Hub : Genes

Borcs8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Borcs8 0.03 0.02 3.0e-04 0.03 0.03 0.02 0.03 1.9e-05 8.6e-05 1.8e-04 9.4e-05
2 PL intron excision ratio chr16_19312771_19314845 0.05 0.03 1.1e-05 0.05 0.04 0.04 0.05 2.6e-06 1.9e-05 1.0e-05 4.5e-06
3 BLA mRNA stability Borcs8 0.17 0.09 2.9e-04 0.03 0.05 0.04 0.05 8.1e-03 9.4e-04 5.5e-03 1.7e-03
4 PL mRNA stability Borcs8 0.08 0.04 4.7e-07 0.04 0.05 0.06 0.05 1.4e-05 2.7e-06 1.3e-06 2.5e-06
5 NAcc intron excision ratio chr16_19312771_19314845 0.09 0.04 1.2e-12 0.09 0.08 0.09 0.09 9.9e-14 4.8e-12 1.2e-13 9.6e-14
6 Brain gene expression Borcs8 0.1 0.05 2.4e-06 0.08 0.05 0.04 0.07 1.1e-07 1.2e-05 5.8e-05 8.6e-07
7 pVTA intron excision ratio chr16_19312771_19314845 0.34 0.12 5.4e-15 0.2 0.2 0.2 0.21 1.0e-15 1.5e-15 2.8e-16 1.7e-16
8 IL intron excision ratio chr16_19312771_19314710 0.55 0.21 4.0e-05 0.22 0.14 0.18 0.02 4.6e-06 2.8e-04 3.7e-05 1.0e-01
9 IL intron excision ratio chr16_19312771_19314845 0.51 0.21 8.8e-05 0.21 0.13 0.17 0.02 9.0e-06 4.7e-04 8.1e-05 1.2e-01
10 IC gene expression Borcs8 0.11 0.06 1.7e-04 0.09 0.07 0.06 0.07 1.9e-04 7.6e-04 1.8e-03 5.6e-04
11 Brain intron excision ratio chr16_19312771_19314845 0.36 0.11 0.0e+00 0.32 0.32 0.32 0.32 9.3e-31 5.5e-30 5.6e-31 5.3e-31
12 pVTA intron excision ratio chr16_19312771_19314710 0.4 0.12 0.0e+00 0.24 0.24 0.25 0.26 5.8e-19 2.0e-19 8.0e-20 1.4e-20
13 Brain mRNA stability Borcs8 0.29 0.11 0.0e+00 0.24 0.23 0.24 0.24 1.0e-22 1.9e-21 3.9e-22 3.6e-22
14 Brain intron excision ratio chr16_19312178_19312659 0.22 0.09 2.2e-16 0.19 0.18 0.19 0.19 2.9e-17 8.8e-17 3.5e-17 4.5e-17
15 pVTA gene expression Borcs8 0.05 0.03 3.5e-05 0.04 0.05 0.04 0.05 2.7e-04 4.5e-05 6.7e-04 4.3e-05
16 IL mRNA stability Borcs8 0.24 0.12 1.5e-03 0.06 0.05 0.03 0.07 1.6e-02 2.2e-02 6.0e-02 8.3e-03
17 PL gene expression Borcs8 0.04 0.04 7.7e-04 0.02 0.04 0.03 0.03 2.4e-03 8.3e-05 2.3e-04 6.9e-04
18 NAcc gene expression Borcs8 0.04 0.02 2.7e-06 0.04 0.04 0.03 0.04 4.4e-07 2.7e-06 5.0e-06 8.4e-07
19 Liver gene expression Borcs8 0.05 0.03 9.3e-05 0.04 0.04 0.04 0.04 2.1e-05 2.1e-05 1.6e-05 2.3e-05
20 Eye intron excision ratio chr16_19308424_19309700 0.46 0.19 7.9e-03 -0.02 0.07 0.03 0.05 8.4e-01 2.8e-02 1.2e-01 6.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density3.86.511.62.42.53.43.32.82.72.9-3.03.0-2.62.9-2.82.8-2.90.13.3-0.21.01.11.4
Area under the delay curve0.10.10.7-0.6-0.3-0.0-0.2-0.4-0.5-0.30.3-0.30.2-0.10.4-0.10.00.3-0.80.10.0-0.00.1
BMI with tail1.55.37.92.32.52.22.12.32.42.4-2.62.6-2.32.3-2.42.4-2.4-2.80.5-2.4-2.4-2.4-1.1
BMI without tail3.09.212.43.03.13.02.63.23.23.3-3.33.3-3.23.2-3.23.2-3.2-3.51.1-3.4-3.0-3.0-1.5
Body weight5.122.330.25.35.54.95.15.05.35.3-5.45.4-5.35.2-5.25.2-5.2-4.82.5-3.9-2.9-3.0-0.5
Weight adjusted by age1.62.43.81.31.71.41.41.71.81.7-1.71.7-1.91.5-1.81.6-1.4-1.61.0-1.8-1.2-1.3-0.9
Bone surface2.13.87.81.92.02.82.52.12.02.2-2.32.3-1.92.3-2.22.3-2.3-0.42.1-0.50.30.30.6
Bone volume3.56.211.22.62.73.33.12.82.72.9-2.92.9-2.72.9-2.82.8-2.8-0.72.7-0.80.10.10.6
Breakpoint value in progressive ratio session0.30.41.60.10.3-0.6-0.6-0.7-0.4-0.60.6-0.60.3-0.70.6-0.70.8-0.3-1.3-0.0-0.7-0.6-0.9
Number of licking bursts0.30.41.2-0.6-0.7-0.7-0.6-0.9-0.1-0.50.2-0.20.7-0.50.6-0.50.50.6-1.10.90.60.61.1
Context. condit. distance diff. score0.60.72.6-1.1-1.1-1.0-0.6-0.5-0.6-0.50.5-0.50.7-0.50.5-0.50.50.10.30.91.41.21.6
Locomotion velocity, session 10.60.61.9-0.9-0.9-0.5-1.0-0.8-0.7-0.60.5-0.51.0-0.50.6-0.40.4-0.2-1.4-0.5-1.0-1.0-1.1
Locomotion distance, session 10.50.61.8-1.3-1.3-0.3-0.8-0.9-0.9-0.60.6-0.61.1-0.60.7-0.60.61.2-0.60.80.70.80.2
Locomotion velocity, session 20.70.82.90.30.30.30.00.40.60.7-0.90.9-0.20.6-0.70.8-0.8-1.1-0.9-1.6-1.7-1.7-1.0
Locomotion distance, session 20.91.23.0-1.3-1.3-0.6-1.0-1.2-1.2-1.01.0-1.01.4-1.11.1-1.01.01.7-0.91.20.80.9-0.1
Locomotion velocity, session 32.32.65.0-1.9-2.0-2.2-2.0-1.7-1.9-1.71.7-1.72.1-1.81.7-1.71.70.8-1.40.80.50.30.2
Locomotion distance, session 30.40.41.7-0.4-0.30.40.30.3-0.10.2-0.10.10.10.1-0.20.1-0.10.91.20.81.31.30.9
Stereotopy head waving bouts, day 34.35.08.7-2.0-2.0-2.9-1.8-2.7-2.5-2.42.3-2.32.4-2.22.5-2.22.21.4-1.72.62.11.82.3
