Hub : Genes

Bcdin3d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Bcdin3d 0.08 0.05 5.9e-10 0.08 0.09 0.09 0.09 2.3e-09 4.8e-10 4.1e-10 8.2e-10
2 Liver mRNA stability Bcdin3d 0.04 0.04 4.4e-05 0.03 0.03 0.03 0.03 3.8e-04 1.3e-04 3.1e-04 4.5e-04
3 BLA mRNA stability Bcdin3d 0.1 0.07 1.2e-06 0.09 0.09 0.09 0.05 1.3e-05 1.1e-05 1.8e-05 1.9e-03
4 NAcc mRNA stability Bcdin3d 0.12 0.07 0.0e+00 0.15 0.17 0.17 0.17 1.4e-22 1.2e-25 2.9e-25 1.0e-25
5 OFC mRNA stability Bcdin3d 0.13 0.1 6.0e-03 0.02 0.02 0.01 0.02 1.1e-01 1.0e-01 2.2e-01 9.1e-02
6 Brain mRNA stability Bcdin3d 0.16 0.11 4.3e-15 0.16 0.16 0.16 0.15 1.9e-14 2.7e-14 1.3e-14 3.1e-14
7 Adipose mRNA stability Bcdin3d 0.04 0.04 1.0e-04 0.03 0.02 0.03 0.02 5.2e-04 1.1e-03 5.8e-04 1.1e-03
8 RMTg mRNA stability Bcdin3d 0.31 0.23 9.2e-04 0.11 0.09 0.1 0.11 8.7e-04 2.6e-03 1.6e-03 7.3e-04
9 pVTA mRNA stability Bcdin3d 0.22 0.14 6.9e-11 0.13 0.12 0.12 0.13 8.8e-11 5.0e-10 3.8e-10 1.7e-10
10 IC mRNA stability Bcdin3d 0.12 0.09 1.1e-04 0.06 0.06 0.06 0.06 1.1e-03 1.1e-03 1.9e-03 1.8e-03
11 IL gene expression Bcdin3d 0.47 0.3 1.1e-03 0.09 0.13 0.12 0.09 3.5e-03 6.3e-04 9.2e-04 4.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density8.815.118.2-4.1-4.1-4.0-4.0-3.8-4.1-3.7-4.3-4.0-3.33.4
Area under the delay curve1.01.12.6-1.1-1.0-1.0-1.0-1.2-1.0-1.4-0.9-0.8-1.60.5
BMI with tail6.723.027.2-5.2-5.0-5.0-5.1-5.0-4.9-5.2-4.9-4.6-4.13.3
BMI without tail1.64.86.1-2.5-2.3-2.3-2.3-2.3-2.2-2.4-2.3-2.0-1.81.4
Body weight6.628.932.8-5.7-5.7-5.7-5.7-5.7-5.5-5.7-5.5-5.1-4.73.6
Weight adjusted by age1.72.64.0-1.7-1.5-1.5-1.6-1.2-1.7-1.5-1.9-1.9-0.62.0
Bone surface10.719.622.0-4.7-4.6-4.6-4.6-4.3-4.6-4.3-4.7-4.5-3.83.7
Bone volume8.615.417.6-4.1-4.2-4.2-3.9-4.0-4.0-3.8-4.1-3.9-3.82.9
Breakpoint value in progressive ratio session1.21.42.2-1.2-1.2-1.2-1.3-1.1-1.4-1.0-1.1-1.5-0.51.5
Number of licking bursts0.71.11.71.21.11.11.31.31.01.20.70.81.3-0.2
Context. condit. distance diff. score0.20.20.4-0.3-0.5-0.5-0.4-0.5-0.4-0.4-0.4-0.6-0.40.5
Locomotion velocity, session 11.81.94.31.41.51.51.51.81.11.51.00.92.10.2
Locomotion distance, session 12.53.23.81.91.91.91.91.91.81.81.91.61.9-0.9
Locomotion velocity, session 20.20.20.30.40.50.60.50.60.50.50.40.50.6-0.2
Locomotion distance, session 22.33.24.21.72.02.01.82.01.81.81.71.62.0-0.9
Locomotion velocity, session 34.65.26.22.42.42.42.52.52.42.42.12.12.3-1.4
Locomotion distance, session 34.44.85.82.22.32.22.32.12.42.12.22.31.7-2.1
Stereotopy head waving bouts, day 30.70.92.0-1.0-0.8-0.7-0.8-0.4-1.0-0.7-1.4-1.0-0.11.4
Stereotopy head waving duration, day 30.40.51.6-0.7-0.5-0.5-0.6-0.2-0.8-0.5-1.0-0.80.11.3
Locomotion velocity, session 71.01.13.30.91.11.21.11.40.81.10.30.61.80.4
Locomotion distance, session 72.53.14.91.71.92.01.92.11.71.91.31.62.2-0.7
Stereotopy head waving bouts, day 71.01.11.7-1.2-1.1-1.1-0.9-1.0-1.1-1.0-1.3-1.1-1.00.9
Stereotopy head waving duration, day 71.01.31.5-1.2-1.2-1.2-1.1-1.1-1.1-1.1-1.2-1.1-1.20.7
