Bloc1s1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Bloc1s1 0.07 0.06 3.0e-06 0.03 0.04 0.06 0.04 1.8e-04 2.2e-05 4.7e-07 1.7e-05
2 OFC mRNA stability Bloc1s1 0.19 0.12 3.0e-03 0.09 0.07 0.1 0.08 4.7e-03 8.4e-03 2.9e-03 4.9e-03
3 BLA gene expression Bloc1s1 0.13 0.08 7.1e-07 0.12 0.11 0.1 0.11 3.8e-07 2.4e-06 3.0e-06 2.4e-06
4 Brain gene expression Bloc1s1 0.11 0.07 6.2e-07 0.06 0.06 0.07 0.06 6.2e-06 1.2e-06 8.9e-07 1.2e-06
5 PL mRNA stability Bloc1s1 0.31 0.18 0.0e+00 0.21 0.2 0.21 0.21 9.6e-23 1.5e-21 4.7e-23 8.1e-23
6 PL gene expression Bloc1s1 0.05 0.04 1.8e-04 0.03 0.02 0.03 0.03 1.6e-04 1.1e-03 5.9e-04 8.0e-04
7 Eye intron excision ratio chr7_1348296_1350200 0.37 0.19 1.9e-03 0.19 0.15 0.13 0.18 8.2e-04 2.6e-03 5.0e-03 1.1e-03
8 LHb mRNA stability Bloc1s1 0.39 0.17 5.4e-07 0.24 0.27 0.29 0.28 2.1e-06 3.3e-07 1.6e-07 1.9e-07
9 Brain mRNA stability Bloc1s1 0.31 0.15 0.0e+00 0.18 0.17 0.18 0.18 2.1e-16 1.6e-15 2.5e-16 2.2e-16
10 NAcc mRNA stability Bloc1s1 0.13 0.07 6.3e-11 0.1 0.09 0.09 0.1 1.3e-11 2.9e-10 4.8e-11 2.2e-11
11 IL gene expression Bloc1s1 0.21 0.14 5.6e-03 0.07 0.03 0.04 0.05 9.8e-03 7.8e-02 3.8e-02 2.0e-02
12 IL mRNA stability Bloc1s1 0.43 0.18 9.7e-06 0.12 0.11 0.12 0.11 1.0e-03 1.2e-03 1.0e-03 1.1e-03
13 Adipose gene expression Bloc1s1 0.05 0.04 1.6e-05 0.02 0.03 0.03 0.03 1.8e-03 5.0e-04 9.3e-05 3.1e-04
14 BLA mRNA stability Bloc1s1 0.37 0.23 4.1e-09 0.16 0.14 0.16 0.15 5.4e-09 4.7e-08 5.0e-09 1.5e-08
15 OFC gene expression Bloc1s1 0.23 0.13 1.0e-03 0.12 0.14 0.13 0.13 8.7e-04 3.8e-04 4.6e-04 4.8e-04
16 Adipose mRNA stability Bloc1s1 0.07 0.05 8.6e-06 0.02 0.05 0.05 0.05 1.0e-03 3.2e-06 1.5e-06 2.8e-06
17 NAcc gene expression Bloc1s1 0.04 0.03 1.2e-03 0.02 0.02 0.02 0.02 1.6e-03 2.4e-03 7.6e-04 4.4e-03
18 LHb gene expression Bloc1s1 0.18 0.12 4.5e-03 0.07 0.08 0.01 0.05 1.2e-02 6.2e-03 1.6e-01 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.91.64.9-0.60.7-1.10.2-0.30.90.9-0.2-1.0-1.00.7-0.8-2.1-0.6-1.6-2.02.1-2.2
Area under the delay curve0.40.41.9-0.1-0.80.30.2-0.50.60.6-0.6-0.7-0.70.7-0.30.7-1.4-0.7-0.50.3-0.7
BMI with tail6.922.327.25.1-5.04.85.2-5.25.25.2-5.2-5.2-5.25.1-5.13.5-4.2-4.3-3.93.7-3.3
BMI without tail1.22.53.81.9-1.91.91.8-1.81.61.7-1.8-1.7-1.71.6-1.61.6-1.3-1.1-0.90.8-0.6
Body weight1.45.97.92.4-2.82.62.5-2.62.62.7-2.7-2.6-2.62.7-2.42.4-2.7-2.1-1.81.5-1.5
Weight adjusted by age0.10.10.40.3-0.10.30.10.2-0.3-0.30.10.20.2-0.30.20.20.40.50.4-0.50.6
Bone surface1.62.813.3-1.41.8-2.2-0.40.20.50.50.4-0.6-0.60.3-0.7-3.60.2-1.8-2.52.8-2.8
Bone volume1.72.911.1-1.21.5-2.0-0.1-0.10.90.90.1-1.0-1.00.6-0.9-3.3-0.2-2.1-2.72.9-3.0
Breakpoint value in progressive ratio session2.52.74.1-1.41.4-1.2-1.51.8-2.0-2.01.71.91.9-1.81.7-0.51.71.71.7-1.61.6
Number of licking bursts2.83.35.92.2-2.42.42.0-2.01.81.8-2.1-1.8-1.81.9-1.82.0-1.8-1.1-0.80.7-0.5
Context. condit. distance diff. score0.20.20.40.5-0.50.60.5-0.50.40.4-0.6-0.4-0.40.5-0.50.5-0.4-0.3-0.30.2-0.2
Locomotion velocity, session 10.80.82.1-0.1-0.4-0.00.4-0.70.90.9-0.7-0.8-0.80.9-0.7-0.2-1.4-1.3-1.31.2-1.5
Locomotion distance, session 10.40.51.5-0.80.6-1.0-0.30.20.10.10.1-0.1-0.10.2-0.1-1.2-0.4-0.8-1.01.1-1.2
Locomotion velocity, session 21.11.34.9-1.51.7-1.9-1.11.1-0.8-0.81.10.80.8-0.70.6-2.20.8-0.2-0.60.7-0.8
Locomotion distance, session 21.31.85.4-2.31.8-2.2-1.71.5-1.0-1.01.41.01.0-1.11.3-2.00.20.3-0.00.0-0.4
Locomotion velocity, session 34.35.06.5-2.42.3-2.1-2.62.4-2.4-2.42.42.52.5-2.42.5-1.41.82.11.9-1.91.6
Locomotion distance, session 30.10.10.2-0.20.1-0.0-0.30.2-0.2-0.20.20.30.3-0.30.30.1-0.00.40.3-0.40.4
Stereotopy head waving bouts, day 35.36.39.2-2.83.0-2.9-2.82.8-2.6-2.62.92.62.6-2.72.6-2.42.42.01.7-1.41.3
Stereotopy head waving duration, day 34.45.27.9-2.32.8-2.6-2.42.6-2.4-2.42.62.32.3-2.52.2-2.52.81.81.4-1.11.2
Locomotion velocity, session 70.10.10.3-0.40.4-0.5-0.40.3-0.3-0.30.20.30.3-0.10.1-0.60.1-0.1-0.20.2-0.2
