Hub : Genes

Bloc1s1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Bloc1s1 0.09 0.05 3.8e-11 0.07 0.07 0.07 0.07 2.9e-11 8.9e-11 5.3e-11 4.0e-11
2 LHb mRNA stability Bloc1s1 0.44 0.18 1.1e-07 0.28 0.27 0.29 0.28 1.9e-07 3.7e-07 1.2e-07 1.9e-07
3 OFC gene expression Bloc1s1 0.25 0.14 7.2e-04 0.14 0.12 0.13 0.14 3.2e-04 7.9e-04 5.4e-04 4.0e-04
4 PL gene expression Bloc1s1 0.07 0.05 1.1e-05 0.05 0.04 0.04 0.04 4.9e-06 1.5e-05 2.3e-05 9.6e-06
5 Eye intron excision ratio chr7_1932787_1934691 0.29 0.18 8.8e-03 0.14 0.1 0.1 0.12 3.5e-03 1.1e-02 1.2e-02 5.8e-03
6 Brain mRNA stability Bloc1s1 0.34 0.16 0.0e+00 0.21 0.2 0.21 0.21 4.3e-19 9.7e-19 5.4e-19 2.4e-19
7 IL gene expression Bloc1s1 0.22 0.14 5.0e-03 0.07 0.02 0.03 0.04 1.0e-02 1.1e-01 6.7e-02 3.4e-02
8 PL mRNA stability Bloc1s1 0.24 0.13 0.0e+00 0.18 0.17 0.17 0.18 1.2e-19 1.3e-18 9.4e-19 2.8e-19
9 OFC mRNA stability Bloc1s1 0.2 0.12 1.9e-03 0.1 0.09 0.11 0.09 2.8e-03 3.4e-03 1.3e-03 3.1e-03
10 pVTA mRNA stability Bloc1s1 0.08 0.05 2.3e-05 0.04 0.05 0.03 0.05 6.1e-04 4.1e-05 1.3e-03 1.3e-04
11 Liver gene expression Bloc1s1 0.08 0.06 3.5e-06 0.03 0.04 0.06 0.04 2.1e-04 2.8e-05 3.2e-07 2.2e-05
12 IL mRNA stability Bloc1s1 0.49 0.18 3.9e-07 0.17 0.17 0.18 0.18 5.5e-05 6.1e-05 3.7e-05 4.9e-05
13 Brain gene expression Bloc1s1 0.1 0.06 4.8e-07 0.05 0.06 0.07 0.06 1.8e-05 1.8e-06 8.9e-07 3.0e-06
14 BLA gene expression Bloc1s1 0.14 0.08 1.7e-07 0.14 0.11 0.11 0.12 1.2e-07 1.9e-06 1.7e-06 1.1e-06
15 pVTA isoform ratio XM_063263093.1 0.03 0.02 8.4e-03 0.03 0.02 0.03 0.03 1.6e-03 6.9e-03 3.4e-03 3.9e-03
16 pVTA intron excision ratio chr7_1934763_1935447 0.04 0.03 6.9e-04 0.01 0.01 0.01 0.02 2.5e-02 2.8e-02 2.9e-02 1.5e-02
17 LHb gene expression Bloc1s1 0.16 0.11 8.4e-03 0.09 0.09 0.09 0.09 3.3e-03 4.1e-03 3.1e-03 4.8e-03
18 Adipose gene expression Bloc1s1 0.05 0.04 1.5e-05 0.01 0.02 0.03 0.03 1.6e-02 1.1e-03 1.2e-04 5.6e-04
19 BLA mRNA stability Bloc1s1 0.49 0.3 5.5e-08 0.13 0.13 0.15 0.14 2.5e-07 2.6e-07 2.6e-08 9.1e-08
20 NAcc gene expression Bloc1s1 0.04 0.02 1.0e-04 0.02 0.02 0.02 0.02 9.2e-04 3.0e-04 1.1e-03 1.6e-03
21 Adipose mRNA stability Bloc1s1 0.07 0.05 8.3e-06 0.02 0.05 0.05 0.05 1.1e-03 5.9e-06 3.5e-06 5.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.71.24.21.20.3-1.2-1.2-1.20.7-0.91.2-0.10.10.20.9-0.20.70.6-0.6-1.61.80.5-1.82.1
Area under the delay curve0.30.32.80.70.8-0.5-0.5-0.50.6-0.60.70.50.4-0.20.4-0.30.10.1-0.1-0.1-0.21.7-0.50.3
BMI with tail7.827.033.55.65.6-5.5-5.5-5.55.8-5.55.65.75.7-5.65.5-5.6-5.3-5.35.3-4.6-4.02.4-4.13.7
BMI without tail2.26.68.82.92.8-2.8-2.8-2.83.0-2.62.92.82.8-2.72.6-2.8-2.6-2.72.7-2.2-2.01.2-1.91.7
Body weight1.35.68.02.52.8-2.5-2.5-2.52.8-2.42.52.72.6-2.52.3-2.6-2.4-2.62.6-1.5-2.31.8-1.41.1
Weight adjusted by age0.00.10.2-0.2-0.20.30.30.3-0.20.3-0.3-0.2-0.20.0-0.3-0.00.10.2-0.20.40.10.00.4-0.4
Bone surface1.01.810.40.7-0.7-0.7-0.7-0.7-0.0-0.40.7-1.0-0.71.00.50.61.61.5-1.5-1.83.2-0.5-2.12.5
Bone volume1.11.99.01.1-0.3-1.1-1.1-1.10.4-0.81.1-0.6-0.30.70.90.21.31.3-1.3-2.13.0-0.1-2.42.8
Breakpoint value in progressive ratio session1.31.52.3-1.5-1.41.51.51.5-1.41.3-1.5-1.2-1.21.2-1.21.21.01.0-1.01.00.3-1.11.1-1.0
Number of licking bursts2.13.44.81.92.2-1.9-1.9-1.92.1-1.81.92.22.1-2.11.7-2.1-2.1-2.02.0-1.1-2.11.3-0.90.6
Context. condit. distance diff. score0.20.20.40.40.5-0.4-0.4-0.40.5-0.60.40.60.6-0.50.6-0.5-0.6-0.50.5-0.4-0.40.1-0.40.4
Locomotion velocity, session 10.70.73.00.90.8-0.9-0.9-0.90.6-1.00.90.40.5-0.10.8-0.20.30.2-0.2-1.00.91.7-1.51.4
Locomotion distance, session 10.40.42.60.1-0.3-0.1-0.1-0.1-0.3-0.20.1-0.5-0.40.60.10.61.00.9-0.9-0.61.60.6-1.01.1
Locomotion velocity, session 21.31.55.5-0.8-1.40.80.80.8-1.20.8-0.8-1.4-1.31.4-0.71.41.71.8-1.8-0.02.3-0.3-0.40.6
Locomotion distance, session 21.92.66.7-1.1-1.31.11.11.1-1.51.1-1.1-1.8-1.82.1-1.31.92.52.5-2.50.82.61.00.00.0
Locomotion velocity, session 34.45.16.2-2.5-2.22.42.42.4-2.52.3-2.5-2.4-2.42.4-2.42.52.42.3-2.32.31.6-0.31.8-1.8
Locomotion distance, session 30.10.10.2-0.4-0.20.30.30.3-0.30.3-0.4-0.3-0.30.2-0.40.30.20.2-0.20.50.10.10.4-0.4
Stereotopy head waving bouts, day 35.46.38.5-2.6-2.82.52.52.5-2.72.7-2.6-2.9-2.92.8-2.62.82.82.7-2.72.02.3-1.11.7-1.5
Stereotopy head waving duration, day 34.35.17.8-2.3-2.82.32.32.3-2.52.5-2.3-2.6-2.52.3-2.32.42.22.3-2.31.62.1-2.01.6-1.3
