Hub : Genes

Bloc1s1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Bloc1s1 0.44 0.18 1.1e-07 0.28 0.27 0.29 0.28 1.9e-07 3.7e-07 1.2e-07 1.8e-07
2 NAcc mRNA stability Bloc1s1 0.09 0.05 3.8e-11 0.07 0.07 0.07 0.07 2.9e-11 8.9e-11 5.3e-11 3.9e-11
3 PL gene expression Bloc1s1 0.07 0.05 1.1e-05 0.05 0.04 0.04 0.04 4.9e-06 1.5e-05 2.5e-05 1.0e-05
4 Eye intron excision ratio chr7_1932787_1934691 0.29 0.18 8.8e-03 0.14 0.1 0.1 0.13 3.5e-03 1.1e-02 1.2e-02 5.6e-03
5 OFC gene expression Bloc1s1 0.25 0.14 7.2e-04 0.14 0.12 0.13 0.14 3.2e-04 7.9e-04 5.4e-04 3.8e-04
6 Brain mRNA stability Bloc1s1 0.34 0.16 0.0e+00 0.21 0.2 0.21 0.21 4.3e-19 9.7e-19 5.4e-19 2.4e-19
7 IL gene expression Bloc1s1 0.22 0.14 5.0e-03 0.07 0.02 0.03 0.04 1.0e-02 1.1e-01 6.7e-02 3.3e-02
8 PL mRNA stability Bloc1s1 0.24 0.13 0.0e+00 0.18 0.17 0.17 0.18 1.2e-19 1.3e-18 9.5e-19 2.6e-19
9 OFC mRNA stability Bloc1s1 0.2 0.12 1.9e-03 0.1 0.09 0.11 0.09 2.8e-03 3.4e-03 1.3e-03 3.1e-03
10 pVTA mRNA stability Bloc1s1 0.08 0.05 2.3e-05 0.04 0.05 0.03 0.05 6.1e-04 4.1e-05 1.3e-03 1.3e-04
11 Liver gene expression Bloc1s1 0.08 0.06 3.5e-06 0.03 0.04 0.06 0.04 2.1e-04 2.8e-05 3.5e-07 2.4e-05
12 IL mRNA stability Bloc1s1 0.49 0.18 3.9e-07 0.17 0.17 0.18 0.18 5.5e-05 6.1e-05 3.7e-05 4.5e-05
13 Brain gene expression Bloc1s1 0.1 0.06 4.8e-07 0.05 0.06 0.07 0.06 1.8e-05 1.8e-06 8.9e-07 2.7e-06
14 BLA gene expression Bloc1s1 0.14 0.08 1.7e-07 0.14 0.11 0.11 0.12 1.2e-07 1.9e-06 1.7e-06 1.1e-06
15 pVTA isoform ratio XM_063263093.1 0.03 0.02 8.4e-03 0.03 0.02 0.03 0.03 1.6e-03 6.9e-03 3.4e-03 3.7e-03
16 pVTA intron excision ratio chr7_1934763_1935447 0.04 0.03 6.9e-04 0.01 0.01 0.01 0.02 2.5e-02 2.8e-02 2.9e-02 1.4e-02
17 LHb gene expression Bloc1s1 0.16 0.11 8.4e-03 0.09 0.09 0.09 0.09 3.3e-03 4.1e-03 3.0e-03 4.6e-03
18 Adipose gene expression Bloc1s1 0.05 0.04 1.5e-05 0.01 0.02 0.03 0.03 1.6e-02 1.1e-03 1.2e-04 5.1e-04
19 BLA mRNA stability Bloc1s1 0.49 0.3 5.5e-08 0.13 0.13 0.15 0.14 2.5e-07 2.6e-07 2.6e-08 9.4e-08
20 NAcc gene expression Bloc1s1 0.04 0.02 1.0e-04 0.02 0.02 0.02 0.02 9.2e-04 3.0e-04 1.1e-03 1.6e-03
21 Adipose mRNA stability Bloc1s1 0.07 0.05 8.3e-06 0.02 0.05 0.05 0.05 1.1e-03 5.9e-06 3.5e-06 5.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.61.24.2-0.3-1.21.21.21.20.70.9-1.20.10.1-0.2-0.90.2-0.7-0.6-0.61.6-1.8-0.5-1.8-2.1
Area under the delay curve0.20.32.8-0.9-0.70.50.50.50.60.6-0.7-0.50.40.2-0.40.3-0.1-0.1-0.10.10.2-1.7-0.5-0.3
BMI with tail7.727.033.5-5.6-5.65.55.55.55.85.5-5.6-5.75.75.6-5.55.65.35.35.34.64.0-2.4-4.1-3.7
BMI without tail1.26.68.8-2.8-2.92.82.82.83.02.6-2.9-2.82.82.7-2.62.82.62.72.72.22.0-1.2-1.9-1.7
Body weight1.35.68.0-2.8-2.52.52.52.52.82.4-2.5-2.72.62.5-2.32.62.42.62.61.52.3-1.8-1.4-1.1
Weight adjusted by age0.00.10.20.20.2-0.3-0.3-0.3-0.2-0.30.30.2-0.2-0.00.30.0-0.1-0.2-0.2-0.4-0.1-0.00.40.4
Bone surface0.91.810.40.7-0.70.70.70.7-0.00.4-0.71.0-0.7-1.0-0.5-0.6-1.6-1.5-1.51.8-3.20.5-2.1-2.5
Bone volume1.01.99.00.3-1.11.11.11.10.40.8-1.10.6-0.3-0.7-0.9-0.2-1.3-1.3-1.32.1-3.00.2-2.4-2.8
Breakpoint value in progressive ratio session0.81.52.31.41.5-1.5-1.5-1.5-1.4-1.31.51.2-1.2-1.21.2-1.2-1.0-1.0-1.0-1.0-0.31.11.11.0
Number of licking bursts1.13.44.8-2.2-1.91.91.91.92.11.8-1.9-2.22.12.1-1.72.12.12.02.01.12.1-1.3-0.9-0.6
Context. condit. distance diff. score0.20.20.4-0.5-0.40.40.40.40.50.6-0.4-0.60.60.5-0.60.50.60.50.50.40.4-0.1-0.4-0.4
Locomotion velocity, session 10.70.73.0-0.8-0.90.90.90.90.61.0-0.9-0.40.50.1-0.80.2-0.3-0.2-0.21.0-0.9-1.7-1.5-1.4
Locomotion distance, session 10.30.42.60.3-0.10.10.10.1-0.30.2-0.10.5-0.4-0.6-0.1-0.6-1.0-0.9-0.90.6-1.6-0.6-1.0-1.1
Locomotion velocity, session 21.21.55.51.30.8-0.8-0.8-0.8-1.2-0.80.81.4-1.3-1.40.7-1.4-1.7-1.8-1.80.0-2.30.3-0.4-0.6
Locomotion distance, session 21.92.66.71.31.1-1.1-1.1-1.1-1.5-1.11.11.8-1.8-2.11.3-1.9-2.5-2.5-2.5-0.8-2.6-1.00.0-0.0
Locomotion velocity, session 34.45.16.22.22.5-2.4-2.4-2.4-2.5-2.32.52.4-2.4-2.42.4-2.4-2.4-2.3-2.3-2.3-1.60.31.81.8
Locomotion distance, session 30.10.10.20.20.4-0.3-0.3-0.3-0.3-0.30.40.3-0.3-0.20.4-0.3-0.2-0.2-0.2-0.5-0.1-0.10.40.4
Stereotopy head waving bouts, day 35.36.38.52.72.6-2.5-2.5-2.5-2.7-2.72.62.9-2.9-2.82.6-2.8-2.8-2.7-2.7-2.0-2.31.11.71.5
Stereotopy head waving duration, day 34.15.17.82.82.3-2.3-2.3-2.3-2.5-2.52.32.6-2.5-2.32.3-2.4-2.2-2.3-2.3-1.6-2.12.01.61.3
