Hub : Genes

Birc5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_063269805.1 0.23 0.11 0.0e+00 0.21 0.22 0.2 0.21 4.4e-23 3.7e-24 3.2e-22 5.1e-23
2 Liver alternative TSS NM_022274.2 0.24 0.11 0.0e+00 0.21 0.22 0.2 0.21 6.1e-23 3.9e-24 5.2e-22 5.8e-23
3 Liver gene expression Birc5 0.41 0.13 0.0e+00 0.36 0.37 0.36 0.36 4.7e-41 8.9e-43 3.5e-41 1.6e-41
4 BLA gene expression Birc5 0.12 0.07 1.6e-05 0.08 0.1 0.1 0.09 3.5e-05 3.4e-06 7.3e-06 1.3e-05
5 pVTA isoform ratio NM_022274.2 0.06 0.04 3.7e-06 0.04 0.06 0.04 0.05 1.6e-04 6.7e-06 1.8e-04 1.3e-04
6 pVTA isoform ratio XM_063269805.1 0.06 0.04 7.3e-06 0.04 0.06 0.04 0.04 2.9e-04 1.5e-05 4.5e-04 3.1e-04
7 PL gene expression Birc5 0.09 0.05 3.4e-14 0.11 0.12 0.1 0.12 2.7e-12 6.5e-13 1.4e-11 6.4e-13
8 IL gene expression Birc5 0.15 0.12 3.6e-03 0.07 0.06 0.01 0.05 8.9e-03 1.3e-02 1.5e-01 2.3e-02
9 Liver isoform ratio NM_022274.2 0.08 0.07 7.7e-04 0.02 0.02 0.02 0.02 1.3e-03 4.0e-03 6.5e-03 1.6e-03
10 Liver isoform ratio XM_063269805.1 0.09 0.07 7.9e-04 0.02 0.02 0.01 0.02 1.6e-03 4.2e-03 9.0e-03 3.4e-03
11 PL isoform ratio NM_022274.2 0.03 0.02 7.6e-04 0.03 0.02 0.03 0.03 5.2e-04 2.2e-03 8.6e-04 6.5e-04
12 PL isoform ratio XM_063269805.1 0.03 0.02 7.1e-04 0.03 0.02 0.02 0.03 4.7e-04 1.9e-03 1.2e-03 8.9e-04
13 Adipose alternative TSS XM_063269805.1 0.04 0.03 3.3e-04 0.02 0.03 0.03 0.03 2.0e-03 5.8e-04 8.1e-04 2.2e-04
14 IC gene expression Birc5 0.09 0.06 3.7e-04 0.07 0.08 0.06 0.07 1.0e-03 3.6e-04 1.4e-03 9.7e-04
15 Brain gene expression Birc5 0.1 0.06 1.6e-06 0.06 0.06 0.06 0.06 1.3e-06 2.8e-06 5.3e-06 2.8e-06
16 Liver intron excision ratio chr10_103577291_103579528 0.03 0.02 1.4e-03 0.01 0.02 0.01 0.01 6.4e-02 4.5e-03 8.4e-03 2.5e-02
17 Liver intron excision ratio chr10_103576539_103579528 0.03 0.02 9.3e-04 0.01 0.02 0.01 0.01 5.6e-02 3.7e-03 7.0e-03 2.0e-02
18 Adipose isoform ratio XM_063269805.1 0.04 0.03 1.2e-05 0.04 0.03 0.03 0.03 3.7e-05 2.0e-04 3.2e-04 1.2e-04
19 Eye isoform ratio XM_063269805.1 0.2 0.14 8.1e-03 0.1 0.14 0.13 0.1 1.2e-02 4.2e-03 5.0e-03 1.4e-02
20 NAcc gene expression Birc5 0.07 0.04 4.9e-07 0.04 0.05 0.05 0.04 5.0e-07 8.9e-08 1.4e-07 2.2e-07
21 NAcc isoform ratio NM_022274.2 0.07 0.05 2.0e-06 0.03 0.04 0.03 0.03 6.7e-06 3.9e-06 1.6e-05 8.9e-06
22 NAcc isoform ratio XM_063269805.1 0.09 0.06 9.2e-07 0.04 0.04 0.04 0.04 2.0e-06 1.0e-06 2.8e-06 3.2e-06
23 OFC gene expression Birc5 0.27 0.18 9.8e-04 0.04 0.07 0.08 0.06 3.6e-02 9.7e-03 4.9e-03 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.61.12.80.7-0.7-0.8-1.21.5-1.5-1.0-0.5-0.50.50.5-0.5-0.7-1.4-0.8-1.71.7-1.5-1.3-0.51.1-1.1-0.3
Area under the delay curve0.60.74.5-0.80.80.70.3-1.01.00.70.40.4-0.4-0.40.40.61.20.61.0-1.11.11.30.3-0.20.12.1
BMI with tail0.51.66.0-0.90.91.12.1-0.70.71.00.80.8-0.8-0.80.80.80.41.20.7-0.61.10.11.8-2.32.5-2.4
BMI without tail0.41.23.31.1-1.1-1.0-0.30.9-0.9-1.0-1.5-1.51.51.5-1.5-1.3-1.1-1.0-0.80.8-0.6-1.3-0.60.10.1-1.8
Body weight0.83.68.2-1.81.82.02.7-1.91.91.91.41.4-1.4-1.41.41.51.62.01.9-1.92.31.42.3-2.82.9-0.8
Weight adjusted by age0.00.00.3-0.30.30.3-0.10.1-0.10.10.10.1-0.1-0.10.10.10.00.3-0.20.2-0.10.10.30.0-0.00.5
Bone surface0.71.25.4-1.51.51.20.2-0.60.61.01.31.3-1.3-1.31.31.20.81.10.3-0.30.81.11.1-0.20.12.3
Bone volume0.20.42.1-0.80.80.6-0.20.2-0.20.40.80.8-0.8-0.80.80.6-0.00.5-0.40.40.10.20.70.2-0.21.4
Breakpoint value in progressive ratio session0.50.62.1-1.21.21.10.7-0.10.00.80.80.8-0.8-0.80.80.70.21.1-0.20.20.80.21.5-1.01.10.3
Number of licking bursts0.00.00.1-0.10.00.10.1-0.20.20.1-0.1-0.10.10.1-0.1-0.00.2-0.00.3-0.30.30.20.0-0.10.10.2
Context. condit. distance diff. score0.30.40.7-0.80.80.80.5-0.50.50.70.70.7-0.7-0.70.70.70.50.60.4-0.40.80.60.8-0.50.50.4
Locomotion velocity, session 10.30.31.2-0.20.20.30.3-0.91.00.40.20.2-0.2-0.20.20.40.90.21.1-1.10.40.9-0.2-0.0-0.10.8
Locomotion distance, session 12.83.64.42.1-2.1-2.0-1.71.8-1.8-1.9-2.0-2.02.02.0-2.0-2.0-1.9-1.9-1.81.8-1.9-2.0-1.81.6-1.5-1.6
Locomotion velocity, session 20.60.71.10.9-0.9-0.8-0.80.8-0.8-0.7-0.7-0.70.70.7-0.7-0.8-0.9-0.8-0.80.8-1.0-0.9-0.80.8-0.8-0.4
Locomotion distance, session 26.08.312.33.1-3.1-3.0-2.63.0-3.0-3.0-2.8-2.82.82.8-2.8-3.0-3.1-2.8-2.92.9-3.5-3.1-2.62.6-2.4-2.4
Locomotion velocity, session 30.20.30.70.4-0.4-0.4-0.4-0.30.3-0.2-0.6-0.60.60.6-0.6-0.40.3-0.50.5-0.50.10.4-0.80.6-0.70.8
Locomotion distance, session 30.30.31.70.7-0.7-0.6-0.00.3-0.3-0.4-0.6-0.60.60.6-0.6-0.5-0.4-0.6-0.20.2-0.1-0.6-0.4-0.10.2-1.3
Stereotopy head waving bouts, day 32.63.03.9-2.02.02.01.8-1.61.61.91.81.8-1.8-1.81.81.81.72.01.5-1.51.51.61.9-1.61.60.9