Locomotion velocity, session 70.10.10.4-0.3-0.30.20.20.2-0.40.0-0.3-0.2-0.20.2-0.10.40.40.5-0.5-0.10.7-0.2-0.20.3
Locomotion distance, session 70.10.10.60.00.2-0.0-0.0-0.00.2-0.10.00.40.3-0.40.1-0.3-0.6-0.50.50.2-0.8-0.10.4-0.4
Stereotopy head waving bouts, day 70.70.82.2-0.5-0.60.50.50.5-0.80.5-0.5-1.0-0.91.2-0.61.11.41.3-1.30.21.50.7-0.30.3
Stereotopy head waving duration, day 70.60.72.8-0.3-0.50.30.30.3-0.70.3-0.3-0.9-0.81.2-0.41.01.51.3-1.30.01.70.9-0.60.6
Locomotion velocity, session 80.91.14.3-0.3-0.60.40.40.4-0.70.4-0.3-1.1-1.01.4-0.51.11.81.7-1.70.12.11.3-0.60.6
Locomotion distance, session 80.20.40.9-0.4-0.30.40.40.4-0.50.3-0.4-0.6-0.60.8-0.40.61.00.9-0.90.40.90.70.0-0.0
Degree of sensitization distance0.60.60.90.90.8-0.9-0.9-0.90.9-0.90.90.90.9-0.80.9-0.8-0.8-0.70.7-0.8-0.50.3-0.70.6
Degree of sensitization stereotypy0.30.41.50.60.7-0.6-0.6-0.60.4-0.80.60.40.4-0.10.6-0.20.20.1-0.1-0.70.41.2-1.01.0
Conditioned locomotion0.81.03.30.61.2-0.6-0.6-0.60.9-0.70.61.21.1-1.20.6-1.0-1.3-1.51.50.1-1.80.80.2-0.4
Cocaine response after cond. corrected1.61.94.01.21.5-1.2-1.2-1.21.5-1.21.21.71.6-1.81.2-1.7-1.9-1.71.7-0.6-2.00.4-0.30.1
Cocaine response after cond. not corrected1.72.04.51.11.4-1.1-1.1-1.11.4-1.11.11.71.6-1.91.1-1.7-2.1-1.91.9-0.6-2.1-0.0-0.10.0
Cocaine response before conditioning0.50.60.9-0.8-1.00.80.80.8-0.90.9-0.8-1.0-0.90.8-0.80.80.70.6-0.60.40.7-0.90.5-0.3
Saline control response0.60.81.60.91.1-0.9-0.9-0.91.0-0.70.90.90.9-1.00.6-1.0-1.0-1.21.2-0.2-1.30.8-0.10.0
Bone: connectivity density0.30.52.10.80.0-0.8-0.8-0.80.4-0.40.8-0.2-0.00.10.5-0.10.50.5-0.5-1.11.50.0-1.21.4
Bone: cortical apparent density1.01.31.81.20.9-1.2-1.2-1.21.2-1.31.21.21.2-1.21.3-1.2-1.2-1.01.0-1.3-0.8-0.4-1.01.0
Bone: cortical area1.01.54.51.40.6-1.4-1.4-1.41.0-1.31.40.70.8-0.71.5-0.8-0.3-0.30.3-2.00.8-0.4-1.92.1
Bone: cortical porosity0.10.10.60.0-0.3-0.0-0.0-0.0-0.1-0.10.0-0.1-0.1-0.00.2-0.00.10.2-0.2-0.60.7-0.8-0.50.7
Bone: cortical porosity0.30.31.50.4-0.2-0.4-0.4-0.40.2-0.40.40.00.2-0.30.6-0.30.00.1-0.1-1.11.0-1.0-1.01.2
Bone: cortical thickness1.42.34.91.71.0-1.7-1.7-1.71.5-1.71.71.31.4-1.41.9-1.4-1.1-1.11.1-2.2-0.2-0.5-1.92.0
Bone: cortical thickness0.60.81.60.80.9-0.8-0.8-0.80.9-0.90.81.11.0-1.00.8-0.9-1.1-1.11.1-0.6-1.30.2-0.30.2
Bone: cortical tissue density0.70.91.31.00.8-1.0-1.0-1.01.0-1.11.01.01.0-1.01.1-1.0-1.0-0.80.8-1.1-0.7-0.4-0.90.9
Condit. Reinf. active minus inactive responses2.12.33.2-1.6-1.71.61.61.6-1.71.5-1.6-1.6-1.71.5-1.51.61.51.8-1.81.21.4-1.01.1-0.9
Condit. Reinf. active-inactive response ratio0.60.61.8-0.9-0.90.90.90.9-0.80.9-0.9-0.7-0.70.3-0.80.50.20.5-0.50.70.2-1.30.9-0.8
Condit. Reinf. active responses2.73.36.0-1.8-2.01.71.71.7-2.01.7-1.8-2.0-2.02.0-1.62.02.22.4-2.41.12.2-0.80.8-0.6
Condit. Reinf. inactive responses1.21.43.6-0.9-1.10.80.80.8-1.20.8-0.9-1.3-1.31.6-0.91.41.91.8-1.80.51.90.30.00.1
Incentive salience index mean1.11.43.0-1.1-1.21.01.01.0-1.30.9-1.1-1.3-1.31.4-1.01.31.61.7-1.70.61.7-0.20.3-0.2
Condit. Reinf. lever presses0.50.62.80.10.0-0.1-0.1-0.1-0.3-0.30.1-0.4-0.40.80.10.61.31.2-1.2-0.41.71.5-1.01.0
Condit. Reinf. active minus inactive responses2.73.64.9-2.2-2.02.22.22.2-2.02.2-2.2-1.9-1.91.6-2.21.81.21.3-1.32.10.5-1.42.2-2.1
Condit. Reinf. active-inactive response ratio1.21.43.9-1.4-0.81.41.41.4-1.11.3-1.4-0.7-0.80.6-1.40.80.10.2-0.21.7-0.7-0.61.9-2.0
Condit. Reinf. active responses2.02.84.0-1.8-2.01.81.81.8-1.82.0-1.8-1.9-1.81.5-1.81.71.41.4-1.41.41.2-1.51.5-1.3
Condit. Reinf. inactive responses0.40.51.5-0.5-1.00.50.50.5-0.70.7-0.5-1.0-0.90.8-0.60.70.90.8-0.80.11.2-0.70.10.0
Condit. Reinf. lever presses2.83.95.4-2.1-2.12.12.12.1-2.02.3-2.1-2.1-2.12.0-2.32.01.61.5-1.52.10.7-1.22.1-2.1
Condit. Reinf. lever reinforcers received1.62.23.3-1.7-1.71.71.71.7-1.61.8-1.7-1.6-1.61.3-1.71.41.11.0-1.01.40.8-1.41.5-1.4
Conditioned reinforcement - actives0.30.67.9-0.4-1.10.50.50.5-0.40.7-0.2-0.5-0.4-0.3-0.3-0.1-0.2-0.20.2-0.20.5-2.80.3-0.1
Conditioned reinforcement - inactives0.50.79.3-0.2-0.80.30.30.30.00.5-0.00.10.2-0.9-0.0-0.7-1.1-0.80.8-0.3-0.5-3.10.5-0.2
Conditioned locomotion3.74.817.1-2.1-3.32.32.32.3-2.32.5-2.0-2.5-2.31.6-1.91.91.51.8-1.80.82.2-4.11.3-0.8
Patch foraging indifference point 0 sec2.95.37.52.52.0-2.5-2.5-2.52.4-2.42.52.32.4-2.52.6-2.5-2.2-2.42.4-2.7-1.1-0.2-2.22.3
