Hub : Genes

Bltp3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_039099274.2 0.08 0.05 7.4e-05 0 0.01 0.01 0.01 1.7e-01 1.3e-02 1.6e-02 2.5e-02
2 Liver alternative TSS XM_039099274.2 0.08 0.05 9.1e-05 0.01 0.02 0.01 0.02 9.2e-03 4.6e-03 1.2e-02 3.0e-03
3 Adipose alternative TSS XM_039099274.2 0.25 0.09 6.5e-06 0 0.02 0.02 0.02 1.8e-01 1.2e-03 1.4e-03 2.7e-03
4 Brain isoform ratio XR_005497711.2 0.03 0.02 3.5e-03 0.02 0.03 0.01 0.02 2.5e-03 1.9e-03 5.6e-02 5.4e-03
5 Adipose gene expression Bltp3a 0.59 0.09 0.0e+00 0.45 0.34 0.49 0.38 2.9e-55 1.6e-38 1.2e-62 1.4e-44
6 NAcc alternative TSS XM_002728921.6 0.03 0.02 9.3e-03 0 0.01 0.01 0 2.4e-01 7.3e-03 2.7e-02 8.1e-02
7 Adipose alternative TSS XM_039099274.2 0.25 0.09 1.7e-05 0.01 0.02 0.02 0.02 2.9e-02 2.4e-03 1.0e-03 1.2e-03
8 Brain mRNA stability Bltp3a 0.06 0.03 2.3e-06 0.06 0.03 0.03 0.06 4.5e-06 4.3e-04 6.5e-04 5.6e-06
9 Liver gene expression Bltp3a 0.34 0.09 0.0e+00 0.26 0.21 0.23 0.25 1.8e-28 1.9e-22 1.3e-25 9.3e-28
10 NAcc gene expression Bltp3a 0.01 0.01 7.8e-03 0.01 0.01 0 0.01 6.4e-03 1.7e-02 4.7e-02 8.9e-03
11 IC gene expression Bltp3a 0.09 0.06 5.4e-03 0.06 0.06 0.05 0.06 1.2e-03 2.2e-03 2.9e-03 2.1e-03
12 Adipose mRNA stability Bltp3a 0.42 0.1 0.0e+00 0.1 0.14 0.19 0.19 2.6e-11 1.7e-15 3.5e-20 3.6e-20
13 Brain gene expression Bltp3a 0.07 0.05 1.3e-05 0.04 0.04 0.04 0.04 4.5e-05 9.7e-05 1.3e-04 7.9e-05
14 Adipose isoform ratio XM_039099274.2 0.27 0.09 1.7e-16 0.1 0.1 0.12 0.12 2.1e-11 1.3e-11 1.0e-13 9.5e-13
15 PL gene expression Bltp3a 0.08 0.04 1.3e-07 0.07 0.08 0.07 0.07 1.4e-08 9.5e-09 4.0e-08 3.9e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.00.00.10.10.2-0.20.10.3-0.4-0.0-0.10.10.3-0.2-0.1-0.20.30.0
Area under the delay curve0.10.10.50.00.3-0.7-0.30.1-0.50.5-0.30.3-0.30.1-0.50.30.30.0
BMI with tail1.96.512.03.53.41.03.43.30.1-1.0-3.23.23.32.0-1.01.82.7-1.7
BMI without tail0.63.06.52.62.30.72.42.00.3-0.6-2.22.22.01.6-1.21.31.8-0.9
Body weight1.87.919.20.91.4-3.61.51.52.33.4-2.62.62.53.6-4.43.22.9-3.2
Weight adjusted by age0.41.05.3-0.5-0.2-2.3-0.7-0.30.12.3-0.20.2-0.30.0-1.80.00.7-0.3
Bone surface0.30.72.1-1.3-0.9-1.5-0.7-0.71.01.10.7-0.7-0.20.2-0.70.3-0.3-0.5
Bone volume0.10.20.9-0.4-0.1-0.9-0.2-0.00.30.70.0-0.00.20.3-0.60.30.2-0.4
Breakpoint value in progressive ratio session0.40.82.30.80.70.81.00.91.1-0.3-1.01.00.21.5-0.21.00.8-1.0
Number of licking bursts0.31.02.0-1.4-1.20.2-1.0-1.31.1-0.51.2-1.2-0.8-0.50.6-0.9-1.40.1
Context. condit. distance diff. score2.22.77.3-2.7-2.2-1.0-2.2-2.10.80.32.0-2.0-1.9-0.80.9-0.5-2.00.1
Locomotion velocity, session 12.22.44.0-1.7-1.9-0.4-2.0-1.9-0.80.41.9-1.9-1.7-1.80.5-1.8-1.41.5
Locomotion distance, session 12.02.65.9-0.8-1.11.1-1.1-1.1-1.3-1.41.8-1.8-1.3-2.32.0-2.4-1.72.0
Locomotion velocity, session 20.80.92.1-1.5-1.4-0.0-1.1-1.30.70.01.3-1.3-1.0-0.50.5-0.4-1.20.2
Locomotion distance, session 20.60.91.7-0.9-0.90.1-1.0-0.8-0.8-0.31.1-1.1-0.8-1.31.0-1.2-0.91.0
Locomotion velocity, session 30.80.92.3-0.2-0.41.2-0.4-0.6-0.4-1.20.9-0.9-0.9-1.11.5-0.9-1.31.0
Locomotion distance, session 31.92.14.4-0.5-0.71.7-0.9-0.9-1.0-2.01.3-1.3-1.5-2.02.1-1.6-1.71.6
Stereotopy head waving bouts, day 30.91.03.1-1.3-0.9-1.6-0.7-0.81.81.30.4-0.4-0.41.0-1.00.9-0.3-1.1
Stereotopy head waving duration, day 30.40.51.4-1.0-0.9-1.1-0.9-0.90.51.20.6-0.6-0.70.2-0.60.2-0.3-0.1
Locomotion velocity, session 70.70.82.2-0.8-0.4-0.6-1.1-0.5-1.50.10.8-0.8-1.0-1.40.8-1.1-0.60.9
Locomotion distance, session 71.62.14.1-1.1-0.9-0.4-1.6-1.1-2.0-0.21.4-1.4-1.6-2.01.6-1.6-1.31.8