Stereotopy head waving duration, day 32.32.74.0-2.02.01.91.5-1.51.51.71.81.8-1.8-1.81.81.71.62.01.4-1.41.31.61.8-1.41.31.4
Locomotion velocity, session 70.20.20.60.4-0.4-0.5-0.70.3-0.3-0.4-0.5-0.50.50.5-0.5-0.4-0.2-0.6-0.30.3-0.3-0.1-0.70.8-0.80.6
Locomotion distance, session 72.83.65.21.8-1.8-1.8-2.02.2-2.2-1.9-1.8-1.81.81.8-1.8-1.9-2.2-1.9-2.32.3-1.9-2.1-1.61.7-1.6-1.1
Stereotopy head waving bouts, day 74.95.56.5-2.52.52.52.2-2.42.42.52.32.3-2.3-2.32.32.42.52.42.4-2.32.52.52.3-2.12.01.7
Stereotopy head waving duration, day 76.17.38.9-2.92.92.92.4-2.82.82.82.72.7-2.7-2.72.72.82.92.92.7-2.72.63.02.5-2.12.02.4
Locomotion velocity, session 80.30.42.2-0.70.70.60.1-0.70.70.60.50.5-0.5-0.50.50.50.80.50.6-0.60.41.00.30.2-0.31.5
Locomotion distance, session 82.23.34.71.7-1.7-1.7-1.72.1-2.1-1.7-1.6-1.61.61.6-1.6-1.8-2.1-1.8-2.22.2-2.0-2.1-1.41.5-1.4-1.5
Degree of sensitization distance3.43.55.31.5-1.5-1.7-2.32.2-2.2-1.9-1.7-1.71.71.7-1.7-1.8-2.0-1.8-2.32.3-2.0-1.7-1.62.2-2.20.2
Degree of sensitization stereotypy1.71.92.8-1.51.51.41.4-1.51.51.41.21.2-1.2-1.21.21.41.51.31.5-1.41.71.51.3-1.31.30.9
Conditioned locomotion0.40.51.20.4-0.4-0.5-0.60.6-0.6-0.7-1.1-1.11.11.1-1.1-0.9-0.6-0.6-0.70.7-0.5-0.6-0.40.5-0.4-0.0
Cocaine response after cond. corrected0.30.40.7-0.70.70.70.8-0.50.50.60.60.6-0.6-0.60.60.70.50.70.5-0.40.50.40.8-0.80.8-0.0
Cocaine response after cond. not corrected0.10.10.2-0.30.30.30.2-0.30.30.20.40.4-0.4-0.40.40.40.30.30.2-0.20.10.30.2-0.10.10.4
Cocaine response before conditioning0.50.62.20.7-0.7-0.8-1.20.5-0.5-0.7-0.4-0.40.40.4-0.4-0.5-0.3-0.8-0.40.4-0.7-0.1-1.21.4-1.51.0
Saline control response1.41.94.91.4-1.5-1.5-1.80.5-0.4-1.3-1.5-1.51.51.5-1.5-1.3-0.3-1.5-0.20.2-0.9-0.2-2.22.1-2.21.1
Bone: connectivity density1.21.93.61.2-1.2-1.3-1.81.6-1.6-1.5-1.1-1.11.11.1-1.1-1.2-1.4-1.2-1.71.7-1.8-1.2-1.31.9-1.90.0
Bone: cortical apparent density1.01.45.91.2-1.2-1.0-0.51.3-1.3-1.1-0.8-0.80.80.8-0.8-1.0-1.5-0.7-1.41.4-1.7-1.6-0.50.5-0.4-2.4
Bone: cortical area4.56.910.0-2.52.52.73.2-2.62.62.82.82.8-2.8-2.82.82.72.32.72.5-2.52.42.12.8-3.03.0-0.2
Bone: cortical porosity2.02.22.7-1.51.51.51.2-1.51.51.51.71.7-1.7-1.71.71.61.61.61.4-1.41.11.61.3-0.90.81.4
Bone: cortical porosity3.03.24.1-1.91.91.91.5-1.91.91.81.91.9-1.9-1.91.91.91.92.01.8-1.81.62.01.6-1.21.11.9
Bone: cortical thickness1.01.711.0-0.20.20.62.1-1.31.20.90.90.9-0.9-0.90.90.80.70.91.4-1.40.60.21.0-2.02.0-3.3
Bone: cortical thickness0.40.53.60.1-0.10.21.2-0.60.60.30.30.3-0.3-0.30.30.40.30.40.7-0.70.5-0.00.4-1.21.2-1.9
Bone: cortical tissue density1.01.45.51.2-1.2-1.0-0.51.3-1.4-1.1-0.8-0.80.80.8-0.8-1.1-1.6-0.8-1.41.4-1.7-1.7-0.50.5-0.4-2.4
Condit. Reinf. active minus inactive responses0.20.20.50.4-0.4-0.5-0.70.4-0.4-0.5-0.5-0.50.50.5-0.5-0.5-0.3-0.5-0.40.4-0.4-0.3-0.60.7-0.70.4
Condit. Reinf. active-inactive response ratio0.20.20.70.1-0.1-0.2-0.70.5-0.5-0.40.10.1-0.1-0.10.1-0.1-0.4-0.1-0.70.7-0.8-0.2-0.20.8-0.90.8
Condit. Reinf. active responses1.01.32.01.2-1.2-1.3-1.30.9-0.9-1.2-1.3-1.31.31.3-1.3-1.2-0.8-1.4-0.80.8-0.9-0.8-1.41.3-1.30.1
Condit. Reinf. inactive responses1.31.62.81.5-1.5-1.5-1.20.9-0.9-1.2-1.6-1.61.61.6-1.6-1.4-0.9-1.7-0.70.7-0.8-1.0-1.51.0-1.0-0.6
Incentive salience index mean0.10.10.50.3-0.3-0.3-0.50.2-0.2-0.4-0.3-0.30.30.3-0.3-0.3-0.1-0.5-0.10.1-0.2-0.0-0.50.6-0.60.7
Condit. Reinf. lever presses0.30.40.80.7-0.7-0.7-0.70.5-0.5-0.7-0.8-0.80.80.8-0.8-0.7-0.4-0.9-0.40.4-0.4-0.4-0.80.6-0.60.2
Condit. Reinf. active minus inactive responses0.10.21.1-0.20.20.1-0.1-0.40.40.20.40.4-0.4-0.40.40.40.50.10.4-0.40.10.6-0.20.3-0.31.0
Condit. Reinf. active-inactive response ratio0.10.10.5-0.00.00.0-0.1-0.30.30.0-0.0-0.00.00.0-0.00.10.4-0.00.4-0.40.10.5-0.20.2-0.30.7
Condit. Reinf. active responses0.10.20.40.3-0.3-0.4-0.60.6-0.6-0.4-0.1-0.10.10.1-0.1-0.2-0.5-0.3-0.60.6-0.7-0.4-0.40.6-0.60.3
Condit. Reinf. inactive responses0.70.91.60.9-0.9-0.9-1.11.2-1.2-1.0-0.7-0.70.70.7-0.7-0.8-1.1-0.8-1.31.3-1.2-1.1-0.81.1-1.0-0.2
Condit. Reinf. lever presses1.01.42.31.0-1.0-1.1-1.41.4-1.4-1.2-1.1-1.11.11.1-1.1-1.2-1.3-1.0-1.51.5-1.5-1.2-1.01.4-1.3-0.1
Condit. Reinf. lever reinforcers received0.20.20.80.3-0.3-0.3-0.50.8-0.8-0.4-0.1-0.10.10.1-0.1-0.2-0.7-0.3-0.90.9-0.7-0.6-0.10.4-0.4-0.2
Conditioned reinforcement - actives0.30.53.10.5-0.5-0.4-0.00.8-0.8-0.4-0.4-0.40.40.4-0.4-0.4-1.0-0.5-0.90.9-0.4-1.10.1-0.30.4-1.8
Conditioned reinforcement - inactives0.10.10.70.0-0.00.10.4-0.30.30.20.20.2-0.2-0.20.20.10.10.10.3-0.30.00.00.1-0.30.3-0.8
Conditioned locomotion0.70.93.60.8-0.8-0.8-0.41.3-1.3-0.8-0.6-0.60.60.6-0.6-0.7-1.4-0.8-1.31.3-0.9-1.5-0.20.10.0-1.9
Patch foraging indifference point 0 sec0.91.72.61.2-1.2-1.3-1.41.6-1.6-1.2-1.3-1.31.31.3-1.3-1.3-1.6-1.4-1.61.6-1.2-1.5-1.11.1-1.0-0.6