Stereotopy head waving duration, day 32.42.95.9-1.6-1.6-2.4-1.5-2.1-1.9-1.81.7-1.71.8-1.61.9-1.61.60.7-1.61.61.21.11.7
Locomotion velocity, session 71.11.32.6-1.4-1.2-1.1-1.3-1.2-1.6-1.21.3-1.31.3-1.31.2-1.21.20.7-0.90.60.20.4-0.5
Locomotion distance, session 70.60.81.2-0.9-0.8-0.7-0.8-1.1-1.0-1.00.9-0.90.7-1.01.0-1.11.11.1-0.91.00.50.7-0.1
Stereotopy head waving bouts, day 70.30.41.5-0.3-0.2-0.7-0.2-0.5-0.7-0.50.5-0.50.4-0.40.5-0.40.40.40.20.91.00.91.2
Stereotopy head waving duration, day 70.30.31.2-0.3-0.3-1.1-0.5-0.6-0.8-0.60.6-0.60.6-0.50.6-0.50.5-0.3-0.30.30.30.20.8
Locomotion velocity, session 84.14.98.8-2.9-3.0-2.8-2.7-2.5-2.4-2.42.3-2.32.5-2.42.4-2.32.30.8-2.21.00.40.50.1
Locomotion distance, session 80.40.51.5-1.2-1.2-0.4-0.7-0.7-0.7-0.50.5-0.50.9-0.60.6-0.50.50.8-0.30.91.01.00.6
Degree of sensitization distance0.80.82.7-0.6-0.7-1.0-1.0-1.1-0.7-1.00.9-0.90.6-1.01.0-1.01.00.2-1.60.2-0.5-0.4-0.7
Degree of sensitization stereotypy0.30.31.20.50.60.40.70.60.40.5-0.50.5-0.50.6-0.50.5-0.5-0.21.10.10.50.50.8
Conditioned locomotion0.10.20.80.80.2-0.20.1-0.2-0.1-0.10.2-0.20.3-0.20.1-0.20.2-0.00.10.80.70.50.9
Cocaine response after cond. corrected0.30.41.50.2-0.1-0.8-0.1-0.3-0.6-0.50.6-0.60.7-0.40.4-0.40.40.10.60.81.01.21.2
Cocaine response after cond. not corrected1.01.22.5-0.5-0.9-1.6-1.1-1.1-1.4-1.31.3-1.31.2-1.31.2-1.21.20.4-0.41.00.70.90.7
Cocaine response before conditioning1.31.64.6-1.5-1.4-1.1-1.7-1.4-1.2-1.21.0-1.00.8-1.31.3-1.31.30.8-2.1-0.1-0.9-1.0-1.5
Saline control response0.10.20.60.0-0.30.70.20.50.10.4-0.40.40.10.4-0.40.5-0.50.10.8-0.30.10.3-0.3
Bone: connectivity density4.26.613.12.22.33.63.13.02.73.0-3.03.0-2.63.0-3.03.0-3.1-0.33.1-0.80.40.40.7
Bone: cortical apparent density0.20.31.90.40.40.90.10.30.10.2-0.20.2-0.30.2-0.20.2-0.20.80.1-0.6-0.7-0.8-1.4
Bone: cortical area6.09.315.93.94.03.23.63.43.43.3-3.23.2-3.63.2-3.33.2-3.1-2.72.7-2.0-1.2-1.1-0.0
Bone: cortical porosity0.10.10.60.10.10.2-0.1-0.2-0.0-0.20.2-0.2-0.2-0.10.2-0.10.1-0.2-0.7-0.2-0.8-0.6-0.8
Bone: cortical porosity0.10.10.30.20.10.30.0-0.20.0-0.10.1-0.1-0.20.10.20.1-0.0-0.2-0.6-0.1-0.5-0.4-0.4
Bone: cortical thickness3.76.211.53.33.42.63.22.72.92.7-2.62.6-3.02.7-2.72.5-2.5-1.72.7-0.9-0.10.00.9
Bone: cortical thickness2.22.69.11.71.90.92.21.11.31.1-1.21.2-1.61.3-1.11.1-1.1-0.42.11.42.22.03.0
Bone: cortical tissue density0.20.21.80.20.20.8-0.00.2-0.00.0-0.10.1-0.10.1-0.10.1-0.10.90.0-0.5-0.6-0.7-1.3
Condit. Reinf. active minus inactive responses0.70.82.90.80.70.71.20.60.80.8-0.80.8-0.80.9-0.70.9-0.90.10.90.71.21.01.7
Condit. Reinf. active-inactive response ratio1.61.73.61.21.21.31.71.21.21.2-1.21.2-1.21.2-1.21.1-1.10.31.80.91.81.41.9
Condit. Reinf. active responses0.50.61.90.70.70.71.10.50.90.8-0.90.9-0.81.0-0.70.9-0.9-0.40.50.30.70.61.4
Condit. Reinf. inactive responses0.50.61.60.30.30.60.30.50.60.7-0.70.7-0.60.8-0.70.9-0.9-1.1-0.2-1.3-1.2-1.0-0.7
Incentive salience index mean0.40.51.21.00.90.81.10.40.80.7-0.80.8-0.70.9-0.60.9-0.9-0.4-0.10.20.30.21.0
Condit. Reinf. lever presses0.30.40.90.90.80.60.70.00.60.4-0.60.6-0.40.7-0.30.8-0.8-0.7-0.9-0.2-0.8-0.60.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.4-0.1-0.3-0.0-0.5-0.20.3-0.30.2-0.20.1-0.30.20.50.30.10.20.0-0.2
Condit. Reinf. active-inactive response ratio0.20.20.80.90.50.20.50.60.30.5-0.50.5-0.50.5-0.50.4-0.5-0.10.3-0.4-0.2-0.20.1
Condit. Reinf. active responses0.71.02.2-1.2-1.5-0.9-1.4-0.9-1.4-1.11.1-1.11.1-1.11.0-1.11.10.9-0.50.30.0-0.2-0.8
Condit. Reinf. inactive responses2.53.26.2-2.2-2.4-1.7-2.5-1.8-2.1-2.02.0-2.02.0-2.11.9-2.02.00.8-1.30.3-0.3-0.5-1.4
Condit. Reinf. lever presses0.50.61.90.1-0.4-0.8-1.0-0.6-0.6-0.60.6-0.60.4-0.60.6-0.60.6-1.0-1.3-0.6-1.2-1.4-1.2
Condit. Reinf. lever reinforcers received0.40.51.1-0.6-0.9-0.7-1.0-0.6-1.0-0.70.8-0.80.7-0.80.7-0.80.80.1-0.5-0.1-0.4-0.6-0.9
Conditioned reinforcement - actives1.72.84.61.81.51.61.72.11.92.0-1.91.9-1.71.9-2.01.9-1.9-1.31.5-1.7-1.0-0.9-0.3
Conditioned reinforcement - inactives6.29.013.43.53.12.63.33.73.43.5-3.43.4-3.23.4-3.53.4-3.4-2.52.8-2.6-1.3-1.30.3
Conditioned locomotion1.31.73.01.51.11.11.31.71.51.6-1.51.5-1.31.5-1.51.5-1.5-1.11.0-1.4-0.8-0.7-0.1
Patch foraging indifference point 0 sec0.71.25.42.01.1-0.10.60.20.70.5-0.70.7-0.80.8-0.40.8-0.9-2.3-1.4-1.2-1.6-1.6-0.2