Stereotopy head waving bouts, day 70.20.31.60.3-0.31.3-0.1-0.4-0.3-0.80.3-0.3-0.6-0.50.3-0.3-0.30.8
Stereotopy head waving duration, day 70.10.11.10.50.11.00.3-0.00.2-0.7-0.10.1-0.1-0.1-0.2-0.00.00.2
Locomotion velocity, session 82.93.59.6-3.1-2.6-1.9-2.5-2.51.41.52.1-2.1-2.0-0.3-0.3-0.2-1.7-0.1
Locomotion distance, session 82.33.37.6-2.8-2.2-0.6-2.3-2.10.3-0.12.3-2.3-2.0-1.51.6-1.1-2.30.6
Degree of sensitization distance1.31.47.4-0.8-0.3-2.7-0.3-0.00.82.4-0.20.20.41.2-1.21.10.5-1.1
Degree of sensitization stereotypy0.91.04.30.5-0.22.1-0.1-0.3-0.8-1.70.5-0.5-0.7-1.21.2-0.9-0.71.3
Conditioned locomotion1.92.25.70.10.7-1.40.90.91.81.3-1.31.31.42.2-1.42.41.1-2.3
Cocaine response after cond. corrected0.50.71.80.30.8-0.11.00.91.00.1-0.80.81.31.0-0.50.80.7-1.3
Cocaine response after cond. not corrected0.30.42.2-0.4-0.0-0.60.30.01.50.4-0.10.10.70.8-0.60.7-0.0-1.1
Cocaine response before conditioning1.11.32.9-1.5-1.6-1.2-1.4-1.70.71.01.3-1.3-1.1-0.5-0.3-0.2-1.40.4
Saline control response2.83.97.32.72.40.42.52.4-0.30.3-2.42.42.31.6-1.61.82.6-0.9
Bone: connectivity density0.10.21.5-0.5-0.1-1.2-0.1-0.00.20.8-0.00.00.50.0-0.70.10.3-0.5
Bone: cortical apparent density0.81.22.51.61.51.11.61.5-0.1-1.1-1.21.21.40.50.10.50.9-0.4
Bone: cortical area0.00.10.4-0.1-0.1-0.2-0.1-0.20.10.20.2-0.20.1-0.3-0.0-0.7-0.30.2
Bone: cortical porosity1.31.54.9-0.1-0.80.6-1.2-0.9-2.1-0.41.0-1.0-1.6-1.50.9-1.2-0.82.2
Bone: cortical porosity1.31.53.7-0.6-1.1-0.5-1.6-1.2-1.80.61.0-1.0-1.7-1.40.1-1.2-0.71.9
Bone: cortical thickness1.22.05.01.91.32.21.41.1-1.6-2.1-0.50.50.9-1.31.6-1.6-0.11.4
Bone: cortical thickness2.02.45.72.42.21.02.42.2-0.6-1.1-1.71.72.20.50.40.41.1-0.3
Bone: cortical tissue density0.61.02.01.41.40.91.41.30.0-0.9-1.11.11.30.5-0.10.60.9-0.5
Condit. Reinf. active minus inactive responses0.30.41.4-0.1-0.2-0.9-0.6-0.3-1.20.70.4-0.4-0.4-0.6-0.4-0.40.10.9
Condit. Reinf. active-inactive response ratio0.60.61.21.00.9-0.20.80.9-0.20.4-0.90.91.00.7-1.00.81.1-0.3
Condit. Reinf. active responses0.20.31.20.20.4-1.1-0.10.2-0.90.8-0.20.20.2-0.2-0.6-0.00.50.3
Condit. Reinf. inactive responses0.10.20.70.40.6-0.30.20.5-0.8-0.1-0.30.30.3-0.50.3-0.40.10.2
Incentive salience index mean0.60.71.6-1.1-0.9-1.3-1.2-1.0-0.50.90.9-0.9-0.9-0.7-0.3-0.7-0.50.6
Condit. Reinf. lever presses0.71.13.1-1.8-1.3-1.4-1.5-1.30.50.91.1-1.1-1.1-0.4-0.2-0.8-0.9-0.1
Condit. Reinf. active minus inactive responses0.50.71.3-0.9-1.0-0.6-1.1-1.0-0.50.61.0-1.0-1.1-0.60.4-0.4-0.80.8
Condit. Reinf. active-inactive response ratio0.30.40.8-0.8-0.8-0.8-0.9-0.9-0.00.70.7-0.7-0.8-0.2-0.1-0.1-0.60.4
Condit. Reinf. active responses0.50.71.1-0.9-1.0-0.5-1.0-0.9-0.60.41.0-1.0-1.0-0.60.7-0.5-0.80.9
Condit. Reinf. inactive responses0.00.00.2-0.00.0-0.10.10.2-0.20.10.0-0.00.00.10.50.1-0.10.1
Condit. Reinf. lever presses1.01.53.4-0.6-1.10.4-1.2-1.1-1.6-0.41.2-1.2-1.3-1.61.0-1.3-1.01.8
Condit. Reinf. lever reinforcers received0.81.11.6-1.0-1.2-0.4-1.3-1.2-0.80.21.3-1.3-1.2-1.00.9-0.9-1.11.2
Conditioned reinforcement - actives0.00.20.6-0.3-0.3-0.8-0.4-0.3-0.50.1-0.40.4-0.0-0.2-0.5-0.70.30.1
Conditioned reinforcement - inactives0.10.41.30.0-0.20.3-0.5-0.4-1.1-0.70.4-0.4-0.6-0.80.4-0.5-0.41.1
Conditioned locomotion0.50.74.3-0.30.3-2.1-0.60.1-0.71.3-0.60.6-0.4-0.1-1.40.20.8-0.1
Patch foraging indifference point 0 sec0.61.74.62.01.40.61.81.6-0.3-0.3-1.61.62.10.8-0.30.61.3-0.4
Patch foraging indifference point AUC0.51.32.8-1.7-1.5-0.7-1.2-1.61.10.41.6-1.6-0.8-0.7-0.1-0.4-1.50.2
Delay disc. indifference point, 0s delay0.10.10.4-0.5-0.2-0.6-0.5-0.3-0.10.30.2-0.2-0.4-0.1-0.2-0.3-0.1-0.1