Patch foraging indifference point AUC1.92.74.51.7-1.7-1.8-2.11.3-1.3-1.6-1.8-1.81.81.8-1.8-1.7-1.2-1.9-1.21.2-1.4-1.0-2.12.1-2.10.2
Delay disc. indifference point, 0s delay0.50.51.5-0.50.50.50.3-1.11.10.50.50.5-0.5-0.50.50.61.10.51.2-1.20.61.2-0.00.0-0.21.2
Delay disc. indifference point, 16s delay0.20.30.40.4-0.4-0.4-0.60.5-0.5-0.5-0.6-0.60.60.6-0.6-0.6-0.4-0.5-0.50.5-0.2-0.4-0.40.5-0.50.3
Delay disc. indifference point, 2s delay0.20.21.9-0.40.40.30.1-0.50.50.20.10.1-0.1-0.10.10.30.60.30.6-0.60.80.70.1-0.10.01.4
Delay disc. indifference point, 24s delay0.10.10.30.2-0.2-0.2-0.30.1-0.1-0.2-0.2-0.20.20.2-0.2-0.2-0.0-0.1-0.10.1-0.40.0-0.30.4-0.40.5
Delay disc. indifference point, 4s delay0.80.84.0-0.80.80.70.3-1.11.10.70.60.6-0.6-0.60.60.81.30.71.2-1.21.11.30.2-0.10.02.0
Delay disc. indifference point, 8s delay2.83.28.0-1.81.81.71.2-2.12.11.81.41.4-1.4-1.41.41.62.31.62.2-2.22.12.41.1-1.00.82.8
Indifference point function ln k0.40.72.8-0.50.60.71.3-0.20.20.60.80.8-0.8-0.80.80.7-0.10.80.1-0.10.2-0.31.3-1.51.6-1.7
Indifference point function log k0.40.72.8-0.50.60.71.3-0.20.20.60.80.8-0.8-0.80.80.7-0.10.80.1-0.10.2-0.31.3-1.51.6-1.7
Patch foraging total patch changes 0 sec1.12.23.31.4-1.4-1.5-1.51.8-1.8-1.3-1.4-1.41.41.4-1.4-1.4-1.8-1.5-1.81.8-1.4-1.7-1.21.2-1.1-0.8
Patch foraging total patch changes 12 sec4.76.07.82.6-2.6-2.6-2.62.4-2.4-2.4-2.7-2.72.72.7-2.7-2.6-2.3-2.8-2.32.2-2.0-2.3-2.62.3-2.3-1.2
Patch foraging total patch changes 18 sec2.74.15.91.8-1.8-2.0-2.42.2-2.1-1.9-2.3-2.32.32.3-2.3-2.0-1.9-2.2-2.12.1-1.5-1.7-2.02.2-2.10.2
Patch foraging total patch changes 24 sec0.10.22.1-0.00.0-0.1-0.6-0.10.10.2-0.0-0.00.00.0-0.00.00.3-0.40.1-0.20.20.4-0.50.6-0.71.4
Patch foraging total patch changes 6 sec2.13.23.91.9-1.9-1.9-1.81.8-1.8-1.7-1.8-1.81.81.8-1.8-2.0-1.8-1.8-1.81.8-1.7-1.8-1.71.7-1.7-1.1
Patch foraging time to switch 0 sec0.20.40.5-0.70.70.70.6-0.60.60.50.50.5-0.5-0.50.50.50.70.70.6-0.60.70.70.6-0.50.50.6
Patch foraging water rate 0 sec0.71.42.31.3-1.3-1.3-1.31.3-1.3-1.1-1.2-1.21.21.2-1.2-1.2-1.2-1.5-1.21.2-0.9-1.2-1.31.1-1.1-0.3
Patch foraging water rate 12 sec0.20.44.70.3-0.3-0.20.40.6-0.6-0.10.10.1-0.1-0.10.1-0.2-0.8-0.3-0.60.7-0.4-1.00.4-0.60.7-2.2
Patch foraging water rate 18 sec0.10.20.70.2-0.2-0.2-0.20.7-0.7-0.3-0.3-0.30.30.3-0.3-0.5-0.7-0.3-0.80.8-0.5-0.80.10.00.0-0.6
Patch foraging water rate 24 sec1.42.03.11.2-1.2-1.3-1.31.7-1.7-1.3-1.5-1.51.51.5-1.5-1.5-1.7-1.5-1.81.8-1.2-1.6-0.91.0-0.9-0.8
Patch foraging water rate 6 sec0.10.22.10.4-0.4-0.30.20.3-0.3-0.1-0.2-0.20.20.2-0.2-0.1-0.5-0.3-0.20.2-0.3-0.6-0.0-0.30.4-1.5
Seeking ratio, delayed vs. immediate footshock0.10.20.60.5-0.5-0.5-0.60.2-0.1-0.4-0.1-0.10.10.1-0.1-0.1-0.1-0.6-0.10.1-0.4-0.1-0.80.7-0.80.1
Distance traveled before self-admin0.20.20.7-0.30.20.20.3-0.70.70.40.30.3-0.3-0.30.30.40.70.10.8-0.80.60.7-0.0-0.20.10.4
Distance traveled after self-admin1.01.32.70.8-0.8-0.9-1.21.5-1.5-1.1-1.0-1.01.01.0-1.0-1.1-1.4-1.1-1.61.6-1.2-1.3-0.61.0-0.9-0.5
Extensor digitorum longus weight1.24.76.42.2-2.2-2.1-1.52.2-2.2-2.3-2.5-2.52.52.5-2.5-2.4-2.4-2.2-2.22.2-1.7-2.5-1.61.1-1.0-2.3
Bone: elastic displacement1.21.35.61.4-1.4-1.2-0.51.0-1.0-1.1-1.0-1.01.01.0-1.0-1.1-1.3-0.9-1.01.0-1.4-1.4-0.90.5-0.4-2.4
Bone: elastic work0.81.12.5-0.70.70.91.6-0.90.80.91.01.0-1.0-1.01.00.90.61.20.8-0.80.50.41.2-1.51.5-1.6
Bone: endosteal estimation1.53.310.4-2.62.62.21.0-0.90.91.92.02.0-2.0-2.02.02.01.31.80.6-0.61.81.62.2-1.21.23.2
Bone: endosteal perimeter5.411.522.2-4.24.23.82.4-2.82.83.53.63.6-3.6-3.63.63.63.23.62.5-2.53.33.53.5-2.32.24.7
Epididymis fat weight0.10.41.7-0.60.60.60.9-0.00.00.40.30.3-0.3-0.30.30.3-0.10.6-0.10.10.6-0.21.1-1.21.3-1.1
Delta time in closed arm before/after self-admin0.20.21.60.1-0.1-0.3-0.70.3-0.3-0.3-0.4-0.40.40.4-0.4-0.4-0.1-0.4-0.30.3-0.10.0-0.50.7-0.71.3
Delta time in open arm before/after self-admin1.00.91.31.1-1.1-1.1-0.90.9-0.9-1.0-1.0-1.01.01.0-1.0-1.1-0.9-1.1-0.80.8-0.8-1.0-1.00.9-0.9-0.6
Diff in mean of infusions in LGA sessions1.31.63.2-1.81.81.61.0-0.70.71.41.31.3-1.3-1.31.31.30.91.60.5-0.41.31.01.7-1.11.11.6
Delay discount exponential model param0.91.05.11.0-1.0-0.9-0.41.1-1.2-0.9-0.6-0.60.60.6-0.6-0.8-1.3-0.8-1.21.2-1.3-1.4-0.50.3-0.2-2.2
Extinction: sum of active levers before priming0.10.10.6-0.10.10.20.30.3-0.3-0.0-0.1-0.10.10.1-0.1-0.1-0.30.1-0.40.4-0.1-0.40.5-0.40.5-0.7
Active lever presses in extinction session 60.10.11.1-0.10.10.10.20.3-0.3-0.0-0.2-0.20.20.2-0.2-0.2-0.30.3-0.40.4-0.2-0.40.4-0.40.5-1.1
Bone: final force1.82.94.1-1.61.61.82.0-1.71.71.81.91.9-1.9-1.91.91.81.51.91.6-1.61.31.41.8-1.81.7-0.1