Patch foraging indifference point AUC0.81.25.6-0.2-0.2-1.0-1.0-1.3-0.8-1.21.2-1.20.3-1.11.2-1.21.1-0.4-2.40.1-1.1-1.3-1.1
Delay disc. indifference point, 0s delay3.53.85.9-2.2-2.2-2.0-2.2-2.4-2.2-2.22.0-2.02.0-2.12.3-2.12.11.7-2.41.50.50.70.2
Delay disc. indifference point, 16s delay0.70.81.8-1.0-1.0-0.7-1.0-1.2-1.1-1.11.0-1.00.8-0.81.1-0.90.70.7-1.30.3-0.0-0.2-0.3
Delay disc. indifference point, 2s delay0.91.01.6-1.1-0.8-0.7-0.7-1.3-1.2-1.11.0-1.01.0-1.01.1-0.91.01.1-1.11.20.70.70.5
Delay disc. indifference point, 24s delay0.20.20.9-0.3-0.3-0.0-0.30.1-0.10.1-0.10.10.00.4-0.10.4-0.4-0.5-0.6-1.0-0.6-0.9-0.2
Delay disc. indifference point, 4s delay0.10.10.4-0.6-0.30.30.1-0.1-0.1-0.10.0-0.00.30.10.10.2-0.20.4-0.5-0.0-0.1-0.1-0.2
Delay disc. indifference point, 8s delay0.10.10.9-0.20.2-0.10.0-0.2-0.2-0.10.0-0.0-0.20.10.20.1-0.1-0.4-1.0-0.3-0.4-0.5-0.1
Indifference point function ln k1.52.74.51.11.31.81.82.01.82.0-2.02.0-1.32.0-2.02.1-2.1-0.92.1-1.00.10.20.7
Indifference point function log k1.52.74.51.11.31.81.82.01.82.0-2.02.0-1.32.0-2.02.1-2.1-0.92.1-1.00.10.20.7
Patch foraging total patch changes 0 sec1.12.28.12.71.60.31.00.71.21.0-1.11.1-1.21.2-0.81.2-1.3-2.8-1.3-1.6-2.0-2.0-0.3
Patch foraging total patch changes 12 sec0.50.74.10.3-0.2-1.1-0.7-0.9-0.4-0.70.5-0.50.3-0.50.7-0.50.4-1.2-2.0-0.4-1.1-1.3-0.4
Patch foraging total patch changes 18 sec1.42.26.3-0.0-0.6-1.9-1.5-1.8-1.5-1.71.7-1.71.3-1.81.8-1.81.8-0.4-2.50.5-0.7-0.8-0.7
Patch foraging total patch changes 24 sec0.20.41.70.60.1-0.9-0.1-0.7-0.3-0.70.6-0.60.1-0.30.7-0.50.4-1.0-1.30.4-0.2-0.30.3
Patch foraging total patch changes 6 sec0.71.06.00.70.0-1.1-0.7-0.8-0.4-0.60.5-0.50.2-0.30.7-0.30.2-1.9-2.5-0.8-1.7-1.7-0.6
Patch foraging time to switch 0 sec0.71.43.6-1.9-1.5-0.8-1.5-1.1-1.3-1.11.0-1.01.2-1.31.1-1.21.31.9-0.70.50.30.3-0.6
Patch foraging water rate 0 sec0.51.13.71.91.40.71.20.71.00.8-0.70.7-1.21.2-0.71.2-1.2-1.6-0.3-0.5-0.8-0.90.3
Patch foraging water rate 12 sec0.92.03.61.91.51.71.71.41.51.6-1.61.6-1.81.6-1.51.6-1.6-1.01.1-0.6-0.2-0.20.3
Patch foraging water rate 18 sec0.40.51.60.60.81.31.00.61.00.7-0.80.8-0.91.0-0.71.0-1.0-0.10.10.1-0.0-0.10.1
Patch foraging water rate 24 sec2.02.85.51.11.62.32.11.81.92.0-2.02.0-1.82.1-1.92.2-2.1-0.51.4-0.50.1-0.20.5
Patch foraging water rate 6 sec1.52.23.41.71.61.41.71.61.71.6-1.61.6-1.51.7-1.61.8-1.7-1.81.1-1.0-0.5-0.70.4
Seeking ratio, delayed vs. immediate footshock0.50.62.4-1.5-1.5-0.5-1.3-0.5-0.8-0.40.3-0.30.9-0.70.5-0.70.70.8-0.9-0.2-0.20.0-0.7
Distance traveled before self-admin0.30.41.50.20.30.1-0.10.30.30.5-0.50.5-0.40.5-0.50.5-0.5-1.1-0.5-1.2-1.1-1.1-0.7
Distance traveled after self-admin0.60.81.70.80.80.50.50.80.90.8-0.90.9-1.10.9-0.80.9-0.9-1.30.3-1.3-1.1-1.1-0.5
Extensor digitorum longus weight0.10.21.10.20.2-0.5-0.3-0.3-0.3-0.1-0.10.10.5-0.20.2-0.10.1-1.0-0.8-0.5-0.7-0.90.1
Bone: elastic displacement0.10.10.8-0.4-0.30.40.10.1-0.00.2-0.20.2-0.20.3-0.20.3-0.30.90.40.20.50.50.1
Bone: elastic work1.62.13.01.61.61.51.61.51.61.6-1.61.6-1.71.7-1.61.7-1.7-1.11.1-1.1-0.6-0.50.0
Bone: endosteal estimation0.30.61.90.70.60.60.40.50.60.7-0.70.7-0.40.7-0.60.8-0.7-1.4-0.4-0.9-1.1-1.1-0.7
Bone: endosteal perimeter0.81.73.71.61.51.01.31.41.11.4-1.31.3-1.21.3-1.41.4-1.4-1.90.8-1.3-1.1-1.0-0.3
Epididymis fat weight2.37.913.72.52.83.72.53.03.03.1-3.23.2-3.03.0-3.13.0-3.1-1.91.4-2.8-2.3-2.4-2.0
Delta time in closed arm before/after self-admin0.10.10.90.20.2-0.2-0.1-0.4-0.3-0.30.2-0.20.5-0.10.30.1-0.0-0.2-0.90.1-0.3-0.5-0.0
Delta time in open arm before/after self-admin0.30.30.6-0.5-0.4-0.2-0.7-0.6-0.5-0.60.6-0.60.2-0.60.5-0.80.70.7-0.10.40.00.0-0.6
Diff in mean of infusions in LGA sessions0.81.04.20.30.2-0.5-0.6-0.10.2-0.1-0.10.1-0.4-0.10.1-0.20.2-1.3-1.6-1.6-2.0-2.1-1.7
Delay discount exponential model param0.00.00.30.30.1-0.1-0.10.10.20.1-0.10.1-0.0-0.2-0.1-0.20.2-0.10.50.0-0.00.0-0.2
Extinction: sum of active levers before priming0.10.10.5-0.10.10.60.0-0.10.3-0.00.1-0.1-0.10.00.00.00.00.6-0.40.2-0.20.1-0.7
Active lever presses in extinction session 60.20.20.5-0.7-0.6-0.4-0.7-0.4-0.4-0.50.5-0.50.6-0.50.4-0.50.50.1-0.2-0.0-0.1-0.1-0.4
Bone: final force4.77.515.73.94.02.43.12.53.02.8-2.92.9-3.22.8-2.72.8-2.7-3.61.0-1.9-1.8-1.90.1