Delay disc. indifference point, 16s delay0.20.32.20.40.20.4-0.20.1-1.5-0.6-0.10.1-0.2-0.40.6-0.50.01.0
Delay disc. indifference point, 2s delay0.40.41.5-0.7-0.6-1.2-1.0-0.6-0.31.20.3-0.3-0.8-0.5-0.6-0.2-0.10.2
Delay disc. indifference point, 24s delay0.30.53.10.90.9-0.4-0.00.6-1.80.2-0.60.6-0.2-0.1-0.20.10.60.8
Delay disc. indifference point, 4s delay0.30.41.1-0.10.3-0.8-0.00.10.70.7-0.30.30.00.6-1.01.00.3-0.8
Delay disc. indifference point, 8s delay0.20.30.80.20.4-0.9-0.20.3-0.70.8-0.60.6-0.10.3-0.80.70.6-0.1
Indifference point function ln k0.20.51.4-0.5-0.80.6-0.6-0.8-0.3-0.60.6-0.6-0.9-0.61.2-0.9-0.90.7
Indifference point function log k0.20.51.4-0.5-0.80.6-0.6-0.8-0.3-0.60.6-0.6-0.9-0.61.2-0.9-0.90.7
Patch foraging total patch changes 0 sec0.61.74.52.11.50.81.91.6-0.6-0.5-1.61.62.10.6-0.20.41.3-0.2
Patch foraging total patch changes 12 sec0.20.31.10.70.21.00.80.30.1-0.8-0.20.20.9-0.20.3-0.20.00.2
Patch foraging total patch changes 18 sec0.92.16.61.91.70.72.21.90.1-0.8-1.51.52.60.8-0.30.91.3-0.8
Patch foraging total patch changes 24 sec0.41.32.91.71.41.21.41.4-1.3-1.3-0.90.91.6-0.30.6-0.10.80.5
Patch foraging total patch changes 6 sec0.91.64.12.01.71.41.61.6-1.1-1.2-1.21.21.60.00.20.61.00.3
Patch foraging time to switch 0 sec1.14.28.42.52.70.82.62.9-0.1-0.4-2.62.62.11.9-0.61.82.5-1.5
Patch foraging water rate 0 sec0.10.30.8-0.5-0.8-0.4-0.6-0.9-0.20.20.5-0.5-0.0-0.8-0.2-0.8-0.50.5
Patch foraging water rate 12 sec0.20.83.00.3-0.11.40.1-0.1-0.8-1.70.5-0.5-0.0-1.01.6-0.8-0.81.0
Patch foraging water rate 18 sec0.10.20.60.50.6-0.60.40.3-0.00.4-0.70.70.70.2-0.80.20.4-0.4
Patch foraging water rate 24 sec0.40.62.7-0.0-0.21.40.0-0.30.1-1.60.4-0.4-0.2-0.71.4-0.7-1.10.4
Patch foraging water rate 6 sec0.30.41.0-0.2-0.30.7-0.1-0.4-0.2-0.90.7-0.7-0.1-0.61.0-0.7-0.80.6
Seeking ratio, delayed vs. immediate footshock0.30.42.10.10.00.70.70.21.4-0.50.1-0.10.60.90.10.8-0.3-0.8
Distance traveled before self-admin0.30.63.7-0.4-0.2-0.00.30.01.90.5-0.10.10.31.1-0.31.20.1-1.3
Distance traveled after self-admin0.71.25.4-0.2-0.2-0.40.60.22.30.9-0.40.40.71.9-0.91.40.6-1.7
Extensor digitorum longus weight0.52.15.7-2.4-2.2-1.3-1.9-1.91.11.41.5-1.5-1.3-0.2-0.6-0.4-0.9-0.2
Bone: elastic displacement0.81.05.00.5-0.10.7-0.5-0.3-2.2-0.60.4-0.4-0.8-1.60.5-1.0-0.11.9
Bone: elastic work0.20.32.00.80.50.10.10.3-1.40.1-0.30.30.0-0.5-0.4-0.30.60.8
Bone: endosteal estimation2.45.816.8-1.7-0.7-4.1-0.6-0.63.44.0-0.40.40.32.9-3.62.60.9-3.0
Bone: endosteal perimeter1.23.08.2-1.6-0.7-2.7-0.6-0.72.92.40.0-0.00.02.1-2.32.00.2-2.4
Epididymis fat weight4.522.753.77.36.94.86.56.4-2.6-4.9-5.05.05.61.21.31.73.8-0.5
Delta time in closed arm before/after self-admin0.70.71.71.31.20.20.81.1-1.0-0.4-1.11.10.30.6-0.30.20.90.1
Delta time in open arm before/after self-admin0.20.20.8-0.6-0.6-0.6-0.4-0.50.90.80.4-0.4-0.2-0.0-0.3-0.2-0.2-0.5
Diff in mean of infusions in LGA sessions0.10.20.70.30.60.80.50.60.1-0.8-0.40.40.10.30.40.60.2-0.4
Delay discount exponential model param0.10.10.5-0.0-0.20.70.4-0.10.6-0.50.2-0.20.40.00.5-0.3-0.2-0.1
Extinction: sum of active levers before priming0.10.10.70.0-0.20.80.0-0.20.1-0.60.1-0.1-0.2-0.10.5-0.3-0.20.2
Active lever presses in extinction session 60.80.83.01.31.1-0.30.51.0-1.70.4-1.11.10.20.2-0.7-0.11.30.6
Bone: final force2.64.27.22.22.5-0.32.52.50.70.6-2.52.52.72.2-1.41.82.2-1.9
Bone: final moment1.82.94.61.92.1-0.32.02.00.50.6-2.22.22.11.8-1.31.51.9-1.5
Food consumed during 24 hour testing period1.42.95.80.61.1-1.41.31.31.61.4-1.61.61.62.4-2.12.41.9-2.2
