3-1.1-0.50.50.8-1.0
Short access day 1 total infusions2.12.711.02.52.7-2.80.6-2.50.30.20.10.30.7-0.6-0.50.4-0.80.01.7-1.8-1.8-1.61.83.3-1.6-2.60.2
Short access day 10 total infusions3.03.810.93.33.2-3.22.2-3.32.32.22.31.81.9-2.0-1.8-1.4-1.92.0-0.60.50.50.3-0.51.4-0.2-0.1-1.0
Short access total infusions1.92.48.22.92.8-2.81.6-2.51.41.31.41.41.3-1.2-1.3-0.8-1.30.90.4-0.5-0.5-0.60.42.1-0.9-1.3-0.1
Short access day 1 locomotion2.73.414.33.03.5-3.61.2-3.81.40.80.90.81.8-1.6-1.3-0.2-1.81.50.7-0.8-0.8-0.50.52.7-0.5-1.5-1.3
Short access day 10 total locomotion3.15.714.73.83.0-2.92.8-3.23.12.72.82.72.9-3.0-2.9-2.4-1.92.4-1.41.31.41.5-1.50.32.00.6-0.9
Short access total locomotion2.93.512.43.43.2-3.21.8-3.52.11.61.81.32.0-2.1-1.9-0.8-1.71.7-0.0-0.1-0.00.3-0.11.90.3-0.7-0.9
One hour access (0.3 mA shock)0.50.61.91.40.8-0.81.1-0.80.91.11.00.71.1-1.1-1.3-0.6-0.70.5-0.40.30.30.50.10.10.1-0.10.1
Compulsive drug intake0.91.02.4-1.1-1.11.1-0.81.6-1.2-0.9-0.8-0.7-1.51.41.00.71.2-1.30.7-0.7-0.7-1.00.80.1-0.8-0.61.2
One hour access (shock baseline)1.11.63.41.71.5-1.41.4-1.71.51.61.41.01.8-1.7-1.4-1.0-1.51.4-0.90.90.91.1-0.6-0.10.40.5-1.0
Social response proportion0.10.20.5-0.4-0.10.1-0.40.4-0.4-0.4-0.6-0.2-0.60.70.50.10.5-0.40.4-0.4-0.4-0.50.10.3-0.4-0.40.2
Social responses0.40.51.91.41.1-1.00.5-0.60.40.50.31.00.00.0-0.4-0.60.7-0.20.6-0.6-0.6-0.70.31.3-0.7-0.90.8
Social time0.40.62.6-1.2-1.51.6-0.51.6-0.8-0.4-0.5-0.8-0.10.4-0.00.60.5-0.8-0.10.10.10.30.3-1.00.40.20.6
Soleus weight0.20.51.90.91.1-1.10.2-0.7-0.1-0.2-0.30.00.5-0.20.00.30.1-0.20.8-0.8-0.8-0.60.81.2-0.4-1.40.3
Bone: stiffness1.01.65.31.72.3-2.31.9-1.51.41.51.61.60.4-0.4-0.4-1.4-1.51.2-0.70.60.5-0.3-0.90.9-0.4-0.2-0.6
Tibialis anterior weight0.20.72.80.70.2-0.2-0.4-1.60.8-0.1-0.10.41.5-1.2-0.4-0.30.41.1-0.40.50.61.2-0.8-0.51.71.0-1.2
Time to tail flick, vehicle, before self-admin0.60.63.2-1.6-1.11.2-0.11.8-0.6-0.3-0.2-0.0-0.70.70.1-0.30.0-0.4-0.70.70.60.2-0.9-1.30.30.50.2
Time to tail flick, vehicle, after self-admin0.10.21.2-0.80.2-0.30.00.0-0.2-0.3-0.4-0.30.20.10.50.1-0.80.4-0.40.40.30.1-0.4-0.40.30.1-1.1
Time to tail flick, test, before self-admin0.30.31.0-0.4-0.70.7-0.10.90.1-0.10.00.9-0.20.2-0.2-1.00.7-0.2-0.40.50.50.3-1.0-0.90.20.60.5
Time to tail flick, test, after self-admin0.10.10.30.10.2-0.20.2-0.10.2-0.1-0.10.60.2-0.3-0.4-0.50.10.2-0.20.20.20.3-0.4-0.10.30.1-0.2
Delta time to tail flick, vehicle, before/after SA1.11.11.90.60.6-0.50.8-1.01.21.01.00.61.3-1.2-0.6-0.8-1.11.4-1.21.21.21.2-1.0-0.91.21.2-1.3
Delta time to tail flick, test, before/after SA0.10.10.3-0.30.3-0.30.30.1-0.1-0.0-0.10.20.00.00.0-0.1-0.50.2-0.30.30.2-0.0-0.1-0.10.1-0.1-0.5
Tibia length0.41.14.20.51.6-1.70.2-0.8-0.4-0.2-0.2-0.3-0.70.60.90.7-0.4-0.21.1-1.1-1.2-1.61.12.1-1.6-1.7-0.0
Ambulatory time before self-admin0.50.81.7-0.5-0.70.7-0.51.1-1.1-0.6-0.6-0.9-0.90.90.51.00.5-1.20.9-0.9-0.9-0.91.30.5-0.8-1.11.1
Ambulatory time after self-admin0.20.20.80.60.5-0.50.3-0.0-0.10.10.10.3-0.10.1-0.4-0.1-0.0-0.40.5-0.6-0.6-0.60.60.9-0.7-0.90.7
Bone: tissue strength1.41.43.4-0.30.3-0.4-0.50.4-1.2-0.8-0.8-0.9-1.51.51.51.20.7-1.11.4-1.4-1.5-1.71.41.7-1.8-1.70.7
Total heroin consumption0.50.52.41.20.5-0.40.80.3-0.10.40.40.30.2-0.2-0.7-0.00.3-0.80.7-0.7-0.8-0.61.10.9-0.4-1.51.6
Bone: trabecular number0.81.34.10.81.5-1.41.5-1.21.21.11.30.71.2-1.0-0.9-0.9-2.01.4-1.21.11.10.6-1.1-0.30.60.5-1.2
Bone: trabecular spacing0.30.41.9-0.2-1.11.2-0.60.9-0.5-0.3-0.4-0.5-0.30.2-0.10.41.4-0.90.4-0.4-0.40.10.6-0.20.1-0.11.0
Bone: trabecular thickness1.01.33.80.51.2-1.20.9-1.51.10.80.80.51.3-1.1-0.7-0.7-2.01.6-1.21.21.21.0-1.1-0.51.10.9-1.8
Bone: trabecular tissue density1.11.53.9-0.80.7-0.9-1.0-0.6-1.0-1.1-1.2-1.3-1.61.21.91.4-0.1-0.31.3-1.3-1.4-1.61.31.8-2.0-1.2-0.8
Water consumed over 24 hours0.20.21.11.00.7-0.70.2-1.00.50.40.70.20.0-0.1-0.0-0.10.50.30.2-0.2-0.2-0.3-0.00.8-0.2-0.10.0
Number of responses in last shaping day0.20.20.70.50.7-0.80.1-0.60.00.0-0.10.30.1-0.3-0.2-0.00.10.10.4-0.5-0.5-0.30.40.8-0.6-0.7-0.1