Bone: final moment4.67.315.13.83.92.33.12.53.02.8-2.92.9-3.12.8-2.72.7-2.7-3.61.1-1.9-1.7-1.70.2
Food consumed during 24 hour testing period0.10.10.70.1-0.00.1-0.1-0.4-0.5-0.30.3-0.30.2-0.20.3-0.20.20.7-0.10.80.70.50.3
Glucose0.61.03.91.11.30.30.50.40.70.6-0.70.7-1.00.6-0.50.5-0.6-1.7-0.7-1.3-1.7-2.0-1.1
Heart weight1.21.96.51.01.01.01.61.51.11.3-1.21.2-1.01.4-1.41.5-1.5-0.92.60.01.30.92.1
Delay discount hyperbolic model param0.10.10.50.50.20.0-0.00.30.40.2-0.20.2-0.2-0.0-0.3-0.00.1-0.20.7-0.2-0.1-0.1-0.3
Intermittent access intake day 1-15 change0.71.54.11.11.21.51.61.61.41.4-1.31.3-1.51.3-1.41.2-1.2-0.02.0-0.30.30.40.3
Intermittent access intake escalation0.71.43.90.91.01.51.61.61.31.4-1.21.2-1.51.3-1.31.1-1.20.32.0-0.10.50.70.4
Intermittent access intake escalation 22.02.34.01.31.41.91.62.01.91.8-1.71.7-1.81.7-1.81.6-1.7-0.61.5-1.2-0.5-0.5-0.5
Intermitt. access day 1 inactive lever presses0.10.41.50.20.30.40.41.00.70.8-0.60.6-0.40.6-0.90.6-0.7-0.41.2-0.8-0.3-0.1-0.2
Intermitt. access day 15 inactive lever presses0.00.10.8-0.2-0.3-0.3-0.10.3-0.10.10.1-0.10.3-0.1-0.1-0.00.00.00.9-0.00.50.40.4
Intermitt. access escalation Index0.30.40.8-0.9-0.9-0.4-0.4-0.7-0.6-0.50.5-0.50.6-0.40.6-0.50.40.8-0.60.70.70.70.6
Intermittent access day 1 total infusions0.20.31.80.60.3-0.5-0.10.20.10.1-0.10.1-0.10.1-0.10.2-0.2-1.4-0.7-0.9-0.9-0.9-0.3
Intermittent access day 15 total infusions0.91.42.51.31.11.21.51.61.31.3-1.21.2-1.51.4-1.31.2-1.3-0.41.5-0.6-0.00.10.3
Intermittent access terminal intake (last 3 days)0.71.02.01.41.11.01.21.21.11.1-1.01.0-1.21.1-1.01.0-1.1-0.51.0-0.6-0.3-0.20.1
Intermittent access total infusions1.01.23.01.71.40.81.11.31.11.1-1.01.0-1.21.1-1.11.1-1.1-1.20.6-1.1-0.8-0.7-0.2
Intermittent access day 1 locomotion0.91.23.21.51.30.50.71.00.90.8-0.80.8-1.11.0-0.91.0-1.0-1.8-0.1-1.6-1.5-1.4-0.7
Intermittent access day 15 total locomotion0.40.71.61.31.10.91.00.90.80.9-0.80.8-0.90.9-0.90.9-0.9-0.40.7-0.5-0.3-0.2-0.0
Intermittent access total locomotion1.41.73.61.91.71.01.21.51.31.3-1.31.3-1.41.3-1.31.3-1.3-1.50.5-1.4-1.1-1.1-0.5
Intermittent access standard deviation0.51.01.90.70.61.00.81.41.41.3-1.21.2-0.91.1-1.31.1-1.1-0.51.1-1.0-0.5-0.4-0.1
Left kidney weight0.31.34.61.71.10.40.20.50.50.6-0.70.7-0.60.5-0.60.5-0.5-2.0-1.0-1.5-2.1-1.8-1.5
Right kidney weight1.36.112.62.72.62.31.62.22.12.3-2.32.3-2.12.0-2.32.1-2.1-3.1-0.1-3.3-3.5-3.3-2.8
Cocaine induced anxiety0.40.62.20.10.1-1.0-0.5-0.1-0.4-0.30.3-0.30.3-0.40.3-0.40.4-1.5-1.2-1.1-1.3-1.2-0.9
Post-drug Anxiety0.40.40.9-0.6-0.6-0.9-0.8-0.5-0.7-0.60.6-0.60.7-0.70.6-0.60.6-0.3-0.9-0.3-0.5-0.4-0.6
Baseline Anxiety0.70.83.5-1.0-1.1-0.0-0.6-0.8-0.7-0.70.6-0.60.9-0.60.7-0.60.61.90.11.31.21.20.5
Tail length1.14.25.82.12.02.21.82.32.42.4-2.32.3-2.42.3-2.32.2-2.3-1.71.0-2.1-1.5-1.6-0.7
Length with tail2.18.913.33.63.63.23.23.23.33.4-3.33.3-3.43.3-3.33.2-3.3-2.51.8-2.4-1.7-1.8-0.4
Length without tail1.54.810.33.13.22.33.02.32.32.3-2.22.2-2.62.4-2.32.2-2.3-1.62.3-0.70.0-0.10.9
Times rat made contact with spout0.10.10.90.30.20.20.1-0.3-0.1-0.2-0.00.00.2-0.00.20.1-0.00.9-0.60.60.20.10.3
Lifetime Intake1.51.83.71.91.60.91.41.61.51.4-1.41.4-1.51.4-1.41.4-1.4-1.60.8-1.4-0.9-0.8-0.0
Liver weight, left0.10.11.2-0.10.30.5-0.1-0.1-0.2-0.20.3-0.30.1-0.30.2-0.30.41.10.20.30.00.1-0.8
Liver weight, right2.84.87.12.62.42.71.92.42.42.2-2.12.1-2.32.1-2.22.1-2.1-1.51.1-2.4-2.4-2.1-2.1
Locomotor activity0.61.03.61.11.21.91.20.90.81.0-1.11.1-0.61.2-0.91.3-1.30.70.7-0.1-0.0-0.1-0.1
Locomotor testing distance0.50.82.70.30.41.61.00.80.60.9-0.90.9-0.11.1-0.81.1-1.21.21.30.20.80.70.5
Locomotor testing rearing0.20.41.80.1-0.11.40.40.50.50.5-0.50.5-0.40.9-0.50.9-1.01.00.4-0.3-0.10.0-0.4
Locomotion in novel chamber0.40.51.10.91.00.90.90.70.90.8-0.90.9-1.00.5-0.60.4-0.4-0.2-0.2-0.1-0.3-0.3-0.1
Locomotion in novel chamber post-restriction1.62.76.21.61.72.52.31.51.81.7-1.81.8-1.91.9-1.71.7-1.70.21.80.50.91.11.0
Fecal boli incidents, locomotor time 10.10.20.50.10.20.70.30.10.50.3-0.40.4-0.30.3-0.30.3-0.30.6-0.6-0.3-0.1-0.1-0.7
Change in fecal boli incidents, locomotor task2.12.14.1-0.9-1.4-2.0-1.9-1.8-1.8-1.81.8-1.81.6-1.61.8-1.61.60.1-1.40.7-0.4-0.20.1