Glucose2.54.08.7-2.9-2.6-2.0-3.0-2.80.41.82.1-2.1-2.5-1.0-0.7-1.0-1.60.6
Heart weight1.21.94.7-0.6-1.3-0.5-1.5-1.4-2.00.41.1-1.1-1.2-1.90.3-2.1-0.72.2
Delay discount hyperbolic model param0.10.10.40.20.00.60.60.10.6-0.5-0.10.10.50.20.3-0.1-0.0-0.3
Intermittent access intake day 1-15 change0.10.82.40.70.90.41.00.91.20.2-0.90.90.71.5-0.21.20.5-1.2
Intermittent access intake escalation0.21.22.61.21.30.51.41.30.80.1-1.21.20.91.6-0.31.20.9-1.1
Intermittent access intake escalation 20.20.41.6-0.4-0.2-0.8-0.3-0.20.91.3-0.20.2-0.30.8-0.70.20.1-0.7
Intermitt. access day 1 inactive lever presses0.11.32.5-1.1-1.51.5-0.4-1.21.4-1.11.4-1.4-0.3-0.21.3-0.6-1.60.1
Intermitt. access day 15 inactive lever presses0.10.31.3-0.4-0.4-0.50.1-0.21.20.6-0.00.00.50.8-0.60.40.1-0.8
Intermitt. access escalation Index0.20.72.5-0.6-0.51.60.1-0.41.1-1.40.9-0.9-0.1-0.21.4-0.1-1.1-0.3
Intermittent access day 1 total infusions0.61.75.4-0.7-1.1-0.7-1.6-1.2-2.20.10.5-0.5-1.4-1.70.1-2.3-0.21.9
Intermittent access day 15 total infusions0.10.10.70.30.1-0.1-0.10.1-0.80.1-0.30.3-0.2-0.2-0.1-0.80.30.6
Intermittent access terminal intake (last 3 days)0.20.31.40.30.10.0-0.3-0.1-1.20.1-0.10.1-0.5-0.50.2-1.10.11.0
Intermittent access total infusions0.40.51.9-0.2-0.5-0.5-0.8-0.6-1.40.20.1-0.1-0.7-0.9-0.1-1.2-0.01.2
Intermittent access day 1 locomotion0.10.20.8-0.5-0.4-0.9-0.5-0.3-0.30.40.0-0.0-0.1-0.3-0.6-0.30.20.1
Intermittent access day 15 total locomotion0.41.73.90.41.0-1.80.50.90.61.6-1.41.40.61.6-2.01.71.5-1.4
Intermittent access total locomotion0.60.73.7-0.30.1-1.9-0.30.10.11.5-0.60.60.20.5-1.60.70.8-0.6
Intermittent access standard deviation0.31.83.81.51.30.31.71.40.90.1-1.61.61.61.9-0.71.41.3-1.2
Left kidney weight0.53.86.70.80.9-2.01.41.21.72.0-2.02.02.42.5-2.62.22.1-2.3
Right kidney weight0.96.512.20.61.3-2.91.61.62.52.8-2.32.32.53.5-3.53.12.6-3.3
Cocaine induced anxiety0.30.73.5-1.3-0.9-0.6-0.4-0.81.90.80.7-0.70.20.3-0.30.3-0.7-1.0
Post-drug Anxiety0.40.41.9-0.4-0.0-0.50.3-0.11.40.80.1-0.10.90.6-0.50.8-0.2-1.1
Baseline Anxiety0.81.33.41.81.80.91.41.6-1.0-0.9-1.31.31.10.50.30.61.0-0.1
Tail length0.94.712.4-2.7-2.3-3.5-2.1-2.42.63.51.4-1.4-1.31.1-2.70.9-0.7-1.1
Length with tail2.19.234.8-3.1-2.4-5.9-2.2-2.23.25.70.6-0.6-0.52.3-4.51.80.5-2.3
Length without tail1.26.524.5-1.1-0.2-4.9-0.20.02.24.6-1.21.21.42.5-4.22.32.0-2.9
Times rat made contact with spout0.80.93.11.20.61.60.50.6-1.8-1.3-0.20.20.2-1.00.7-0.80.41.3
Lifetime Intake0.30.41.70.0-0.2-0.6-0.6-0.3-1.30.3-0.10.1-0.6-0.6-0.3-0.90.31.0
Liver weight, left2.03.49.9-1.5-0.6-2.9-0.3-0.53.12.7-0.20.20.72.0-2.81.80.4-2.6
Liver weight, right2.95.112.2-3.2-2.2-3.5-2.0-2.13.53.01.3-1.3-1.01.5-2.41.7-0.8-2.1
Locomotor activity0.30.43.0-0.4-0.50.60.1-0.51.7-0.60.5-0.5-0.10.40.20.1-1.0-0.5
Locomotor testing distance0.20.61.80.50.61.11.00.61.3-1.4-0.30.30.60.70.30.5-0.3-0.8
Locomotor testing rearing0.31.34.00.30.8-0.21.10.92.0-0.1-0.90.91.31.5-0.51.70.3-1.9
Locomotion in novel chamber0.10.20.7-0.1-0.50.4-0.3-0.5-0.2-0.40.1-0.1-0.7-0.4-0.2-0.90.00.4
Locomotion in novel chamber post-restriction0.61.83.31.41.8-0.31.41.60.10.3-1.61.61.21.5-1.31.51.8-1.1
Fecal boli incidents, locomotor time 10.20.51.30.40.6-0.90.30.7-0.30.8-1.01.00.40.4-0.90.61.1-0.6
Change in fecal boli incidents, locomotor task0.10.10.40.20.4-0.10.40.40.70.1-0.10.10.50.5-0.20.7-0.1-0.5
Time >=10cm from walls, locomotor time 13.34.19.20.81.4-1.01.91.62.81.4-1.91.92.12.6-2.22.61.5-3.0
Bouts of movement, locomotor time 10.20.31.6-0.6-0.50.3-0.1-0.31.30.00.5-0.5-0.20.60.10.4-0.4-0.6
