Bcam

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	Bcam	0.15	0.07	0.0e+00	0.18	0.18	0.19	0.19	5.6e-26	6.0e-27	1.0e-27	1.7e-27
2	BLA	gene expression	Bcam	0.22	0.12	1.8e-10	0.13	0.15	0.16	0.17	2.5e-07	2.0e-08	1.4e-08	3.4e-09
3	pVTA	gene expression	Bcam	0.13	0.08	1.6e-08	0.07	0.07	0.03	0.07	5.3e-06	3.9e-06	2.8e-03	4.0e-06
4	Brain	gene expression	Bcam	0.42	0.13	0.0e+00	0.48	0.5	0.5	0.5	1.6e-50	7.0e-53	1.1e-52	1.1e-52
5	PL	gene expression	Bcam	0.23	0.09	0.0e+00	0.33	0.35	0.34	0.35	1.8e-37	4.7e-40	7.1e-39	1.0e-39
6	Adipose	gene expression	Bcam	0.38	0.23	0.0e+00	0.22	0.23	0.23	0.22	1.2e-23	8.4e-25	8.7e-25	3.8e-24
7	IC	gene expression	Bcam	0.28	0.13	1.2e-09	0.18	0.14	0.13	0.16	7.5e-08	1.4e-06	2.9e-06	4.2e-07
8	Liver	gene expression	Bcam	0.07	0.05	9.9e-08	0.07	0.06	0.06	0.07	1.3e-08	3.7e-07	2.9e-07	4.9e-08
9	IL	gene expression	Bcam	0.47	0.14	5.1e-10	0.29	0.23	0.33	0.31	1.0e-07	2.6e-06	1.3e-08	3.0e-08
10	OFC	gene expression	Bcam	0.45	0.2	2.8e-07	0.26	0.21	0.25	0.26	9.1e-07	8.1e-06	1.4e-06	7.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.1	0.1	0.3	-0.1	0.5	0.3	0.3	0.2	0.3	-0.5	-0.4	-0.3	0.4
Area under the delay curve	1.7	2.6	4.0	1.5	-1.1	-1.4	-1.3	-1.5	-1.6	1.7	2.0	2.0	-1.7
BMI with tail	0.7	2.4	3.0	-1.7	1.6	1.7	1.7	1.6	1.5	-1.7	-1.5	-1.4	0.8
BMI without tail	0.3	1.5	2.2	-1.5	1.3	1.4	1.4	1.3	1.2	-1.0	-1.0	-1.0	0.9
Body weight	1.2	5.3	6.7	-2.5	2.4	2.5	2.5	2.3	2.2	-2.6	-2.4	-2.3	1.1
Weight adjusted by age	0.0	0.0	0.0	0.0	-0.2	-0.1	-0.0	0.0	-0.0	-0.2	-0.1	-0.1	-0.1
Bone surface	0.4	0.9	1.2	-0.9	1.1	1.0	1.0	0.8	0.9	-1.1	-1.0	-0.9	0.5
Bone volume	0.3	0.6	1.1	-0.7	1.1	0.7	0.8	0.7	0.7	-1.0	-1.0	-0.8	0.1
Breakpoint value in progressive ratio session	1.4	2.5	3.0	1.5	-1.3	-1.7	-1.5	-1.7	-1.7	1.5	1.6	1.6	-1.4
Number of licking bursts	0.7	2.2	4.4	-2.1	1.8	1.3	1.5	1.6	1.3	-1.5	-1.5	-1.3	0.3
Context. condit. distance diff. score	0.2	0.2	0.4	-0.5	0.7	0.5	0.5	0.4	0.4	-0.4	-0.5	-0.5	-0.3
Locomotion velocity, session 1	0.1	0.1	0.7	0.2	-0.2	-0.2	-0.2	-0.3	-0.3	-0.4	-0.1	-0.0	-0.8
Locomotion distance, session 1	0.2	0.2	0.6	-0.3	0.3	0.3	0.4	0.3	0.3	-0.7	-0.7	-0.6	0.4
Locomotion velocity, session 2	0.6	0.8	1.2	-1.0	0.8	0.7	0.8	1.0	0.9	-1.1	-0.8	-0.9	0.6
Locomotion distance, session 2	0.4	0.5	0.9	-0.6	0.4	0.5	0.7	0.7	0.7	-0.9	-0.9	-0.8	0.9
Locomotion velocity, session 3	0.1	0.1	0.2	-0.4	0.4	0.4	0.3	0.4	0.5	-0.3	-0.3	-0.3	0.4
Locomotion distance, session 3	0.7	0.8	1.8	1.1	-1.3	-1.1	-1.1	-0.9	-0.7	0.9	0.8	0.7	0.1
Stereotopy head waving bouts, day 3	0.6	0.7	2.9	-1.0	0.6	0.8	0.6	0.9	0.9	-0.4	-0.3	-0.4	1.7
Stereotopy head waving duration, day 3	0.9	1.1	1.7	-1.3	1.2	1.1	1.1	1.1	1.1	-0.6	-0.7	-0.6	1.2
Locomotion velocity, session 7	0.1	0.1	0.2	0.3	-0.2	-0.3	-0.1	-0.2	-0.1	0.4	0.0	0.0	0.5
Locomotion distance, session 7	0.1	0.2	0.4	-0.3	0.5	0.3	0.4	0.3	0.3	-0.6	-0.5	-0.4	0.0
Stereotopy head waving bouts, day 7	0.9	1.1	1.7	-1.1	0.9	1.1	0.9	1.0	1.1	-0.7	-1.0	-1.1	1.3
Stereotopy head waving duration, day 7	0.6	0.7	1.0	-1.0	0.9	1.0	0.8	0.9	0.9	-0.6	-0.8	-0.8	0.7
Locomotion velocity, session 8	0.1	0.1	0.3	0.1	-0.4	-0.3	-0.4	-0.2	-0.2	0.6	0.6	0.4	-0.2
Locomotion distance, session 8	0.1	0.1	0.4	-0.3	0.3	0.2	0.3	0.2	0.3	-0.6	-0.5	-0.5	0.0
Degree of sensitization distance	0.8	0.9	2.0	-1.1	1.4	1.1	1.2	0.8	0.7	-1.0	-0.8	-0.7	-0.2
