Hub : Genes

Birc5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Birc5 0.12 0.06 5.6e-17 0.15 0.14 0.14 0.14 8.3e-16 1.0e-15 4.7e-15 2.9e-15
2 Adipose alternative TSS XM_039086783.1 0.02 0.02 3.3e-04 0.03 0.03 0.03 0.03 5.5e-04 5.1e-04 6.3e-04 6.3e-04
3 Liver intron excision ratio chr10_103078604_103080841 0.03 0.02 1.6e-03 0.01 0.02 0.01 0 7.1e-02 6.1e-03 1.4e-02 1.5e-01
4 Liver intron excision ratio chr10_103077852_103080841 0.03 0.02 1.4e-03 0.01 0.02 0.01 0 6.5e-02 5.5e-03 1.3e-02 1.2e-01
5 PL alternative TSS NM_022274.2 0.05 0.04 9.8e-06 0.04 0.04 0.04 0.04 1.1e-05 5.2e-05 2.2e-05 2.1e-05
6 PL alternative TSS XM_039086783.1 0.06 0.04 1.5e-06 0.06 0.05 0.05 0.05 1.0e-06 7.3e-06 1.6e-06 1.8e-06
7 PL isoform ratio NM_022274.2 0.04 0.04 1.9e-04 0.04 0.03 0.03 0.04 5.5e-05 3.0e-04 5.8e-04 8.4e-05
8 Brain gene expression Birc5 0.12 0.06 1.3e-08 0.1 0.1 0.1 0.1 7.6e-10 1.4e-09 2.8e-09 8.5e-10
9 NAcc gene expression Birc5 0.14 0.08 5.0e-08 0.06 0.06 0.06 0.06 5.3e-08 2.8e-07 5.7e-07 7.8e-08
10 BLA gene expression Birc5 0.15 0.08 2.8e-07 0.11 0.13 0.12 0.12 1.2e-06 1.8e-07 4.8e-07 4.0e-07
11 BLA alternative TSS NM_022274.2 0.09 0.08 3.6e-03 0.04 0.01 0.01 0.02 5.5e-03 1.4e-01 8.9e-02 1.8e-02
12 BLA alternative TSS XM_039086783.1 0.08 0.07 4.2e-03 0.03 0.01 0.01 0.02 6.6e-03 1.5e-01 1.0e-01 2.3e-02
13 Adipose alternative TSS NM_022274.2 0.02 0.02 4.0e-04 0.03 0.03 0.02 0.02 6.5e-04 7.0e-04 1.0e-03 8.7e-04
14 IL gene expression Birc5 0.19 0.14 1.0e-03 0.09 0.06 0.03 0.06 3.9e-03 1.2e-02 8.2e-02 1.5e-02
15 Liver gene expression Birc5 0.41 0.13 0.0e+00 0.36 0.37 0.37 0.37 2.1e-42 5.3e-43 6.7e-43 5.0e-43
16 NAcc alternative TSS XM_039086783.1 0.07 0.05 4.4e-06 0.04 0.04 0.04 0.04 1.7e-05 6.0e-06 5.6e-06 7.1e-06
17 NAcc alternative TSS NM_022274.2 0.06 0.04 8.6e-06 0.04 0.04 0.04 0.04 2.2e-05 1.2e-05 5.4e-06 7.1e-06
18 OFC gene expression Birc5 0.21 0.15 1.2e-03 0.05 0.07 0.1 0.05 2.9e-02 9.3e-03 2.5e-03 2.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.50.92.60.5-1.4-1.61.6-0.50.5-0.50.50.5-1.2-0.70.7-0.50.5-0.51.5-1.5-0.1
Area under the delay curve0.70.83.6-0.61.21.1-1.10.6-0.60.6-0.5-0.50.51.0-1.00.5-0.50.5-0.80.8-1.9
BMI with tail0.31.114.0-0.50.00.2-0.20.4-0.40.4-0.3-0.31.60.6-0.60.2-0.20.2-0.60.63.7
BMI without tail1.12.36.51.5-1.5-1.51.5-1.61.6-1.61.61.6-0.8-1.21.2-1.61.6-1.61.1-1.12.6
Body weight0.52.25.7-1.31.61.8-1.81.2-1.21.2-1.1-1.12.41.5-1.51.1-1.11.1-1.81.81.3
Weight adjusted by age0.10.10.2-0.30.1-0.00.00.3-0.30.3-0.3-0.30.20.4-0.40.3-0.30.3-0.30.3-0.2
Bone surface0.71.24.2-1.30.60.2-0.31.2-1.21.2-1.2-1.20.21.3-1.31.2-1.21.1-0.60.6-2.0
Bone volume0.20.31.5-0.6-0.3-0.60.60.6-0.60.6-0.5-0.5-0.40.5-0.50.5-0.50.50.1-0.1-1.2
Breakpoint value in progressive ratio session0.50.61.9-0.8-0.1-0.30.30.7-0.70.7-0.8-0.80.60.9-0.90.8-0.80.8-0.90.91.4
Number of licking bursts0.10.10.30.30.20.2-0.2-0.50.5-0.50.50.50.10.1-0.1-0.50.5-0.5-0.00.00.1
Context. condit. distance diff. score0.40.50.9-0.80.40.3-0.30.8-0.80.8-0.9-0.90.50.6-0.60.9-0.90.9-0.70.70.3
Locomotion velocity, session 10.30.32.2-0.21.01.1-1.10.2-0.20.2-0.2-0.20.40.3-0.30.1-0.10.2-0.30.3-1.5
Locomotion distance, session 12.93.84.72.0-1.9-1.71.7-2.12.1-2.12.12.1-1.7-2.12.1-2.22.2-2.21.7-1.70.9
Locomotion velocity, session 20.50.60.80.7-0.9-0.90.9-0.70.7-0.70.60.6-0.8-0.80.8-0.70.7-0.70.9-0.90.2
Locomotion distance, session 25.57.79.32.9-3.0-2.92.9-2.82.8-2.82.82.8-2.6-2.82.8-2.82.8-2.83.1-3.11.1
Locomotion velocity, session 30.30.32.20.50.30.4-0.4-0.50.5-0.50.50.5-0.4-0.60.6-0.40.4-0.40.1-0.1-1.5
Locomotion distance, session 30.30.41.20.7-0.3-0.10.1-0.70.7-0.70.50.5-0.1-0.70.7-0.60.6-0.60.4-0.41.1
Stereotopy head waving bouts, day 32.83.34.3-1.81.51.4-1.42.0-2.02.0-2.0-2.01.72.0-2.01.9-1.91.9-2.12.1-0.4
Stereotopy head waving duration, day 32.93.54.6-2.01.51.3-1.32.1-2.12.1-2.0-2.01.62.1-2.12.0-2.02.0-2.02.0-0.8
Locomotion velocity, session 70.20.20.50.4-0.3-0.30.3-0.50.5-0.50.40.4-0.7-0.50.5-0.40.4-0.40.5-0.4-0.5