Bone: final moment2.13.34.6-1.81.81.92.1-1.81.82.02.02.0-2.0-2.02.01.91.62.01.7-1.71.31.52.0-1.91.8-0.0
Food consumed during 24 hour testing period0.30.43.20.2-0.2-0.3-0.80.0-0.0-0.3-0.5-0.50.50.5-0.5-0.30.2-0.30.0-0.0-0.40.3-0.71.0-1.11.8
Glucose0.91.32.9-1.01.01.21.6-1.11.11.11.01.0-1.0-1.01.01.01.01.11.1-1.11.30.81.4-1.71.7-0.6
Heart weight1.11.74.8-0.90.91.12.0-1.21.11.11.01.0-1.0-1.01.01.10.91.41.2-1.21.50.61.5-2.12.2-1.7
Delay discount hyperbolic model param0.91.04.71.0-1.0-0.9-0.51.2-1.2-0.9-0.6-0.60.60.6-0.6-0.8-1.3-0.8-1.21.2-1.3-1.4-0.50.3-0.3-2.2
Intermittent access intake day 1-15 change0.10.20.7-0.20.20.20.2-0.70.70.30.20.2-0.2-0.20.20.30.70.20.8-0.80.50.7-0.1-0.1-0.00.7
Intermittent access intake escalation0.10.10.4-0.00.00.10.1-0.50.50.30.30.3-0.3-0.30.30.30.50.00.6-0.70.20.5-0.20.0-0.10.4
Intermittent access intake escalation 20.10.10.3-0.10.10.10.1-0.40.40.20.00.0-0.0-0.00.00.10.50.10.5-0.50.40.4-0.1-0.10.00.4
Intermitt. access day 1 inactive lever presses0.31.01.7-0.90.90.90.8-0.80.81.11.31.3-1.3-1.31.31.20.80.90.8-0.80.80.80.9-0.70.70.6
Intermitt. access day 15 inactive lever presses0.10.30.40.5-0.5-0.6-0.60.5-0.5-0.6-0.6-0.60.60.6-0.6-0.5-0.5-0.6-0.50.5-0.4-0.5-0.60.5-0.5-0.2
Intermitt. access escalation Index0.20.22.6-0.40.40.3-0.2-0.40.40.30.30.3-0.3-0.30.30.30.60.20.4-0.40.30.7-0.10.4-0.51.6
Intermittent access day 1 total infusions0.40.62.9-0.50.60.71.00.0-0.10.60.70.7-0.7-0.70.70.5-0.20.6-0.20.20.4-0.41.2-1.31.4-1.7
Intermittent access day 15 total infusions0.00.00.60.2-0.2-0.10.10.1-0.10.00.10.1-0.1-0.10.10.0-0.2-0.1-0.10.1-0.2-0.3-0.0-0.10.1-0.8
Intermittent access terminal intake (last 3 days)0.30.40.7-0.60.60.60.8-0.50.40.70.80.8-0.8-0.80.80.70.40.60.4-0.40.60.30.8-0.80.8-0.4
Intermittent access total infusions0.50.61.3-0.60.70.71.0-0.30.30.70.90.9-0.9-0.90.90.70.20.70.2-0.20.30.01.1-1.11.1-1.0
Intermittent access day 1 locomotion0.40.52.50.5-0.5-0.5-0.31.0-1.0-0.5-0.2-0.20.20.2-0.2-0.4-1.1-0.4-1.11.1-0.8-1.2-0.00.10.1-1.6
Intermittent access day 15 total locomotion0.10.21.7-0.10.10.20.6-0.00.00.30.40.4-0.4-0.40.40.3-0.10.20.0-0.00.1-0.30.5-0.70.8-1.3
Intermittent access total locomotion0.20.32.4-0.00.00.10.40.3-0.40.20.40.4-0.4-0.40.40.2-0.50.1-0.40.5-0.2-0.60.6-0.60.7-1.5
Intermittent access standard deviation4.18.510.2-3.13.13.13.2-3.02.93.12.82.8-2.8-2.82.82.92.93.22.9-2.93.12.73.1-3.13.11.0
Left kidney weight1.36.18.1-2.52.52.62.8-2.62.62.62.22.2-2.2-2.22.22.32.52.72.5-2.52.72.32.6-2.72.70.6
Right kidney weight0.41.83.6-1.21.21.31.9-1.41.41.31.11.1-1.1-1.11.11.11.21.51.4-1.31.51.01.5-1.91.9-0.7
Cocaine induced anxiety0.10.20.7-0.10.00.10.2-0.70.70.20.20.2-0.2-0.20.20.20.70.20.9-0.90.40.7-0.20.0-0.10.4
Post-drug Anxiety0.10.10.40.4-0.4-0.30.1-0.20.2-0.2-0.3-0.30.30.3-0.3-0.20.1-0.20.3-0.30.1-0.0-0.3-0.10.1-0.6
Baseline Anxiety0.10.10.60.1-0.1-0.1-0.10.6-0.6-0.2-0.2-0.20.20.2-0.2-0.2-0.6-0.2-0.70.8-0.3-0.60.2-0.10.2-0.5
Tail length0.20.71.90.5-0.5-0.7-1.00.2-0.2-0.6-1.1-1.11.11.1-1.1-0.90.0-0.7-0.00.0-0.10.1-1.01.0-1.11.4
Length with tail0.83.55.3-1.91.91.91.8-2.22.22.01.51.5-1.5-1.51.51.72.31.82.3-2.32.32.21.5-1.71.61.8
Length without tail2.99.311.9-3.13.13.23.4-3.13.13.23.13.1-3.1-3.13.13.12.93.13.0-3.03.12.73.2-3.43.30.7
Times rat made contact with spout0.40.50.80.5-0.5-0.6-0.80.7-0.7-0.6-0.9-0.90.90.9-0.9-0.7-0.6-0.7-0.70.7-0.4-0.5-0.60.8-0.80.5
Lifetime Intake0.60.81.8-0.80.80.91.2-0.40.40.91.01.0-1.0-1.01.00.80.20.90.2-0.20.40.11.3-1.31.3-1.2
Liver weight, left1.62.73.2-1.81.81.81.7-1.61.61.71.71.7-1.7-1.71.71.71.61.81.5-1.51.51.51.8-1.71.60.6
Liver weight, right0.91.72.2-1.41.41.41.1-1.41.41.21.21.2-1.2-1.21.21.31.51.21.4-1.41.41.51.2-1.11.01.4
Locomotor activity0.00.00.40.1-0.1-0.1-0.10.2-0.2-0.10.10.1-0.1-0.10.1-0.0-0.2-0.1-0.30.3-0.6-0.2-0.10.2-0.20.0
Locomotor testing distance0.10.10.3-0.30.30.3-0.00.4-0.40.10.40.4-0.4-0.40.40.2-0.30.3-0.50.5-0.4-0.20.40.00.00.3
Locomotor testing rearing0.71.42.51.1-1.1-1.2-1.51.4-1.3-1.3-0.8-0.80.80.8-0.8-1.0-1.3-1.2-1.41.4-1.6-1.1-1.21.5-1.50.2
Locomotion in novel chamber0.70.92.30.6-0.6-0.8-1.50.9-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.6-0.8-0.90.9-0.9-0.4-1.01.5-1.51.4
Locomotion in novel chamber post-restriction0.30.52.4-0.91.00.80.1-0.30.30.70.80.8-0.8-0.80.80.60.50.80.1-0.10.40.70.7-0.10.01.5
Fecal boli incidents, locomotor time 10.10.20.6-0.10.10.10.10.6-0.6-0.10.00.0-0.0-0.00.00.0-0.60.0-0.70.7-0.1-0.60.5-0.40.4-0.6
Change in fecal boli incidents, locomotor task0.00.00.40.0-0.0-0.00.20.0-0.0-0.0-0.1-0.10.10.1-0.1-0.1-0.10.0-0.00.0-0.1-0.20.1-0.20.3-0.6