Locomotion velocity, session 70.10.10.40.30.3-0.2-0.2-0.2-0.4-0.00.30.2-0.2-0.20.1-0.4-0.4-0.5-0.50.1-0.70.2-0.2-0.3
Locomotion distance, session 70.10.10.6-0.2-0.00.00.00.00.20.1-0.0-0.40.30.4-0.10.30.60.50.5-0.20.80.10.40.4
Stereotopy head waving bouts, day 70.70.82.20.60.5-0.5-0.5-0.5-0.8-0.50.51.0-0.9-1.20.6-1.1-1.4-1.3-1.3-0.2-1.5-0.7-0.3-0.3
Stereotopy head waving duration, day 70.60.72.80.50.3-0.3-0.3-0.3-0.7-0.30.30.9-0.8-1.20.4-1.0-1.5-1.3-1.3-0.0-1.7-0.9-0.6-0.6
Locomotion velocity, session 80.91.14.30.50.3-0.4-0.4-0.4-0.7-0.40.31.1-1.0-1.40.5-1.1-1.8-1.7-1.7-0.1-2.1-1.3-0.6-0.6
Locomotion distance, session 80.20.40.90.30.4-0.4-0.4-0.4-0.5-0.30.40.6-0.6-0.80.4-0.6-1.0-0.9-0.9-0.4-0.9-0.70.00.0
Degree of sensitization distance0.60.60.9-0.8-0.90.90.90.90.90.9-0.9-0.90.90.8-0.90.80.80.70.70.80.5-0.3-0.7-0.6
Degree of sensitization stereotypy0.30.41.5-0.7-0.60.60.60.60.40.8-0.6-0.40.40.1-0.60.2-0.2-0.1-0.10.7-0.4-1.2-1.0-1.0
Conditioned locomotion0.81.03.3-1.2-0.60.60.60.60.90.7-0.6-1.21.11.2-0.61.01.31.51.5-0.11.8-0.80.20.4
Cocaine response after cond. corrected1.31.94.0-1.5-1.21.21.21.21.51.2-1.2-1.71.61.8-1.21.71.91.71.70.62.0-0.4-0.3-0.1
Cocaine response after cond. not corrected1.32.04.5-1.4-1.11.11.11.11.41.1-1.1-1.71.61.9-1.11.72.11.91.90.62.10.0-0.1-0.0
Cocaine response before conditioning0.50.60.91.00.8-0.8-0.8-0.8-0.9-0.90.81.0-0.9-0.80.8-0.8-0.7-0.6-0.6-0.4-0.70.90.50.3
Saline control response0.60.81.6-1.1-0.90.90.90.91.00.7-0.9-0.90.91.0-0.61.01.01.21.20.21.3-0.8-0.1-0.0
Bone: connectivity density0.30.52.1-0.0-0.80.80.80.80.40.4-0.80.2-0.0-0.1-0.50.1-0.5-0.5-0.51.1-1.5-0.0-1.2-1.4
Bone: cortical apparent density0.81.31.8-0.9-1.21.21.21.21.21.3-1.2-1.21.21.2-1.31.21.21.01.01.30.80.4-1.0-1.0
Bone: cortical area0.91.54.5-0.6-1.41.41.41.41.01.3-1.4-0.70.80.7-1.50.80.30.30.32.0-0.80.4-1.9-2.1
Bone: cortical porosity0.10.10.60.4-0.00.00.00.0-0.10.1-0.00.1-0.10.0-0.20.0-0.1-0.2-0.20.6-0.70.8-0.5-0.7
Bone: cortical porosity0.30.31.50.2-0.40.40.40.40.20.4-0.4-0.00.20.3-0.60.3-0.0-0.1-0.11.1-1.01.0-1.0-1.2
Bone: cortical thickness1.42.34.9-1.0-1.71.71.71.71.51.7-1.7-1.31.41.4-1.91.41.11.11.12.20.20.5-1.9-2.0
Bone: cortical thickness0.60.81.6-0.9-0.80.80.80.80.90.9-0.8-1.11.01.0-0.80.91.11.11.10.61.3-0.2-0.3-0.2
Bone: cortical tissue density0.60.91.3-0.8-1.01.01.01.01.01.1-1.0-1.01.01.0-1.11.01.00.80.81.10.70.4-0.9-0.9
Condit. Reinf. active minus inactive responses2.12.33.21.71.6-1.6-1.6-1.6-1.7-1.51.61.6-1.7-1.51.5-1.6-1.5-1.8-1.8-1.2-1.41.01.10.9
Condit. Reinf. active-inactive response ratio0.60.61.81.00.9-0.9-0.9-0.9-0.8-0.90.90.7-0.7-0.30.8-0.5-0.2-0.5-0.5-0.7-0.21.30.90.8
Condit. Reinf. active responses2.63.36.02.01.8-1.7-1.7-1.7-2.0-1.71.82.0-2.0-2.01.6-2.0-2.2-2.4-2.4-1.1-2.20.80.80.6
Condit. Reinf. inactive responses1.11.43.61.10.9-0.8-0.8-0.8-1.2-0.80.91.4-1.3-1.60.9-1.4-1.9-1.8-1.8-0.5-1.9-0.30.0-0.1
Incentive salience index mean1.11.43.01.21.1-1.0-1.0-1.0-1.3-0.91.11.3-1.3-1.41.0-1.3-1.6-1.7-1.7-0.6-1.70.20.30.2
Condit. Reinf. lever presses0.40.62.8-0.0-0.10.10.10.1-0.30.3-0.10.4-0.4-0.8-0.1-0.6-1.3-1.2-1.20.4-1.7-1.5-1.0-1.0
Condit. Reinf. active minus inactive responses2.33.64.92.02.2-2.2-2.2-2.2-2.0-2.22.21.9-1.9-1.62.2-1.8-1.2-1.3-1.3-2.1-0.51.42.22.1
Condit. Reinf. active-inactive response ratio0.91.43.90.81.4-1.4-1.4-1.4-1.1-1.31.40.7-0.8-0.61.4-0.8-0.1-0.2-0.2-1.70.70.61.92.0
Condit. Reinf. active responses1.92.84.02.01.8-1.8-1.8-1.8-1.8-2.01.81.9-1.8-1.51.8-1.7-1.4-1.4-1.4-1.4-1.21.51.51.3
Condit. Reinf. inactive responses0.30.51.51.00.5-0.5-0.5-0.5-0.7-0.70.51.0-0.9-0.80.6-0.7-0.9-0.8-0.8-0.1-1.20.70.1-0.0
Condit. Reinf. lever presses2.73.95.42.12.1-2.1-2.1-2.1-2.0-2.32.12.1-2.1-2.02.3-2.0-1.6-1.5-1.5-2.1-0.71.22.12.1
Condit. Reinf. lever reinforcers received1.62.23.31.71.7-1.7-1.7-1.7-1.6-1.81.71.6-1.6-1.31.7-1.4-1.1-1.0-1.0-1.4-0.81.41.51.4
Conditioned reinforcement - actives0.10.68.01.20.4-0.5-0.5-0.5-0.4-0.70.20.5-0.40.30.30.10.20.20.20.2-0.52.80.30.1
Conditioned reinforcement - inactives0.30.79.40.80.2-0.3-0.3-0.30.0-0.50.0-0.10.20.90.00.71.10.80.80.30.53.10.50.2
Conditioned locomotion3.34.817.13.32.1-2.3-2.3-2.3-2.3-2.52.02.5-2.3-1.61.9-1.9-1.5-1.8-1.8-0.8-2.24.11.30.8
Patch foraging indifference point 0 sec1.95.37.5-1.9-2.52.52.52.52.42.4-2.5-2.32.42.5-2.62.52.22.42.42.71.10.2-2.2-2.3