Degree of sensitization stereotypy	1.0	1.1	1.3	-1.1	1.0	1.1	1.0	1.0	1.1	-0.8	-1.1	-1.2	1.0
Conditioned locomotion	0.2	0.3	1.4	0.2	-0.7	-0.5	-0.5	-0.2	0.0	0.4	0.1	-0.0	1.2
Cocaine response after cond. corrected	0.7	1.0	1.3	-1.0	0.8	0.9	0.9	1.0	1.1	-1.1	-1.1	-1.2	1.1
Cocaine response after cond. not corrected	1.7	2.5	3.7	-1.5	1.2	1.4	1.3	1.5	1.7	-1.7	-1.7	-1.8	1.9
Cocaine response before conditioning	1.4	1.7	2.4	-1.4	1.1	1.3	1.2	1.4	1.5	-1.3	-1.2	-1.4	1.5
Saline control response	1.6	2.2	2.8	-1.7	1.6	1.6	1.6	1.6	1.5	-1.3	-1.4	-1.3	1.3
Bone: connectivity density	0.0	0.0	0.3	0.1	0.2	0.2	0.1	0.0	0.1	-0.1	-0.1	-0.1	0.5
Bone: cortical apparent density	0.1	0.1	0.3	0.3	0.0	-0.3	-0.2	-0.3	-0.4	0.5	0.3	0.3	-0.4
Bone: cortical area	1.2	2.0	2.7	-1.6	1.6	1.4	1.5	1.5	1.3	-1.4	-1.5	-1.4	0.6
Bone: cortical porosity	0.6	0.7	2.0	0.8	-1.4	-0.9	-1.1	-0.6	-0.4	0.3	0.6	0.3	0.9
Bone: cortical porosity	0.3	0.3	1.4	0.4	-0.9	-0.5	-0.7	-0.2	-0.0	0.1	0.3	0.0	1.2
Bone: cortical thickness	0.4	0.7	1.1	-1.0	1.0	0.8	0.9	0.9	0.8	-0.7	-0.9	-0.8	0.7
Bone: cortical thickness	1.5	1.8	2.6	-1.4	1.3	1.3	1.3	1.3	1.3	-1.6	-1.4	-1.3	1.2
Bone: cortical tissue density	0.1	0.2	0.4	0.4	-0.1	-0.4	-0.3	-0.4	-0.5	0.6	0.4	0.4	-0.4
Condit. Reinf. active minus inactive responses	0.5	0.6	0.8	-0.7	0.9	0.8	0.8	0.8	0.8	-0.8	-0.8	-0.8	0.5
Condit. Reinf. active-inactive response ratio	0.6	0.7	1.0	-0.6	1.0	0.9	0.9	0.8	0.9	-0.8	-0.8	-0.8	0.4
Condit. Reinf. active responses	0.4	0.5	0.7	-0.7	0.8	0.7	0.7	0.7	0.7	-0.8	-0.7	-0.7	0.5
Condit. Reinf. inactive responses	0.0	0.0	0.0	-0.0	0.0	0.1	0.0	-0.0	0.0	-0.1	-0.1	-0.1	0.2
Incentive salience index mean	0.3	0.4	0.9	-0.5	0.5	0.5	0.5	0.6	0.6	-0.6	-0.6	-0.7	0.9
Condit. Reinf. lever presses	0.1	0.1	1.1	0.0	-0.1	-0.0	0.0	0.1	0.1	-0.3	-0.3	-0.4	1.0
Condit. Reinf. active minus inactive responses	0.1	0.2	0.3	-0.5	0.5	0.4	0.4	0.4	0.5	-0.5	-0.4	-0.5	0.5
Condit. Reinf. active-inactive response ratio	0.6	1.0	1.4	-0.9	0.8	0.9	0.8	0.9	1.2	-1.0	-1.1	-1.2	1.2
Condit. Reinf. active responses	0.1	0.1	0.3	0.3	-0.3	-0.3	-0.4	-0.3	-0.3	0.4	0.5	0.4	0.1
Condit. Reinf. inactive responses	0.9	1.3	2.2	1.1	-1.0	-1.0	-1.1	-1.1	-1.2	1.3	1.5	1.4	-0.7
Condit. Reinf. lever presses	0.2	0.4	0.8	-0.7	0.9	0.7	0.7	0.6	0.5	-0.6	-0.4	-0.4	0.3
Condit. Reinf. lever reinforcers received	0.1	0.2	0.3	0.3	-0.4	-0.4	-0.4	-0.3	-0.3	0.5	0.6	0.4	0.3
Conditioned reinforcement - actives	0.6	2.2	3.7	-1.5	1.3	1.7	1.5	1.6	1.6	-1.2	-1.0	-1.1	1.9
Conditioned reinforcement - inactives	0.2	0.4	0.8	-0.5	0.5	0.7	0.7	0.8	0.7	-0.6	-0.4	-0.6	0.9
Conditioned locomotion	2.2	3.2	3.7	-1.8	1.6	1.9	1.8	1.8	1.9	-1.8	-1.7	-1.8	1.9
Patch foraging indifference point 0 sec	0.3	0.7	1.1	-0.9	0.8	0.7	0.8	0.8	0.8	-1.0	-1.0	-0.9	0.8
Patch foraging indifference point AUC	1.3	3.0	4.3	-2.1	1.8	1.9	1.8	1.9	1.8	-1.1	-1.5	-1.5	1.8
Delay disc. indifference point, 0s delay	1.4	1.5	1.9	1.3	-1.4	-1.3	-1.3	-1.3	-1.3	1.3	1.3	1.3	-0.2
Delay disc. indifference point, 16s delay	1.3	1.8	3.4	1.2	-0.6	-1.1	-0.9	-1.2	-1.4	1.4	1.8	1.8	-1.5
Delay disc. indifference point, 2s delay	3.9	4.3	5.8	2.1	-1.6	-2.0	-1.9	-2.2	-2.4	2.1	2.0	2.2	-2.4
Delay disc. indifference point, 24s delay	0.3	0.4	0.8	-0.7	0.9	0.6	0.7	0.5	0.4	-0.8	-0.5	-0.4	-0.9
Delay disc. indifference point, 4s delay	0.0	0.0	0.1	0.0	-0.1	0.0	-0.1	-0.0	-0.0	0.2	0.4	0.3	0.0