Locomotion velocity, session 80.10.10.50.40.20.30.30.40.10.30.0-0.10.70.6
Locomotion distance, session 81.11.72.01.41.41.41.31.41.41.31.31.11.3-0.7
Degree of sensitization distance0.30.30.7-0.5-0.4-0.4-0.5-0.3-0.6-0.4-0.7-0.60.00.8
Degree of sensitization stereotypy0.20.20.9-0.4-0.5-0.6-0.3-0.6-0.3-0.5-0.3-0.2-1.0-0.3
Conditioned locomotion0.00.00.10.00.10.10.10.3-0.00.2-0.2-0.20.20.3
Cocaine response after cond. corrected0.00.00.00.10.10.1-0.00.10.1-0.00.00.10.0-0.1
Cocaine response after cond. not corrected0.50.50.70.80.80.70.70.70.80.60.80.90.5-0.8
Cocaine response before conditioning3.23.84.52.12.02.02.11.82.12.02.12.01.5-1.8
Saline control response0.00.00.20.1-0.0-0.0-0.00.1-0.10.1-0.2-0.20.30.5
Bone: connectivity density5.78.911.4-3.1-3.0-3.0-3.0-2.7-3.2-2.8-3.4-3.2-2.23.0
Bone: cortical apparent density0.10.20.20.40.40.40.40.40.40.40.40.40.3-0.4
Bone: cortical area9.214.216.6-4.0-3.9-3.8-3.9-3.5-4.1-3.6-4.1-4.0-3.03.5
Bone: cortical porosity0.30.31.10.60.40.40.50.20.60.40.80.7-0.0-1.1
Bone: cortical porosity0.50.51.40.70.60.60.60.40.80.60.90.90.1-1.2
Bone: cortical thickness3.05.06.4-2.3-2.3-2.3-2.2-2.1-2.5-2.1-2.5-2.4-1.82.2
Bone: cortical thickness0.10.10.4-0.20.10.1-0.10.3-0.2-0.0-0.3-0.10.60.5
Bone: cortical tissue density0.20.20.30.50.50.50.50.50.50.50.50.50.4-0.4
Condit. Reinf. active minus inactive responses0.10.10.20.30.30.30.30.30.20.40.20.20.40.0
Condit. Reinf. active-inactive response ratio0.30.30.5-0.5-0.5-0.5-0.5-0.4-0.7-0.4-0.6-0.6-0.30.7
Condit. Reinf. active responses0.70.81.10.91.01.00.91.00.91.00.80.81.0-0.5
Condit. Reinf. inactive responses2.93.64.12.02.02.01.91.92.01.91.91.91.8-1.5
Incentive salience index mean0.00.00.0-0.0-0.1-0.10.0-0.0-0.10.1-0.1-0.10.00.2
Condit. Reinf. lever presses0.10.20.4-0.4-0.5-0.5-0.4-0.6-0.3-0.4-0.3-0.3-0.6-0.0
Condit. Reinf. active minus inactive responses0.20.31.3-0.1-0.4-0.4-0.2-0.60.0-0.20.10.2-1.2-0.8
Condit. Reinf. active-inactive response ratio0.30.41.90.30.0-0.00.2-0.30.50.00.60.7-1.1-1.4
Condit. Reinf. active responses0.10.20.80.30.20.20.3-0.00.50.20.40.6-0.4-0.9
Condit. Reinf. inactive responses0.60.71.10.80.90.90.90.90.90.90.80.81.0-0.5
Condit. Reinf. lever presses0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.2-0.00.00.1
Condit. Reinf. lever reinforcers received0.30.41.00.70.50.50.70.30.80.60.70.90.0-1.0
Conditioned reinforcement - actives0.91.62.81.21.31.31.31.11.40.91.41.70.8-1.5
Conditioned reinforcement - inactives4.56.67.32.62.72.72.72.72.62.52.72.72.3-2.0
Conditioned locomotion0.20.30.70.60.60.60.80.50.60.70.50.6-0.0-0.3
Patch foraging indifference point 0 sec3.56.49.52.82.72.72.83.02.22.92.12.03.1-0.5
Patch foraging indifference point AUC0.81.21.31.11.11.11.11.11.11.11.11.10.7-1.0
Delay disc. indifference point, 0s delay1.41.62.5-1.3-1.3-1.4-1.3-1.6-1.1-1.3-1.1-1.1-1.30.5
Delay disc. indifference point, 16s delay0.80.91.7-1.0-0.9-0.9-0.9-0.9-1.0-1.1-0.8-0.8-1.30.5
Delay disc. indifference point, 2s delay1.71.93.3-1.4-1.4-1.4-1.3-1.5-1.3-1.7-1.3-1.2-1.80.7