Patch foraging indifference point AUC0.40.91.30.81.0-1.0-1.0-1.0-1.0-1.01.00.8-1.0-1.01.0-1.0-0.9-1.0-1.0-1.1-0.50.10.91.0
Delay disc. indifference point, 0s delay3.03.36.1-2.0-2.32.22.22.21.92.2-2.3-1.51.51.1-2.01.30.40.60.61.9-0.3-2.5-2.5-2.3
Delay disc. indifference point, 16s delay0.10.10.50.10.3-0.3-0.3-0.3-0.4-0.10.30.3-0.3-0.40.2-0.5-0.4-0.6-0.6-0.3-0.3-0.70.00.1
Delay disc. indifference point, 2s delay0.80.92.6-1.2-1.21.11.11.11.01.2-1.2-0.80.80.3-1.00.60.00.10.10.90.1-1.6-1.1-1.1
Delay disc. indifference point, 24s delay0.40.72.8-1.2-0.90.80.80.80.91.0-1.0-0.90.80.6-0.70.70.50.50.50.40.5-1.7-0.7-0.5
Delay disc. indifference point, 4s delay0.20.31.00.0-0.10.10.10.1-0.10.0-0.10.4-0.4-0.70.1-0.5-0.9-0.8-0.80.1-1.0-1.0-0.5-0.4
Delay disc. indifference point, 8s delay0.20.31.4-0.9-0.60.40.40.40.70.4-0.6-0.60.60.5-0.30.60.30.40.4-0.20.8-1.20.00.3
Indifference point function ln k0.00.11.00.20.0-0.0-0.0-0.00.0-0.00.0-0.10.20.3-0.20.10.30.50.50.40.21.0-0.0-0.2
Indifference point function log k0.00.11.00.20.0-0.0-0.0-0.00.0-0.00.0-0.10.20.3-0.20.10.30.50.50.40.21.0-0.0-0.2
Patch foraging total patch changes 0 sec1.64.66.6-1.8-2.32.32.32.32.32.2-2.3-2.22.32.3-2.52.32.12.32.32.61.10.3-2.0-2.2
Patch foraging total patch changes 12 sec1.62.13.2-1.5-1.51.51.51.51.71.4-1.5-1.61.61.7-1.41.81.71.71.71.11.4-0.1-0.8-0.7
Patch foraging total patch changes 18 sec0.00.10.2-0.4-0.30.30.30.30.30.4-0.3-0.30.30.1-0.30.30.10.10.10.20.0-0.5-0.4-0.3
Patch foraging total patch changes 24 sec0.20.81.2-1.0-1.01.11.11.11.01.1-1.0-0.80.90.6-1.00.80.60.60.61.00.4-0.8-1.0-1.0
Patch foraging total patch changes 6 sec1.42.43.4-1.2-1.71.71.71.71.61.6-1.7-1.51.61.8-1.71.71.61.51.51.80.60.4-1.5-1.6
Patch foraging time to switch 0 sec0.20.81.5-0.9-1.21.21.21.21.01.0-1.2-0.50.60.6-0.80.80.30.30.31.0-0.4-0.9-1.2-1.2
Patch foraging water rate 0 sec0.10.62.1-0.6-0.40.40.40.40.60.4-0.4-1.00.81.0-0.50.81.21.21.20.21.50.40.20.2
Patch foraging water rate 12 sec0.20.82.7-0.6-0.40.40.40.40.70.5-0.4-1.01.01.2-0.61.01.41.41.40.41.60.70.10.1
Patch foraging water rate 18 sec0.51.04.20.30.9-0.9-0.9-0.9-0.4-0.80.9-0.10.00.30.80.10.90.80.8-1.22.11.01.81.9
Patch foraging water rate 24 sec1.41.99.9-1.2-0.40.40.40.41.10.5-0.4-1.61.41.7-0.51.52.22.22.2-0.33.10.31.01.2
Patch foraging water rate 6 sec1.21.84.01.41.6-1.6-1.6-1.6-1.3-1.61.60.8-0.9-0.51.3-0.80.10.00.0-1.41.02.02.01.9
Seeking ratio, delayed vs. immediate footshock1.31.83.41.81.2-1.3-1.3-1.3-1.5-1.41.11.6-1.5-1.71.2-1.5-1.4-1.4-1.4-0.6-1.11.60.70.5
Distance traveled before self-admin0.81.72.21.31.5-1.4-1.4-1.4-1.5-1.31.41.3-1.4-1.51.3-1.4-1.4-1.4-1.4-1.1-0.80.31.00.9
Distance traveled after self-admin0.00.11.0-0.3-0.20.20.20.20.20.1-0.2-0.10.0-0.10.00.0-0.20.20.2-0.20.1-1.0-0.00.1
Extensor digitorum longus weight4.618.424.8-4.6-4.44.44.44.44.84.2-4.4-4.84.84.9-4.24.95.04.94.93.34.3-1.4-2.5-2.2
Bone: elastic displacement0.00.00.10.10.1-0.1-0.1-0.1-0.1-0.00.1-0.00.00.0-0.10.00.10.10.10.2-0.00.3-0.1-0.1
Bone: elastic work1.01.31.9-1.1-1.31.31.31.31.21.3-1.3-1.01.10.9-1.31.00.70.80.81.40.2-0.6-1.3-1.4
Bone: endosteal estimation0.40.92.2-0.6-1.11.11.11.10.91.1-1.1-0.70.80.8-1.20.90.60.60.61.5-0.20.5-1.3-1.4
Bone: endosteal perimeter0.30.72.81.00.5-0.5-0.5-0.5-0.8-0.60.51.1-1.0-1.00.5-0.9-1.2-1.2-1.20.1-1.70.8-0.2-0.4
Epididymis fat weight0.10.41.60.20.6-0.7-0.7-0.7-0.3-0.60.60.2-0.3-0.20.7-0.20.10.10.1-1.10.80.11.11.3
Delta time in closed arm before/after self-admin1.31.25.8-0.4-0.20.20.20.20.70.1-0.2-1.01.01.3-0.31.22.01.71.7-0.12.41.50.80.9
Delta time in open arm before/after self-admin1.41.64.7-1.8-1.41.41.41.41.41.5-1.4-1.41.30.9-1.11.10.71.11.10.60.9-2.2-0.9-0.7
Diff in mean of infusions in LGA sessions1.52.63.61.81.8-1.8-1.8-1.8-1.8-1.81.91.7-1.7-1.51.8-1.7-1.3-1.4-1.4-1.5-1.01.11.51.3
Delay discount exponential model param0.20.32.70.80.5-0.4-0.4-0.4-0.4-0.50.60.4-0.3-0.00.3-0.20.20.20.2-0.0-0.21.60.40.2
Extinction: sum of active levers before priming1.32.03.11.41.7-1.7-1.7-1.7-1.6-1.61.71.3-1.4-1.11.7-1.3-0.8-1.0-1.0-1.8-0.20.81.71.7
Active lever presses in extinction session 60.20.20.50.50.4-0.4-0.4-0.4-0.5-0.30.40.5-0.5-0.40.3-0.4-0.6-0.7-0.7-0.1-0.70.10.1-0.0
Bone: final force3.04.98.3-1.9-2.72.72.72.72.32.6-2.7-1.92.01.8-2.61.91.31.41.42.90.1-0.6-2.8-2.9
Bone: final moment3.04.98.2-1.9-2.72.72.72.72.32.6-2.7-1.92.01.8-2.51.91.31.41.42.90.1-0.6-2.7-2.8