Time >=10cm from walls, locomotor time 10.10.22.1-0.20.20.0-0.5-0.10.10.00.10.1-0.1-0.10.10.10.20.00.0-0.0-0.20.4-0.30.6-0.71.4
Bouts of movement, locomotor time 10.00.00.50.2-0.2-0.10.20.0-0.0-0.10.00.0-0.0-0.00.0-0.0-0.2-0.30.0-0.00.1-0.30.0-0.30.3-0.7
Total resting periods, locomotor time 10.10.10.70.3-0.3-0.20.10.2-0.2-0.2-0.1-0.10.10.1-0.1-0.1-0.3-0.4-0.10.10.0-0.4-0.0-0.20.2-0.8
Rest time, locomotor task time 10.81.02.5-0.80.81.01.4-0.70.71.01.01.0-1.0-1.01.00.90.60.90.7-0.70.90.41.3-1.51.6-1.3
Distance moved, locomotor task time 10.40.61.60.7-0.7-0.8-1.10.5-0.4-0.8-0.8-0.80.80.8-0.8-0.7-0.3-0.7-0.40.4-0.7-0.2-1.11.2-1.30.9
Vertical activity count, locomotor time 11.02.43.41.5-1.6-1.7-1.81.4-1.4-1.7-1.8-1.81.81.8-1.8-1.5-1.2-1.7-1.21.2-1.1-1.1-1.81.7-1.70.3
Time >=10cm from walls, locomotor time 20.20.40.70.7-0.7-0.7-0.50.4-0.4-0.7-0.6-0.60.60.6-0.6-0.7-0.4-0.6-0.30.3-0.9-0.4-0.70.7-0.7-0.6
Bouts of movement, locomotor time 20.20.40.7-0.70.70.70.6-0.40.40.70.60.6-0.6-0.60.60.60.40.50.3-0.30.70.40.8-0.70.70.2
Total resting periods, locomotor time 20.20.40.9-0.80.80.80.6-0.40.40.80.70.7-0.7-0.70.70.70.40.60.3-0.30.80.40.9-0.70.70.3
Rest time, locomotor task time 21.21.52.8-1.51.51.41.2-0.70.71.41.41.4-1.4-1.41.41.30.81.20.6-0.61.50.81.7-1.41.50.3
Distance moved, locomotor task time 20.60.71.41.1-1.1-1.0-0.70.3-0.3-0.9-0.9-0.90.90.9-0.9-0.8-0.4-0.8-0.20.2-1.0-0.5-1.20.8-0.8-0.7
Vertical activity count, locomotor time 20.30.40.70.8-0.8-0.8-0.40.5-0.5-0.8-0.9-0.90.90.9-0.9-0.7-0.6-0.8-0.40.4-0.4-0.7-0.70.2-0.2-0.8
Light reinforcement 12.15.27.02.5-2.5-2.5-2.22.2-2.2-2.2-2.5-2.52.52.5-2.5-2.3-2.2-2.6-2.12.1-1.8-2.3-2.42.0-1.9-1.6
Light reinforcement 20.50.71.51.0-1.0-1.0-0.90.5-0.5-0.6-1.1-1.11.11.1-1.1-0.9-0.4-1.1-0.30.3-0.2-0.5-1.20.8-0.8-0.2
Bone: marrow area1.53.310.4-2.52.62.21.0-0.90.91.82.02.0-2.0-2.02.02.01.31.80.6-0.61.81.62.2-1.21.23.2
Bone: maximum diameter9.417.522.4-4.74.74.63.9-3.93.94.44.54.5-4.5-4.54.54.54.04.43.6-3.64.14.04.4-3.83.63.3
Bone: maximum force2.23.86.0-2.12.12.22.4-1.71.72.12.12.1-2.1-2.12.12.01.52.21.5-1.51.51.42.4-2.22.2-0.1
Bone: maximum moment2.54.36.6-2.22.22.32.5-1.81.82.22.32.3-2.3-2.32.32.11.62.41.6-1.61.51.52.6-2.32.3-0.1
Mean time between licks in bursts0.00.00.1-0.20.20.20.2-0.20.20.00.30.3-0.3-0.30.30.20.20.20.2-0.2-0.30.20.2-0.10.00.2
Mean num. licks in bursts0.40.61.10.7-0.6-0.7-0.81.0-1.0-0.7-0.8-0.80.80.8-0.8-0.7-0.9-0.6-1.01.0-0.8-0.9-0.50.7-0.7-0.3
Cd content in liver0.80.92.40.9-0.9-0.8-0.51.2-1.2-0.9-0.7-0.70.70.7-0.7-0.8-1.3-0.9-1.21.3-1.0-1.4-0.40.3-0.2-1.6
Co content in liver0.00.00.1-0.00.00.00.10.1-0.10.10.20.2-0.2-0.20.20.1-0.10.1-0.10.1-0.1-0.10.1-0.00.0-0.3
Cu content in liver0.10.10.3-0.30.30.30.2-0.30.30.40.20.2-0.2-0.20.20.20.30.20.3-0.30.30.30.2-0.10.10.6
Fe content in liver0.10.21.8-0.10.1-0.0-0.60.2-0.1-0.2-0.4-0.40.40.4-0.4-0.30.0-0.0-0.20.2-0.10.2-0.30.6-0.71.4
K content in liver0.50.51.60.7-0.8-0.8-1.00.6-0.6-0.7-0.4-0.40.40.4-0.4-0.5-0.5-0.6-0.60.5-1.0-0.4-1.01.2-1.30.3
Mg content in liver2.62.64.31.7-1.7-1.7-1.91.7-1.7-1.7-1.3-1.31.31.3-1.3-1.5-1.7-1.6-1.81.8-2.1-1.6-1.71.9-1.9-0.4
Mn content in liver0.10.10.3-0.20.20.20.0-0.40.40.10.10.1-0.1-0.10.10.00.40.30.4-0.4-0.10.4-0.00.2-0.20.6
Na content in liver0.10.10.5-0.10.10.0-0.30.0-0.00.00.50.5-0.5-0.50.50.20.10.1-0.10.1-0.50.2-0.20.6-0.60.7
Rb content in liver1.72.02.41.5-1.5-1.5-1.41.5-1.5-1.5-1.4-1.41.41.4-1.4-1.5-1.5-1.3-1.41.4-1.6-1.4-1.41.3-1.3-0.8
Se content in liver1.41.63.11.2-1.2-1.3-1.71.2-1.2-1.3-1.2-1.21.21.2-1.2-1.3-1.0-1.3-1.21.2-1.3-0.9-1.51.7-1.80.4
Sr content in liver0.10.10.8-0.00.00.10.4-0.10.00.10.30.3-0.3-0.30.30.2-0.10.30.0-0.0-0.1-0.20.3-0.30.4-0.9
Zn content in liver0.10.10.2-0.20.20.30.3-0.30.30.40.40.4-0.4-0.40.40.40.20.20.3-0.30.50.20.3-0.40.40.1
Bone: minimum diameter3.76.89.4-2.92.92.82.1-2.32.32.83.13.1-3.1-3.13.12.92.42.72.1-2.12.22.52.6-2.01.92.6
Time in familiar zone, hab. session 10.10.10.20.4-0.4-0.4-0.20.2-0.2-0.3-0.2-0.20.20.2-0.2-0.2-0.3-0.5-0.20.2-0.0-0.3-0.40.1-0.1-0.5
Time in novel zone, hab. session 10.30.30.6-0.50.50.50.3-0.60.60.50.60.6-0.6-0.60.60.50.70.40.6-0.60.10.70.3-0.10.00.8
Total zone transitions, hab. session 12.02.84.01.7-1.7-1.6-1.61.7-1.7-1.6-1.8-1.81.81.8-1.8-1.8-1.7-1.4-1.71.7-2.0-1.7-1.51.7-1.7-0.9
Total locomotion distance, hab. session 11.92.73.11.8-1.8-1.7-1.51.6-1.6-1.7-1.7-1.71.71.7-1.7-1.7-1.7-1.5-1.61.6-1.7-1.7-1.61.5-1.4-1.2
Locomotion velocity, hab. session 12.53.54.02.0-2.0-2.0-1.71.9-1.9-1.9-2.0-2.02.02.0-2.0-2.0-2.0-1.7-1.91.9-2.0-2.0-1.71.6-1.5-1.4
Time in familiar zone, hab. session 20.10.10.80.2-0.2-0.10.00.3-0.3-0.0-0.0-0.00.00.0-0.0-0.0-0.3-0.1-0.30.3-0.1-0.40.0-0.10.2-0.9