Patch foraging indifference point AUC0.60.91.3-1.0-0.81.01.01.0-1.01.0-1.0-0.8-1.01.0-1.01.00.91.0-1.01.10.5-0.10.9-1.0
Delay disc. indifference point, 0s delay3.13.36.12.32.0-2.2-2.2-2.21.9-2.22.31.51.5-1.12.0-1.3-0.4-0.60.6-1.90.32.5-2.52.3
Delay disc. indifference point, 16s delay0.10.10.5-0.3-0.10.30.30.3-0.40.1-0.3-0.3-0.30.4-0.20.50.40.6-0.60.30.30.70.0-0.1
Delay disc. indifference point, 2s delay0.80.92.61.21.2-1.1-1.1-1.11.0-1.21.20.80.8-0.31.0-0.6-0.0-0.10.1-0.9-0.11.6-1.11.1
Delay disc. indifference point, 24s delay0.60.72.80.91.2-0.8-0.8-0.80.9-1.01.00.90.8-0.60.7-0.7-0.5-0.50.5-0.4-0.51.7-0.70.5
Delay disc. indifference point, 4s delay0.30.31.00.1-0.1-0.1-0.1-0.1-0.1-0.00.1-0.4-0.40.7-0.10.50.90.8-0.8-0.11.01.0-0.50.4
Delay disc. indifference point, 8s delay0.30.31.30.60.8-0.4-0.4-0.40.7-0.40.60.60.6-0.50.3-0.6-0.3-0.40.40.2-0.81.20.0-0.3
Indifference point function ln k0.10.11.0-0.0-0.20.00.00.00.00.0-0.00.10.2-0.30.2-0.1-0.3-0.50.5-0.4-0.2-1.0-0.00.2
Indifference point function log k0.10.11.0-0.0-0.20.00.00.00.00.0-0.00.10.2-0.30.2-0.1-0.3-0.50.5-0.4-0.2-1.0-0.00.2
Patch foraging total patch changes 0 sec2.54.66.62.31.8-2.3-2.3-2.32.3-2.22.32.22.3-2.32.5-2.3-2.1-2.32.3-2.6-1.1-0.3-2.02.2
Patch foraging total patch changes 12 sec1.62.13.21.51.5-1.5-1.5-1.51.7-1.41.51.61.6-1.71.4-1.8-1.7-1.71.7-1.1-1.40.1-0.80.7
Patch foraging total patch changes 18 sec0.10.10.20.30.4-0.3-0.3-0.30.3-0.40.30.30.3-0.10.3-0.3-0.1-0.10.1-0.2-0.00.5-0.40.3
Patch foraging total patch changes 24 sec0.50.81.21.01.0-1.1-1.1-1.11.0-1.11.00.80.9-0.61.0-0.8-0.6-0.60.6-1.0-0.40.8-1.01.0
Patch foraging total patch changes 6 sec1.62.43.41.71.2-1.7-1.7-1.71.6-1.61.71.51.6-1.81.7-1.7-1.6-1.51.5-1.8-0.6-0.4-1.51.6
Patch foraging time to switch 0 sec0.40.81.51.20.9-1.2-1.2-1.21.0-1.01.20.50.6-0.60.8-0.8-0.3-0.30.3-1.00.40.9-1.21.2
Patch foraging water rate 0 sec0.30.62.10.40.6-0.4-0.4-0.40.6-0.40.40.90.8-1.00.5-0.8-1.2-1.21.2-0.2-1.5-0.40.2-0.2
Patch foraging water rate 12 sec0.40.82.70.40.6-0.4-0.4-0.40.7-0.50.41.01.0-1.20.6-0.9-1.4-1.41.4-0.4-1.6-0.70.1-0.1
Patch foraging water rate 18 sec0.71.04.2-0.9-0.30.90.90.9-0.40.8-0.90.10.0-0.3-0.8-0.1-0.9-0.80.81.2-2.1-1.01.8-1.9
Patch foraging water rate 24 sec1.41.99.90.41.2-0.4-0.4-0.41.1-0.50.41.61.4-1.70.5-1.5-2.2-2.22.20.3-3.1-0.31.0-1.2
Patch foraging water rate 6 sec1.21.84.0-1.6-1.31.61.61.6-1.31.6-1.6-0.8-0.90.5-1.30.8-0.1-0.00.01.4-1.0-2.02.0-1.9
Seeking ratio, delayed vs. immediate footshock1.51.83.4-1.2-1.81.31.31.3-1.51.4-1.1-1.6-1.51.7-1.21.51.41.4-1.40.61.1-1.60.7-0.5
Distance traveled before self-admin1.31.72.2-1.5-1.31.41.41.4-1.51.3-1.4-1.3-1.41.5-1.31.41.41.4-1.41.10.8-0.31.0-0.9
Distance traveled after self-admin0.10.11.00.20.3-0.2-0.2-0.20.2-0.10.20.10.00.1-0.0-0.00.2-0.20.20.2-0.11.0-0.0-0.1
Extensor digitorum longus weight4.718.424.84.44.6-4.4-4.4-4.44.8-4.24.44.84.8-4.94.2-4.9-5.0-4.94.9-3.3-4.31.4-2.52.2
Bone: elastic displacement0.00.00.1-0.1-0.10.10.10.1-0.10.0-0.10.00.0-0.00.1-0.0-0.1-0.10.1-0.20.0-0.3-0.10.1
Bone: elastic work1.01.31.91.31.1-1.3-1.3-1.31.2-1.31.31.01.1-0.91.3-1.0-0.7-0.80.8-1.4-0.20.6-1.31.4
Bone: endosteal estimation0.40.92.21.10.6-1.1-1.1-1.10.9-1.11.10.70.8-0.81.2-0.9-0.6-0.60.6-1.50.2-0.5-1.31.4
Bone: endosteal perimeter0.30.72.8-0.5-1.00.50.50.5-0.80.6-0.5-1.1-1.01.0-0.50.91.21.2-1.2-0.11.7-0.8-0.20.4
Epididymis fat weight0.10.41.6-0.6-0.20.70.70.7-0.30.6-0.6-0.2-0.30.2-0.70.2-0.1-0.10.11.1-0.8-0.11.1-1.3
Delta time in closed arm before/after self-admin1.31.25.80.20.4-0.2-0.2-0.20.7-0.10.21.01.0-1.30.3-1.2-2.0-1.71.70.1-2.4-1.50.8-0.9
Delta time in open arm before/after self-admin1.61.64.71.41.8-1.4-1.4-1.41.4-1.51.41.41.3-0.91.1-1.1-0.7-1.11.1-0.6-0.92.2-0.90.7
Diff in mean of infusions in LGA sessions2.22.63.6-1.8-1.81.81.81.8-1.81.8-1.9-1.7-1.71.5-1.81.71.31.4-1.41.51.0-1.11.5-1.3
Delay discount exponential model param0.20.32.7-0.5-0.70.40.40.4-0.40.5-0.6-0.4-0.30.0-0.30.2-0.2-0.20.20.00.2-1.60.4-0.2
Extinction: sum of active levers before priming1.92.03.1-1.7-1.41.71.71.7-1.61.6-1.7-1.3-1.41.1-1.71.30.81.0-1.01.80.2-0.81.7-1.7
Active lever presses in extinction session 60.20.20.5-0.4-0.50.40.40.4-0.50.3-0.4-0.5-0.50.4-0.30.40.60.7-0.70.10.7-0.10.10.0
Bone: final force3.14.98.32.71.9-2.7-2.7-2.72.3-2.62.71.92.0-1.82.6-1.9-1.3-1.41.4-2.9-0.10.6-2.82.9
Bone: final moment3.04.98.22.71.9-2.7-2.7-2.72.3-2.62.71.92.0-1.82.5-1.9-1.3-1.41.4-2.9-0.10.6-2.72.8