Total resting periods, locomotor time 10.30.41.8-0.8-0.6-0.3-0.3-0.41.30.60.5-0.5-0.10.6-0.40.6-0.3-0.8
Rest time, locomotor task time 10.61.02.2-1.5-1.1-0.8-1.5-1.3-0.10.61.2-1.2-1.2-1.10.3-0.7-1.10.5
Distance moved, locomotor task time 10.30.91.61.21.00.31.31.10.3-0.1-1.11.11.11.2-0.60.91.1-0.7
Vertical activity count, locomotor time 10.64.07.31.91.8-0.32.32.11.20.7-2.42.42.32.7-1.82.22.3-2.0
Time >=10cm from walls, locomotor time 21.33.85.91.62.2-1.61.62.00.71.5-2.32.31.52.1-2.42.32.3-2.0
Bouts of movement, locomotor time 20.30.93.4-1.2-0.7-0.8-0.5-0.71.81.00.9-0.9-0.50.9-0.91.2-0.5-1.0
Total resting periods, locomotor time 20.31.33.0-1.6-1.3-0.6-1.1-1.21.70.91.5-1.5-1.10.3-0.50.6-1.0-0.5
Rest time, locomotor task time 20.71.23.9-1.8-1.3-0.7-1.0-1.32.00.71.1-1.1-0.7-0.2-0.1-0.1-1.2-0.8
Distance moved, locomotor task time 22.43.26.42.22.3-0.91.72.2-1.20.8-2.42.41.81.5-1.51.52.5-0.7
Vertical activity count, locomotor time 21.22.75.51.61.8-1.41.31.8-0.71.2-2.12.11.71.5-1.81.62.4-1.0
Light reinforcement 10.83.66.91.31.70.12.32.02.1-0.4-1.91.92.62.5-1.52.01.8-2.5
Light reinforcement 21.32.86.20.41.1-1.11.31.31.90.9-1.51.51.82.3-1.92.51.6-2.5
Bone: marrow area2.56.017.0-1.6-0.6-4.1-0.5-0.53.44.0-0.50.50.43.0-3.72.71.0-3.1
Bone: maximum diameter1.12.35.6-2.4-1.8-2.3-1.8-1.81.61.91.4-1.4-1.10.1-1.0-0.1-1.1-0.6
Bone: maximum force0.50.91.60.81.0-0.81.01.00.40.9-1.11.11.31.0-1.10.51.1-1.0
Bone: maximum moment0.30.51.20.50.7-1.00.40.50.21.0-0.80.80.70.6-1.10.20.8-0.6
Mean time between licks in bursts1.05.914.9-3.9-3.5-1.1-3.1-3.31.40.73.0-3.0-2.8-0.91.1-1.0-2.80.4
Mean num. licks in bursts0.41.13.81.71.30.81.01.2-2.0-0.4-0.90.90.7-0.3-0.10.21.20.8
Cd content in liver1.41.64.01.01.4-1.20.91.4-0.81.1-1.51.51.30.7-1.50.82.0-0.8
Co content in liver3.54.17.22.52.7-0.42.32.6-0.40.4-2.62.62.51.5-1.51.62.5-1.4
Cu content in liver1.51.86.21.51.02.50.90.8-1.6-2.3-0.20.20.0-1.21.7-1.3-0.11.4
Fe content in liver0.30.40.70.50.6-0.30.60.80.00.5-0.70.70.70.8-0.10.60.7-0.6
K content in liver1.61.52.5-1.5-1.6-0.3-1.5-1.5-0.5-0.01.6-1.6-1.2-1.30.9-1.2-1.31.1
Mg content in liver2.22.46.4-2.5-2.3-1.1-1.8-2.00.90.72.1-2.1-1.0-0.80.5-0.5-1.90.2
Mn content in liver3.94.412.7-3.6-3.1-2.3-2.6-2.62.02.02.3-2.3-1.60.00.10.2-2.1-0.6
Na content in liver0.60.72.60.1-0.31.60.1-0.2-0.4-1.50.5-0.5-0.4-0.71.4-0.5-0.80.8
Rb content in liver0.50.62.2-0.10.3-1.50.20.30.31.1-0.50.50.80.5-1.40.70.9-0.9
Se content in liver5.26.112.1-3.4-3.5-1.0-3.2-3.40.60.93.1-3.1-2.9-1.51.2-1.6-2.91.3
Sr content in liver0.40.31.00.40.5-1.0-0.00.4-0.70.8-0.70.70.10.2-0.9-0.10.9-0.1
Zn content in liver1.11.32.8-1.7-1.5-1.1-1.6-1.4-0.21.01.3-1.3-1.1-0.8-0.1-0.8-0.80.6
Bone: minimum diameter1.01.86.3-1.2-0.6-2.5-0.5-0.61.92.2-0.00.00.31.4-2.01.10.3-1.6
Time in familiar zone, hab. session 10.50.62.70.80.61.00.20.5-1.6-0.8-0.20.2-0.0-0.81.0-0.50.11.0
Time in novel zone, hab. session 10.20.21.1-0.6-0.3-0.6-0.3-0.51.00.30.3-0.3-0.30.2-0.70.4-0.2-0.5
Total zone transitions, hab. session 12.13.06.6-0.4-0.92.1-0.7-1.1-0.9-2.41.6-1.6-1.2-2.32.3-2.6-2.02.0
Total locomotion distance, hab. session 12.12.95.3-1.1-1.31.4-1.1-1.3-0.7-1.92.0-2.0-1.3-2.22.3-2.3-2.11.8
Locomotion velocity, hab. session 12.02.95.9-1.1-1.51.3-1.1-1.3-0.8-1.61.9-1.9-1.3-2.02.3-2.4-2.01.9
Time in familiar zone, hab. session 20.40.41.7-0.3-0.31.00.4-0.11.3-1.10.4-0.40.20.31.1-0.1-0.8-0.4
Time in novel zone, hab. session 20.91.03.30.60.7-1.5-0.00.5-1.21.5-0.80.80.30.1-1.80.41.40.1
Total zone transitions, hab. session 20.81.03.4-0.5-0.41.5-0.0-0.50.7-1.80.9-0.9-0.3-0.91.6-1.1-1.50.3