Locomotion distance, session 72.63.34.91.7-2.2-2.22.2-1.81.8-1.81.71.7-1.9-1.81.8-1.51.5-1.62.0-2.01.0
Stereotopy head waving bouts, day 74.14.65.4-2.22.22.1-2.12.2-2.22.2-2.3-2.32.12.3-2.32.2-2.22.2-2.22.2-0.7
Stereotopy head waving duration, day 76.27.58.5-2.82.82.7-2.72.9-2.92.9-2.9-2.92.42.9-2.92.8-2.82.8-2.62.6-2.0
Locomotion velocity, session 80.50.52.5-0.70.70.6-0.60.8-0.80.8-0.7-0.70.20.6-0.60.7-0.70.7-0.50.5-1.6
Locomotion distance, session 82.23.24.91.7-2.2-2.22.2-1.71.7-1.71.61.6-1.8-1.81.8-1.61.6-1.61.7-1.71.6
Degree of sensitization distance2.92.95.21.5-2.1-2.32.3-1.51.5-1.51.61.6-2.2-1.51.5-1.41.4-1.51.9-1.9-0.2
Degree of sensitization stereotypy1.71.82.2-1.41.51.4-1.41.4-1.41.4-1.5-1.51.41.3-1.31.3-1.31.3-1.31.3-0.5
Conditioned locomotion0.30.30.50.7-0.6-0.60.6-0.70.7-0.70.70.7-0.5-0.30.3-0.70.7-0.70.2-0.20.5
Cocaine response after cond. corrected0.40.40.9-0.50.50.5-0.50.5-0.50.5-0.6-0.60.80.8-0.80.6-0.60.6-1.01.00.5
Cocaine response after cond. not corrected0.10.10.3-0.20.30.3-0.30.2-0.20.2-0.3-0.30.30.3-0.30.3-0.30.3-0.60.5-0.2
Cocaine response before conditioning0.40.52.40.4-0.3-0.40.4-0.50.5-0.50.50.5-1.1-0.80.8-0.50.5-0.50.9-0.9-1.6
Saline control response1.21.62.51.30.00.1-0.1-1.51.5-1.51.51.5-1.4-1.11.1-1.51.5-1.50.9-0.9-1.6
Bone: connectivity density1.01.63.80.9-1.5-1.61.6-0.90.9-0.90.90.9-1.7-1.11.1-0.90.9-1.01.9-1.9-0.5
Bone: cortical apparent density0.70.93.00.7-1.3-1.21.2-0.80.8-0.80.70.7-0.4-0.70.7-0.70.7-0.71.3-1.31.7
Bone: cortical area3.85.88.2-2.62.22.2-2.22.5-2.52.5-2.5-2.52.92.5-2.52.5-2.52.5-2.52.50.2
Bone: cortical porosity2.32.53.7-1.81.61.5-1.51.7-1.71.7-1.7-1.71.31.5-1.51.6-1.61.6-1.21.2-1.9
Bone: cortical porosity3.13.44.6-2.01.81.7-1.82.0-2.02.0-2.0-2.01.51.8-1.81.9-1.91.9-1.51.5-2.1
Bone: cortical thickness0.61.04.1-0.90.91.2-1.20.8-0.80.8-0.7-0.71.90.8-0.80.7-0.70.7-0.70.72.0
Bone: cortical thickness0.20.31.4-0.40.60.8-0.80.3-0.30.3-0.3-0.31.20.4-0.40.2-0.20.3-0.30.30.8
Bone: cortical tissue density0.71.02.80.7-1.3-1.31.3-0.80.8-0.80.70.7-0.5-0.80.8-0.70.7-0.71.3-1.31.7
Condit. Reinf. active minus inactive responses0.20.20.40.5-0.4-0.40.4-0.40.4-0.40.30.3-0.7-0.30.3-0.50.5-0.50.4-0.4-0.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.1-0.5-0.70.70.2-0.20.2-0.2-0.2-0.60.1-0.10.1-0.10.10.4-0.4-0.5
Condit. Reinf. active responses1.11.42.11.4-0.9-0.80.8-1.31.3-1.31.21.2-1.3-1.21.2-1.41.4-1.41.0-1.0-0.3
Condit. Reinf. inactive responses2.02.43.71.9-0.9-0.80.8-1.91.9-1.91.81.8-1.3-1.71.7-1.91.9-1.81.0-1.00.3
Incentive salience index mean0.10.10.30.4-0.1-0.20.2-0.30.3-0.30.30.3-0.5-0.20.2-0.40.4-0.40.3-0.3-0.6
Condit. Reinf. lever presses0.30.40.70.7-0.3-0.30.3-0.90.9-0.90.80.8-0.5-0.50.5-0.80.8-0.80.4-0.4-0.3
Condit. Reinf. active minus inactive responses0.30.32.1-0.60.60.5-0.50.6-0.60.6-0.5-0.50.10.3-0.30.5-0.50.5-0.40.4-1.4
Condit. Reinf. active-inactive response ratio0.10.10.7-0.20.40.4-0.40.1-0.10.1-0.1-0.1-0.10.0-0.00.1-0.10.1-0.10.1-0.8
Condit. Reinf. active responses0.00.10.2-0.1-0.3-0.40.40.1-0.10.1-0.0-0.0-0.5-0.20.2-0.00.0-0.00.2-0.2-0.5
Condit. Reinf. inactive responses0.50.61.10.6-1.0-1.11.1-0.60.6-0.60.60.6-1.0-0.80.8-0.60.6-0.60.8-0.80.1
Condit. Reinf. lever presses1.01.32.31.0-1.4-1.51.5-1.11.1-1.11.11.1-1.5-1.11.1-1.11.1-1.11.2-1.2-0.1
Condit. Reinf. lever reinforcers received0.10.10.5-0.1-0.6-0.70.70.0-0.00.0-0.0-0.0-0.4-0.20.2-0.00.0-0.00.3-0.30.1
Conditioned reinforcement - actives0.80.81.10.8-1.0-1.01.0-0.80.8-0.80.80.8-0.7-0.90.9-0.90.9-0.90.9-0.90.8
Conditioned reinforcement - inactives0.30.40.5-0.70.60.6-0.60.7-0.70.7-0.7-0.70.60.5-0.50.7-0.70.7-0.40.4-0.3
Conditioned locomotion0.70.91.70.8-1.3-1.31.3-0.80.8-0.80.80.8-0.7-0.80.8-0.80.8-0.81.0-0.91.1
Patch foraging indifference point 0 sec1.01.62.21.2-1.5-1.51.5-1.21.2-1.21.31.3-1.4-1.51.5-1.31.3-1.20.9-0.90.9
Patch foraging indifference point AUC3.23.74.82.0-1.5-1.41.4-2.12.1-2.12.12.1-2.1-2.12.1-2.22.2-2.21.9-1.90.3