Food consumed during 24 hour testing period0.40.50.70.80.8-0.8-0.8-0.80.8-0.80.80.80.8-0.70.7-0.7-0.7-0.60.6-0.6-0.60.3-0.60.5
Glucose1.72.74.11.82.0-1.8-1.8-1.81.8-1.81.81.81.8-1.51.6-1.7-1.4-1.61.6-1.2-1.41.6-1.21.0
Heart weight0.40.61.2-0.9-0.81.01.01.0-0.80.9-0.9-0.6-0.70.5-0.80.50.20.3-0.31.0-0.1-0.81.0-1.1
Delay discount hyperbolic model param0.50.63.2-0.9-1.00.80.80.8-0.80.9-0.9-0.7-0.60.3-0.70.5-0.00.0-0.00.40.2-1.80.8-0.6
Intermittent access intake day 1-15 change1.02.18.1-1.6-1.91.81.81.8-1.41.8-1.7-1.2-1.20.7-1.40.80.30.3-0.31.0-0.1-2.81.5-1.4
Intermittent access intake escalation0.91.87.1-1.5-1.81.71.71.7-1.31.7-1.6-1.2-1.10.6-1.40.70.20.2-0.21.0-0.2-2.71.5-1.4
Intermittent access intake escalation 21.31.52.7-1.4-1.51.51.51.5-1.21.5-1.5-1.1-1.10.9-1.30.80.70.5-0.51.00.0-1.61.3-1.1
Intermitt. access day 1 inactive lever presses0.31.33.3-1.4-1.01.41.41.4-1.01.5-1.3-0.7-0.80.2-1.40.6-0.10.0-0.01.6-0.5-1.21.8-1.8
Intermitt. access day 15 inactive lever presses0.61.21.9-1.3-1.11.41.41.4-1.21.3-1.3-1.1-1.10.9-1.31.00.81.0-1.01.20.4-0.31.1-1.1
Intermitt. access escalation Index0.20.30.90.60.1-0.6-0.6-0.60.3-0.50.50.10.20.00.6-0.10.30.2-0.2-0.80.60.0-0.90.9
Intermittent access day 1 total infusions0.10.21.70.2-0.1-0.2-0.2-0.20.2-0.10.50.20.3-0.60.2-0.4-0.7-0.50.5-0.3-0.2-1.3-0.10.0
Intermittent access day 15 total infusions0.40.67.4-0.5-1.20.60.60.6-0.50.7-0.3-0.5-0.4-0.0-0.30.1-0.2-0.00.0-0.20.2-2.70.3-0.1
Intermittent access terminal intake (last 3 days)0.40.55.4-0.5-1.20.60.60.6-0.60.6-0.3-0.7-0.60.2-0.30.30.30.3-0.3-0.40.8-2.30.00.2
Intermittent access total infusions0.30.34.7-0.0-0.70.10.10.1-0.10.20.2-0.1-0.0-0.40.1-0.3-0.4-0.20.2-0.60.3-2.2-0.10.3
Intermittent access day 1 locomotion0.10.21.0-0.2-0.20.30.30.3-0.10.3-0.10.10.1-0.5-0.2-0.2-0.7-0.60.60.3-0.4-1.00.5-0.6
Intermittent access day 15 total locomotion0.91.711.7-1.4-1.91.51.51.5-1.21.6-1.2-1.0-0.90.3-1.10.60.00.1-0.10.60.2-3.41.3-1.0
Intermittent access total locomotion0.40.53.3-0.7-1.00.80.80.8-0.60.9-0.5-0.6-0.60.2-0.70.30.00.1-0.10.40.2-1.80.8-0.6
Intermittent access standard deviation1.12.311.0-1.5-2.31.71.71.7-1.61.6-1.4-1.6-1.51.0-1.21.20.91.1-1.10.41.4-3.30.8-0.4
Left kidney weight0.00.10.60.20.4-0.1-0.1-0.10.2-0.10.10.30.2-0.10.0-0.0-0.1-0.20.20.3-0.40.70.1-0.3
Right kidney weight0.10.51.5-0.7-0.30.70.70.7-0.60.7-0.8-0.5-0.60.6-0.90.80.50.6-0.61.2-0.00.70.9-1.1
Cocaine induced anxiety1.01.53.3-0.9-1.30.90.90.9-1.20.9-0.9-1.5-1.41.8-1.01.51.81.8-1.80.41.6-0.20.10.0
Post-drug Anxiety0.80.82.5-0.2-0.90.30.30.3-0.60.3-0.2-1.0-0.91.6-0.31.01.51.6-1.6-0.51.3-0.2-0.60.8
Baseline Anxiety0.00.00.10.20.0-0.1-0.1-0.10.2-0.10.20.10.1-0.00.1-0.1-0.1-0.10.1-0.2-0.3-0.1-0.10.1
Tail length3.212.616.2-3.8-3.63.83.83.8-3.83.9-3.8-3.9-3.93.7-4.03.83.53.3-3.33.72.3-1.33.3-3.2
Length with tail1.46.18.5-2.8-2.42.82.82.8-2.62.8-2.8-2.6-2.62.4-2.92.42.02.0-2.02.91.0-1.12.7-2.6
Length without tail0.20.61.30.70.9-0.6-0.6-0.60.8-0.70.61.00.9-1.00.7-0.9-1.1-1.11.1-0.4-1.10.3-0.20.1
Times rat made contact with spout1.11.22.21.01.3-1.0-1.0-1.01.2-1.11.01.31.3-1.51.0-1.4-1.4-1.41.4-0.6-1.10.4-0.50.3
Lifetime Intake0.60.77.90.3-0.5-0.2-0.2-0.20.3-0.20.70.20.4-0.90.6-0.8-0.8-0.70.7-1.20.2-2.8-0.60.8
Liver weight, left0.40.71.10.91.0-0.9-0.9-0.90.9-1.00.91.01.0-0.90.9-0.9-0.9-0.90.9-0.6-0.80.7-0.60.4
Liver weight, right0.10.21.3-0.10.20.20.20.2-0.00.2-0.2-0.1-0.20.2-0.40.10.20.1-0.10.8-0.31.10.5-0.7
Locomotor activity2.43.86.1-1.9-1.91.91.91.9-2.21.8-1.9-2.3-2.22.4-1.92.32.52.2-2.21.42.30.21.0-0.8
Locomotor testing distance1.12.03.1-1.3-1.61.41.41.4-1.61.3-1.3-1.7-1.61.7-1.31.71.71.7-1.70.91.7-0.30.6-0.5
Locomotor testing rearing0.00.00.2-0.20.10.20.20.2-0.00.2-0.2-0.0-0.0-0.0-0.2-0.0-0.1-0.30.30.3-0.20.40.3-0.4
Locomotion in novel chamber0.10.11.70.1-0.30.00.00.00.00.00.10.00.1-0.30.2-0.2-0.4-0.20.2-0.4-0.0-1.3-0.10.2
Locomotion in novel chamber post-restriction3.25.37.9-2.5-2.32.52.52.5-2.52.2-2.4-2.4-2.52.8-2.42.62.52.5-2.52.21.2-0.51.9-1.8
Fecal boli incidents, locomotor time 10.71.02.20.81.3-0.8-0.8-0.81.0-0.90.81.21.1-1.10.7-1.0-1.2-1.21.2-0.3-1.51.1-0.20.0
Change in fecal boli incidents, locomotor task0.60.62.4-0.4-0.80.40.40.4-0.70.4-0.4-0.9-0.80.9-0.40.91.21.1-1.1-0.11.50.0-0.40.5
Time >=10cm from walls, locomotor time 10.80.82.21.00.7-1.1-1.1-1.10.8-1.01.10.60.7-0.71.0-0.6-0.3-0.30.3-1.30.60.4-1.41.5