Delay disc. indifference point, 8s delay	1.6	2.8	4.3	1.6	-1.1	-1.4	-1.3	-1.5	-1.7	1.8	2.1	2.1	-1.8
Indifference point function ln k	0.3	1.0	1.8	1.2	-0.9	-1.1	-0.9	-1.0	-1.0	0.7	0.9	0.9	-1.3
Indifference point function log k	0.3	1.0	1.8	1.2	-0.9	-1.1	-0.9	-1.0	-1.0	0.7	0.9	0.9	-1.3
Patch foraging total patch changes 0 sec	0.5	1.3	2.0	-1.2	1.2	1.0	1.1	1.1	1.1	-1.4	-1.3	-1.2	0.7
Patch foraging total patch changes 12 sec	1.1	1.4	3.0	-1.4	0.9	1.1	1.0	1.2	1.3	-0.8	-1.1	-1.1	1.7
Patch foraging total patch changes 18 sec	1.4	3.4	4.1	-2.0	2.0	2.0	1.9	1.8	1.9	-1.8	-1.9	-1.8	1.1
Patch foraging total patch changes 24 sec	0.2	0.7	1.2	-1.0	0.8	0.9	0.8	0.8	0.9	-0.5	-0.7	-0.7	1.1
Patch foraging total patch changes 6 sec	1.9	3.2	4.5	-1.9	1.7	1.8	1.7	1.9	1.8	-1.6	-1.7	-1.7	2.1
Patch foraging time to switch 0 sec	1.4	5.4	6.3	2.5	-2.3	-2.3	-2.4	-2.5	-2.4	2.1	2.3	2.2	-2.2
Patch foraging water rate 0 sec	1.7	6.2	7.3	-2.7	2.5	2.5	2.5	2.6	2.5	-2.1	-2.4	-2.4	2.7
Patch foraging water rate 12 sec	0.1	0.5	0.6	-0.6	0.8	0.7	0.8	0.7	0.7	-0.8	-0.7	-0.7	0.7
Patch foraging water rate 18 sec	0.2	0.3	0.7	-0.6	0.8	0.6	0.7	0.5	0.4	-0.7	-0.5	-0.4	0.0
Patch foraging water rate 24 sec	0.6	0.8	1.1	-1.0	1.1	1.0	1.1	1.0	0.9	-0.7	-0.8	-0.8	0.7
Patch foraging water rate 6 sec	0.9	1.3	2.6	-1.3	1.6	1.3	1.4	1.1	1.0	-1.0	-1.2	-1.0	0.3
Seeking ratio, delayed vs. immediate footshock	1.6	2.2	2.7	1.5	-1.6	-1.6	-1.6	-1.5	-1.3	1.7	1.6	1.6	-0.5
Distance traveled before self-admin	0.1	0.1	0.2	-0.3	0.4	0.3	0.3	0.3	0.3	-0.3	-0.5	-0.5	0.2
Distance traveled after self-admin	0.2	0.4	0.7	0.7	-0.7	-0.7	-0.6	-0.5	-0.5	0.8	0.6	0.5	-0.5
Extensor digitorum longus weight	1.6	6.5	8.2	-2.7	2.8	2.6	2.8	2.5	2.4	-2.9	-2.8	-2.6	0.6
Bone: elastic displacement	0.8	1.0	1.9	1.2	-1.4	-1.1	-1.2	-1.1	-0.9	0.6	1.0	0.8	-0.3
Bone: elastic work	0.1	0.2	1.2	-0.2	-0.2	0.1	0.0	0.2	0.4	-0.5	-0.2	-0.3	1.1
Bone: endosteal estimation	0.0	0.0	0.0	0.1	-0.2	-0.0	-0.0	-0.1	0.0	-0.1	-0.1	-0.0	-0.2
Bone: endosteal perimeter	0.0	0.1	0.5	0.1	0.1	-0.0	0.0	-0.1	-0.1	-0.1	-0.2	-0.1	-0.7
Epididymis fat weight	0.3	1.3	2.0	1.0	-1.2	-1.1	-1.1	-1.1	-1.1	1.0	1.2	1.2	-1.4
Delta time in closed arm before/after self-admin	0.0	0.0	0.1	0.2	-0.1	-0.0	-0.0	-0.2	-0.2	0.1	0.2	0.3	-0.3
Delta time in open arm before/after self-admin	0.0	0.1	0.1	0.3	-0.2	-0.3	-0.3	-0.2	-0.2	0.3	0.2	0.2	-0.2
Diff in mean of infusions in LGA sessions	0.8	1.4	1.7	1.2	-1.1	-1.2	-1.2	-1.3	-1.3	1.2	1.2	1.3	-0.8
Delay discount exponential model param	1.4	1.9	2.9	-1.3	0.9	1.1	1.0	1.2	1.4	-1.4	-1.7	-1.7	1.6
Extinction: sum of active levers before priming	0.1	0.2	0.8	0.3	-0.6	-0.4	-0.5	-0.3	-0.2	0.2	0.3	0.3	0.9
Active lever presses in extinction session 6	0.4	0.4	0.8	-0.6	0.6	0.3	0.4	0.3	0.2	-0.9	-0.9	-0.7	0.7
Bone: final force	0.4	0.7	1.0	-0.9	1.0	0.8	0.8	0.8	0.8	-0.9	-1.0	-0.8	0.5
Bone: final moment	0.6	1.0	1.3	-1.1	1.0	0.9	0.9	1.0	1.0	-0.9	-1.1	-1.0	0.8
Food consumed during 24 hour testing period	2.5	5.0	6.1	2.5	-2.5	-2.1	-2.4	-2.4	-2.2	2.3	2.3	2.2	-1.3
Glucose	0.3	0.4	0.7	0.5	-0.7	-0.6	-0.6	-0.6	-0.6	0.8	0.8	0.8	-0.1
Heart weight	1.8	2.9	4.0	-2.0	1.8	1.7	1.7	1.8	1.7	-1.7	-1.6	-1.6	1.4
Delay discount hyperbolic model param	1.4	1.8	2.7	-1.2	0.8	1.1	1.0	1.2	1.4	-1.4	-1.6	-1.6	1.6
Intermittent access intake day 1-15 change	0.1	0.3	0.5	-0.5	0.7	0.7	0.6	0.4	0.4	-0.6	-0.5	-0.4	0.4