Delay disc. indifference point, 24s delay0.80.91.2-1.0-0.9-0.9-0.9-0.7-1.1-0.9-1.0-1.1-1.11.0
Delay disc. indifference point, 4s delay0.90.92.9-1.0-0.9-0.9-0.8-1.2-0.7-1.2-0.7-0.6-1.70.0
Delay disc. indifference point, 8s delay1.61.92.5-1.5-1.4-1.3-1.3-1.4-1.4-1.6-1.4-1.4-1.31.2
Indifference point function ln k3.45.97.4-2.5-2.6-2.6-2.5-2.7-2.4-2.5-2.3-2.3-2.51.4
Indifference point function log k3.45.97.4-2.5-2.6-2.6-2.5-2.7-2.4-2.5-2.3-2.3-2.51.4
Patch foraging total patch changes 0 sec3.36.18.62.72.62.72.72.92.22.82.12.02.9-0.5
Patch foraging total patch changes 12 sec4.25.48.32.42.52.62.52.92.12.62.01.82.7-0.6
Patch foraging total patch changes 18 sec4.77.29.72.92.92.92.93.02.63.12.42.32.8-1.2
Patch foraging total patch changes 24 sec2.64.56.12.32.32.32.32.52.02.51.81.82.3-0.8
Patch foraging total patch changes 6 sec4.46.79.92.82.82.82.93.12.32.92.12.13.1-0.6
Patch foraging time to switch 0 sec1.83.74.62.02.02.11.92.11.92.01.91.72.1-1.2
Patch foraging water rate 0 sec2.55.36.2-2.5-2.5-2.5-2.3-2.5-2.3-2.3-2.3-2.1-2.51.3
Patch foraging water rate 12 sec2.45.16.3-2.5-2.3-2.3-2.4-2.2-2.3-2.2-2.4-2.3-1.91.8
Patch foraging water rate 18 sec0.30.50.8-0.8-0.7-0.7-0.7-0.7-0.6-0.9-0.7-0.5-0.90.3
Patch foraging water rate 24 sec3.95.47.1-2.5-2.5-2.5-2.5-2.6-2.2-2.7-2.2-2.0-2.41.1
Patch foraging water rate 6 sec4.76.99.0-2.8-2.8-2.9-2.7-2.9-2.5-2.8-2.5-2.3-3.01.3
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.4-0.5-0.5-0.4-0.6-0.3-0.4-0.3-0.2-0.3-0.0
Distance traveled before self-admin1.11.52.11.41.31.41.51.41.11.31.01.01.3-0.1
Distance traveled after self-admin0.60.71.60.90.90.91.01.00.71.10.40.51.20.2
Extensor digitorum longus weight4.116.320.2-4.2-4.3-4.3-4.4-4.5-3.9-4.3-3.6-3.8-4.22.2
Bone: elastic displacement4.45.17.52.42.42.42.32.52.12.32.21.92.7-0.9
Bone: elastic work0.10.10.4-0.1-0.2-0.2-0.3-0.0-0.3-0.1-0.2-0.40.20.7
Bone: endosteal estimation8.117.720.7-4.6-4.4-4.4-4.5-4.1-4.4-4.2-4.3-4.3-3.73.3
Bone: endosteal perimeter6.914.717.5-4.2-4.1-4.1-4.1-3.9-4.0-3.8-3.8-3.8-3.62.7
Epididymis fat weight0.72.43.9-1.7-1.5-1.5-1.6-1.3-1.7-1.4-2.0-1.7-0.31.8
Delta time in closed arm before/after self-admin0.00.00.30.00.00.00.10.00.00.50.20.10.1-0.1
Delta time in open arm before/after self-admin1.01.01.41.21.11.11.00.91.20.81.11.00.8-0.7
Diff in mean of infusions in LGA sessions1.01.21.5-1.2-1.1-1.1-1.1-0.8-1.2-1.1-1.1-1.2-1.01.1
Delay discount exponential model param1.01.12.81.01.01.00.91.10.91.30.80.81.7-0.4
Extinction: sum of active levers before priming1.82.02.8-1.4-1.6-1.6-1.5-1.7-1.5-1.6-1.3-1.4-0.81.0
Active lever presses in extinction session 60.80.82.1-0.8-0.8-0.8-0.8-0.6-1.1-0.6-1.0-1.1-0.11.5
Bone: final force11.618.620.7-4.5-4.5-4.5-4.5-4.5-4.4-4.4-4.2-4.3-4.23.1
Bone: final moment12.920.723.1-4.7-4.8-4.8-4.8-4.7-4.6-4.6-4.4-4.5-4.53.2
Food consumed during 24 hour testing period1.31.82.3-1.3-1.5-1.5-1.3-1.3-1.4-1.2-1.5-1.4-1.41.1
Glucose0.10.21.2-0.00.10.20.10.5-0.20.2-0.3-0.40.71.1