Delay disc. indifference point, 0s delay1.01.14.3-0.91.31.4-1.40.8-0.80.8-0.8-0.80.70.9-0.90.8-0.80.8-0.80.8-2.1
Delay disc. indifference point, 16s delay0.40.40.60.7-0.6-0.60.6-0.80.8-0.80.70.7-0.7-0.30.3-0.80.8-0.80.6-0.60.3
Delay disc. indifference point, 2s delay0.30.33.1-0.30.70.7-0.70.2-0.20.2-0.2-0.20.20.7-0.70.2-0.20.2-0.40.4-1.8
Delay disc. indifference point, 24s delay0.10.10.10.3-0.1-0.20.1-0.30.3-0.30.40.4-0.40.0-0.0-0.40.4-0.40.2-0.2-0.3
Delay disc. indifference point, 4s delay0.90.94.1-0.71.31.3-1.30.7-0.70.7-0.6-0.60.51.1-1.10.6-0.60.6-0.80.8-2.0
Delay disc. indifference point, 8s delay2.93.05.9-1.52.22.2-2.21.5-1.51.5-1.4-1.41.31.8-1.81.4-1.41.4-1.71.7-2.4
Indifference point function ln k0.91.22.3-1.20.30.3-0.31.2-1.21.2-1.2-1.21.51.1-1.11.3-1.31.3-0.90.91.4
Indifference point function log k0.91.22.3-1.20.30.3-0.31.2-1.21.2-1.2-1.21.51.1-1.11.3-1.31.3-0.90.91.4
Patch foraging total patch changes 0 sec1.32.13.11.4-1.7-1.81.8-1.41.4-1.41.41.4-1.5-1.71.7-1.41.4-1.41.1-1.11.0
Patch foraging total patch changes 12 sec5.47.09.42.8-2.5-2.42.4-2.82.8-2.82.82.8-2.7-3.13.1-2.82.8-2.82.2-2.21.3
Patch foraging total patch changes 18 sec3.74.76.02.2-2.0-2.12.1-2.22.2-2.22.42.4-2.5-2.22.2-2.42.4-2.41.7-1.70.6
Patch foraging total patch changes 24 sec0.10.11.10.20.1-0.0-0.0-0.10.1-0.10.30.3-0.7-0.50.5-0.30.3-0.3-0.30.3-1.0
Patch foraging total patch changes 6 sec2.74.05.22.1-1.9-1.81.8-2.12.1-2.12.22.2-1.9-1.91.9-2.32.3-2.31.7-1.71.6
Patch foraging time to switch 0 sec0.30.40.6-0.60.80.8-0.80.6-0.60.6-0.7-0.70.70.7-0.70.7-0.70.7-0.50.5-0.3
Patch foraging water rate 0 sec1.01.62.11.4-1.2-1.21.2-1.41.4-1.41.51.5-1.4-1.51.5-1.41.4-1.40.7-0.70.3
Patch foraging water rate 12 sec0.30.56.90.0-0.5-0.50.50.1-0.10.1-0.0-0.00.50.1-0.10.1-0.10.1-0.30.32.6
Patch foraging water rate 18 sec0.10.21.00.1-0.7-0.80.8-0.20.2-0.20.20.2-0.2-0.10.1-0.20.2-0.20.3-0.31.0
Patch foraging water rate 24 sec1.92.73.31.6-1.8-1.81.8-1.81.8-1.81.81.8-1.4-1.41.4-1.71.7-1.71.1-1.11.7
Patch foraging water rate 6 sec0.10.11.40.1-0.3-0.20.2-0.20.2-0.20.30.30.2-0.20.2-0.30.3-0.3-0.20.21.2
Seeking ratio, delayed vs. immediate footshock0.20.30.70.4-0.3-0.30.3-0.30.3-0.30.30.3-0.8-0.80.8-0.20.2-0.30.9-0.9-0.8
Distance traveled before self-admin0.90.93.6-0.61.21.2-1.20.9-0.90.9-0.9-0.90.60.7-0.70.9-0.90.9-0.70.7-1.9
Distance traveled after self-admin1.01.12.60.8-1.5-1.61.6-0.90.9-0.90.90.9-1.2-0.90.9-0.90.9-0.91.0-1.00.9
Extensor digitorum longus weight1.45.56.52.6-2.4-2.22.3-2.52.5-2.52.42.4-1.7-2.22.2-2.52.5-2.52.1-2.12.3
Bone: elastic displacement0.60.71.20.8-1.0-0.90.9-0.80.8-0.80.80.8-0.5-0.80.8-0.70.7-0.71.0-0.91.1
Bone: elastic work0.70.91.9-1.00.60.7-0.70.9-0.90.9-0.9-0.91.41.0-1.01.0-1.01.0-0.90.91.0
Bone: endosteal estimation1.12.43.2-1.80.80.4-0.41.7-1.71.7-1.7-1.70.81.8-1.81.7-1.71.7-1.71.7-1.4
Bone: endosteal perimeter4.49.111.8-3.22.62.2-2.23.1-3.13.1-3.1-3.12.23.4-3.43.1-3.13.1-3.13.1-3.3
Epididymis fat weight0.20.53.1-0.40.20.3-0.30.4-0.40.4-0.3-0.31.10.6-0.60.4-0.40.4-0.90.91.8
Delta time in closed arm before/after self-admin0.20.20.4-0.50.60.5-0.50.5-0.50.5-0.5-0.50.10.5-0.50.4-0.40.4-0.60.6-0.5
Delta time in open arm before/after self-admin1.61.52.11.2-1.1-1.01.0-1.31.3-1.31.31.3-1.2-1.31.3-1.21.2-1.21.4-1.4-0.4
Diff in mean of infusions in LGA sessions1.01.12.0-1.30.50.3-0.31.0-1.01.0-1.0-1.01.01.4-1.41.1-1.11.1-1.31.30.4
Delay discount exponential model param1.01.04.30.8-1.3-1.31.3-0.70.7-0.70.70.7-0.7-1.21.2-0.70.7-0.71.0-1.02.1
Extinction: sum of active levers before priming0.10.10.5-0.30.00.0-0.00.2-0.20.2-0.1-0.10.40.3-0.30.1-0.10.1-0.30.30.7
Active lever presses in extinction session 60.30.34.20.0-0.4-0.50.5-0.20.2-0.20.30.30.00.1-0.1-0.30.3-0.3-0.20.22.1
Bone: final force1.62.73.4-1.81.51.5-1.51.7-1.71.7-1.7-1.71.91.8-1.81.7-1.71.7-1.51.50.3
Bone: final moment1.93.13.9-2.01.61.6-1.51.9-1.91.9-1.9-1.91.92.0-2.01.8-1.81.8-1.61.60.3