Food consumed during 24 hour testing period0.20.50.7-0.8-0.80.80.80.80.80.8-0.8-0.80.80.7-0.70.70.70.60.60.60.6-0.3-0.6-0.5
Glucose1.72.74.1-2.0-1.81.81.81.81.81.8-1.8-1.81.81.5-1.61.71.41.61.61.21.4-1.6-1.2-1.0
Heart weight0.40.61.20.80.9-1.0-1.0-1.0-0.8-0.90.90.6-0.7-0.50.8-0.5-0.2-0.3-0.3-1.00.10.81.01.1
Delay discount hyperbolic model param0.40.63.21.00.9-0.8-0.8-0.8-0.8-0.90.90.7-0.6-0.30.7-0.50.0-0.0-0.0-0.4-0.21.80.80.6
Intermittent access intake day 1-15 change0.42.18.12.01.6-1.8-1.8-1.8-1.4-1.81.71.2-1.2-0.71.4-0.8-0.3-0.3-0.3-1.00.12.91.51.4
Intermittent access intake escalation0.31.97.11.81.5-1.7-1.7-1.7-1.3-1.71.61.1-1.1-0.61.4-0.7-0.2-0.2-0.2-1.00.22.71.51.4
Intermittent access intake escalation 20.91.52.71.61.4-1.5-1.5-1.5-1.3-1.51.51.1-1.1-0.91.3-0.8-0.7-0.5-0.5-1.0-0.01.61.31.1
Intermitt. access day 1 inactive lever presses0.11.33.31.01.4-1.4-1.4-1.4-1.0-1.51.30.7-0.8-0.21.4-0.60.1-0.0-0.0-1.60.51.21.81.8
Intermitt. access day 15 inactive lever presses0.21.21.91.11.3-1.4-1.4-1.4-1.2-1.31.31.1-1.1-0.91.3-1.0-0.8-1.0-1.0-1.2-0.40.31.11.1
Intermitt. access escalation Index0.10.30.9-0.1-0.60.60.60.60.30.5-0.5-0.10.2-0.0-0.60.1-0.3-0.2-0.20.8-0.6-0.0-0.9-0.9
Intermittent access day 1 total infusions0.10.21.70.1-0.20.20.20.20.20.1-0.5-0.20.30.6-0.20.40.70.50.50.30.21.3-0.1-0.0
Intermittent access day 15 total infusions0.20.67.41.20.5-0.6-0.6-0.6-0.5-0.70.30.5-0.40.10.3-0.10.20.00.00.2-0.22.70.30.1
Intermittent access terminal intake (last 3 days)0.30.55.41.30.5-0.6-0.6-0.6-0.6-0.60.30.7-0.6-0.20.3-0.3-0.3-0.3-0.30.4-0.82.30.0-0.2
Intermittent access total infusions0.30.34.80.70.0-0.1-0.1-0.1-0.1-0.2-0.20.1-0.00.4-0.10.30.40.20.20.6-0.32.2-0.1-0.3
Intermittent access day 1 locomotion0.10.21.00.20.2-0.3-0.3-0.3-0.1-0.30.1-0.10.10.50.20.20.70.60.6-0.30.41.00.50.6
Intermittent access day 15 total locomotion0.41.711.71.91.4-1.5-1.5-1.5-1.2-1.61.21.0-0.9-0.31.1-0.6-0.0-0.1-0.1-0.6-0.23.41.31.0
Intermittent access total locomotion0.40.53.31.10.7-0.8-0.8-0.8-0.6-0.90.50.6-0.6-0.20.7-0.3-0.0-0.1-0.1-0.4-0.21.80.80.6
Intermittent access standard deviation0.42.311.02.31.5-1.7-1.7-1.7-1.6-1.61.41.6-1.5-1.01.2-1.2-0.9-1.1-1.1-0.4-1.43.30.80.4
Left kidney weight0.00.10.6-0.4-0.20.10.10.10.20.1-0.1-0.30.20.1-0.00.00.10.20.2-0.30.4-0.70.10.3
Right kidney weight0.10.51.50.30.7-0.7-0.7-0.7-0.6-0.70.80.5-0.6-0.60.9-0.8-0.5-0.6-0.6-1.20.0-0.70.91.1
Cocaine induced anxiety0.51.53.31.20.9-0.9-0.9-0.9-1.2-0.90.91.5-1.4-1.81.0-1.5-1.8-1.8-1.8-0.4-1.60.20.1-0.0
Post-drug Anxiety0.70.82.50.90.2-0.3-0.3-0.3-0.6-0.30.21.0-0.9-1.60.3-1.0-1.5-1.6-1.60.5-1.30.2-0.6-0.8
Baseline Anxiety0.00.00.1-0.0-0.20.10.10.10.20.1-0.2-0.10.10.0-0.10.10.10.10.10.20.30.1-0.1-0.1
Tail length2.312.616.23.63.8-3.8-3.8-3.8-3.8-3.93.83.9-3.9-3.74.0-3.8-3.5-3.3-3.3-3.7-2.31.33.33.2
Length with tail1.46.18.52.42.8-2.8-2.8-2.8-2.6-2.82.82.6-2.6-2.42.9-2.4-2.0-2.0-2.0-2.9-1.01.12.72.6
Length without tail0.10.61.3-0.9-0.70.60.60.60.80.7-0.6-1.00.91.0-0.70.91.11.11.10.41.1-0.3-0.2-0.1
Times rat made contact with spout1.11.22.2-1.2-1.01.01.01.01.21.1-1.0-1.31.31.5-1.01.41.41.41.40.61.1-0.4-0.5-0.3
Lifetime Intake0.60.77.90.6-0.30.20.20.20.30.2-0.7-0.20.40.9-0.60.80.80.70.71.2-0.22.8-0.6-0.8
Liver weight, left0.40.71.1-1.0-0.90.90.90.90.91.0-0.9-1.01.00.9-0.90.90.90.90.90.60.8-0.7-0.6-0.4
Liver weight, right0.10.21.3-0.20.1-0.2-0.2-0.2-0.0-0.20.20.1-0.2-0.20.4-0.1-0.2-0.1-0.1-0.80.3-1.10.50.7
Locomotor activity2.43.86.11.91.9-1.9-1.9-1.9-2.2-1.81.92.3-2.2-2.41.9-2.3-2.5-2.2-2.2-1.4-2.3-0.21.00.8
Locomotor testing distance0.82.03.11.61.3-1.4-1.4-1.4-1.6-1.31.31.7-1.6-1.71.3-1.7-1.7-1.7-1.7-0.9-1.70.30.60.5
Locomotor testing rearing0.00.00.2-0.10.2-0.2-0.2-0.2-0.0-0.20.20.0-0.00.00.20.00.10.30.3-0.30.2-0.40.30.4
Locomotion in novel chamber0.10.11.70.3-0.1-0.0-0.0-0.00.0-0.0-0.1-0.00.10.3-0.20.20.40.20.20.40.01.3-0.1-0.2
Locomotion in novel chamber post-restriction1.85.37.92.22.5-2.5-2.5-2.5-2.5-2.22.42.4-2.5-2.82.4-2.6-2.5-2.5-2.5-2.2-1.20.51.91.8
Fecal boli incidents, locomotor time 10.41.02.2-1.3-0.80.80.80.81.00.9-0.8-1.21.11.1-0.71.01.21.21.20.31.5-1.1-0.2-0.0
Change in fecal boli incidents, locomotor task0.50.62.40.70.4-0.4-0.4-0.4-0.7-0.40.40.9-0.8-0.90.4-0.9-1.2-1.1-1.10.1-1.5-0.0-0.4-0.5
Time >=10cm from walls, locomotor time 10.70.82.2-0.7-1.01.11.11.10.81.0-1.1-0.60.70.7-1.00.60.30.30.31.3-0.6-0.4-1.4-1.5