Heart weight0.10.10.3-0.5-0.4-0.4-0.4-0.4-0.3-0.6-0.4-0.3-0.30.0
Delay discount hyperbolic model param1.01.12.71.11.01.00.91.10.91.30.90.81.6-0.4
Intermittent access intake day 1-15 change0.10.11.10.10.10.1-0.0-0.10.3-0.20.30.4-0.1-1.0
Intermittent access intake escalation0.10.20.9-0.2-0.2-0.3-0.4-0.50.0-0.50.00.1-0.4-0.9
Intermittent access intake escalation 20.20.21.20.20.20.20.1-0.00.4-0.10.40.60.1-1.1
Intermitt. access day 1 inactive lever presses0.20.61.60.80.60.60.60.40.90.61.30.8-0.1-1.0
Intermitt. access day 15 inactive lever presses0.51.03.60.80.70.70.80.31.10.61.31.30.1-1.9
Intermitt. access escalation Index0.30.41.1-0.5-0.6-0.6-0.5-0.4-0.8-0.6-0.8-0.8-0.11.1
Intermittent access day 1 total infusions1.01.72.11.41.41.41.41.51.41.41.31.20.6-0.8
Intermittent access day 15 total infusions0.81.21.81.11.21.11.11.11.31.01.21.20.5-1.3
Intermittent access terminal intake (last 3 days)1.31.72.41.31.31.31.21.21.51.21.41.40.6-1.5
Intermittent access total infusions2.02.43.01.61.61.61.51.61.71.41.71.60.8-1.6
Intermittent access day 1 locomotion0.30.40.80.70.70.70.70.90.50.80.50.30.10.3
Intermittent access day 15 total locomotion0.20.40.60.70.80.80.70.80.70.80.50.5-0.1-0.3
Intermittent access total locomotion1.72.12.91.61.61.61.61.71.51.71.41.30.8-0.7
Intermittent access standard deviation0.20.41.10.60.60.60.40.40.70.20.90.60.4-1.0
Left kidney weight1.04.56.0-2.5-2.3-2.3-2.4-2.4-2.0-2.4-2.1-1.8-2.00.6
Right kidney weight4.319.423.7-4.9-4.6-4.6-4.7-4.5-4.5-4.8-4.5-4.2-3.72.8
Cocaine induced anxiety2.43.54.6-2.0-2.0-1.9-2.0-1.9-2.0-2.1-2.0-1.8-1.31.5
Post-drug Anxiety3.33.55.2-2.0-2.0-2.0-2.0-2.0-2.0-2.3-1.9-1.6-1.31.2
Baseline Anxiety0.10.10.2-0.2-0.4-0.4-0.3-0.4-0.2-0.3-0.1-0.2-0.3-0.2
Tail length0.00.00.10.10.10.10.10.10.10.3-0.1-0.00.10.0
Length with tail1.56.37.3-2.6-2.7-2.7-2.7-2.6-2.6-2.6-2.6-2.6-2.21.8
Length without tail5.618.020.5-4.3-4.5-4.5-4.4-4.5-4.3-4.5-4.2-4.2-4.03.0
Times rat made contact with spout0.10.10.30.50.30.30.30.20.30.40.40.40.0-0.4
Lifetime Intake2.73.34.01.92.02.01.91.92.01.81.91.90.9-1.7
Liver weight, left9.916.318.1-4.3-4.3-4.3-4.2-4.2-4.1-4.2-4.1-4.0-3.92.7
Liver weight, right2.95.06.0-2.4-2.4-2.4-2.4-2.4-2.3-2.4-2.3-2.2-1.81.4
Locomotor activity1.62.43.01.61.61.61.71.61.61.41.41.61.7-1.1
Locomotor testing distance3.35.96.92.52.62.62.62.52.52.42.22.52.6-1.7
Locomotor testing rearing2.14.24.92.22.22.22.12.02.21.91.92.12.1-1.7
Locomotion in novel chamber2.43.06.0-1.7-1.9-1.9-1.8-2.2-1.4-2.0-1.2-1.2-2.40.0
Locomotion in novel chamber post-restriction0.10.10.4-0.1-0.1-0.2-0.1-0.30.1-0.30.10.2-0.4-0.7
Fecal boli incidents, locomotor time 11.42.02.81.51.51.41.61.21.51.21.71.60.6-1.4
Change in fecal boli incidents, locomotor task0.70.71.5-0.7-0.7-0.7-0.8-0.7-0.9-0.6-0.9-1.0-0.21.2
Time >=10cm from walls, locomotor time 10.10.10.60.10.20.20.30.6-0.20.1-0.2-0.20.60.8
Bouts of movement, locomotor time 10.00.00.10.10.00.0-0.00.0-0.10.10.2-0.10.30.2