Time >=10cm from walls, locomotor time 10.30.41.40.40.2-0.4-0.6-0.5-0.4-0.50.5-0.50.2-0.50.5-0.50.5-0.4-1.2-0.3-0.8-0.8-1.2
Bouts of movement, locomotor time 10.10.11.1-0.30.30.50.0-0.00.1-0.20.2-0.2-0.00.20.10.2-0.20.7-0.3-0.4-0.2-0.5-1.1
Total resting periods, locomotor time 10.10.21.0-0.6-0.10.4-0.2-0.2-0.1-0.30.3-0.30.2-0.10.3-0.00.01.0-0.3-0.10.0-0.3-0.9
Rest time, locomotor task time 10.20.30.8-0.9-0.7-0.8-0.6-0.5-0.5-0.40.3-0.30.8-0.60.4-0.50.50.3-0.70.20.1-0.10.4
Distance moved, locomotor task time 10.10.20.5-0.1-0.4-0.7-0.6-0.5-0.6-0.50.5-0.50.5-0.60.5-0.60.6-0.3-0.50.1-0.1-0.0-0.3
Vertical activity count, locomotor time 10.10.20.50.40.30.70.30.50.40.4-0.40.4-0.20.4-0.40.4-0.4-0.00.5-0.3-0.2-0.2-0.5
Time >=10cm from walls, locomotor time 20.71.12.4-1.0-1.0-0.9-0.8-0.9-0.9-1.01.0-1.00.9-1.11.0-1.21.21.20.11.51.21.30.9
Bouts of movement, locomotor time 20.50.91.9-0.6-0.7-1.4-0.8-1.0-1.0-1.01.0-1.00.8-1.11.1-1.21.20.8-1.20.80.60.40.3
Total resting periods, locomotor time 20.40.81.9-0.5-0.5-1.4-0.8-0.9-1.0-0.91.0-1.00.7-1.01.0-1.11.10.6-1.30.70.50.30.2
Rest time, locomotor task time 20.10.10.40.10.4-0.4-0.0-0.20.1-0.0-0.10.1-0.1-0.00.0-0.00.0-0.4-0.5-0.3-0.6-0.70.2
Distance moved, locomotor task time 20.10.10.5-0.3-0.4-0.0-0.10.2-0.20.00.1-0.10.3-0.2-0.0-0.20.20.10.60.20.70.7-0.1
Vertical activity count, locomotor time 20.30.42.0-0.3-0.10.20.30.40.10.2-0.10.10.00.1-0.20.1-0.10.71.20.71.41.30.8
Light reinforcement 10.10.31.20.3-0.0-0.3-0.5-0.4-0.1-0.20.2-0.20.2-0.40.3-0.50.4-0.3-1.1-0.3-1.0-1.1-0.7
Light reinforcement 20.60.93.20.0-0.3-1.2-1.0-1.1-0.9-0.90.8-0.80.8-1.11.0-1.11.1-0.5-1.8-0.3-1.2-1.1-0.8
Bone: marrow area0.20.51.50.60.60.60.40.40.60.6-0.60.6-0.30.6-0.60.7-0.7-1.2-0.4-0.8-1.0-1.1-0.6
Bone: maximum diameter1.63.05.52.32.31.32.11.81.91.9-1.81.8-2.11.8-1.81.8-1.8-2.21.4-1.1-0.6-0.40.5
Bone: maximum force5.19.117.54.24.23.03.52.93.43.1-3.23.2-3.53.2-3.03.1-3.1-3.41.3-2.0-1.9-1.8-0.0
Bone: maximum moment4.68.115.63.93.92.83.32.83.23.0-3.13.1-3.23.0-2.93.0-3.0-3.21.4-1.9-1.6-1.60.1
Mean time between licks in bursts1.43.44.51.81.91.81.71.92.12.1-2.12.1-2.02.1-2.12.1-2.1-1.81.0-2.0-1.5-1.7-0.5
Mean num. licks in bursts0.40.61.71.11.11.11.11.00.40.7-0.50.5-0.80.8-0.80.8-0.80.21.3-0.20.00.0-0.3
Cd content in liver3.53.97.81.52.42.02.82.02.02.1-2.02.0-2.52.1-2.12.0-2.0-0.72.70.31.30.92.0
Co content in liver0.20.20.9-0.9-0.1-0.6-0.2-0.5-0.3-0.50.4-0.40.1-0.50.5-0.50.50.3-0.30.60.50.40.5
Cu content in liver1.01.23.1-0.7-1.0-0.8-0.6-1.1-1.0-1.00.9-0.91.0-0.91.0-0.90.91.7-0.41.81.61.71.2
Fe content in liver0.60.71.6-0.1-0.7-0.7-0.9-0.8-1.0-1.01.0-1.01.1-1.00.9-1.01.01.3-0.30.70.50.2-0.3
K content in liver2.82.74.7-1.2-2.2-2.0-1.8-1.9-1.7-1.81.6-1.61.7-1.81.8-1.81.81.3-1.71.40.91.20.6
Mg content in liver0.30.30.6-0.4-0.8-0.8-0.5-0.5-0.4-0.50.5-0.50.4-0.60.5-0.60.6-0.0-0.30.60.50.80.5
Mn content in liver0.10.10.6-0.3-0.40.00.10.50.20.4-0.30.3-0.10.2-0.40.2-0.2-0.70.8-0.40.20.40.2
Na content in liver1.01.12.9-1.1-1.7-0.6-1.4-1.2-0.9-1.10.9-0.91.3-1.11.1-1.01.01.4-1.20.60.10.8-0.7
Rb content in liver0.81.03.71.50.70.11.10.90.80.8-0.70.7-0.70.8-0.80.7-0.7-0.91.60.31.11.01.9
Se content in liver0.30.40.9-0.5-0.7-0.6-0.5-0.5-0.5-0.50.6-0.60.4-0.70.5-0.80.80.70.00.80.80.90.3
Sr content in liver0.60.51.80.00.21.30.30.70.70.6-0.50.5-0.90.7-0.70.6-0.70.31.0-1.0-0.8-0.6-1.3
Zn content in liver0.10.10.5-0.2-0.2-0.2-0.3-0.1-0.2-0.30.3-0.3-0.1-0.30.2-0.30.30.2-0.1-0.3-0.4-0.7-0.7
Bone: minimum diameter3.05.58.02.82.82.62.32.52.62.5-2.42.4-2.42.4-2.52.4-2.4-2.31.3-2.2-2.0-2.0-1.3
Time in familiar zone, hab. session 11.01.01.50.70.71.20.71.11.21.1-1.01.0-1.11.0-1.11.0-1.0-0.30.5-1.2-1.0-1.2-0.9
Time in novel zone, hab. session 10.40.43.2-0.2-0.1-0.20.2-0.2-0.2-0.0-0.00.00.30.00.00.0-0.00.30.81.11.51.21.8
Total zone transitions, hab. session 10.10.10.4-0.3-0.30.5-0.1-0.20.20.0-0.10.1-0.20.10.00.1-0.10.3-0.70.0-0.4-0.1-0.6
Total locomotion distance, hab. session 10.10.21.3-0.4-0.50.90.10.00.40.2-0.30.3-0.20.3-0.20.3-0.31.1-0.20.40.10.3-0.3
Locomotion velocity, hab. session 10.10.20.9-0.6-0.70.6-0.3-0.20.1-0.1-0.00.00.1-0.00.1-0.00.00.9-0.70.2-0.3-0.1-0.8
Time in familiar zone, hab. session 20.50.51.20.20.10.80.41.00.50.8-0.70.7-0.30.7-0.90.9-0.9-0.70.9-1.1-0.6-0.7-0.5