Time in novel zone, hab. session 20.40.40.9-0.70.70.70.5-0.60.70.60.80.8-0.8-0.80.80.70.70.70.6-0.60.40.80.6-0.30.21.0
Total zone transitions, hab. session 25.47.09.32.6-2.6-2.6-2.53.0-3.0-2.6-2.6-2.62.62.6-2.6-2.7-3.0-2.4-3.03.0-3.0-3.0-2.22.3-2.2-2.0
Total locomotion distance, hab. session 25.87.59.62.9-2.9-2.8-2.43.0-3.0-2.8-2.7-2.72.72.7-2.7-2.8-3.0-2.6-2.92.9-3.0-3.1-2.42.1-2.0-2.7
Locomotion velocity, hab. session 26.08.19.83.0-3.0-2.9-2.53.0-3.0-2.9-2.9-2.92.92.9-2.9-3.0-3.1-2.7-2.92.9-3.1-3.1-2.52.3-2.1-2.6
Novel to familiar place preference ratio1.61.73.31.2-1.2-1.2-1.21.7-1.7-1.3-1.0-1.01.01.0-1.0-1.2-1.7-1.2-1.81.8-1.6-1.7-0.81.1-1.0-0.9
Novelty place preference1.21.32.51.0-1.0-1.0-1.11.5-1.5-1.1-0.9-0.90.90.9-0.9-1.0-1.5-1.0-1.61.6-1.4-1.4-0.70.9-0.9-0.7
Time in novel zone, NPP test1.51.63.01.1-1.1-1.1-1.21.6-1.6-1.3-1.0-1.01.01.0-1.0-1.1-1.6-1.2-1.71.7-1.6-1.6-0.81.1-1.0-0.9
Total zone transitions, NPP test4.46.37.82.6-2.6-2.6-2.42.6-2.6-2.5-2.6-2.62.62.6-2.6-2.6-2.6-2.5-2.52.5-2.8-2.6-2.42.3-2.2-1.9
Total locomotion distance, NPP test7.610.412.93.5-3.5-3.4-2.83.4-3.4-3.3-3.3-3.33.33.3-3.3-3.3-3.5-3.3-3.33.3-3.3-3.6-2.92.5-2.3-3.1
Locomotion velocity, NPP test6.59.111.23.2-3.2-3.2-2.63.2-3.2-3.1-3.1-3.13.13.1-3.1-3.1-3.3-3.1-3.13.1-3.1-3.4-2.72.3-2.1-2.9
Intraocular pressure0.30.51.30.1-0.1-0.3-0.51.0-1.0-0.5-0.9-0.90.90.9-0.9-0.7-0.9-0.4-1.11.1-0.1-0.80.10.10.0-0.3
Delta distance traveled before/after self-admin1.61.73.31.1-1.0-1.1-1.11.7-1.7-1.3-1.2-1.21.21.2-1.2-1.3-1.7-1.1-1.81.8-1.4-1.6-0.70.9-0.8-1.1
Delta ambulatory time before/after self-admin1.72.04.01.1-1.1-1.2-1.31.9-1.9-1.4-1.2-1.21.21.2-1.2-1.4-1.8-1.2-2.02.0-1.7-1.7-0.81.2-1.1-0.9
Parametrial fat weight0.00.00.2-0.10.20.10.20.1-0.10.20.00.0-0.0-0.00.00.0-0.10.1-0.10.10.3-0.10.3-0.40.4-0.3
Pavlov. Cond. lever latency0.20.20.70.0-0.0-0.2-0.60.7-0.7-0.3-0.4-0.40.40.4-0.4-0.4-0.6-0.1-0.80.8-0.4-0.4-0.00.4-0.40.2
Pavlov. Cond. magazine entry latency2.32.93.9-1.71.61.61.3-1.91.91.71.91.9-1.9-1.91.91.81.91.61.9-1.91.52.01.2-1.10.91.9
Pavlov. Cond. change in total contacts0.20.21.40.4-0.4-0.20.10.4-0.4-0.30.00.0-0.0-0.00.0-0.2-0.6-0.2-0.40.4-0.5-0.70.1-0.10.2-1.2
Pavlov. Cond. index score1.11.42.0-1.01.01.11.1-1.41.41.21.31.3-1.3-1.31.31.31.31.01.4-1.41.11.30.8-0.90.80.9
Pavlov. Cond. latency score1.41.82.8-1.11.11.21.3-1.61.61.31.41.4-1.4-1.41.41.41.61.11.7-1.71.31.50.9-1.11.01.0
Pavlov. Cond. lever contacts0.10.10.20.1-0.10.00.4-0.40.40.10.20.2-0.2-0.20.20.20.2-0.00.4-0.40.20.10.0-0.40.3-0.4
Pavlov. Cond. magazine entry number2.73.44.11.8-1.8-1.8-1.72.0-2.0-1.8-2.0-2.02.02.0-2.0-2.0-2.0-1.8-2.02.0-1.6-2.0-1.61.5-1.3-1.5
Pavlov. Cond. intertrial magazine entries2.12.53.01.6-1.5-1.6-1.61.7-1.7-1.7-1.6-1.61.61.6-1.6-1.6-1.7-1.5-1.71.7-1.4-1.6-1.41.5-1.4-0.8
Pavlov. Cond. lever-magazine prob. diff.0.81.01.3-0.80.80.90.9-1.11.10.91.11.1-1.1-1.11.11.11.10.81.1-1.10.81.00.7-0.70.60.8
Pavlov. Cond. response bias1.41.82.2-1.21.21.31.3-1.51.51.31.51.5-1.5-1.51.51.41.41.21.5-1.51.11.41.1-1.11.00.8
Pavlov. Cond. lever latency0.81.01.9-0.70.70.91.4-1.31.21.00.80.8-0.8-0.80.80.81.10.71.3-1.31.20.90.8-1.31.2-0.6
Pavlov. Cond. magazine entry latency0.10.20.70.0-0.0-0.00.10.6-0.6-0.2-0.1-0.10.10.1-0.1-0.1-0.6-0.0-0.70.7-0.1-0.70.4-0.40.5-0.8
Pavlov. Cond. change in total contacts0.50.82.00.7-0.7-0.8-0.91.3-1.3-0.9-0.7-0.70.70.7-0.7-0.7-1.3-0.6-1.41.4-0.9-1.2-0.50.6-0.5-0.7
Pavlov. Cond. index score0.40.51.30.5-0.5-0.6-0.71.1-1.1-0.7-0.5-0.50.50.5-0.5-0.6-1.0-0.4-1.11.1-0.6-0.9-0.30.5-0.4-0.2
Pavlov. Cond. latency score0.20.20.80.2-0.2-0.3-0.60.8-0.8-0.5-0.3-0.30.30.3-0.3-0.3-0.7-0.2-0.90.9-0.4-0.6-0.10.3-0.30.1
Pavlov. Cond. lever contacts1.31.82.71.1-1.1-1.2-1.71.6-1.6-1.3-1.3-1.31.31.3-1.3-1.2-1.4-1.1-1.61.6-1.4-1.2-1.11.5-1.50.4
Pavlov. Cond. magazine entry number0.20.30.7-0.30.30.40.3-0.80.80.50.40.4-0.4-0.40.40.40.80.40.8-0.80.30.80.1-0.1-0.00.7
Pavlov. Cond. intertrial magazine entries0.60.84.10.5-0.5-0.7-1.40.5-0.5-0.7-0.7-0.70.70.7-0.7-0.7-0.2-0.9-0.50.5-0.70.0-1.21.6-1.72.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.20.4-0.4-0.5-0.71.0-1.0-0.6-0.5-0.50.50.5-0.5-0.5-0.9-0.4-1.11.1-0.6-0.9-0.30.5-0.4-0.1
Pavlov. Cond. response bias1.01.32.31.0-1.0-1.1-1.21.5-1.5-1.1-1.1-1.11.11.1-1.1-1.1-1.4-0.9-1.51.5-1.1-1.4-0.80.9-0.8-0.5
Time in closed arm before self-admin0.20.22.0-0.00.00.20.7-0.40.40.30.20.2-0.2-0.20.20.30.20.30.4-0.40.40.00.3-0.70.7-1.4
Time in closed arm after self-admin1.11.11.6-1.11.11.21.2-0.90.91.21.21.2-1.2-1.21.21.20.81.10.8-0.81.10.81.3-1.21.2-0.1
Time in open arm before self-admin0.00.00.1-0.20.20.2-0.0-0.10.10.00.20.2-0.2-0.20.20.10.20.10.1-0.1-0.30.20.10.2-0.20.3