Bouts of movement, locomotor time 10.60.81.11.01.0-0.9-0.9-0.9-0.9-1.11.01.0-1.0-0.71.0-0.9-0.8-0.7-0.7-0.9-0.60.90.90.8
Total resting periods, locomotor time 11.31.51.81.31.3-1.2-1.2-1.2-1.3-1.41.31.3-1.4-1.21.3-1.4-1.2-1.1-1.1-1.2-0.90.71.11.0
Rest time, locomotor task time 10.20.40.90.50.5-0.4-0.4-0.4-0.6-0.50.50.8-0.8-0.90.6-0.9-1.0-0.8-0.8-0.4-0.9-0.40.10.1
Distance moved, locomotor task time 10.31.02.8-0.6-1.11.01.01.00.91.1-1.1-0.70.80.8-1.20.80.50.30.31.5-0.5-0.1-1.6-1.7
Vertical activity count, locomotor time 10.10.92.1-0.6-0.80.70.70.70.80.9-0.9-1.01.11.3-1.11.21.41.11.11.10.70.8-0.7-0.8
Time >=10cm from walls, locomotor time 20.30.91.5-0.8-0.80.80.80.81.00.8-0.9-1.11.11.2-0.91.11.21.21.20.71.20.2-0.3-0.3
Bouts of movement, locomotor time 20.10.21.70.40.0-0.0-0.0-0.0-0.2-0.20.10.5-0.4-0.30.1-0.5-0.7-0.6-0.60.3-1.30.3-0.5-0.6
Total resting periods, locomotor time 20.10.32.20.4-0.10.00.00.0-0.2-0.1-0.00.5-0.4-0.30.0-0.5-0.8-0.7-0.70.4-1.50.2-0.6-0.7
Rest time, locomotor task time 20.10.20.70.0-0.20.20.20.2-0.00.1-0.20.3-0.2-0.3-0.0-0.3-0.7-0.6-0.60.3-0.8-0.6-0.5-0.5
Distance moved, locomotor task time 20.10.10.40.10.3-0.3-0.3-0.3-0.1-0.20.3-0.10.10.30.20.20.50.40.4-0.30.50.70.50.5
Vertical activity count, locomotor time 20.41.03.1-0.9-0.60.60.60.60.90.7-0.6-1.21.21.3-0.81.31.81.41.40.31.60.20.00.1
Light reinforcement 11.56.89.63.12.8-2.9-2.9-2.9-2.9-2.82.82.9-2.9-2.72.6-2.7-2.7-2.6-2.6-1.8-2.32.11.81.4
Light reinforcement 20.71.52.31.51.3-1.3-1.3-1.3-1.3-1.41.31.5-1.4-1.21.3-1.3-1.2-0.9-0.9-0.9-1.01.21.00.7
Bone: marrow area0.30.81.9-0.5-1.01.01.01.00.91.0-1.0-0.70.80.8-1.10.80.60.60.61.4-0.20.5-1.2-1.3
Bone: maximum diameter0.51.03.91.30.5-0.5-0.5-0.5-0.9-0.60.51.2-1.1-1.10.5-1.1-1.3-1.4-1.40.3-2.01.2-0.4-0.6
Bone: maximum force2.65.17.9-2.1-2.72.72.72.72.42.6-2.7-2.02.11.9-2.62.01.41.61.62.80.4-0.8-2.7-2.7
Bone: maximum moment2.75.17.8-2.1-2.72.72.72.72.42.6-2.7-2.02.11.9-2.62.11.51.61.62.80.4-0.8-2.6-2.7
Mean time between licks in bursts0.31.62.81.61.5-1.5-1.5-1.5-1.4-1.41.51.3-1.3-1.11.2-1.2-1.0-1.0-1.0-1.0-0.71.71.11.1
Mean num. licks in bursts0.30.71.01.00.9-0.9-0.9-0.9-0.9-0.80.91.0-0.9-0.80.8-0.8-0.8-0.7-0.7-0.5-1.00.70.40.3
Cd content in liver0.50.61.71.00.9-0.8-0.8-0.8-0.9-0.80.90.8-0.8-0.70.7-0.7-0.5-0.7-0.7-0.4-0.61.30.50.4
Co content in liver2.93.44.41.92.1-2.1-2.1-2.1-2.0-2.12.11.9-1.9-1.72.0-1.8-1.5-1.5-1.5-1.9-0.81.21.91.8
Cu content in liver0.40.52.00.1-0.50.50.50.50.30.6-0.5-0.30.40.5-0.90.30.20.00.01.3-0.81.0-1.2-1.4
Fe content in liver0.10.10.5-0.1-0.10.10.10.10.20.2-0.1-0.40.40.6-0.30.40.70.60.60.20.40.7-0.0-0.0
K content in liver0.70.71.91.00.6-0.7-0.7-0.7-0.8-0.80.61.1-1.0-1.00.7-0.9-1.1-1.0-1.0-0.2-1.40.70.1-0.0
Mg content in liver0.91.01.71.10.8-0.9-0.9-0.9-1.0-1.00.81.3-1.2-1.21.0-1.1-1.3-1.3-1.3-0.7-1.30.30.50.4
Mn content in liver1.51.77.61.30.6-0.7-0.7-0.7-1.1-0.70.61.6-1.4-1.50.7-1.4-2.0-1.9-1.90.2-2.80.4-0.6-0.9
Na content in liver0.20.30.8-0.5-0.60.50.50.50.50.6-0.6-0.40.40.1-0.60.4-0.20.30.30.7-0.3-0.7-0.8-0.9
Rb content in liver0.40.41.70.1-0.50.60.60.60.30.5-0.5-0.00.20.3-0.70.20.1-0.2-0.21.2-0.90.9-1.2-1.3
Se content in liver0.00.00.10.00.1-0.1-0.1-0.1-0.1-0.10.10.2-0.1-0.00.1-0.0-0.2-0.0-0.0-0.1-0.3-0.20.10.1
Sr content in liver0.60.52.80.90.8-0.8-0.8-0.8-0.7-0.80.80.6-0.6-0.30.7-0.5-0.1-0.2-0.2-0.60.11.70.90.8
Zn content in liver3.54.07.21.92.3-2.3-2.3-2.3-2.0-2.42.31.8-1.9-1.52.3-1.7-1.1-1.3-1.3-2.5-0.01.32.72.7
Bone: minimum diameter0.30.51.8-0.1-0.80.80.80.80.50.7-0.8-0.20.30.2-0.80.30.0-0.1-0.11.3-0.80.6-1.2-1.3
Time in familiar zone, hab. session 13.94.35.71.92.3-2.3-2.3-2.3-2.2-2.32.32.1-2.2-2.22.4-2.2-1.9-1.9-1.9-2.4-1.00.22.12.1
Time in novel zone, hab. session 13.23.66.1-1.6-2.22.22.22.22.02.1-2.2-1.71.81.7-2.21.81.31.31.32.50.1-0.4-2.4-2.4
Total zone transitions, hab. session 10.40.52.40.20.0-0.0-0.0-0.0-0.3-0.10.00.7-0.6-0.90.2-0.6-1.3-1.3-1.30.1-1.6-1.0-0.6-0.7
Total locomotion distance, hab. session 11.42.07.61.20.7-0.7-0.7-0.7-1.2-0.80.71.6-1.5-1.80.8-1.5-2.2-2.3-2.3-0.1-2.8-0.2-0.5-0.7
Locomotion velocity, hab. session 11.52.16.21.41.0-1.0-1.0-1.0-1.4-1.01.01.7-1.6-1.81.1-1.6-2.2-2.2-2.2-0.4-2.5-0.0-0.1-0.2
Time in familiar zone, hab. session 25.15.87.72.52.8-2.8-2.8-2.8-2.6-2.82.82.4-2.5-2.22.7-2.4-1.8-1.9-1.9-2.7-0.81.32.72.6
Time in novel zone, hab. session 25.66.18.2-2.4-2.82.82.82.82.62.8-2.8-2.42.52.2-2.82.41.81.81.82.90.6-1.2-2.8-2.8