Time in novel zone, hab. session 20.20.20.70.30.4-0.10.2-0.10.1-0.10.1-0.1-0.3-0.20.2-0.30.30.60.30.80.70.50.7
Total zone transitions, hab. session 20.10.10.2-0.2-0.2-0.3-0.2-0.3-0.3-0.30.3-0.30.4-0.40.3-0.40.40.10.00.40.30.40.1
Total locomotion distance, hab. session 20.30.31.3-0.00.00.60.50.40.30.4-0.30.3-0.10.2-0.40.2-0.20.71.10.81.21.10.8
Locomotion velocity, hab. session 20.20.20.8-0.2-0.20.50.30.20.10.3-0.20.20.10.1-0.20.1-0.10.80.70.70.90.90.5
Novel to familiar place preference ratio0.50.51.21.01.10.90.80.70.80.7-0.70.7-0.80.7-0.70.7-0.7-0.30.3-0.4-0.6-0.4-0.5
Novelty place preference0.20.20.60.70.80.60.60.50.60.4-0.40.4-0.60.5-0.40.4-0.4-0.10.2-0.3-0.5-0.2-0.3
Time in novel zone, NPP test0.10.10.50.60.70.60.40.30.40.3-0.30.3-0.40.3-0.30.3-0.30.10.2-0.1-0.4-0.2-0.3
Total zone transitions, NPP test0.40.51.5-0.7-0.6-0.4-0.5-1.0-0.4-0.80.7-0.70.6-0.60.8-0.60.60.8-0.81.20.80.80.5
Total locomotion distance, NPP test0.50.62.2-0.9-0.90.1-0.2-0.7-0.4-0.40.3-0.30.7-0.30.5-0.30.31.5-0.21.51.41.30.9
Locomotion velocity, NPP test0.40.61.9-1.1-1.1-0.0-0.4-0.8-0.5-0.50.4-0.40.8-0.40.6-0.40.41.4-0.71.21.11.10.5
Intraocular pressure0.60.82.21.10.90.51.11.11.01.1-1.01.0-0.61.0-1.11.0-1.0-0.41.5-0.50.20.20.9
Delta distance traveled before/after self-admin0.70.71.31.11.10.90.80.91.10.8-0.80.8-1.10.8-0.80.7-0.7-0.50.6-0.9-0.9-0.9-0.6
Delta ambulatory time before/after self-admin0.10.10.40.60.60.20.40.30.50.1-0.20.2-0.40.1-0.10.0-0.0-0.00.4-0.2-0.3-0.2-0.2
Parametrial fat weight2.76.412.12.62.42.11.82.42.62.5-2.52.5-2.52.4-2.52.4-2.4-3.50.6-3.4-3.1-3.1-1.8
Pavlov. Cond. lever latency0.10.21.7-0.3-0.1-0.0-0.10.6-0.20.3-0.10.10.30.0-0.40.1-0.1-0.41.3-0.50.20.1-0.1
Pavlov. Cond. magazine entry latency0.20.30.60.70.60.60.50.30.60.5-0.50.5-0.80.6-0.40.5-0.5-0.2-0.3-0.3-0.7-0.7-0.2
Pavlov. Cond. change in total contacts0.20.31.70.80.7-0.10.4-0.40.40.0-0.20.2-0.60.20.20.1-0.1-0.3-1.30.3-0.4-0.60.7
Pavlov. Cond. index score0.10.11.60.20.10.2-0.0-0.50.1-0.20.0-0.0-0.30.00.3-0.00.00.3-1.30.1-0.6-0.6-0.3
Pavlov. Cond. latency score0.30.32.9-0.1-0.3-0.3-0.4-1.0-0.2-0.60.4-0.40.1-0.40.7-0.40.40.5-1.70.5-0.4-0.4-0.1
Pavlov. Cond. lever contacts0.20.21.80.40.20.10.1-0.50.2-0.1-0.00.0-0.30.00.20.0-0.00.1-1.3-0.0-0.7-0.7-0.4
Pavlov. Cond. magazine entry number0.30.41.0-0.7-0.6-0.6-0.5-0.4-0.6-0.50.6-0.60.8-0.60.5-0.60.60.50.30.60.91.00.4
Pavlov. Cond. intertrial magazine entries1.31.57.0-0.20.00.61.10.70.40.7-0.60.6-0.20.7-0.70.7-0.70.91.91.22.42.72.5
Pavlov. Cond. lever-magazine prob. diff.0.10.11.40.10.00.0-0.1-0.50.0-0.20.1-0.1-0.2-0.10.3-0.10.10.2-1.20.1-0.6-0.6-0.3
Pavlov. Cond. response bias0.20.30.60.70.60.60.60.10.50.4-0.50.5-0.80.6-0.30.5-0.5-0.1-0.6-0.1-0.6-0.6-0.1
Pavlov. Cond. lever latency0.60.83.0-0.9-0.10.80.70.50.40.5-0.50.5-0.20.5-0.50.5-0.51.41.50.91.71.71.3
Pavlov. Cond. magazine entry latency0.40.51.51.10.3-0.6-0.4-0.4-0.1-0.40.3-0.3-0.2-0.50.4-0.50.6-0.8-1.1-0.4-1.2-1.1-0.9
Pavlov. Cond. change in total contacts0.60.93.00.6-0.2-1.4-0.9-1.0-0.9-0.90.8-0.80.3-0.90.9-0.90.9-1.3-1.7-0.3-1.2-1.3-0.7
Pavlov. Cond. index score0.70.93.01.10.1-1.1-0.7-0.7-0.4-0.60.5-0.50.0-0.70.6-0.70.7-1.5-1.7-0.7-1.6-1.6-1.0
Pavlov. Cond. latency score0.70.93.00.8-0.2-1.2-0.9-0.9-0.6-0.80.8-0.80.2-0.90.9-0.90.9-1.0-1.7-0.4-1.3-1.3-0.9
Pavlov. Cond. lever contacts0.60.92.70.7-0.1-1.1-0.9-0.8-0.7-0.70.7-0.70.5-0.80.7-0.80.7-1.2-1.7-0.7-1.4-1.5-1.1
Pavlov. Cond. magazine entry number0.70.93.9-1.4-0.80.30.20.2-0.20.1-0.00.00.60.1-0.10.2-0.21.71.31.12.01.91.3
Pavlov. Cond. intertrial magazine entries0.20.21.1-1.0-0.30.80.20.40.10.4-0.30.30.20.3-0.40.4-0.40.70.80.10.50.60.1
Pavlov. Cond. lever-magazine prob. diff.0.70.93.01.20.2-0.9-0.6-0.7-0.3-0.50.4-0.4-0.1-0.60.5-0.60.6-1.5-1.7-0.8-1.7-1.7-1.1
Pavlov. Cond. response bias0.70.93.61.00.3-0.7-0.6-0.4-0.3-0.30.3-0.3-0.0-0.40.3-0.40.4-1.7-1.5-1.1-1.9-1.9-1.4
Time in closed arm before self-admin1.51.97.30.60.5-0.10.31.41.31.3-1.21.2-1.31.1-1.31.2-1.2-2.70.1-2.7-1.9-1.8-0.7
Time in closed arm after self-admin1.31.34.31.00.80.10.71.31.21.2-1.21.2-1.11.1-1.21.2-1.2-2.10.4-1.8-1.2-1.30.0
Time in open arm before self-admin0.20.21.40.2-0.10.60.2-0.2-0.2-0.20.1-0.10.4-0.10.2-0.00.01.2-0.10.80.50.70.0