Food consumed during 24 hour testing period0.40.41.60.6-0.0-0.10.0-0.80.8-0.80.70.7-0.8-0.40.4-0.70.7-0.70.3-0.3-1.3
Glucose0.10.20.9-0.40.10.2-0.10.4-0.40.4-0.3-0.30.80.6-0.60.3-0.30.30.1-0.11.0
Heart weight0.60.92.3-0.90.50.6-0.60.9-0.90.9-0.9-0.91.50.8-0.80.9-0.90.9-0.90.91.5
Delay discount hyperbolic model param0.90.94.10.7-1.3-1.21.2-0.70.7-0.70.60.6-0.6-1.11.1-0.60.6-0.60.9-0.92.0
Intermittent access intake day 1-15 change0.10.11.20.10.50.6-0.6-0.00.0-0.00.00.0-0.1-0.20.2-0.00.0-0.00.2-0.2-1.1
Intermittent access intake escalation0.20.21.40.30.20.3-0.3-0.20.2-0.20.20.2-0.5-0.40.4-0.20.2-0.20.4-0.4-1.2
Intermittent access intake escalation 20.50.50.80.9-0.2-0.20.2-0.80.8-0.80.70.7-0.8-0.80.8-0.80.8-0.80.8-0.8-0.4
Intermitt. access day 1 inactive lever presses2.52.73.1-1.81.71.6-1.61.8-1.81.8-1.8-1.81.41.6-1.61.7-1.71.7-1.51.5-1.4
Intermitt. access day 15 inactive lever presses0.50.50.70.7-0.6-0.60.5-0.80.8-0.80.80.8-0.8-0.80.8-0.80.8-0.80.8-0.8-0.0
Intermitt. access escalation Index0.60.51.1-0.70.80.7-0.70.6-0.60.6-0.7-0.70.30.7-0.70.7-0.70.7-0.70.7-1.0
Intermittent access day 1 total infusions0.40.50.9-0.80.20.2-0.10.7-0.70.7-0.7-0.70.90.7-0.70.7-0.70.7-0.80.80.9
Intermittent access day 15 total infusions0.00.00.1-0.20.10.1-0.10.2-0.20.2-0.3-0.30.00.1-0.10.2-0.20.2-0.10.1-0.3
Intermittent access terminal intake (last 3 days)0.20.20.3-0.50.40.4-0.40.6-0.60.6-0.6-0.60.40.5-0.50.5-0.50.5-0.50.5-0.2
Intermittent access total infusions0.30.40.5-0.70.30.2-0.20.7-0.70.7-0.7-0.70.60.6-0.60.7-0.70.7-0.60.60.3
Intermittent access day 1 locomotion0.30.31.20.3-0.9-0.90.9-0.30.3-0.30.30.3-0.3-0.30.3-0.40.4-0.40.4-0.41.1
Intermittent access day 15 total locomotion0.20.20.4-0.50.20.2-0.20.6-0.60.6-0.6-0.60.60.4-0.40.6-0.60.6-0.40.40.3
Intermittent access total locomotion0.10.10.70.2-0.6-0.60.6-0.10.1-0.10.10.1-0.1-0.20.2-0.20.2-0.20.3-0.30.8
Intermittent access standard deviation4.54.85.8-2.12.42.4-2.42.2-2.22.2-2.2-2.22.42.2-2.22.2-2.22.2-2.22.2-0.8
Left kidney weight3.18.811.1-2.93.23.2-3.23.0-3.03.0-2.9-2.93.33.0-3.02.9-2.92.9-3.33.3-1.1
Right kidney weight1.23.44.7-1.92.02.1-2.01.9-1.91.9-1.8-1.82.21.7-1.71.8-1.81.8-1.91.9-0.7
Cocaine induced anxiety0.30.31.7-0.30.80.8-0.80.4-0.40.4-0.4-0.40.10.4-0.40.4-0.40.4-0.30.3-1.3
Post-drug Anxiety0.20.30.50.7-0.1-0.10.1-0.60.6-0.60.60.6-0.7-0.50.5-0.50.5-0.50.3-0.3-0.6
Baseline Anxiety0.00.00.40.2-0.2-0.10.1-0.10.1-0.10.10.10.1-0.10.1-0.10.1-0.1-0.00.00.6
Tail length0.51.52.31.5-0.7-0.70.7-1.41.4-1.41.41.4-1.4-1.21.2-1.31.3-1.30.9-0.9-1.2
Length with tail0.82.94.8-1.42.22.2-2.21.4-1.41.4-1.4-1.41.71.6-1.61.5-1.51.5-2.02.0-1.9
Length without tail4.49.612.1-3.13.23.3-3.33.2-3.23.2-3.1-3.13.53.1-3.13.1-3.13.1-3.23.2-0.9
Times rat made contact with spout0.50.60.90.7-0.6-0.60.6-0.90.9-0.90.80.8-0.8-0.60.6-0.80.8-0.80.8-0.8-0.1
Lifetime Intake0.50.60.8-0.90.50.4-0.40.9-0.90.9-0.9-0.90.90.8-0.80.8-0.80.8-0.80.80.6
Liver weight, left3.25.26.5-2.32.32.3-2.32.4-2.42.4-2.3-2.32.42.6-2.62.3-2.32.3-2.32.3-0.5
Liver weight, right0.81.32.3-0.81.41.5-1.51.0-1.01.0-0.9-0.91.51.2-1.20.9-0.90.9-1.31.3-0.2
Locomotor activity0.00.00.4-0.0-0.2-0.20.20.0-0.00.0-0.1-0.1-0.1-0.20.20.1-0.10.10.1-0.1-0.7
Locomotor testing distance0.20.30.5-0.6-0.1-0.30.30.6-0.60.6-0.7-0.70.10.4-0.40.7-0.70.7-0.20.2-0.7
Locomotor testing rearing0.91.42.41.1-1.4-1.41.4-1.11.1-1.11.01.0-1.5-1.31.3-1.01.0-1.01.5-1.4-0.6
Locomotion in novel chamber0.81.02.10.9-0.8-1.01.0-1.01.0-1.01.01.0-1.4-0.90.9-1.11.1-1.11.1-1.1-0.8
Locomotion in novel chamber post-restriction0.20.30.4-0.60.20.0-0.00.6-0.60.6-0.6-0.60.10.6-0.60.5-0.50.5-0.50.5-0.3
Fecal boli incidents, locomotor time 10.20.20.80.1-0.8-0.90.9-0.10.1-0.10.10.1-0.1-0.10.1-0.20.2-0.20.2-0.20.9
Change in fecal boli incidents, locomotor task0.10.10.10.3-0.3-0.20.2-0.20.2-0.20.20.2-0.0-0.30.3-0.20.2-0.20.1-0.10.3
Time >=10cm from walls, locomotor time 10.10.11.5-0.20.20.1-0.10.2-0.20.2-0.2-0.2-0.3-0.10.10.2-0.20.20.2-0.2-1.2