Time in open arm after self-admin0.80.81.10.8-0.8-0.9-1.01.0-1.0-1.0-0.9-0.90.90.9-0.9-1.0-0.9-0.9-1.01.0-1.0-0.9-0.81.0-1.0-0.2
Bone: periosteal estimation3.88.111.3-3.33.43.22.7-2.32.33.03.13.1-3.1-3.13.13.12.43.02.1-2.12.82.53.3-2.82.72.2
Bone: periosteal perimeter8.314.316.3-4.04.04.03.7-3.73.74.04.04.0-4.0-4.04.04.03.73.93.6-3.63.73.73.8-3.53.42.5
Bone: post-yield work0.10.20.7-0.00.00.0-0.10.7-0.7-0.20.10.1-0.1-0.10.1-0.1-0.70.1-0.80.8-0.5-0.60.40.00.0-0.5
Progressive ratio test 1 active lever presses0.10.10.70.1-0.1-0.1-0.00.5-0.5-0.1-0.1-0.10.10.1-0.1-0.3-0.5-0.1-0.60.6-0.4-0.60.2-0.10.2-0.8
Progressive ratio test 1 breakpoint0.10.10.60.1-0.1-0.1-0.00.5-0.5-0.1-0.1-0.10.10.1-0.1-0.3-0.5-0.1-0.60.6-0.4-0.60.2-0.10.2-0.8
Progressive ratio test 1 inactive lever presses0.00.00.1-0.20.20.20.2-0.20.20.30.30.3-0.3-0.30.30.20.10.20.1-0.10.10.10.2-0.20.2-0.1
Progressive ratio test 2 active lever presses0.30.32.60.4-0.4-0.30.00.7-0.7-0.2-0.1-0.10.10.1-0.1-0.3-0.8-0.3-0.70.7-0.7-0.90.1-0.20.3-1.6
Progressive ratio test 2 breakpoint0.20.32.50.3-0.3-0.20.10.5-0.6-0.10.00.0-0.0-0.00.0-0.2-0.7-0.2-0.60.6-0.6-0.80.2-0.30.4-1.6
Progressive ratio test 2 inactive lever presses0.10.10.9-0.00.00.10.5-0.10.10.20.20.2-0.2-0.20.20.10.00.10.1-0.10.1-0.10.3-0.50.5-0.9
Incentive Sensitization - Responses0.40.61.1-0.50.50.71.0-0.70.60.80.90.9-0.9-0.90.90.80.50.70.6-0.60.50.40.8-1.01.0-0.8
Incentive Sensitization - Breakpoint0.60.71.3-0.60.60.81.1-0.80.80.91.01.0-1.0-1.01.00.90.60.80.8-0.70.60.50.9-1.11.1-0.8
Sum of active levers in priming session hrs 5-60.40.41.2-0.80.80.80.7-0.10.10.60.70.7-0.7-0.70.70.60.10.7-0.00.10.30.11.1-0.80.9-0.4
Progressive ratio0.30.51.6-0.60.60.60.90.0-0.00.50.70.7-0.7-0.70.70.7-0.10.5-0.10.20.5-0.21.1-1.11.3-1.1
Food seeking constrained by brief footshock1.31.62.4-1.21.21.31.5-1.21.21.31.41.4-1.4-1.41.41.41.11.11.2-1.21.41.01.4-1.51.50.0
Seeking ratio, punishment vs. effort0.10.21.0-0.20.20.20.0-0.60.60.20.10.1-0.1-0.10.10.20.70.20.7-0.70.30.7-0.20.2-0.31.0
Retroperitoneal fat weight0.00.10.5-0.20.20.1-0.20.2-0.20.1-0.2-0.20.20.2-0.2-0.0-0.0-0.1-0.20.20.50.00.1-0.00.00.7
Reaction time number correct2.64.96.02.1-2.1-2.2-2.52.3-2.3-2.3-2.4-2.42.42.4-2.4-2.3-2.1-2.3-2.32.3-2.1-2.0-2.12.3-2.2-0.3
Reaction time mean minus median0.20.40.9-0.40.40.50.9-0.90.90.60.50.5-0.5-0.50.50.50.70.41.0-1.00.60.60.5-0.80.8-0.3
Reaction time mean minus median AUC0.30.71.6-0.60.60.60.7-1.21.20.80.70.7-0.7-0.70.70.71.10.51.3-1.30.71.10.3-0.50.50.5
Reaction time num false alarms0.00.00.10.0-0.0-0.1-0.10.2-0.20.20.30.3-0.3-0.30.30.3-0.2-0.2-0.10.10.2-0.20.0-0.20.2-0.2
Reaction time num false alarms AUC0.00.10.20.2-0.2-0.2-0.30.5-0.5-0.00.10.1-0.1-0.10.10.1-0.4-0.3-0.50.5-0.1-0.4-0.1-0.00.1-0.3
Reaction time trials correct on left2.64.96.02.1-2.1-2.2-2.52.3-2.3-2.3-2.4-2.42.42.4-2.4-2.3-2.1-2.3-2.32.3-2.1-2.0-2.12.3-2.2-0.3
Reaction time trials on left2.64.85.92.0-2.0-2.2-2.42.3-2.3-2.2-2.4-2.42.42.4-2.4-2.3-2.1-2.3-2.32.3-2.0-2.0-2.12.3-2.2-0.3
Reaction time mean0.00.00.1-0.20.20.20.3-0.10.10.10.10.1-0.1-0.10.10.00.10.10.1-0.1-0.10.00.3-0.30.3-0.3
Reaction time mean AUC0.00.00.3-0.00.00.10.30.0-0.0-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.0-0.10.1-0.2-0.20.2-0.30.3-0.6
Median of all reaction times0.00.00.1-0.20.20.20.2-0.00.0-0.00.10.1-0.1-0.10.10.1-0.00.1-0.00.1-0.1-0.00.3-0.20.2-0.2
Reaction time omissions0.71.02.0-1.01.00.91.0-1.21.21.10.70.7-0.7-0.70.70.91.20.71.3-1.31.41.20.7-1.00.90.9
Reaction time false alarm rate0.70.91.8-0.80.80.90.9-0.70.71.11.31.3-1.3-1.31.31.20.70.80.7-0.70.90.60.9-1.01.1-0.1
Reaction time premature initiation rate2.63.56.71.9-1.9-1.8-1.42.1-2.1-1.8-1.7-1.71.71.7-1.7-2.0-2.3-1.7-2.22.2-2.2-2.4-1.31.2-1.1-2.6
Reaction time premature initiations4.37.710.52.7-2.7-2.7-2.53.2-3.2-2.8-2.7-2.72.72.7-2.7-2.9-3.2-2.7-3.23.2-3.0-3.2-2.12.2-2.1-2.5
Std. dev. reaction times0.00.10.4-0.00.00.10.4-0.30.30.1-0.0-0.00.00.0-0.0-0.10.2-0.00.3-0.3-0.00.10.2-0.40.4-0.7
Reaction time trials completed2.64.85.92.0-2.0-2.2-2.42.3-2.3-2.2-2.4-2.42.42.4-2.4-2.3-2.1-2.3-2.32.3-2.0-2.0-2.12.3-2.2-0.3
Reaction time trials AUC3.05.86.82.3-2.2-2.4-2.62.5-2.5-2.5-2.6-2.62.62.6-2.6-2.5-2.4-2.5-2.52.5-2.3-2.2-2.32.4-2.4-0.5
Run reversals in cocaine runway, females0.20.21.3-0.40.40.40.5-0.50.50.4-0.1-0.10.10.1-0.10.20.50.30.6-0.61.10.40.4-0.70.70.2
Run reversals in cocaine runway, males0.40.41.7-0.40.40.50.9-0.10.10.40.50.5-0.5-0.50.50.5-0.00.30.1-0.10.6-0.20.9-1.11.2-1.3
Latency to leave start box in cocaine runway0.10.21.40.3-0.3-0.30.00.5-0.5-0.2-0.1-0.10.10.1-0.1-0.2-0.6-0.2-0.50.5-0.4-0.60.0-0.20.2-1.2