Bouts of movement, locomotor time 10.70.81.1-1.0-1.00.90.90.9-0.91.1-1.0-1.0-1.00.7-1.00.90.80.7-0.70.90.6-0.90.9-0.8
Total resting periods, locomotor time 11.31.51.8-1.3-1.31.21.21.2-1.31.4-1.3-1.3-1.41.2-1.31.41.21.1-1.11.20.9-0.71.1-1.0
Rest time, locomotor task time 10.30.40.9-0.5-0.50.40.40.4-0.60.5-0.5-0.8-0.80.9-0.60.91.00.8-0.80.40.90.40.1-0.1
Distance moved, locomotor task time 10.61.02.81.10.6-1.0-1.0-1.00.9-1.11.10.70.8-0.81.2-0.8-0.5-0.30.3-1.50.50.1-1.61.7
Vertical activity count, locomotor time 10.40.92.10.80.6-0.7-0.7-0.70.8-0.90.91.01.1-1.31.1-1.2-1.4-1.11.1-1.1-0.7-0.8-0.70.8
Time >=10cm from walls, locomotor time 20.60.91.50.80.8-0.8-0.8-0.81.0-0.80.91.11.1-1.20.9-1.1-1.2-1.21.2-0.7-1.2-0.2-0.30.3
Bouts of movement, locomotor time 20.10.21.7-0.0-0.40.00.00.0-0.20.2-0.1-0.5-0.40.3-0.10.50.70.6-0.6-0.31.3-0.3-0.50.6
Total resting periods, locomotor time 20.20.32.20.1-0.4-0.0-0.0-0.0-0.20.10.0-0.5-0.40.3-0.00.50.80.7-0.7-0.41.5-0.2-0.60.7
Rest time, locomotor task time 20.10.20.70.2-0.0-0.2-0.2-0.2-0.0-0.10.2-0.3-0.20.30.00.30.70.6-0.6-0.30.80.6-0.50.5
Distance moved, locomotor task time 20.10.10.4-0.3-0.10.30.30.3-0.10.2-0.30.10.1-0.3-0.2-0.2-0.5-0.40.40.3-0.5-0.70.5-0.5
Vertical activity count, locomotor time 20.71.03.10.60.9-0.6-0.6-0.60.9-0.70.61.21.2-1.30.8-1.3-1.8-1.41.4-0.3-1.6-0.20.0-0.1
Light reinforcement 12.86.89.5-2.8-3.12.92.92.9-2.92.8-2.8-2.9-2.92.7-2.62.72.72.6-2.61.82.3-2.11.8-1.4
Light reinforcement 21.01.52.2-1.3-1.51.31.31.3-1.31.4-1.3-1.5-1.41.2-1.31.31.20.9-0.90.91.0-1.21.0-0.7
Bone: marrow area0.40.81.91.00.5-1.0-1.0-1.00.9-1.01.00.70.8-0.81.1-0.8-0.6-0.60.6-1.40.2-0.5-1.21.3
Bone: maximum diameter0.51.03.9-0.5-1.30.50.50.5-0.90.6-0.5-1.2-1.11.1-0.51.11.31.4-1.4-0.32.0-1.2-0.40.6
Bone: maximum force2.95.17.92.72.1-2.7-2.7-2.72.4-2.62.72.02.1-1.92.6-2.0-1.4-1.61.6-2.8-0.40.8-2.72.7
Bone: maximum moment2.95.17.82.72.1-2.7-2.7-2.72.4-2.62.72.02.1-1.92.6-2.1-1.5-1.61.6-2.8-0.40.8-2.62.7
Mean time between licks in bursts0.71.62.8-1.5-1.61.51.51.5-1.41.4-1.5-1.3-1.31.1-1.21.21.01.0-1.01.00.7-1.71.1-1.1
Mean num. licks in bursts0.40.71.0-0.9-1.00.90.90.9-0.90.8-0.9-1.0-0.90.8-0.80.80.80.7-0.70.51.0-0.70.4-0.3
Cd content in liver0.50.61.7-0.9-1.00.80.80.8-0.90.8-0.9-0.8-0.80.7-0.70.70.50.7-0.70.40.6-1.30.5-0.4
Co content in liver2.93.44.4-2.1-1.92.12.12.1-2.02.1-2.1-1.9-1.91.7-2.01.81.51.5-1.51.90.8-1.31.9-1.8
Cu content in liver0.40.52.00.5-0.1-0.5-0.5-0.50.3-0.60.50.30.4-0.50.9-0.3-0.2-0.00.0-1.30.8-1.0-1.21.4
Fe content in liver0.10.10.50.10.1-0.1-0.1-0.10.2-0.20.10.40.4-0.60.3-0.4-0.7-0.60.6-0.2-0.4-0.7-0.00.0
K content in liver0.70.71.9-0.6-1.00.70.70.7-0.80.8-0.6-1.1-1.01.0-0.70.91.11.0-1.00.21.4-0.70.10.0
Mg content in liver1.01.01.7-0.8-1.10.90.90.9-1.01.0-0.8-1.3-1.21.2-1.01.11.31.3-1.30.71.3-0.30.5-0.4
Mn content in liver1.51.77.6-0.6-1.40.70.70.7-1.10.7-0.6-1.5-1.41.5-0.71.42.01.9-1.9-0.22.8-0.4-0.60.9
Na content in liver0.30.30.80.60.5-0.5-0.5-0.50.5-0.60.60.40.4-0.10.6-0.40.2-0.30.3-0.70.30.7-0.80.9
Rb content in liver0.40.41.70.5-0.1-0.6-0.6-0.60.3-0.50.50.10.2-0.30.7-0.2-0.10.2-0.2-1.20.9-0.9-1.21.3
Se content in liver0.00.00.1-0.1-0.00.10.10.1-0.10.1-0.1-0.2-0.10.0-0.10.00.20.0-0.00.10.30.20.1-0.1
Sr content in liver0.60.52.7-0.8-0.90.80.80.8-0.70.8-0.8-0.6-0.60.3-0.70.50.10.2-0.20.6-0.1-1.70.9-0.8
Zn content in liver3.64.07.2-2.3-1.92.32.32.3-2.02.4-2.3-1.8-1.91.5-2.31.71.11.3-1.32.50.0-1.32.7-2.7
Bone: minimum diameter0.30.51.80.80.1-0.8-0.8-0.80.5-0.70.80.20.3-0.20.8-0.3-0.00.1-0.1-1.30.8-0.6-1.21.3
Time in familiar zone, hab. session 14.54.35.7-2.3-1.92.32.32.3-2.22.3-2.3-2.1-2.22.2-2.42.21.91.9-1.92.41.0-0.22.1-2.1
Time in novel zone, hab. session 13.63.66.12.21.6-2.2-2.2-2.22.0-2.12.21.71.8-1.72.2-1.8-1.3-1.31.3-2.5-0.10.4-2.42.4
Total zone transitions, hab. session 10.40.52.4-0.0-0.30.00.00.0-0.30.1-0.0-0.7-0.60.9-0.20.61.31.3-1.3-0.11.61.0-0.60.7
Total locomotion distance, hab. session 11.42.07.6-0.7-1.30.70.70.7-1.20.8-0.7-1.6-1.51.8-0.81.52.22.3-2.30.12.80.2-0.50.7
Locomotion velocity, hab. session 11.52.16.2-1.0-1.41.01.01.0-1.41.0-1.0-1.7-1.61.8-1.11.62.22.2-2.20.42.50.0-0.10.2
Time in familiar zone, hab. session 25.55.87.7-2.8-2.52.82.82.8-2.62.8-2.8-2.4-2.52.2-2.72.41.81.9-1.92.70.8-1.32.7-2.6