Locomotion distance, session 70.10.10.40.4-0.40.50.2-0.1-0.0-0.0-0.20.00.00.1-0.10.60.00.40.4-0.50.6
Stereotopy head waving bouts, day 70.50.51.6-1.21.1-1.2-0.90.6-0.5-0.50.80.50.5-0.50.6-1.10.0-0.1-0.20.3-0.5
Stereotopy head waving duration, day 70.30.41.5-1.20.9-1.1-0.70.4-0.2-0.20.50.30.3-0.20.4-1.0-0.4-0.4-0.40.5-0.8
Locomotion velocity, session 80.60.72.6-1.61.1-1.5-1.00.7-0.3-0.30.70.30.3-0.30.6-1.4-0.4-0.4-0.50.5-0.9
Locomotion distance, session 80.10.20.7-0.90.5-0.6-0.60.4-0.3-0.30.40.30.3-0.30.5-0.5-0.20.10.0-0.1-0.1
Degree of sensitization distance0.50.50.70.7-0.80.60.8-0.70.70.7-0.9-0.8-0.80.8-0.80.5-0.6-0.7-0.60.6-0.6
Degree of sensitization stereotypy0.50.51.60.0-0.40.20.4-0.70.80.8-0.6-0.7-0.70.8-0.60.2-1.3-1.0-0.90.9-1.1
Conditioned locomotion0.91.13.71.5-1.61.71.0-1.00.70.7-1.1-0.7-0.70.9-0.61.9-1.0-0.10.2-0.30.4
Cocaine response after cond. corrected1.51.74.31.9-1.92.11.5-1.41.21.2-1.5-0.9-0.91.3-1.21.8-1.0-0.5-0.20.10.2
Cocaine response after cond. not corrected1.51.64.32.0-1.92.11.5-1.41.11.1-1.4-1.0-1.01.1-1.11.9-0.8-0.3-0.1-0.00.3
Cocaine response before conditioning0.50.61.3-0.91.1-1.0-0.70.8-0.8-0.81.00.60.6-0.90.8-0.70.90.50.4-0.40.2
Saline control response0.40.50.90.8-0.80.90.7-0.80.80.8-0.7-0.7-0.70.6-0.61.0-0.8-0.4-0.20.2-0.2
Bone: connectivity density0.50.83.0-0.50.6-1.00.1-0.10.60.6-0.0-0.6-0.60.4-0.5-1.7-0.2-1.1-1.51.5-1.6
Bone: cortical apparent density1.11.42.21.3-1.11.21.5-1.31.31.3-1.3-1.3-1.31.2-1.40.6-0.7-1.0-1.01.0-0.7
Bone: cortical area1.21.84.90.7-0.20.11.1-1.11.31.3-1.0-1.3-1.31.3-1.6-1.0-0.6-1.8-2.12.2-2.0
Bone: cortical porosity0.20.21.4-0.30.7-0.7-0.20.3-0.2-0.20.40.20.2-0.2-0.1-1.20.7-0.2-0.50.5-0.4
Bone: cortical porosity0.40.41.70.10.5-0.50.2-0.20.40.4-0.0-0.3-0.30.3-0.6-1.30.4-0.7-1.11.2-1.0
Bone: cortical thickness1.32.13.51.3-0.90.91.6-1.51.51.5-1.4-1.6-1.61.6-1.8-0.0-0.8-1.7-1.81.9-1.6
Bone: cortical thickness0.60.71.41.2-1.21.10.9-1.00.80.8-1.0-0.8-0.80.9-0.91.1-0.6-0.5-0.40.3-0.2
Bone: cortical tissue density0.71.01.61.1-0.91.11.3-1.11.11.1-1.1-1.1-1.11.0-1.20.6-0.6-0.8-0.80.8-0.5
Condit. Reinf. active minus inactive responses2.02.32.9-1.61.7-1.6-1.71.7-1.7-1.71.61.71.7-1.61.5-1.51.61.21.0-0.90.8
Condit. Reinf. active-inactive response ratio0.60.71.7-0.40.7-0.5-0.70.8-1.0-1.00.80.90.9-0.90.7-0.51.30.90.8-0.70.9
Condit. Reinf. active responses2.42.94.9-2.22.2-2.2-2.01.9-1.8-1.81.91.81.8-1.71.6-2.21.61.00.7-0.60.4
Condit. Reinf. inactive responses0.91.02.7-1.71.4-1.6-1.31.1-0.9-0.91.10.90.9-0.80.9-1.60.40.2-0.00.1-0.3
Incentive salience index mean0.91.12.4-1.51.4-1.5-1.31.2-1.1-1.11.11.11.1-0.91.0-1.60.80.40.2-0.2-0.0
Condit. Reinf. lever presses0.40.62.0-1.00.5-0.8-0.3-0.00.30.3-0.0-0.3-0.30.4-0.1-1.1-1.0-1.0-1.21.1-1.4
Condit. Reinf. active minus inactive responses2.93.65.1-1.21.5-1.4-1.82.0-2.2-2.22.02.12.1-2.22.0-0.92.32.12.0-1.91.9
Condit. Reinf. active-inactive response ratio1.41.53.5-0.20.2-0.1-0.91.0-1.3-1.30.91.31.3-1.21.20.61.21.71.8-1.91.8
Condit. Reinf. active responses2.02.74.6-1.31.8-1.5-1.61.8-1.8-1.81.91.81.8-1.91.6-1.72.11.51.3-1.11.2
Condit. Reinf. inactive responses0.40.52.1-0.81.1-1.0-0.70.7-0.5-0.50.80.60.6-0.70.5-1.50.80.2-0.00.2-0.1
Condit. Reinf. lever presses3.24.35.8-1.71.9-1.6-2.02.2-2.2-2.22.32.12.1-2.42.3-1.22.22.22.2-1.91.9
Condit. Reinf. lever reinforcers received1.62.23.7-1.01.4-1.2-1.41.6-1.7-1.61.61.61.6-1.71.5-1.21.91.51.3-1.11.3
Conditioned reinforcement - actives0.60.63.7-0.21.2-1.0-0.00.5-0.4-0.30.70.20.2-0.5-0.0-1.91.6-0.1-0.50.8-0.4
Conditioned reinforcement - inactives0.40.42.21.5-0.30.91.2-0.30.10.1-0.2-0.3-0.3-0.0-0.70.21.40.20.00.10.5
Conditioned locomotion4.55.412.8-1.82.9-2.6-1.82.6-2.5-2.52.72.32.3-2.61.9-3.03.61.81.2-0.81.1
Patch foraging indifference point 0 sec3.04.87.02.4-1.92.02.6-2.42.42.4-2.3-2.4-2.42.3-2.60.9-1.4-2.2-2.22.2-1.9
Patch foraging indifference point AUC0.40.40.7-0.90.4-0.7-0.90.7-0.6-0.60.50.70.7-0.60.8-0.00.20.70.7-0.70.6