Total resting periods, locomotor time 10.30.41.00.60.60.60.60.60.40.80.60.41.0-0.0
Rest time, locomotor task time 10.60.71.60.80.80.80.90.90.61.20.70.61.3-0.1
Distance moved, locomotor task time 10.00.00.1-0.2-0.1-0.1-0.10.1-0.10.1-0.4-0.3-0.30.3
Vertical activity count, locomotor time 10.51.31.6-1.2-1.2-1.2-1.2-1.1-1.1-1.3-1.3-1.1-1.10.9
Time >=10cm from walls, locomotor time 20.50.81.10.90.90.90.80.91.10.51.00.80.7-0.9
Bouts of movement, locomotor time 22.13.44.5-1.8-2.0-2.0-1.9-2.1-1.9-1.7-1.7-1.7-2.01.2
Total resting periods, locomotor time 22.13.85.1-1.9-2.1-2.1-2.0-2.3-2.0-1.8-1.8-1.8-2.01.2
Rest time, locomotor task time 20.10.20.90.20.20.30.30.3-0.00.6-0.00.00.90.4
Distance moved, locomotor task time 20.00.00.20.10.20.20.10.40.3-0.00.20.1-0.1-0.2
Vertical activity count, locomotor time 20.10.10.3-0.3-0.2-0.2-0.3-0.2-0.0-0.5-0.10.0-0.6-0.3
Light reinforcement 11.84.55.92.22.12.02.11.82.32.02.42.41.3-2.4
Light reinforcement 20.60.92.80.90.70.60.80.41.10.71.11.1-0.4-1.7
Bone: marrow area7.817.019.9-4.5-4.3-4.3-4.4-4.0-4.3-4.1-4.2-4.2-3.63.3
Bone: maximum diameter3.05.57.1-2.7-2.4-2.3-2.5-2.0-2.6-2.2-2.6-2.5-1.62.3
Bone: maximum force16.529.232.7-5.7-5.7-5.7-5.7-5.4-5.6-5.4-5.4-5.5-5.04.2
Bone: maximum moment18.031.635.4-5.9-5.9-5.9-6.0-5.7-5.8-5.6-5.6-5.7-5.24.3
Mean time between licks in bursts0.00.10.20.30.30.30.30.30.40.20.30.30.4-0.2
Mean num. licks in bursts0.20.31.0-0.4-0.5-0.5-0.7-0.7-0.4-0.5-0.1-0.2-1.0-0.3
Cd content in liver0.50.60.70.80.80.80.80.70.80.80.90.80.6-0.8
Co content in liver0.30.40.50.50.70.70.50.70.60.60.60.70.4-0.6
Cu content in liver0.80.92.5-0.8-0.8-0.8-0.9-0.6-1.1-0.7-1.1-1.2-0.11.6
Fe content in liver1.92.32.81.51.61.61.61.51.71.51.61.51.3-1.2
K content in liver0.10.10.40.10.20.3-0.00.30.00.10.1-0.10.60.5
Mg content in liver0.20.20.30.50.50.50.40.50.50.50.40.40.5-0.2
Mn content in liver0.00.00.1-0.00.10.1-0.10.1-0.0-0.0-0.0-0.10.30.4
Na content in liver0.00.00.10.20.10.1-0.0-0.00.2-0.00.30.10.0-0.2
Rb content in liver0.60.71.90.80.70.80.81.10.41.00.30.11.40.9
Se content in liver2.53.04.81.61.91.91.92.01.71.81.31.52.2-0.6
Sr content in liver1.10.91.3-0.9-1.0-1.0-0.9-0.9-1.1-0.8-1.2-1.1-0.71.1
Zn content in liver1.11.21.51.21.11.21.11.11.11.11.11.11.1-0.7
Bone: minimum diameter9.216.818.7-4.3-4.3-4.3-4.3-4.1-4.3-4.0-4.2-4.2-3.73.2
Time in familiar zone, hab. session 10.10.10.40.50.20.20.30.10.40.30.50.4-0.2-0.6
Time in novel zone, hab. session 10.10.10.3-0.4-0.3-0.3-0.3-0.2-0.4-0.3-0.5-0.4-0.00.6
Total zone transitions, hab. session 10.20.30.60.60.60.50.50.40.70.40.80.70.2-0.8
Total locomotion distance, hab. session 10.10.10.50.00.20.20.10.4-0.00.2-0.2-0.20.70.7
Locomotion velocity, hab. session 10.10.10.6-0.10.10.1-0.00.3-0.10.1-0.3-0.30.50.7
Time in familiar zone, hab. session 20.80.91.8-0.8-1.0-1.0-1.0-1.2-0.8-0.9-0.5-0.7-1.30.1
Time in novel zone, hab. session 20.80.82.00.80.91.01.01.20.60.90.40.51.40.3
Total zone transitions, hab. session 20.30.30.50.60.60.60.60.60.70.60.70.50.5-0.4