Time in novel zone, hab. session 26.06.18.22.82.4-2.8-2.8-2.82.6-2.82.82.42.5-2.22.8-2.4-1.8-1.81.8-2.9-0.61.2-2.82.8
Total zone transitions, hab. session 21.11.44.41.30.9-1.3-1.3-1.30.9-1.41.30.70.8-0.51.4-0.60.0-0.10.1-1.71.01.0-2.02.1
Total locomotion distance, hab. session 20.30.41.8-0.1-0.20.10.10.1-0.40.0-0.1-0.5-0.50.8-0.10.61.11.0-1.0-0.11.40.9-0.60.6
Locomotion velocity, hab. session 20.40.62.7-0.0-0.20.00.00.0-0.4-0.1-0.0-0.6-0.60.9-0.10.61.31.2-1.2-0.21.61.1-0.80.8
Novel to familiar place preference ratio3.23.55.92.21.8-2.2-2.2-2.21.9-2.22.21.71.8-1.52.2-1.8-1.1-1.11.1-2.4-0.11.0-2.42.4
Novelty place preference2.12.34.31.71.4-1.7-1.7-1.71.5-1.81.71.31.4-1.21.8-1.4-0.8-0.80.8-2.00.00.7-2.12.1
Time in novel zone, NPP test2.62.84.81.91.5-1.9-1.9-1.91.7-2.01.91.61.6-1.42.0-1.6-1.1-1.01.0-2.2-0.20.6-2.22.2
Total zone transitions, NPP test0.81.23.11.31.2-1.3-1.3-1.31.1-1.31.30.90.9-0.61.1-0.8-0.1-0.30.3-1.10.31.8-1.51.4
Total locomotion distance, NPP test0.40.51.60.70.6-0.7-0.7-0.70.5-0.80.70.30.30.00.7-0.30.50.4-0.4-0.80.91.3-1.21.2
Locomotion velocity, NPP test0.20.31.50.40.3-0.4-0.4-0.40.2-0.50.4-0.0-0.00.30.30.00.80.7-0.7-0.51.01.2-0.90.9
Intraocular pressure0.40.62.3-0.70.00.70.70.7-0.40.7-0.7-0.2-0.30.4-0.80.20.00.0-0.01.4-1.10.71.4-1.5
Delta distance traveled before/after self-admin0.80.81.31.11.1-1.0-1.0-1.01.1-0.81.10.90.9-0.90.8-0.9-0.8-1.11.1-0.5-0.70.9-0.60.4
Delta ambulatory time before/after self-admin0.81.01.81.31.1-1.2-1.2-1.21.2-1.11.30.90.9-0.81.0-0.9-0.6-0.80.8-0.9-0.31.0-1.00.9
Parametrial fat weight0.41.01.51.20.9-1.2-1.2-1.21.2-1.01.20.91.0-1.01.1-1.0-0.8-0.90.9-1.1-0.30.2-1.01.0
Pavlov. Cond. lever latency0.30.41.5-0.3-0.00.30.30.30.00.4-0.30.20.2-0.5-0.3-0.3-0.9-0.80.80.6-1.2-0.81.0-1.0
Pavlov. Cond. magazine entry latency1.41.82.4-1.5-1.41.51.51.5-1.51.3-1.5-1.4-1.41.5-1.41.51.41.5-1.51.31.0-0.41.1-1.0
Pavlov. Cond. change in total contacts0.10.10.20.30.2-0.4-0.4-0.40.3-0.40.30.40.4-0.30.5-0.3-0.3-0.10.1-0.5-0.1-0.2-0.40.4
Pavlov. Cond. index score0.40.51.2-0.5-0.50.50.50.5-0.70.4-0.5-0.7-0.70.9-0.50.81.01.1-1.10.31.00.4-0.00.1
Pavlov. Cond. latency score0.40.61.8-0.4-0.60.40.40.4-0.70.3-0.4-0.8-0.81.0-0.40.91.21.2-1.20.11.30.3-0.20.3
Pavlov. Cond. lever contacts0.30.41.20.50.3-0.5-0.5-0.50.2-0.60.50.10.10.30.50.00.60.6-0.6-0.71.01.0-1.11.1
Pavlov. Cond. magazine entry number0.60.81.01.00.8-0.9-0.9-0.91.0-0.81.00.80.9-1.00.9-0.9-0.9-1.01.0-0.9-0.5-0.0-0.80.8
Pavlov. Cond. intertrial magazine entries0.20.20.8-0.6-0.30.60.60.6-0.40.5-0.6-0.1-0.20.1-0.40.2-0.1-0.10.10.7-0.6-0.50.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.3-0.6-0.70.60.60.6-0.80.5-0.6-0.8-0.81.0-0.60.91.11.2-1.20.41.10.20.1-0.0
Pavlov. Cond. response bias0.50.60.9-0.8-0.60.80.80.8-0.80.6-0.8-0.7-0.80.9-0.70.80.91.0-1.00.80.50.30.5-0.5
Pavlov. Cond. lever latency1.41.82.91.31.3-1.3-1.3-1.31.4-1.51.31.61.6-1.71.6-1.5-1.6-1.31.3-1.4-0.80.1-1.21.2
Pavlov. Cond. magazine entry latency1.92.33.5-1.4-1.51.41.41.4-1.51.7-1.4-1.8-1.81.9-1.71.61.81.7-1.71.51.2-0.21.3-1.2
Pavlov. Cond. change in total contacts0.71.11.6-1.1-1.21.11.11.1-1.11.3-1.1-1.2-1.21.1-1.21.10.90.8-0.81.10.5-0.71.1-1.0
Pavlov. Cond. index score1.82.43.3-1.6-1.71.61.61.6-1.61.8-1.6-1.8-1.81.8-1.81.71.61.5-1.51.50.9-0.61.4-1.4
Pavlov. Cond. latency score1.82.43.7-1.5-1.61.51.51.5-1.61.7-1.5-1.8-1.81.9-1.81.71.81.6-1.61.51.1-0.31.3-1.3
Pavlov. Cond. lever contacts1.31.92.6-1.4-1.31.41.41.4-1.41.6-1.4-1.5-1.51.6-1.61.51.41.2-1.21.50.5-0.21.4-1.4
Pavlov. Cond. magazine entry number2.12.63.91.51.7-1.5-1.5-1.51.7-1.71.51.91.9-2.01.7-1.8-1.8-1.81.8-1.4-1.20.5-1.31.2
Pavlov. Cond. intertrial magazine entries0.71.12.30.91.0-0.9-0.9-0.91.1-0.80.91.11.2-1.40.9-1.3-1.4-1.51.5-0.7-1.2-0.0-0.50.4
Pavlov. Cond. lever-magazine prob. diff.2.12.83.8-1.7-1.81.71.71.7-1.71.9-1.7-1.9-1.91.9-1.81.81.71.7-1.71.51.1-0.81.4-1.3
Pavlov. Cond. response bias2.23.04.1-1.8-1.81.81.81.8-1.82.0-1.8-1.9-1.92.0-2.01.81.61.6-1.61.90.7-0.61.8-1.8
Time in closed arm before self-admin0.20.31.10.70.3-0.6-0.6-0.60.4-0.60.60.20.20.00.6-0.00.20.2-0.2-0.90.60.4-1.01.0
Time in closed arm after self-admin0.40.44.60.1-0.4-0.1-0.1-0.10.20.10.20.20.4-0.50.4-0.5-0.8-0.60.6-0.7-0.8-2.2-0.00.2
Time in open arm before self-admin0.30.32.9-0.5-0.80.50.50.5-0.40.6-0.5-0.4-0.3-0.2-0.30.1-0.10.1-0.1-0.00.5-1.70.3-0.1