Delay disc. indifference point, 0s delay3.33.66.60.6-1.40.81.3-1.82.12.1-1.8-2.2-2.22.1-1.70.4-2.6-2.4-2.32.1-2.5
Delay disc. indifference point, 16s delay0.10.10.3-0.6-0.0-0.3-0.60.3-0.4-0.40.20.40.4-0.20.40.2-0.30.10.3-0.30.0
Delay disc. indifference point, 2s delay0.80.93.20.1-0.90.50.5-0.91.01.0-0.9-1.1-1.11.1-0.80.4-1.8-1.1-1.00.9-1.1
Delay disc. indifference point, 24s delay0.90.92.70.5-1.30.80.7-1.00.90.9-1.0-1.1-1.11.0-0.61.2-1.6-0.9-0.60.4-0.7
Delay disc. indifference point, 4s delay0.20.20.8-0.90.4-0.8-0.50.20.00.00.3-0.0-0.0-0.10.3-0.7-0.5-0.3-0.40.4-0.6
Delay disc. indifference point, 8s delay0.40.41.60.5-1.10.80.4-0.50.50.5-0.6-0.6-0.60.4-0.11.2-0.9-0.10.2-0.40.2
Indifference point function ln k0.10.10.30.5-0.00.20.3-0.20.00.0-0.1-0.1-0.10.1-0.4-0.30.5-0.1-0.30.4-0.1
Indifference point function log k0.10.10.30.5-0.00.20.3-0.20.00.0-0.1-0.1-0.10.1-0.4-0.30.5-0.1-0.30.4-0.1
Patch foraging total patch changes 0 sec2.64.26.32.3-1.91.92.5-2.22.22.2-2.2-2.2-2.22.2-2.50.9-1.2-2.0-2.02.0-1.6
Patch foraging total patch changes 12 sec1.41.83.11.8-1.61.71.7-1.51.41.4-1.5-1.5-1.51.3-1.41.5-0.9-0.8-0.60.6-0.4
Patch foraging total patch changes 18 sec0.10.10.40.2-0.30.20.2-0.20.20.2-0.3-0.2-0.20.3-0.20.6-0.3-0.2-0.10.0-0.2
Patch foraging total patch changes 24 sec0.81.01.30.7-0.90.81.1-1.11.11.1-1.0-1.1-1.11.1-1.00.9-1.1-1.0-0.90.8-0.9
Patch foraging total patch changes 6 sec1.52.23.21.7-1.41.31.7-1.61.61.6-1.6-1.5-1.51.6-1.80.6-0.8-1.4-1.51.5-1.2
Patch foraging time to switch 0 sec0.50.81.40.4-0.30.30.8-0.91.11.1-0.6-1.2-1.21.0-0.7-0.1-1.0-1.1-1.11.0-1.2
Patch foraging water rate 0 sec0.30.41.31.1-1.01.10.8-0.50.30.3-0.7-0.3-0.30.4-0.61.10.00.10.1-0.20.5
Patch foraging water rate 12 sec0.40.62.01.3-1.21.41.0-0.80.40.4-0.9-0.4-0.40.5-0.71.3-0.1-0.00.1-0.10.4
Patch foraging water rate 18 sec0.91.24.20.6-0.50.9-0.20.4-1.0-0.90.30.90.9-0.90.61.41.11.51.8-1.82.0
Patch foraging water rate 24 sec1.21.77.52.0-1.92.41.2-0.90.30.3-1.1-0.3-0.30.5-0.52.7-0.20.71.0-1.21.5
Patch foraging water rate 6 sec1.42.14.3-0.30.8-0.2-0.91.3-1.6-1.61.21.71.7-1.61.20.22.01.91.9-1.82.1
Seeking ratio, delayed vs. immediate footshock1.61.83.6-1.51.9-1.8-1.31.5-1.3-1.31.61.21.2-1.41.1-1.91.70.80.6-0.10.3
Distance traveled before self-admin0.70.71.3-1.11.0-0.9-1.01.0-0.9-0.90.90.90.9-0.81.0-0.50.60.70.6-0.60.5
Distance traveled after self-admin0.20.20.6-0.60.8-0.6-0.30.5-0.5-0.40.60.30.3-0.50.4-0.60.60.30.2-0.00.0
Extensor digitorum longus weight4.618.327.45.2-5.05.24.9-4.84.54.6-4.7-4.6-4.64.4-4.34.3-3.6-3.1-2.62.3-1.9
Bone: elastic displacement0.00.00.2-0.10.1-0.2-0.10.1-0.2-0.20.10.20.2-0.1-0.0-0.40.2-0.1-0.20.2-0.2
Bone: elastic work0.81.01.60.7-0.70.60.9-1.11.11.1-1.0-1.1-1.11.2-1.10.1-1.0-1.2-1.31.3-1.2
Bone: endosteal estimation0.51.22.70.9-0.40.41.0-1.01.11.1-0.9-1.1-1.11.1-1.4-0.6-0.4-1.3-1.61.6-1.4
Bone: endosteal perimeter0.30.73.6-0.91.3-1.3-0.80.7-0.5-0.50.80.50.5-0.50.3-1.90.9-0.2-0.50.7-0.6
Epididymis fat weight0.10.20.5-0.3-0.0-0.0-0.40.3-0.4-0.40.20.40.4-0.30.50.5-0.00.50.6-0.70.6
Delta time in closed arm before/after self-admin0.80.82.81.4-1.01.40.7-0.3-0.1-0.1-0.40.00.0-0.1-0.11.70.70.81.1-1.11.4
Delta time in open arm before/after self-admin2.62.54.81.0-1.61.31.4-1.71.81.8-1.7-1.8-1.81.9-1.41.4-2.2-1.5-1.31.1-1.3
Diff in mean of infusions in LGA sessions2.52.73.8-1.51.7-1.6-1.61.8-2.0-1.91.81.81.8-1.81.7-1.11.91.51.4-1.21.2
Delay discount exponential model param0.30.41.90.10.8-0.3-0.20.5-0.5-0.50.60.70.7-0.60.2-0.71.40.60.4-0.20.6
Extinction: sum of active levers before priming3.23.25.3-1.41.0-1.0-1.81.8-1.9-1.91.72.02.0-1.92.10.31.22.12.3-2.32.1
Active lever presses in extinction session 60.60.61.4-1.20.8-0.9-1.10.9-0.8-0.80.80.80.8-0.81.0-0.60.10.60.5-0.60.3
Bone: final force3.25.17.21.8-1.51.32.2-2.32.52.5-2.2-2.6-2.62.5-2.50.3-1.9-2.6-2.72.7-2.5
Bone: final moment3.04.97.01.7-1.41.32.2-2.22.52.5-2.1-2.5-2.52.4-2.50.2-1.8-2.5-2.62.6-2.5