Total locomotion distance, hab. session 21.82.35.8-1.0-1.12.0-0.5-0.90.5-2.41.6-1.6-0.7-1.42.3-1.9-2.00.8
Locomotion velocity, hab. session 22.43.27.4-1.3-1.42.1-0.8-1.30.3-2.51.9-1.9-1.1-1.82.7-2.2-2.41.2
Novel to familiar place preference ratio0.20.31.60.70.40.40.20.3-1.3-0.2-0.40.40.0-0.50.0-0.60.60.8
Novelty place preference0.20.21.20.50.20.30.00.1-1.1-0.1-0.20.2-0.1-0.5-0.0-0.60.40.7
Time in novel zone, NPP test0.10.10.90.40.20.1-0.00.1-1.00.1-0.20.2-0.1-0.4-0.2-0.40.50.6
Total zone transitions, NPP test1.62.44.1-1.3-1.40.9-1.3-1.4-0.6-1.21.9-1.9-1.3-2.01.8-2.0-1.91.5
Total locomotion distance, NPP test0.60.82.4-0.5-0.40.4-0.6-0.4-1.0-0.80.9-0.9-0.3-1.41.1-1.5-0.81.0
Locomotion velocity, NPP test0.91.23.1-0.4-0.51.1-0.5-0.4-1.1-1.41.0-1.0-0.4-1.71.7-1.8-1.11.2
Intraocular pressure0.20.30.9-0.10.3-0.90.20.30.30.6-0.30.30.70.7-0.80.50.7-0.7
Delta distance traveled before/after self-admin0.20.20.80.40.0-0.70.20.1-0.10.7-0.40.40.10.5-0.90.00.8-0.1
Delta ambulatory time before/after self-admin0.20.30.90.1-0.0-0.80.30.10.60.8-0.40.40.40.7-1.00.30.6-0.6
Parametrial fat weight2.96.811.71.92.4-0.32.82.72.40.3-3.03.03.13.4-2.23.32.6-3.3
Pavlov. Cond. lever latency4.76.010.12.62.80.33.23.01.2-0.1-2.82.83.12.7-1.52.82.6-2.3
Pavlov. Cond. magazine entry latency3.64.68.3-2.7-2.7-0.9-2.8-2.9-0.10.62.8-2.8-2.5-1.90.8-1.8-2.51.6
Pavlov. Cond. change in total contacts1.01.12.2-1.1-1.2-0.5-1.5-1.5-0.30.31.2-1.2-1.4-1.10.1-1.0-1.21.0
Pavlov. Cond. index score4.55.710.0-2.8-2.9-0.7-3.2-3.1-0.70.52.9-2.9-3.0-2.41.1-2.4-2.62.0
Pavlov. Cond. latency score4.25.49.5-2.7-2.8-0.7-3.1-3.0-0.60.52.8-2.8-2.9-2.21.1-2.3-2.61.9
Pavlov. Cond. lever contacts3.23.97.1-2.2-2.2-0.6-2.7-2.4-0.90.32.2-2.2-2.5-2.10.9-2.3-2.01.8
Pavlov. Cond. magazine entry number3.14.06.82.32.40.42.52.60.2-0.1-2.62.62.22.0-1.11.92.5-1.6
Pavlov. Cond. intertrial magazine entries1.31.63.71.71.9-0.61.41.8-1.50.2-1.51.51.40.2-0.60.41.60.0
Pavlov. Cond. lever-magazine prob. diff.4.65.79.6-2.6-2.8-0.6-3.1-3.0-0.90.32.8-2.8-2.9-2.51.2-2.5-2.62.1
Pavlov. Cond. response bias4.75.810.0-2.9-3.0-0.8-3.1-3.2-0.30.43.0-3.0-2.8-2.41.1-2.3-2.81.9
Pavlov. Cond. lever latency0.81.13.70.10.6-0.40.90.71.90.3-0.90.90.91.6-0.91.40.6-1.9
Pavlov. Cond. magazine entry latency0.40.62.8-0.5-0.2-1.6-0.6-0.20.01.7-0.10.1-0.30.6-1.20.60.5-0.4
Pavlov. Cond. change in total contacts0.20.41.90.1-0.30.1-0.5-0.3-1.40.20.4-0.4-0.6-0.70.3-0.7-0.01.2
Pavlov. Cond. index score0.30.51.1-0.4-0.6-0.6-0.9-0.6-1.10.80.6-0.6-0.8-0.6-0.2-0.5-0.10.9
Pavlov. Cond. latency score0.20.30.9-0.4-0.5-0.4-0.8-0.5-0.90.70.5-0.5-0.8-0.5-0.2-0.4-0.00.8
Pavlov. Cond. lever contacts0.60.83.30.1-0.40.4-0.6-0.4-1.8-0.20.6-0.6-0.6-1.40.8-1.2-0.41.7
Pavlov. Cond. magazine entry number0.30.31.1-0.2-0.40.8-0.1-0.40.2-1.00.5-0.5-0.2-0.61.0-0.5-0.80.4
Pavlov. Cond. intertrial magazine entries0.81.84.2-2.0-1.8-0.1-1.1-1.52.1-0.21.6-1.6-1.00.01.10.2-2.0-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-0.3-0.5-0.6-0.8-0.5-1.00.80.4-0.4-0.7-0.5-0.2-0.40.00.8
Pavlov. Cond. response bias0.60.82.2-0.5-0.7-0.7-1.1-0.8-1.50.60.9-0.9-0.9-1.20.3-1.0-0.41.4
Time in closed arm before self-admin0.00.00.2-0.3-0.1-0.5-0.3-0.10.00.40.0-0.0-0.2-0.30.10.1-0.0-0.1
Time in closed arm after self-admin0.50.63.60.70.60.3-0.10.4-1.9-0.7-0.20.2-0.4-0.90.6-0.80.21.2
Time in open arm before self-admin0.50.61.7-0.3-0.80.6-0.8-0.7-0.80.10.8-0.8-1.0-0.70.6-1.1-0.51.3
Time in open arm after self-admin0.50.51.3-1.0-1.2-0.4-0.8-1.00.81.00.8-0.8-0.7-0.20.0-0.5-0.5-0.0