Intermittent access intake escalation	0.1	0.4	0.7	-0.6	0.8	0.8	0.7	0.5	0.5	-0.6	-0.6	-0.5	0.5
Intermittent access intake escalation 2	0.1	0.1	0.7	-0.3	0.2	0.2	0.1	0.1	0.2	-0.2	-0.1	-0.1	0.8
Intermitt. access day 1 inactive lever presses	0.0	0.0	0.1	0.2	0.0	-0.0	0.1	0.1	-0.0	-0.4	-0.1	-0.1	-0.1
Intermitt. access day 15 inactive lever presses	0.0	0.1	1.0	0.1	0.5	0.2	0.3	0.0	-0.1	-0.2	-0.1	0.0	-1.0
Intermitt. access escalation Index	0.1	0.3	0.4	0.6	-0.5	-0.6	-0.6	-0.6	-0.7	0.4	0.4	0.4	0.2
Intermittent access day 1 total infusions	0.6	1.7	2.6	-1.2	1.3	1.6	1.5	1.5	1.5	-0.9	-0.8	-0.9	1.5
Intermittent access day 15 total infusions	0.4	1.1	2.0	-1.0	1.3	1.4	1.3	1.1	1.0	-0.8	-0.6	-0.6	0.9
Intermittent access terminal intake (last 3 days)	0.8	1.4	2.3	-1.2	1.4	1.5	1.4	1.3	1.2	-1.0	-0.8	-0.8	0.9
Intermittent access total infusions	2.2	2.7	3.9	-1.7	1.8	2.0	1.9	1.8	1.7	-1.4	-1.3	-1.3	1.3
Intermittent access day 1 locomotion	0.3	0.5	2.7	-0.4	0.3	0.7	0.6	0.7	0.8	-0.3	-0.2	-0.4	1.6
Intermittent access day 15 total locomotion	0.1	0.3	1.1	-0.2	0.3	0.8	0.5	0.5	0.6	-0.2	-0.0	-0.1	1.0
Intermittent access total locomotion	1.6	1.9	3.7	-1.2	1.2	1.7	1.5	1.5	1.6	-0.9	-0.8	-0.9	1.9
Intermittent access standard deviation	0.0	0.1	0.2	0.4	-0.4	-0.2	-0.4	-0.4	-0.3	0.1	0.4	0.4	-0.2
Left kidney weight	3.2	25.8	30.1	-5.5	5.2	5.1	5.1	5.2	5.2	-5.2	-5.1	-5.1	4.1
Right kidney weight	3.4	23.5	27.5	-5.2	4.8	4.9	4.9	4.9	4.9	-4.9	-4.9	-4.8	4.0
Cocaine induced anxiety	0.2	0.6	1.8	0.8	-0.3	-0.6	-0.4	-0.6	-0.8	0.7	0.8	0.8	-1.3
Post-drug Anxiety	0.2	0.2	0.8	0.5	-0.1	-0.3	-0.2	-0.3	-0.4	0.3	0.3	0.4	-0.9
Baseline Anxiety	0.0	0.0	0.2	0.1	-0.3	-0.0	-0.1	0.0	0.2	-0.1	-0.2	-0.2	0.4
Tail length	0.2	0.8	1.3	-1.1	1.2	1.0	1.0	1.0	0.9	-0.7	-0.9	-0.9	0.3
Length with tail	0.3	1.5	2.0	-1.3	1.4	1.2	1.3	1.2	1.1	-1.4	-1.4	-1.3	0.4
Length without tail	0.5	2.4	4.7	-1.4	1.7	1.5	1.6	1.3	1.3	-2.2	-1.8	-1.6	0.2
Times rat made contact with spout	0.1	0.1	0.3	-0.3	0.0	0.1	0.1	0.2	0.3	-0.5	-0.5	-0.4	0.2
Lifetime Intake	2.0	2.4	3.6	-1.6	1.7	1.9	1.8	1.7	1.7	-1.3	-1.1	-1.2	1.4
Liver weight, left	1.4	2.5	3.9	-1.8	1.5	1.6	1.5	1.7	1.7	-1.5	-1.2	-1.3	2.0
Liver weight, right	1.4	2.5	3.4	-1.6	1.8	1.7	1.6	1.6	1.6	-1.8	-1.6	-1.6	0.9
Locomotor activity	1.2	1.9	2.6	-1.6	1.5	1.3	1.4	1.5	1.3	-1.2	-1.2	-1.2	1.1
Locomotor testing distance	0.5	1.1	1.8	-1.3	1.3	1.0	1.1	1.2	1.0	-0.8	-0.9	-0.9	1.1
Locomotor testing rearing	2.0	7.4	8.8	-3.0	2.9	2.9	2.8	2.8	2.7	-2.5	-2.6	-2.6	2.4
Locomotion in novel chamber	0.2	0.3	0.4	0.4	-0.4	-0.6	-0.5	-0.5	-0.5	0.6	0.6	0.6	-0.5
Locomotion in novel chamber post-restriction	0.4	1.2	1.6	1.2	-1.3	-1.2	-1.2	-1.2	-1.2	1.1	0.9	1.0	-0.3
Fecal boli incidents, locomotor time 1	0.0	0.0	0.2	-0.1	0.1	0.1	0.1	0.1	0.1	-0.3	-0.1	-0.1	0.4
Change in fecal boli incidents, locomotor task	0.8	0.9	1.2	1.0	-0.9	-0.8	-0.8	-0.9	-0.9	1.0	1.1	1.0	-1.0
Time >=10cm from walls, locomotor time 1	0.0	0.1	0.2	-0.1	0.5	0.3	0.3	0.2	0.2	-0.0	-0.2	-0.1	0.0
Bouts of movement, locomotor time 1	1.8	2.4	3.3	1.8	-1.5	-1.4	-1.4	-1.5	-1.5	1.3	1.6	1.6	-1.6
Total resting periods, locomotor time 1	2.8	3.2	4.2	2.0	-1.7	-1.7	-1.6	-1.8	-1.8	1.6	2.0	1.9	-1.9
Rest time, locomotor task time 1	0.2	0.3	0.8	0.7	-0.5	-0.4	-0.3	-0.4	-0.4	0.4	0.6	0.6	-0.9
Distance moved, locomotor task time 1	0.2	0.6	1.8	-0.9	0.4	0.5	0.4	0.6	0.7	-0.7	-0.9	-0.9	1.3