Food consumed during 24 hour testing period0.40.50.70.7-0.70.60.8-0.70.80.8-0.7-0.8-0.80.7-0.70.4-0.6-0.7-0.60.6-0.6
Glucose1.82.83.71.8-1.91.81.9-1.91.71.7-1.9-1.7-1.71.8-1.81.6-1.6-1.5-1.31.1-1.1
Heart weight0.10.10.40.20.10.10.00.2-0.2-0.20.10.20.2-0.2-0.00.10.70.40.3-0.30.5
Delay discount hyperbolic model param0.50.62.4-0.00.9-0.4-0.40.7-0.7-0.70.70.90.9-0.80.4-0.71.50.80.6-0.40.7
Intermittent access intake day 1-15 change1.51.55.8-0.31.4-0.8-0.51.2-1.4-1.51.31.21.2-1.40.8-1.22.41.10.9-0.51.0
Intermittent access intake escalation1.61.65.50.10.8-0.1-0.31.1-1.5-1.51.11.31.3-1.50.9-0.12.31.51.5-1.11.6
Intermittent access intake escalation 22.22.14.9-0.41.0-0.4-0.81.4-1.8-1.81.41.71.7-1.71.3-0.22.21.71.7-1.41.7
Intermitt. access day 1 inactive lever presses1.01.13.90.30.5-0.0-0.30.9-1.1-1.20.91.11.1-1.30.8-0.12.01.31.2-1.11.5
Intermitt. access day 15 inactive lever presses1.82.03.9-0.51.1-0.6-1.01.4-1.7-1.71.51.61.6-1.71.4-0.62.01.61.4-1.31.6
Intermitt. access escalation Index0.80.74.4-0.61.2-1.1-0.10.4-0.1-0.10.50.10.1-0.2-0.2-2.11.0-0.5-0.81.2-0.9
Intermittent access day 1 total infusions0.40.50.90.5-0.40.30.8-0.70.80.8-0.6-0.9-0.90.7-0.8-0.1-0.3-0.8-0.70.9-0.8
Intermittent access day 15 total infusions0.10.21.50.50.30.10.60.1-0.2-0.20.2-0.0-0.0-0.3-0.2-0.41.20.20.20.20.2
Intermittent access terminal intake (last 3 days)0.20.21.20.20.5-0.20.6-0.10.00.00.1-0.3-0.30.0-0.5-1.10.9-0.3-0.50.9-0.5
Intermittent access total infusions0.20.20.90.7-0.20.40.9-0.50.40.4-0.3-0.6-0.60.3-0.6-0.20.4-0.4-0.40.6-0.3
Intermittent access day 1 locomotion0.00.00.00.1-0.10.00.2-0.10.10.1-0.0-0.2-0.20.00.00.00.0-0.00.1-0.0-0.0
Intermittent access day 15 total locomotion1.41.55.6-0.51.4-1.0-0.61.3-1.4-1.41.41.21.2-1.50.9-1.22.41.20.9-0.61.0
Intermittent access total locomotion0.30.40.9-0.50.8-0.7-0.30.7-0.6-0.60.80.40.4-0.70.6-0.81.00.50.4-0.20.3
Intermittent access standard deviation0.91.04.4-0.11.0-0.6-0.41.0-1.2-1.31.10.90.9-1.20.7-0.92.11.00.7-0.50.9
Left kidney weight0.30.92.5-0.1-0.0-0.30.3-0.60.80.8-0.6-0.8-0.80.9-0.9-0.8-0.8-1.3-1.51.5-1.6
Right kidney weight0.30.82.6-0.91.2-1.3-0.90.9-0.8-0.80.90.80.8-0.70.5-1.61.10.2-0.00.2-0.2
Cocaine induced anxiety0.80.92.8-1.71.3-1.5-1.31.0-0.8-0.81.00.80.8-0.81.0-1.30.20.20.1-0.0-0.3
Post-drug Anxiety0.50.51.6-1.10.8-1.1-0.40.10.20.20.2-0.2-0.20.2-0.0-1.2-0.5-0.8-0.91.0-1.3
Baseline Anxiety0.00.00.10.2-0.10.30.1-0.0-0.0-0.0-0.0-0.0-0.0-0.10.00.30.10.30.2-0.30.4
Tail length4.413.217.0-3.63.4-3.2-3.93.9-4.0-4.03.94.04.0-4.04.1-1.73.13.73.6-3.53.2
Length with tail1.24.36.4-2.52.0-2.2-2.42.3-2.3-2.32.22.32.3-2.12.4-1.21.41.91.7-1.71.4
Length without tail0.30.61.60.1-0.30.10.4-0.60.90.8-0.7-0.8-0.80.9-0.8-0.2-0.9-1.1-1.11.1-1.3
Times rat made contact with spout0.91.02.21.3-1.51.31.2-1.11.01.0-1.2-1.0-1.00.9-1.01.2-0.8-0.5-0.40.2-0.1
Lifetime Intake0.70.82.00.9-0.20.51.4-0.80.80.8-0.6-1.0-1.00.7-1.2-0.50.2-0.9-1.01.3-0.9
Liver weight, left1.01.53.21.8-1.61.51.5-1.31.21.3-1.4-1.2-1.21.3-1.41.1-0.6-0.9-0.70.8-0.5
Liver weight, right0.71.21.81.3-1.10.81.3-1.21.01.0-1.2-1.2-1.21.2-1.30.5-0.6-1.1-1.11.1-1.0
Locomotor activity2.23.56.6-2.52.1-2.6-2.42.1-1.9-1.92.11.91.9-1.92.0-2.01.31.21.0-0.90.5
Locomotor testing distance1.01.63.0-1.61.4-1.7-1.51.4-1.3-1.31.41.31.3-1.21.3-1.51.10.80.7-0.50.3
Locomotor testing rearing0.00.00.20.2-0.40.2-0.00.0-0.1-0.1-0.00.10.1-0.10.20.4-0.10.20.3-0.40.3
Locomotion in novel chamber0.10.10.30.5-0.20.30.5-0.30.20.2-0.2-0.4-0.40.2-0.50.00.3-0.3-0.30.4-0.2
Locomotion in novel chamber post-restriction3.03.64.8-2.21.8-2.0-2.22.1-2.1-2.12.02.12.1-1.92.1-1.11.41.81.8-1.51.4
Fecal boli incidents, locomotor time 10.70.82.81.1-1.41.40.8-0.90.70.7-1.0-0.7-0.70.7-0.51.7-1.1-0.10.2-0.40.3
Change in fecal boli incidents, locomotor task0.50.51.8-1.01.2-1.2-0.70.5-0.3-0.30.60.30.3-0.30.2-1.30.4-0.3-0.50.6-0.7
Time >=10cm from walls, locomotor time 11.01.02.10.5-0.60.30.8-0.91.11.1-0.9-1.1-1.11.1-1.0-0.3-1.0-1.3-1.51.4-1.4