Bouts of movement, locomotor time 10.00.00.1-0.0-0.00.1-0.1-0.00.0-0.00.10.10.3-0.30.3-0.00.0-0.00.1-0.10.1
Total resting periods, locomotor time 10.00.00.10.0-0.2-0.10.1-0.10.1-0.10.10.10.2-0.30.3-0.10.1-0.10.4-0.40.0
Rest time, locomotor task time 10.60.71.3-0.90.50.5-0.50.9-0.90.9-0.9-0.91.10.7-0.70.9-0.90.9-0.50.51.1
Distance moved, locomotor task time 10.50.51.10.8-0.4-0.40.4-0.80.8-0.80.80.8-1.0-0.50.5-0.80.8-0.80.6-0.6-0.4
Vertical activity count, locomotor time 12.32.43.31.8-1.3-1.21.2-1.81.8-1.81.81.8-1.7-1.41.4-1.81.8-1.81.2-1.20.1
Time >=10cm from walls, locomotor time 20.30.30.80.5-0.5-0.40.4-0.50.5-0.50.50.5-0.5-0.70.7-0.50.5-0.50.9-0.90.1
Bouts of movement, locomotor time 20.40.40.7-0.80.40.4-0.30.8-0.80.8-0.8-0.80.60.5-0.50.8-0.80.8-0.50.60.1
Total resting periods, locomotor time 20.50.50.8-0.90.40.3-0.30.9-0.90.9-0.9-0.90.60.6-0.60.9-0.90.9-0.50.5-0.0
Rest time, locomotor task time 21.21.42.1-1.40.70.5-0.51.4-1.41.4-1.4-1.41.21.0-1.01.4-1.41.4-1.11.10.1
Distance moved, locomotor task time 20.40.40.80.9-0.2-0.10.1-0.80.8-0.80.80.8-0.5-0.60.6-0.80.8-0.80.5-0.50.2
Vertical activity count, locomotor time 20.40.40.80.9-0.4-0.30.3-0.80.8-0.80.80.8-0.4-0.60.6-0.70.7-0.70.2-0.20.5
Light reinforcement 12.74.85.92.3-2.0-1.91.9-2.42.4-2.42.42.4-2.1-2.42.4-2.42.4-2.41.8-1.81.5
Light reinforcement 20.60.81.21.0-0.3-0.20.2-1.01.0-1.01.11.1-0.7-1.11.1-1.11.1-1.10.3-0.30.6
Bone: marrow area1.12.53.3-1.80.80.4-0.41.8-1.81.8-1.8-1.80.81.8-1.81.7-1.71.7-1.71.7-1.5
Bone: maximum diameter8.114.917.5-4.23.53.2-3.24.1-4.14.1-4.1-4.13.64.1-4.14.1-4.14.1-3.93.9-2.4
Bone: maximum force2.13.64.8-2.21.51.4-1.42.1-2.12.1-2.0-2.02.12.1-2.12.0-2.02.0-1.81.80.9
Bone: maximum moment2.44.15.4-2.31.51.4-1.42.2-2.22.2-2.2-2.22.22.3-2.32.2-2.22.2-1.91.90.9
Mean time between licks in bursts0.10.10.5-0.10.10.1-0.10.3-0.30.3-0.3-0.30.20.2-0.20.3-0.30.30.4-0.4-0.7
Mean num. licks in bursts0.30.30.90.5-0.9-1.01.0-0.30.3-0.30.30.3-0.8-0.70.7-0.30.3-0.30.8-0.80.2
Cd content in liver0.50.62.90.6-0.8-0.70.8-0.60.6-0.60.60.6-0.1-0.50.5-0.50.5-0.51.0-1.01.7
Co content in liver0.30.31.80.2-0.8-0.90.9-0.20.2-0.20.20.2-0.4-0.40.4-0.20.2-0.20.5-0.51.4
Cu content in liver0.00.00.1-0.00.10.2-0.20.0-0.00.0-0.0-0.00.2-0.00.00.0-0.00.0-0.40.4-0.1
Fe content in liver0.10.11.7-0.20.20.1-0.10.1-0.10.1-0.1-0.1-0.30.1-0.10.1-0.10.1-0.20.2-1.3
K content in liver0.10.10.70.1-0.0-0.10.1-0.10.1-0.10.00.0-0.6-0.30.30.0-0.00.00.2-0.2-0.8
Mg content in liver1.41.42.21.1-1.4-1.51.5-1.01.0-1.01.01.0-1.5-1.21.2-1.01.0-1.01.4-1.40.5
Mn content in liver0.50.51.2-0.51.11.1-1.10.5-0.50.5-0.5-0.50.60.8-0.80.5-0.50.5-0.90.9-0.4
Na content in liver0.40.41.7-0.60.60.6-0.60.6-0.60.6-0.6-0.60.10.5-0.50.6-0.60.6-0.50.5-1.3
Rb content in liver2.83.54.51.9-1.9-1.91.9-1.91.9-1.91.91.9-1.8-1.91.9-1.91.9-1.92.1-2.10.9
Se content in liver0.91.12.11.1-0.6-0.70.7-1.11.1-1.11.11.1-1.4-1.01.0-1.11.1-1.11.0-1.0-1.0
Sr content in liver0.20.20.9-0.40.30.4-0.40.4-0.40.4-0.4-0.40.50.3-0.30.4-0.40.4-0.40.41.0
Zn content in liver1.92.12.6-1.61.31.3-1.31.6-1.61.6-1.6-1.61.41.4-1.41.6-1.61.6-1.41.4-0.6
Bone: minimum diameter3.36.28.1-2.82.01.7-1.72.8-2.82.8-2.7-2.71.92.5-2.52.8-2.82.8-2.42.4-2.0
Time in familiar zone, hab. session 10.10.10.30.3-0.2-0.20.2-0.30.3-0.30.10.1-0.2-0.50.5-0.20.2-0.20.3-0.3-0.0
Time in novel zone, hab. session 10.30.30.5-0.60.70.6-0.60.5-0.50.5-0.4-0.40.40.6-0.60.5-0.50.5-0.30.3-0.7
Total zone transitions, hab. session 12.02.83.61.7-1.8-1.81.8-1.61.6-1.61.61.6-1.7-1.61.6-1.71.7-1.71.9-1.90.5
Total locomotion distance, hab. session 11.92.73.61.9-1.7-1.61.6-1.81.8-1.81.61.6-1.6-1.71.7-1.71.7-1.71.6-1.60.6
Locomotion velocity, hab. session 12.53.54.42.1-2.0-1.91.9-2.02.0-2.01.91.9-1.7-1.91.9-2.02.0-2.01.8-1.81.0
Time in familiar zone, hab. session 20.10.11.30.1-0.3-0.30.3-0.20.2-0.20.10.1-0.0-0.10.1-0.00.0-0.0-0.10.11.1
Time in novel zone, hab. session 20.50.50.8-0.80.60.6-0.60.8-0.80.8-0.8-0.80.50.7-0.70.8-0.80.7-0.40.4-0.9