Time in open arm after self-admin0.40.52.9-0.3-0.40.70.1-0.3-0.2-0.30.3-0.30.1-0.30.3-0.40.41.70.71.31.21.30.3
Bone: periosteal estimation2.24.77.22.72.72.32.42.32.42.4-2.32.3-2.32.3-2.42.3-2.3-2.41.4-1.7-1.3-1.2-0.4
Bone: periosteal perimeter3.56.09.33.13.02.12.82.82.52.7-2.62.6-2.72.6-2.72.6-2.6-2.82.3-2.0-1.2-1.00.1
Bone: post-yield work0.10.10.40.60.60.40.60.10.20.1-0.20.2-0.10.2-0.10.2-0.20.00.10.60.40.50.5
Progressive ratio test 1 active lever presses0.60.83.81.31.1-0.10.50.50.70.5-0.60.6-0.80.6-0.50.6-0.6-1.9-0.7-1.2-1.3-1.3-0.3
Progressive ratio test 1 breakpoint0.60.73.41.21.0-0.10.50.50.70.5-0.50.5-0.80.6-0.40.6-0.6-1.8-0.7-1.1-1.2-1.2-0.2
Progressive ratio test 1 inactive lever presses1.11.63.11.20.90.90.91.71.41.5-1.41.4-1.11.4-1.51.4-1.4-1.11.2-1.8-1.0-0.9-0.5
Progressive ratio test 2 active lever presses0.50.61.31.10.90.50.70.80.70.8-0.80.8-0.90.8-0.80.8-0.9-1.00.2-1.0-0.9-0.6-0.2
Progressive ratio test 2 breakpoint0.40.51.01.00.80.40.60.70.60.7-0.70.7-0.80.8-0.70.7-0.8-0.80.2-0.8-0.8-0.5-0.2
Progressive ratio test 2 inactive lever presses0.50.81.71.31.00.31.01.01.01.0-0.90.9-0.90.9-0.90.9-0.9-1.10.6-0.6-0.3-0.20.7
Incentive Sensitization - Responses0.10.10.20.40.30.20.30.20.20.3-0.30.3-0.40.3-0.30.2-0.3-0.1-0.0-0.2-0.3-0.10.0
Incentive Sensitization - Breakpoint0.00.00.10.30.20.20.20.10.10.2-0.20.2-0.30.2-0.20.1-0.20.1-0.0-0.1-0.3-0.1-0.1
Sum of active levers in priming session hrs 5-61.41.35.5-1.0-0.40.20.2-0.6-0.4-0.60.6-0.60.4-0.60.6-0.80.82.30.92.32.02.11.3
Progressive ratio0.10.10.50.10.0-0.10.1-0.1-0.2-0.10.2-0.20.1-0.20.1-0.20.3-0.20.70.60.50.50.5
Food seeking constrained by brief footshock1.21.45.00.30.40.81.30.50.50.5-0.50.5-0.40.6-0.50.5-0.51.02.21.62.22.22.2
Seeking ratio, punishment vs. effort0.40.61.7-0.10.10.90.80.50.60.6-0.60.6-0.40.7-0.60.7-0.71.30.90.61.11.01.0
Retroperitoneal fat weight2.912.416.73.63.73.73.43.83.94.0-4.14.1-3.73.8-3.93.9-3.8-4.02.1-3.4-2.4-2.5-0.7
Reaction time number correct0.61.23.20.40.41.80.81.21.51.3-1.31.3-1.21.1-1.31.1-1.10.00.8-0.9-0.6-0.6-1.0
Reaction time mean minus median0.30.82.7-0.3-0.5-1.1-0.9-1.1-1.0-1.00.9-0.90.7-0.91.0-1.00.90.1-1.60.2-0.7-0.8-0.7
Reaction time mean minus median AUC0.20.61.9-0.3-0.6-1.2-0.8-0.9-0.9-0.90.8-0.80.6-0.70.8-0.80.7-0.3-1.40.0-0.7-0.6-0.4
Reaction time num false alarms0.10.20.80.60.3-0.8-0.0-0.2-0.3-0.10.1-0.10.1-0.40.2-0.50.4-0.9-0.5-0.0-0.3-0.30.2
Reaction time num false alarms AUC0.20.31.40.50.1-1.2-0.2-0.5-0.6-0.50.5-0.50.3-0.70.5-0.80.7-0.5-0.70.4-0.0-0.00.3
Reaction time trials correct on left0.61.23.20.40.41.80.81.21.51.3-1.31.3-1.21.1-1.31.1-1.10.00.8-0.9-0.6-0.6-1.0
Reaction time trials on left0.71.33.40.50.51.80.81.31.61.3-1.41.4-1.31.2-1.31.2-1.1-0.00.7-1.0-0.7-0.7-1.2
Reaction time mean0.30.41.90.40.6-0.3-0.00.20.00.1-0.00.0-0.20.1-0.20.0-0.1-1.3-0.4-1.0-1.3-1.4-1.0
Reaction time mean AUC0.40.62.0-0.2-0.1-1.0-0.8-0.5-0.6-0.60.6-0.60.4-0.60.5-0.60.5-0.8-1.1-0.8-1.3-1.4-1.2
Median of all reaction times0.20.31.70.40.6-0.20.10.40.20.3-0.20.2-0.30.2-0.40.2-0.3-1.30.1-1.0-1.0-1.1-0.7
Reaction time omissions0.71.04.80.90.9-0.2-0.00.00.20.0-0.10.1-0.60.2-0.00.2-0.2-1.5-1.4-1.4-2.1-2.2-1.5
Reaction time false alarm rate0.40.51.90.50.3-1.4-0.1-0.7-0.8-0.70.7-0.70.5-0.70.7-0.80.7-0.6-0.70.70.30.31.0
Reaction time premature initiation rate0.50.71.4-0.6-0.3-0.7-0.3-1.1-0.9-1.01.0-1.00.8-0.71.1-0.80.70.3-0.91.20.60.50.7
Reaction time premature initiations0.00.00.3-0.3-0.00.30.1-0.30.1-0.20.2-0.20.00.00.2-0.0-0.0-0.0-0.60.3-0.1-0.1-0.2
Std. dev. reaction times0.20.42.00.50.6-0.3-0.2-0.2-0.3-0.10.2-0.2-0.1-0.10.1-0.20.0-0.8-1.0-0.7-1.4-1.4-1.1
Reaction time trials completed0.71.33.40.50.51.80.81.31.61.3-1.41.4-1.31.2-1.31.2-1.1-0.00.7-1.0-0.7-0.7-1.2
Reaction time trials AUC0.91.74.00.70.62.01.01.51.71.5-1.61.6-1.51.4-1.51.4-1.3-0.20.8-1.2-0.8-0.8-1.2
Run reversals in cocaine runway, females2.42.44.81.91.81.11.61.71.61.7-1.61.6-1.81.7-1.71.7-1.7-2.20.9-1.6-0.9-1.00.0
Run reversals in cocaine runway, males1.51.52.5-1.0-1.0-1.3-1.2-1.3-1.4-1.41.4-1.41.6-1.51.4-1.41.41.1-1.01.00.40.5-0.2
Latency to leave start box in cocaine runway0.30.40.60.20.30.70.40.70.60.7-0.80.8-0.10.7-0.70.7-0.8-0.5-0.0-0.7-0.7-0.7-0.5