Bouts of movement, locomotor time 10.50.60.8-0.60.5-0.7-0.90.8-0.8-0.80.80.80.8-0.90.9-0.60.80.80.6-0.70.7
Total resting periods, locomotor time 11.01.11.6-1.10.9-1.1-1.21.2-1.1-1.11.21.11.1-1.11.2-0.90.81.00.8-0.90.7
Rest time, locomotor task time 10.20.20.6-0.80.5-0.7-0.70.5-0.4-0.40.60.50.5-0.50.6-0.60.00.30.2-0.30.0
Distance moved, locomotor task time 10.90.92.40.6-0.10.20.9-0.80.90.9-0.8-1.0-1.01.0-1.2-0.5-0.4-1.3-1.51.5-1.4
Vertical activity count, locomotor time 10.60.61.41.2-0.60.91.1-0.80.70.7-0.8-0.7-0.70.7-1.10.40.2-0.6-0.60.7-0.4
Time >=10cm from walls, locomotor time 20.70.81.61.3-1.21.21.1-1.00.80.8-1.0-1.0-1.00.8-0.90.9-0.5-0.5-0.40.4-0.2
Bouts of movement, locomotor time 20.20.31.4-0.70.4-0.9-0.60.4-0.2-0.20.50.10.1-0.20.3-1.20.1-0.3-0.60.4-0.7
Total resting periods, locomotor time 20.30.31.7-0.70.5-0.9-0.50.3-0.1-0.10.40.00.0-0.20.2-1.30.0-0.4-0.70.6-0.8
Rest time, locomotor task time 20.10.10.5-0.40.3-0.4-0.0-0.00.20.20.0-0.2-0.20.2-0.0-0.6-0.4-0.5-0.60.5-0.7
Distance moved, locomotor task time 20.10.10.50.5-0.20.40.20.0-0.2-0.2-0.00.20.2-0.20.00.50.50.50.5-0.50.7
Vertical activity count, locomotor time 20.90.92.51.5-1.41.61.2-1.00.80.8-1.1-0.7-0.70.8-0.91.6-0.3-0.2-0.0-0.10.3
Light reinforcement 13.76.79.2-2.63.0-2.7-2.62.9-2.9-2.92.92.92.9-2.82.6-2.22.82.21.8-1.71.6
Light reinforcement 21.11.52.3-1.11.5-1.2-1.21.3-1.4-1.41.41.41.4-1.41.2-1.01.41.10.9-0.80.8
Bone: marrow area0.51.02.40.8-0.40.40.9-0.91.01.0-0.9-1.1-1.11.1-1.3-0.5-0.4-1.3-1.51.6-1.3
Bone: maximum diameter0.51.05.1-1.11.5-1.5-0.80.7-0.5-0.50.80.50.5-0.50.2-2.30.9-0.3-0.71.0-0.9
Bone: maximum force3.15.37.22.0-1.61.52.3-2.42.62.6-2.2-2.6-2.62.5-2.60.4-1.9-2.6-2.72.7-2.4
Bone: maximum moment3.05.17.11.9-1.61.52.3-2.32.52.5-2.2-2.5-2.52.5-2.60.3-1.8-2.6-2.62.7-2.4
Mean time between licks in bursts1.21.72.5-1.11.2-1.0-1.21.4-1.4-1.41.41.41.4-1.41.3-1.11.61.51.4-1.11.3
Mean num. licks in bursts0.60.71.4-1.01.1-1.2-0.91.0-0.9-0.91.00.90.9-0.90.9-0.80.80.60.4-0.50.3
Cd content in liver0.40.50.70.5-0.70.60.7-0.70.70.7-0.8-0.9-0.90.8-0.70.5-0.7-0.7-0.40.6-0.6
Co content in liver1.41.62.2-1.01.1-0.9-1.21.3-1.4-1.41.31.21.2-1.41.4-0.61.41.51.5-1.31.3
Cu content in liver1.11.43.50.8-0.50.31.1-1.01.01.0-1.0-1.1-1.11.2-1.5-0.6-0.4-1.6-1.81.9-1.6
Fe content in liver0.30.40.90.9-0.70.90.9-0.60.60.6-0.6-0.8-0.80.5-0.60.6-0.2-0.2-0.20.10.1
K content in liver0.50.51.8-0.91.2-1.2-0.60.7-0.5-0.50.80.40.4-0.60.5-1.30.60.0-0.20.3-0.4
Mg content in liver0.30.31.1-0.90.8-1.0-0.50.30.10.10.4-0.1-0.1-0.10.2-1.0-0.2-0.4-0.60.6-0.8
Mn content in liver1.01.15.2-1.21.4-1.6-0.50.40.00.00.6-0.2-0.2-0.1-0.0-2.30.0-1.0-1.51.5-1.7
Na content in liver0.30.31.00.1-0.30.20.5-0.50.50.5-0.5-0.6-0.60.6-0.40.1-1.0-0.8-0.80.6-0.8
Rb content in liver0.70.92.90.50.3-0.20.7-0.60.70.7-0.3-0.9-0.90.6-1.0-1.10.4-1.3-1.51.7-1.5
Se content in liver0.00.00.1-0.20.3-0.3-0.10.10.00.00.2-0.1-0.1-0.10.2-0.3-0.00.0-0.10.0-0.1
Sr content in liver0.90.82.1-0.00.4-0.1-0.40.7-1.0-1.00.71.01.0-0.90.7-0.11.31.31.2-1.21.4
Zn content in liver2.62.96.1-0.90.7-0.6-1.51.6-1.8-1.81.41.81.8-1.81.90.41.32.32.4-2.52.4
Bone: minimum diameter0.40.72.30.20.2-0.20.4-0.50.70.7-0.4-0.8-0.80.7-0.9-1.10.0-1.1-1.41.5-1.3
Time in familiar zone, hab. session 14.74.46.0-2.11.9-1.8-2.32.3-2.3-2.32.22.32.3-2.32.4-0.91.62.22.1-2.11.9
Time in novel zone, hab. session 14.14.05.91.5-1.41.21.9-2.02.22.2-1.9-2.2-2.22.1-2.30.2-1.6-2.4-2.42.4-2.3
Total zone transitions, hab. session 10.30.41.3-1.10.8-1.1-0.50.4-0.1-0.10.40.10.1-0.10.3-1.1-0.4-0.4-0.60.6-0.8
Total locomotion distance, hab. session 11.11.65.7-2.11.9-2.1-1.41.2-0.8-0.81.20.70.7-0.80.8-2.40.4-0.2-0.60.7-1.0
Locomotion velocity, hab. session 11.21.74.7-2.11.9-2.1-1.51.3-1.0-1.01.41.01.0-1.01.1-2.20.60.2-0.10.3-0.5
Time in familiar zone, hab. session 25.86.07.5-2.02.2-1.9-2.52.5-2.7-2.72.62.72.7-2.72.7-1.12.42.72.6-2.52.4
Time in novel zone, hab. session 26.46.48.12.1-2.21.82.5-2.62.72.7-2.6-2.8-2.82.8-2.80.9-2.3-2.9-2.82.7-2.6