Total locomotion distance, hab. session 20.10.20.50.30.40.50.40.60.40.50.10.20.70.3
Locomotion velocity, hab. session 20.10.10.30.20.30.30.30.40.20.4-0.00.00.50.3
Novel to familiar place preference ratio1.51.72.0-1.2-1.4-1.4-1.2-1.3-1.4-1.1-1.4-1.4-1.21.2
Novelty place preference1.01.11.5-0.9-1.1-1.1-0.9-1.0-1.2-0.9-1.1-1.2-0.91.2
Time in novel zone, NPP test0.80.91.4-0.8-1.0-1.0-0.8-0.9-1.1-0.7-1.0-1.1-0.71.2
Total zone transitions, NPP test1.82.64.01.71.71.81.71.91.61.71.41.32.0-0.4
Total locomotion distance, NPP test2.23.05.01.81.91.91.92.11.71.91.31.42.2-0.4
Locomotion velocity, NPP test1.31.93.41.41.51.51.51.71.31.50.91.11.8-0.1
Intraocular pressure6.89.711.53.23.23.23.43.13.23.23.03.32.8-2.6
Delta distance traveled before/after self-admin0.00.00.0-0.1-0.1-0.1-0.1-0.00.00.1-0.1-0.10.1-0.1
Delta ambulatory time before/after self-admin0.10.10.30.10.20.20.10.30.20.30.10.20.5-0.4
Parametrial fat weight0.92.13.11.51.51.51.41.41.61.21.51.80.8-1.7
Pavlov. Cond. lever latency0.20.31.8-0.1-0.3-0.2-0.20.1-0.6-0.1-0.5-0.70.31.3
Pavlov. Cond. magazine entry latency0.30.31.1-0.4-0.4-0.4-0.5-0.7-0.0-0.50.20.2-1.0-1.0
Pavlov. Cond. change in total contacts0.40.41.3-0.6-0.5-0.5-0.6-0.8-0.1-0.60.00.1-1.2-1.0
Pavlov. Cond. index score0.20.31.0-0.5-0.3-0.4-0.5-0.6-0.0-0.50.00.2-0.9-1.0
Pavlov. Cond. latency score0.20.21.1-0.4-0.2-0.3-0.3-0.50.1-0.40.10.3-0.8-1.1
Pavlov. Cond. lever contacts0.50.62.80.40.50.40.40.10.90.30.91.0-0.3-1.7
Pavlov. Cond. magazine entry number0.10.20.60.30.20.30.40.4-0.00.4-0.1-0.20.70.8
Pavlov. Cond. intertrial magazine entries1.61.95.91.21.41.51.31.90.81.50.60.52.41.0
Pavlov. Cond. lever-magazine prob. diff.0.40.41.1-0.7-0.6-0.6-0.7-0.9-0.3-0.8-0.2-0.1-1.1-0.7
Pavlov. Cond. response bias0.20.21.3-0.00.10.1-0.0-0.20.4-0.10.50.5-0.5-1.1
Pavlov. Cond. lever latency0.40.51.3-0.7-0.7-0.8-0.8-1.0-0.5-0.8-0.3-0.5-1.1-0.2
Pavlov. Cond. magazine entry latency0.70.83.7-0.7-0.6-0.5-0.6-0.0-1.0-0.4-1.1-1.10.41.9
Pavlov. Cond. change in total contacts0.91.42.2-1.1-1.2-1.2-1.0-1.0-1.3-1.0-1.5-1.4-0.81.5
Pavlov. Cond. index score0.40.52.9-0.4-0.3-0.2-0.30.2-0.7-0.1-0.9-0.90.61.7
Pavlov. Cond. latency score0.40.52.7-0.3-0.2-0.2-0.20.3-0.6-0.0-0.8-0.80.71.6
Pavlov. Cond. lever contacts0.20.31.00.50.60.60.60.80.30.60.20.31.00.4
Pavlov. Cond. magazine entry number1.51.85.91.21.11.01.10.51.50.81.71.7-0.0-2.4
Pavlov. Cond. intertrial magazine entries4.77.19.02.82.72.62.62.32.92.43.03.01.8-3.0
Pavlov. Cond. lever-magazine prob. diff.0.50.73.3-0.5-0.5-0.4-0.40.0-0.9-0.3-1.1-1.00.51.8
Pavlov. Cond. response bias0.10.10.60.10.10.20.20.4-0.10.2-0.2-0.20.60.8
Time in closed arm before self-admin2.02.63.4-1.7-1.7-1.6-1.7-1.4-1.7-1.8-1.7-1.6-1.41.5
Time in closed arm after self-admin0.20.20.3-0.5-0.5-0.5-0.5-0.3-0.5-0.2-0.3-0.3-0.40.2
Time in open arm before self-admin0.10.20.40.40.40.40.40.50.10.60.10.10.60.2
Time in open arm after self-admin0.10.10.30.40.30.30.20.20.20.10.2-0.00.60.2