Vertical activity count, locomotor time 1	0.0	0.1	1.0	-0.1	-0.3	-0.3	-0.4	-0.2	-0.1	-0.1	-0.2	-0.2	1.0
Time >=10cm from walls, locomotor time 2	0.1	0.2	1.2	0.2	-0.3	-0.0	-0.3	-0.2	-0.0	0.4	0.3	0.3	1.1
Bouts of movement, locomotor time 2	1.5	4.9	6.7	2.6	-2.1	-2.4	-2.2	-2.5	-2.5	1.8	2.0	2.0	-2.1
Total resting periods, locomotor time 2	1.1	4.3	6.0	2.4	-2.0	-2.2	-2.1	-2.3	-2.3	1.6	1.8	1.9	-1.9
Rest time, locomotor task time 2	0.1	0.1	0.3	0.5	-0.5	-0.3	-0.2	-0.2	-0.1	0.1	0.3	0.1	-0.5
Distance moved, locomotor task time 2	0.9	1.2	3.2	-1.2	0.7	0.8	0.8	0.9	1.0	-1.0	-1.1	-1.1	1.8
Vertical activity count, locomotor time 2	0.0	0.1	0.4	-0.1	-0.1	-0.4	-0.4	-0.4	-0.3	-0.1	0.1	0.1	0.6
Light reinforcement 1	0.1	0.4	0.6	-0.5	0.8	0.6	0.6	0.5	0.7	-0.6	-0.5	-0.5	0.6
Light reinforcement 2	0.1	0.1	0.5	-0.4	0.7	0.2	0.3	0.2	0.2	-0.6	-0.3	-0.2	0.1
Bone: marrow area	0.0	0.0	0.0	0.0	-0.2	0.0	0.0	-0.0	0.1	-0.1	-0.1	-0.1	-0.1
Bone: maximum diameter	1.7	3.5	4.3	-2.1	2.1	1.9	2.0	1.9	1.8	-1.9	-2.0	-1.9	0.8
Bone: maximum force	0.2	0.3	0.5	-0.6	0.7	0.6	0.6	0.6	0.6	-0.5	-0.6	-0.5	0.4
Bone: maximum moment	0.2	0.4	0.5	-0.7	0.7	0.7	0.7	0.7	0.7	-0.5	-0.7	-0.6	0.6
Mean time between licks in bursts	0.0	0.1	0.5	0.1	-0.4	-0.2	-0.4	-0.3	-0.2	0.4	0.3	0.3	0.7
Mean num. licks in bursts	0.6	1.7	3.7	1.9	-1.8	-1.2	-1.5	-1.4	-1.0	1.1	1.2	1.0	-0.0
Cd content in liver	0.1	0.1	0.1	-0.1	0.2	0.3	0.3	0.1	0.2	-0.4	-0.3	-0.3	-0.2
Co content in liver	1.0	1.2	1.7	1.2	-1.3	-1.2	-1.3	-1.2	-1.0	1.1	1.0	0.9	-0.5
Cu content in liver	0.2	0.2	0.4	-0.6	0.6	0.3	0.5	0.4	0.3	-0.3	-0.6	-0.4	-0.6
Fe content in liver	3.3	4.1	6.8	-2.3	2.6	2.1	2.2	2.1	1.7	-2.2	-2.1	-1.9	0.0
K content in liver	0.0	0.0	0.0	-0.1	-0.1	-0.2	-0.1	0.1	0.0	-0.0	-0.1	-0.1	-0.1
Mg content in liver	0.2	0.2	0.7	-0.5	0.2	0.3	0.3	0.6	0.5	-0.1	-0.4	-0.4	0.8
Mn content in liver	1.4	1.5	7.1	-1.0	0.3	0.8	0.6	1.1	1.4	-0.8	-0.9	-1.1	2.7
Na content in liver	0.1	0.1	0.1	-0.3	0.2	0.1	0.2	0.3	0.3	-0.4	-0.2	-0.2	-0.3
Rb content in liver	0.2	0.2	0.3	-0.4	0.4	0.4	0.5	0.4	0.4	-0.4	-0.6	-0.5	-0.1
Se content in liver	2.2	2.6	3.7	-1.9	1.7	1.5	1.5	1.8	1.6	-1.4	-1.5	-1.5	1.6
Sr content in liver	0.0	0.0	0.1	-0.0	-0.2	-0.1	-0.2	-0.0	-0.0	0.1	0.1	0.1	0.2
Zn content in liver	0.7	0.9	1.3	-0.9	0.7	0.9	0.9	0.9	1.0	-1.0	-1.1	-1.1	0.4
Bone: minimum diameter	0.2	0.4	0.6	-0.6	0.6	0.7	0.7	0.6	0.7	-0.6	-0.8	-0.7	0.3
Time in familiar zone, hab. session 1	0.2	0.3	0.7	-0.4	0.5	0.5	0.5	0.4	0.4	-0.8	-0.5	-0.6	0.4
Time in novel zone, hab. session 1	0.5	0.5	0.8	-0.9	0.8	0.8	0.8	0.8	0.8	-0.4	-0.6	-0.6	0.6
Total zone transitions, hab. session 1	0.4	0.6	1.5	-0.6	0.8	0.8	0.7	0.6	0.7	-1.2	-0.8	-0.8	0.5
Total locomotion distance, hab. session 1	0.3	0.4	0.6	0.8	-0.6	-0.6	-0.8	-0.8	-0.7	0.2	0.7	0.6	-0.5
Locomotion velocity, hab. session 1	0.9	1.3	1.9	1.4	-1.2	-1.1	-1.3	-1.3	-1.3	0.8	1.2	1.1	-0.8
Time in familiar zone, hab. session 2	0.2	0.2	0.6	-0.5	0.8	0.6	0.6	0.4	0.2	-0.4	-0.5	-0.4	0.1
Time in novel zone, hab. session 2	0.0	0.0	0.1	0.0	-0.1	-0.1	-0.0	-0.0	0.1	0.1	0.2	0.1	-0.3
Total zone transitions, hab. session 2	0.6	0.8	1.8	-0.8	0.5	0.7	0.6	0.8	0.8	-1.0	-1.0	-1.0	1.3
Total locomotion distance, hab. session 2	0.4	0.5	1.0	0.9	-1.0	-0.8	-0.9	-0.9	-0.8	0.4	0.5	0.5	-0.0
Locomotion velocity, hab. session 2	0.2	0.3	0.8	0.7	-0.9	-0.7	-0.8	-0.7	-0.5	0.1	0.3	0.2	0.2