Total zone transitions, hab. session 21.31.74.10.2-0.50.10.8-1.01.21.2-1.0-1.2-1.21.3-1.3-0.5-1.4-1.8-2.01.9-2.0
Total locomotion distance, hab. session 20.20.30.9-0.90.5-0.8-0.50.3-0.1-0.10.20.10.10.00.2-0.9-0.5-0.5-0.60.6-0.8
Locomotion velocity, hab. session 20.30.41.1-1.10.6-1.0-0.50.20.00.00.20.00.00.10.1-1.0-0.6-0.7-0.80.8-1.1
Novel to familiar place preference ratio3.83.95.71.3-1.41.11.9-2.02.12.1-1.9-2.1-2.12.2-2.10.4-1.9-2.4-2.42.4-2.3
Novelty place preference2.52.64.21.0-1.00.81.5-1.61.71.7-1.5-1.7-1.71.8-1.80.1-1.5-2.0-2.02.1-2.0
Time in novel zone, NPP test3.03.14.71.3-1.21.01.7-1.81.91.9-1.7-1.9-1.91.9-2.00.3-1.6-2.1-2.22.2-2.1
Total zone transitions, NPP test0.81.22.80.4-0.90.50.9-1.01.21.2-1.1-1.2-1.21.2-0.90.3-1.7-1.3-1.31.1-1.3
Total locomotion distance, NPP test0.50.61.7-0.2-0.2-0.10.4-0.60.70.7-0.6-0.7-0.70.8-0.6-0.3-1.2-1.1-1.21.1-1.3
Locomotion velocity, NPP test0.20.31.1-0.50.1-0.40.0-0.30.40.4-0.2-0.4-0.40.5-0.2-0.5-1.0-0.8-0.90.8-1.1
Intraocular pressure0.71.03.1-0.5-0.00.2-0.70.7-0.8-0.80.51.01.0-0.81.11.10.11.41.6-1.81.6
Delta distance traveled before/after self-admin0.00.10.20.10.2-0.10.3-0.10.20.20.0-0.3-0.30.0-0.2-0.40.2-0.2-0.20.4-0.3
Delta ambulatory time before/after self-admin0.20.20.6-0.00.2-0.30.3-0.30.40.3-0.1-0.5-0.50.3-0.4-0.6-0.1-0.6-0.60.8-0.7
Parametrial fat weight0.10.20.4-0.20.3-0.2-0.40.4-0.4-0.40.40.40.4-0.50.4-0.00.50.60.6-0.50.6
Pavlov. Cond. lever latency0.20.30.90.6-0.40.50.20.0-0.2-0.20.10.10.1-0.30.20.70.50.70.8-0.81.0
Pavlov. Cond. magazine entry latency1.62.02.7-1.41.3-1.2-1.51.5-1.6-1.61.51.61.6-1.51.5-0.91.31.41.3-1.31.2
Pavlov. Cond. change in total contacts0.10.10.30.3-0.20.30.3-0.40.40.4-0.4-0.3-0.30.4-0.5-0.1-0.1-0.4-0.50.4-0.4
Pavlov. Cond. index score0.20.31.0-1.00.8-0.8-0.70.6-0.5-0.50.50.50.5-0.40.5-0.90.10.1-0.10.0-0.2
Pavlov. Cond. latency score0.30.41.4-1.10.9-1.0-0.80.6-0.4-0.40.60.50.5-0.30.4-1.20.1-0.1-0.30.3-0.5
Pavlov. Cond. lever contacts0.40.51.7-0.50.2-0.40.0-0.30.50.5-0.3-0.5-0.50.6-0.4-0.7-0.9-1.0-1.21.1-1.3
Pavlov. Cond. magazine entry number0.40.50.80.9-0.70.70.8-0.80.80.8-0.8-0.8-0.80.7-0.80.5-0.5-0.7-0.60.6-0.5
Pavlov. Cond. intertrial magazine entries0.30.30.90.0-0.00.1-0.30.4-0.6-0.60.30.60.6-0.50.40.40.60.80.9-0.90.9
Pavlov. Cond. lever-magazine prob. diff.0.40.51.2-1.10.9-1.0-0.90.7-0.6-0.60.70.70.7-0.50.6-1.00.30.20.0-0.1-0.1
Pavlov. Cond. response bias0.50.61.1-1.10.8-0.7-1.00.8-0.9-0.90.80.90.9-0.70.9-0.50.40.60.6-0.70.5
Pavlov. Cond. lever latency1.21.72.31.5-1.41.41.4-1.51.31.3-1.5-1.2-1.21.5-1.50.9-1.0-1.2-1.21.0-0.9
Pavlov. Cond. magazine entry latency2.12.43.3-1.81.8-1.8-1.81.8-1.5-1.51.81.51.5-1.71.7-1.41.41.31.2-1.00.9
Pavlov. Cond. change in total contacts0.91.21.8-1.01.2-1.1-1.11.2-1.1-1.11.31.01.0-1.31.1-0.91.31.01.0-0.80.8
Pavlov. Cond. index score2.02.63.5-1.71.7-1.7-1.71.8-1.6-1.61.91.61.6-1.81.7-1.31.71.51.4-1.21.1
Pavlov. Cond. latency score1.92.33.1-1.81.7-1.8-1.71.7-1.5-1.51.81.51.5-1.71.7-1.31.41.31.2-1.10.9
Pavlov. Cond. lever contacts1.31.82.4-1.31.3-1.2-1.41.5-1.4-1.41.51.31.3-1.51.5-0.81.31.41.4-1.21.1
Pavlov. Cond. magazine entry number2.02.53.41.7-1.81.81.8-1.81.61.6-1.8-1.6-1.61.7-1.61.5-1.6-1.3-1.21.0-0.9
Pavlov. Cond. intertrial magazine entries0.70.91.81.3-1.21.41.2-1.00.90.9-1.0-0.9-0.90.8-0.91.3-0.7-0.4-0.30.2-0.1
Pavlov. Cond. lever-magazine prob. diff.2.12.73.6-1.81.9-1.8-1.81.9-1.7-1.71.91.61.6-1.81.7-1.41.81.51.4-1.11.1
Pavlov. Cond. response bias2.33.13.9-1.71.8-1.6-1.81.9-1.9-1.82.01.81.8-2.01.9-1.11.81.81.8-1.51.5
Time in closed arm before self-admin0.70.81.9-0.1-0.2-0.10.4-0.71.01.0-0.7-0.9-0.90.9-0.8-0.2-1.3-1.2-1.11.2-1.4
Time in closed arm after self-admin0.10.10.20.40.10.20.5-0.20.20.2-0.1-0.2-0.20.0-0.5-0.10.5-0.2-0.20.5-0.1
Time in open arm before self-admin1.51.65.3-0.21.2-0.8-0.81.2-1.5-1.41.41.41.4-1.60.9-1.52.31.20.8-0.71.1
Time in open arm after self-admin1.01.22.01.3-1.41.31.2-1.21.11.1-1.3-1.1-1.11.2-1.01.0-1.0-0.7-0.70.4-0.4