Bone: periosteal estimation0.92.16.4-1.1-0.5-2.5-0.4-0.52.32.5-0.10.10.31.7-2.21.30.4-1.8
Bone: periosteal perimeter0.30.62.1-0.6-0.3-1.1-0.2-0.31.41.1-0.10.10.31.0-1.20.90.1-1.1
Bone: post-yield work1.01.77.9-1.4-0.7-2.8-0.9-0.71.42.50.1-0.1-0.31.0-1.7-0.00.1-1.3
Progressive ratio test 1 active lever presses0.10.21.60.30.2-0.5-0.30.0-1.3-0.2-0.40.4-0.5-0.4-0.3-0.30.40.7
Progressive ratio test 1 breakpoint0.10.31.70.20.1-0.4-0.4-0.1-1.3-0.2-0.30.3-0.5-0.5-0.3-0.40.30.8
Progressive ratio test 1 inactive lever presses0.30.81.61.21.10.71.11.1-0.3-1.0-1.11.11.10.7-0.10.60.9-0.3
Progressive ratio test 2 active lever presses0.10.20.80.20.20.2-0.3-0.0-0.9-0.7-0.00.0-0.6-0.50.3-0.5-0.10.7
Progressive ratio test 2 breakpoint0.20.20.90.20.20.2-0.3-0.0-1.0-0.7-0.00.0-0.6-0.50.3-0.6-0.10.8
Progressive ratio test 2 inactive lever presses0.20.61.4-0.8-0.7-0.9-1.2-0.9-0.60.30.6-0.6-0.9-0.8-0.0-0.9-0.70.7
Incentive Sensitization - Responses0.20.71.5-0.6-0.71.0-0.6-0.80.0-1.00.8-0.8-0.9-0.61.0-1.2-1.00.7
Incentive Sensitization - Breakpoint0.20.51.0-0.4-0.51.0-0.4-0.60.1-1.00.6-0.6-0.7-0.40.9-1.0-0.80.5
Sum of active levers in priming session hrs 5-60.10.10.4-0.1-0.40.1-0.4-0.3-0.5-0.00.3-0.3-0.6-0.20.3-0.5-0.20.6
Progressive ratio1.02.86.21.81.80.22.11.91.30.2-1.91.91.92.1-0.72.51.2-1.7
Food seeking constrained by brief footshock0.40.52.01.20.9-0.00.40.8-1.40.1-0.90.90.1-0.1-0.30.00.80.7
Seeking ratio, punishment vs. effort0.92.14.8-0.8-1.10.4-1.6-1.3-2.0-0.61.3-1.3-1.7-2.10.8-2.2-0.82.1
Retroperitoneal fat weight0.21.12.90.71.1-0.61.01.10.70.1-1.01.01.11.3-0.91.71.1-1.2
Reaction time number correct0.62.04.42.12.11.32.01.9-0.2-1.1-1.61.61.11.00.51.41.0-0.6
Reaction time mean minus median0.53.27.6-2.7-2.2-2.7-2.1-2.11.82.61.4-1.4-1.20.6-1.60.3-0.8-0.9
Reaction time mean minus median AUC0.42.88.7-2.4-1.8-3.0-2.2-1.80.82.81.0-1.0-1.40.5-1.70.3-0.3-0.5
Reaction time num false alarms0.60.93.1-1.5-1.8-0.1-0.8-1.41.20.11.2-1.2-0.4-0.10.5-0.6-1.20.0
Reaction time num false alarms AUC0.71.54.3-1.7-2.10.1-1.1-1.81.1-0.11.5-1.5-0.7-0.60.8-1.1-1.60.4
Reaction time trials correct on left0.62.04.42.12.11.32.01.9-0.2-1.1-1.61.61.11.00.51.41.0-0.6
Reaction time trials on left0.61.94.22.02.11.21.91.9-0.1-1.0-1.61.61.11.10.41.41.0-0.7
Reaction time mean1.02.18.4-1.7-1.1-2.9-1.4-1.01.32.80.3-0.3-0.51.0-2.10.40.2-1.2
Reaction time mean AUC0.92.28.8-1.5-0.8-3.0-1.2-0.81.32.80.1-0.1-0.41.2-2.30.70.4-1.4
Median of all reaction times0.81.35.7-1.0-0.4-2.4-0.7-0.40.92.2-0.20.2-0.11.0-1.80.50.5-1.2
Reaction time omissions0.81.45.3-1.7-1.1-1.4-0.8-1.02.31.00.6-0.6-0.21.0-1.01.1-0.5-1.5
Reaction time false alarm rate2.63.69.6-2.7-3.1-0.5-2.2-2.70.80.42.4-2.4-1.5-1.30.6-1.9-2.11.0
Reaction time premature initiation rate0.10.10.40.30.10.30.30.20.0-0.2-0.30.30.70.2-0.60.10.7-0.1
Reaction time premature initiations0.41.32.51.61.40.91.51.5-0.0-0.6-1.41.41.40.9-0.51.01.4-0.6
Std. dev. reaction times1.13.79.9-2.8-2.3-3.1-2.3-2.21.73.21.4-1.4-1.20.6-2.00.1-0.7-0.8
Reaction time trials completed0.61.94.22.02.11.21.91.9-0.1-1.0-1.61.61.11.10.41.41.0-0.7
Reaction time trials AUC0.62.04.52.02.11.22.01.9-0.1-0.9-1.61.61.21.10.41.51.0-0.8
Run reversals in cocaine runway, females0.50.63.60.90.6-0.20.10.5-1.9-0.0-0.80.8-0.1-0.3-0.1-0.51.00.9
Run reversals in cocaine runway, males1.61.84.6-2.1-1.7-1.9-1.7-1.71.01.31.4-1.4-1.3-0.5-0.8-0.3-1.0-0.1
Latency to leave start box in cocaine runway0.20.31.0-0.1-0.30.6-0.3-0.4-0.5-0.40.5-0.5-0.1-0.71.0-0.9-0.80.7
Latency to leave start box in cocaine runway, F0.10.20.8-0.1-0.30.3-0.2-0.2-0.3-0.20.3-0.30.0-0.50.9-0.8-0.60.4