Total zone transitions, hab. session 25.46.99.62.5-3.1-3.13.1-2.52.5-2.52.42.4-2.6-2.62.6-2.52.5-2.52.8-2.81.7
Total locomotion distance, hab. session 25.87.79.02.9-3.0-2.92.9-2.92.9-2.92.72.7-2.5-2.72.7-2.82.8-2.82.5-2.52.4
Locomotion velocity, hab. session 26.18.29.43.1-3.0-2.92.9-3.13.1-3.12.92.9-2.6-2.82.8-2.92.9-2.92.6-2.62.2
Novel to familiar place preference ratio1.41.43.30.8-1.7-1.81.8-0.80.8-0.80.90.9-1.3-1.31.3-0.80.8-0.81.4-1.41.0
Novelty place preference1.01.02.50.7-1.5-1.61.6-0.60.6-0.60.80.8-1.1-1.11.1-0.70.7-0.71.2-1.20.8
Time in novel zone, NPP test1.31.33.00.8-1.6-1.71.7-0.80.8-0.80.90.9-1.2-1.21.2-0.80.8-0.81.4-1.41.0
Total zone transitions, NPP test4.76.77.52.7-2.7-2.62.6-2.72.7-2.72.62.6-2.6-2.62.6-2.72.7-2.72.4-2.41.6
Total locomotion distance, NPP test8.111.113.23.6-3.4-3.33.3-3.63.6-3.63.43.4-2.9-3.43.4-3.53.5-3.53.0-3.02.7
Locomotion velocity, NPP test6.89.711.43.4-3.2-3.13.1-3.33.3-3.33.23.2-2.7-3.13.1-3.33.3-3.22.8-2.82.5
Intraocular pressure0.50.71.90.7-1.1-1.21.2-0.70.7-0.70.70.7-0.7-0.60.6-0.70.7-0.70.4-0.41.4
Delta distance traveled before/after self-admin2.52.74.71.2-2.1-2.22.2-1.41.4-1.41.51.5-1.5-1.41.4-1.51.5-1.51.6-1.62.1
Delta ambulatory time before/after self-admin2.83.05.51.3-2.2-2.32.3-1.51.5-1.51.61.6-1.7-1.41.4-1.61.6-1.61.6-1.62.2
Parametrial fat weight0.10.10.80.10.10.1-0.1-0.10.1-0.10.00.00.2-0.10.10.0-0.00.0-0.60.60.9
Pavlov. Cond. lever latency0.20.31.00.3-0.9-1.01.0-0.10.1-0.10.20.2-0.7-0.40.4-0.10.1-0.10.7-0.70.8
Pavlov. Cond. magazine entry latency1.82.33.5-1.51.81.7-1.81.3-1.31.3-1.3-1.31.21.5-1.51.3-1.31.3-1.71.7-1.9
Pavlov. Cond. change in total contacts0.10.10.3-0.1-0.4-0.40.4-0.10.1-0.10.10.10.10.0-0.0-0.10.1-0.10.3-0.30.5
Pavlov. Cond. index score1.01.22.1-1.01.41.5-1.50.8-0.80.8-0.9-0.91.11.2-1.20.7-0.70.7-1.41.4-1.1
Pavlov. Cond. latency score1.21.63.0-1.11.71.7-1.70.9-0.90.9-1.0-1.01.31.3-1.30.8-0.80.9-1.61.6-1.3
Pavlov. Cond. lever contacts0.10.10.20.00.40.5-0.5-0.20.2-0.20.10.10.40.1-0.1-0.30.3-0.2-0.40.4-0.1
Pavlov. Cond. magazine entry number2.93.64.32.0-2.1-2.02.0-1.81.8-1.81.81.8-1.8-2.12.1-1.71.7-1.72.1-2.11.5
Pavlov. Cond. intertrial magazine entries2.02.43.81.6-1.7-1.71.7-1.51.5-1.51.41.4-1.7-1.51.5-1.51.5-1.51.9-1.90.7
Pavlov. Cond. lever-magazine prob. diff.0.70.81.4-0.91.21.2-1.20.7-0.70.7-0.7-0.70.91.0-1.00.6-0.60.6-1.11.1-1.1
Pavlov. Cond. response bias1.21.51.9-1.31.41.4-1.41.1-1.11.1-1.1-1.11.21.3-1.31.0-1.01.0-1.41.4-1.0
Pavlov. Cond. lever latency0.91.22.7-0.91.51.6-1.60.9-0.90.9-0.9-0.91.40.9-0.90.9-0.90.9-1.21.2-0.0
Pavlov. Cond. magazine entry latency0.20.21.60.1-0.7-0.80.8-0.10.1-0.10.10.1-0.0-0.10.1-0.10.1-0.10.2-0.21.3
Pavlov. Cond. change in total contacts0.60.82.00.6-1.3-1.41.4-0.70.7-0.70.70.7-0.8-0.70.7-0.70.7-0.71.0-1.00.6
Pavlov. Cond. index score0.50.61.60.6-1.2-1.31.3-0.60.6-0.60.60.6-0.8-0.60.6-0.60.6-0.60.8-0.80.2
Pavlov. Cond. latency score0.20.31.00.4-0.9-1.01.0-0.40.4-0.40.40.4-0.6-0.40.4-0.40.4-0.40.6-0.60.2
Pavlov. Cond. lever contacts1.21.62.81.2-1.5-1.71.6-1.11.1-1.11.11.1-1.7-1.21.2-1.11.1-1.11.4-1.4-0.7
Pavlov. Cond. magazine entry number0.50.61.4-0.61.11.2-1.20.6-0.60.6-0.6-0.60.60.6-0.60.6-0.60.6-0.60.6-1.1
Pavlov. Cond. intertrial magazine entries0.60.83.10.9-0.4-0.50.5-0.80.8-0.80.80.8-1.5-0.90.9-0.80.8-0.80.5-0.5-1.8
Pavlov. Cond. lever-magazine prob. diff.0.60.71.80.7-1.2-1.31.3-0.70.7-0.70.70.7-0.9-0.70.7-0.70.7-0.70.9-0.90.3
Pavlov. Cond. response bias0.81.01.90.9-1.3-1.41.4-0.90.9-0.90.90.9-1.1-1.01.0-0.90.9-0.91.1-1.10.1
Time in closed arm before self-admin0.00.00.20.2-0.00.1-0.1-0.20.2-0.20.10.10.2-0.10.1-0.10.1-0.10.2-0.20.4
Time in closed arm after self-admin2.82.93.4-1.81.61.5-1.51.8-1.81.8-1.8-1.81.71.8-1.81.8-1.81.8-1.71.7-0.2
Time in open arm before self-admin0.50.50.7-0.80.70.6-0.60.8-0.80.8-0.8-0.80.70.7-0.70.7-0.70.7-0.70.70.3
Time in open arm after self-admin0.70.80.90.8-0.9-0.90.9-0.80.8-0.80.90.9-0.9-0.90.9-0.90.9-0.90.9-0.90.4