Bone: periosteal estimation11.925.129.0-5.4-5.2-5.2-5.3-4.9-5.3-4.9-5.2-5.1-4.34.2
Bone: periosteal perimeter10.417.920.5-4.5-4.4-4.4-4.5-4.1-4.4-4.2-4.3-4.3-3.83.3
Bone: post-yield work9.113.315.6-4.0-3.8-3.7-3.9-3.6-3.8-3.7-3.7-3.8-3.13.0
Progressive ratio test 1 active lever presses6.78.310.03.13.13.13.03.23.03.12.82.72.4-1.9
Progressive ratio test 1 breakpoint6.47.89.53.03.03.02.93.12.93.02.72.62.3-1.8
Progressive ratio test 1 inactive lever presses1.72.54.51.61.51.41.41.11.81.22.02.00.3-2.1
Progressive ratio test 2 active lever presses2.02.32.91.61.71.71.61.61.71.21.51.70.8-1.6
Progressive ratio test 2 breakpoint1.92.22.71.51.61.61.51.51.61.21.51.60.7-1.5
Progressive ratio test 2 inactive lever presses1.11.83.11.41.31.31.31.11.51.01.51.60.7-1.8
Incentive Sensitization - Responses0.30.41.0-0.6-0.5-0.6-0.6-0.7-0.3-0.9-0.5-0.2-1.0-0.4
Incentive Sensitization - Breakpoint0.20.30.8-0.5-0.4-0.5-0.5-0.5-0.2-0.8-0.4-0.1-0.9-0.5
Sum of active levers in priming session hrs 5-60.10.10.50.0-0.00.00.10.1-0.20.5-0.1-0.40.60.7
Progressive ratio0.60.92.00.91.01.11.01.30.80.90.40.71.40.1
Food seeking constrained by brief footshock1.51.83.11.51.51.51.51.61.21.31.11.11.8-0.2
Seeking ratio, punishment vs. effort0.00.00.10.1-0.1-0.1-0.1-0.2-0.0-0.10.2-0.0-0.2-0.2
Retroperitoneal fat weight0.52.04.51.21.51.61.41.81.21.41.11.22.1-0.4
Reaction time number correct1.12.22.6-1.6-1.5-1.5-1.5-1.5-1.5-1.5-1.6-1.5-1.21.3
Reaction time mean minus median4.310.612.33.43.33.33.43.13.43.43.43.52.5-2.8
Reaction time mean minus median AUC2.87.28.42.82.82.82.82.62.82.82.82.92.1-2.2
Reaction time num false alarms1.52.22.81.51.51.51.71.51.51.71.41.41.5-1.1
Reaction time num false alarms AUC1.92.93.51.71.71.71.91.71.81.81.71.71.6-1.4
Reaction time trials correct on left1.12.22.6-1.6-1.5-1.5-1.5-1.5-1.5-1.5-1.6-1.5-1.21.3
Reaction time trials on left0.91.72.0-1.4-1.3-1.3-1.4-1.3-1.3-1.3-1.4-1.3-1.01.2
Reaction time mean0.71.21.41.11.11.11.21.01.11.11.01.11.0-0.8
Reaction time mean AUC0.40.70.90.90.90.80.90.80.90.90.80.80.8-0.6
Median of all reaction times0.00.00.10.10.10.10.10.00.10.1-0.10.00.30.1
Reaction time omissions9.213.415.13.83.93.93.83.73.83.53.73.93.4-3.0
Reaction time false alarm rate2.53.44.01.91.91.92.01.81.92.01.91.91.7-1.6
Reaction time premature initiation rate5.47.59.72.72.82.82.72.52.92.43.03.12.4-2.8
Reaction time premature initiations1.83.34.71.71.81.81.71.52.01.42.02.21.6-2.0
Std. dev. reaction times4.88.810.03.13.13.13.22.93.13.13.03.12.6-2.3
Reaction time trials completed0.91.72.0-1.4-1.3-1.3-1.4-1.3-1.3-1.3-1.4-1.3-1.01.2
Reaction time trials AUC1.52.83.3-1.8-1.7-1.7-1.7-1.7-1.7-1.7-1.8-1.7-1.41.5
Run reversals in cocaine runway, females0.20.20.7-0.4-0.5-0.5-0.6-0.6-0.2-0.5-0.1-0.3-0.8-0.3
Run reversals in cocaine runway, males1.01.01.31.01.01.01.00.81.11.11.11.10.5-1.1
Latency to leave start box in cocaine runway0.00.00.10.00.20.20.10.20.10.10.20.20.1-0.2
Latency to leave start box in cocaine runway, F1.01.11.41.01.21.21.11.11.10.91.11.20.8-0.9