Total zone transitions, hab. session 21.11.44.4-0.9-1.31.31.31.30.91.4-1.3-0.70.80.5-1.40.6-0.00.10.11.7-1.0-1.0-2.0-2.1
Total locomotion distance, hab. session 20.30.41.80.20.1-0.1-0.1-0.1-0.4-0.00.10.5-0.5-0.80.1-0.6-1.1-1.0-1.00.1-1.4-0.9-0.6-0.6
Locomotion velocity, hab. session 20.40.62.70.20.0-0.0-0.0-0.0-0.40.10.00.6-0.6-0.90.1-0.6-1.3-1.2-1.20.2-1.6-1.1-0.8-0.8
Novel to familiar place preference ratio2.73.55.9-1.8-2.22.22.22.21.92.2-2.2-1.71.81.5-2.21.81.11.11.12.40.1-1.0-2.4-2.4
Novelty place preference1.82.34.3-1.4-1.71.71.71.71.51.8-1.7-1.31.41.2-1.81.40.80.80.82.0-0.0-0.7-2.1-2.1
Time in novel zone, NPP test2.32.84.8-1.5-1.91.91.91.91.72.0-1.9-1.51.61.4-2.01.61.11.01.02.20.2-0.6-2.2-2.2
Total zone transitions, NPP test0.81.23.1-1.2-1.31.31.31.31.11.3-1.3-0.90.90.6-1.10.80.10.30.31.1-0.3-1.8-1.5-1.4
Total locomotion distance, NPP test0.40.51.6-0.6-0.70.70.70.70.50.8-0.7-0.30.3-0.0-0.70.3-0.5-0.4-0.40.8-0.9-1.3-1.2-1.2
Locomotion velocity, NPP test0.20.31.5-0.4-0.40.40.40.40.20.5-0.40.0-0.0-0.3-0.3-0.0-0.8-0.7-0.70.5-1.0-1.2-0.9-0.9
Intraocular pressure0.30.62.3-0.00.7-0.7-0.7-0.7-0.4-0.70.70.2-0.3-0.40.8-0.2-0.0-0.0-0.0-1.41.1-0.71.41.5
Delta distance traveled before/after self-admin0.80.81.3-1.1-1.11.01.01.01.10.8-1.1-0.90.90.9-0.80.90.81.11.10.50.7-0.9-0.6-0.4
Delta ambulatory time before/after self-admin0.61.01.8-1.1-1.31.21.21.21.21.1-1.3-0.90.90.8-1.00.90.60.80.80.90.3-1.0-1.0-0.9
Parametrial fat weight0.41.01.5-0.9-1.21.21.21.21.21.0-1.2-0.91.01.0-1.11.00.80.90.91.10.3-0.2-1.0-1.0
Pavlov. Cond. lever latency0.30.41.50.00.3-0.3-0.3-0.30.0-0.40.3-0.20.20.50.30.30.90.80.8-0.61.20.81.01.0
Pavlov. Cond. magazine entry latency1.41.82.41.41.5-1.5-1.5-1.5-1.5-1.31.51.4-1.4-1.51.4-1.5-1.4-1.5-1.5-1.3-1.00.31.11.0
Pavlov. Cond. change in total contacts0.10.10.2-0.2-0.30.40.40.40.30.4-0.3-0.40.40.3-0.50.30.30.10.10.50.10.2-0.4-0.4
Pavlov. Cond. index score0.40.51.20.50.5-0.5-0.5-0.5-0.7-0.40.50.7-0.7-0.90.5-0.8-1.0-1.1-1.1-0.3-1.0-0.4-0.0-0.1
Pavlov. Cond. latency score0.40.61.80.60.4-0.4-0.4-0.4-0.7-0.30.40.8-0.8-1.00.4-0.9-1.2-1.2-1.2-0.1-1.3-0.3-0.2-0.3
Pavlov. Cond. lever contacts0.30.41.2-0.3-0.50.50.50.50.20.6-0.5-0.10.1-0.3-0.5-0.0-0.6-0.6-0.60.7-1.0-1.0-1.1-1.1
Pavlov. Cond. magazine entry number0.60.81.0-0.8-1.00.90.90.91.00.8-1.0-0.80.91.0-0.90.90.91.01.00.90.50.0-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.20.20.80.30.6-0.6-0.6-0.6-0.4-0.50.60.1-0.2-0.10.4-0.20.10.10.1-0.70.60.50.80.9
Pavlov. Cond. lever-magazine prob. diff.0.40.61.30.70.6-0.6-0.6-0.6-0.8-0.50.60.8-0.8-1.00.6-0.9-1.1-1.2-1.2-0.4-1.1-0.20.10.0
Pavlov. Cond. response bias0.50.60.90.60.8-0.8-0.8-0.8-0.8-0.60.80.7-0.8-0.90.7-0.8-0.9-1.0-1.0-0.8-0.5-0.30.50.5
Pavlov. Cond. lever latency1.31.82.9-1.3-1.31.31.31.31.41.5-1.3-1.61.61.7-1.61.51.61.31.31.40.8-0.1-1.2-1.2
Pavlov. Cond. magazine entry latency1.62.33.51.51.4-1.4-1.4-1.4-1.5-1.71.41.8-1.8-1.91.7-1.6-1.8-1.7-1.7-1.5-1.20.21.31.2
Pavlov. Cond. change in total contacts0.51.11.61.21.1-1.1-1.1-1.1-1.1-1.31.11.2-1.2-1.11.2-1.1-0.9-0.8-0.8-1.1-0.50.71.11.0
Pavlov. Cond. index score1.62.43.31.71.6-1.6-1.6-1.6-1.6-1.81.61.8-1.8-1.81.8-1.7-1.6-1.5-1.5-1.5-0.90.61.41.4
Pavlov. Cond. latency score1.52.43.71.61.5-1.5-1.5-1.5-1.6-1.71.51.8-1.8-1.91.8-1.7-1.8-1.6-1.6-1.5-1.10.21.31.3
Pavlov. Cond. lever contacts1.31.92.61.31.4-1.4-1.4-1.4-1.4-1.61.41.5-1.5-1.61.6-1.5-1.4-1.2-1.2-1.5-0.50.21.41.4
Pavlov. Cond. magazine entry number2.02.63.9-1.7-1.51.51.51.51.71.7-1.5-1.91.92.0-1.71.81.81.81.81.41.2-0.5-1.3-1.2
Pavlov. Cond. intertrial magazine entries0.51.12.3-1.0-0.90.90.90.91.10.8-0.9-1.11.21.4-0.91.31.41.51.50.71.20.0-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.1.82.83.81.81.7-1.7-1.7-1.7-1.7-1.91.71.9-1.9-1.91.8-1.8-1.7-1.7-1.7-1.5-1.10.81.41.3
Pavlov. Cond. response bias2.23.04.11.81.8-1.8-1.8-1.8-1.8-2.01.81.9-1.9-2.02.0-1.8-1.6-1.6-1.6-1.9-0.70.61.81.8
Time in closed arm before self-admin0.20.31.1-0.3-0.70.60.60.60.40.6-0.6-0.20.2-0.0-0.60.0-0.2-0.2-0.20.9-0.6-0.4-1.0-1.0
Time in closed arm after self-admin0.40.44.70.4-0.10.10.10.10.2-0.1-0.2-0.20.40.5-0.40.50.80.60.60.70.82.2-0.0-0.2
Time in open arm before self-admin0.30.32.90.80.5-0.5-0.5-0.5-0.4-0.60.50.4-0.30.20.3-0.10.1-0.1-0.10.0-0.51.70.30.1
Time in open arm after self-admin2.12.33.7-1.9-1.61.61.61.61.71.6-1.6-1.71.61.7-1.41.71.31.71.70.81.0-1.6-0.9-0.7