Bone: periosteal estimation3.26.68.5-2.92.01.7-1.72.8-2.82.8-2.8-2.82.42.8-2.82.8-2.82.8-2.72.7-1.0
Bone: periosteal perimeter6.510.912.4-3.53.23.0-3.03.4-3.43.4-3.4-3.43.33.5-3.53.4-3.43.4-3.53.5-1.8
Bone: post-yield work0.20.31.3-0.0-0.9-1.11.1-0.10.1-0.10.10.1-0.4-0.20.2-0.10.1-0.10.6-0.61.1
Progressive ratio test 1 active lever presses0.00.00.20.0-0.4-0.40.40.0-0.00.0-0.0-0.0-0.3-0.10.1-0.00.0-0.00.1-0.10.3
Progressive ratio test 1 breakpoint0.00.00.2-0.1-0.3-0.40.40.2-0.20.2-0.2-0.2-0.10.1-0.10.1-0.10.1-0.00.00.5
Progressive ratio test 1 inactive lever presses0.20.30.9-0.60.60.5-0.50.5-0.50.5-0.5-0.50.30.4-0.40.5-0.50.5-0.30.4-0.9
Progressive ratio test 2 active lever presses0.10.10.6-0.0-0.5-0.50.50.0-0.00.0-0.0-0.0-0.0-0.00.0-0.00.0-0.00.1-0.10.8
Progressive ratio test 2 breakpoint0.10.10.60.1-0.5-0.50.6-0.10.1-0.10.10.1-0.1-0.20.2-0.10.1-0.10.2-0.20.8
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.10.1-0.10.2-0.20.2-0.2-0.20.20.1-0.10.2-0.20.2-0.00.00.2
Incentive Sensitization - Responses0.70.71.4-0.90.80.8-0.80.8-0.80.8-0.8-0.81.20.9-0.90.8-0.80.8-0.90.90.2
Incentive Sensitization - Breakpoint0.90.91.6-1.11.01.0-1.01.0-1.01.0-0.9-0.91.31.0-1.00.9-0.90.9-1.11.10.1
Sum of active levers in priming session hrs 5-60.50.51.2-1.10.30.1-0.11.0-1.01.0-0.8-0.80.60.8-0.80.7-0.70.7-0.60.60.2
Progressive ratio0.20.30.6-0.4-0.1-0.10.20.5-0.50.5-0.6-0.60.60.4-0.40.5-0.50.5-0.60.70.8
Food seeking constrained by brief footshock0.81.01.4-1.00.91.0-1.01.0-1.01.0-1.0-1.01.20.9-0.91.0-1.01.0-1.21.2-0.2
Seeking ratio, punishment vs. effort0.10.21.3-0.30.60.7-0.70.1-0.10.1-0.1-0.10.10.2-0.20.2-0.20.2-0.10.1-1.1
Retroperitoneal fat weight0.30.92.4-0.81.11.2-1.10.7-0.70.7-0.7-0.71.31.0-1.00.7-0.70.7-1.51.50.3
Reaction time number correct4.46.47.92.6-2.4-2.52.4-2.72.7-2.72.82.8-2.6-2.32.3-2.82.8-2.82.2-2.31.5
Reaction time mean minus median0.60.71.4-0.81.01.2-1.20.8-0.80.8-0.8-0.81.00.6-0.60.9-0.90.9-0.80.8-0.4
Reaction time mean minus median AUC0.70.91.8-0.91.31.4-1.40.9-0.90.9-0.8-0.80.90.7-0.70.9-0.90.9-1.01.0-1.0
Reaction time num false alarms0.10.10.30.3-0.4-0.40.4-0.30.3-0.30.30.3-0.3-0.60.6-0.30.3-0.30.1-0.10.1
Reaction time num false alarms AUC0.20.30.60.5-0.8-0.80.8-0.40.4-0.40.40.4-0.6-0.80.8-0.40.4-0.40.4-0.40.2
Reaction time trials correct on left4.46.47.92.6-2.4-2.52.4-2.72.7-2.72.82.8-2.6-2.32.3-2.82.8-2.82.2-2.31.5
Reaction time trials on left4.46.27.82.6-2.4-2.42.4-2.62.6-2.62.82.8-2.5-2.32.3-2.72.7-2.72.2-2.21.5
Reaction time mean0.10.20.4-0.40.30.3-0.30.5-0.50.5-0.6-0.60.40.3-0.30.6-0.60.6-0.10.1-0.6
Reaction time mean AUC0.10.10.2-0.30.10.1-0.10.3-0.30.3-0.4-0.40.30.1-0.10.4-0.40.4-0.00.0-0.2
Median of all reaction times0.10.20.5-0.40.10.1-0.10.4-0.40.4-0.5-0.50.30.3-0.30.5-0.50.50.1-0.1-0.7
Reaction time omissions0.50.61.2-0.71.01.0-1.00.7-0.70.7-0.7-0.70.70.6-0.60.7-0.70.7-1.11.1-0.5
Reaction time false alarm rate0.50.61.0-0.90.50.5-0.50.9-0.90.9-1.0-1.00.70.5-0.51.0-1.01.0-0.80.8-0.7
Reaction time premature initiation rate1.92.64.21.5-2.0-2.02.0-1.41.4-1.41.41.4-1.3-1.41.4-1.51.5-1.51.8-1.82.0
Reaction time premature initiations5.17.39.82.6-3.1-3.13.1-2.62.6-2.62.62.6-2.4-2.42.4-2.62.6-2.62.7-2.72.8
Std. dev. reaction times0.10.10.3-0.30.40.5-0.50.4-0.40.4-0.4-0.40.50.2-0.20.4-0.40.4-0.30.3-0.0
Reaction time trials completed4.46.27.82.6-2.4-2.42.4-2.62.6-2.62.82.8-2.5-2.32.3-2.72.7-2.72.2-2.21.5
Reaction time trials AUC5.17.49.02.8-2.6-2.72.6-2.92.9-2.93.03.0-2.7-2.52.5-3.03.0-3.02.5-2.51.7
Run reversals in cocaine runway, females0.10.10.30.10.30.3-0.3-0.20.2-0.20.10.10.40.2-0.2-0.00.0-0.0-0.60.6-0.1
Run reversals in cocaine runway, males0.40.43.3-0.40.20.3-0.20.4-0.40.4-0.3-0.30.90.4-0.40.3-0.30.3-0.80.81.8
Latency to leave start box in cocaine runway0.20.21.70.1-0.6-0.60.6-0.00.0-0.0-0.0-0.0-0.1-0.30.3-0.10.1-0.10.2-0.21.3
Latency to leave start box in cocaine runway, F0.40.51.80.6-0.8-0.80.8-0.60.6-0.60.50.5-0.7-0.80.8-0.60.6-0.60.6-0.61.3