Time in open arm after self-admin2.12.33.71.61.9-1.6-1.6-1.61.7-1.61.61.71.6-1.71.4-1.7-1.3-1.71.7-0.8-1.01.6-0.90.7
Bone: periosteal estimation0.91.95.31.60.7-1.6-1.6-1.61.2-1.51.60.81.0-0.81.7-1.0-0.5-0.40.4-2.30.8-0.5-2.12.3
Bone: periosteal perimeter0.30.42.30.3-0.5-0.3-0.3-0.3-0.0-0.20.3-0.4-0.30.30.40.20.60.7-0.7-1.01.5-0.8-1.01.3
Bone: post-yield work0.50.71.01.00.8-1.0-1.0-1.01.0-0.91.00.80.8-0.80.9-0.9-0.7-0.70.7-0.8-0.40.3-0.80.7
Progressive ratio test 1 active lever presses0.30.41.70.60.1-0.5-0.5-0.50.6-0.30.70.40.5-0.90.5-0.8-0.8-0.70.7-0.6-0.3-1.3-0.30.3
Progressive ratio test 1 breakpoint0.30.41.70.60.1-0.5-0.5-0.50.6-0.30.70.40.5-0.90.5-0.8-0.9-0.70.7-0.5-0.3-1.3-0.30.3
Progressive ratio test 1 inactive lever presses0.60.95.9-0.9-1.51.01.01.0-0.91.1-0.8-0.9-0.80.4-0.70.70.30.4-0.40.20.6-2.40.6-0.4
Progressive ratio test 2 active lever presses0.30.33.1-0.5-0.90.60.60.6-0.50.6-0.3-0.5-0.50.1-0.40.20.10.2-0.20.00.5-1.80.3-0.1
Progressive ratio test 2 breakpoint0.30.42.6-0.5-0.90.60.60.6-0.50.7-0.4-0.6-0.60.2-0.50.30.20.3-0.30.10.6-1.60.4-0.2
Progressive ratio test 2 inactive lever presses0.20.33.30.2-0.6-0.1-0.1-0.10.10.00.3-0.1-0.0-0.30.3-0.3-0.2-0.10.1-0.80.7-1.8-0.40.7
Incentive Sensitization - Responses0.30.50.7-0.9-0.70.80.80.8-0.80.8-0.8-0.7-0.70.5-0.80.60.50.5-0.50.70.5-0.40.6-0.6
Incentive Sensitization - Breakpoint0.50.60.9-0.9-0.80.80.80.8-0.90.8-0.9-0.8-0.80.7-0.80.80.70.7-0.70.70.7-0.40.6-0.5
Sum of active levers in priming session hrs 5-60.20.20.3-0.5-0.30.50.50.5-0.50.4-0.6-0.3-0.40.5-0.40.40.30.3-0.30.4-0.2-0.10.5-0.5
Progressive ratio0.71.22.80.90.7-0.8-0.8-0.81.0-0.70.91.11.2-1.71.0-1.4-1.5-1.61.6-0.9-0.8-1.0-0.40.5
Food seeking constrained by brief footshock1.41.72.7-1.3-0.61.21.21.2-1.31.0-1.3-1.1-1.31.6-1.41.51.61.5-1.51.60.51.41.1-1.2
Seeking ratio, punishment vs. effort1.82.65.2-1.5-1.01.41.41.4-1.61.3-1.5-1.6-1.72.3-1.72.02.02.0-2.01.80.61.51.2-1.4
Retroperitoneal fat weight1.87.612.22.72.8-2.6-2.6-2.63.1-2.42.63.13.1-3.42.5-3.3-3.5-3.53.5-1.9-3.30.5-1.11.0
Reaction time number correct0.61.12.90.81.3-0.8-0.8-0.81.1-0.90.81.31.2-1.30.8-1.2-1.4-1.51.5-0.3-1.70.7-0.1-0.1
Reaction time mean minus median0.61.42.2-1.3-1.21.21.21.2-1.31.1-1.3-1.3-1.31.5-1.21.41.31.4-1.41.00.9-0.10.8-0.8
Reaction time mean minus median AUC0.61.43.9-0.8-1.00.70.70.7-1.10.7-0.8-1.4-1.31.7-0.81.51.92.0-2.00.41.90.5-0.20.2
Reaction time num false alarms0.60.81.41.00.9-1.0-1.0-1.01.1-0.91.00.90.9-1.20.8-1.2-1.0-1.11.1-0.7-0.60.2-0.50.6
Reaction time num false alarms AUC0.50.81.50.90.9-0.9-0.9-0.91.1-0.80.90.91.0-1.20.7-1.2-1.1-1.21.2-0.6-0.90.2-0.30.3
Reaction time trials correct on left0.61.12.90.81.3-0.8-0.8-0.81.1-0.90.81.31.2-1.30.8-1.2-1.4-1.51.5-0.3-1.70.7-0.1-0.1
Reaction time trials on left0.61.12.60.81.3-0.8-0.8-0.81.1-0.90.81.31.2-1.20.8-1.2-1.4-1.41.4-0.3-1.60.7-0.2-0.0
Reaction time mean0.81.22.9-0.9-0.90.80.80.8-1.20.6-0.9-1.2-1.21.6-0.81.51.61.7-1.70.61.40.60.1-0.2
Reaction time mean AUC0.40.61.6-0.5-0.60.40.40.4-0.80.3-0.5-0.8-0.81.2-0.41.01.21.3-1.30.21.10.4-0.20.1
Median of all reaction times0.50.71.9-0.6-0.60.50.50.5-0.90.3-0.6-0.8-0.91.3-0.51.11.31.4-1.40.31.20.6-0.20.1
Reaction time omissions0.10.10.3-0.0-0.4-0.0-0.0-0.0-0.2-0.0-0.0-0.3-0.20.40.10.30.40.5-0.5-0.50.6-0.5-0.50.6
Reaction time false alarm rate0.20.30.40.70.4-0.7-0.7-0.70.6-0.50.70.30.4-0.50.5-0.6-0.3-0.40.4-0.50.00.2-0.50.6
Reaction time premature initiation rate1.41.93.3-1.7-1.21.71.71.7-1.41.7-1.7-1.2-1.31.1-1.61.10.90.8-0.81.80.2-0.41.7-1.8
Reaction time premature initiations0.61.13.5-1.3-0.51.31.31.3-0.91.2-1.3-0.5-0.60.4-1.20.50.2-0.00.01.7-0.8-0.21.7-1.9
Std. dev. reaction times0.50.82.0-0.7-0.90.60.60.6-0.90.7-0.7-1.1-1.11.2-0.81.11.31.4-1.40.51.20.20.2-0.2
Reaction time trials completed0.61.12.60.81.3-0.8-0.8-0.81.1-0.90.81.31.2-1.20.8-1.2-1.4-1.41.4-0.3-1.60.7-0.2-0.0
Reaction time trials AUC0.71.33.30.81.4-0.9-0.9-0.91.1-0.90.81.41.3-1.40.8-1.3-1.5-1.61.6-0.3-1.80.7-0.1-0.1
Run reversals in cocaine runway, females2.22.24.2-1.3-1.41.21.21.2-1.61.2-1.3-1.7-1.71.7-1.41.82.02.0-2.01.12.00.40.6-0.6
Run reversals in cocaine runway, males2.22.24.0-1.4-1.71.41.41.4-1.71.2-1.4-1.7-1.72.0-1.31.81.91.9-1.90.81.5-0.70.7-0.5
Latency to leave start box in cocaine runway0.60.72.01.00.7-1.0-1.0-1.00.7-0.81.00.20.30.10.8-0.30.60.3-0.3-0.90.91.4-1.41.3