Bone: periosteal estimation0.81.95.3-0.7-1.61.61.61.61.21.5-1.6-0.81.00.8-1.71.00.50.40.42.3-0.80.5-2.1-2.3
Bone: periosteal perimeter0.20.42.30.5-0.30.30.30.3-0.00.2-0.30.4-0.3-0.3-0.4-0.2-0.6-0.7-0.71.0-1.50.8-1.0-1.3
Bone: post-yield work0.40.71.0-0.8-1.01.01.01.01.00.9-1.0-0.80.80.8-0.90.90.70.70.70.80.4-0.3-0.8-0.7
Progressive ratio test 1 active lever presses0.20.41.7-0.1-0.60.50.50.50.60.3-0.7-0.40.50.9-0.50.80.80.70.70.60.31.3-0.3-0.3
Progressive ratio test 1 breakpoint0.20.41.8-0.1-0.60.50.50.50.60.3-0.7-0.40.50.9-0.50.80.90.70.70.50.31.3-0.3-0.3
Progressive ratio test 1 inactive lever presses0.30.95.91.50.9-1.0-1.0-1.0-0.9-1.10.80.9-0.8-0.40.7-0.7-0.3-0.4-0.4-0.2-0.62.40.60.4
Progressive ratio test 2 active lever presses0.20.33.10.90.5-0.6-0.6-0.6-0.5-0.60.30.5-0.5-0.10.4-0.2-0.1-0.2-0.2-0.0-0.51.80.30.1
Progressive ratio test 2 breakpoint0.30.42.61.00.5-0.6-0.6-0.6-0.5-0.70.40.6-0.6-0.20.5-0.3-0.2-0.3-0.3-0.1-0.61.60.40.2
Progressive ratio test 2 inactive lever presses0.10.33.30.6-0.20.10.10.10.1-0.0-0.30.1-0.00.3-0.30.30.20.10.10.8-0.71.8-0.4-0.7
Incentive Sensitization - Responses0.20.50.70.70.9-0.8-0.8-0.8-0.8-0.80.80.7-0.7-0.50.8-0.6-0.5-0.5-0.5-0.7-0.50.40.60.6
Incentive Sensitization - Breakpoint0.30.60.90.80.9-0.8-0.8-0.8-0.9-0.80.90.8-0.8-0.70.8-0.8-0.7-0.7-0.7-0.7-0.70.40.60.5
Sum of active levers in priming session hrs 5-60.20.20.30.30.5-0.5-0.5-0.5-0.5-0.40.60.3-0.4-0.50.4-0.4-0.3-0.3-0.3-0.40.20.10.50.5
Progressive ratio0.41.22.8-0.7-0.90.80.80.81.00.7-0.9-1.11.21.7-1.01.41.51.61.60.90.81.0-0.4-0.5
Food seeking constrained by brief footshock1.31.72.70.61.3-1.2-1.2-1.2-1.3-1.01.31.1-1.3-1.61.4-1.5-1.6-1.5-1.5-1.6-0.5-1.41.11.2
Seeking ratio, punishment vs. effort1.22.65.21.01.5-1.4-1.4-1.4-1.6-1.31.51.6-1.7-2.31.7-2.0-2.0-2.0-2.0-1.8-0.6-1.51.21.4
Retroperitoneal fat weight1.77.612.2-2.8-2.72.62.62.63.12.4-2.6-3.13.13.4-2.53.33.53.53.51.93.3-0.5-1.1-1.0
Reaction time number correct0.31.12.9-1.3-0.80.80.80.81.10.9-0.8-1.31.21.3-0.81.21.41.51.50.31.7-0.7-0.10.1
Reaction time mean minus median0.21.42.21.21.3-1.2-1.2-1.2-1.3-1.11.31.3-1.3-1.51.2-1.4-1.3-1.4-1.4-1.0-0.90.10.80.8
Reaction time mean minus median AUC0.21.43.91.00.8-0.7-0.7-0.7-1.1-0.70.81.4-1.3-1.70.8-1.5-1.9-2.0-2.0-0.4-1.9-0.5-0.2-0.2
Reaction time num false alarms0.50.81.4-0.9-1.01.01.01.01.10.9-1.0-0.90.91.2-0.81.21.01.11.10.70.6-0.2-0.5-0.6
Reaction time num false alarms AUC0.40.81.5-0.9-0.90.90.90.91.10.8-0.9-0.91.01.2-0.71.21.11.21.20.60.9-0.2-0.3-0.3
Reaction time trials correct on left0.31.12.9-1.3-0.80.80.80.81.10.9-0.8-1.31.21.3-0.81.21.41.51.50.31.7-0.7-0.10.1
Reaction time trials on left0.31.12.6-1.3-0.80.80.80.81.10.9-0.8-1.31.21.2-0.81.21.41.41.40.31.6-0.7-0.20.0
Reaction time mean0.51.22.90.90.9-0.8-0.8-0.8-1.2-0.60.91.2-1.2-1.60.8-1.5-1.6-1.7-1.7-0.6-1.4-0.60.10.2
Reaction time mean AUC0.20.61.60.60.5-0.4-0.4-0.4-0.8-0.30.50.8-0.8-1.20.4-1.0-1.2-1.3-1.3-0.2-1.1-0.4-0.2-0.1
Median of all reaction times0.40.71.90.60.6-0.5-0.5-0.5-0.9-0.30.60.8-0.9-1.30.5-1.1-1.3-1.4-1.4-0.3-1.2-0.6-0.2-0.1
Reaction time omissions0.10.10.30.40.00.00.00.0-0.20.00.00.3-0.2-0.4-0.1-0.3-0.4-0.5-0.50.5-0.60.5-0.5-0.6
Reaction time false alarm rate0.20.30.4-0.4-0.70.70.70.70.60.5-0.7-0.30.40.5-0.50.60.30.40.40.5-0.0-0.2-0.5-0.6
Reaction time premature initiation rate1.21.93.31.21.7-1.7-1.7-1.7-1.4-1.71.71.2-1.3-1.11.6-1.1-0.9-0.8-0.8-1.8-0.20.41.71.8
Reaction time premature initiations0.41.13.50.61.3-1.3-1.3-1.3-0.9-1.21.30.5-0.6-0.41.2-0.5-0.20.00.0-1.70.80.21.71.9
Std. dev. reaction times0.30.82.00.90.7-0.6-0.6-0.6-0.9-0.70.71.1-1.1-1.20.8-1.1-1.3-1.4-1.4-0.5-1.2-0.20.20.2
Reaction time trials completed0.31.12.6-1.3-0.80.80.80.81.10.9-0.8-1.31.21.2-0.81.21.41.41.40.31.6-0.7-0.20.0
Reaction time trials AUC0.41.33.3-1.4-0.80.90.90.91.10.9-0.8-1.41.31.4-0.81.31.51.61.60.31.8-0.7-0.10.1
Run reversals in cocaine runway, females1.92.24.21.31.3-1.2-1.2-1.2-1.6-1.21.31.7-1.7-1.71.4-1.8-2.0-2.0-2.0-1.1-2.0-0.40.60.6
Run reversals in cocaine runway, males2.02.24.01.71.4-1.4-1.4-1.4-1.7-1.21.41.7-1.7-2.01.3-1.8-1.9-1.9-1.9-0.8-1.50.70.70.5
Latency to leave start box in cocaine runway0.50.72.0-0.7-1.01.01.01.00.70.8-1.0-0.20.3-0.1-0.80.3-0.6-0.3-0.30.9-0.9-1.4-1.4-1.3
Latency to leave start box in cocaine runway, F1.01.23.7-0.9-1.21.21.21.20.81.2-1.1-0.30.4-0.2-1.00.4-0.8-0.5-0.51.2-1.1-1.9-1.8-1.7