Bone: periosteal estimation1.22.56.30.8-0.30.31.2-1.31.51.5-1.2-1.6-1.61.6-1.9-1.0-0.7-2.1-2.42.5-2.2
Bone: periosteal perimeter0.40.72.9-0.30.8-0.9-0.1-0.00.30.30.1-0.3-0.30.3-0.6-1.70.4-0.9-1.31.5-1.4
Bone: post-yield work0.30.40.70.8-0.60.50.7-0.60.60.6-0.6-0.6-0.60.6-0.70.2-0.2-0.6-0.60.7-0.5
Progressive ratio test 1 active lever presses0.91.02.41.2-0.70.91.5-1.11.11.1-0.9-1.2-1.20.9-1.20.3-0.1-0.8-0.70.9-0.6
Progressive ratio test 1 breakpoint1.11.12.61.2-0.80.91.6-1.11.21.2-1.0-1.3-1.31.0-1.30.3-0.2-0.9-0.91.1-0.8
Progressive ratio test 1 inactive lever presses0.70.84.8-0.01.2-0.80.00.7-0.8-0.80.90.60.6-0.90.1-1.72.20.4-0.00.40.2
Progressive ratio test 2 active lever presses0.30.30.80.7-0.00.30.9-0.40.50.5-0.3-0.6-0.60.3-0.8-0.50.5-0.5-0.70.8-0.5
Progressive ratio test 2 breakpoint0.30.31.50.20.5-0.30.5-0.10.20.20.1-0.4-0.40.1-0.5-1.20.8-0.5-0.81.0-0.7
Progressive ratio test 2 inactive lever presses0.30.31.40.40.5-0.20.8-0.10.20.20.1-0.4-0.40.0-0.6-1.21.0-0.4-0.71.0-0.6
Incentive Sensitization - Responses0.30.31.3-0.30.8-0.5-0.30.6-0.6-0.60.70.60.6-0.60.4-0.91.10.40.2-0.00.2
Incentive Sensitization - Breakpoint0.40.41.4-0.40.9-0.7-0.50.7-0.7-0.70.80.70.7-0.70.4-1.11.20.30.10.10.1
Sum of active levers in priming session hrs 5-60.30.30.5-0.60.4-0.5-0.50.6-0.6-0.60.50.60.6-0.60.60.10.50.60.7-0.60.5
Progressive ratio0.70.82.21.5-0.91.11.2-1.00.90.9-0.9-0.9-0.90.8-1.10.4-0.2-0.7-0.80.6-0.4
Food seeking constrained by brief footshock1.01.22.4-1.50.7-1.0-1.51.2-1.1-1.11.01.21.2-1.01.4-0.0-0.01.01.2-1.30.9
Seeking ratio, punishment vs. effort1.51.83.7-1.91.1-1.3-1.81.5-1.4-1.41.31.51.5-1.21.7-0.10.31.21.5-1.41.0
Retroperitoneal fat weight2.06.49.53.1-2.93.03.0-2.82.72.7-2.8-2.7-2.72.6-2.82.2-2.0-2.0-1.71.6-1.3
Reaction time number correct0.81.24.01.4-1.71.71.1-1.20.90.9-1.2-0.8-0.81.0-0.82.0-1.0-0.4-0.1-0.10.1
Reaction time mean minus median1.01.42.2-1.51.4-1.3-1.41.3-1.2-1.21.31.21.2-1.21.3-1.00.91.01.0-0.70.6
Reaction time mean minus median AUC0.81.13.5-1.91.6-1.7-1.21.0-0.7-0.71.10.70.7-0.70.9-1.80.20.1-0.10.3-0.5
Reaction time num false alarms0.50.61.31.2-0.91.11.0-0.90.90.9-0.8-0.9-0.90.7-0.80.6-0.6-0.5-0.50.4-0.3
Reaction time num false alarms AUC0.50.71.81.3-1.01.41.1-1.00.80.8-0.8-0.9-0.90.7-0.70.8-0.5-0.4-0.30.2-0.1
Reaction time trials correct on left0.81.24.01.4-1.71.71.1-1.20.90.9-1.2-0.8-0.81.0-0.82.0-1.0-0.4-0.1-0.10.1
Reaction time trials on left0.81.23.71.4-1.61.61.1-1.20.90.9-1.2-0.9-0.91.0-0.81.9-1.0-0.4-0.1-0.10.1
Reaction time mean0.60.82.8-1.71.3-1.4-1.21.0-0.7-0.71.00.70.7-0.70.9-1.20.20.30.3-0.1-0.2
Reaction time mean AUC0.30.41.5-1.20.9-1.0-0.80.6-0.3-0.30.50.30.3-0.30.5-1.0-0.0-0.1-0.00.2-0.4
Median of all reaction times0.30.41.5-1.20.8-1.1-0.80.6-0.4-0.40.50.30.3-0.30.5-0.8-0.1-0.00.00.1-0.4
Reaction time omissions0.10.10.6-0.20.4-0.3-0.00.0-0.1-0.10.2-0.0-0.0-0.0-0.1-0.80.3-0.2-0.30.5-0.3
Reaction time false alarm rate0.10.20.40.5-0.20.40.5-0.50.50.5-0.3-0.6-0.60.3-0.4-0.2-0.3-0.4-0.50.4-0.4
Reaction time premature initiation rate1.82.43.6-1.00.8-1.0-1.41.5-1.7-1.71.41.81.8-1.71.70.11.41.81.8-1.91.8
Reaction time premature initiations1.11.64.0-0.2-0.1-0.0-0.81.0-1.3-1.30.81.41.4-1.21.31.10.91.71.9-2.01.9
Std. dev. reaction times0.50.71.8-1.31.3-1.2-1.00.9-0.7-0.71.00.60.6-0.80.9-1.30.50.40.3-0.10.0
Reaction time trials completed0.81.23.71.4-1.61.61.1-1.20.90.9-1.2-0.9-0.91.0-0.81.9-1.0-0.4-0.1-0.10.1
Reaction time trials AUC0.91.34.61.5-1.81.81.1-1.20.90.9-1.3-0.9-0.91.0-0.82.1-1.0-0.3-0.0-0.20.2
Run reversals in cocaine runway, females1.31.22.8-1.51.3-1.7-1.41.3-1.0-1.01.21.11.1-1.01.2-1.30.80.70.5-0.50.3
Run reversals in cocaine runway, males2.22.24.0-1.91.8-2.0-1.71.6-1.6-1.61.61.51.5-1.41.4-1.61.31.00.9-0.50.6
Latency to leave start box in cocaine runway0.90.92.7-0.20.2-0.00.5-0.71.01.0-0.5-1.0-1.00.8-0.8-0.8-1.1-1.3-1.51.5-1.6
Latency to leave start box in cocaine runway, F1.61.85.0-0.30.0-0.20.6-0.91.31.3-0.8-1.3-1.31.3-1.1-1.0-1.7-1.9-2.02.0-2.2