Novel to familiar place preference ratio	1.0	1.3	1.8	-1.1	1.2	1.3	1.2	1.2	1.3	-0.9	-1.2	-1.1	0.8
Novelty place preference	0.9	1.2	1.6	-1.1	1.1	1.3	1.2	1.1	1.3	-0.8	-1.1	-1.1	0.9
Time in novel zone, NPP test	1.3	1.5	2.1	-1.3	1.2	1.5	1.3	1.3	1.4	-0.9	-1.2	-1.1	1.1
Total zone transitions, NPP test	0.1	0.2	0.7	-0.4	0.3	0.3	0.4	0.3	0.2	-0.8	-0.5	-0.5	-0.0
Total locomotion distance, NPP test	0.2	0.3	1.0	-0.4	0.5	0.5	0.5	0.4	0.3	-1.0	-0.7	-0.7	0.2
Locomotion velocity, NPP test	0.2	0.2	0.9	-0.3	0.3	0.3	0.4	0.3	0.2	-1.0	-0.6	-0.6	0.0
Intraocular pressure	0.1	0.1	0.4	-0.2	0.4	0.4	0.3	0.1	0.2	-0.5	-0.5	-0.3	-0.6
Delta distance traveled before/after self-admin	2.2	2.4	2.9	1.6	-1.6	-1.6	-1.5	-1.5	-1.5	1.7	1.7	1.6	-1.3
Delta ambulatory time before/after self-admin	0.4	0.7	1.0	0.8	-0.9	-0.9	-0.8	-0.7	-0.7	1.0	1.0	0.9	-0.5
Parametrial fat weight	0.1	0.2	0.7	-0.3	-0.0	0.3	0.2	0.3	0.4	-0.2	-0.4	-0.4	0.8
Pavlov. Cond. lever latency	0.6	0.7	1.2	0.8	-0.7	-0.6	-0.7	-0.7	-0.7	1.1	1.0	1.0	-1.0
Pavlov. Cond. magazine entry latency	0.2	0.3	0.7	-0.4	0.6	0.4	0.5	0.3	0.3	-0.8	-0.6	-0.6	0.2
Pavlov. Cond. change in total contacts	0.3	0.3	0.5	0.7	-0.7	-0.7	-0.7	-0.7	-0.5	0.5	0.3	0.3	0.1
Pavlov. Cond. index score	0.4	0.5	1.1	-0.6	0.6	0.4	0.5	0.5	0.5	-1.0	-0.9	-0.9	0.9
Pavlov. Cond. latency score	0.1	0.1	0.4	-0.2	0.2	0.1	0.2	0.2	0.2	-0.6	-0.5	-0.5	0.5
Pavlov. Cond. lever contacts	0.4	0.5	0.9	-0.6	0.5	0.4	0.5	0.6	0.6	-1.0	-0.9	-0.9	0.8
Pavlov. Cond. magazine entry number	0.1	0.1	0.4	0.2	-0.3	-0.2	-0.3	-0.1	-0.2	0.6	0.6	0.5	-0.3
Pavlov. Cond. intertrial magazine entries	0.2	0.2	1.3	-0.5	0.1	0.4	0.3	0.5	0.6	0.1	-0.2	-0.2	1.1
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.6	-0.6	0.5	0.4	0.5	0.6	0.6	-1.0	-0.9	-0.9	1.3
Pavlov. Cond. response bias	1.2	1.5	2.6	-1.1	1.3	1.0	1.1	1.0	1.0	-1.6	-1.4	-1.4	0.9
Pavlov. Cond. lever latency	0.1	0.1	0.4	0.3	-0.3	-0.2	-0.2	-0.2	-0.2	0.3	0.2	0.2	-0.6
Pavlov. Cond. magazine entry latency	0.5	0.8	1.3	-0.7	0.9	1.1	1.0	0.6	0.8	-1.1	-0.9	-0.9	0.6
Pavlov. Cond. change in total contacts	0.0	0.0	0.0	0.1	-0.0	0.0	0.0	-0.2	-0.1	-0.2	0.0	0.0	0.0
Pavlov. Cond. index score	0.1	0.2	0.3	-0.3	0.5	0.5	0.5	0.2	0.3	-0.5	-0.4	-0.4	0.5
Pavlov. Cond. latency score	0.0	0.1	0.1	-0.2	0.3	0.4	0.3	0.1	0.2	-0.3	-0.2	-0.2	0.4
Pavlov. Cond. lever contacts	0.2	0.2	0.4	-0.5	0.6	0.4	0.5	0.4	0.3	-0.5	-0.4	-0.4	0.6
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	-0.0	-0.3	-0.3	-0.3	0.1	0.1	0.4	0.1	0.0	0.2
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.3	0.4	-0.5	-0.6	-0.4	-0.2	-0.3	0.3	0.4	0.3	-0.5
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.5	-0.5	0.6	0.7	0.6	0.4	0.5	-0.7	-0.6	-0.5	0.6
Pavlov. Cond. response bias	0.1	0.2	0.4	-0.3	0.4	0.4	0.4	0.2	0.3	-0.5	-0.4	-0.4	0.7
Time in closed arm before self-admin	0.7	1.1	1.8	-1.3	1.3	1.1	1.1	1.1	1.0	-1.0	-0.9	-0.9	0.8
Time in closed arm after self-admin	0.7	0.8	1.4	0.7	-0.4	-0.6	-0.5	-0.9	-1.0	1.0	1.0	1.2	-1.0
Time in open arm before self-admin	0.9	1.1	1.8	1.2	-1.3	-1.1	-1.1	-1.0	-0.9	1.0	1.0	1.0	-0.5
Time in open arm after self-admin	0.3	0.4	1.0	0.7	-1.0	-0.7	-0.8	-0.4	-0.3	0.4	0.4	0.2	0.5
Bone: periosteal estimation	0.2	0.6	0.9	-0.8	0.8	0.8	0.8	0.8	0.8	-0.8	-0.9	-0.8	0.2
Bone: periosteal perimeter	0.2	0.4	0.6	-0.6	0.7	0.6	0.6	0.6	0.5	-0.5	-0.8	-0.7	-0.2