Latency to leave start box in cocaine runway, M0.30.30.90.4-0.9-0.91.0-0.30.3-0.30.30.3-0.2-0.40.4-0.40.4-0.40.6-0.60.9
Std. dev. time between licks in bursts2.12.63.41.7-1.6-1.61.6-1.71.7-1.71.71.7-1.8-1.71.7-1.71.7-1.71.5-1.5-0.1
Total sessions with >9 infusions1.71.92.5-1.51.01.0-1.01.5-1.51.5-1.5-1.51.61.5-1.51.4-1.41.4-1.41.40.8
Short access day 1 total inactive lever presses0.70.71.0-1.00.60.6-0.61.0-1.01.0-1.0-1.00.80.9-0.91.0-1.01.0-0.80.80.2
Short access day 10 total inactive lever presses0.80.91.4-1.01.21.2-1.21.0-1.01.0-1.0-1.00.70.8-0.81.0-1.00.9-0.70.7-1.1
Short access day 1 total infusions1.71.82.4-1.41.11.1-1.11.4-1.41.4-1.4-1.41.51.5-1.51.3-1.31.3-1.51.50.6
Short access day 10 total infusions2.12.43.1-1.71.21.0-1.01.7-1.71.7-1.7-1.71.61.7-1.71.6-1.61.6-1.81.80.2
Short access total infusions0.60.71.2-0.90.50.5-0.50.9-0.90.9-0.9-0.91.00.9-0.90.8-0.80.8-0.90.91.1
Short access day 1 locomotion0.50.50.8-0.70.60.6-0.60.7-0.70.7-0.7-0.70.90.8-0.80.7-0.70.7-0.80.80.4
Short access day 10 total locomotion0.60.71.0-0.90.70.7-0.70.9-0.90.9-0.9-0.91.00.9-0.90.8-0.80.8-0.80.80.3
Short access total locomotion1.51.62.9-1.31.11.1-1.11.3-1.31.3-1.3-1.31.71.3-1.31.2-1.21.2-1.31.30.9
One hour access (0.3 mA shock)0.10.10.80.2-0.5-0.60.6-0.20.2-0.20.20.2-0.1-0.10.1-0.20.2-0.20.2-0.20.9
Compulsive drug intake0.50.52.30.6-0.7-0.60.7-0.60.6-0.60.60.6-0.3-0.60.6-0.60.6-0.60.6-0.61.5
One hour access (shock baseline)0.00.00.4-0.10.0-0.00.00.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.10.1-0.6
Social response proportion0.50.61.30.7-0.7-0.60.6-0.80.8-0.80.90.9-0.3-0.60.6-0.90.9-0.90.6-0.61.1
Social responses0.40.61.00.8-0.3-0.20.2-0.90.9-0.91.01.0-0.5-0.70.7-1.01.0-0.90.7-0.70.2
Social time0.50.70.90.9-0.8-0.70.7-0.90.9-0.90.90.9-0.5-0.90.9-0.80.8-0.80.7-0.70.9
Soleus weight1.02.84.42.0-1.2-1.01.0-2.02.0-2.01.81.8-0.9-1.51.5-1.91.9-1.91.4-1.42.1
Bone: stiffness1.93.04.1-2.01.71.7-1.61.8-1.81.8-1.8-1.82.01.9-1.91.8-1.81.8-1.61.60.1
Tibialis anterior weight0.10.51.20.8-0.7-0.60.6-0.80.8-0.80.70.7-0.2-0.50.5-0.70.7-0.70.6-0.61.1
Time to tail flick, vehicle, before self-admin1.11.11.71.0-0.7-0.60.6-1.31.3-1.31.11.1-0.8-1.21.2-1.21.2-1.21.2-1.2-0.2
Time to tail flick, vehicle, after self-admin2.02.13.8-1.41.31.4-1.41.4-1.41.4-1.4-1.41.91.5-1.51.5-1.51.5-1.41.41.1
Time to tail flick, test, before self-admin0.50.51.30.7-0.6-0.60.6-0.70.7-0.70.60.6-1.0-0.80.8-0.60.6-0.60.7-0.7-1.1
Time to tail flick, test, after self-admin0.70.71.1-1.00.90.9-0.90.7-0.70.7-0.8-0.81.00.9-0.90.7-0.70.7-1.01.00.1
Delta time to tail flick, vehicle, before/after SA0.60.61.1-0.70.30.3-0.30.9-0.90.9-0.8-0.80.80.8-0.80.8-0.80.8-0.80.81.0
Delta time to tail flick, test, before/after SA1.71.52.8-1.31.31.4-1.41.1-1.11.1-1.0-1.01.71.4-1.41.0-1.01.1-1.41.40.9
Tibia length10.629.943.3-5.36.56.6-6.65.2-5.25.2-5.1-5.15.65.2-5.25.2-5.25.2-5.85.8-3.9
Ambulatory time before self-admin1.41.44.3-0.81.61.6-1.61.0-1.01.0-1.0-1.00.90.9-0.91.1-1.11.1-1.01.0-2.1
Ambulatory time after self-admin0.30.30.90.3-0.8-1.01.0-0.30.3-0.30.40.4-0.7-0.30.3-0.40.4-0.40.5-0.40.8
Bone: tissue strength0.30.32.9-0.1-0.9-1.01.00.2-0.20.2-0.1-0.1-0.2-0.10.10.1-0.10.10.3-0.31.7
Total heroin consumption3.84.45.6-2.41.81.6-1.62.3-2.32.3-2.3-2.32.02.3-2.32.3-2.32.3-2.22.2-0.3
Bone: trabecular number0.30.41.20.5-0.7-0.80.8-0.40.4-0.40.50.5-1.0-0.40.4-0.50.5-0.51.1-1.1-0.7
Bone: trabecular spacing0.20.20.8-0.30.60.6-0.60.3-0.30.3-0.3-0.30.60.2-0.20.1-0.10.2-0.90.90.2
Bone: trabecular thickness0.30.31.00.3-0.9-1.01.0-0.30.3-0.30.30.3-0.7-0.20.2-0.20.2-0.21.0-1.0-0.2
Bone: trabecular tissue density0.10.20.40.30.40.5-0.5-0.40.4-0.40.40.40.1-0.40.4-0.40.4-0.4-0.60.6-0.1
Water consumed over 24 hours0.81.01.71.1-0.5-0.40.4-1.31.3-1.31.21.2-1.1-1.01.0-1.21.2-1.20.8-0.8-0.2
Number of responses in last shaping day2.32.43.0-1.51.61.7-1.71.6-1.61.6-1.6-1.61.71.6-1.61.5-1.51.5-1.51.5-0.8