Latency to leave start box in cocaine runway, M0.20.20.50.5-0.10.50.10.1-0.2-0.20.20.10.1-0.40.20.50.70.50.5-0.60.7
Std. dev. time between licks in bursts0.70.93.7-1.01.3-1.3-0.90.9-0.9-0.80.90.80.8-0.60.5-1.91.1-0.0-0.30.7-0.5
Total sessions with >9 infusions0.91.05.1-0.01.0-0.80.7-0.10.30.30.2-0.4-0.40.2-0.9-2.31.1-0.9-1.41.8-1.3
Short access day 1 total inactive lever presses0.20.21.1-0.00.6-0.4-0.00.3-0.3-0.30.40.30.3-0.4-0.0-0.81.00.2-0.00.30.1
Short access day 10 total inactive lever presses0.60.63.00.40.40.0-0.10.6-0.9-0.90.70.80.8-0.90.4-0.21.70.90.8-0.61.1
Short access day 1 total infusions1.11.24.60.30.6-0.51.2-0.50.60.7-0.3-0.7-0.70.6-1.4-1.90.8-1.3-1.62.2-1.6
Short access day 10 total infusions0.50.51.20.8-0.10.31.1-0.60.70.7-0.4-0.9-0.90.5-1.0-0.50.5-0.7-0.81.1-0.7
Short access total infusions1.51.74.70.9-0.10.21.7-1.11.21.2-0.9-1.4-1.41.1-1.7-1.10.1-1.5-1.82.2-1.7
Short access day 1 locomotion0.40.52.8-0.41.1-1.0-0.10.5-0.2-0.20.70.10.1-0.50.1-1.71.3-0.1-0.30.6-0.4
Short access day 10 total locomotion3.64.010.2-1.02.0-1.5-1.52.2-2.3-2.32.22.12.1-2.41.8-1.53.22.01.7-1.41.7
Short access total locomotion0.60.62.4-0.51.1-1.0-0.20.8-0.7-0.70.90.50.5-0.90.4-1.41.50.40.20.10.1
One hour access (0.3 mA shock)0.30.30.70.7-0.40.60.8-0.60.50.6-0.6-0.8-0.80.5-0.70.2-0.2-0.5-0.60.5-0.3
Compulsive drug intake0.50.51.20.4-0.70.60.5-0.70.80.8-0.8-0.8-0.80.7-0.60.5-1.1-0.5-0.50.3-0.4
One hour access (shock baseline)0.20.21.60.50.20.20.40.2-0.4-0.40.30.20.2-0.40.0-0.21.30.40.3-0.10.4
Social response proportion0.40.41.3-1.10.5-0.9-1.00.7-0.6-0.60.50.70.7-0.40.8-0.4-0.30.20.2-0.3-0.0
Social responses6.48.213.6-3.73.3-3.5-3.53.3-2.9-2.93.23.13.1-2.93.2-2.81.92.11.8-1.61.2
Social time1.11.52.61.4-1.61.41.2-1.41.21.2-1.5-1.2-1.21.4-1.31.4-1.3-1.0-0.80.6-0.6
Soleus weight6.117.922.54.5-4.64.54.6-4.74.64.6-4.7-4.5-4.54.6-4.43.5-4.0-3.8-3.33.0-2.8
Bone: stiffness4.47.09.22.6-2.22.12.8-2.82.92.9-2.7-3.0-3.02.9-3.00.8-2.1-2.8-2.82.8-2.4
Tibialis anterior weight1.34.65.62.2-2.32.22.3-2.42.32.4-2.3-2.3-2.32.3-2.21.8-2.1-2.0-1.61.6-1.5
Time to tail flick, vehicle, before self-admin1.92.05.1-1.92.1-2.1-1.41.5-1.2-1.31.51.31.3-1.20.8-2.21.50.30.00.5-0.4
Time to tail flick, vehicle, after self-admin0.50.51.3-0.10.10.0-0.70.6-0.7-0.60.50.90.9-0.80.80.30.51.01.0-1.11.1
Time to tail flick, test, before self-admin0.90.94.2-1.21.3-1.5-1.10.9-0.5-0.50.90.60.6-0.80.5-2.00.6-0.0-0.30.4-0.5
Time to tail flick, test, after self-admin0.20.31.2-0.60.7-0.8-0.20.10.10.00.3-0.1-0.1-0.1-0.1-1.10.0-0.5-0.60.8-0.8
Delta time to tail flick, vehicle, before/after SA1.71.75.81.5-2.12.00.9-1.21.01.1-1.4-0.9-0.91.0-0.52.4-1.7-0.10.3-0.80.6
Delta time to tail flick, test, before/after SA0.30.31.2-0.1-0.30.3-0.10.1-0.4-0.40.10.40.4-0.20.51.1-0.20.60.9-0.90.8
Tibia length0.82.23.6-1.61.1-1.3-1.71.6-1.7-1.61.61.51.5-1.61.9-0.50.91.61.6-1.61.3
Ambulatory time before self-admin0.20.20.4-0.60.5-0.4-0.50.6-0.6-0.60.50.70.7-0.40.5-0.10.30.40.4-0.40.3
Ambulatory time after self-admin0.00.00.2-0.30.5-0.30.00.2-0.2-0.20.30.00.0-0.10.2-0.30.30.1-0.00.1-0.1
Bone: tissue strength3.93.85.12.0-1.71.72.2-2.12.12.1-2.0-2.1-2.12.1-2.30.8-1.5-2.0-2.02.0-1.7
Total heroin consumption1.61.93.5-1.91.5-1.6-1.71.6-1.5-1.51.51.51.5-1.41.6-1.00.81.01.0-0.90.6
Bone: trabecular number0.50.83.4-1.31.3-1.6-0.80.7-0.2-0.20.80.10.1-0.40.5-1.80.1-0.4-0.60.7-1.0
Bone: trabecular spacing0.91.23.91.1-0.91.40.30.0-0.5-0.5-0.10.50.5-0.40.32.00.71.31.6-1.72.0
Bone: trabecular thickness2.42.99.3-0.70.8-1.30.3-0.61.21.2-0.5-1.3-1.31.1-1.3-2.6-0.9-2.3-2.93.0-3.1
Bone: trabecular tissue density4.25.99.73.1-2.83.03.0-2.72.62.6-2.7-2.6-2.62.4-2.72.3-1.7-1.7-1.51.4-0.9
Water consumed over 24 hours1.11.32.60.7-0.50.31.1-1.01.11.1-1.0-1.3-1.31.1-1.3-0.2-0.8-1.5-1.61.6-1.6
Number of responses in last shaping day2.22.36.5-1.02.0-1.5-0.91.6-1.7-1.71.71.61.6-1.71.1-2.02.51.20.9-0.40.8