Bone: post-yield work	0.6	1.0	1.7	1.1	-0.6	-0.8	-0.8	-1.0	-1.1	1.2	1.0	1.1	-1.3
Progressive ratio test 1 active lever presses	1.3	2.3	5.0	-1.4	1.3	1.6	1.5	1.7	1.7	-1.1	-1.0	-1.2	2.2
Progressive ratio test 1 breakpoint	1.2	2.0	4.9	-1.3	1.1	1.5	1.4	1.6	1.6	-0.9	-0.9	-1.1	2.2
Progressive ratio test 1 inactive lever presses	0.6	1.7	2.2	-1.2	1.4	1.5	1.5	1.4	1.3	-1.3	-1.1	-1.1	1.1
Progressive ratio test 2 active lever presses	1.3	1.9	2.9	-1.4	1.5	1.7	1.6	1.5	1.4	-1.3	-1.1	-1.1	0.8
Progressive ratio test 2 breakpoint	1.7	2.1	3.2	-1.5	1.6	1.8	1.7	1.6	1.5	-1.4	-1.2	-1.2	0.8
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.3	-0.1	0.4	0.5	0.5	0.4	0.2	-0.3	-0.2	-0.2	-0.1
Incentive Sensitization - Responses	0.6	1.7	2.5	-1.3	1.6	1.5	1.5	1.2	1.1	-1.4	-1.3	-1.2	-0.1
Incentive Sensitization - Breakpoint	0.7	1.5	2.3	-1.2	1.5	1.4	1.4	1.1	1.0	-1.4	-1.3	-1.2	-0.2
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.5	0.5	-0.7	-0.7	-0.7	-0.6	-0.5	0.7	0.7	0.7	0.5
Progressive ratio	0.7	2.2	3.2	1.4	-1.1	-1.2	-1.3	-1.4	-1.5	1.7	1.5	1.6	-1.8
Food seeking constrained by brief footshock	4.6	5.7	7.6	2.5	-2.8	-2.6	-2.7	-2.5	-2.3	2.4	2.5	2.4	-0.7
Seeking ratio, punishment vs. effort	0.2	0.5	1.1	0.8	-1.1	-0.9	-0.9	-0.7	-0.6	0.4	0.6	0.5	0.6
Retroperitoneal fat weight	0.1	0.2	1.6	-0.3	0.4	0.1	0.4	0.2	0.0	-0.5	-0.3	-0.1	-1.3
Reaction time number correct	2.1	7.4	8.8	-3.0	2.9	2.8	2.8	2.9	2.8	-2.6	-2.4	-2.3	2.6
Reaction time mean minus median	0.0	0.0	0.0	0.0	-0.0	0.1	0.0	-0.1	-0.1	0.1	0.0	0.1	0.2
Reaction time mean minus median AUC	0.1	0.5	0.7	-0.7	0.8	0.8	0.8	0.6	0.6	-0.5	-0.7	-0.6	0.5
Reaction time num false alarms	3.9	6.6	8.7	-2.8	2.9	2.6	2.6	2.5	2.5	-2.7	-2.6	-2.5	1.7
Reaction time num false alarms AUC	2.4	5.4	7.1	-2.6	2.7	2.3	2.4	2.3	2.2	-2.4	-2.3	-2.2	1.8
Reaction time trials correct on left	2.1	7.4	8.8	-3.0	2.9	2.8	2.8	2.9	2.8	-2.6	-2.4	-2.3	2.6
Reaction time trials on left	2.2	7.4	8.8	-3.0	2.9	2.8	2.8	2.9	2.8	-2.6	-2.4	-2.3	2.6
Reaction time mean	0.3	0.7	0.9	0.9	-0.9	-0.8	-0.9	-1.0	-0.8	0.9	0.7	0.7	-0.3
Reaction time mean AUC	0.2	0.4	0.7	0.8	-0.8	-0.7	-0.7	-0.8	-0.7	0.7	0.5	0.5	-0.2
Median of all reaction times	0.6	1.0	1.3	1.1	-1.1	-1.0	-1.1	-1.1	-0.9	1.0	0.9	0.8	-0.5
Reaction time omissions	0.1	0.1	0.2	-0.3	0.2	0.2	0.3	0.3	0.4	-0.3	-0.4	-0.4	0.4
Reaction time false alarm rate	0.2	0.2	0.4	-0.5	0.7	0.4	0.4	0.3	0.3	-0.6	-0.6	-0.5	0.0
Reaction time premature initiation rate	0.3	0.5	0.9	0.8	-0.9	-0.7	-0.8	-0.7	-0.6	0.5	0.5	0.5	0.3
Reaction time premature initiations	0.2	0.7	2.5	-0.8	0.6	0.7	0.7	0.7	0.8	-0.8	-0.8	-0.7	1.6
Std. dev. reaction times	0.0	0.1	0.2	0.2	-0.3	-0.3	-0.3	-0.4	-0.3	0.5	0.3	0.3	0.2
Reaction time trials completed	2.2	7.4	8.8	-3.0	2.9	2.8	2.8	2.9	2.8	-2.6	-2.4	-2.3	2.6
Reaction time trials AUC	2.6	9.0	10.8	-3.3	3.2	3.1	3.1	3.2	3.1	-2.9	-2.7	-2.6	2.8
Run reversals in cocaine runway, females	0.4	0.5	1.5	0.5	-0.3	-0.7	-0.4	-0.6	-0.8	0.8	0.6	0.6	-1.2
Run reversals in cocaine runway, males	0.6	0.6	1.1	-0.9	0.6	0.7	0.6	0.7	0.8	-1.1	-1.0	-0.9	0.5
Latency to leave start box in cocaine runway	0.2	0.3	0.8	-0.5	0.9	0.6	0.6	0.4	0.3	-0.5	-0.5	-0.3	-0.3
Latency to leave start box in cocaine runway, F	0.6	0.7	1.2	-1.1	1.1	0.9	0.9	0.9	0.8	-0.6	-0.8	-0.7	0.6