Latency to leave start box in cocaine runway, F0.40.51.20.7-0.7-0.7-0.50.8-0.8-0.7-0.5-0.50.50.5-0.5-0.6-0.8-0.8-0.80.8-0.7-0.9-0.50.4-0.4-1.1
Latency to leave start box in cocaine runway, M0.10.10.6-0.10.10.20.40.2-0.20.10.20.2-0.2-0.20.20.1-0.30.3-0.30.3-0.2-0.40.5-0.50.6-0.8
Std. dev. time between licks in bursts2.12.83.71.6-1.6-1.7-1.91.6-1.6-1.7-1.8-1.81.81.8-1.8-1.7-1.5-1.8-1.61.6-1.8-1.4-1.71.9-1.80.2
Total sessions with >9 infusions2.32.85.8-1.71.81.82.1-1.01.01.71.81.8-1.8-1.81.81.60.91.90.8-0.81.30.72.4-2.32.4-1.1
Short access day 1 total inactive lever presses1.82.43.1-1.61.61.71.7-1.51.51.71.71.7-1.7-1.71.71.61.41.81.3-1.31.21.41.7-1.51.50.2
Short access day 10 total inactive lever presses0.30.63.1-0.60.60.50.1-0.90.90.70.70.7-0.7-0.70.70.81.00.51.0-1.00.61.20.00.1-0.31.8
Short access day 1 total infusions1.62.24.2-1.61.61.71.9-1.11.11.61.51.5-1.5-1.51.51.40.91.80.9-0.91.00.82.0-1.92.0-0.7
Short access day 10 total infusions2.22.85.5-2.02.02.01.8-1.11.11.81.91.9-1.9-1.91.91.71.01.90.8-0.81.41.02.3-2.02.00.1
Short access total infusions1.21.53.3-1.31.31.41.6-0.60.61.31.31.3-1.3-1.31.31.20.51.40.5-0.40.80.41.8-1.71.8-1.0
Short access day 1 locomotion0.91.12.2-1.11.11.21.4-0.70.71.11.11.1-1.1-1.11.11.00.51.30.5-0.50.70.41.5-1.41.5-0.7
Short access day 10 total locomotion0.71.32.1-1.21.21.21.3-0.90.81.21.31.3-1.3-1.31.31.20.81.30.7-0.71.10.71.5-1.41.4-0.2
Short access total locomotion2.53.05.0-1.71.71.82.1-1.31.31.82.02.0-2.0-2.02.01.81.21.91.2-1.21.41.02.2-2.22.2-0.7
One hour access (0.3 mA shock)0.30.32.10.3-0.3-0.30.00.7-0.7-0.3-0.4-0.40.40.4-0.4-0.4-0.8-0.3-0.70.7-0.5-0.90.2-0.20.4-1.5
Compulsive drug intake0.40.50.70.8-0.8-0.7-0.60.7-0.7-0.8-0.8-0.80.80.8-0.8-0.8-0.7-0.7-0.70.7-0.6-0.7-0.70.6-0.5-0.7
One hour access (shock baseline)0.00.00.2-0.20.20.20.3-0.00.00.20.10.1-0.1-0.10.10.1-0.00.1-0.00.00.2-0.00.4-0.40.4-0.3
Social response proportion0.30.31.00.5-0.5-0.5-0.20.5-0.5-0.5-0.8-0.80.80.8-0.8-0.6-0.5-0.5-0.40.4-0.2-0.6-0.3-0.00.1-1.0
Social responses0.30.40.90.7-0.8-0.7-0.40.2-0.2-0.7-0.9-0.90.90.9-0.9-0.7-0.3-0.6-0.10.1-0.5-0.4-0.80.5-0.5-0.5
Social time0.30.41.60.7-0.7-0.6-0.20.4-0.5-0.6-0.7-0.70.70.7-0.7-0.7-0.6-0.6-0.40.4-0.4-0.7-0.50.10.0-1.3
Soleus weight0.61.93.61.6-1.6-1.4-0.71.0-1.0-1.4-1.7-1.71.71.7-1.7-1.6-1.2-1.4-0.90.9-1.0-1.4-1.20.6-0.5-1.9
Bone: stiffness1.83.04.2-1.71.71.92.1-1.71.71.81.81.8-1.8-1.81.81.81.51.81.6-1.61.51.42.0-1.91.90.1
Tibialis anterior weight0.10.51.70.7-0.6-0.5-0.10.6-0.6-0.6-0.9-0.90.90.9-0.9-0.8-0.8-0.4-0.60.6-0.4-0.9-0.20.00.0-1.3
Time to tail flick, vehicle, before self-admin0.40.40.70.8-0.8-0.7-0.40.4-0.4-0.7-0.7-0.70.70.7-0.7-0.8-0.5-0.7-0.30.3-0.7-0.5-0.70.5-0.5-0.6
Time to tail flick, vehicle, after self-admin1.62.13.0-1.21.21.31.7-1.41.41.51.51.5-1.5-1.51.51.61.31.41.5-1.51.61.11.4-1.71.7-0.5
Time to tail flick, test, before self-admin1.31.42.31.1-1.1-1.2-1.41.0-1.0-1.2-1.2-1.21.21.2-1.2-1.3-0.9-1.3-1.00.9-1.2-0.8-1.41.5-1.50.3
Time to tail flick, test, after self-admin2.02.12.6-1.51.51.51.5-1.61.61.51.31.3-1.3-1.31.31.41.61.51.6-1.61.51.61.4-1.41.30.8
Delta time to tail flick, vehicle, before/after SA1.01.01.4-1.01.01.00.9-0.80.81.11.11.1-1.1-1.11.11.20.91.00.8-0.81.20.81.0-1.00.90.5
Delta time to tail flick, test, before/after SA3.43.54.4-1.81.81.92.1-2.02.01.91.91.9-1.9-1.91.92.01.91.92.1-2.11.91.81.8-2.02.00.4
Tibia length11.732.243.5-5.65.65.65.5-6.56.55.95.35.3-5.3-5.35.35.66.55.36.6-6.66.46.44.7-5.04.84.2
Ambulatory time before self-admin0.50.71.7-0.60.60.60.7-1.21.20.80.60.6-0.6-0.60.60.81.20.51.3-1.31.21.10.3-0.60.50.6
Ambulatory time after self-admin0.50.51.20.5-0.5-0.6-0.71.0-1.0-0.7-0.6-0.60.60.6-0.6-0.7-0.9-0.6-1.11.1-0.8-0.9-0.40.6-0.6-0.5
Bone: tissue strength0.20.21.70.1-0.1-0.00.00.6-0.6-0.20.10.1-0.1-0.10.1-0.2-0.70.1-0.70.8-1.0-0.70.30.00.0-1.3
Total heroin consumption3.23.85.4-2.32.32.21.8-1.71.72.12.12.1-2.1-2.12.12.11.72.21.5-1.41.81.82.2-1.81.71.5
Bone: trabecular number0.20.31.00.4-0.4-0.5-0.80.6-0.6-0.6-0.3-0.30.30.3-0.3-0.4-0.5-0.6-0.70.7-0.8-0.4-0.50.9-1.00.5
Bone: trabecular spacing0.10.10.6-0.30.30.30.4-0.40.40.4-0.1-0.10.10.1-0.10.10.40.30.5-0.50.80.30.3-0.60.60.2
Bone: trabecular thickness0.20.20.70.2-0.1-0.2-0.40.6-0.6-0.4-0.1-0.10.10.1-0.1-0.2-0.6-0.0-0.80.8-0.9-0.5-0.10.5-0.5-0.0
Bone: trabecular tissue density0.10.10.30.2-0.3-0.3-0.1-0.30.30.1-0.4-0.40.40.4-0.4-0.20.3-0.40.4-0.40.50.2-0.4-0.10.10.3
Water consumed over 24 hours0.60.81.40.9-1.0-1.0-1.00.6-0.6-0.8-1.1-1.11.11.1-1.1-0.9-0.6-1.0-0.50.5-0.7-0.5-1.21.1-1.10.2
Number of responses in last shaping day2.32.63.7-1.61.61.71.9-1.51.41.71.71.7-1.7-1.71.71.71.31.81.4-1.41.41.21.8-1.91.9-0.1