Latency to leave start box in cocaine runway, M1.71.61.8-1.3-1.4-1.4-1.4-1.3-1.3-1.2-1.3-1.3-1.00.9
Std. dev. time between licks in bursts1.21.62.11.31.31.31.51.41.31.41.01.31.3-0.9
Total sessions with >9 infusions2.83.44.01.92.02.01.91.92.01.91.82.00.9-1.7
Short access day 1 total inactive lever presses1.92.53.01.71.71.71.61.61.71.61.71.60.8-1.5
Short access day 10 total inactive lever presses0.00.10.30.30.0-0.00.1-0.20.30.40.60.3-0.0-0.4
Short access day 1 total infusions1.01.31.91.21.31.31.21.41.21.21.01.20.6-0.7
Short access day 10 total infusions2.02.63.61.71.71.71.61.71.81.91.71.50.6-1.3
Short access total infusions3.44.35.42.22.32.32.22.32.22.22.02.11.2-1.5
Short access day 1 locomotion0.40.50.70.70.70.70.70.70.70.80.60.7-0.6-0.4
Short access day 10 total locomotion0.20.30.50.70.60.60.60.60.60.60.70.50.0-0.3
Short access total locomotion1.01.31.71.31.21.21.21.11.31.31.21.10.1-0.8
One hour access (0.3 mA shock)0.30.31.80.10.20.10.1-0.10.5-0.10.50.6-0.8-1.3
Compulsive drug intake0.10.10.5-0.3-0.3-0.3-0.4-0.4-0.1-0.20.0-0.1-0.7-0.4
One hour access (shock baseline)0.10.10.7-0.1-0.0-0.1-0.0-0.20.2-0.30.10.4-0.6-0.8
Social response proportion0.20.30.40.60.50.50.50.60.50.50.40.60.4-0.4
Social responses7.49.610.93.33.23.13.12.93.23.03.23.32.8-2.8
Social time0.10.20.6-0.3-0.4-0.4-0.5-0.6-0.2-0.80.0-0.1-0.2-0.2
Soleus weight0.82.33.0-1.6-1.6-1.6-1.7-1.7-1.4-1.5-1.2-1.5-1.70.8
Bone: stiffness19.531.735.6-6.0-6.0-6.0-6.0-5.8-5.7-5.7-5.6-5.5-5.63.8
Tibialis anterior weight1.44.89.6-2.1-2.3-2.4-2.5-2.8-1.7-2.5-1.3-1.5-3.1-0.2
Time to tail flick, vehicle, before self-admin1.61.74.31.31.21.21.21.21.11.11.41.32.1-0.9
Time to tail flick, vehicle, after self-admin0.20.30.6-0.6-0.5-0.5-0.7-0.6-0.3-0.8-0.3-0.4-0.7-0.0
Time to tail flick, test, before self-admin0.20.20.60.50.40.40.20.40.40.00.50.20.8-0.2
Time to tail flick, test, after self-admin1.01.01.7-1.0-1.1-1.1-1.1-1.3-1.0-1.2-0.8-0.9-1.00.4
Delta time to tail flick, vehicle, before/after SA0.70.71.9-0.9-0.7-0.7-0.8-0.8-0.6-0.7-0.8-0.7-1.40.4
Delta time to tail flick, test, before/after SA0.40.41.1-0.6-0.6-0.6-0.5-0.9-0.5-0.3-0.5-0.2-1.00.0
Tibia length6.217.220.8-4.3-4.3-4.3-4.2-4.0-4.4-3.9-4.6-4.5-3.23.9
Ambulatory time before self-admin1.82.73.81.91.81.81.91.71.71.71.61.61.4-0.7
Ambulatory time after self-admin1.61.92.91.51.41.41.51.51.41.71.21.21.5-0.7
Bone: tissue strength1.61.61.9-1.2-1.3-1.4-1.4-1.3-1.3-1.3-1.1-1.4-1.31.0
Total heroin consumption0.80.91.5-0.9-1.0-1.0-1.0-0.8-1.0-0.8-1.0-1.2-0.61.1
Bone: trabecular number5.59.111.8-3.2-3.1-3.1-3.0-2.8-3.2-2.8-3.4-3.2-2.42.9
Bone: trabecular spacing2.22.93.71.81.71.71.71.51.91.61.91.91.2-1.8
Bone: trabecular thickness0.20.20.90.0-0.2-0.20.0-0.40.2-0.20.20.3-0.8-1.0
Bone: trabecular tissue density0.20.31.7-0.1-0.5-0.5-0.2-0.8-0.0-0.20.00.0-1.3-0.9
Water consumed over 24 hours0.10.10.3-0.0-0.2-0.2-0.1-0.1-0.30.1-0.4-0.4-0.10.5
Number of responses in last shaping day0.20.20.60.40.20.20.20.00.40.30.30.4-0.8-0.7