Latency to leave start box in cocaine runway, M	0.2	0.1	1.0	0.2	0.3	0.1	0.2	-0.2	-0.2	-0.3	-0.2	-0.1	-1.0
Std. dev. time between licks in bursts	0.1	0.1	0.4	-0.0	0.3	0.3	0.2	0.2	0.3	-0.5	-0.3	-0.3	0.6
Total sessions with >9 infusions	2.9	3.6	6.0	-2.0	1.8	2.1	2.0	2.1	2.1	-1.3	-1.4	-1.5	2.5
Short access day 1 total inactive lever presses	0.3	0.7	1.0	-0.8	1.0	0.8	0.9	0.7	0.6	-1.0	-0.9	-0.8	0.2
Short access day 10 total inactive lever presses	0.2	1.1	2.1	1.0	-0.8	-1.3	-1.0	-1.2	-1.3	0.7	0.7	0.8	-1.5
Short access day 1 total infusions	1.0	1.9	3.4	-1.5	1.3	1.5	1.4	1.5	1.5	-0.9	-0.9	-1.0	1.8
Short access day 10 total infusions	2.3	3.7	4.7	-2.0	1.8	2.2	2.0	2.2	2.1	-1.6	-1.5	-1.6	2.2
Short access total infusions	1.5	2.1	3.1	-1.5	1.3	1.6	1.5	1.6	1.6	-1.1	-1.0	-1.1	1.8
Short access day 1 locomotion	2.1	3.5	5.3	-2.1	1.9	2.0	1.9	2.0	2.0	-1.3	-1.4	-1.4	2.3
Short access day 10 total locomotion	0.1	0.4	2.8	-0.3	-0.0	0.3	0.1	0.3	0.5	-0.5	-0.4	-0.4	1.7
Short access total locomotion	0.9	1.3	6.9	-0.9	0.4	1.0	0.8	1.1	1.3	-0.6	-0.5	-0.7	2.6
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.1	0.4	0.5	0.5	0.3	0.2	-0.4	-0.3	-0.2	0.2
Compulsive drug intake	0.4	0.6	1.5	-0.4	0.4	0.6	0.6	0.6	0.7	-0.9	-1.0	-1.1	1.2
One hour access (shock baseline)	0.5	1.3	2.0	-1.3	1.4	1.4	1.3	1.1	1.1	-1.1	-0.9	-0.8	0.6
Social response proportion	1.7	2.1	3.2	-1.4	1.4	1.4	1.6	1.4	1.4	-1.8	-1.6	-1.6	0.9
Social responses	0.9	1.2	1.5	-1.1	1.1	1.1	1.2	1.1	1.1	-1.2	-1.2	-1.1	0.8
Social time	2.7	4.3	5.5	2.3	-2.2	-2.1	-2.0	-2.1	-2.2	2.2	1.8	1.9	-1.8
Soleus weight	0.3	0.8	2.9	-0.5	1.0	0.7	0.9	0.5	0.2	-1.1	-0.8	-0.6	-1.7
Bone: stiffness	0.7	1.2	1.9	-1.2	1.4	1.1	1.2	1.1	0.9	-1.3	-1.1	-1.0	0.3
Tibialis anterior weight	3.0	10.4	13.2	-3.4	3.5	3.3	3.5	3.2	3.1	-3.6	-3.4	-3.3	1.0
Time to tail flick, vehicle, before self-admin	2.1	2.6	5.4	-1.7	1.1	1.5	1.4	1.7	1.8	-1.2	-1.3	-1.5	2.3
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.9	-0.3	0.7	0.4	0.4	0.1	-0.0	-0.1	0.0	0.1	-1.0
Time to tail flick, test, before self-admin	0.5	0.6	1.4	0.6	-1.2	-0.9	-1.0	-0.7	-0.5	0.7	0.6	0.5	0.9
Time to tail flick, test, after self-admin	0.4	0.4	0.8	0.5	-0.5	-0.4	-0.5	-0.5	-0.5	0.9	0.9	0.8	-0.9
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.9	0.2	0.0	-0.1	-0.1	-0.3	-0.4	0.1	0.2	0.2	-0.9
Delta time to tail flick, test, before/after SA	0.6	0.7	1.4	-0.9	1.2	1.0	1.0	0.9	0.8	-0.6	-0.7	-0.6	-0.6
Tibia length	0.3	0.9	1.6	-1.0	0.8	0.7	0.8	0.9	0.8	-1.3	-1.1	-1.1	0.7
Ambulatory time before self-admin	0.0	0.0	0.0	0.0	0.2	-0.0	0.0	-0.0	-0.0	0.0	-0.2	-0.1	-0.1
Ambulatory time after self-admin	0.4	0.7	1.1	0.9	-0.8	-0.9	-0.8	-0.7	-0.8	1.0	0.8	0.8	-0.6
Bone: tissue strength	0.7	0.7	1.5	0.9	-1.0	-0.8	-0.9	-0.8	-0.6	1.2	0.9	0.8	0.2
Total heroin consumption	0.0	0.0	0.3	-0.1	0.0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0.0	0.6
Bone: trabecular number	0.0	0.0	0.1	0.2	0.2	-0.1	-0.0	-0.1	-0.1	-0.3	0.0	0.1	0.1
Bone: trabecular spacing	0.0	0.0	0.1	-0.1	-0.2	0.1	0.0	0.1	0.2	0.3	-0.2	-0.2	-0.1
Bone: trabecular thickness	1.5	2.1	2.6	-1.5	1.6	1.4	1.5	1.4	1.4	-1.6	-1.4	-1.4	1.1
Bone: trabecular tissue density	0.3	0.6	0.8	-0.9	0.8	0.8	0.8	0.7	0.6	-0.7	-0.8	-0.9	0.5
Water consumed over 24 hours	0.0	0.1	0.4	-0.1	-0.3	-0.1	-0.2	-0.1	0.2	-0.4	-0.3	-0.3	0.6
Number of responses in last shaping day	2.5	3.2	5.2	-2.3	2.0	2.0	1.9	1.9	1.8	-1.4	-1.3	-1.3	1.7