Latency to leave start box in cocaine runway, F1.11.23.71.20.9-1.2-1.2-1.20.8-1.21.10.30.40.21.0-0.40.80.5-0.5-1.21.11.9-1.81.7
Latency to leave start box in cocaine runway, M0.10.10.2-0.0-0.00.10.10.10.10.30.00.00.0-0.2-0.2-0.1-0.3-0.30.30.2-0.4-0.40.3-0.4
Std. dev. time between licks in bursts0.60.92.3-0.8-1.20.80.80.8-1.00.7-0.8-1.1-1.01.1-0.61.11.21.1-1.10.11.5-0.8-0.20.2
Total sessions with >9 infusions0.70.913.20.1-1.10.00.00.00.00.20.3-0.10.1-0.60.4-0.5-0.8-0.70.7-1.20.2-3.6-0.40.7
Short access day 1 total inactive lever presses0.60.81.7-1.2-1.11.11.11.1-1.01.2-1.0-0.8-0.80.5-1.00.80.30.1-0.10.90.1-1.31.1-1.0
Short access day 10 total inactive lever presses0.41.12.6-1.2-0.91.31.31.3-0.81.2-1.0-0.5-0.5-0.1-1.10.4-0.5-0.30.31.2-0.9-1.61.6-1.6
Short access day 1 total infusions0.71.014.4-0.2-1.10.20.20.2-0.10.30.1-0.10.1-0.60.4-0.6-0.8-0.70.7-1.20.2-3.8-0.30.7
Short access day 10 total infusions0.20.34.20.1-0.5-0.0-0.0-0.00.10.10.30.00.1-0.60.2-0.5-0.6-0.50.5-0.50.0-2.0-0.10.2
Short access total infusions0.81.011.00.3-0.7-0.2-0.2-0.20.3-0.20.60.20.4-1.00.7-0.9-0.9-0.90.9-1.50.2-3.3-0.61.0
Short access day 1 locomotion1.31.710.7-1.3-2.01.31.31.3-1.21.6-1.1-1.3-1.10.5-1.20.70.20.4-0.40.60.6-3.31.1-0.9
Short access day 10 total locomotion2.85.315.0-2.7-2.92.82.82.8-2.32.8-2.6-2.0-2.01.0-2.41.50.70.8-0.82.00.5-3.92.5-2.4
Short access total locomotion1.31.69.8-1.3-1.91.41.41.4-1.21.5-1.1-1.1-1.00.4-1.10.60.10.2-0.20.70.4-3.11.1-1.0
One hour access (0.3 mA shock)0.10.11.00.0-0.10.00.00.00.20.00.30.20.3-0.50.1-0.5-0.5-0.50.5-0.2-0.4-1.00.2-0.0
Compulsive drug intake0.00.00.30.10.1-0.1-0.1-0.10.1-0.00.1-0.1-0.10.3-0.00.20.30.1-0.1-0.00.20.5-0.00.1
One hour access (shock baseline)0.30.43.3-0.7-0.90.70.70.7-0.60.7-0.5-0.5-0.4-0.1-0.50.0-0.10.1-0.10.20.2-1.80.5-0.4
Social response proportion0.60.71.6-0.7-0.40.70.70.7-0.90.5-0.7-0.8-0.81.0-0.71.11.30.9-0.90.81.11.20.2-0.3
Social responses7.29.214.1-3.0-2.93.03.03.0-3.33.0-3.0-3.5-3.53.6-3.13.63.83.4-3.42.73.10.31.9-1.8
Social time1.11.52.41.11.5-1.1-1.1-1.11.3-1.31.11.61.5-1.41.3-1.3-1.4-1.41.4-0.8-1.30.9-0.70.5
Soleus weight5.917.320.94.54.5-4.5-4.5-4.54.6-4.64.54.54.6-4.44.4-4.4-4.2-4.24.2-3.7-3.22.0-3.43.1
Bone: stiffness3.86.18.52.92.3-2.9-2.9-2.92.7-2.82.92.42.5-2.42.8-2.4-1.9-2.02.0-2.9-0.70.5-2.72.7
Tibialis anterior weight1.44.65.72.32.4-2.3-2.3-2.32.4-2.42.32.42.4-2.22.3-2.2-2.2-2.02.0-1.9-1.81.1-1.71.6
Time to tail flick, vehicle, before self-admin1.21.32.5-1.1-1.41.11.11.1-1.31.0-1.0-1.2-1.21.6-0.91.41.41.4-1.40.30.7-1.00.4-0.2
Time to tail flick, vehicle, after self-admin0.40.62.1-0.9-0.30.70.70.7-0.60.9-1.0-0.4-0.50.2-1.00.50.30.2-0.21.4-0.50.11.3-1.4
Time to tail flick, test, before self-admin0.60.72.8-0.5-0.90.40.40.4-0.70.5-0.4-1.0-0.90.9-0.40.81.11.3-1.3-0.11.7-0.6-0.30.4
Time to tail flick, test, after self-admin0.00.10.20.1-0.2-0.1-0.1-0.1-0.00.00.1-0.2-0.10.10.10.10.20.1-0.1-0.40.4-0.4-0.40.5
Delta time to tail flick, vehicle, before/after SA1.51.53.10.91.8-1.1-1.1-1.11.3-1.00.81.41.3-1.60.7-1.3-1.3-1.51.50.1-1.61.70.0-0.3
Delta time to tail flick, test, before/after SA0.30.31.8-0.20.30.30.30.30.10.2-0.30.30.2-0.2-0.2-0.1-0.5-0.70.70.7-1.30.50.8-0.9
Tibia length0.72.03.2-1.5-1.21.51.51.5-1.41.5-1.5-1.4-1.51.5-1.71.41.41.4-1.41.80.70.01.5-1.5
Ambulatory time before self-admin0.40.60.9-0.9-0.80.90.90.9-0.90.7-0.9-0.7-0.80.8-0.80.70.70.7-0.70.60.3-0.30.7-0.6
Ambulatory time after self-admin0.10.10.60.30.3-0.2-0.2-0.20.2-0.20.20.10.10.10.1-0.10.1-0.20.2-0.0-0.20.8-0.20.1
Bone: tissue strength4.94.96.52.42.0-2.4-2.4-2.42.3-2.42.42.32.3-2.32.5-2.3-2.0-2.12.1-2.6-1.00.2-2.22.2
Total heroin consumption1.72.03.5-1.4-1.31.31.31.3-1.51.3-1.5-1.6-1.61.8-1.51.71.91.7-1.71.21.40.30.8-0.8
Bone: trabecular number0.30.62.70.2-0.4-0.2-0.2-0.2-0.20.20.2-0.9-0.81.0-0.30.71.41.2-1.2-0.21.60.6-0.50.7
Bone: trabecular spacing0.70.94.2-0.70.00.70.70.7-0.10.5-0.70.50.4-0.8-0.3-0.4-1.4-1.11.11.0-2.1-1.21.5-1.6
Bone: trabecular thickness1.62.08.11.40.3-1.4-1.4-1.40.7-1.21.4-0.00.20.31.3-0.11.00.9-0.9-2.22.50.8-2.62.8
Bone: trabecular tissue density3.95.78.72.42.3-2.4-2.4-2.42.6-2.32.42.72.7-2.82.4-2.8-2.8-2.92.9-2.0-2.30.1-1.51.3
Water consumed over 24 hours0.81.11.91.20.9-1.2-1.2-1.21.1-1.11.20.80.9-0.91.1-1.0-0.6-0.60.6-1.30.20.3-1.41.4
Number of responses in last shaping day4.14.512.6-2.4-2.92.62.62.6-2.32.6-2.3-2.1-2.01.3-2.21.60.91.1-1.11.60.8-3.52.0-1.8