Latency to leave start box in cocaine runway, M0.10.10.30.2-0.00.50.0-0.1-0.2-0.20.2-0.2-0.1-0.40.5-0.2-0.50.5
Std. dev. time between licks in bursts2.54.811.4-3.4-3.0-0.7-2.8-3.01.30.22.8-2.8-2.6-1.11.1-0.9-2.60.5
Total sessions with >9 infusions0.20.20.8-0.1-0.4-0.4-0.5-0.4-0.80.00.0-0.0-0.5-0.4-0.4-0.90.30.8
Short access day 1 total inactive lever presses0.50.92.4-0.9-1.0-1.6-1.3-1.1-0.31.50.5-0.5-1.3-0.2-0.8-0.9-0.20.5
Short access day 10 total inactive lever presses0.21.24.9-0.3-0.62.00.7-0.32.2-1.40.7-0.70.80.81.20.4-1.1-0.8
Short access day 1 total infusions0.30.61.7-0.5-1.0-0.6-1.1-0.9-1.10.00.4-0.4-1.0-0.7-0.1-1.3-0.21.2
Short access day 10 total infusions0.00.00.10.1-0.2-0.0-0.1-0.1-0.4-0.2-0.30.3-0.20.1-0.2-0.30.30.3
Short access total infusions0.20.31.50.1-0.2-0.5-0.5-0.2-1.20.0-0.20.2-0.6-0.4-0.4-1.00.40.9
Short access day 1 locomotion0.20.41.1-0.4-0.80.8-0.4-0.60.2-1.10.7-0.7-0.6-0.20.7-0.4-0.70.5
Short access day 10 total locomotion0.10.63.1-1.0-1.1-0.3-0.3-0.91.80.40.6-0.60.00.7-0.70.5-0.4-0.7
Short access total locomotion0.10.20.6-0.5-0.5-0.5-0.1-0.30.80.30.1-0.10.10.6-0.70.30.1-0.5
One hour access (0.3 mA shock)1.61.93.4-1.2-1.61.0-1.3-1.5-0.3-0.81.5-1.5-1.5-1.41.5-1.9-1.61.2
Compulsive drug intake0.60.92.4-1.3-1.50.6-0.6-1.11.60.20.9-0.9-0.80.30.8-0.8-1.0-0.5
One hour access (shock baseline)0.20.51.7-0.2-0.2-0.7-0.8-0.5-1.30.10.4-0.4-0.6-1.2-0.2-0.7-0.21.1
Social response proportion0.10.20.8-0.5-0.6-0.7-0.3-0.40.40.90.2-0.20.20.0-0.40.00.0-0.2
Social responses0.10.21.1-0.4-0.50.10.0-0.31.1-0.20.3-0.30.00.30.10.2-0.5-0.4
Social time1.82.812.3-2.6-2.3-0.6-1.1-1.93.50.41.6-1.6-0.80.80.10.1-1.8-1.4
Soleus weight2.67.719.7-4.4-3.7-3.7-3.5-3.52.43.42.6-2.6-2.40.2-2.00.2-1.6-0.8
Bone: stiffness0.61.13.00.81.1-0.41.41.20.90.3-1.11.11.71.2-0.70.60.9-1.3
Tibialis anterior weight0.00.21.0-0.0-0.31.00.10.0-0.2-0.70.3-0.30.1-0.30.4-0.50.10.3
Time to tail flick, vehicle, before self-admin1.21.57.6-0.60.10.30.80.32.8-0.10.1-0.11.31.80.61.9-0.6-2.2
Time to tail flick, vehicle, after self-admin0.10.20.6-0.5-0.4-0.5-0.3-0.30.60.80.2-0.2-0.20.2-0.5-0.1-0.1-0.3
Time to tail flick, test, before self-admin0.50.62.8-0.0-0.21.70.2-0.10.3-1.40.7-0.7-0.3-0.31.2-0.4-0.90.4
Time to tail flick, test, after self-admin0.70.72.2-0.9-0.70.4-1.0-0.7-0.10.01.2-1.2-1.5-0.60.9-0.3-1.00.7
Delta time to tail flick, vehicle, before/after SA1.11.16.30.80.3-0.2-0.50.1-2.50.1-0.30.3-0.8-1.4-0.6-1.60.71.8
Delta time to tail flick, test, before/after SA0.10.10.50.40.6-0.10.20.5-0.3-0.1-0.40.40.10.30.00.70.3-0.2
Tibia length1.43.912.9-1.3-0.3-3.0-0.0-0.33.62.7-0.40.40.52.6-2.32.40.1-2.9
Ambulatory time before self-admin0.10.21.0-0.2-0.30.50.1-0.11.00.00.1-0.1-0.30.60.30.5-0.1-0.4
Ambulatory time after self-admin0.40.62.9-0.1-0.3-0.30.40.01.70.7-0.30.30.31.4-0.60.90.5-1.1
Bone: tissue strength0.40.41.00.81.0-0.20.50.7-0.30.3-1.01.00.30.3-0.80.21.0-0.4
Total heroin consumption0.20.32.0-0.2-0.40.80.3-0.11.4-0.10.2-0.20.00.80.30.2-0.2-0.6
Bone: trabecular number0.10.10.60.10.10.00.10.2-0.7-0.30.0-0.00.2-0.50.3-0.60.20.4
Bone: trabecular spacing0.50.71.90.60.6-0.30.50.50.80.9-0.90.90.31.3-1.31.40.9-0.9
Bone: trabecular thickness0.30.42.1-0.10.3-1.40.20.50.01.0-0.40.40.70.5-0.70.40.6-0.7
Bone: trabecular tissue density0.40.71.7-0.7-1.0-0.2-1.2-1.1-0.40.50.9-0.9-1.3-0.70.2-0.7-0.80.9
Water consumed over 24 hours0.00.10.4-0.2-0.10.1-0.1-0.20.4-0.30.2-0.20.1-0.2-0.6-0.00.0-0.2
Number of responses in last shaping day2.53.37.2-1.2-1.8-0.2-2.3-2.0-1.9-0.21.5-1.5-2.7-2.21.0-2.4-1.52.5