Latency to leave start box in cocaine runway, M0.10.10.20.00.0-0.1-0.1-0.10.1-0.3-0.0-0.00.00.20.20.10.30.30.3-0.20.40.40.30.4
Std. dev. time between licks in bursts0.50.92.31.20.8-0.8-0.8-0.8-1.0-0.70.81.1-1.0-1.10.6-1.1-1.2-1.1-1.1-0.1-1.50.8-0.2-0.2
Total sessions with >9 infusions0.70.913.21.1-0.1-0.0-0.0-0.00.0-0.2-0.30.10.10.6-0.40.50.80.70.71.2-0.23.6-0.4-0.7
Short access day 1 total inactive lever presses0.40.81.71.11.2-1.1-1.1-1.1-1.0-1.21.00.8-0.8-0.51.0-0.8-0.3-0.1-0.1-0.9-0.11.31.11.0
Short access day 10 total inactive lever presses0.21.12.60.91.2-1.3-1.3-1.3-0.8-1.21.00.4-0.50.11.1-0.40.50.30.3-1.20.91.61.61.6
Short access day 1 total infusions0.51.014.41.20.2-0.2-0.2-0.2-0.1-0.3-0.10.10.10.6-0.40.60.80.70.71.2-0.23.8-0.3-0.7
Short access day 10 total infusions0.20.34.20.5-0.10.00.00.00.1-0.1-0.3-0.00.10.6-0.20.50.60.50.50.5-0.02.0-0.1-0.2
Short access total infusions0.71.011.00.7-0.30.20.20.20.30.2-0.6-0.20.41.0-0.70.90.90.90.91.5-0.23.3-0.6-1.0
Short access day 1 locomotion1.01.710.72.01.3-1.3-1.3-1.3-1.2-1.61.11.3-1.1-0.51.2-0.7-0.2-0.4-0.4-0.6-0.63.31.10.9
Short access day 10 total locomotion1.35.315.02.92.7-2.8-2.8-2.8-2.3-2.82.62.0-2.0-1.02.4-1.5-0.7-0.8-0.8-2.0-0.53.92.52.4
Short access total locomotion1.01.69.91.91.3-1.4-1.4-1.4-1.2-1.51.11.1-1.0-0.41.1-0.6-0.1-0.2-0.2-0.7-0.43.11.11.0
One hour access (0.3 mA shock)0.10.11.00.1-0.0-0.0-0.0-0.00.2-0.0-0.3-0.20.30.5-0.10.50.50.50.50.20.41.00.20.0
Compulsive drug intake0.00.00.3-0.1-0.10.10.10.10.10.0-0.10.1-0.1-0.30.0-0.2-0.3-0.1-0.10.0-0.2-0.5-0.0-0.1
One hour access (shock baseline)0.20.43.30.90.7-0.7-0.7-0.7-0.6-0.70.50.5-0.40.10.5-0.00.1-0.1-0.1-0.2-0.21.80.50.4
Social response proportion0.50.71.60.40.7-0.7-0.7-0.7-0.9-0.50.70.8-0.8-1.00.7-1.1-1.3-0.9-0.9-0.8-1.1-1.20.20.3
Social responses7.09.214.12.93.0-3.0-3.0-3.0-3.3-3.03.03.5-3.5-3.63.1-3.6-3.8-3.4-3.4-2.7-3.1-0.31.91.8
Social time1.01.52.4-1.5-1.11.11.11.11.31.3-1.1-1.61.51.4-1.31.31.41.41.40.81.3-0.9-0.7-0.5
Soleus weight5.917.320.9-4.5-4.54.54.54.54.64.6-4.5-4.54.64.4-4.44.44.24.24.23.73.2-2.0-3.4-3.1
Bone: stiffness3.46.18.5-2.3-2.92.92.92.92.72.8-2.9-2.42.52.4-2.82.41.92.02.02.90.7-0.5-2.7-2.7
Tibialis anterior weight1.34.65.7-2.4-2.32.32.32.32.42.4-2.3-2.42.42.2-2.32.22.22.02.01.91.8-1.1-1.7-1.6
Time to tail flick, vehicle, before self-admin1.01.32.51.41.1-1.1-1.1-1.1-1.3-1.01.01.2-1.2-1.60.9-1.4-1.4-1.4-1.4-0.3-0.71.00.40.2
Time to tail flick, vehicle, after self-admin0.30.62.10.30.9-0.7-0.7-0.7-0.6-0.91.00.4-0.5-0.21.0-0.5-0.3-0.2-0.2-1.40.5-0.11.31.4
Time to tail flick, test, before self-admin0.60.72.80.90.5-0.4-0.4-0.4-0.7-0.50.41.0-0.9-0.90.4-0.8-1.1-1.3-1.30.1-1.70.6-0.3-0.4
Time to tail flick, test, after self-admin0.00.10.20.2-0.10.10.10.1-0.0-0.0-0.10.2-0.1-0.1-0.1-0.1-0.2-0.1-0.10.4-0.40.4-0.4-0.5
Delta time to tail flick, vehicle, before/after SA1.41.53.1-1.8-0.91.11.11.11.31.0-0.8-1.41.31.6-0.71.31.31.51.5-0.11.6-1.70.00.3
Delta time to tail flick, test, before/after SA0.20.31.8-0.30.2-0.3-0.3-0.30.1-0.20.3-0.30.20.20.20.10.50.70.7-0.71.3-0.50.80.9
Tibia length0.72.03.21.21.5-1.5-1.5-1.5-1.4-1.51.51.4-1.5-1.51.7-1.4-1.4-1.4-1.4-1.8-0.7-0.01.51.5
Ambulatory time before self-admin0.20.60.90.80.9-0.9-0.9-0.9-0.9-0.70.90.7-0.8-0.80.8-0.7-0.7-0.7-0.7-0.6-0.30.30.70.6
Ambulatory time after self-admin0.00.10.6-0.3-0.30.20.20.20.20.2-0.2-0.10.1-0.1-0.10.1-0.10.20.20.00.2-0.8-0.2-0.1
Bone: tissue strength4.74.96.5-2.0-2.42.42.42.42.32.4-2.4-2.32.32.3-2.52.32.02.12.12.61.0-0.1-2.2-2.2
Total heroin consumption1.72.03.51.31.4-1.3-1.3-1.3-1.5-1.31.51.6-1.6-1.81.5-1.7-1.9-1.7-1.7-1.2-1.4-0.30.80.8
Bone: trabecular number0.30.62.70.4-0.20.20.20.2-0.2-0.2-0.20.9-0.8-1.00.3-0.7-1.4-1.2-1.20.2-1.6-0.6-0.5-0.7
Bone: trabecular spacing0.60.94.20.00.7-0.7-0.7-0.7-0.1-0.50.7-0.50.40.80.30.41.41.11.1-1.02.11.21.51.6
Bone: trabecular thickness1.52.08.1-0.3-1.41.41.41.40.71.2-1.40.00.2-0.3-1.30.1-1.0-0.9-0.92.2-2.5-0.8-2.6-2.8
Bone: trabecular tissue density3.25.78.7-2.3-2.42.42.42.42.62.3-2.4-2.72.72.8-2.42.82.82.92.92.02.3-0.1-1.5-1.3
Water consumed over 24 hours0.61.11.9-0.9-1.21.21.21.21.11.1-1.2-0.80.90.9-1.11.00.60.60.61.3-0.2-0.3-1.4-1.4
Number of responses in last shaping day3.54.512.62.92.4-2.6-2.6-2.6-2.3-2.62.32.1-2.0-1.32.2-1.6-0.9-1.1-1.1-1.6-0.83.52.01.8