Latency to leave start box in cocaine runway, F0.70.81.30.70.91.00.91.00.91.1-1.11.1-0.51.1-1.01.1-1.1-0.70.4-0.7-0.5-0.6-0.0
Latency to leave start box in cocaine runway, M0.30.30.8-0.9-0.8-0.5-0.7-0.5-0.4-0.50.4-0.40.5-0.50.5-0.50.50.2-0.8-0.1-0.3-0.1-0.6
Std. dev. time between licks in bursts1.92.63.91.32.01.71.81.71.71.9-1.81.8-2.01.9-1.81.9-1.9-1.41.1-1.2-0.7-1.20.2
Total sessions with >9 infusions2.32.85.52.12.01.01.61.91.81.8-1.71.7-2.01.7-1.81.7-1.7-2.31.0-1.8-1.3-1.2-0.0
Short access day 1 total inactive lever presses2.12.84.71.41.21.41.72.22.02.1-2.02.0-1.52.0-2.12.0-2.0-0.92.0-1.4-0.2-0.20.7
Short access day 10 total inactive lever presses1.12.76.0-2.1-1.9-2.4-2.1-1.6-1.7-1.81.8-1.82.0-1.91.8-1.81.80.2-1.50.2-0.1-0.2-0.4
Short access day 1 total infusions4.25.67.82.42.42.42.62.82.82.8-2.82.8-2.82.8-2.82.8-2.7-1.72.0-2.0-0.9-0.90.3
Short access day 10 total infusions1.31.72.51.31.01.11.51.61.61.5-1.51.5-1.41.6-1.51.5-1.6-1.11.2-0.9-0.1-0.20.8
Short access total infusions1.52.03.11.81.40.91.41.61.61.5-1.51.5-1.61.5-1.51.5-1.5-1.70.7-1.4-0.9-0.90.2
Short access day 1 locomotion5.06.28.72.42.32.12.53.02.82.9-2.82.8-2.82.9-2.92.9-2.9-2.72.2-2.4-1.1-1.20.3
Short access day 10 total locomotion2.34.36.72.12.12.32.32.62.42.5-2.42.4-2.42.4-2.52.3-2.3-1.22.3-1.4-0.3-0.40.3
Short access total locomotion2.83.35.02.22.11.62.12.22.02.1-2.02.0-2.12.0-2.12.0-1.9-1.91.7-1.3-0.5-0.50.5
One hour access (0.3 mA shock)0.70.82.11.00.60.61.30.80.90.9-0.90.9-1.11.0-0.80.9-0.90.11.00.20.80.71.5
Compulsive drug intake1.11.32.0-1.2-1.1-1.2-0.9-1.4-1.3-1.31.3-1.31.0-1.21.3-1.21.21.0-0.61.41.11.10.8
One hour access (shock baseline)1.62.43.71.91.51.31.71.91.81.8-1.71.7-1.81.8-1.81.7-1.7-1.31.2-1.4-0.6-0.60.1
Social response proportion2.83.16.12.22.31.72.51.81.71.9-1.71.7-1.91.7-1.81.7-1.6-0.52.40.41.21.12.1
Social responses1.51.93.50.91.21.71.91.31.31.4-1.41.4-1.31.5-1.31.4-1.40.91.80.61.31.31.6
Social time0.40.62.5-0.2-0.2-0.7-0.0-0.6-0.5-0.60.6-0.60.5-0.40.6-0.40.50.80.51.21.41.31.6
Soleus weight0.51.64.91.41.30.50.70.71.30.9-1.11.1-1.11.0-0.81.0-1.0-2.2-1.0-1.5-2.0-2.0-0.6
Bone: stiffness2.74.49.43.13.01.72.32.02.22.1-2.12.1-2.32.1-2.02.1-2.1-2.90.8-1.6-1.5-1.60.0
Tibialis anterior weight0.20.71.51.01.11.20.80.80.70.9-1.01.0-0.60.8-0.80.8-0.8-0.30.2-0.6-0.7-0.7-0.4
Time to tail flick, vehicle, before self-admin0.20.21.41.20.80.20.70.50.30.1-0.10.1-0.30.3-0.20.4-0.3-0.50.70.10.1-0.10.3
Time to tail flick, vehicle, after self-admin0.20.31.5-0.6-0.00.3-0.30.50.30.3-0.20.20.10.2-0.40.2-0.2-0.80.2-1.1-0.8-0.9-1.2
Time to tail flick, test, before self-admin0.40.41.20.60.8-0.20.70.60.60.7-0.70.7-0.80.4-0.60.3-0.3-1.10.4-0.3-0.00.10.8
Time to tail flick, test, after self-admin0.70.82.0-0.5-0.3-1.1-0.5-1.0-0.8-1.01.0-1.00.3-1.01.0-1.11.20.7-0.41.40.90.80.7
Delta time to tail flick, vehicle, before/after SA0.30.32.6-1.6-0.9-0.1-0.8-0.1-0.20.00.0-0.00.6-0.2-0.0-0.10.10.1-0.1-0.5-0.1-0.1-0.6
Delta time to tail flick, test, before/after SA0.10.10.7-0.0-0.10.50.0-0.2-0.1-0.30.3-0.3-0.20.00.20.00.00.80.10.60.40.3-0.2
Tibia length0.30.81.51.21.10.61.10.81.11.0-1.01.0-0.81.0-0.91.0-1.0-1.20.2-0.4-0.5-0.20.6
Ambulatory time before self-admin0.60.93.30.20.30.2-0.20.60.50.7-0.70.7-0.70.7-0.70.8-0.8-1.5-0.8-1.8-1.6-1.6-1.2
Ambulatory time after self-admin1.21.53.21.11.30.90.71.11.11.0-1.11.1-1.51.2-1.11.1-1.2-1.40.1-1.8-1.6-1.6-1.0
Bone: tissue strength0.50.52.70.30.30.0-0.40.0-0.0-0.10.1-0.1-0.0-0.10.0-0.10.1-1.0-0.7-1.0-1.5-1.6-1.6
Total heroin consumption0.40.52.30.00.3-0.6-0.6-0.6-0.3-0.60.5-0.50.6-0.60.6-0.50.5-0.6-1.5-0.3-1.0-1.0-1.0
Bone: trabecular number4.47.314.02.52.63.73.33.03.03.2-3.23.2-2.93.2-3.13.2-3.2-0.52.9-1.00.20.20.7
Bone: trabecular spacing0.81.12.2-0.9-0.9-1.5-1.3-1.1-0.8-1.11.2-1.20.8-1.31.1-1.31.3-0.0-1.40.1-0.5-0.4-0.6
Bone: trabecular thickness2.12.65.11.92.02.32.21.61.51.7-1.81.8-1.71.8-1.61.8-1.80.01.70.00.50.50.9
Bone: trabecular tissue density0.30.51.9-0.3-0.3-0.1-0.7-0.8-0.8-0.70.6-0.60.2-0.70.7-0.70.70.4-1.30.0-1.0-0.5-1.4
Water consumed over 24 hours0.20.21.01.01.00.70.7-0.10.40.2-0.30.3-0.80.4-0.10.4-0.30.2-0.30.50.1-0.00.3
Number of responses in last shaping day1.01.12.11.11.11.01.50.91.31.0-1.11.1-1.31.1-1.01.1-1.0-0.20.80.30.70.61.3